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St. Louis

$266+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$287
(Southwest)

Popular in

December

Cheapest in

September

Average price

$422
Provider with most accurate pricing for Manchester-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Manchester-Lambert-St Louis flights.
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From Manchester to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:36 pmMHT - STL
1 stop18h 41mMultiple Airlines
Tue 11/187:45 pmSTL - MHT
2 stops22h 11mMultiple Airlines
Deal found 10/28$334
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:44 amMHT - STL
1 stop8h 34mAmerican Airlines
Sun 12/145:02 amSTL - MHT
1 stop5h 38mAmerican Airlines
Deal found 10/27$347
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/224:04 pmMHT - STL
1 stop8h 00mAmerican Airlines
Fri 11/285:00 amSTL - MHT
1 stop5h 33mAmerican Airlines
Deal found 10/27$367
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:45 amMHT - STL
1 stop11h 45mSouthwest
Sun 12/281:00 pmSTL - MHT
1 stop10h 25mSouthwest
Deal found 10/27$428
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:36 pmMHT - STL
2 stops22h 51mMultiple Airlines
Fri 11/214:13 pmSTL - MHT
1 stop25h 43mMultiple Airlines
Deal found 10/28$434
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:36 pmMHT - STL
1 stop18h 41mMultiple Airlines
Thu 11/209:54 pmSTL - MHT
2 stops44h 02mMultiple Airlines
Deal found 10/28$441
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:00 amMHT - STL
1 stop8h 13mAmerican Airlines
Thu 11/206:02 amSTL - MHT
1 stop4h 37mAmerican Airlines
Deal found 10/28$447
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:50 pmMHT - STL
1 stop6h 30mSouthwest
Fri 11/282:30 pmSTL - MHT
2 stops8h 35mSouthwest
Deal found 10/27$448
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:36 pmMHT - STL
1 stop18h 41mMultiple Airlines
Sat 11/229:52 amSTL - MHT
2 stops23h 45mMultiple Airlines
Deal found 10/28$452
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:29 amMHT - STL
1 stop7h 09mAmerican Airlines
Wed 11/196:04 pmSTL - MHT
1 stop4h 44mAmerican Airlines
Deal found 10/28$457
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:36 pmMHT - STL
1 stop21h 42mMultiple Airlines
Tue 11/187:45 pmSTL - MHT
2 stops22h 11mMultiple Airlines
Deal found 10/28$458
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/112:27 pmMHT - STL
2 stops10h 15mUnited Airlines
Tue 11/188:25 amSTL - MHT
1 stop4h 22mUnited Airlines
Deal found 10/28$462

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Manchester

Fly to

St. Louis

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 12/9

7:05 am-3:50 pm

1 stop9h 45m

Lambert-St Louis

Wed 12/10

6:05 am-12:20 pm

1 stop5h 15m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 2/11

2:17 pm-9:13 pm

2 stops7h 56m

Lambert-St Louis

Sun 2/15

8:30 am-1:58 pm

1 stop4h 28m

$289

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 12/10

12:55 pm-9:00 pm

2 stops9h 05m

Lambert-St Louis

Thu 12/11

1:50 pm-9:05 pm

1 stop6h 15m

$292

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/21

2:17 pm-11:59 pm

2 stops10h 42m

Lambert-St Louis

Sat 1/24

9:57 am-6:51 pm

2 stops7h 54m

$297

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/21

2:17 pm-11:59 pm

2 stops10h 42m

Lambert-St Louis

Sun 1/25

8:05 am-6:51 pm

2 stops9h 46m

$357

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 2/24

6:00 am-12:27 pm

1 stop7h 27m

Lambert-St Louis

Wed 2/25

4:01 pm-12:06 am

1 stop7h 05m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 11/22

4:04 pm-11:04 pm

1 stop8h 00m

Lambert-St Louis

Fri 11/28

5:00 am-11:33 am

1 stop5h 33m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 11/13

6:00 am-1:13 pm

1 stop8h 13m

$266

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 11/10

2:27 pm-7:16 pm

1 stop5h 49m

$597

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sun 11/30

9:30 am-11:44 pm

2 stops15h 14m

$730

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Compare providers for flights from Manchester to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $107). Flying from Manchester, New Hampshire to St. Louis in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to STL?

Find hourly flight availability from Manchester to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Manchester, New Hampshire to St. Louis in the evening. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Crew

8.6

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to St. Louis?

    Southwest and United Airlines can get you from Manchester, New Hampshire to St. Louis in just under 7h 56m. Your travel time can differ by up to 1h 49m. The distance between Manchester, New Hampshire and St. Louis is about 1028 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

    Currently priced at $264, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $278. Southwest is currently priced 36% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $107). Flying from Manchester, New Hampshire to St. Louis in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Manchester to St. Louis

Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$264Average$445FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$278Average$401FlexibilityNo cancel feeOn-time71%

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