In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

What is the cheapest time of day to fly from OD3 to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Odessa to St. Louis as you normally would.

What airport do you fly into for flights to St. Louis from Odessa?

Most people fly into Lambert-St Louis (STL) if they book a flight to St. Louis from Odessa. On average, Lambert-St Louis has 0 inbound flights from Odessa per day from 1 airline. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.

Can I find deals for flights from Odessa to St. Louis that include hotel bookings?

Yes. In addition to deals on Odessa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Odessa to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to St. Louis.

Can I find deals for business class flights from Odessa to St. Louis?

Yes. Cheapflights offers flight deals from Odessa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Flights from Odessa to St. Louis

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Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest from Odessa to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,257 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

8.0

Very good

4,257 reviews

Southwest

8.0

Very good

4,257 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What airport do you fly into for flights to St. Louis from Odessa?
Most people fly into Lambert-St Louis (STL) if they book a flight to St. Louis from Odessa. On average, Lambert-St Louis has 0 inbound flights from Odessa per day from 1 airline. Lambert-St Louis is conveniently located just 12.7 mi from St. Louis’s city center.
Can I find deals for flights from Odessa to St. Louis that include hotel bookings?
Yes. In addition to deals on Odessa to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Odessa to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to St. Louis.
Can I find deals for business class flights from Odessa to St. Louis?
Yes. Cheapflights offers flight deals from Odessa to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top airline flying from Odessa to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$196	Average$408	FlexibilityNo cancel fee	On-time63%

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Find cheap flights from Odessa to St. Louis with Cheapflights

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3. Compare prices and book

Find flight deals from Odessa to St. Louis

Keep the following information in mind while searching for Odessa to St. Louis flight deals. Data was last updated January 3, 2026.

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Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest from Odessa to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Odessa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Odessa?

Can I find deals for flights from Odessa to St. Louis that include hotel bookings?

How can I find direct flights from Odessa to St. Louis?

Can I find deals for business class flights from Odessa to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Odessa to St. Louis

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Complete your trip

Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Odessa to St. Louis by cabin class

Find flights from Odessa to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Odessa and St. Louis flights

Browse other Odessa and St. Louis flight options. Last updated on January 3, 2026.

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Other flights to St. Louis

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Cheap flights from Odessa, TX to St. Louis (STL)

Find cheap flights from Odessa to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Odessa to St. Louis

Keep the following information in mind while searching for Odessa to St. Louis flight deals. Data was last updated January 3, 2026.

Most accurate provider

Most trusted provider

Reviews of airlines servicing St. Louis

See what other customers who have flown with Southwest from Odessa to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Odessa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to St. Louis from Odessa?

Can I find deals for flights from Odessa to St. Louis that include hotel bookings?

How can I find direct flights from Odessa to St. Louis?

Can I find deals for business class flights from Odessa to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Odessa to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Odessa to St. Louis

100% Free

Book with Flexibility

Travel Smart