HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Tampa

$407+ Cheap flights from Florence, SC to Tampa (FLO - TPA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — TPA
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to Tampa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florence to Tampa

Cheapest flights from Florence to Tampa
Explore the most affordable flight options available from Florence to Tampa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:15 am
FLO
-
TPA
1 stop3h 59m
American Airlines
Tue 3/1711:15 am
TPA
-
FLO
1 stop6h 06m
American Airlines
Deal found 2/8$407
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
FLO
-
TPA
1 stop3h 59m
American Airlines
Thu 4/211:53 am
TPA
-
FLO
1 stop5h 57m
American Airlines
Deal found 2/7$431
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:16 am
FLO
-
TPA
1 stop5h 27m
American Airlines
Wed 2/2511:05 am
TPA
-
FLO
1 stop6h 16m
American Airlines
Deal found 2/6$467
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:16 am
FLO
-
TPA
1 stop4h 37m
American Airlines
Tue 3/311:30 pm
TPA
-
FLO
1 stop3h 51m
American Airlines
Deal found 2/7$512
This American Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:20 pm
FLO
-
TPA
1 stop6h 08m
American Airlines
Sun 3/111:53 am
TPA
-
FLO
1 stop5h 57m
American Airlines
Deal found 2/6$537

Find flight deals from Florence to Tampa

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Tampa (TPA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(American Airlines)
Provider with most accurate pricing for Florence-Tampa flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Tampa flights.
Search Deals
From Florence to Tampa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Tampa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Florence to Tampa that are best for you.

Fly from

Florence

Fly to

Tampa

Route

Depart

Return

Price

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Tue 3/10

6:15 am-10:14 am

1 stop3h 59m

Tampa

Tue 3/17

11:15 am-5:21 pm

1 stop6h 06m

$407

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Tue 3/17

6:15 am-10:14 am

1 stop3h 59m

Tampa

Thu 4/2

11:53 am-5:50 pm

1 stop5h 57m

$431

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Sat 4/25

4:16 pm-8:13 pm

1 stop3h 57m

Tampa

Sun 4/26

6:58 pm-11:53 pm

1 stop4h 55m

$431

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Sat 2/21

5:16 am-10:43 am

1 stop5h 27m

Tampa

Wed 2/25

11:05 am-5:21 pm

1 stop6h 16m

$467

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 3/27

5:16 am-9:53 am

1 stop4h 37m

Tampa

Tue 3/31

4:49 pm-11:08 pm

1 stop6h 19m

$512

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Thu 3/26

5:16 am-9:53 am

1 stop4h 37m

Tampa

Tue 3/31

1:30 pm-5:21 pm

1 stop3h 51m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Compare providers for flights from Florence to Tampa

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Tampa in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Tampa flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Tampa flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Tampa flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Tampa flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Tampa flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Tampa

Have a flexible travel schedule? Discover the best time to fly to Tampa from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Tampa

What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $58). Flying from Florence, South Carolina to Tampa in November is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Tampa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Tampa?

    For as low as $407, American Airlines can have you in Tampa from Florence, South Carolina in 3h 59m. The distance from Florence, South Carolina to Tampa is about 460 mi.

  • Can I find deals for flights from Florence to Tampa that include hotel bookings?

    Yes. In addition to deals on Florence to Tampa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Tampa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Tampa.

  • Can I find deals for business class flights from Florence to Tampa?

    Yes. Cheapflights offers flight deals from Florence to Tampa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

    Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $58). Flying from Florence, South Carolina to Tampa in November is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Tampa?

Book flights to Tampa if you plan to visit one of these locations
St. Petersburg
Saint Pete Beach
Spring Hill
Tarpon Springs
Brandon
Seminole
Oldsmar
Wesley Chapel
Ruskin
Palm Harbor
Treasure Island
Zephyrhills
Largo
Safety Harbor
New Port Richey
Dunedin
Anna Maria
Holmes Beach
Port Richey
Crystal River

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Tampa

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Miami flights
Charlotte to Orlando flights
Charlotte to Fort Lauderdale flights
Charlotte to Tampa flights
Charleston to Miami flights
Charleston to Fort Lauderdale flights
Charlotte to West Palm Beach flights
Charlotte to Fort Myers flights
Charlotte to Sarasota flights
Charlotte to Jacksonville flights
Greenville to Miami flights
Greenville to Fort Lauderdale flights
Myrtle Beach to Fort Lauderdale flights
Charlotte to Panama City flights
Charlotte to Key West flights
Columbia to Orlando flights
Charleston to West Palm Beach flights
Columbia to Miami flights
Savannah to Miami flights
Myrtle Beach to Miami flights
Charleston to Orlando flights
Greenville to Tampa flights
Charlotte to Pensacola flights
Myrtle Beach to Tampa flights
Charleston to Tampa flights
Columbia to Fort Lauderdale flights
Charleston to Key West flights
Charlotte to Valparaiso flights
Myrtle Beach to Orlando flights
Savannah to Orlando flights
Greenville to Orlando flights
Savannah to Tampa flights
Columbia to Tampa flights
Charlotte to Melbourne flights
Charlotte to Gainesville flights
Myrtle Beach to Fort Myers flights
Augusta to Orlando flights
Charleston to Sarasota flights
Charleston to Pensacola flights
Myrtle Beach to West Palm Beach flights
Greenville to West Palm Beach flights
Columbia to Sarasota flights
Charlotte to St Petersburg flights
Greenville to Orlando Sanford Intl flights
Columbia to West Palm Beach flights
Charleston to Fort Myers flights
Charlotte to Daytona Beach flights
Greenville to Fort Myers flights
Savannah to Fort Myers flights
Greenville to Key West flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights