$80+ Cheap flights from Portland to St. Louis (PDX - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
Apr 25 — May 21
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in November or September, booked 81 days in advance, depart on a Wednesday or Monday and return on a Tuesday
Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:48 am
PDX
- STL
1 stop5h 33m
Frontier
Sat 4/188:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/26![Frontier logo]()
$216
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
PDX
- STL
1 stop7h 10m
Southwest
Wed 4/295:30 am
STL
- PDX
2 stops10h 20m
Southwest
Deal found 3/25![Southwest logo]()
$218
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- STL
1 stop28h 43m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/23![Frontier logo]()
$221
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:15 pm
PDX
- STL
1 stop8h 27m
Delta
Sat 5/25:00 pm
STL
- PDX
1 stop7h 45m
Delta
Deal found 3/26![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:55 pm
PDX
- STL
1 stop7h 35m
Southwest
Tue 4/281:45 pm
STL
- PDX
2 stops9h 00m
Southwest
Deal found 3/26![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:50 pm
PDX
- STL
1 stop7h 00m
Southwest
Tue 5/125:30 am
STL
- PDX
2 stops10h 20m
Southwest
Deal found 3/25![Southwest logo]()
$230
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
PDX
- STL
1 stop5h 44m
Frontier
Mon 4/278:17 pm
STL
- PDX
1 stop17h 35m
Frontier
Deal found 3/23![Frontier logo]()
$236
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:45 pm
PDX
- STL
1 stop8h 02m
United Airlines
Wed 5/275:41 pm
STL
- PDX
1 stop6h 49m
United Airlines
Deal found 3/26![United Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:38 pm
PDX
- STL
2 stops19h 52m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/26![Frontier logo]()
$243
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:16 pm
PDX
- STL
1 stop6h 30m
American Airlines
Tue 5/55:21 pm
STL
- PDX
1 stop8h 36m
American Airlines
Deal found 3/25![American Airlines logo]()
$244
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
PDX
- STL
1 stop5h 38m
Delta
Tue 4/146:45 pm
STL
- PDX
1 stop7h 08m
Delta
Deal found 3/25![Delta logo]()
$245
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:59 pm
PDX
- STL
1 stop6h 26m
United Airlines
Fri 4/176:05 pm
STL
- PDX
1 stop6h 49m
United Airlines
Deal found 3/25![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:55 pm
PDX
- STL
1 stop7h 35m
Southwest
Fri 4/171:55 pm
STL
- PDX
2 stops9h 45m
Southwest
Deal found 3/25![Southwest logo]()
$295
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/213:10 pm
PDX
- STL
1 stop6h 11m
Delta
Wed 5/277:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 3/23![Delta logo]()
$309
This Alaska Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Wed 5/275:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 3/25![Alaska Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:41 pm
PDX
- STL
1 stop6h 04m
United Airlines
Tue 5/54:44 pm
STL
- PDX
1 stop8h 15m
United Airlines
Deal found 3/21![United Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:15 am
PDX
- STL
2 stops8h 30m
Southwest
Wed 6/105:55 pm
STL
- PDX
1 stop7h 35m
Southwest
Deal found 3/24![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:05 pm
PDX
- STL
1 stop5h 25m
Delta
Tue 5/267:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 3/23![Delta logo]()
$322
This Alaska Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:52 pm
PDX
- STL
1 stop8h 07m
Alaska Airlines
Sat 5/27:00 am
STL
- PDX
1 stop7h 52m
Alaska Airlines
Deal found 3/22![Alaska Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/21:15 pm
PDX
- STL
1 stop6h 00m
Southwest
Tue 5/55:30 am
STL
- PDX
2 stops10h 20m
Southwest
Deal found 3/21![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:32 pm
PDX
- STL
2 stops12h 16m
Delta
Wed 4/221:46 pm
STL
- PDX
1 stop9h 56m
Delta
Deal found 3/25![Delta logo]()
$325
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated March 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:45 am
PDX
- STL
1 stop5h 38m
Delta
Tue 4/146:45 pm
STL
- PDX
1 stop7h 08m
Delta
Deal found 3/25![Delta logo]()
$245
This CheapOair deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:48 am
PDX
- STL
1 stop5h 33m
Frontier
Sat 4/188:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/26![Frontier logo]()
$216
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:15 pm
PDX
- STL
1 stop8h 33m
Delta
Wed 4/221:46 pm
STL
- PDX
1 stop9h 56m
Delta
Deal found 3/25![Delta logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:48 am
PDX
- STL
1 stop29h 44m
Frontier
Mon 4/209:55 pm
STL
- PDX
2 stops15h 57m
Frontier
Deal found 3/25![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:55 pm
PDX
- STL
1 stop7h 35m
Southwest
Tue 4/281:45 pm
STL
- PDX
2 stops9h 00m
Southwest
Deal found 3/26![Southwest logo]()
$225
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:48 am
PDX
- STL
1 stop5h 44m
Frontier
Mon 4/278:17 pm
STL
- PDX
1 stop17h 35m
Frontier
Deal found 3/23![Frontier logo]()
$236
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:15 pm
PDX
- STL
