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Panama

$134+ Cheap flights from Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIA
may. 5 — may. 121
lun. 5/5
lun. 5/12
1 adult, Economy
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What to know about flights from Panama

Discover essential information about flights departing from Panama, including flight schedules, destinations, airlines operating at the Panama airport, and any specific guidelines or requirements for travelers. Please note that the information is based on the most recent updates available. Data last updated abril 30, 2025.

Good round-trip deal

$37 or less

Good one-way deal

$37 or less
Price to beat on a round-trip flight from Panama.
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Price to beat on a one-way flight from Panama.
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Find flights from Panama

Cheapest flights from Panama
Explore the most affordable flight options available from Panama. Find the lowest fares based on data from user searches, with prices last updated on abril 30, 2025.

mié. 5/73:20 amPTY - MIA
1 stop8h 10mAvianca
dom. 5/113:25 pmMIA - PTY
2 stops20h 00mAvianca
Deal found 4/29$244
jue. 5/2911:20 amPTY - MDE
Nonstop1h 10mAvianca
sáb. 5/311:25 pmMDE - PTY
Nonstop1h 15mAvianca
Deal found 4/29$248
vie. 5/97:20 amPTY - MDE
Nonstop1h 25mCopa Airlines
dom. 5/119:15 amMDE - PTY
Nonstop1h 28mCopa Airlines
Deal found 4/29$250
dom. 5/43:20 amPTY - TPA
1 stop7h 55mAvianca
lun. 5/192:15 pmTPA - PTY
1 stop10h 55mAvianca
Deal found 4/28$268
dom. 5/258:01 amPTY - MIA
Nonstop3h 15mCopa Airlines
vie. 5/306:27 pmMIA - PTY
Nonstop3h 10mCopa Airlines
Deal found 4/29$275
mié. 5/71:20 pmPTY - MIA
Nonstop3h 05mAmerican Airlines
sáb. 7/2612:05 pmMIA - PTY
Nonstop3h 10mAmerican Airlines
Deal found 4/29$318
mié. 5/283:20 amPTY - MDE
1 stop3h 53mMultiple Airlines
vie. 5/3012:10 amMDE - PTY
1 stop6h 35mMultiple Airlines
Deal found 4/29$353
jue. 5/223:20 amPTY - TPA
1 stop7h 55mMultiple Airlines
lun. 5/265:20 amTPA - PTY
2 stops12h 19mMultiple Airlines
Deal found 4/28$355
jue. 6/59:55 amPTY - GIG
1 stop12h 30mAvianca
lun. 6/91:30 amGIG - PTY
1 stop9h 25mAvianca
Deal found 4/29$371
lun. 6/1610:05 pmPTY - MIA
1 stop10h 45mMultiple Airlines
sáb. 6/215:19 pmMIA - PTY
Nonstop3h 10mMultiple Airlines
Deal found 4/29$377
jue. 6/126:34 pmPTY - MCO
2 stops20h 46mMultiple Airlines
jue. 6/199:18 amMCO - PTY
1 stop11h 57mMultiple Airlines
Deal found 4/27$390
dom. 5/1810:05 pmPTY - LGA
2 stops18h 25mMultiple Airlines
mar. 5/209:55 amLGA - PTY
2 stops15h 15mMultiple Airlines
Deal found 4/29$398

Find flights from Panama within your budget

Find flights departing from Panama that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on abril 30, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches

