How long is the flight from Portland to St. Louis?

For as low as $249, Frontier can have you in St. Louis from Portland in 5h 34m. There are 1702 mi between Portland and St. Louis. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Portland to St. Louis round-trip?

Currently priced at $139, Frontier will fly you from Portland to St. Louis and back. In addition to Frontier, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $193 and $226, respectively. Users have found that Frontier is 62% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Portland to St. Louis one-way?

To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $86. Delta flights start at $113 while deals on American Airlines start at $113 one-way.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What are the most popular airlines that fly from Portland to St. Louis?

Before booking your flight from Portland to St. Louis check out the most popular airlines for this route: Delta, Southwest or United Airlines.

Where are the most common layover locations when flying from Portland to St. Louis?

Portland to St. Louis flights have a layover in Denver most of the time.

Where are the least popular layover locations for Portland to St. Louis flights?

Of the flights from Portland to St. Louis that have layovers, the fewest flights stop in Salt Lake City.

What are some popular things to do or see while on a layover in Denver?

If you're on a layover in Denver and looking for things to do, consider visiting Coors Field, 16th Street Mall, or Paramount Theatre. Coors Field, 16th Street Mall, and Paramount Theatre are located about 18.4 mi, 18.7 mi, and 18.6 mi, respectively from Denver Intl. Travelers can rent a car at Denver Intl for an average daily rate of $44 to make sightseeing during their layover a little easier.

What is the cheapest time of day to fly from PDX to STL?

When flying from Portland to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Most accurate provider : When it comes to deals on Portland-St. Louis flights, users find the pricing of CheapOair to be most consistent on Cheapflights vs. CheapOair Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. CheapOair >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland-St. Louis flights, Cheapflights users trust CheapOair the most. CheapOair has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.

Can I find deals for business class flights from Portland to St. Louis?

Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$68+ Flights from Portland to St. Louis

Q: How much does it cost to fly round-trip from Portland to St. Louis?

Airfare is below average for this route at the moment. Portland to St. Louis flights typically cost between $248 and $377 in January. The cheapest round-trip price found within the last 3 days was $193 on Frontier (Jan 29-Feb 1).

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Find cheap flights from Portland to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in January or November, booked 76 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Portland to St. Louis

Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 28, 2025.

lun. 12/2912:00 pmPDX - STL

1 stop6h 41mDelta

vie. 1/22:18 pmSTL - PDX

1 stop5h 56mDelta

Deal found 12/26

$548

dom. 12/285:00 amPDX - STL

2 stops9h 27mUnited Airlines

dom. 1/410:30 amSTL - PDX

1 stop11h 13mUnited Airlines

Deal found 12/27

$553

lun. 12/292:45 pmPDX - STL

1 stop5h 37mUnited Airlines

mié. 12/311:05 pmSTL - PDX

1 stop9h 43mUnited Airlines

Deal found 12/26

$593

lun. 12/292:45 pmPDX - STL

1 stop5h 37mUnited Airlines

vie. 1/26:30 amSTL - PDX

2 stops13h 01mUnited Airlines

Deal found 12/26

$643

lun. 12/2911:59 pmPDX - STL

1 stop6h 57mAmerican Airlines

mié. 12/313:30 pmSTL - PDX

1 stop8h 29mAmerican Airlines

Deal found 12/25

$750

dom. 12/287:30 pmPDX - STL

2 stops11h 54mDelta

vie. 1/23:43 pmSTL - PDX

1 stop6h 51mDelta

Deal found 12/27

$814

vie. 12/2611:00 pmPDX - STL

1 stop7h 35mAlaska Airlines

lun. 12/292:43 pmSTL - PDX

1 stop9h 55mAlaska Airlines

Deal found 12/26

$826

dom. 12/285:10 amPDX - STL

2 stops8h 05mSouthwest

dom. 1/49:50 amSTL - PDX

2 stops7h 35mSouthwest

Deal found 12/27

$1,001

Best flights from Portland to St. Louis
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 28, 2025.

jue. 1/2911:28 amPDX - STL

1 stop7h 38mFrontier

dom. 2/19:32 pmSTL - PDX

1 stop15h 46mFrontier

Deal found 12/26

$193

mié. 3/411:46 amPDX - STL

1 stop8h 23mAmerican Airlines

lun. 3/911:47 amSTL - PDX

1 stop9h 29mAmerican Airlines

Deal found 12/26

$249

vie. 1/231:24 pmPDX - STL

1 stop5h 34mUnited Airlines

vie. 1/306:45 amSTL - PDX

1 stop10h 01mUnited Airlines

Deal found 12/27

$249

mié. 3/46:00 amPDX - STL

1 stop8h 45mDelta

mar. 3/106:12 pmSTL - PDX

1 stop7h 42mDelta

Deal found 12/27

$249

mar. 3/1010:35 pmPDX - STL

1 stop8h 00mAmerican Airlines

jue. 3/126:00 amSTL - PDX

1 stop6h 48mAmerican Airlines

Deal found 12/27

$249

lun. 2/912:59 pmPDX - STL

1 stop7h 01mUnited Airlines

dom. 2/156:00 pmSTL - PDX

1 stop7h 14mUnited Airlines

Deal found 12/26

$249

jue. 3/55:45 amPDX - STL

1 stop5h 47mDelta

mié. 3/111:39 pmSTL - PDX

1 stop10h 14mDelta

Deal found 12/27

$249

jue. 1/296:00 amPDX - STL

1 stop8h 14mAmerican Airlines

lun. 2/23:37 pmSTL - PDX

1 stop8h 34mAmerican Airlines

Deal found 12/26

$249

mar. 3/36:00 amPDX - STL

1 stop6h 54mDelta

mar. 3/103:05 pmSTL - PDX

1 stop8h 07mDelta

Deal found 12/27

$249

lun. 2/21:24 pmPDX - STL

1 stop5h 34mUnited Airlines

mié. 2/411:20 amSTL - PDX

1 stop9h 36mUnited Airlines

Deal found 12/27

$249

jue. 2/2611:59 pmPDX - STL

1 stop6h 53mAmerican Airlines

dom. 3/16:00 amSTL - PDX

1 stop6h 49mAmerican Airlines

Deal found 12/26

$249

sáb. 1/2410:47 amPDX - STL

1 stop6h 40mUnited Airlines

sáb. 1/3111:20 amSTL - PDX

1 stop9h 36mUnited Airlines

Deal found 12/27

$249

Last-minute flights from Portland to St. Louis
Discover last-minute flight deals from Portland to St. Louis. Data last updated diciembre 28, 2025 and is based on user searches.

vie. 1/97:00 amPDX - STL

1 stop7h 03mUnited Airlines

jue. 1/226:30 amSTL - PDX

1 stop7h 27mUnited Airlines

Deal found 12/26

$333

dom. 1/1112:10 pmPDX - STL

1 stop19h 52mFrontier

jue. 1/151:35 pmSTL - PDX

2 stops29h 49mFrontier

Deal found 12/27

$306

sáb. 1/171:24 pmPDX - STL

1 stop5h 34mUnited Airlines

mar. 1/2011:20 amSTL - PDX

2 stops11h 52mUnited Airlines

Deal found 12/26

$321

sáb. 1/175:20 amPDX - STL

1 stop5h 35mSouthwest

sáb. 1/172:45 pmSTL - PDX

1 stop7h 10mSouthwest

Deal found 12/25

$334

vie. 1/231:24 pmPDX - STL

1 stop5h 34mUnited Airlines

vie. 1/306:45 amSTL - PDX

1 stop10h 01mUnited Airlines

Deal found 12/27

$249

vie. 1/2311:10 amPDX - STL

2 stops10h 13mDelta

vie. 1/303:31 pmSTL - PDX

1 stop7h 01mDelta

Deal found 12/26

$272

sáb. 1/248:30 amPDX - STL

2 stops8h 57mUnited Airlines

sáb. 1/315:00 pmSTL - PDX

1 stop8h 06mUnited Airlines

Deal found 12/27

$254

jue. 1/2911:28 amPDX - STL

1 stop7h 38mFrontier

dom. 2/19:32 pmSTL - PDX

1 stop15h 46mFrontier

Deal found 12/26

$193

jue. 1/2911:28 amPDX - STL

1 stop7h 38mMultiple Airlines

dom. 2/19:32 pmSTL - PDX

2 stops24h 55mMultiple Airlines

Deal found 12/26

$223

vie. 1/3011:10 amPDX - STL

2 stops10h 15mDelta

lun. 2/26:40 amSTL - PDX

1 stop7h 52mDelta

Deal found 12/27

$326

vie. 1/301:24 pmPDX - STL

1 stop5h 34mUnited Airlines

lun. 2/24:15 pmSTL - PDX

2 stops10h 24mUnited Airlines

Deal found 12/26

$332

One-way flights from Portland to St. Louis
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated diciembre 28, 2025.

vie. 1/1611:59 amPDX - STL

1 stop24h 49mFrontier

Deal found 12/26

$68

dom. 1/1811:49 amPDX - STL

1 stop29h 02mFrontier

Deal found 12/27

$90

jue. 1/2911:28 amPDX - STL

1 stop7h 38mFrontier

Deal found 12/26

$91

dom. 1/1112:10 pmPDX - STL

1 stop19h 52mFrontier

Deal found 12/26

$93

lun. 3/912:52 pmPDX - STL

1 stop28h 19mFrontier

Deal found 12/27

$102

jue. 1/1511:59 amPDX - STL

1 stop28h 33mFrontier

Deal found 12/26

$103

vie. 3/612:04 pmPDX - STL

1 stop19h 45mFrontier

Deal found 12/27

$107

vie. 2/1310:18 pmPDX - STL

1 stop17h 28mFrontier

Deal found 12/27

$108

jue. 2/511:28 amPDX - STL

1 stop7h 38mFrontier

Deal found 12/26

$112

dom. 3/16:56 pmPDX - STL

1 stop22h 56mMultiple Airlines

Deal found 12/27

$113

Find flight deals from Portland to St. Louis

Most accurate provider	CheapOair 3 stars
Most trusted provider	CheapOair 3 stars
Round-trip from	$193 (Kiwi.com)
One-way from	$68 (Kiwi.com)
Popular in	March
Cheapest in	January
Average price	$459

Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.

Search Deals

From Portland to Lambert-St Louis

Search Deals

One-way flight from Portland to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

jue. 1/29

11:28 am-9:06 pm

1 stop7h 38m

Lambert-St Louis

dom. 2/1

9:32 pm-11:18 am

1 stop15h 46m

$193

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

mié. 3/4

11:46 am-10:09 pm

1 stop8h 23m

Lambert-St Louis

lun. 3/9

11:47 am-7:16 pm

1 stop9h 29m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

vie. 1/23

1:24 pm-8:58 pm

1 stop5h 34m

Lambert-St Louis

vie. 1/30

6:45 am-2:46 pm

1 stop10h 01m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

mié. 3/4

6:00 am-4:45 pm

1 stop8h 45m

Lambert-St Louis

mar. 3/10

6:12 pm-11:54 pm

1 stop7h 42m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

mar. 3/10

10:35 pm-8:35 am

1 stop8h 00m

Lambert-St Louis

jue. 3/12

6:00 am-10:48 am

1 stop6h 48m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

lun. 2/9

12:59 pm-10:00 pm

1 stop7h 01m

Lambert-St Louis

dom. 2/15

6:00 pm-11:14 pm

1 stop7h 14m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

jue. 3/5

5:45 am-1:32 pm

1 stop5h 47m

Lambert-St Louis

mié. 3/11

1:39 pm-9:53 pm

1 stop10h 14m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

jue. 1/29

6:00 am-4:14 pm

1 stop8h 14m

Lambert-St Louis

lun. 2/2

3:37 pm-10:11 pm

1 stop8h 34m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

mar. 3/3

6:00 am-2:54 pm

1 stop6h 54m

Lambert-St Louis

mar. 3/10

3:05 pm-9:12 pm

1 stop8h 07m

$249

PortlandSt. Louis

PDX - STL

PDXSTL

Portland

lun. 2/2

1:24 pm-8:58 pm

1 stop5h 34m

Lambert-St Louis

mié. 2/4

11:20 am-6:56 pm

1 stop9h 36m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Showing 1-10 of 21 results

Compare providers for flights from Portland to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
CheapOair	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars
CheapTicketsDeal	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
Cheapfaremart	Price Accuracy-	Trust Score*1 star
JustAirTicket	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of CheapOair to be most consistent on Cheapflights vs. CheapOair Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. CheapOair >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust CheapOair the most. CheapOair has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

How far ahead should I book a flight from Portland to St. Louis?

The best time to book flights from Portland to St. Louis is 76 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Portland to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Portland to St. Louis (average of $189). Flying from Portland to St. Louis in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Portland to St. Louis?

Travelers seeking maximum savings on their Portland to St. Louis flight should consider departing on Wednesday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Portland to St. Louis?

Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

Alaska Airlines

8.0

Very good

11,551 reviews

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

Southwest

8.0

Very good

4,256 reviews

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

Delta

7.9

Good

8,019 reviews

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

United Airlines

7.4

Good

9,113 reviews

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

American Airlines

7.2

Good

11,073 reviews

Alaska Airlines

8.0

Very good

11,551 reviews

Reviews

1 / 20

10.0

Excellent

Georgana,Dec 2025

ORD - PDX

Very cordial grew. Thank you. However, crying baby issues and no ear plugs available.

Related info for your journey

How long is the flight from Portland to St. Louis?
For as low as $249, Frontier can have you in St. Louis from Portland in 5h 34m. There are 1702 mi between Portland and St. Louis. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Portland to St. Louis round-trip?
Currently priced at $139, Frontier will fly you from Portland to St. Louis and back. In addition to Frontier, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $193 and $226, respectively. Users have found that Frontier is 62% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Portland to St. Louis one-way?
To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $86. Delta flights start at $113 while deals on American Airlines start at $113 one-way.
Where are the most common layover locations when flying from Portland to St. Louis?
Portland to St. Louis flights have a layover in Denver most of the time.
What are some popular things to do or see while on a layover in Denver?
If you're on a layover in Denver and looking for things to do, consider visiting Coors Field, 16th Street Mall, or Paramount Theatre. Coors Field, 16th Street Mall, and Paramount Theatre are located about 18.4 mi, 18.7 mi, and 18.6 mi, respectively from Denver Intl. Travelers can rent a car at Denver Intl for an average daily rate of $44 to make sightseeing during their layover a little easier.
Where are the least popular layover locations for Portland to St. Louis flights?
Of the flights from Portland to St. Louis that have layovers, the fewest flights stop in Salt Lake City.
Can I find deals for flights from Portland to St. Louis that include hotel bookings?
Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.
Can I find deals for business class flights from Portland to St. Louis?
Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, August is the cheapest month in which you can book a flight from Portland to St. Louis (average of $189). Flying from Portland to St. Louis in March is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Portland to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$158	Average$266	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$217	Average$374	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$226	Average$388	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$226	Average$393	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$246	Average$402	FlexibilityNo cancel fee	On-time63%
Alaska Airlines	Cheapest$262	Average$429	FlexibilityNo cancel fee	On-time75%

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$68+ Cheap flights from Portland to St. Louis (PDX - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in January or November, booked 76 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Portland to St. Louis

Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 28, 2025.

Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 28, 2025.

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Best time to book a flight from Portland to St. Louis

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Reviews of airlines servicing St. Louis

See what other customers who have flown with Alaska Airlines, Southwest, and Delta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Portland to St. Louis?

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What are the cheapest airlines to fly from Portland to St. Louis one-way?

Where are the most common layover locations when flying from Portland to St. Louis?

What are some popular things to do or see while on a layover in Denver?

Where are the least popular layover locations for Portland to St. Louis flights?

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

How can I find direct flights from Portland to St. Louis?

Can I find deals for business class flights from Portland to St. Louis?

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Alternative routes for Portland to St. Louis

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Top 6 airlines flying from Portland to St. Louis

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Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 28, 2025.