What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?

Our cheapest airline available from Sioux Falls to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $228 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $241 and $253 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.

What is the cheapest day to fly from Sioux Falls to St. Louis?

Travelers seeking maximum savings on their Sioux Falls to St. Louis flight should consider departing on Thursday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Sioux Falls to St. Louis?

American Airlines, Delta and United Airlines are the most popular airlines when flying from Sioux Falls to St. Louis.

What is the cheapest day to fly round-trip from Sioux Falls to St. Louis?

Users have found that leaving on a Wednesday can be a cost-effective option. It’s possible to save up to 74% on your flight compared to booking on days when demand is much higher.

What is the cheapest month to fly from Sioux Falls to St. Louis?

The best pricing can be found in the month of April. Prices to St. Louis from Sioux Falls average $340. You can even find prices in April for less than $340, as users have found deals to St. Louis from as low as $228. The month of December appears to be one of the more expensive times to travel to St. Louis from Sioux Falls. Flying in the targeted month can save you up to 37%.

Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?

Yes. In addition to deals on Sioux Falls to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Sioux Falls to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to St. Louis.

Can I find deals for business class flights from Sioux Falls to St. Louis?

Yes. Cheapflights offers flight deals from Sioux Falls to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$228+ Flights from Sioux Falls to St. Louis

Q: How much does it cost to fly round-trip from Sioux Falls to St. Louis?

Airfare is below average for this route at the moment. Sioux Falls to St. Louis flights typically cost between $253 and $418 in September. The cheapest round-trip price found within the last 3 days was $229 on United Airlines (Sep 10-Sep 13).

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Cheap flight deals from Sioux Falls to St. Louis

Round-trip from	$229 (United Airlines)
One-way from	$228 (American Airlines)
Popular in	December
Cheapest in	April
Average price	$288

From Sioux Falls Joe Foss Field to Lambert-St Louis

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One-way flight from Sioux Falls Joe Foss Field to Lambert-St Louis

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Highest demand for flights based on searches. 12% potential increase in price ($49 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Sioux Falls to St. Louis

Cheapest flights from Sioux Falls to St. Louis
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Wed 9/105:06 pmFSD - STL

1 stop6h 47mUnited Airlines

Sat 9/135:30 pmSTL - FSD

1 stop4h 42mUnited Airlines

Deal found 8/13

$229

Sun 8/172:57 pmFSD - STL

1 stop18h 14mFrontier

Tue 8/197:54 pmSTL - FSD

1 stop18h 18mFrontier

Deal found 8/13

$246

Thu 8/146:03 pmFSD - STL

1 stop5h 48mAmerican Airlines

Sat 8/167:23 amSTL - FSD

1 stop4h 26mAmerican Airlines

Deal found 8/14

$289

Fri 8/295:00 amFSD - STL

1 stop3h 36mDelta

Tue 9/25:30 pmSTL - FSD

1 stop6h 16mDelta

Deal found 8/13

$299

Wed 9/101:19 pmFSD - STL

1 stop6h 56mAmerican Airlines

Sat 9/136:29 amSTL - FSD

2 stops11h 43mAmerican Airlines

Deal found 8/13

$327

Fri 10/245:05 pmFSD - STL

1 stop6h 13mAmerican Airlines

Sun 10/267:01 amSTL - FSD

1 stop5h 46mAmerican Airlines

Deal found 8/12

$334

Fri 8/296:03 pmFSD - STL

1 stop5h 48mAmerican Airlines

Sun 9/77:16 amSTL - FSD

1 stop5h 23mAmerican Airlines

Deal found 8/12

$343

Wed 9/102:08 pmFSD - STL

1 stop6h 38mUnited Airlines

Fri 9/125:15 amSTL - FSD

1 stop5h 26mUnited Airlines

Deal found 8/13

$348

Thu 8/142:57 pmFSD - STL

1 stop18h 14mFrontier

Sat 8/162:52 pmSTL - FSD

2 stops23h 10mFrontier

Deal found 8/14

$370

Best flights from Sioux Falls to St. Louis
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Wed 9/105:06 pmFSD - STL

