St. Louis

$79+ Cheap flights from Myrtle Beach to St. Louis (MYR - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/10. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — STL
Jun 17 — Jun 241
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Cheap flight deals from Myrtle Beach to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$187
(American Airlines)

One-way from

$79
(American Airlines)

Popular in

February

Cheapest in

August

Average price

$323

Good round-trip deal

$407 or less
From Myrtle Beach Intl to Lambert-St Louis
One-way flight from Myrtle Beach Intl to Lambert-St Louis
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Average for round-trip flights in June 2025
Price to beat on a round-trip flight from Myrtle Beach Intl to Lambert-St Louis.

Find flight deals from Myrtle Beach to St. Louis

Cheapest flights from Myrtle Beach to St. Louis
Explore the most affordable flight options available from Myrtle Beach to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/145:23 amMYR - STL
1 stop3h 41mAmerican Airlines
Sun 8/175:27 amSTL - MYR
1 stop3h 28mAmerican Airlines
Deal found 6/11$187
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/98:58 pmMYR - STL
1 stop13h 54mSpirit Airlines
Wed 7/1611:24 amSTL - MYR
1 stop9h 53mSpirit Airlines
Deal found 6/11$201
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:10 pmMYR - STL
1 stop5h 15mSouthwest
Sun 8/171:00 pmSTL - MYR
Nonstop1h 55mSouthwest
Deal found 6/11$207
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/311:00 amMYR - STL
1 stop4h 36mDelta
Sat 7/56:30 amSTL - MYR
1 stop6h 27mDelta
Deal found 6/12$307
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/811:28 amMYR - STL
3 stops30h 17mMultiple Airlines
Sat 7/1210:45 amSTL - MYR
1 stop10h 32mMultiple Airlines
Deal found 6/10$336
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/264:50 pmMYR - STL
1 stop6h 55mUnited Airlines
Mon 6/308:00 amSTL - MYR
1 stop5h 35mUnited Airlines
Deal found 6/11$507

Cheapflights Fare Finder

Customize your flight search to find flights from Myrtle Beach to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Myrtle Beach to St. Louis that are best for you.

Fly from

Myrtle Beach

Fly to

St. Louis

Route

Depart

Return

Price

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/14

5:23 am-8:04 am

1 stop3h 41m

Lambert-St Louis

Sun 8/17

5:27 am-9:55 am

1 stop3h 28m

$187

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Wed 7/9

8:58 pm-9:52 am

1 stop13h 54m

Lambert-St Louis

Wed 7/16

11:24 am-10:17 pm

1 stop9h 53m

$201

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 8/14

7:10 pm-11:25 pm

1 stop5h 15m

Lambert-St Louis

Sun 8/17

1:00 pm-3:55 pm

Nonstop1h 55m

$207

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 7/3

11:00 am-2:36 pm

1 stop4h 36m

Lambert-St Louis

Sat 7/5

6:30 am-1:57 pm

1 stop6h 27m

$307

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Tue 7/8

11:28 am-4:45 pm

3 stops30h 17m

Lambert-St Louis

Sat 7/12

10:45 am-10:17 pm

1 stop10h 32m

$336

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 6/26

4:50 pm-10:45 pm

1 stop6h 55m

Lambert-St Louis

Mon 6/30

8:00 am-2:35 pm

1 stop5h 35m

$507

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 7/10

7:50 pm-11:59 pm

1 stop5h 09m

$79

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Wed 7/16

8:58 pm-9:52 am

1 stop13h 54m

$87

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Thu 7/17

7:55 pm-11:20 pm

1 stop4h 25m

$89

Myrtle BeachSt. Louis

MYR - STL

MYRSTL

Myrtle Beach Intl

Mon 7/28

9:47 pm-4:31 pm

2 stops19h 44m

$146

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 12 results
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Best time to book a flight from Myrtle Beach to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to St. Louis

What is the cheapest month to book a flight from Myrtle Beach to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $311). Flying from Myrtle Beach to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to STL?

Find hourly flight availability from Myrtle Beach to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

One of the essential ways to save on airfare from Myrtle Beach to St. Louis is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 34% on airfare.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 12, 2025.
See what other customers who have flown with Southwest, Delta and United Airlines from Myrtle Beach to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
8.0
Very good

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Myrtle Beach to St. Louis flight route?

  • What are the cheapest airlines flying from Myrtle Beach to St. Louis round-trip?

    Cheapflights users have booked flights from Myrtle Beach to St. Louis round-trip from $187. Other airlines that can offer you cheap pricing are Spirit Airlines, from $201, and Southwest, from $207. You may be able to fly from Myrtle Beach to St. Louis for 49% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Myrtle Beach to St. Louis one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $79. Users have also found prices from $87 and $89 on Spirit Airlines and Southwest, respectively.

  • What are the cheapest flights from Myrtle Beach to St. Louis?

    On average you can expect to pay $692 for a flight from Myrtle Beach to St. Louis. The cheapest flight overall is $316 while the most popular route, (Myrtle Beach Intl - Lambert-St Louis) is currently priced at $197.

  • Can I find deals for flights from Myrtle Beach to St. Louis that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to St. Louis.

  • Can I find deals for business class flights from Myrtle Beach to St. Louis?

    Yes. Cheapflights offers flight deals from Myrtle Beach to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to St. Louis (average of $311). Flying from Myrtle Beach to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Myrtle Beach?

Book flights to Myrtle Beach if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Festus
Alton
Farmington

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Top 3 airlines flying from Myrtle Beach to St. Louis

Discover the top 3 airlines that operate flights from Myrtle Beach to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$256Average$381FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$292Average$382FlexibilityNo cancel feeOn-time63%

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