$128+ Cheap flights from Portland to St. Louis (PDX - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
Dec 6 — Dec 131
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in May or January, booked 74 days in advance, depart on a Tuesday or Friday and return on a Tuesday
Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:09 pm -
1 stop15h 57m
Mon 12/77:54 pm -
1 stop22h 16m
Deal found 11/1![Frontier logo]()
$258
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:58 pm -
1 stop18h 59m
Wed 12/97:54 pm -
1 stop19h 09m
Deal found 11/4![Frontier logo]()
$261
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:58 pm -
1 stop18h 59m
Sat 1/27:03 pm -
1 stop18h 26m
Deal found 11/2![Frontier logo]()
$317
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
1 stop25h 21m
Thu 11/191:28 pm -
1 stop25h 35m
Deal found 11/2![Frontier logo]()
$322
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:58 pm -
1 stop24h 22m
Sun 11/225:15 pm -
1 stop21h 21m
Deal found 11/2![Frontier logo]()
$326
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:02 pm -
1 stop21h 01m
Tue 11/245:15 pm -
1 stop18h 17m
Deal found 11/5![Frontier logo]()
$327
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:52 pm -
1 stop19h 11m
Thu 12/32:02 pm -
1 stop23h 51m
Deal found 11/5![Frontier logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:04 pm -
1 stop24h 22m
Wed 12/306:21 pm -
2 stops19h 48m
Deal found 11/2![Frontier logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:09 pm -
1 stop15h 57m
Tue 12/86:20 pm -
2 stops44h 43m
Deal found 11/1![Frontier logo]()
$346
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 6, 2026.
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:45 am -
1 stop6h 51m
Thu 12/32:17 pm -
1 stop9h 50m
Deal found 11/4![Delta logo]()
$359
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:15 pm -
1 stop5h 42m
Wed 12/169:40 am -
2 stops10h 27m
Deal found 11/5![United Airlines logo]()
$364
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:40 am -
2 stops12h 30m
Wed 12/96:25 am -
1 stop12h 20m
Deal found 11/3![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:30 pm -
1 stop5h 58m
Tue 12/86:03 am -
1 stop6h 45m
Deal found 11/3![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:20 am -
1 stop6h 18m
Tue 1/127:05 am -
1 stop7h 23m
Deal found 11/2![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1712:35 pm -
2 stops10h 25m
Tue 3/2311:50 am -
1 stop8h 55m
Deal found 11/3![Southwest logo]()
$414
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/11:05 pm -
2 stops8h 05m
Tue 12/812:40 pm -
2 stops11h 10m
Deal found 11/1![Southwest logo]()
$419
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:17 pm -
1 stop8h 02m
Sun 12/136:03 am -
1 stop8h 45m
Deal found 11/3![Delta logo]()
$384
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:05 am -
1 stop6h 39m
Wed 12/307:46 pm -
1 stop6h 13m
Deal found 11/1![Delta logo]()
$389
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/99:23 am -
2 stops10h 05m
Sat 12/1211:44 am -
2 stops11h 14m
Deal found 11/1![Delta logo]()
$423
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated November 6, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated November 6, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:02 pm -
1 stop25h 21m
Thu 11/191:28 pm -
1 stop25h 35m
Deal found 11/2![Frontier logo]()
$322
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:02 pm -
1 stop21h 01m
Tue 11/245:15 pm -
1 stop18h 17m
Deal found 11/5![Frontier logo]()
$327
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:58 pm -
1 stop24h 22m
Sun 11/225:15 pm -
1 stop21h 21m
Deal found 11/2![Frontier logo]()
$326
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/261:52 pm -
1 stop19h 11m
Thu 12/32:02 pm -
1 stop23h 51m
Deal found 11/5![Frontier logo]()
$328
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:09 pm -
1 stop15h 57m
Mon 12/77:54 pm -
1 stop22h 16m
Deal found 11/1![Frontier logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:09 pm -
1 stop15h 57m
Tue 12/86:20 pm -
2 stops44h 43m
Deal found 11/1![Frontier logo]()
$346
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:58 pm -
1 stop18h 59m
Wed 12/97:54 pm -
1 stop19h 09m
Deal found 11/4![Frontier logo]()
$261
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:58 pm -
1 stop18h 59m
Sat 1/27:03 pm -
1 stop18h 26m
Deal found 11/2![Frontier logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:04 pm -
1 stop24h 22m
Wed 12/306:21 pm -
2 stops19h 48m
Deal found 11/2![Frontier logo]()
$342
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated November 6, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/711:12 am -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$128
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:58 pm -
1 stop18h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$134
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/241:04 pm -
1 stop24h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:51 pm -
2 stops37h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$150
This Cheapflightsfares deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:53 pm -
1 stop19h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/710:22 am -
2 stops21h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:04 pm -
1 stop24h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$168
This Cheapflightsfares deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/284:29 pm -
1 stop15h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Frontier logo]()
$169
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2712:59 pm -
1 stop7h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$175
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/251:25 pm -
1 stop5h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$180
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (Cheapflightsfares) |
One-way from | $128 (Cheapflightsfares) |
Popular in | October |
Cheapest in | May |
Average price | $432 |
Good one-way deal | $378 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sat 2/27
12:59 pm-10:25 pm
1 stop7h 26m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$175
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Fri 11/27
12:00 pm-8:29 pm
1 stop6h 29m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$180
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Fri 12/4
11:17 pm-9:19 am
1 stop8h 02m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$180
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Fri 12/25
1:25 pm-9:06 pm
1 stop5h 41m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$180
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sat 12/19
5:18 pm-12:46 am
1 stop5h 28m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$180
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Fri 12/25
11:40 am-10:00 pm
2 stops8h 20m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$185
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sun 12/20
5:18 pm-12:46 am
1 stop5h 28m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$205
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sun 1/3
5:18 pm-12:46 am
1 stop5h 28m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$205
Quickest round-trip
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sun 4/4
6:00 am-1:23 pm
1 stop5h 23m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$210
PortlandSt. Louis
PDX Portland - STL Lambert-St Louis
PDXSTL
Portland
Sat 4/3
1:45 pm-9:36 pm
1 stop5h 51m
Lambert-St Louis
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$210
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PDX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
How far ahead should I book a flight from Portland to St. Louis?
The best time to book flights from Portland to St. Louis is 72 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, May is the cheapest month in which you can book a flight from Portland to St. Louis (average of $309). Flying from Portland to St. Louis in October is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to St. Louis?
Airfare is below average for this route at the moment.
Portland to St. Louis flights typically cost between $362 and $547 in December.The cheapest round-trip price found within the last 5 days was $258 on Frontier (Dec 1-Dec 7).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated November 6, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Crew
8.6
Entertainment
7.5
Boarding
8.1
Overall
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Edwardsville
Glencoe
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Portland and St. Louis flights
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Top 6 airlines flying from Portland to St. Louis
Discover the top 6 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$287 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$177 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$208 | Average$376 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$213 | Average$400 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$248 | Average$418 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$308 | Average$551 | FlexibilityNo cancel fee | On-time63% |