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$149+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/5. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$267
(American Airlines)

One-way from

$149
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$386
From Manchester to Lambert-St Louis
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One-way flight from Manchester to Lambert-St Louis
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Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:59 pmMHT - STL
1 stop4h 54mAmerican Airlines
Tue 10/76:08 pmSTL - MHT
1 stop4h 40mAmerican Airlines
Deal found 7/28$267
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/33:45 pmMHT - STL
1 stop7h 40mSouthwest
Tue 10/78:55 amSTL - MHT
2 stops7h 05mSouthwest
Deal found 7/28$312
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/181:30 pmMHT - STL
2 stops11h 14mUnited Airlines
Mon 9/227:04 pmSTL - MHT
2 stops14h 38mUnited Airlines
Deal found 7/29$553

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Manchester

Fly to

St. Louis

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 10/3

5:59 pm-9:53 pm

1 stop4h 54m

Lambert-St Louis

Tue 10/7

6:08 pm-11:48 pm

1 stop4h 40m

$267

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 10/3

3:45 pm-10:25 pm

1 stop7h 40m

Lambert-St Louis

Tue 10/7

8:55 am-5:00 pm

2 stops7h 05m

$312

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 9/18

1:30 pm-11:44 pm

2 stops11h 14m

Lambert-St Louis

Mon 9/22

7:04 pm-10:42 am

2 stops14h 38m

$553

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 9/5

5:59 pm-10:05 pm

1 stop5h 06m

$149

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 10/17

5:25 am-12:40 pm

2 stops8h 15m

$184

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 9/5

1:30 pm-2:19 pm

2 stops25h 49m

$222

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 10/17

9:59 am-5:55 pm

3 stops32h 56m

$301

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $311). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to STL?

Find hourly flight availability from Manchester to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Manchester, New Hampshire to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Manchester, New Hampshire to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Comfort

8.0

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

    Currently priced at $267, American Airlines will fly you from Manchester, New Hampshire to St. Louis and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and United Airlines - these airlines can fly you to your destination from $312 and $553, respectively. American Airlines is currently priced 36% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Manchester, New Hampshire to St. Louis one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $149. Southwest flights start at $184 while deals on United Airlines start at $222 one-way.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $311). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Festus
Farmington

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Top 2 airlines flying from Manchester to St. Louis

Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$264Average$422FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$311Average$408FlexibilityNo cancel feeOn-time71%

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