1 stop6h 47mUnited Airlines

Sat 9/135:30 pmSTL - FSD

1 stop4h 42mUnited Airlines

Deal found 8/13

$229

Wed 9/105:00 amFSD - STL

1 stop5h 37mDelta

Sat 9/136:00 amSTL - FSD

1 stop6h 11mDelta

Deal found 8/13

$229

Wed 9/101:19 pmFSD - STL

1 stop6h 56mAmerican Airlines

Sat 9/136:29 amSTL - FSD

2 stops11h 43mAmerican Airlines

Deal found 8/13

$327

Fri 1/165:15 amFSD - STL

1 stop3h 39mDelta

Sun 1/186:30 amSTL - FSD

1 stop6h 05mDelta

Deal found 8/13

$229

Fri 8/295:00 amFSD - STL

1 stop3h 36mDelta

Tue 9/25:30 pmSTL - FSD

1 stop6h 16mDelta

Deal found 8/13

$299

Wed 12/35:32 amFSD - STL

1 stop5h 34mAmerican Airlines

Sun 12/74:08 pmSTL - FSD

1 stop4h 52mAmerican Airlines

Deal found 8/13

$334

Wed 9/102:08 pmFSD - STL

1 stop6h 38mUnited Airlines

Fri 9/125:15 amSTL - FSD

1 stop5h 26mUnited Airlines

Deal found 8/13

$348

Fri 10/245:05 pmFSD - STL

1 stop6h 13mAmerican Airlines

Sun 10/267:01 amSTL - FSD

1 stop5h 46mAmerican Airlines

Deal found 8/12

$334

Fri 8/296:03 pmFSD - STL

1 stop5h 48mAmerican Airlines

Sun 9/77:16 amSTL - FSD

1 stop5h 23mAmerican Airlines

Deal found 8/12

$343

Fri 1/1612:27 pmFSD - STL

2 stops11h 05mAmerican Airlines

Sun 1/185:57 amSTL - FSD

1 stop5h 38mAmerican Airlines

Deal found 8/13

$357

Last-minute flights from Sioux Falls to St. Louis
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated August 14, 2025 and is based on user searches.

Thu 8/146:03 pmFSD - STL

1 stop5h 48mAmerican Airlines

Sat 8/167:23 amSTL - FSD

1 stop4h 26mAmerican Airlines

Deal found 8/14

$289

Thu 8/142:57 pmFSD - STL

1 stop18h 14mFrontier

Sat 8/162:52 pmSTL - FSD

2 stops23h 10mFrontier

Deal found 8/14

$370

Sun 8/172:57 pmFSD - STL

1 stop18h 14mFrontier

Tue 8/197:54 pmSTL - FSD

1 stop18h 18mFrontier

Deal found 8/13

$246

Tue 8/267:01 amFSD - STL

1 stop4h 49mAmerican Airlines

Thu 8/287:59 pmSTL - FSD

1 stop4h 29mAmerican Airlines

Deal found 8/13

$590

Fri 8/295:00 amFSD - STL

1 stop3h 36mDelta

Tue 9/25:30 pmSTL - FSD

1 stop6h 16mDelta

Deal found 8/13

$299

Fri 8/296:03 pmFSD - STL

1 stop5h 48mAmerican Airlines

Sun 9/77:16 amSTL - FSD

1 stop5h 23mAmerican Airlines

Deal found 8/12

$343

Wed 9/105:06 pmFSD - STL

1 stop6h 47mUnited Airlines

Sat 9/135:30 pmSTL - FSD

1 stop4h 42mUnited Airlines

Deal found 8/13

$229

Wed 9/101:19 pmFSD - STL

1 stop6h 56mAmerican Airlines

Sat 9/136:29 amSTL - FSD

2 stops11h 43mAmerican Airlines

Deal found 8/13

$327

Wed 9/102:08 pmFSD - STL

1 stop6h 38mUnited Airlines

Fri 9/125:15 amSTL - FSD

1 stop5h 26mUnited Airlines

Deal found 8/13

$348

One-way flights from Sioux Falls to St. Louis
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Thu 10/231:32 pmFSD - STL

