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St. Louis

$180+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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1. Tell us where you want to go

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Cheap flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/174:12 pm
MHT
-
STL
1 stop7h 52m
American Airlines
Thu 2/196:06 am
STL
-
MHT
1 stop4h 29m
American Airlines
Deal found 1/27$328
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:30 am
MHT
-
STL
1 stop7h 33m
American Airlines
Wed 6/105:30 am
STL
-
MHT
1 stop5h 04m
American Airlines
Deal found 1/28$347
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/171:20 pm
MHT
-
STL
2 stops9h 25m
Southwest
Thu 2/195:05 am
STL
-
MHT
1 stop6h 35m
Southwest
Deal found 1/27$352
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:10 am
MHT
-
STL
2 stops9h 20m
Southwest
Tue 6/3010:15 am
STL
-
MHT
2 stops6h 25m
Southwest
Deal found 1/26$357
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:35 pm
MHT
-
STL
2 stops7h 36m
United Airlines
Wed 6/1711:25 am
STL
-
MHT
2 stops11h 34m
United Airlines
Deal found 1/26$358
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:17 pm
MHT
-
STL
1 stop5h 20m
American Airlines
Mon 3/96:00 am
STL
-
MHT
1 stop4h 21m
American Airlines
Deal found 1/27$359
This Southwest deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/101:00 pm
MHT
-
STL
1 stop7h 15m
Southwest
Wed 6/176:55 am
STL
-
MHT
1 stop7h 25m
Southwest
Deal found 1/26$362
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:35 pm
MHT
-
STL
2 stops7h 36m
United Airlines
Wed 6/106:00 am
STL
-
MHT
2 stops12h 06m
United Airlines
Deal found 1/28$363
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:45 pm
MHT
-
STL
1 stop9h 50m
Southwest
Wed 6/1010:15 am
STL
-
MHT
2 stops6h 25m
Southwest
Deal found 1/28$367
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/189:00 am
MHT
-
STL
1 stop7h 30m
Southwest
Fri 3/204:45 pm
STL
-
MHT
1 stop4h 20m
Southwest
Deal found 1/27$371
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:12 pm
MHT
-
STL
1 stop7h 40m
American Airlines
Tue 3/106:00 am
STL
-
MHT
1 stop4h 25m
American Airlines
Deal found 1/26$383

Find flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$328
(American Airlines)

One-way from

$180
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$406
Provider with most accurate pricing for Manchester-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Lambert-St Louis flights.
Search Deals
From Manchester to Lambert-St Louis
Search Deals
One-way flight from Manchester to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Manchester

Fly to

St. Louis

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/23

6:15 pm-10:25 pm

1 stop5h 10m

Lambert-St Louis

Tue 6/30

5:40 am-10:50 am

1 stop4h 10m

$347

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

10:30 am-5:03 pm

1 stop7h 33m

Lambert-St Louis

Wed 6/10

5:30 am-11:34 am

1 stop5h 04m

$347

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 2/17

1:20 pm-9:45 pm

2 stops9h 25m

Lambert-St Louis

Thu 2/19

5:05 am-12:40 pm

1 stop6h 35m

$352

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 6/10

2:35 pm-9:11 pm

2 stops7h 36m

Lambert-St Louis

Wed 6/17

11:25 am-11:59 pm

2 stops11h 34m

$358

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 6/10

1:00 pm-7:15 pm

1 stop7h 15m

Lambert-St Louis

Wed 6/17

6:55 am-3:20 pm

1 stop7h 25m

$362

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

2:35 pm-9:11 pm

2 stops7h 36m

Lambert-St Louis

Wed 6/10

6:00 am-7:06 pm

2 stops12h 06m

$363

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

1:45 pm-10:35 pm

1 stop9h 50m

Lambert-St Louis

Wed 6/10

10:15 am-5:40 pm

2 stops6h 25m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 3/18

9:00 am-3:30 pm

1 stop7h 30m

Lambert-St Louis

Fri 3/20

4:45 pm-10:05 pm

1 stop4h 20m

$371

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 3/6

4:12 pm-10:52 pm

1 stop7h 40m

Lambert-St Louis

Tue 3/10

6:00 am-11:25 am

1 stop4h 25m

$383

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 5/16

5:52 pm-10:14 pm

1 stop5h 22m

$180

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 13 results
1
2

Compare providers for flights from Manchester to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $179). Flying from Manchester, New Hampshire to St. Louis in April is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 29, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Overall

8.0

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to St. Louis?

    Southwest and American Airlines can get you from Manchester, New Hampshire to St. Louis in just under 5h 10m. Your travel time can differ by up to 2h 23m. The distance between Manchester, New Hampshire and St. Louis is about 1028 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

    Currently priced at $264, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $274. Southwest is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $179). Flying from Manchester, New Hampshire to St. Louis in April is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Manchester to St. Louis

Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$264Average$444FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$274Average$400FlexibilityNo cancel feeOn-time71%

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