$135+ Cheap flights from Portland to St. Louis (PDX - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
Sep 26 — Oct 31
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in November or May, booked 73 days in advance, depart on a Tuesday or Friday and return on a Tuesday
Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.
This Expedia deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:00 am -
2 stops13h 59m
Tue 11/37:00 am -
2 stops11h 31m
Deal found 8/26![Alaska Airlines logo]()
$273
This Cheapflightsfares deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:49 am -
1 stop25h 35m
Sun 10/2512:16 pm -
1 stop25h 24m
Deal found 8/25![Frontier logo]()
$299
This Cheapflightsfares deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:38 pm -
1 stop28h 39m
Sun 9/1312:27 pm -
1 stop25h 27m
Deal found 8/26![Frontier logo]()
$308
This CheapOair deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:11 pm -
1 stop22h 24m
Mon 10/128:00 pm -
1 stop16h 54m
Deal found 8/25![Frontier logo]()
$309
This Alaska Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:16 am -
Nonstop3h 54m
Sat 9/266:08 pm -
Nonstop4h 12m
Deal found 8/24![Alaska Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:49 am -
1 stop29h 26m
Wed 10/216:35 pm -
2 stops43h 05m
Deal found 8/23![Frontier logo]()
$322
This CheapOair deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:40 am -
1 stop28h 10m
Wed 9/912:17 pm -
1 stop25h 19m
Deal found 8/24![Frontier logo]()
$326
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:05 pm -
1 stop7h 45m
Sat 9/268:30 am -
Nonstop4h 10m
Deal found 8/22![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:49 am -
2 stops27h 51m
Mon 10/268:00 pm -
1 stop17h 07m
Deal found 8/25![Frontier logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:02 pm -
1 stop25h 21m
Wed 11/116:44 pm -
2 stops18h 23m
Deal found 8/26![Frontier logo]()
$331
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:38 pm -
2 stops11h 45m
Wed 12/910:18 am -
2 stops13h 48m
Deal found 8/25![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:30 am -
2 stops10h 00m
Tue 11/31:55 pm -
2 stops9h 30m
Deal found 8/23![Southwest logo]()
$363
This Alaska Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:16 am -
Nonstop3h 54m
Fri 9/256:29 am -
1 stop9h 08m
Deal found 8/23![Alaska Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/811:12 pm -
1 stop8h 32m
Tue 10/137:00 pm -
1 stop6h 47m
Deal found 8/25![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:15 am -
2 stops8h 50m
Sun 11/87:15 pm -
1 stop6h 40m
Deal found 8/26![Southwest logo]()
$368
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:32 am -
2 stops9h 54m
Sun 12/67:08 am -
2 stops13h 50m
Deal found 8/25![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:00 am -
2 stops9h 10m
Mon 11/94:00 pm -
2 stops9h 20m
Deal found 8/22![Southwest logo]()
$408
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:40 am -
1 stop5h 50m
Thu 9/176:55 pm -
1 stop6h 45m
Deal found 8/24![Delta logo]()
$398
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:33 pm -
2 stops13h 06m
Mon 11/167:00 pm -
1 stop6h 53m
Deal found 8/22![Delta logo]()
$401
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:35 pm -
2 stops11h 44m
Wed 11/257:00 pm -
1 stop6h 51m
Deal found 8/22![Delta logo]()
$401
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated August 27, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated August 27, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:40 am -
1 stop28h 10m
Wed 9/912:17 pm -
1 stop25h 19m
Deal found 8/24![Frontier logo]()
$326
This CheapOair deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/711:40 am -
1 stop28h 10m
Fri 9/1112:17 pm -
1 stop25h 19m
Deal found 8/23![Frontier logo]()
$338
This CheapOair deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:24 pm -
1 stop20h 53m
Wed 9/168:10 pm -
1 stop17h 33m
Deal found 8/26![Frontier logo]()
$337
This Cheapflightsfares deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:38 pm -
1 stop28h 39m
Sun 9/1312:27 pm -
1 stop25h 27m
Deal found 8/26![Frontier logo]()
$308
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:35 pm -
1 stop6h 50m
Sat 9/268:30 am -
Nonstop4h 10m
Deal found 8/22![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:10 pm -
1 stop5h 34m
Fri 9/256:55 pm -
2 stops15h 48m
Deal found 8/23![Delta logo]()
$345
This Alaska Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:16 am -
Nonstop3h 54m
Sat 9/266:08 pm -