1 stop4h 50mAmerican Airlines

Deal found 8/12

$228

Thu 10/233:19 pmFSD - STL

2 stops20h 24mFrontier

Deal found 8/12

$252

Cheapflights Fare Finder

Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 9/10

5:06 pm-11:53 pm

1 stop6h 47m

Lambert-St Louis

Sat 9/13

5:30 pm-10:12 pm

1 stop4h 42m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 9/10

5:00 am-10:37 am

1 stop5h 37m

Lambert-St Louis

Sat 9/13

6:00 am-12:11 pm

1 stop6h 11m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 1/16

5:15 am-8:54 am

1 stop3h 39m

Lambert-St Louis

Sun 1/18

6:30 am-12:35 pm

1 stop6h 05m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 8/29

5:00 am-8:36 am

1 stop3h 36m

Lambert-St Louis

Tue 9/2

5:30 pm-11:46 pm

1 stop6h 16m

$299

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 9/10

1:19 pm-8:15 pm

1 stop6h 56m

Lambert-St Louis

Sat 9/13

6:29 am-6:12 pm

2 stops11h 43m

$327

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 12/3

5:32 am-11:06 am

1 stop5h 34m

Lambert-St Louis

Sun 12/7

4:08 pm-9:00 pm

1 stop4h 52m

$334

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 10/24

5:05 pm-11:18 pm

1 stop6h 13m

Lambert-St Louis

Sun 10/26

7:01 am-12:47 pm

1 stop5h 46m

$334

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 8/29

6:03 pm-11:51 pm

1 stop5h 48m

Lambert-St Louis

Sun 9/7

7:16 am-12:39 pm

1 stop5h 23m

$343

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 9/10

2:08 pm-8:46 pm

1 stop6h 38m

Lambert-St Louis

Fri 9/12

5:15 am-10:41 am

1 stop5h 26m

$348

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 1/16

12:27 pm-11:32 pm

2 stops11h 05m

Lambert-St Louis

Sun 1/18

5:57 am-11:35 am

1 stop5h 38m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 12 results

Best time to book a flight from Sioux Falls to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to St. Louis

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $311). Flying from Sioux Falls to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to STL?

It’s typically best to fly out from Sioux Falls to St. Louis in the evening. Doing so could potentially save you 43% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Sioux Falls to St. Louis?

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?
Our cheapest airline available from Sioux Falls to St. Louis is Delta. Our recent data shows that you can find tickets from as low as $228 on this airline. Additional options worth looking into are United Airlines and American Airlines, starting at $241 and $253 round-trip. Delta is currently priced 32% below the average price you’ll pay for this route.
Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?
Yes. In addition to deals on Sioux Falls to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Sioux Falls to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to St. Louis.
Can I find deals for business class flights from Sioux Falls to St. Louis?
Yes. Cheapflights offers flight deals from Sioux Falls to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Sioux Falls to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $311). Flying from Sioux Falls to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Sioux Falls to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$228	Average$293	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$241	Average$378	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$253	Average$308	FlexibilityNo cancel fee	On-time71%

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$228+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Sioux Falls to St. Louis with Cheapflights

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Cheap flight deals from Sioux Falls to St. Louis

Round-trip from

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Popular in

Cheapest in

Average price

Find flight deals from Sioux Falls to St. Louis

Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.

Best time to book a flight from Sioux Falls to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to St. Louis

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

What is the cheapest time of day to fly from FSD to STL?

Find hourly flight availability from Sioux Falls to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

How much does it cost to fly round-trip from Sioux Falls to St. Louis?

Reviews of airlines servicing St. Louis

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Sioux Falls to St. Louis round-trip?

Can I find deals for flights from Sioux Falls to St. Louis that include hotel bookings?

How can I find direct flights from Sioux Falls to St. Louis?

Can I find deals for business class flights from Sioux Falls to St. Louis?

What is the cheapest month to book a flight from Sioux Falls to St. Louis?

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Alternative routes for Sioux Falls to St. Louis

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Top 3 airlines flying from Sioux Falls to St. Louis

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Cheapest flights from Sioux Falls to St. Louis
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.