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$548+ Cheap flights from Panama City, FL (ECP) to Africa

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — JNB
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Panama City to Africa

Cheapest flights from Panama City to Africa
Explore the most affordable flight options available from Panama City to Africa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Qatar Airways deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:01 am
ECP
-
CAI
2 stops31h 14m
Qatar Airways
Tue 9/292:15 am
CAI
-
ECP
2 stops26h 17m
Qatar Airways
Deal found 1/27$1,480
This Ovago deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:30 am
ECP
-
CAI
2 stops30h 00m
Lufthansa
Sun 5/314:40 am
CAI
-
ECP
2 stops23h 20m
Lufthansa
Deal found 1/27$1,558
This Qatar Airways deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Qatar Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/123:00 pm
ECP
-
NBO
2 stops32h 15m
Qatar Airways
Mon 3/168:45 am
NBO
-
ECP
2 stops38h 23m
Qatar Airways
Deal found 1/25$1,622
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/133:00 pm
ECP
-
CAI
2 stops25h 05m
American Airlines
Mon 3/237:35 pm
CAI
-
ECP
2 stops47h 34m
American Airlines
Deal found 1/26$1,749
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/133:00 pm
ECP
-
CAI
2 stops25h 05m
American Airlines
Tue 3/247:35 pm
CAI
-
ECP
2 stops32h 43m
American Airlines
Deal found 1/26$1,801
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:05 am
ECP
-
CAI
2 stops34h 05m
Delta
Sun 3/222:10 am
CAI
-
ECP
2 stops27h 54m
Delta
Deal found 1/28$1,914

Find flight deals from Panama City to Africa

Keep the following information in mind while searching for Panama City to Africa flight deals. Data was last updated January 28, 2026.

Round-trip from

$1,558
(Ovago)

One-way from

$548
(Virgin Atlantic)
From Panama City NW Florida Beaches to Africa
Search Deals
One-way flight from Panama City NW Florida Beaches to Africa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Africa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Panama City to Africa that are best for you.

Fly from

Panama City

Fly to

Africa

Route

Depart

Return

Price

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Sun 5/24

6:30 am-8:30 pm

2 stops30h 00m

Cairo

Sun 5/31

4:40 am-8:00 pm

2 stops23h 20m

$1,558

Panama CityNairobi

ECP - NBO

ECPNBO

Panama City NW Florida Beaches

Thu 3/12

3:00 pm-7:15 am

2 stops32h 15m

Nairobi Jomo Kenyatta Intl

Mon 3/16

8:45 am-3:08 pm

2 stops38h 23m

$1,622

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Fri 3/13

3:00 pm-11:05 pm

2 stops25h 05m

Cairo

Mon 3/23

7:35 pm-12:09 pm

2 stops47h 34m

$1,749

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Fri 3/13

3:00 pm-11:05 pm

2 stops25h 05m

Cairo

Tue 3/24

7:35 pm-9:18 pm

2 stops32h 43m

$1,801

Panama CityCairo

ECP - CAI

ECPCAI

Panama City NW Florida Beaches

Fri 3/13

7:05 am-12:10 am

2 stops34h 05m

Cairo

Sun 3/22

2:10 am-11:04 pm

2 stops27h 54m

$1,914

Panama CityMarrakech

ECP - RAK

ECPRAK

Panama City NW Florida Beaches

Tue 4/7

11:08 am-7:15 am

1 stop14h 07m

$548

Panama CityMarrakech

ECP - RAK

ECPRAK

Panama City NW Florida Beaches

Tue 4/7

11:08 am-7:15 am

1 stop14h 07m

$548

Panama CityMarrakech

ECP - RAK

ECPRAK

Panama City NW Florida Beaches

Mon 4/6

6:43 pm-7:10 pm

2 stops18h 27m

$558

Panama CityMarrakech

ECP - RAK

ECPRAK

Panama City NW Florida Beaches

Tue 4/7

5:30 pm-5:35 pm

2 stops18h 05m

$558

Panama CityMarrakech

ECP - RAK

ECPRAK

Panama City NW Florida Beaches

Mon 4/6

6:43 pm-7:15 am

1 stop30h 32m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 15 results
1
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Best time to book a flight from Panama City to Africa

Have a flexible travel schedule? Discover the best time to fly to Africa from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Africa
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Africa

Get insights into the airlines that provide service to Africa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Africa. Reviews last updated January 28, 2026.
Get a feel of what it's like to fly with American Airlines from Panama City to Africa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,201 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
American Airlines
7.2
Good
11,201 reviews
American Airlines
7.2
Good
11,201 reviews

Comfort

7.2

Entertainment

6.9

Overall

7.2

Crew

8.0

Food

6.4

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Africa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Africa?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Africa. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Africa?

    Lufthansa, Qatar Airways, and American Airlines can get you from Panama City, Florida to Africa in just under 25h 05m. Your travel time can differ by up to 7h 10m. Panama City, Florida and Africa are separated by a distance of 6561 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Africa?

    The most popular flight routes from Panama City, Florida to Africa are Panama City NW Florida Beaches - Cairo, Panama City NW Florida Beaches - Nairobi Jomo Kenyatta Intl and Panama City NW Florida Beaches - Marrakech Menara.

  • Can I find deals for flights from Panama City to Africa that include hotel bookings?

    Yes. In addition to deals on Panama City to Africa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Africa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Africa.

  • Can I find deals for business class flights from Panama City to Africa?

    Yes. Cheapflights offers flight deals from Panama City to Africa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Panama City to Africa

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to Africa

Discover the top airline that operate flights from Panama City to Africa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$1,097Average$1,122FlexibilityNo cancel feeOn-time71%

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