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$367+ Cheap flights from Florence, SC to Tampa (FLO - TPA)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — TPA
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Florence to Tampa

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Tampa (TPA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$407
(American Airlines)

One-way from

$367
(American Airlines)
From Florence to Tampa
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One-way flight from Florence to Tampa
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Find flight deals from Florence to Tampa

Cheapest flights from Florence to Tampa
Explore the most affordable flight options available from Florence to Tampa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:14 amFLO - TPA
1 stop4h 10mAmerican Airlines
Sat 10/46:52 pmTPA - FLO
1 stop4h 24mAmerican Airlines
Deal found 9/15$407
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:28 amFLO - TPA
1 stop6h 47mAmerican Airlines
Tue 12/166:31 pmTPA - FLO
1 stop4h 22mAmerican Airlines
Deal found 9/15$411
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:29 amFLO - TPA
1 stop5h 32mAmerican Airlines
Fri 11/211:50 pmTPA - FLO
1 stop4h 17mAmerican Airlines
Deal found 9/15$435
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/184:57 pmFLO - TPA
1 stop5h 03mAmerican Airlines
Tue 9/234:49 pmTPA - FLO
1 stop6h 27mAmerican Airlines
Deal found 9/17$472
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:18 amFLO - TPA
2 stops8h 29mAmerican Airlines
Mon 10/63:30 pmTPA - FLO
2 stops8h 33mAmerican Airlines
Deal found 9/16$487

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Tampa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Florence to Tampa that are best for you.

Fly from

Florence

Fly to

Tampa

Route

Depart

Return

Price

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Tue 9/30

6:14 am-10:24 am

1 stop4h 10m

Tampa

Sat 10/4

6:52 pm-11:16 pm

1 stop4h 24m

$407

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 11/19

10:29 am-5:16 pm

1 stop6h 47m

Tampa

Sun 11/23

1:50 pm-6:07 pm

1 stop4h 17m

$411

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 12/12

10:28 am-5:15 pm

1 stop6h 47m

Tampa

Tue 12/16

6:31 pm-10:53 pm

1 stop4h 22m

$411

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 11/14

10:29 am-4:01 pm

1 stop5h 32m

Tampa

Fri 11/21

1:50 pm-6:07 pm

1 stop4h 17m

$435

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 12/12

10:28 am-4:02 pm

1 stop5h 34m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Florence to Tampa

Have a flexible travel schedule? Discover the best time to fly to Tampa from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Tampa

What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $208). Flying from Florence, South Carolina to Tampa in March is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Tampa

Get insights into the airlines that provide service to Tampa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tampa. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown American Airlines from Florence to Tampa. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Overall

7.2

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Overall

7.2

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Florence to Tampa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Tampa?

    For as low as $407, American Airlines can have you in Tampa from Florence, South Carolina in 4h 10m. The distance from Florence, South Carolina to Tampa is about 460 mi.

  • Can I find deals for flights from Florence to Tampa that include hotel bookings?

    Yes. In addition to deals on Florence to Tampa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Tampa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Tampa.

  • Can I find deals for business class flights from Florence to Tampa?

    Yes. Cheapflights offers flight deals from Florence to Tampa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

    Currently, January is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $208). Flying from Florence, South Carolina to Tampa in March is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Tampa?

Book flights to Tampa if you plan to visit one of these locations
St. Petersburg
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Spring Hill
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Largo
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Holmes Beach
Ruskin
Dunedin
Safety Harbor
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Bradenton Beach
Pinellas Park

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Top airline flying from Florence to Tampa

Discover the top airline that operate flights from Florence to Tampa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$310Average$461FlexibilityNo cancel feeOn-time71%

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