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$445+ Cheap flights from Panama City (PTY) to Istanbul (IST)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — IST
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Istanbul are usually found in July or April, booked 64 days in advance, depart on a Friday or Tuesday and return on a Monday

Cheap flight deals from Panama City to Istanbul

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Istanbul (IST). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$985
(KLM)

One-way from

$445
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$1,205

Good round-trip deal

$863 or less

Good one-way deal

$570 or less
From Panama City Tocumen Intl to Istanbul
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One-way flight from Panama City Tocumen Intl to Istanbul
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Highest demand for flights based on searches. 2% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Istanbul.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Istanbul.
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Find flight deals from Panama City to Istanbul

Cheapest flights from Panama City to Istanbul
Explore the most affordable flight options available from Panama City to Istanbul. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This KLM deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:50 pmPTY - IST
1 stop22h 30mKLM
Thu 10/305:55 pmIST - PTY
1 stop30h 35mKLM
Deal found 7/27$985
This Air Europa deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:30 pmPTY - IST
1 stop33h 25mAir Europa
Sun 11/165:15 pmIST - PTY
1 stop34h 30mAir Europa
Deal found 7/27$995
This Air France deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:55 pmPTY - IST
1 stop23h 30mMultiple Airlines
Sun 10/56:10 amIST - PTY
1 stop18h 40mMultiple Airlines
Deal found 7/29$1,003
This Air France deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:55 pmPTY - IST
1 stop23h 30mAir France
Sat 9/204:20 amIST - PTY
2 stops20h 30mAir France
Deal found 7/27$1,116

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Istanbul that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Panama City to Istanbul Airport that are best for you.

Fly from

Panama City

Fly to

Istanbul

Route

Depart

Return

Price

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/17

6:50 pm-1:20 am

1 stop22h 30m

Istanbul

Thu 10/30

5:55 pm-4:30 pm

1 stop30h 35m

$985

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 10/19

8:25 pm-1:55 pm

1 stop33h 30m

Istanbul

Sat 11/1

5:15 pm-7:45 pm

1 stop34h 30m

$995

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 9/18

7:55 pm-3:25 am

1 stop23h 30m

Istanbul

Sun 10/5

6:10 am-4:50 pm

1 stop18h 40m

$1,003

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sat 9/6

7:55 pm-3:25 am

1 stop23h 30m

Istanbul

Sat 9/20

4:20 am-4:50 pm

2 stops20h 30m

$1,116

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Sun 9/14

3:20 am-3:50 am

3 stops40h 30m

$445

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 9/24

9:55 pm-6:40 pm

Nonstop12h 45m

$534

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Thu 10/16

6:50 pm-1:20 am

1 stop22h 30m

$642

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Wed 9/17

9:13 am-6:55 pm

2 stops25h 42m

$756

Panama CityIstanbul

PTY - IST

PTYIST

Panama City Tocumen Intl

Fri 10/3

8:25 pm-1:55 pm

1 stop33h 30m

$771

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Panama City to Istanbul

Have a flexible travel schedule? Discover the best time to fly to Istanbul from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Istanbul Airport

How far ahead should I book a flight from Panama City to Istanbul Airport?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Istanbul. Price data was last updated on July 25, 2025.

The best time to book flights from Panama City to Istanbul Airport is 64 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Istanbul Airport?

Currently, November is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $923). Flying from Panama City to Istanbul Airport in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to IST?

Find hourly flight availability from Panama City to Istanbul. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s optimal to fly from Panama City to Istanbul Airport in the morning. By choosing this option you can save up to 24% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing Istanbul

Get insights into the airlines that provide service to Istanbul. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Istanbul. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with KLM, Air France, and United Airlines from Panama City to Istanbul Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,383 reviews
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air France
7.5
Good
1,465 reviews
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,896 reviews
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,925 reviews
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air Europa
7.0
Good
543 reviews
KLM
7.8
Good
1,383 reviews

Crew

8.4

Overall

7.8

Food

7.3

Comfort

7.7

Entertainment

7.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Istanbul. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Istanbul?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Istanbul. You should not have trouble finding flights to Istanbul from Tocumen Intl; the airport handles an average of 1 outbound flight to Istanbul per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Panama City airport to Istanbul. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • What are the cheapest airlines flying from Panama City to Istanbul Airport round-trip?

    KLM, at $985, was found to be the cheapest airline from Panama City to Istanbul Airport.Alternate airlines to your destination round-trip include Air Europa and Air France. KLM is priced at 26% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Panama City to Istanbul Airport one-way?

    $534 is the cheapest one-way deal found within the past few days, from Turkish Airlines. You may also be able to find cheap deals on KLM and United Airlines, with prices starting from $642 and $756, respectively.

  • What are the cheapest flights from Panama City to Istanbul Airport?

    Looking at all options, your cheapest flight can be booked for $478. While the most popular route (Panama City Tocumen Intl - Istanbul) can be booked for $1,199 on average our data indicates $2,504 when flying from Panama City to Istanbul Airport.

  • Can I find deals for flights from Panama City to Istanbul that include hotel bookings?

    Yes. In addition to deals on Panama City to Istanbul flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Istanbul?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Istanbul.

  • Can I find deals for business class flights from Panama City to Istanbul?

    Yes. Cheapflights offers flight deals from Panama City to Istanbul by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Istanbul Airport?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Istanbul Airport (average of $923). Flying from Panama City to Istanbul Airport in June is currently the most expensive (average of $1,359). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Istanbul Airport?

Book flights to Istanbul Airport if you plan to visit one of these locations
Yalova

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Top 3 airlines flying from Panama City to Istanbul

Discover the top 3 airlines that operate flights from Panama City to Istanbul. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapest$892Average$1,091FlexibilityNo cancel feeOn-time83%
United AirlinesCheapest$1,043Average$1,065FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$1,231Average$1,411FlexibilityNo cancel feeOn-time77%

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