Nonstop4h 12m
Deal found 8/24![Alaska Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/231:05 pm -
1 stop7h 45m
Sat 9/268:30 am -
Nonstop4h 10m
Deal found 8/22![Southwest logo]()
$327
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:49 am -
1 stop25h 35m
Deal found 8/23![Frontier logo]()
$135
This Travelocity deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:21 am -
2 stops12h 38m
Deal found 8/27![Alaska Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:38 pm -
1 stop28h 39m
Deal found 8/22![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:02 pm -
2 stops27h 38m
Deal found 8/26![Frontier logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:39 pm -
2 stops46h 31m
Deal found 8/24![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:38 pm -
1 stop28h 39m
Deal found 8/22![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:49 am -
2 stops27h 51m
Deal found 8/25![Frontier logo]()
$156
This Alaska Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:16 am -
Nonstop3h 54m
Deal found 8/25![Alaska Airlines logo]()
$159
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $273 (Expedia) |
One-way from | $135 (Kiwi.com) |
Popular in | July |
Cheapest in | November |
Average price | $377 |
Good round-trip deal | $346 or less |
Good one-way deal | $288 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Wed 12/2
7:38 pm-9:23 am
2 stops11h 45m
Lambert-St Louis
Wed 12/9
10:18 am-10:06 pm
2 stops13h 48m
$353
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Thu 10/29
5:30 am-5:30 pm
2 stops10h 00m
Lambert-St Louis
Tue 11/3
1:55 pm-9:25 pm
2 stops9h 30m
$363
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Thu 10/8
11:12 pm-9:44 am
1 stop8h 32m
Lambert-St Louis
Tue 10/13
7:00 pm-11:47 pm
1 stop6h 47m
$363
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Wed 11/4
10:15 am-9:05 pm
2 stops8h 50m
Lambert-St Louis
Sun 11/8
7:15 pm-11:55 pm
1 stop6h 40m
$368
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Tue 9/22
11:16 am-5:10 pm
Nonstop3h 54m
Lambert-St Louis
Fri 9/25
6:29 am-1:37 pm
1 stop9h 08m
$382
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Wed 12/2
11:32 am-11:26 pm
2 stops9h 54m
Lambert-St Louis
Sun 12/6
7:08 am-6:58 pm
2 stops13h 50m
$388
Quickest round-trip
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Wed 9/9
5:40 am-1:30 pm
1 stop5h 50m
Lambert-St Louis
Thu 9/17
6:55 pm-11:40 pm
1 stop6h 45m
$398
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Fri 11/13
7:33 pm-10:39 am
2 stops13h 06m
Lambert-St Louis
Mon 11/16
7:00 pm-11:53 pm
1 stop6h 53m
$401
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Mon 11/16
7:35 pm-9:19 am
2 stops11h 44m
Lambert-St Louis
Wed 11/25
7:00 pm-11:51 pm
1 stop6h 51m
$401
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Thu 11/5
8:00 am-7:10 pm
2 stops9h 10m
Lambert-St Louis
Mon 11/9
4:00 pm-11:20 pm
2 stops9h 20m
$408
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PDX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
How far ahead should I book a flight from Portland to St. Louis?
The best time to book flights from Portland to St. Louis is 72 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, November is the cheapest month in which you can book a flight from Portland to St. Louis (average of $304). Flying from Portland to St. Louis in July is currently the most expensive (average of $417). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PDX to STL?
Find hourly flight availability from Portland to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 27, 2026.
When flying from Portland to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 27, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Food
7.0
Crew
8.6
Overall
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Find flights from Portland to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on August 27, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on August 27, 2026.
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Other flights to St. Louis
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Top 6 airlines flying from Portland to St. Louis
Discover the top 6 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$177 | Average$337 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$213 | Average$394 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$248 | Average$403 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$377 | FlexibilityNo cancel fee | On-time71% |