How long is the flight from Manchester, New Hampshire to St. Louis?

American Airlines and Southwest can get you from Manchester, New Hampshire to St. Louis in just under 6h 15m. Your travel time can differ by up to 3h. The distance between Manchester, New Hampshire and St. Louis is about 1028 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

Currently priced at $264, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $274. Southwest is currently priced 36% below the average price you’ll pay for this route.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Most accurate provider : When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Manchester to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

Can I find deals for business class flights from Manchester to St. Louis?

Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$287+ Flights from Manchester, NH to St. Louis

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Manchester to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Fri 12/264:40 pmMHT - STL

1 stop8h 15mAmerican Airlines

Tue 12/306:02 amSTL - MHT

1 stop4h 32mAmerican Airlines

Deal found 12/11

$487

Sat 12/206:00 amMHT - STL

1 stop14h 30mAmerican Airlines

Fri 1/26:02 amSTL - MHT

1 stop16h 32mAmerican Airlines

Deal found 12/11

$619

Sat 12/202:23 pmMHT - STL

2 stops8h 20mUnited Airlines

Fri 1/28:15 amSTL - MHT

1 stop4h 33mUnited Airlines

Deal found 12/11

$657

Fri 12/267:26 pmMHT - STL

2 stops28h 17mUnited Airlines

Tue 12/308:15 amSTL - MHT

1 stop4h 33mUnited Airlines

Deal found 12/11

$785

Thu 12/114:40 pmMHT - STL

1 stop17h 52mAmerican Airlines

Sun 12/147:12 amSTL - MHT

1 stop14h 36mAmerican Airlines

Deal found 12/11

$813

Thu 12/252:23 pmMHT - STL

1 stop5h 59mUnited Airlines

Mon 12/296:35 pmSTL - MHT

2 stops18h 13mUnited Airlines

Deal found 12/10

$834

Mon 12/155:35 pmMHT - STL

1 stop5h 45mSouthwest

Wed 12/175:10 amSTL - MHT

1 stop8h 45mSouthwest

Deal found 12/10

$887

Best flights from Manchester to St. Louis
Discover carefully curated flight deals from Manchester to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Wed 1/712:08 pmMHT - STL

1 stop6h 15mAmerican Airlines

Wed 1/149:33 amSTL - MHT

1 stop5h 05mAmerican Airlines

Deal found 12/10

$287

Wed 1/712:45 pmMHT - STL

2 stops9h 15mSouthwest

Sat 1/107:40 amSTL - MHT

2 stops8h 50mSouthwest

Deal found 12/11

$357

Wed 1/72:17 pmMHT - STL

1 stop6h 10mUnited Airlines

Wed 1/1412:44 pmSTL - MHT

1 stop5h 07mUnited Airlines

Deal found 12/10

$391

Wed 1/712:08 pmMHT - STL

1 stop6h 15mAmerican Airlines

Sat 1/103:54 pmSTL - MHT

1 stop7h 05mAmerican Airlines

Deal found 12/11

$287

Thu 1/85:00 amMHT - STL

1 stop7h 15mSouthwest

Thu 1/155:05 amSTL - MHT

1 stop6h 35mSouthwest

Deal found 12/10

$359

Fri 2/65:01 pmMHT - STL

1 stop5h 50mAmerican Airlines

Tue 2/103:54 pmSTL - MHT

1 stop6h 52mAmerican Airlines

Deal found 12/11

$347

Tue 1/132:17 pmMHT - STL

2 stops10h 42mUnited Airlines

Wed 1/1412:44 pmSTL - MHT

1 stop5h 07mUnited Airlines

Deal found 12/10

$396

Mon 4/275:06 pmMHT - STL

1 stop6h 19mAmerican Airlines

Wed 4/2910:48 amSTL - MHT

1 stop4h 47mAmerican Airlines

Deal found 12/10

$377

Last-minute flights from Manchester to St. Louis
Discover last-minute flight deals from Manchester to St. Louis. Data last updated December 12, 2025 and is based on user searches.

Wed 1/712:08 pmMHT - STL

1 stop6h 15mAmerican Airlines

Sat 1/103:54 pmSTL - MHT

1 stop7h 05mAmerican Airlines

Deal found 12/11

$287

Wed 1/712:45 pmMHT - STL

2 stops9h 15mSouthwest

Sat 1/106:40 amSTL - MHT

1 stop6h 50mSouthwest

Deal found 12/11

$316

Wed 1/72:17 pmMHT - STL

1 stop6h 10mUnited Airlines

Wed 1/1412:44 pmSTL - MHT

1 stop5h 07mUnited Airlines

Deal found 12/10

$391

Thu 1/85:00 amMHT - STL

1 stop7h 15mSouthwest

Thu 1/155:05 amSTL - MHT

1 stop6h 35mSouthwest

Deal found 12/10

$359

Fri 1/94:06 pmMHT - STL

1 stop7h 38mAmerican Airlines

Fri 1/169:33 amSTL - MHT

1 stop5h 05mAmerican Airlines

Deal found 12/10

$407

Tue 1/132:17 pmMHT - STL

2 stops10h 42mUnited Airlines

Wed 1/1412:44 pmSTL - MHT

1 stop5h 07mUnited Airlines

Deal found 12/10

$396

One-way flights from Manchester to St. Louis
Search for one-way flight options from Manchester to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Fri 12/197:26 pmMHT - STL

2 stops20h 00mUnited Airlines

Deal found 12/9

$614

Thu 12/182:23 pmMHT - STL

1 stop20h 45mUnited Airlines

Deal found 12/9

$780

Find flight deals from Manchester to St. Louis

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$287 (American Airlines)
Popular in	December
Cheapest in	September
Average price	$511

Provider with most accurate pricing for Manchester-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Manchester-Lambert-St Louis flights.

Search Deals

From Manchester to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

12:08 pm-5:23 pm

1 stop6h 15m

Lambert-St Louis

Wed 1/14

9:33 am-3:38 pm

1 stop5h 05m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

12:08 pm-5:23 pm

1 stop6h 15m

Lambert-St Louis

Sat 1/10

3:54 pm-11:59 pm

1 stop7h 05m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 2/6

5:01 pm-9:51 pm

1 stop5h 50m

Lambert-St Louis

Tue 2/10

3:54 pm-11:46 pm

1 stop6h 52m

$347

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

12:45 pm-9:00 pm

2 stops9h 15m

Lambert-St Louis

Sat 1/10

7:40 am-5:30 pm

2 stops8h 50m

$357

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 1/8

5:00 am-11:15 am

1 stop7h 15m

Lambert-St Louis

Thu 1/15

5:05 am-12:40 pm

1 stop6h 35m

$359

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 4/27

5:06 pm-10:25 pm

1 stop6h 19m

Lambert-St Louis

Wed 4/29

10:48 am-4:35 pm

1 stop4h 47m

$377

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 1/7

2:17 pm-7:27 pm

1 stop6h 10m

Lambert-St Louis

Wed 1/14

12:44 pm-6:51 pm

1 stop5h 07m

$391

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 1/13

2:17 pm-11:59 pm

2 stops10h 42m

Lambert-St Louis

Wed 1/14

12:44 pm-6:51 pm

1 stop5h 07m

$396

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 5/13

2:30 pm-11:56 pm

2 stops10h 26m

$345

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 12/20

7:26 pm-12:27 pm

2 stops18h 01m

$614

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 12 results

Compare providers for flights from Manchester to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $107). Flying from Manchester, New Hampshire to St. