$111+ Cheap flights from Portland to St. Louis (PDX - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
Jun 19 — Jun 261
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in November or January, booked 81 days in advance, depart on a Wednesday or Tuesday and return on a Tuesday
Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 20, 2026.
This CheapOair deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:42 pm
PDX
- STL
1 stop15h 24m
Frontier
Wed 6/177:46 pm
STL
- PDX
1 stop26h 01m
Frontier
Deal found 5/17![Frontier logo]()
$299
This CheapOair deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:59 pm
PDX
- STL
1 stop17h 08m
Frontier
Tue 7/78:08 pm
STL
- PDX
1 stop22h 23m
Frontier
Deal found 5/16![Frontier logo]()
$300
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:45 pm
PDX
- STL
1 stop9h 20m
Southwest
Sat 8/298:30 am
STL
- PDX
Nonstop4h 10m
Southwest
Deal found 5/17![Southwest logo]()
$309
This Travelocity deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:34 pm
PDX
- STL
1 stop12h 17m
Multiple Airlines
Tue 9/226:08 pm
STL
- PDX
Nonstop4h 12m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/1611:30 pm
PDX
- STL
1 stop7h 45m
Southwest
Fri 8/215:45 am
STL
- PDX
1 stop6h 15m
Southwest
Deal found 5/16![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:00 pm
PDX
- STL
1 stop6h 23m
Delta
Sat 6/276:21 am
STL
- PDX
1 stop8h 19m
Delta
Deal found 5/15![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:30 pm
PDX
- STL
1 stop9h 00m
Southwest
Sun 8/236:10 am
STL
- PDX
1 stop6h 25m
Southwest
Deal found 5/18![Southwest logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:38 pm
PDX
- STL
2 stops40h 14m
Multiple Airlines
Tue 6/238:08 pm
STL
- PDX
1 stop22h 27m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$324
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:15 am
PDX
- STL
1 stop6h 56m
Multiple Airlines
Sun 6/75:33 pm
STL
- PDX
Nonstop4h 17m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:42 pm
PDX
- STL
1 stop23h 41m
Frontier
Thu 9/108:10 pm
STL
- PDX
1 stop22h 25m
Frontier
Deal found 5/20![Frontier logo]()
$329
This Orbitz deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:34 pm
PDX
- STL
1 stop12h 17m
Multiple Airlines
Fri 9/256:08 pm
STL
- PDX
Nonstop4h 12m
Multiple Airlines
Deal found 5/19![Multiple Airlines logo]()
$330
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 20, 2026.
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:05 pm
PDX
- STL
1 stop5h 31m
Delta
Mon 11/95:30 pm
STL
- PDX
1 stop8h 17m
Delta
Deal found 5/16![Delta logo]()
$319
This Alaska Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:16 am
PDX
- STL
Nonstop3h 54m
Alaska Airlines
Wed 9/236:08 pm
STL
- PDX
Nonstop4h 12m
Alaska Airlines
Deal found 5/18![Alaska Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
PDX
- STL
1 stop5h 50m
Southwest
Fri 10/97:45 am
STL
- PDX
1 stop9h 00m
Southwest
Deal found 5/19![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:27 pm
PDX
- STL
1 stop6h 23m
United Airlines
Mon 6/87:23 pm
STL
- PDX
1 stop7h 27m
United Airlines
Deal found 5/15![United Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:14 pm
PDX
- STL
1 stop5h 27m
Delta
Mon 7/136:21 am
STL
- PDX
1 stop6h 20m
Delta
Deal found 5/17![Delta logo]()
$319
This Alaska Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:49 am
PDX
- STL
Nonstop3h 48m
Alaska Airlines
Sat 8/296:08 pm
STL
- PDX
Nonstop4h 12m
Alaska Airlines
Deal found 5/20![Alaska Airlines logo]()
$348
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/53:10 pm
PDX
- STL
1 stop6h 08m
Delta
Sat 11/76:30 am
STL
- PDX
1 stop6h 06m
Delta
Deal found 5/16![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:50 am
PDX
- STL
2 stops8h 55m
Southwest
Thu 9/246:05 am
STL
- PDX
1 stop10h 55m
Southwest
Deal found 5/17![Southwest logo]()
$363
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:15 pm
PDX
- STL
1 stop5h 42m
United Airlines
Sun 6/146:00 am
STL
- PDX
1 stop7h 38m
United Airlines
Deal found 5/19![United Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:40 am
PDX
- STL
1 stop7h 25m
Southwest
Sat 6/65:35 pm
STL
- PDX
Nonstop4h 05m
Southwest
Deal found 5/19![Southwest logo]()
$367
This Southwest deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:15 am
PDX
- STL
2 stops8h 30m
Southwest
Fri 7/176:30 pm
STL
- PDX
1 stop7h 25m
Southwest
Deal found 5/15![Southwest logo]()
$419
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated May 20, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated May 20, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:15 am
PDX
- STL
1 stop6h 56m
Frontier
Mon 6/88:08 pm
STL
- PDX
1 stop22h 27m
Frontier
Deal found 5/15![Frontier logo]()
$339
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Wed 6/36:51 pm
STL
- PDX
1 stop17h 29m
Frontier
Deal found 5/18![Frontier logo]()
$340
This Orbitz deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:15 am
PDX
- STL
1 stop6h 56m
Multiple Airlines
Tue 6/165:37 pm
STL
- PDX
Nonstop4h 10m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$345
This Alaska Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Mon 6/295:37 pm
STL
- PDX
Nonstop4h 10m
Alaska Airlines
Deal found 5/15![Alaska Airlines logo]()
$319
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:15 am
PDX
- STL
1 stop6h 56m
Multiple Airlines
Sun 6/75:33 pm
STL
- PDX
Nonstop4h 17m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$325
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:15 am
PDX
- STL
