$319+ Cheap flights from Roanoke to Buffalo (ROA - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/29. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — BUF
Nov 28 — Dec 51
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Roanoke to Buffalo
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Cheapest flights from Roanoke to BuffaloExplore the most affordable flight options available from Roanoke to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
Explore the most affordable flight options available from Roanoke to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2026.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop5h 06m
Sun 11/156:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop5h 29m
Wed 11/116:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop5h 29m
Tue 11/106:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:05 pm -
1 stop4h 14m
Sat 12/53:00 pm -
1 stop4h 12m
Deal found 10/25![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:38 pm -
1 stop5h 21m
Thu 11/126:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:00 pm -
1 stop3h 44m
Thu 11/197:52 pm -
1 stop3h 52m
Deal found 10/25![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:01 am -
2 stops6h 39m
Mon 11/1611:08 am -
1 stop5h 57m
Deal found 10/28![American Airlines logo]()
$431
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:10 am -
1 stop6h 19m
Tue 11/1012:16 pm -
1 stop5h 58m
Deal found 10/28![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:00 am -
1 stop4h 56m
Mon 1/43:27 pm -
1 stop5h 13m
Deal found 10/28![American Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:01 pm -
1 stop6h 35m
Sun 11/156:00 am -
1 stop3h 51m
Deal found 10/27![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops9h 45m
Sat 11/143:26 pm -
1 stop5h 05m
Deal found 10/28![American Airlines logo]()
$510
Best flights from Roanoke to BuffaloDiscover carefully curated flight deals from Roanoke to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
Discover carefully curated flight deals from Roanoke to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2026.
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/296:00 am -
1 stop5h 15m
Sun 4/46:00 am -
1 stop4h 34m
Deal found 10/26![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:05 pm -
1 stop4h 14m
Sat 12/53:00 pm -
1 stop4h 12m
Deal found 10/25![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am -
1 stop6h 21m
Sun 11/156:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop5h 16m
Sun 11/156:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:01 pm -
1 stop6h 35m
Sun 11/156:00 am -
1 stop3h 51m
Deal found 10/27![United Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/243:00 pm -
1 stop3h 26m
Wed 4/286:00 am -
1 stop3h 23m
Deal found 10/28![United Airlines logo]()
$494
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/266:00 am -
2 stops11h 06m
Sat 4/36:00 am -
1 stop4h 34m
Deal found 10/26![Delta logo]()
$483
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:54 pm -
2 stops15h 41m
Mon 11/166:32 pm -
1 stop4h 44m
Deal found 10/28![Delta logo]()
$542
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
1 stop5h 16m
Fri 11/136:32 pm -
1 stop21h 01m
Deal found 10/28![Delta logo]()
$597
Last-minute flights from Roanoke to BuffaloDiscover last-minute flight deals from Roanoke to Buffalo. Data last updated October 29, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Buffalo. Data last updated October 29, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:38 pm -
1 stop5h 21m
Thu 11/126:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$414
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/67:10 am -
1 stop6h 19m
Tue 11/1012:16 pm -
1 stop5h 58m
Deal found 10/28![Delta logo]()
$434
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:35 pm -
1 stop4h 58m
Tue 11/105:40 am -
2 stops9h 52m
Deal found 10/28![American Airlines logo]()
$530
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop5h 29m
Wed 11/116:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop5h 29m
Tue 11/106:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$389
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops9h 45m
Sun 11/153:26 pm -
1 stop5h 05m
Deal found 10/28![American Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:01 pm -
1 stop6h 35m
Sun 11/156:00 am -
1 stop3h 51m
Deal found 10/27![United Airlines logo]()
$439
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am -
1 stop5h 06m
Sun 11/156:00 am -
1 stop4h 37m
Deal found 10/28![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:00 pm -
1 stop3h 44m
Thu 11/197:52 pm -
1 stop3h 52m
Deal found 10/25![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:01 am -
2 stops6h 39m
Mon 11/1611:08 am -
1 stop5h 57m
Deal found 10/28![American Airlines logo]()
$431
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:54 pm -
2 stops15h 41m
Mon 11/166:32 pm -
1 stop4h 44m
Deal found 10/28![Delta logo]()
$542
One-way flights from Roanoke to BuffaloSearch for one-way flight options from Roanoke to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
Search for one-way flight options from Roanoke to Buffalo. Find affordable one-way fares based on user searches. Data last updated October 29, 2026.
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:00 pm -
1 stop3h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![United Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
1 stop6h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![United Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:01 am -
2 stops6h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:52 am -
3 stops49h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$620
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
3 stops16h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![United Airlines logo]()
$1,440
Find flight deals from Roanoke to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $311 (Delta) |
Popular in | August |
Cheapest in | March |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
Use the filters below to find and compare flights from Roanoke to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Mon 3/29
6:00 am-11:15 am
1 stop5h 15m
Buffalo
Sun 4/4
6:00 am-10:34 am
1 stop4h 34m
$319
Quickest round-trip
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Sun 11/8
8:00 pm-11:44 pm
1 stop3h 44m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$333
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Tue 11/10
7:05 am-1:26 pm
1 stop6h 21m
Buffalo
Sun 11/15
6:00 am-10:37 am
1 stop4h 37m
$369
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Sun 11/8
6:00 am-11:16 am
1 stop5h 16m
Buffalo
Sun 11/15
6:00 am-10:37 am
1 stop4h 37m
$369
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Thu 11/5
5:01 am-10:40 am
1 stop5h 39m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$384
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Mon 11/9
6:00 am-9:54 am
1 stop3h 54m
Buffalo
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$384
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Thu 12/3
3:05 pm-7:19 pm
1 stop4h 14m
Buffalo
Sat 12/5
3:00 pm-7:12 pm
1 stop4h 12m
$405
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Wed 11/11
2:01 pm-8:36 pm
1 stop6h 35m
Buffalo
Sun 11/15
6:00 am-9:51 am
1 stop3h 51m
$439
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Fri 3/26
6:00 am-5:06 pm
2 stops11h 06m
Buffalo
Sat 4/3
6:00 am-10:34 am
1 stop4h 34m
$483
RoanokeBuffalo
ROA Roanoke - BUF Buffalo
ROABUF
Roanoke
Sat 4/24
3:00 pm-6:26 pm
1 stop3h 26m
Buffalo
Wed 4/28
6:00 am-9:23 am
1 stop3h 23m
$494
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Roanoke to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Buffalo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Roanoke-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Roanoke-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Roanoke to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Roanoke with our price prediction graph.
ROA-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated October 29, 2026.
Read reviews from past customers who have flown United Airlines and American Airlines from Roanoke to Buffalo. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Overall
7.3
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Overall
7.3
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Entertainment
7.1
Comfort
7.3
Food
6.7
Overall
7.3
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Roanoke to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Roanoke and Buffalo flights
Browse other Roanoke and Buffalo flight options. Last updated on October 29, 2026.
Other flights from Roanoke
Browse through other flights departing from Roanoke. Flights are based on user searches made on Cheapflights and were last updated on October 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Roanoke to Buffalo
Discover the top 2 airlines that operate flights from Roanoke to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$323 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$397 | FlexibilityNo cancel fee | On-time71% |