What’s the fastest layover option from Sioux Falls to St. Louis?

Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 4h 49m.

What’s the cheapest layover airport for flights from Sioux Falls to St. Louis?

Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $278.

Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?

Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 1h 01m.

What’s the top layover airport for flights from Sioux Falls to St. Louis?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Sioux Falls to St. Louis on Cheapflights.

How long is the flight from Sioux Falls to St. Louis?

Departing from Sioux Falls to St. Louis will take you 3h 39m. There are 470 mi between Sioux Falls and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?

Our cheapest airline available from Sioux Falls to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $228 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $241 and $253 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.

What is the cheapest day to fly from Sioux Falls to St. Louis?

Travelers seeking maximum savings on their Sioux Falls to St. Louis flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Sioux Falls to St. Louis?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Sioux Falls to St. Louis.

Most accurate provider : When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?

Yes. In addition to deals on Sioux Falls to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Sioux Falls to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to St. Louis.

Can I find deals for business class flights from Sioux Falls to St. Louis?

Yes. Cheapflights offers flight deals from Sioux Falls to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$126+ Flights from Sioux Falls to St. Louis

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Cheap flight deals from Sioux Falls to St. Louis

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$152 (Frontier)
One-way from	$126 (United Airlines)
Popular in	December
Cheapest in	April
Average price	$308

Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.

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From Sioux Falls Joe Foss Field to Lambert-St Louis

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One-way flight from Sioux Falls Joe Foss Field to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($49 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Sioux Falls to St. Louis

Cheapest flights from Sioux Falls to St. Louis
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

Fri 10/245:14 pmFSD - STL

1 stop6h 44mUnited Airlines

Tue 10/285:24 pmSTL - FSD

1 stop4h 22mUnited Airlines

Deal found 9/28

$229

Thu 12/47:19 pmFSD - STL

1 stop4h 19mAmerican Airlines

Sun 12/75:14 amSTL - FSD

1 stop7h 08mAmerican Airlines

Deal found 9/28

$249

Thu 10/25:00 amFSD - STL

1 stop3h 37mDelta

Mon 10/65:31 pmSTL - FSD

1 stop5h 26mDelta

Deal found 9/28

$279

Thu 10/28:00 amFSD - STL

1 stop6h 27mUnited Airlines

Sat 10/43:23 pmSTL - FSD

1 stop6h 59mUnited Airlines

Deal found 9/28

$289

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Sat 10/187:00 amSTL - FSD

1 stop5h 42mAmerican Airlines

Deal found 9/28

$299

Wed 10/17:00 amFSD - STL

1 stop4h 52mAmerican Airlines

Sun 10/58:03 pmSTL - FSD

1 stop3h 56mAmerican Airlines

Deal found 9/28

$324

Wed 10/111:52 amFSD - STL

1 stop4h 40mUnited Airlines

Sun 10/55:15 amSTL - FSD

1 stop5h 27mUnited Airlines

Deal found 9/26

$339

Fri 10/178:00 amFSD - STL

1 stop6h 27mUnited Airlines

Sun 10/195:28 pmSTL - FSD

1 stop4h 54mUnited Airlines

Deal found 9/28

$347

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Mon 10/204:34 pmSTL - FSD

1 stop6h 08mAmerican Airlines

Deal found 9/28

$377

Fri 10/177:28 pmFSD - STL

1 stop13h 39mFrontier

Sun 10/1911:32 amSTL - FSD

2 stops31h 01mFrontier

Deal found 9/27

$413

Best flights from Sioux Falls to St. Louis
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 29, 2025.

Fri 10/245:14 pmFSD - STL

1 stop6h 44mUnited Airlines

Mon 10/275:24 pmSTL - FSD

1 stop4h 22mUnited Airlines

Deal found 9/28

$229

Fri 12/57:19 pmFSD - STL

1 stop4h 40mAmerican Airlines

Sun 12/78:38 amSTL - FSD

1 stop4h 56mAmerican Airlines

Deal found 9/28

$229

Wed 3/45:15 amFSD - STL

1 stop3h 39mDelta

Sat 3/75:30 pmSTL - FSD

1 stop5h 28mDelta

Deal found 9/26

$229

Fri 10/245:14 pmFSD - STL

1 stop6h 44mUnited Airlines

Tue 10/285:24 pmSTL - FSD

1 stop4h 22mUnited Airlines

Deal found 9/28

$229

Thu 12/47:19 pmFSD - STL

1 stop4h 19mAmerican Airlines

Sun 12/75:14 amSTL - FSD

1 stop7h 08mAmerican Airlines

Deal found 9/28

$249

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Sat 10/187:00 amSTL - FSD

1 stop5h 42mAmerican Airlines

Deal found 9/28

$299

Fri 10/178:00 amFSD - STL

1 stop6h 27mUnited Airlines

Sun 10/195:28 pmSTL - FSD

1 stop4h 54mUnited Airlines

Deal found 9/28

$347

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Mon 10/204:34 pmSTL - FSD

1 stop6h 08mAmerican Airlines

Deal found 9/28

$377

Last-minute flights from Sioux Falls to St. Louis
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated September 29, 2025 and is based on user searches.

Wed 10/17:00 amFSD - STL

1 stop4h 52mAmerican Airlines

Sun 10/58:03 pmSTL - FSD

1 stop3h 56mAmerican Airlines

Deal found 9/28

$324

Wed 10/111:52 amFSD - STL

1 stop4h 40mUnited Airlines

Sun 10/55:15 amSTL - FSD

1 stop5h 27mUnited Airlines

Deal found 9/26

$339

Thu 10/25:00 amFSD - STL

1 stop3h 37mDelta

Mon 10/65:31 pmSTL - FSD

1 stop5h 26mDelta

Deal found 9/28

$279

Thu 10/28:00 amFSD - STL

1 stop6h 27mUnited Airlines

Sat 10/43:23 pmSTL - FSD

1 stop6h 59mUnited Airlines

Deal found 9/28

$289

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Sat 10/187:00 amSTL - FSD

1 stop5h 42mAmerican Airlines

Deal found 9/28

$299

Thu 10/166:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Mon 10/204:34 pmSTL - FSD

1 stop6h 08mAmerican Airlines

Deal found 9/28

$377

Thu 10/163:19 pmFSD - STL

1 stop17h 48mFrontier

Sun 10/197:52 pmSTL - FSD

1 stop22h 41mFrontier

Deal found 9/28

$424

Fri 10/178:00 amFSD - STL

1 stop6h 27mUnited Airlines

Sun 10/195:28 pmSTL - FSD

1 stop4h 54mUnited Airlines

Deal found 9/28

$347

Fri 10/177:28 pmFSD - STL

1 stop13h 39mFrontier

Sun 10/1911:32 amSTL - FSD

2 stops31h 01mFrontier

Deal found 9/27

$413

Fri 10/245:14 pmFSD - STL

1 stop6h 44mUnited Airlines

Tue 10/285:24 pmSTL - FSD

1 stop4h 22mUnited Airlines

Deal found 9/28

$229

One-way flights from Sioux Falls to St. Louis
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 29, 2025.

