$78+ Cheap flights from Portland to St. Louis (PDX - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — STL
May 7 — May 141
Round-trip
1 adult, Economy
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Find cheap flights from Portland to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Portland to Lambert-St Louis are usually found in November or September, booked 81 days in advance, depart on a Tuesday or Monday and return on a Tuesday
Cheap flight deals from Portland to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This CheapOair deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:48 am
PDX
- STL
1 stop5h 33m
Frontier
Mon 4/278:17 pm
STL
- PDX
1 stop17h 35m
Frontier
Deal found 4/2![Frontier logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Thu 5/1412:36 pm
STL
- PDX
2 stops30h 10m
Frontier
Deal found 4/4![Frontier logo]()
$238
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Wed 5/136:51 pm
STL
- PDX
1 stop28h 00m
Frontier
Deal found 4/4![Frontier logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Tue 5/126:51 pm
STL
- PDX
2 stops42h 59m
Frontier
Deal found 4/4![Frontier logo]()
$249
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:48 am
PDX
- STL
1 stop5h 44m
Frontier
Thu 5/1412:36 pm
STL
- PDX
1 stop10h 15m
Frontier
Deal found 4/5![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:38 pm
PDX
- STL
2 stops19h 52m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 4/6![Frontier logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:38 pm
PDX
- STL
2 stops32h 41m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 4/6![Frontier logo]()
$256
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 am
PDX
- STL
1 stop9h 28m
American Airlines
Sat 5/307:20 pm
STL
- PDX
1 stop7h 30m
American Airlines
Deal found 4/3![American Airlines logo]()
$257
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Tue 6/98:08 pm
STL
- PDX
1 stop22h 49m
Frontier
Deal found 4/6![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:35 am
PDX
- STL
2 stops8h 45m
Southwest
Tue 5/56:30 pm
STL
- PDX
1 stop6h 40m
Southwest
Deal found 4/3![Southwest logo]()
$262
Best flights from Portland to St. LouisDiscover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/611:55 pm
PDX
- STL
1 stop8h 20m
Southwest
Sat 5/92:05 pm
STL
- PDX
2 stops10h 00m
Southwest
Deal found 4/3![Southwest logo]()
$262
This Alaska Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:52 pm
PDX
- STL
1 stop8h 07m
Alaska Airlines
Wed 5/135:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/4![Alaska Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:41 pm
PDX
- STL
1 stop6h 38m
United Airlines
Sat 5/96:00 am
STL
- PDX
1 stop8h 43m
United Airlines
Deal found 4/2![United Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:05 pm
PDX
- STL
1 stop5h 20m
Delta
Fri 5/157:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 4/4![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/410:55 pm
PDX
- STL
1 stop7h 44m
United Airlines
Fri 5/85:59 pm
STL
- PDX
1 stop6h 55m
United Airlines
Deal found 4/2![United Airlines logo]()
$292
This Alaska Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:52 pm
PDX
- STL
1 stop8h 07m
Alaska Airlines
Thu 5/145:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/6![Alaska Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:40 am
PDX
- STL
1 stop6h 00m
Delta
Sat 8/226:59 pm
STL
- PDX
1 stop6h 42m
Delta
Deal found 4/2![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1912:31 am
PDX
- STL
1 stop7h 57m
Delta
Wed 6/243:57 pm
STL
- PDX
1 stop9h 24m
Delta
Deal found 4/4![Delta logo]()
$334
This Alaska Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:37 am
PDX
- STL
Nonstop4h 00m
Alaska Airlines
Tue 6/95:33 pm
STL
- PDX
Nonstop4h 17m
Alaska Airlines
Deal found 4/4![Alaska Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:11 pm
PDX
- STL
2 stops10h 35m
Delta
Wed 5/137:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 4/4![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:20 am
PDX
- STL
2 stops11h 10m
Delta
Wed 5/277:59 pm
STL
- PDX
1 stop5h 45m
Delta
Deal found 4/2![Delta logo]()
$371
Last-minute flights from Portland to St. LouisDiscover last-minute flight deals from Portland to St. Louis. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to St. Louis. Data last updated April 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:38 pm
PDX
- STL
2 stops32h 41m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 4/6![Frontier logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2212:38 pm
PDX
- STL
2 stops19h 52m
Frontier
Sat 5/28:17 pm
STL
- PDX
1 stop16h 03m
Frontier
Deal found 4/6![Frontier logo]()
$251
This CheapOair deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:48 am
PDX
- STL
1 stop5h 33m
Frontier
Mon 4/278:17 pm
STL
- PDX
1 stop17h 35m
Frontier
Deal found 4/2![Frontier logo]()
$216
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:48 am
PDX
- STL
1 stop5h 44m
Frontier
Thu 5/1412:36 pm
STL
- PDX
1 stop10h 15m
Frontier
Deal found 4/5![Frontier logo]()
$250
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:35 am
PDX
- STL
2 stops8h 45m
Southwest
Tue 5/56:30 pm
STL
- PDX
1 stop6h 40m
Southwest
Deal found 4/3![Southwest logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Thu 5/1412:36 pm
STL
- PDX
2 stops30h 10m
Frontier
