$138+ Cheap flights from Sioux Falls to St. Louis (FSD - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Apr 26 — May 31
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Sioux Falls to St. LouisExplore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
Explore the most affordable flight options available from Sioux Falls to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Sat 6/65:41 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 3/27![United Airlines logo]()
$295
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:40 am
FSD
- STL
1 stop4h 27m
United Airlines
Wed 7/155:33 pm
STL
- FSD
1 stop4h 34m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:17 pm
FSD
- STL
1 stop7h 00m
American Airlines
Mon 4/135:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 3/24![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:43 am
FSD
- STL
1 stop5h 36m
American Airlines
Sun 12/66:00 am
STL
- FSD
1 stop4h 11m
American Airlines
Deal found 3/25![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/125:20 am
STL
- FSD
1 stop7h 37m
American Airlines
Deal found 3/24![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/197:12 am
STL
- FSD
1 stop5h 45m
American Airlines
Deal found 3/26![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:21 pm
FSD
- STL
1 stop5h 37m
American Airlines
Fri 4/107:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 3/23![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Sun 7/58:35 pm
STL
- FSD
1 stop4h 31m
United Airlines
Deal found 3/26![United Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:29 pm
FSD
- STL
1 stop26h 54m
Frontier
Thu 6/48:08 pm
STL
- FSD
1 stop19h 36m
Frontier
Deal found 3/27![Frontier logo]()
$356
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:39 am
FSD
- STL
1 stop4h 43m
United Airlines
Sun 4/511:15 am
STL
- FSD
1 stop6h 29m
United Airlines
Deal found 3/24![United Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
FSD
- STL
1 stop4h 48m
United Airlines
Wed 5/68:30 pm
STL
- FSD
1 stop4h 19m
United Airlines
Deal found 3/22![United Airlines logo]()
$361
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:29 pm
FSD
- STL
1 stop26h 54m
Multiple Airlines
Fri 6/58:08 pm
STL
- FSD
2 stops15h 58m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$367
Best flights from Sioux Falls to St. LouisDiscover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
Discover carefully curated flight deals from Sioux Falls to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:40 am
FSD
- STL
1 stop4h 31m
United Airlines
Sat 6/65:41 pm
STL
- FSD
1 stop4h 26m
United Airlines
Deal found 3/27![United Airlines logo]()
$295
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/125:20 am
STL
- FSD
1 stop7h 37m
American Airlines
Deal found 3/24![American Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:29 pm
FSD
- STL
1 stop26h 54m
Frontier
Thu 6/48:08 pm
STL
- FSD
1 stop19h 36m
Frontier
Deal found 3/27![Frontier logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:29 pm
FSD
- STL
1 stop26h 54m
Multiple Airlines
Fri 6/58:08 pm
STL
- FSD
2 stops15h 58m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/117:40 am
FSD
- STL
1 stop4h 27m
United Airlines
Wed 7/155:33 pm
STL
- FSD
1 stop4h 34m
United Airlines
Deal found 3/25![United Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:53 pm
FSD
- STL
1 stop4h 18m
United Airlines
Tue 4/147:45 am
STL
- FSD
1 stop6h 49m
United Airlines
Deal found 3/26![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/203:17 pm
FSD
- STL
1 stop7h 00m
American Airlines
Mon 4/277:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 3/23![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:05 pm
FSD
- STL
1 stop6h 52m
United Airlines
Sun 7/58:35 pm
STL
- FSD
1 stop4h 31m
United Airlines
Deal found 3/26![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:00 am
FSD
- STL
1 stop4h 48m
United Airlines
Wed 5/68:30 pm
STL
- FSD
1 stop4h 19m
United Airlines
Deal found 3/22![United Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:35 pm
FSD
- STL
1 stop6h 23m
American Airlines
Fri 6/57:52 pm
STL
- FSD
1 stop15h 45m
American Airlines
Deal found 3/27![American Airlines logo]()
$517
Last-minute flights from Sioux Falls to St. LouisDiscover last-minute flight deals from Sioux Falls to St. Louis. Data last updated March 27, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to St. Louis. Data last updated March 27, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:50 am
FSD
- STL
1 stop6h 53m
American Airlines
Sun 3/298:00 am
STL
- FSD
1 stop5h 36m
American Airlines
Deal found 3/25![American Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/261:38 pm
FSD
- STL
1 stop7h 03m
United Airlines
Sun 3/296:30 am
STL
- FSD
1 stop4h 12m
United Airlines
Deal found 3/26![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:50 am
FSD
- STL
1 stop7h 00m
American Airlines
Sun 3/297:00 am
STL
- FSD
1 stop5h 41m
American Airlines
Deal found 3/26![American Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:39 am
FSD
- STL
1 stop4h 43m
United Airlines
Sun 4/511:15 am
STL
- FSD
1 stop6h 29m
United Airlines
Deal found 3/24![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:21 pm
FSD
- STL
1 stop5h 37m
American Airlines
Fri 4/107:05 am
STL
- FSD
1 stop4h 54m
American Airlines
Deal found 3/23![American Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:21 pm
FSD
- STL
1 stop14h 27m
Multiple Airlines
Fri 4/109:50 am
STL
- FSD
2 stops7h 58m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:42 pm
FSD
- STL
1 stop4h 23m
American Airlines
Fri 4/108:03 pm
STL
- FSD
1 stop15h 56m
American Airlines
Deal found 3/22![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:17 pm
FSD
- STL
1 stop7h 00m
American Airlines
Mon 4/135:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 3/24![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/125:20 am
STL
- FSD
1 stop7h 37m
American Airlines
Deal found 3/24![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:43 pm
FSD
- STL
2 stops7h 30m