Tue 10/219:30 amFSD - STL

1 stop7h 02mUnited Airlines

Deal found 9/28

$126

Mon 10/207:28 pmFSD - STL

1 stop13h 39mFrontier

Deal found 9/28

$149

Mon 10/206:11 pmFSD - STL

2 stops24h 25mMultiple Airlines

Deal found 9/28

$154

Tue 10/211:29 pmFSD - STL

3 stops51h 06mMultiple Airlines

Deal found 9/28

$280

Sun 10/268:00 amFSD - STL

1 stop6h 25mUnited Airlines

Deal found 9/28

$289

Sun 10/266:27 pmFSD - STL

1 stop5h 27mAmerican Airlines

Deal found 9/27

$295

Sun 10/265:20 amFSD - STL

1 stop3h 31mDelta

Deal found 9/29

$320

Cheapflights Fare Finder

Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 10/24

5:14 pm-11:58 pm

1 stop6h 44m

Lambert-St Louis

Mon 10/27

5:24 pm-9:46 pm

1 stop4h 22m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 12/5

7:19 pm-11:59 pm

1 stop4h 40m

Lambert-St Louis

Sun 12/7

8:38 am-1:34 pm

1 stop4h 56m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 3/4

5:15 am-8:54 am

1 stop3h 39m

Lambert-St Louis

Sat 3/7

5:30 pm-10:58 pm

1 stop5h 28m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 10/24

5:14 pm-11:58 pm

1 stop6h 44m

Lambert-St Louis

Tue 10/28

5:24 pm-9:46 pm

1 stop4h 22m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 12/4

7:19 pm-11:38 pm

1 stop4h 19m

Lambert-St Louis

Sun 12/7

5:14 am-12:22 pm

1 stop7h 08m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 10/16

6:27 pm-11:54 pm

1 stop5h 27m

Lambert-St Louis

Sat 10/18

7:00 am-12:42 pm

1 stop5h 42m

$299

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 10/17

8:00 am-2:27 pm

1 stop6h 27m

Lambert-St Louis

Sun 10/19

5:28 pm-10:22 pm

1 stop4h 54m

$347

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 10/16

6:27 pm-11:54 pm

1 stop5h 27m

Lambert-St Louis

Mon 10/20

4:34 pm-10:42 pm

1 stop6h 08m

$377

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Tue 10/21

9:30 am-4:32 pm

1 stop7h 02m

$126

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Mon 10/20

6:11 pm-6:36 pm

2 stops24h 25m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/28

Showing 1-10 of 14 results

Compare providers for flights from Sioux Falls to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in September.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Sioux Falls to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to St. Louis

Prices

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $311). Flying from Sioux Falls to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to STL?

It’s typically best to fly out from Sioux Falls to St. Louis in the evening. Doing so could potentially save you 43% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,964 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,924 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,964 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

How long is the flight from Sioux Falls to St. Louis?
Departing from Sioux Falls to St. Louis will take you 3h 39m. There are 470 mi between Sioux Falls and St. Louis. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?
Our cheapest airline available from Sioux Falls to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $228 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $241 and $253 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.
Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?
Yes. In addition to deals on Sioux Falls to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Sioux Falls to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to St. Louis.
Can I find deals for business class flights from Sioux Falls to St. Louis?
Yes. Cheapflights offers flight deals from Sioux Falls to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Sioux Falls to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $311). Flying from Sioux Falls to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to St. Louis

Top 3 airlines flying from Sioux Falls to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$228	Average$293	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$241	Average$374	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$253	Average$290	FlexibilityNo cancel fee	On-time71%

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$126+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Sioux Falls to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Sioux Falls to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Sioux Falls to St. Louis

Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.

Compare providers for flights from Sioux Falls to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in September.

Best time to book a flight from Sioux Falls to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to St. Louis

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

What is the cheapest time of day to fly from FSD to STL?

What’s the top layover airport for flights from Sioux Falls to St. Louis?

What’s the fastest layover option from Sioux Falls to St. Louis?

What’s the fastest layover option from Sioux Falls to St. Louis?

Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Sioux Falls to St. Louis?

What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?

Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?

How can I find direct flights from Sioux Falls to St. Louis?

Can I find deals for business class flights from Sioux Falls to St. Louis?

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Sioux Falls to St. Louis

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Top 3 airlines flying from Sioux Falls to St. Louis

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Cheapest flights from Sioux Falls to St. Louis
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 29, 2025.