1 stop6h 56m
Frontier
Mon 6/88:08 pm
STL
- PDX
1 stop22h 27m
Frontier
Deal found 5/18![Frontier logo]()
$334
This Alaska Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Mon 6/295:37 pm
STL
- PDX
Nonstop4h 10m
Alaska Airlines
Deal found 5/15![Alaska Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:00 pm
PDX
- STL
1 stop6h 23m
Delta
Sat 6/276:21 am
STL
- PDX
1 stop8h 19m
Delta
Deal found 5/15![Delta logo]()
$318
This CheapOair deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:42 pm
PDX
- STL
1 stop15h 24m
Frontier
Wed 6/177:46 pm
STL
- PDX
1 stop26h 01m
Frontier
Deal found 5/17![Frontier logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:38 pm
PDX
- STL
2 stops40h 14m
Multiple Airlines
Tue 6/238:08 pm
STL
- PDX
1 stop22h 27m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$324
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:26 pm
PDX
- STL
1 stop28h 27m
Frontier
Wed 6/177:46 pm
STL
- PDX
1 stop26h 01m
Frontier
Deal found 5/18![Frontier logo]()
$344
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated May 20, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 5/18![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:38 pm
PDX
- STL
2 stops40h 14m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$129
This CheapOair deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:16 pm
PDX
- STL
1 stop24h 07m
Frontier
Deal found 5/18![Frontier logo]()
$146
This CheapOair deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:16 am
PDX
- STL
Nonstop3h 54m
Alaska Airlines
Deal found 5/17![Alaska Airlines logo]()
$150
This Trip.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 5/16![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:42 pm
PDX
- STL
1 stop23h 41m
Frontier
Deal found 5/19![Frontier logo]()
$158
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/611:43 pm
PDX
- STL
1 stop7h 07m
American Airlines
Deal found 5/16![American Airlines logo]()
$159
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:24 pm
PDX
- STL
1 stop5h 19m
Delta
Deal found 5/17![Delta logo]()
$160
This Trip.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:42 pm
PDX
- STL
1 stop20h 09m
Frontier
Deal found 5/16![Frontier logo]()
$161
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (CheapOair) |
One-way from | $111 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $400 |
Good round-trip deal | $404 or less |
Good one-way deal | $169 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Fri 11/6
5:05 pm-12:36 am
1 stop5h 31m
Lambert-St Louis
Mon 11/9
5:30 pm-11:47 pm
1 stop8h 17m
$319
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Fri 9/18
11:16 am-5:10 pm
Nonstop3h 54m
Lambert-St Louis
Wed 9/23
6:08 pm-8:20 pm
Nonstop4h 12m
$319
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 10/6
6:00 am-1:50 pm
1 stop5h 50m
Lambert-St Louis
Fri 10/9
7:45 am-2:45 pm
1 stop9h 00m
$319
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 7/9
5:14 pm-12:41 am
1 stop5h 27m
Lambert-St Louis
Mon 7/13
6:21 am-10:41 am
1 stop6h 20m
$319
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 11/5
3:10 pm-11:18 pm
1 stop6h 08m
Lambert-St Louis
Sat 11/7
6:30 am-10:36 am
1 stop6h 06m
$319
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Sat 5/30
2:27 pm-10:50 pm
1 stop6h 23m
Lambert-St Louis
Mon 6/8
7:23 pm-12:50 am
1 stop7h 27m
$348
Quickest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Mon 8/17
10:49 am-4:37 pm
Nonstop3h 48m
Lambert-St Louis
Sat 8/29
6:08 pm-8:20 pm
Nonstop4h 12m
$348
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 9/22
7:50 am-6:45 pm
2 stops8h 55m
Lambert-St Louis
Thu 9/24
6:05 am-3:00 pm
1 stop10h 55m
$363
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 6/2
5:40 am-3:05 pm
1 stop7h 25m
Lambert-St Louis
Sat 6/6
5:35 pm-7:40 pm
Nonstop4h 05m
$367
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 6/11
4:15 pm-11:57 pm
1 stop5h 42m
Lambert-St Louis
Sun 6/14
6:00 am-11:38 am
1 stop7h 38m
$382
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PDX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
How far ahead should I book a flight from Portland to St. Louis?
The best time to book flights from Portland to St. Louis is 80 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, November is the cheapest month in which you can book a flight from Portland to St. Louis (average of $300). Flying from Portland to St. Louis in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PDX to STL?
Find hourly flight availability from Portland to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 20, 2026.
When flying from Portland to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated May 20, 2026.
See what other customers who have flown with Alaska Airlines,Southwest, andDelta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Crew
8.5
Entertainment
7.0
Overall
7.9
Comfort
7.8
Boarding
8.1
Food
7.0
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on May 20, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on May 20, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 20, 2026.
Top 6 airlines flying from Portland to St. Louis
Discover the top 6 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$182 | Average$377 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$368 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$228 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$425 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$392 | FlexibilityNo cancel fee | On-time69% |