$109+ Cheap flights from Central America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
Find flights from Central America within your budget
Fly to
Route
Depart
Return
San JoséMexico City
SJO San José Juan Santamaria Intl - MEX Mexico City Benito Juarez
SJOMEX
San José Juan Santamaria Intl
Tue 11/10
6:53 am-10:00 am
Nonstop3h 07m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Wed 1/6
7:45 pm-2:10 am
1 stop5h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Thu 10/15
5:55 pm-8:20 pm
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Wed 11/25
5:37 am-8:03 am
Nonstop1h 26m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Tue 9/15
2:48 pm-5:13 pm
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Wed 9/9
3:45 am-6:10 am
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Mon 9/14
5:55 pm-8:20 pm
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Tue 12/1
6:03 pm-8:30 pm
Nonstop1h 27m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Wed 9/30
8:12 am-10:37 am
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
San JoséPanama City
SJO San José Juan Santamaria Intl - PTY Panama City Tocumen Intl
SJOPTY
San José Juan Santamaria Intl
Mon 10/26
10:03 am-12:28 pm
Nonstop1h 25m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
Best time to book a flight from Central America
Have a flexible travel schedule? Discover the best time to fly from Central America with our price prediction graph.
Travel insights for flights from Central America
Get recent, data-driven insights about flights from Central America including ideal travel times, pricing trends, and more.
What is the cheapest month to book a flight from Central America?
Currently, February is the cheapest month in which you can book a flight from Central America (average of $369). Flying from Central America in August will prove the most costly (average of $621). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.
Which airlines fly from Central America?
For flights departing from Central America check dates and pricing for the following: United Airlines, American Airlines, JetBlue, Avianca, Frontier. These airlines depart to the following popular destinations: New York.
What is the cheapest place to fly to from Central America?
The cheapest city to fly to from Central America is David Enrique Malek, with prices starting at $28. Explore other affordable destinations below.
When is the best time to book a flight from Central America?
To ensure you get the cheapest price possible for a flight from Central America, you should look to book at least 65 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
When is the cheapest time to fly from Central America?
Use this chart to determine the cheapest time to fly round-trip from Central America to Newark. Price data was last updated on August 29, 2026.
Those who are seeking the cheapest fare on flights departing from Central America would be wise to consider leaving during Wednesday afternoons when prices are typically at their lowest. When considering other options, price-conscious travelers should avoid Sunday mornings when fares are usually the most expensive.
Airline reviews for flights from Central America
Read reviews and ratings of airlines operating flights from Central America. Gain insights into the quality of service, in-flight amenities, customer experiences, and overall satisfaction to choose the best airline for your Central America travel. Please note that the reviews are sourced from user searches and were last updated on September 4, 2026. In the last 7 days, Cheapflights users made a total of 7,457,451 searches.
Peruse reviews from past customers who have flown Volaris El Salvador,United Airlines, andAmerican Airlines from Central America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
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Popular international destinations from Central America
The most popular international flight routes departing from Central America we’ve come across at this time.
Fly from Central America countries
Fly from one of these departure points in Central America.
Fly from other continents
Choose from these other continents to depart from.
Popular Round-Trip Flight Destinations
Consider these popular destinations that Cheapflights users have chosen when departing from Central America. Routes are based on user searches and were last updated on September 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Related info for your journey
Access useful and relevant information related to your journey from Central America. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated September 4, 2026.