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$502+ Cheap flights from Panama City (PTY) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Istanbul are usually found in July or April, booked 64 days in advance, depart on a Friday or Saturday and return on a Monday

Cheap flight deals from Panama City to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$878
(Air Europa)

One-way from

$502
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,321

Good round-trip deal

$873 or less

Good one-way deal

$727 or less
From Panama City Tocumen Intl to Istanbul
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One-way flight from Panama City Tocumen Intl to Istanbul
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Highest demand for flights based on searches. 3% potential increase in price ($51 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Istanbul.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Istanbul.
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Find flight deals from Panama City to Istanbul

Cheapest flights from Panama City to Istanbul
Explore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Air Europa deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/99:30 pmPTY - IST
1 stop33h 25mAir Europa
Thu 11/205:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/10$879
This Gotogate deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:25 pmPTY - IST
1 stop33h 30mAir Europa
Tue 10/213:45 pmIST - PTY
1 stop34h 55mAir Europa
Deal found 9/10$1,010
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:00 pmPTY - IST
Nonstop12h 55mMultiple Airlines
Tue 10/218:35 pmIST - PTY
3 stops30h 05mMultiple Airlines
Deal found 9/10$1,123
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:45 pmPTY - IST
2 stops25h 05mMultiple Airlines
Wed 11/124:50 amIST - PTY
1 stop23h 20mMultiple Airlines
Deal found 9/11$1,141
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:45 pmPTY - IST
2 stops25h 05mKLM
Sat 11/295:55 pmIST - PTY
1 stop30h 35mKLM
Deal found 9/11$1,168
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/19:30 pmPTY - IST
1 stop33h 25mAir Europa
Mon 12/155:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 9/10$1,172
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:45 pmPTY - IST
2 stops25h 05mMultiple Airlines
Wed 11/194:50 amIST - PTY
1 stop23h 20mMultiple Airlines
Deal found 9/11$1,181
This KLM deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:50 pmPTY - IST
2 stops24h 35mKLM
Wed 10/155:05 pmIST - PTY
1 stop31h 45mKLM
Deal found 9/11$1,211
This KLM deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3110:20 pmPTY - IST
1 stop21h 30mMultiple Airlines
Mon 12/84:50 amIST - PTY
2 stops19h 40mMultiple Airlines
Deal found 9/10$1,217

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Panama City to Istanbul Airport that are best for you.

Fly from

Panama City

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 2/3

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Fri 2/20

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 2/5

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Sun 2/22

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Tue 2/3

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Mon 2/16

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 2/7

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Sat 2/21

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 2/4

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Thu 2/19

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 2/7

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Mon 2/16

5:15 pm-7:45 pm

1 stop34h 30m

$910

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/8

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Fri 2/20

5:15 pm-7:45 pm

1 stop34h 30m

$942

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 2/5

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Wed 2/18

5:15 pm-7:45 pm

1 stop34h 30m

$942

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Mon 2/2

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Wed 2/18

5:15 pm-7:45 pm

1 stop34h 30m

$942

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 2/8

9:30 pm-2:55 pm

1 stop33h 25m

Istanbul

Wed 2/18

5:15 pm-7:45 pm

1 stop34h 30m

$942

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 21 results
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Best time to book a flight from Panama City to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Istanbul Airport

How far ahead should I book a flight from Panama City to Istanbul Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Istanbul. Price data was last updated on August 29, 2025.

The best time to book flights from Panama City to Istanbul Airport is 64 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Istanbul Airport?

Currently, October is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $916). Flying from Panama City to Istanbul Airport in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IST?

Find hourly flight availability from Panama City to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Panama City to Istanbul Airport in the morning. By choosing this option you can save up to 23% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with United Airlines, Turkish Airlines, and Air Europa from Panama City to Istanbul Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Jared,Feb 2024

LBB - DEN

There were a lot of delays. Not sure if they could be helped, but it made me super nervous about catching my already tight connection. The connection was held for me, but I had to really hurry to make it.
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Jared,Feb 2024

LBB - DEN

There were a lot of delays. Not sure if they could be helped, but it made me super nervous about catching my already tight connection. The connection was held for me, but I had to really hurry to make it.
Turkish Airlines
7.3
Good
3,968 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Jared,Feb 2024

LBB - DEN

There were a lot of delays. Not sure if they could be helped, but it made me super nervous about catching my already tight connection. The connection was held for me, but I had to really hurry to make it.
Air Europa
7.0
Good
556 reviews
United Airlines
7.4
Good
8,937 reviews

Entertainment

7.1

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Food

6.6

Reviews

1 / 20
6.0
Good

Jared,Feb 2024

LBB - DEN

There were a lot of delays. Not sure if they could be helped, but it made me super nervous about catching my already tight connection. The connection was held for me, but I had to really hurry to make it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Istanbul?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Istanbul. You should not have trouble finding flights to Istanbul from Tocumen Intl; the airport handles an average of 2 outbound flights to Istanbul per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Panama City airport to Istanbul. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • How long is the flight from Panama City to Istanbul Airport?

    There are many flights that can get you from Panama City to Istanbul Airport in 33h 25m. Fly via Air Europa to get the fastest option. The distance from Panama City to Istanbul Airport is about 6717 mi.

  • What are the cheapest airlines flying from Panama City to Istanbul Airport round-trip?

    Air Europa, at $892, was found to be the cheapest airline from Panama City to Istanbul Airport.Alternate airlines to your destination round-trip include United Airlines and Turkish Airlines. Air Europa is priced at 32% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest flights from Panama City to Istanbul Airport?

    Looking at all options, your cheapest flight can be booked for $535. While the most popular route (Panama City Tocumen Intl - Istanbul) can be booked for $1,125 on average, our data indicates $1,397 when flying from Panama City to Istanbul Airport.

  • Can I find deals for flights from Panama City to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama City to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Istanbul.

  • Can I find deals for business class flights from Panama City to Istanbul?

    Yes. Cheapflights offers flight deals from Panama City to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Istanbul Airport?

    Currently, October is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $916). Flying from Panama City to Istanbul Airport in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Top 3 airlines flying from Panama City to Istanbul

Discover the top 3 airlines that operate flights from Panama City to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,066FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,048Average$1,059FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,402FlexibilityNo cancel feeOn-time77%

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