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$1,239+ Cheap flights from Panama City, FL (ECP) to Africa

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — JNB
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Panama City to Africa

Cheapest flights from Panama City to Africa
Explore the most affordable flight options available from Panama City to Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:04 pmECP - NBO
2 stops22h 56mDelta
Thu 1/1511:20 pmNBO - ECP
2 stops32h 31mDelta
Deal found 12/11$2,206

Find flight deals from Panama City to Africa

Keep the following information in mind while searching for Panama City to Africa flight deals. Data was last updated December 12, 2025.

Round-trip from

$1,264
(Qatar Airways)
From Panama City NW Florida Beaches to Africa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Panama City to Africa that are best for you.

Fly from

Panama City

Fly to

Africa

Route

Depart

Return

Price

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Tue 1/6

6:00 am-12:10 am

2 stops34h 10m

Cairo

Tue 1/13

2:10 am-10:51 pm

2 stops28h 41m

$1,239

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Sun 2/15

1:06 pm-11:05 pm

2 stops25h 59m

Cairo

Wed 2/18

1:20 am-9:57 pm

2 stops52h 37m

$1,264

Panama CityNairobi

ECP - NBO

ECPNBO

Panama City NW Florida Beaches

Thu 1/22

3:27 pm-7:15 am

2 stops30h 48m

Nairobi Jomo Kenyatta Intl

Mon 1/26

5:00 pm-9:19 pm

2 stops37h 19m

$1,550

Panama CityNairobi

ECP - NBO

ECPNBO

Panama City NW Florida Beaches

Fri 12/26

2:04 pm-9:10 pm

2 stops22h 06m

Nairobi Jomo Kenyatta Intl

Thu 1/15

11:59 pm-7:52 pm

2 stops28h 53m

$2,206

Panama CityNairobi

ECP - NBO

ECPNBO

Panama City NW Florida Beaches

Fri 12/26

2:04 pm-10:00 pm

2 stops22h 56m

Nairobi Jomo Kenyatta Intl

Thu 1/15

11:20 pm-10:51 pm

2 stops32h 31m

$2,206

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Best time to book a flight from Panama City to Africa

Have a flexible travel schedule? Discover the best time to fly to Africa from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Africa

What is the cheapest time of day to fly from ECP to AF?

Find hourly flight availability from Panama City to Africa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Africa in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Africa

Get insights into the airlines that provide service to Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Africa. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with American Airlines from Panama City to Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,050 reviews
American Airlines
7.2
Good
11,050 reviews

Boarding

7.5

Food

6.5

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Africa?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Africa. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Africa?

    Delta and Qatar Airways can get you from Panama City, Florida to Africa in just under 25h 59m. Your travel time can differ by up to 8h 11m. Panama City, Florida and Africa are separated by a distance of 6561 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Africa?

    The most popular flight routes from Panama City, Florida to Africa are Panama City NW Florida Beaches - Nairobi Jomo Kenyatta Intl, Panama City NW Florida Beaches - Cairo and Panama City NW Florida Beaches - Rabat Sale.

  • Can I find deals for flights from Panama City to Africa that include hotel bookings?

    Yes. In addition to deals on Panama City to Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Africa.

  • Can I find deals for business class flights from Panama City to Africa?

    Yes. Cheapflights offers flight deals from Panama City to Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Panama City to Africa

Discover the top airline that operate flights from Panama City to Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$1,097Average$1,122FlexibilityNo cancel feeOn-time71%

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