Deal found 4/4![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Tue 5/126:51 pm
STL
- PDX
2 stops42h 59m
Frontier
Deal found 4/4![Frontier logo]()
$249
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Wed 5/136:51 pm
STL
- PDX
1 stop28h 00m
Frontier
Deal found 4/4![Frontier logo]()
$241
This CheapOair deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Thu 5/1412:36 pm
STL
- PDX
1 stop10h 15m
Frontier
Deal found 4/2![Frontier logo]()
$261
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 am
PDX
- STL
1 stop9h 28m
American Airlines
Sat 5/307:20 pm
STL
- PDX
1 stop7h 30m
American Airlines
Deal found 4/3![American Airlines logo]()
$257
One-way flights from Portland to St. LouisSearch for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:38 pm
PDX
- STL
1 stop28h 43m
Frontier
Deal found 4/3![Frontier logo]()
$78
This Priceline deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2611:15 am
PDX
- STL
1 stop6h 06m
Frontier
Deal found 4/5![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 4/3![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:48 am
PDX
- STL
1 stop29h 44m
Frontier
Deal found 4/3![Frontier logo]()
$90
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:46 pm
PDX
- STL
1 stop19h 20m
Frontier
Deal found 4/5![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:46 pm
PDX
- STL
1 stop23h 37m
Frontier
Deal found 4/6![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 4/6![Frontier logo]()
$101
This Priceline deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:15 am
PDX
- STL
1 stop6h 56m
Frontier
Deal found 4/5![Frontier logo]()
$105
This Expedia deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:35 pm
PDX
- STL
1 stop28h 48m
Frontier
Deal found 4/3![Frontier logo]()
$111
Find flight deals from Portland to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $216 (CheapOair) |
One-way from | $78 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $399 |
Good round-trip deal | $297 or less |
Good one-way deal | $164 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Wed 5/6
11:55 pm-10:15 am
1 stop8h 20m
Lambert-St Louis
Sat 5/9
2:05 pm-10:05 pm
2 stops10h 00m
$262
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 5/5
1:52 pm-11:59 pm
1 stop8h 07m
Lambert-St Louis
Wed 5/13
5:33 pm-7:50 pm
Nonstop4h 17m
$267
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Sat 5/2
2:41 pm-11:19 pm
1 stop6h 38m
Lambert-St Louis
Sat 5/9
6:00 am-12:43 pm
1 stop8h 43m
$277
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Mon 5/4
10:55 pm-8:39 am
1 stop7h 44m
Lambert-St Louis
Fri 5/8
5:59 pm-10:54 pm
1 stop6h 55m
$292
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 5/5
5:05 pm-12:25 am
1 stop5h 20m
Lambert-St Louis
Fri 5/15
7:59 pm-11:44 pm
1 stop5h 45m
$293
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Tue 5/5
1:52 pm-11:59 pm
1 stop8h 07m
Lambert-St Louis
Thu 5/14
5:33 pm-7:50 pm
Nonstop4h 17m
$332
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Wed 8/12
12:40 am-8:40 am
1 stop6h 00m
Lambert-St Louis
Sat 8/22
6:59 pm-11:41 pm
1 stop6h 42m
$334
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Fri 6/19
12:31 am-10:28 am
1 stop7h 57m
Lambert-St Louis
Wed 6/24
3:57 pm-11:21 pm
1 stop9h 24m
$334
Quickest round-trip
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Thu 6/4
10:37 am-4:37 pm
Nonstop4h 00m
Lambert-St Louis
Tue 6/9
5:33 pm-7:50 pm
Nonstop4h 17m
$358
PortlandSt. Louis
PDX - STL
PDXSTL
Portland
Mon 5/11
8:11 pm-8:46 am
2 stops10h 35m
Lambert-St Louis
Wed 5/13
7:59 pm-11:44 pm
1 stop5h 45m
$371
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Portland to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Portland-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
PDX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to St. Louis
How far ahead should I book a flight from Portland to St. Louis?
Use this chart to determine the optimal time to book a round-trip flight from Portland to St. Louis. Price data was last updated on April 3, 2026.
The best time to book flights from Portland to St. Louis is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Portland to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Portland to St. Louis (average of $165). Flying from Portland to St. Louis in February is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 7, 2026.
See what other customers who have flown with Southwest,Alaska Airlines, andDelta from Portland to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Portland and St. Louis flights
Browse other Portland and St. Louis flight options. Last updated on April 7, 2026.
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Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on April 7, 2026.
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Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 7, 2026.
Top 6 airlines flying from Portland to St. Louis
Discover the top 6 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$75 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$188 | Average$372 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$326 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$226 | Average$377 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$371 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$408 | FlexibilityNo cancel fee | On-time63% |