$213+ Cheap flights from Mexico City Federal District to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — STL
Mar 16 — Mar 231
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mexico City Federal District to St. Louis
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Best
Last-minute
One-way
Cheapest flights from Mexico City Federal District to St. LouisExplore the most affordable flight options available from Mexico City Federal District to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.
Explore the most affordable flight options available from Mexico City Federal District to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Frontier
Mon 5/183:02 pm
STL
- MEX
2 stops20h 43m
Frontier
Deal found 2/11![Frontier logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:10 pm
MEX
- STL
1 stop16h 05m
Multiple Airlines
Fri 5/88:12 pm
STL
- MEX
2 stops26h 48m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$395
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:40 am
MEX
- STL
1 stop9h 32m
Frontier
Tue 4/286:00 am
STL
- MEX
1 stop11h 40m
Frontier
Deal found 2/11![Frontier logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Tue 4/284:55 pm
STL
- MEX
1 stop27h 50m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$401
This Frontier deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:05 am
MEX
- STL
2 stops18h 45m
Frontier
Mon 4/203:02 pm
STL
- MEX
2 stops20h 43m
Frontier
Deal found 2/13![Frontier logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:45 pm
MEX
- STL
2 stops19h 27m
Multiple Airlines
Tue 4/284:55 pm
STL
- MEX
1 stop27h 50m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:05 pm
MEX
- STL
1 stop15h 09m
Multiple Airlines
Mon 4/136:15 am
STL
- MEX
1 stop21h 20m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$418
Best flights from Mexico City Federal District to St. LouisDiscover carefully curated flight deals from Mexico City Federal District to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 14, 2026.
Discover carefully curated flight deals from Mexico City Federal District to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 14, 2026.
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:40 am
MEX
- STL
1 stop9h 32m
Frontier
Mon 5/183:02 pm
STL
- MEX
2 stops20h 43m
Frontier
Deal found 2/11![Frontier logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:10 pm
MEX
- STL
1 stop16h 05m
Multiple Airlines
Fri 5/88:12 pm
STL
- MEX
2 stops26h 48m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$395
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:40 am
MEX
- STL
1 stop9h 32m
Frontier
Tue 4/286:00 am
STL
- MEX
1 stop11h 40m
Frontier
Deal found 2/11![Frontier logo]()
$400
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Tue 4/284:55 pm
STL
- MEX
1 stop27h 50m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$401
This Frontier deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:40 am
MEX
- STL
1 stop9h 32m
Frontier
Mon 4/203:02 pm
STL
- MEX
2 stops20h 43m
Frontier
Deal found 2/13![Frontier logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:45 pm
MEX
- STL
2 stops19h 27m
Multiple Airlines
Tue 4/284:55 pm
STL
- MEX
1 stop27h 50m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:05 pm
MEX
- STL
1 stop15h 09m
Multiple Airlines
Mon 4/136:15 am
STL
- MEX
1 stop21h 20m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$418
Last-minute flights from Mexico City Federal District to St. LouisDiscover last-minute flight deals from Mexico City Federal District to St. Louis. Data last updated February 14, 2026 and is based on user searches.
Discover last-minute flight deals from Mexico City Federal District to St. Louis. Data last updated February 14, 2026 and is based on user searches.
This eDestinos deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:10 am
MEX
- STL
1 stop13h 17m
Multiple Airlines
Mon 2/231:54 pm
STL
- MEX
2 stops31h 16m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2411:10 am
MEX
- STL
1 stop11h 17m
Multiple Airlines
Sun 3/110:11 pm
STL
- MEX
2 stops24h 19m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$497
This eDestinos deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:10 am
MEX
- STL
1 stop29h 46m
Multiple Airlines
Mon 3/210:11 pm
STL
- MEX
1 stop22h 59m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$475
One-way flights from Mexico City Federal District to St. LouisSearch for one-way flight options from Mexico City Federal District to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 14, 2026.
Search for one-way flight options from Mexico City Federal District to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:10 am
MEX
- STL
1 stop24h 39m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$213
This eDestinos deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:45 pm
MEX
- STL
1 stop17h 30m
Volaris
Deal found 2/13![Volaris logo]()
$216
This Cheapflightsfares deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:45 pm
MEX
- STL
1 stop17h 30m
Volaris
Deal found 2/13![Volaris logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:10 pm
MEX
- STL
2 stops31h 40m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:20 pm
MEX
- STL
3 stops58h 10m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/313:55 pm
MEX
- STL
2 stops16h 53m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$289
Find flight deals from Mexico City Federal District to St. Louis
Keep the following information in mind while searching for Mexico City Federal District to St. Louis flight deals. Data was last updated February 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $368 (Frontier) |
One-way from | $213 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $673 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mexico City Federal District to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Mexico City Federal District to St. Louis that are best for you.
Fly from
Mexico City Federal District
Fly to
St. Louis
Route
Depart
Return
Price
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Sat 5/16
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Mon 5/18
3:02 pm-10:45 am
2 stops20h 43m
$368
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Tue 5/5
10:10 pm-3:15 pm
1 stop16h 05m
Lambert-St Louis
Fri 5/8
8:12 pm-10:00 pm
2 stops26h 48m
$395
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Thu 4/23
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Tue 4/28
6:00 am-4:40 pm
1 stop11h 40m
$400
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Thu 4/23
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Tue 4/28
4:55 pm-7:45 pm
1 stop27h 50m
$401
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Fri 4/17
8:40 am-7:12 pm
1 stop9h 32m
Lambert-St Louis
Mon 4/20
3:02 pm-10:45 am
2 stops20h 43m
$403
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Fri 4/24
10:45 pm-7:12 pm
2 stops19h 27m
Lambert-St Louis
Tue 4/28
4:55 pm-7:45 pm
1 stop27h 50m
$407
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Mon 4/6
11:05 pm-3:14 pm
1 stop15h 09m
Lambert-St Louis
Mon 4/13
6:15 am-2:35 am
1 stop21h 20m
$418
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Tue 3/10
8:10 am-9:49 am
1 stop24h 39m
$213
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Mon 4/13
8:45 pm-3:15 pm
1 stop17h 30m
$216
Mexico CitySt. Louis
MEX - STL
MEXSTL
Mexico City Benito Juarez
Wed 4/15
8:45 pm-3:15 pm
1 stop17h 30m
$224
Showing 1-10 of 13 results
Best time to book a flight from Mexico City Federal District to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mexico City Federal District with our price prediction graph.
MEX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mexico City Federal District to St. Louis
MXDF-STL
MEX-STL
What is the cheapest month to book a flight from Mexico City Federal District to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Mexico City Federal District to St. Louis (average of $435). Flying from Mexico City Federal District to St. Louis in November is currently the most expensive (average of $653). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Mexico City Federal District to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus
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Alternative routes for Mexico City Federal District to St. Louis
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Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mexico City Federal District to St. Louis by cabin class
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Mexico City Federal District and St. Louis flights
Browse other Mexico City Federal District and St. Louis flight options. Last updated on February 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 14, 2026.
Top airline flying from Mexico City Federal District to St. Louis
Discover the top airline that operate flights from Mexico City Federal District to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$466 | Average$577 | FlexibilityNo cancel fee | On-time69% |