1 stop8h 27m
Delta
Sat 5/25:00 pm
STL
- PDX
1 stop7h 45m
Delta
Deal found 3/26![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:55 pm
PDX
- STL
1 stop7h 35m
Southwest
Fri 4/241:45 pm
STL
- PDX
1 stop12h 25m
Southwest
Deal found 3/22![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:55 pm
PDX
- STL
1 stop7h 10m
Southwest
Wed 4/295:30 am
STL
- PDX
2 stops10h 20m
Southwest
Deal found 3/25![Southwest logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:38 pm
PDX
- STL
2 stops19h 52m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/26![Frontier logo]()
$243
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- STL
1 stop28h 43m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 3/23![Frontier logo]()
$221
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Travelocity deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:48 am
PDX
- STL
1 stop5h 33m
Frontier
Deal found 3/24![Frontier logo]()
$80
This Expedia deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:46 pm
PDX
- STL
1 stop21h 37m
Frontier
Deal found 3/26![Frontier logo]()
$86
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Deal found 3/25![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:28 pm
PDX
- STL
1 stop28h 53m
Frontier
Deal found 3/25![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/112:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 3/26![Frontier logo]()
$98
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:05 pm
PDX
- STL
1 stop5h 25m
Delta
Deal found 3/26![Delta logo]()
$103
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:15 am
PDX
- STL
1 stop6h 06m
Frontier
Deal found 3/25![Frontier logo]()
$105
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:30 am
PDX
- STL
2 stops9h 25m
Southwest
Deal found 3/26![Southwest logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:48 am
PDX
- STL
1 stop29h 33m
Frontier
Deal found 3/25![Frontier logo]()
$114
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:30 am
PDX
- STL
2 stops9h 25m
Southwest
Deal found 3/26![Southwest logo]()
$116
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Deal found 3/25![Frontier logo]()
$117
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $216 (CheapOair) |
One-way from | $80 (Travelocity) |
Popular in | March |
Cheapest in | November |
Average price | $480 |
Good round-trip deal | $213 or less |
Good one-way deal | $163 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 4/14
11:59 pm-8:25 am
1 stop6h 26m
Lambert-St Louis
Fri 4/17
6:05 pm-10:54 pm
1 stop6h 49m
$264
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Sat 5/2
2:41 pm-10:45 pm
1 stop6h 04m
Lambert-St Louis
Tue 5/5
4:44 pm-10:59 pm
1 stop8h 15m
$277
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Mon 4/13
11:55 pm-9:30 am
1 stop7h 35m
Lambert-St Louis
Fri 4/17
1:55 pm-9:40 pm
2 stops9h 45m
$295
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 5/21
3:10 pm-11:21 pm
1 stop6h 11m
Lambert-St Louis
Wed 5/27
7:59 pm-11:44 pm
1 stop5h 45m
$309
Quickest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Wed 5/20
10:37 am-4:37 pm
Nonstop4h 00m
Lambert-St Louis
Wed 5/27
5:33 pm-7:50 pm
Nonstop4h 17m
$309
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Wed 6/3
11:15 am-9:45 pm
2 stops8h 30m
Lambert-St Louis
Wed 6/10
5:55 pm-11:30 pm
1 stop7h 35m
$311
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Sat 5/2
1:15 pm-9:15 pm
1 stop6h 00m
Lambert-St Louis
Tue 5/5
5:30 am-1:50 pm
2 stops10h 20m
$314
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Fri 5/22
5:05 pm-12:30 am
1 stop5h 25m
Lambert-St Louis
Tue 5/26
7:59 pm-11:44 pm
1 stop5h 45m
$322
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Fri 4/17
7:32 pm-9:48 am
2 stops12h 16m
Lambert-St Louis
Wed 4/22
1:46 pm-9:42 pm
1 stop9h 56m
$325
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 4/28
1:52 pm-11:59 pm
1 stop8h 07m
Lambert-St Louis
Sat 5/2
7:00 am-12:52 pm
1 stop7h 52m
$332
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PDX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
How far ahead should I book a flight from Portland to St. Louis?
Use this chart to determine the optimal time to book a round-trip flight from Portland to St. Louis. Price data was last updated on March 13, 2026.
The best time to book flights from Portland to St. Louis is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Portland to St. Louis (average of $165). Flying from Portland to St. Louis in February is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated March 26, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on March 26, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on March 26, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 26, 2026.
Top 6 airlines flying from Portland to St. Louis
Discover the top 6 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$184 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$324 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$226 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$366 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$393 | FlexibilityNo cancel fee | On-time63% |