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$222+ Cheap flights from Mexico City Federal District to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — STL
Jan 20 — Jan 271
Tue 1/20
Tue 1/27
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to St. Louis

Cheapest flights from Mexico City Federal District to St. Louis
Explore the most affordable flight options available from Mexico City Federal District to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 21, 2025.

This Frontier deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2211:10 amMEX - STL
1 stop11h 23mFrontier
Mon 12/296:00 amSTL - MEX
1 stop11h 15mFrontier
Deal found 12/20$683
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:25 pmMEX - STL
1 stop9h 30mUnited Airlines
Mon 12/296:35 pmSTL - MEX
2 stops15h 30mUnited Airlines
Deal found 12/20$689

Find flight deals from Mexico City Federal District to St. Louis

Keep the following information in mind while searching for Mexico City Federal District to St. Louis flight deals. Data was last updated December 21, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$350
(Frontier)

One-way from

$222
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$614
Provider with most accurate pricing for Mexico City Benito Juarez-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Lambert-St Louis flights.
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From Mexico City Federal District to Lambert-St Louis
Search Deals
One-way flight from Mexico City Federal District to Lambert-St Louis
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to St. Louis that are best for you.

Fly from

Mexico City Federal District

Fly to

St. Louis

Route

Depart

Return

Price

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Wed 1/21

12:40 am-11:33 pm

2 stops22h 53m

Lambert-St Louis

Mon 1/26

10:16 am-7:45 pm

1 stop9h 29m

$350

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Mon 2/2

6:20 am-6:51 am

2 stops48h 31m

Lambert-St Louis

Mon 2/9

5:42 pm-7:45 pm

1 stop26h 03m

$375

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Sat 1/17

11:10 am-10:34 pm

1 stop11h 24m

Lambert-St Louis

Sat 1/24

3:46 pm-10:00 pm

2 stops30h 14m

$379

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Thu 1/22

11:10 am-11:33 pm

1 stop12h 23m

Lambert-St Louis

Mon 1/26

5:42 pm-7:45 pm

1 stop26h 03m

$381

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Fri 4/3

11:05 am-10:33 pm

1 stop10h 28m

Lambert-St Louis

Tue 4/7

10:42 am-10:45 pm

2 stops13h 03m

$466

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Mon 3/30

11:05 am-11:19 pm

1 stop11h 14m

Lambert-St Louis

Tue 4/7

10:42 am-9:50 pm

2 stops12h 08m

$466

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Sat 4/4

11:05 am-10:33 pm

1 stop10h 28m

Lambert-St Louis

Tue 4/7

6:00 am-4:40 pm

1 stop11h 40m

$475

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Wed 4/1

11:05 am-10:33 pm

1 stop10h 28m

Lambert-St Louis

Mon 4/6

6:00 am-4:40 pm

1 stop11h 40m

$475

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Sat 1/31

11:10 am-11:33 pm

1 stop12h 23m

$222

Mexico CitySt. Louis

MEX - STL

MEXSTL

Mexico City Benito Juarez

Mon 1/12

8:10 am-10:34 pm

2 stops38h 24m

$222

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/19

Showing 1-10 of 15 results
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Best time to book a flight from Mexico City Federal District to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to St. Louis

What is the cheapest month to book a flight from Mexico City Federal District to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Mexico City Federal District to St. Louis (average of $435). Flying from Mexico City Federal District to St. Louis in November is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DF to STL?

Find hourly flight availability from Mexico City Federal District to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 21, 2025.

A simple way to save on the total cost of your ticket is to fly from Mexico City Federal District to St. Louis at noon. If you’re flexible enough to do this you can expect to save up to 72% on your trip compared to booking a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from Mexico City Federal District?

    Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to St. Louis.

  • How long is the flight from Mexico City Federal District to St. Louis?

    Departing from Mexico City Federal District to St. Louis will take you 22h 53m. Mexico City Federal District and St. Louis are separated by a distance of 1431 mi.

  • What are the cheapest airlines to fly from Mexico City Federal District to St. Louis one-way?

    For one-way options, check prices for Volaris. According to our data, you can fly for as low as $215. Users have also found prices from $312 and $317 on Delta and American Airlines, respectively.

  • Can I find deals for flights from Mexico City Federal District to St. Louis that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to St. Louis.

  • Can I find deals for business class flights from Mexico City Federal District to St. Louis?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Mexico City Federal District to St. Louis (average of $435). Flying from Mexico City Federal District to St. Louis in November is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Swansea
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Mexico City Federal District to St. Louis

Discover the top airline that operate flights from Mexico City Federal District to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$466Average$577FlexibilityNo cancel feeOn-time69%

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