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$451+ Cheap flights from Florence, SC to Tampa (FLO - TPA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — TPA
Mar 22 — Mar 291
Sun 3/22
Sun 3/29
1 adult, Economy
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Cheap flight deals from Florence to Tampa

Cheapest flights from Florence to Tampa
Explore the most affordable flight options available from Florence to Tampa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.

This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:16 pm
FLO
-
TPA
1 stop5h 42m
American Airlines
Sun 5/311:41 am
TPA
-
FLO
1 stop4h 09m
American Airlines
Deal found 2/17$451
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:20 pm
FLO
-
TPA
1 stop3h 39m
American Airlines
Mon 4/61:51 pm
TPA
-
FLO
1 stop3h 59m
American Airlines
Deal found 2/18$455
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:16 am
FLO
-
TPA
1 stop4h 37m
American Airlines
Tue 4/74:33 pm
TPA
-
FLO
1 stop6h 09m
American Airlines
Deal found 2/18$487
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:16 am
FLO
-
TPA
1 stop4h 37m
American Airlines
Sun 3/227:35 pm
TPA
-
FLO
1 stop4h 22m
American Airlines
Deal found 2/19$509
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:16 am
FLO
-
TPA
1 stop4h 37m
American Airlines
Sun 4/57:35 pm
TPA
-
FLO
1 stop4h 22m
American Airlines
Deal found 2/18$512
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:16 am
FLO
-
TPA
1 stop4h 37m
American Airlines
Wed 4/84:50 pm
TPA
-
FLO
1 stop7h 02m
American Airlines
Deal found 2/18$516
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:16 am
FLO
-
TPA
2 stops10h 59m
American Airlines
Mon 4/67:35 pm
TPA
-
FLO
1 stop4h 22m
American Airlines
Deal found 2/18$517

Find flight deals from Florence to Tampa

Discover tips and strategies to find the most affordable flight options for your journey from Florence (FLO) to Tampa (TPA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$451
(American Airlines)
Provider with most accurate pricing for Florence-Tampa flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Tampa flights.
Search Deals
From Florence to Tampa
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Tampa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Florence to Tampa that are best for you.

Fly from

Florence

Fly to

Tampa

Route

Depart

Return

Price

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Sat 5/2

4:16 pm-9:58 pm

1 stop5h 42m

Tampa

Sun 5/3

11:41 am-3:50 pm

1 stop4h 09m

$451

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 4/3

6:20 pm-12:29 am

1 stop6h 09m

Tampa

Tue 4/7

9:30 am-3:32 pm

1 stop6h 02m

$512

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 4/1

5:16 am-9:53 am

1 stop4h 37m

Tampa

Sun 4/5

7:35 pm-11:57 pm

1 stop4h 22m

$512

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 4/1

5:16 am-4:15 pm

2 stops10h 59m

Tampa

Mon 4/6

7:35 pm-11:57 pm

1 stop4h 22m

$517

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 4/1

5:16 am-4:15 pm

2 stops10h 59m

Tampa

Sat 4/4

5:30 pm-11:57 pm

1 stop6h 27m

$517

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Wed 4/1

5:16 am-4:15 pm

2 stops10h 59m

Tampa

Tue 4/7

7:00 am-3:32 pm

2 stops8h 32m

$522

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Fri 4/3

5:16 am-9:53 am

1 stop4h 37m

Tampa

Sun 4/5

7:35 pm-11:57 pm

1 stop4h 22m

$537

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Thu 4/2

5:16 am-9:53 am

1 stop4h 37m

Tampa

Sat 4/4

5:30 pm-11:57 pm

1 stop6h 27m

$537

FlorenceTampa

FLO - TPA

FLOTPA

Florence

Thu 3/5

6:20 pm-9:59 pm

1 stop3h 39m

Tampa

Mon 3/9

1:51 pm-5:50 pm

1 stop3h 59m

$537

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

Compare providers for flights from Florence to Tampa

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Florence to Tampa in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Florence, South Carolina-Tampa flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Florence, South Carolina-Tampa flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Florence, South Carolina-Tampa flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Florence, South Carolina-Tampa flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Florence, South Carolina-Tampa flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Florence to Tampa

Have a flexible travel schedule? Discover the best time to fly to Tampa from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Tampa

What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $58). Flying from Florence, South Carolina to Tampa in November is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Tampa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Florence, South Carolina to Tampa?

    For as low as $451, American Airlines can have you in Tampa from Florence, South Carolina in 5h 42m. The distance from Florence, South Carolina to Tampa is about 460 mi.

  • Can I find deals for flights from Florence to Tampa that include hotel bookings?

    Yes. In addition to deals on Florence to Tampa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Tampa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Tampa.

  • Can I find deals for business class flights from Florence to Tampa?

    Yes. Cheapflights offers flight deals from Florence to Tampa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Tampa?

    Currently, May is the cheapest month in which you can book a flight from Florence, South Carolina to Tampa (average of $58). Flying from Florence, South Carolina to Tampa in November is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Tampa?

Book flights to Tampa if you plan to visit one of these locations
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Spring Hill
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Brandon
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Oldsmar
Wesley Chapel
Ruskin
Palm Harbor
Treasure Island
Zephyrhills
Largo
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Holmes Beach
New Port Richey
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