United Airlines
Mon 4/136:05 pm
STL
- FSD
1 stop5h 39m
United Airlines
Deal found 3/24![United Airlines logo]()
$652
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/197:12 am
STL
- FSD
1 stop5h 45m
American Airlines
Deal found 3/26![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/195:20 am
STL
- FSD
1 stop7h 37m
American Airlines
Deal found 3/25![American Airlines logo]()
$374
One-way flights from Sioux Falls to St. LouisSearch for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
Search for one-way flight options from Sioux Falls to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:38 pm
FSD
- STL
2 stops23h 58m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:35 pm
FSD
- STL
2 stops43h 13m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$242
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:53 pm
FSD
- STL
1 stop4h 18m
United Airlines
Deal found 3/26![United Airlines logo]()
$268
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:00 am
FSD
- STL
1 stop3h 48m
Delta
Deal found 3/25![Delta logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/247:02 pm
FSD
- STL
3 stops23h 34m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:42 pm
FSD
- STL
1 stop4h 23m
American Airlines
Deal found 3/25![American Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:07 am
FSD
- STL
3 stops37h 51m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:43 pm
FSD
- STL
2 stops7h 30m
United Airlines
Deal found 3/24![United Airlines logo]()
$458
Find flight deals from Sioux Falls to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Sioux Falls (FSD) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $295 (United Airlines) |
One-way from | $138 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $362 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Sioux Falls to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 6/5
7:40 am-12:11 pm
1 stop4h 31m
Lambert-St Louis
Sat 6/6
5:41 pm-10:07 pm
1 stop4h 26m
$295
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 7/11
7:40 am-12:07 pm
1 stop4h 27m
Lambert-St Louis
Wed 7/15
5:33 pm-10:07 pm
1 stop4h 34m
$309
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 4/10
6:53 pm-11:11 pm
1 stop4h 18m
Lambert-St Louis
Tue 4/14
7:45 am-2:34 pm
1 stop6h 49m
$319
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 4/9
7:39 pm-11:46 pm
1 stop4h 07m
Lambert-St Louis
Sun 4/12
5:20 am-12:57 pm
1 stop7h 37m
$333
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 7/3
5:05 pm-11:57 pm
1 stop6h 52m
Lambert-St Louis
Sun 7/5
8:35 pm-1:06 am
1 stop4h 31m
$348
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/1
4:29 pm-7:23 pm
1 stop26h 54m
Lambert-St Louis
Thu 6/4
8:08 pm-3:44 pm
1 stop19h 36m
$356
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 5/2
6:00 am-10:48 am
1 stop4h 48m
Lambert-St Louis
Wed 5/6
8:30 pm-12:49 am
1 stop4h 19m
$361
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/1
4:29 pm-7:23 pm
1 stop26h 54m
Lambert-St Louis
Fri 6/5
8:08 pm-12:06 pm
2 stops15h 58m
$367
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 4/20
3:17 pm-10:17 pm
1 stop7h 00m
Lambert-St Louis
Mon 4/27
7:05 am-11:59 am
1 stop4h 54m
$374
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Mon 6/1
5:35 pm-11:58 pm
1 stop6h 23m
Lambert-St Louis
Fri 6/5
7:52 pm-11:37 am
1 stop15h 45m
$517
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Sioux Falls to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Sioux Falls to St. Louis in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Sioux Falls-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Sioux Falls-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Sioux Falls-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Sioux Falls-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Sioux Falls-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Sioux Falls to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Sioux Falls with our price prediction graph.
FSD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to St. Louis
Prices
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What is the cheapest month to book a flight from Sioux Falls to St. Louis?
Currently, April is the cheapest month in which you can book a flight from Sioux Falls to St. Louis (average of $228). Flying from Sioux Falls to St. Louis in November is currently the most expensive (average of $418). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to St. Louis?
What’s the top layover airport for flights from Sioux Falls to St. Louis?
Share of 1-stop round-trip flights from Sioux Falls to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from Sioux Falls to St. Louis on Cheapflights.
What’s the cheapest layover airport for flights from Sioux Falls to St. Louis?
Average round-trip fare for 1-stop flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $278.
What’s the fastest layover option from Sioux Falls to St. Louis?
Shortest average travel time for 1-stop one-way flights from Sioux Falls to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 4h 24m.
Which airport typically offers the quickest layover for flights from Sioux Falls to St. Louis?
Average layover duration for 1-stop one-way flights from Sioux Falls to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Denver (DEN) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated March 27, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Boarding
8.1
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Sioux Falls and St. Louis flights
Browse other Sioux Falls and St. Louis flight options. Last updated on March 27, 2026.
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Top 3 airlines flying from Sioux Falls to St. Louis
Discover the top 3 airlines that operate flights from Sioux Falls to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$228 | Average$334 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$289 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$309 | FlexibilityNo cancel fee | On-time69% |