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$485+ Cheap flights from Panama City (PTY) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Istanbul are usually found in July or April, booked 52 days in advance, depart on a Saturday or Friday and return on a Monday

Cheap flight deals from Panama City to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$868
(KLM)

One-way from

$485
(Mytrip)

Popular in

March

Cheapest in

July

Average price

$1,320

Good round-trip deal

$1,321 or less

Good one-way deal

$848 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Istanbul flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Istanbul flights.
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From Panama City Tocumen Intl to Istanbul
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One-way flight from Panama City Tocumen Intl to Istanbul
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Highest demand for flights based on searches. 0% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Istanbul.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Istanbul.
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Find flight deals from Panama City to Istanbul

Cheapest flights from Panama City to Istanbul
Explore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This KLM deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2610:20 pmPTY - IST
2 stops34h 35mKLM
Wed 12/35:55 pmIST - PTY
2 stops34h 15mKLM
Deal found 10/28$868
This Air France deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:45 pmPTY - IST
2 stops25h 05mMultiple Airlines
Tue 1/135:55 pmIST - PTY
1 stop30h 35mMultiple Airlines
Deal found 10/28$879
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:20 pmPTY - IST
1 stop21h 30mMultiple Airlines
Mon 12/84:50 amIST - PTY
2 stops19h 40mMultiple Airlines
Deal found 10/27$905
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:45 pmPTY - IST
2 stops25h 05mKLM
Mon 12/84:50 amIST - PTY
2 stops19h 40mKLM
Deal found 10/27$919
This Air France deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:20 pmPTY - IST
1 stop21h 30mMultiple Airlines
Tue 11/185:55 pmIST - PTY
1 stop30h 35mMultiple Airlines
Deal found 10/26$966
This KLM deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:45 pmPTY - IST
2 stops25h 05mKLM
Thu 11/205:55 pmIST - PTY
1 stop30h 35mKLM
Deal found 10/27$970

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Panama City to Istanbul Airport that are best for you.

Fly from

Panama City

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 11/26

10:20 pm-4:55 pm

2 stops34h 35m

Istanbul

Wed 12/3

5:55 pm-4:30 pm

1 stop30h 35m

$878

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 3/10

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Tue 3/24

4:50 am-4:30 pm

2 stops19h 40m

$904

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 2/7

10:05 pm-4:55 pm

1 stop34h 50m

Istanbul

Tue 3/31

5:05 pm-4:50 pm

1 stop31h 45m

$915

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 11/27

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Mon 12/8

4:50 am-4:30 pm

2 stops19h 40m

$919

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 11/25

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Mon 12/8

4:50 am-4:30 pm

2 stops19h 40m

$919

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/15

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Tue 2/24

4:50 am-4:30 pm

2 stops19h 40m

$928

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/15

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Wed 2/25

5:55 pm-4:30 pm

1 stop30h 35m

$978

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 2/28

10:05 pm-4:55 pm

1 stop34h 50m

Istanbul

Tue 3/10

4:50 am-8:10 pm

1 stop23h 20m

$989

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 2/6

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Sat 2/14

4:50 am-4:30 pm

2 stops19h 40m

$990

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 2/6

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Sun 2/15

5:55 pm-7:55 pm

1 stop34h 00m

$998

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 16 results
1
2

Compare providers for flights from Panama City to Istanbul

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Istanbul in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Istanbul Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Istanbul Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Istanbul Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Istanbul Airport

How far ahead should I book a flight from Panama City to Istanbul Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Istanbul. Price data was last updated on October 24, 2025.

The best time to book flights from Panama City to Istanbul Airport is 52 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Istanbul Airport?

Currently, July is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $916). Flying from Panama City to Istanbul Airport in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IST?

Find hourly flight availability from Panama City to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Istanbul Airport as you normally would.

How much does it cost to fly round-trip from Panama City to Istanbul Airport?

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated October 28, 2025.
Get a feel of what it's like to fly with United Airlines, Turkish Airlines, and Air Europa from Panama City to Istanbul Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
United Airlines
7.4
Good
9,001 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
Turkish Airlines
7.3
Good
4,031 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.
Air Europa
7.0
Good
568 reviews
United Airlines
7.4
Good
9,001 reviews

Comfort

7.3

Boarding

7.7

Crew

8.1

Food

6.6

Overall

7.4

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Tim,Sep 2025

IAD - GSP

This was pretty bad. It’s chaos at the Dulles boarding gates for the small regional jets because they use one gate to board 3-4 flights at a time. So, it’s difficult knowing where and when to go. There is little space for any size of carrry-on, so most had to gate check their bags. However, the worst of it was that our single flight attendant fell asleep before we took off and the pilot couldn’t do so until she responded to his messages. My wife had to wake her up! So we were a little late leaving. Not to be thwarted, the flight attendant fell asleep right after take off and there was no sight of her during the flight. When the aircraft touched down, a tray of unsecured canned drinks came crashing onto the aisle up front. I can only assume someone didn’t do what they were supposed to. The pilot was great, but I’m sure he must not be happy with this crew member.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Istanbul?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Istanbul. You should not have trouble finding flights to Istanbul from Tocumen Intl; the airport handles an average of 2 outbound flights to Istanbul per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Panama City airport to Istanbul. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • How long is the flight from Panama City to Istanbul Airport?

    There are many flights that can get you from Panama City to Istanbul Airport in 34h 35m. Fly via KLM to get the fastest option. The distance from Panama City to Istanbul Airport is about 6717 mi.

  • What are the cheapest airlines flying from Panama City to Istanbul Airport round-trip?

    Air Europa, at $892, was found to be the cheapest airline from Panama City to Istanbul Airport.Alternate airlines to your destination round-trip include United Airlines and Turkish Airlines. Air Europa is priced at 32% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Panama City to Istanbul Airport?

    Looking at all options, your cheapest flight can be booked for $604. While the most popular route (Panama City Tocumen Intl - Istanbul) can be booked for $975 on average, our data indicates $1,582 when flying from Panama City to Istanbul Airport.

  • Can I find deals for flights from Panama City to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama City to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Istanbul.

  • Can I find deals for business class flights from Panama City to Istanbul?

    Yes. Cheapflights offers flight deals from Panama City to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Istanbul Airport?

    Currently, July is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $916). Flying from Panama City to Istanbul Airport in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

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Top 3 airlines flying from Panama City to Istanbul

Discover the top 3 airlines that operate flights from Panama City to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,066FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,048Average$1,065FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,382FlexibilityNo cancel feeOn-time77%

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