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Panama

$117+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIA
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated October 27, 2025.

Good round-trip deal

$116 or less

Good one-way deal

$28 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on October 27, 2025.

This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:55 amPTY - MDE
1 stop4h 10mAvianca
Tue 12/238:10 pmMDE - PTY
1 stop4h 50mAvianca
Deal found 10/26$208
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/82:55 amPTY - MDE
1 stop4h 50mAvianca
Tue 11/114:20 amMDE - PTY
1 stop4h 30mAvianca
Deal found 10/26$210
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:45 amPTY - MDE
1 stop4h 20mAvianca
Sun 12/1412:40 pmMDE - PTY
1 stop4h 15mAvianca
Deal found 10/26$213
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:45 amPTY - MDE
1 stop4h 20mAvianca
Sat 12/134:45 amMDE - PTY
1 stop4h 05mAvianca
Deal found 10/27$215
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/302:55 amPTY - MDE
1 stop4h 10mAvianca
Fri 12/59:50 amMDE - PTY
1 stop4h 10mAvianca
Deal found 10/25$216
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/242:55 amPTY - MDE
1 stop4h 10mAvianca
Tue 12/98:10 pmMDE - PTY
1 stop4h 50mAvianca
Deal found 10/25$220
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/312:55 amPTY - MDE
1 stop4h 10mAvianca
Fri 2/68:10 pmMDE - PTY
1 stop4h 30mAvianca
Deal found 10/27$223
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/58:28 amPTY - MDE
Nonstop1h 23mCopa Airlines
Tue 12/96:20 pmMDE - PTY
Nonstop1h 29mCopa Airlines
Deal found 10/25$224
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/262:55 amPTY - MDE
1 stop4h 10mAvianca
Mon 12/112:40 pmMDE - PTY
1 stop4h 15mAvianca
Deal found 10/26$235
This Avianca deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1911:25 amPTY - BOG
1 stop8h 05mAvianca
Mon 1/1910:45 pmBOG - PTY
Nonstop1h 55mAvianca
Deal found 10/27$242
This FlightHub deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:55 amPTY - MDE
1 stop4h 10mAvianca
Sun 12/2112:40 pmMDE - PTY
1 stop4h 15mAvianca
Deal found 10/25$242
This Priceline deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/262:55 amPTY - MDE
1 stop4h 50mAvianca
Sun 11/308:10 pmMDE - PTY
1 stop4h 50mAvianca
Deal found 10/26$244

Find flights from Panama within your budget

 
Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on October 27, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Miami

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Tue 12/2

8:28 am-9:51 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Sun 12/7

6:24 am-7:49 am

Nonstop1h 25m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Thu 11/20

6:54 am-8:18 am

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

Tue 11/25

3:15 pm-4:43 pm

Nonstop1h 28m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sun 2/1

7:10 pm-8:35 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Fri 2/6

9:17 am-10:44 am

Nonstop1h 27m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 2/14

12:52 pm-2:15 pm

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Tue 2/17

10:46 am-12:14 pm

Nonstop1h 28m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 1/26

12:51 pm-2:15 pm

Nonstop1h 24m

Medellín Jose Maria Cordova Intl

Sun 2/1

9:17 am-10:44 am

Nonstop1h 27m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 3/25

9:34 am-10:56 am

Nonstop1h 22m

Medellín Jose Maria Cordova Intl

Sun 3/29

3:32 pm-4:59 pm

Nonstop1h 27m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 2/14

7:00 am-8:18 am

Nonstop1h 18m

Medellín Jose Maria Cordova Intl

Wed 2/18

9:17 am-10:44 am

Nonstop1h 27m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Thu 1/15

9:33 am-10:56 am

Nonstop1h 23m

Medellín Jose Maria Cordova Intl

Wed 1/21

10:46 am-12:14 pm

Nonstop1h 28m

$224

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 2/18

9:34 am-10:56 am

Nonstop1h 22m

Medellín Jose Maria Cordova Intl

Tue 2/24

9:17 am-10:44 am

Nonstop1h 27m

$224

Panama CityBogotá

PTY - BOG

PTYBOG

Panama City Tocumen Intl

Tue 11/25

5:50 pm-7:30 pm

Nonstop1h 40m

Bogotá El Dorado

Tue 12/2

12:15 pm-2:00 pm

Nonstop1h 45m

$250

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, April is the cheapest month in which you can book a flight from Panama (average of $174). Flying from Panama in September will prove the most costly (average of $275). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Panama?

Use this chart to determine the cheapest time to fly round-trip from Panama to Miami. Price data was last updated on December 16, 2024.

Those who are seeking the cheapest fare on flights departing from Panama would be wise to consider leaving during Monday evenings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Monday at noon when fares are usually the most expensive.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, American Airlines, Avianca, United Airlines. These airlines depart to the following popular destinations: Miami.

Copa Airlines
Copa Airlines
From $70
Avianca
Avianca
From $156
Wingo
Wingo
From $33
Air Panama
Air Panama
From $80

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is David Enrique Malek, with prices starting at $28. Explore other affordable destinations below.

David Enrique Malek
David Enrique Malek
From $28
Bogotá El Dorado
Bogotá El Dorado
From $69
Medellín Jose Maria Cordova Intl
Medellín Jose Maria Cordova Intl
From $79
Panama City Tocumen Intl
Panama City Tocumen Intl
From $85

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on October 27, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Read reviews from past customers who have flown Copa Airlines, United Airlines, and American Airlines from Panama. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,561 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
United Airlines
7.4
Good
8,999 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
American Airlines
7.2
Good
11,031 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,464 reviews
Copa Airlines
7.6
Good
1,561 reviews

Comfort

7.4

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.8

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

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Popular international destinations from Panama

The most popular international flight routes departing from Panama we’ve come across at this time.
Flights from Panama City to Bogotá
Flights from Panama City to Madrid
Flights from Panama City to Miami
Flights from Panama City to San Salvador
Flights from Panama City to San José
Flights from Panama City to Atlanta
Flights from Panama City to Mexico City
Flights from Panama City to Amsterdam
Flights from Panama City to Cancún
Flights from Panama City to Managua
Flights from Panama City to Cartagena
Flights from Panama City to Guatemala City
Flights from Panama City to San Francisco
Flights from Panama City to Santo Domingo
Flights from Panama City to Los Angeles
Flights from Panama City to Punta Cana
Flights from Panama City to Fort Lauderdale
Flights from Panama City to Denver

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated October 27, 2025.

  • What is the cheapest month to fly from Panama?

    April is currently the cheapest month to fly from Panama. At this moment in time September is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Cartagena from $137 round trip
    Fly from Panama City to Bogotá from $144 round trip
    Fly from Panama City to Medellín from $152 round trip
    Fly from Panama City to San José from $200 round trip
    Fly from Panama City to Baltimore from $231 round trip

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