$123+ Cheap flights from Pittsburgh to St. Louis (PIT - STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — STL
Nov 29 — Dec 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Pittsburgh to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Pittsburgh to Lambert-St Louis are usually found in October or August, booked 85 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday
Cheap flight deals from Pittsburgh to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Pittsburgh to St. LouisExplore the most affordable flight options available from Pittsburgh to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Pittsburgh to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop25h 42m
Mon 11/236:05 pm -
1 stop22h 59m
Deal found 10/28![Frontier logo]()
$202
This Trip.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:59 pm -
1 stop6h 00m
Wed 12/26:13 pm -
1 stop22h 15m
Deal found 10/28![Frontier logo]()
$206
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:30 pm -
Nonstop1h 55m
Thu 11/196:15 pm -
Nonstop1h 40m
Deal found 10/26![Southwest logo]()
$211
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:10 pm -
1 stop4h 05m
Wed 12/26:15 pm -
Nonstop1h 40m
Deal found 10/28![Southwest logo]()
$221
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:57 pm -
1 stop5h 01m
Fri 12/43:40 pm -
1 stop4h 37m
Deal found 10/28![American Airlines logo]()
$240
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:20 pm -
1 stop3h 50m
Fri 12/46:15 pm -
Nonstop1h 40m
Deal found 10/28![Southwest logo]()
$241
This CheapOair deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:28 pm -
1 stop6h 44m
Sun 12/136:20 pm -
1 stop22h 13m
Deal found 10/25![Frontier logo]()
$242
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:50 am -
Nonstop1h 55m
Sun 12/67:55 pm -
Nonstop1h 40m
Deal found 10/27![Southwest logo]()
$254
Best flights from Pittsburgh to St. LouisDiscover carefully curated flight deals from Pittsburgh to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Pittsburgh to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:30 pm -
Nonstop1h 55m
Thu 12/1010:15 am -
Nonstop1h 30m
Deal found 10/28![Southwest logo]()
$211
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:00 am -
1 stop5h 04m
Mon 2/84:56 pm -
1 stop6h 50m
Deal found 10/26![Delta logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/298:40 am -
1 stop4h 33m
Sun 1/319:05 am -
1 stop4h 42m
Deal found 10/26![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:50 am -
Nonstop1h 55m
Mon 11/237:55 pm -
Nonstop1h 40m
Deal found 10/28![Southwest logo]()
$211
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/265:40 am -
1 stop6h 24m
Fri 1/296:59 pm -
1 stop4h 46m
Deal found 10/26![Delta logo]()
$267
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:30 pm -
Nonstop1h 55m
Sun 12/64:30 pm -
1 stop5h 55m
Deal found 10/27![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:07 pm -
1 stop3h 52m
Sun 11/296:50 pm -
1 stop6h 41m
Deal found 10/26![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/66:50 am -
Nonstop1h 55m
Sat 2/133:55 pm -
1 stop7h 10m
Deal found 10/28![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:45 am -
2 stops6h 10m
Thu 12/310:55 am -
2 stops6h 00m
Deal found 10/27![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:50 am -
Nonstop2h 00m
Sun 12/205:30 am -
1 stop3h 30m
Deal found 10/29![Southwest logo]()
$321
Last-minute flights from Pittsburgh to St. LouisDiscover last-minute flight deals from Pittsburgh to St. Louis. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to St. Louis. Data last updated October 30, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:30 pm -
Nonstop1h 55m
Thu 11/196:15 pm -
Nonstop1h 40m
Deal found 10/26![Southwest logo]()
$211
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:43 am -
1 stop25h 42m
Mon 11/236:05 pm -
1 stop22h 59m
Deal found 10/28![Frontier logo]()
$202
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:29 pm -
1 stop4h 32m
Sat 11/287:26 am -
1 stop4h 04m
Deal found 10/28![American Airlines logo]()
$287
This Trip.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:59 pm -
1 stop6h 00m
Wed 12/26:13 pm -
1 stop22h 15m
Deal found 10/28![Frontier logo]()
$206
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:10 pm -
1 stop4h 05m
Wed 12/26:15 pm -
Nonstop1h 40m
Deal found 10/28![Southwest logo]()
$221
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:07 pm -
1 stop3h 52m
Sun 11/296:50 pm -
1 stop6h 41m
Deal found 10/26![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:45 am -
2 stops6h 10m
Thu 12/310:55 am -
2 stops6h 00m
Deal found 10/27![Southwest logo]()
$298
One-way flights from Pittsburgh to St. LouisSearch for one-way flight options from Pittsburgh to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Pittsburgh to St. Louis. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:17 pm -
1 stop7h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Frontier logo]()
$123
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:30 am -
Nonstop2h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$126
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:50 am -
Nonstop1h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$129
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:10 am -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:55 am -
3 stops31h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:27 pm -
2 stops25h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Frontier logo]()
$168
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:15 am -
2 stops8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Southwest logo]()
$178
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/205:20 pm -
3 stops18h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:15 pm -
2 stops24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$199
Find flight deals from Pittsburgh to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Pittsburgh (PIT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (CheapOair) |
One-way from | $123 (Priceline) |
Popular in | June |
Cheapest in | October |
Average price | $274 |
Good round-trip deal | $308 or less |
Good one-way deal | $218 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Pittsburgh to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Fri 11/27
6:30 am-7:30 am
Nonstop2h 00m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$126
Quickest round-trip
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sun 12/20
8:15 pm-9:00 pm
Nonstop1h 45m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$163
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 11/28
6:00 am-7:05 am
Nonstop2h 05m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$207
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Mon 12/7
6:30 pm-7:25 pm
Nonstop1h 55m
Lambert-St Louis
Thu 12/10
10:15 am-12:45 pm
Nonstop1h 30m
$211
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 11/19
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Mon 11/23
7:55 pm-10:35 pm
Nonstop1h 40m
$211
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 11/12
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$264
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Thu 12/3
6:30 pm-7:25 pm
Nonstop1h 55m
Lambert-St Louis
Sun 12/6
4:30 pm-11:25 pm
1 stop5h 55m
$264
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Fri 2/5
7:00 am-11:04 am
1 stop5h 04m
Lambert-St Louis
Mon 2/8
4:56 pm-12:46 am
1 stop6h 50m
$267
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Tue 1/26
5:40 am-11:04 am
1 stop6h 24m
Lambert-St Louis
Fri 1/29
6:59 pm-12:45 am
1 stop4h 46m
$267
PittsburghSt. Louis
PIT Pittsburgh - STL Lambert-St Louis
PITSTL
Pittsburgh
Sat 2/6
6:50 am-7:45 am
Nonstop1h 55m
Lambert-St Louis
Sat 2/13
3:55 pm-12:05 am
1 stop7h 10m
$267
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Pittsburgh to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Pittsburgh to St. Louis in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Pittsburgh-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Pittsburgh-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Pittsburgh-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Pittsburgh-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Pittsburgh-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Pittsburgh to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Pittsburgh with our price prediction graph.
PIT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to St. Louis
How far ahead should I book a flight from Pittsburgh to St. Louis?
Booking 84 days in advance of your planned departure date is, on average, the best time to get cheap flights from Pittsburgh to St. Louis. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Pittsburgh to St. Louis?
Currently, October is the cheapest month in which you can book a flight from Pittsburgh to St. Louis (average of $274). Flying from Pittsburgh to St. Louis in June is currently the most expensive (average of $470). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PIT to STL?
Find hourly flight availability from Pittsburgh to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
A simple way to save on the total cost of your ticket is to fly from Pittsburgh to St. Louis at noon. If you’re flexible enough to do this you can expect to save up to 18% on your trip compared to booking a flight in the morning.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 30, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Pittsburgh to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Overall
7.9
Crew
8.6
Entertainment
7.4
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Wentzville
Maryland Heights
Chesterfield
Collinsville
Edwardsville
Glencoe
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Pittsburgh
Popular flights
St. Louis flight routes
Alternative routes for Pittsburgh to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to St. Louis by cabin class
Find flights from Pittsburgh to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and St. Louis flights
Browse other Pittsburgh and St. Louis flight options. Last updated on October 30, 2026.
Other flights from Pittsburgh
Browse through other flights departing from Pittsburgh. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Top 4 airlines flying from Pittsburgh to St. Louis
Discover the top 4 airlines that operate flights from Pittsburgh to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$174 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$188 | Average$388 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$217 | Average$343 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$279 | Average$440 | FlexibilityNo cancel fee | On-time69% |