$341+ Cheap flights from Panama City, FL to Syracuse (ECP - SYR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — SYR
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Syracuse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Syracuse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to SyracuseExplore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Panama City to Syracuse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:11 pm -
1 stop6h 48m
Sat 11/286:00 am -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$495
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 21m
Sun 11/296:00 am -
1 stop5h 30m
Deal found 10/29![Delta logo]()
$527
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:16 pm -
1 stop5h 43m
Sat 11/146:00 am -
1 stop5h 30m
Deal found 10/25![Delta logo]()
$551
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 21m
Sat 11/217:12 pm -
1 stop5h 12m
Deal found 10/27![Delta logo]()
$565
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 21m
Sun 11/156:00 am -
1 stop5h 30m
Deal found 10/27![Delta logo]()
$584
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 13m
Sun 11/156:00 am -
2 stops11h 18m
Deal found 10/27![United Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:00 pm -
2 stops10h 39m
Sat 11/147:00 am -
1 stop5h 24m
Deal found 10/25![American Airlines logo]()
$601
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:00 pm -
2 stops9h 41m
Sun 11/156:00 am -
1 stop7h 53m
Deal found 10/27![American Airlines logo]()
$611
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:06 am -
2 stops11h 20m
Sat 11/76:00 am -
1 stop8h 09m
Deal found 10/28![United Airlines logo]()
$624
Best flights from Panama City to SyracuseDiscover carefully curated flight deals from Panama City to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Panama City to Syracuse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:11 pm -
1 stop6h 48m
Sat 11/286:00 am -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$495
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 13m
Sun 11/156:00 am -
2 stops11h 18m
Deal found 10/27![United Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:00 pm -
2 stops10h 39m
Sat 11/147:00 am -
1 stop5h 24m
Deal found 10/25![American Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/204:11 pm -
1 stop6h 48m
Sat 11/286:00 am -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$495
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:16 pm -
1 stop5h 43m
Sat 11/146:00 am -
1 stop5h 30m
Deal found 10/25![Delta logo]()
$551
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:00 pm -
2 stops9h 41m
Sun 11/156:00 am -
1 stop7h 53m
Deal found 10/27![American Airlines logo]()
$611
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 21m
Sat 11/217:12 pm -
1 stop5h 12m
Deal found 10/27![Delta logo]()
$565
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/272:56 pm -
2 stops22h 23m
Sat 1/306:00 am -
1 stop8h 27m
Deal found 10/29![United Airlines logo]()
$700
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 21m
Sun 11/156:00 am -
1 stop5h 30m
Deal found 10/27![Delta logo]()
$584
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:55 pm -
2 stops12h 37m
Sun 11/296:00 am -
1 stop5h 30m
Deal found 10/29![Delta logo]()
$617
Last-minute flights from Panama City to SyracuseDiscover last-minute flight deals from Panama City to Syracuse. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Syracuse. Data last updated October 30, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:06 am -
2 stops11h 20m
Sat 11/76:00 am -
1 stop8h 09m
Deal found 10/28![United Airlines logo]()
$624
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:16 pm -
1 stop5h 43m
Sat 11/146:00 am -
1 stop5h 30m
Deal found 10/25![Delta logo]()
$551
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1012:00 pm -
2 stops10h 39m
Sat 11/147:00 am -
1 stop5h 24m
Deal found 10/25![American Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
1 stop4h 21m
Sun 11/156:00 am -
1 stop5h 30m
Deal found 10/27![Delta logo]()
$584
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:30 am -
2 stops11h 13m
Sun 11/156:00 am -
2 stops11h 18m
Deal found 10/27![United Airlines logo]()
$599
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1112:00 pm -
2 stops9h 41m
Sun 11/156:00 am -
1 stop7h 53m
Deal found 10/27![American Airlines logo]()
$611
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop4h 21m
Sat 11/217:12 pm -
1 stop5h 12m
Deal found 10/27![Delta logo]()
$565
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/194:11 pm -
1 stop6h 48m
Sat 11/286:00 am -
1 stop5h 23m
Deal found 10/29![Delta logo]()
$495
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 21m
Sun 11/296:00 am -
1 stop5h 30m
Deal found 10/29![Delta logo]()
$527
One-way flights from Panama City to SyracuseSearch for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Panama City to Syracuse. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/125:59 pm -
2 stops16h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/127:50 am -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$373
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:06 am -
2 stops13h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![United Airlines logo]()
$461
Find flight deals from Panama City to Syracuse
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Syracuse (SYR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $495 (Delta) |
One-way from | $341 (American Airlines) |
Popular in | July |
Cheapest in | January |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Syracuse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Panama City to Syracuse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Tue 1/12
5:59 pm-11:27 am
2 stops16h 28m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$341
Quickest round-trip
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Tue 1/12
7:50 am-1:29 pm
1 stop4h 39m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$373
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Wed 11/11
9:06 am-11:43 pm
2 stops13h 37m
Syracuse Hancock Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$461
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Thu 11/19
4:11 pm-11:59 pm
1 stop6h 48m
Syracuse Hancock Intl
Sat 11/28
6:00 am-10:23 am
1 stop5h 23m
$495
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Fri 11/20
4:11 pm-11:59 pm
1 stop6h 48m
Syracuse Hancock Intl
Sat 11/28
6:00 am-10:23 am
1 stop5h 23m
$495
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Tue 11/10
5:16 pm-11:59 pm
1 stop5h 43m
Syracuse Hancock Intl
Sat 11/14
6:00 am-10:30 am
1 stop5h 30m
$551
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Sat 11/14
6:00 am-11:21 am
1 stop4h 21m
Syracuse Hancock Intl
Sat 11/21
7:12 pm-11:24 pm
1 stop5h 12m
$565
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Wed 11/11
6:00 am-11:21 am
1 stop4h 21m
Syracuse Hancock Intl
Sun 11/15
6:00 am-10:30 am
1 stop5h 30m
$584
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Wed 11/11
11:30 am-11:43 pm
2 stops11h 13m
Syracuse Hancock Intl
Sun 11/15
6:00 am-4:18 pm
2 stops11h 18m
$599
Panama CitySyracuse
ECP Panama City NW Florida Beaches - SYR Syracuse Hancock Intl
ECPSYR
Panama City NW Florida Beaches
Tue 11/10
12:00 pm-11:39 pm
2 stops10h 39m
Syracuse Hancock Intl
Sat 11/14
7:00 am-11:24 am
1 stop5h 24m
$601
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Panama City to Syracuse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Syracuse in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Syracuse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Syracuse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Syracuse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Syracuse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Syracuse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Syracuse
Have a flexible travel schedule? Discover the best time to fly to Syracuse from Panama City with our price prediction graph.
ECP-SYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Syracuse
Get insights into the airlines that provide service to Syracuse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Syracuse. Reviews last updated October 30, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Panama City to Syracuse by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreNick,Sep 2023
ATL - SYR
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreNick,Sep 2023
ATL - SYR
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
2.0
MediocreNick,Sep 2023
ATL - SYR
Related info for your journey
Find useful and relevant information for your journey from Panama City to Syracuse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Syracuse?
Book flights to Syracuse if you plan to visit one of these locationsEast Syracuse
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Panama City and Syracuse flights
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Other flights from Panama City
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Explore flights to Syracuse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Top 2 airlines flying from Panama City to Syracuse
Discover the top 2 airlines that operate flights from Panama City to Syracuse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$288 | Average$466 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$338 | Average$371 | FlexibilityNo cancel fee | On-time71% |