Fly to

Miami

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

mar. 5/13

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

mar. 5/20

1:25 pm-2:40 pm

Nonstop1h 15m

$247

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

vie. 5/9

7:20 am-8:45 am

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

dom. 5/11

9:15 am-10:43 am

Nonstop1h 28m

$250

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

dom. 9/7

10:05 pm-9:50 am

1 stop10h 45m

Miami

vie. 9/12

11:20 am-9:10 pm

1 stop10h 50m

$254

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

dom. 5/25

8:01 am-12:16 pm

Nonstop3h 15m

Miami

vie. 5/30

6:27 pm-8:37 pm

Nonstop3h 10m

$275

Panama CityTampa

PTY - TPA

PTYTPA

Panama City Tocumen Intl

jue. 5/15

10:05 pm-12:15 pm

1 stop13h 10m

Tampa

lun. 5/19

2:15 pm-9:10 pm

1 stop7h 55m

$285

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

dom. 8/10

3:30 pm-11:04 am

1 stop18h 34m

Miami

mar. 9/2

8:40 am-6:37 pm

1 stop10h 57m

$348

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

mié. 5/28

3:20 am-7:13 am

1 stop3h 53m

Medellín Jose Maria Cordova Intl

vie. 5/30

12:10 am-6:45 am

1 stop6h 35m

$353

Panama CityTampa

PTY - TPA

PTYTPA

Panama City Tocumen Intl

jue. 5/22

3:20 am-12:15 pm

1 stop7h 55m

Tampa

lun. 5/26

5:20 am-4:39 pm

2 stops12h 19m

$355

Panama CityRio de Janeiro

PTY - GIG

PTYGIG

Panama City Tocumen Intl

jue. 10/16

9:55 am-12:25 am

1 stop12h 30m

Rio de Janeiro–Galeão Intl

mié. 10/22

7:25 am-9:10 pm

1 stop15h 45m

$361

Panama CityMiami

PTY - MIA

PTYMIA

Panama City Tocumen Intl

dom. 6/15

10:05 pm-9:50 am

1 stop10h 45m

Miami

dom. 6/22

6:27 pm-8:37 pm

Nonstop3h 10m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 60 results
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Best time to book a flight from Panama

Have a flexible travel schedule? Discover the best time to fly from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama

Get recent, data-driven insights about flights from Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama?

Currently, April is the cheapest month in which you can book a flight from Panama (average of $174). Flying from Panama in July will prove the most costly (average of $275). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

When is the cheapest time to fly from Panama?

Use this chart to determine the cheapest time to fly round-trip from Panama to Miami. Price data was last updated on May 26, 2024.

Those who are seeking the cheapest fare on flights departing from Panama would be wise to consider leaving during Friday mornings when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Friday at noon when fares are usually the most expensive.

Which airlines fly from Panama?

For flights departing from Panama check dates and pricing for the following: Copa Airlines, American Airlines, Avianca, United Airlines. These airlines depart to the following popular destinations: Miami.

Copa Airlines

Copa Airlines

From $59

Avianca

Avianca

From $140

United Airlines

United Airlines

From $252

Air Panama

Air Panama

From $78

What is the cheapest place to fly to from Panama?

The cheapest city to fly to from Panama is Panama City Tocumen Intl, with prices starting at $33. Explore other affordable destinations below.

Panama City Tocumen Intl

Panama City Tocumen Intl

From $33

David Enrique Malek

David Enrique Malek

From $34

Medellín Jose Maria Cordova Intl

Medellín Jose Maria Cordova Intl

From $68

Bogotá El Dorado

Bogotá El Dorado

From $70

Airline reviews for flights from Panama

Read reviews and ratings of airlines operating flights from Panama. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Panama travel. Please note that the reviews are sourced from user searches and were last updated on abril 30, 2025. In the last 7 days, Cheapflights users made a total of 2,558,603 searches.
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Avianca
6.7
Okay
2,317 reviews
Delta
8.0
Very good
7,936 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Comfort

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

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Popular international destinations from Panama

The most popular international flight routes departing from Panama we’ve come across at this time.
Flights from Panama City to Bogotá
Flights from Panama City to Miami
Flights from Panama City to Madrid
Flights from Panama City to Atlanta
Flights from Panama City to San José
Flights from Panama City to Amsterdam
Flights from Panama City to San Salvador
Flights from Panama City to Los Angeles
Flights from Panama City to Cancún
Flights from Panama City to Guatemala City
Flights from Panama City to Mexico City
Flights from Panama City to Lima
Flights from Panama City to Boston
Flights from Panama City to Managua
Flights from Panama City to Santo Domingo
Flights from Panama City to San Francisco
Flights from Panama City to Cartagena
Flights from Panama City to Tampa

Related info for your journey

Access useful and relevant information related to your journey from Panama. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated abril 30, 2025.

  • What is the cheapest month to fly from Panama?

    April is currently the cheapest month to fly from Panama. At this moment in time July is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • Where are the cheapest places to fly to from Panama?

    Check out the cheapest flights from Panama to embark to:
    Fly from Panama City to Medellín from $139 round trip
    Fly from Panama City to Bogotá from $140 round trip
    Fly from Panama City to San José from $175 round trip
    Fly from Panama City to Miami from $265 round trip
    Fly from Panama City to Fort Lauderdale from $275 round trip

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