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$454+ Cheap flights from Panama City (PTY) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Istanbul are usually found in July or May, booked 60 days in advance, depart on a Friday or Saturday and return on a Monday

Cheap flight deals from Panama City to Istanbul

Cheapest flights from Panama City to Istanbul
Explore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:50 pm
PTY
-
IST
1 stop22h 30m
KLM
Mon 5/255:20 pm
IST
-
PTY
1 stop31h 30m
KLM
Deal found 1/25$826
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:50 pm
PTY
-
IST
1 stop22h 30m
Multiple Airlines
Sun 11/14:50 am
IST
-
PTY
1 stop23h 20m
Multiple Airlines
Deal found 1/25$827
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:55 pm
PTY
-
IST
2 stops19h 25m
KLM
Wed 5/206:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 1/25$846
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/810:20 pm
PTY
-
IST
2 stops34h 35m
Multiple Airlines
Tue 3/314:25 am
IST
-
PTY
1 stop23h 20m
Multiple Airlines
Deal found 1/25$847
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/910:05 pm
PTY
-
IST
2 stops21h 45m
KLM
Thu 4/306:00 am
IST
-
PTY
1 stop18h 50m
KLM
Deal found 1/25$858
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/710:05 pm
PTY
-
IST
2 stops21h 45m
Multiple Airlines
Tue 3/314:25 am
IST
-
PTY
1 stop23h 20m
Multiple Airlines
Deal found 1/25$859
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:50 pm
PTY
-
IST
1 stop22h 30m
KLM
Sat 5/305:20 pm
IST
-
PTY
1 stop31h 30m
KLM
Deal found 1/25$865
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/810:20 pm
PTY
-
IST
2 stops34h 35m
KLM
Sun 3/85:55 pm
IST
-
PTY
2 stops34h 15m
KLM
Deal found 1/25$879
This KLM deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/219:55 pm
PTY
-
IST
2 stops19h 25m
KLM
Sun 4/265:20 pm
IST
-
PTY
1 stop31h 30m
KLM
Deal found 1/25$880

Find flight deals from Panama City to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$826
(KLM)

One-way from

$454
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,298

Good round-trip deal

$1,095 or less

Good one-way deal

$820 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Istanbul flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Istanbul flights.
Search Deals
From Panama City Tocumen Intl to Istanbul
Search Deals
One-way flight from Panama City Tocumen Intl to Istanbul
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl to Istanbul.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl to Istanbul.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Panama City to Istanbul Airport that are best for you.

Fly from

Panama City

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 5/19

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

Mon 5/25

5:20 pm-4:50 pm

1 stop31h 30m

$846

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 3/11

10:20 pm-4:55 pm

2 stops34h 35m

Istanbul

Wed 3/18

5:55 pm-4:30 pm

1 stop30h 35m

$887

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 5/21

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

Mon 6/8

6:00 am-4:50 pm

1 stop18h 50m

$967

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 4/7

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

Tue 4/14

6:00 am-4:50 pm

1 stop18h 50m

$1,011

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/8

10:20 pm-4:55 pm

2 stops34h 35m

Istanbul

Tue 3/31

6:00 am-7:45 pm

2 stops21h 45m

$1,018

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 2/9

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Wed 2/18

4:50 am-4:30 pm

2 stops19h 40m

$1,064

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 4/13

9:55 pm-1:20 am

2 stops19h 25m

Istanbul

Sat 4/25

5:20 pm-4:50 pm

1 stop31h 30m

$1,077

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/15

6:45 pm-3:50 am

2 stops25h 05m

Istanbul

Tue 2/24

4:50 am-7:55 pm

2 stops23h 05m

$1,078

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 2/9

10:05 pm-3:50 am

2 stops21h 45m

Istanbul

Wed 2/18

4:50 am-4:30 pm

2 stops19h 40m

$1,081

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/15

10:20 pm-3:50 am

1 stop21h 30m

Istanbul

Tue 2/24

4:50 am-7:55 pm

2 stops23h 05m

$1,116

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 19 results
1
2
  • Most accurate provider: When it comes to deals on Panama City-Istanbul Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Istanbul Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Istanbul Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Istanbul Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Istanbul Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Istanbul Airport

How far ahead should I book a flight from Panama City to Istanbul Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Istanbul. Price data was last updated on January 23, 2026.

The best time to book flights from Panama City to Istanbul Airport is 60 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Istanbul Airport?

Currently, October is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $878). Flying from Panama City to Istanbul Airport in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IST?

Find hourly flight availability from Panama City to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 27, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Istanbul Airport as you normally would.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with Turkish Airlines and Air Europa from Panama City to Istanbul Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Turkish Airlines
7.3
Good
4,206 reviews

Entertainment

7.4

Crew

7.8

Food

7.4

Overall

7.3

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.
Turkish Airlines
7.3
Good
4,206 reviews
Turkish Airlines
7.3
Good
4,206 reviews

Entertainment

7.4

Crew

7.8

Food

7.4

Overall

7.3

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.
Air Europa
6.9
Okay
587 reviews
Turkish Airlines
7.3
Good
4,206 reviews

Entertainment

7.4

Crew

7.8

Food

7.4

Overall

7.3

Comfort

7.3

Boarding

7.3

Reviews

1 / 20
6.0
Good

Anonymous,Jan 2026

NQZ - IST

First of all, my flight got delayed. When I had a registration in Astana, the girl who was working on a desk was too lazy to fill out my info and that’s why she gave me only 2 tickets instead of 3. While boarding I realized it and had to talk to another worker who was solving this problem. My seat was near emergency door, people in front were reclining their seats, but I couldn’t- that made me have a little space to sit, move, etc. That was really uncomfortable. So the flight itself also took longer and I didn’t have time to reach another gate for next flight, even tho flight attendant said plane will be in time. I had to go to Turkish Airlines main office, most of workers didn’t speak enough good English to explain properly where it is. It also took me like 1,5 hours to solve. I was not satisfied with the flight at all this time.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Istanbul?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Istanbul. You should not have trouble finding flights to Istanbul from Tocumen Intl; the airport handles an average of 2 outbound flights to Istanbul per day. You should also have plenty of airline options to choose from since 2 airlines have flights from the Panama City airport to Istanbul. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • How long is the flight from Panama City to Istanbul Airport?

    There are many flights that can get you from Panama City to Istanbul Airport in 19h 25m. Fly via KLM to get the fastest option. The distance from Panama City to Istanbul Airport is about 6717 mi.

  • What are the cheapest airlines flying from Panama City to Istanbul Airport round-trip?

    Air Europa, at $877, was found to be the cheapest airline from Panama City to Istanbul Airport. An alternate airline flying to your destination would be Turkish Airlines. Air Europa is priced at 32% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Panama City to Istanbul Airport?

    Looking at all options, your cheapest flight can be booked for $707. While the most popular route (Panama City Tocumen Intl - Istanbul) can be booked for $916 on average, our data indicates $1,498 when flying from Panama City to Istanbul Airport.

  • Can I find deals for flights from Panama City to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama City to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Istanbul.

  • Can I find deals for business class flights from Panama City to Istanbul?

    Yes. Cheapflights offers flight deals from Panama City to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Istanbul Airport?

    Currently, October is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $878). Flying from Panama City to Istanbul Airport in August is currently the most expensive (average of $1,096). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Top 2 airlines flying from Panama City to Istanbul

Discover the top 2 airlines that operate flights from Panama City to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$877Average$1,066FlexibilityNo cancel feeOn-time83%
Turkish AirlinesCheapest$1,197Average$1,358FlexibilityNo cancel feeOn-time77%

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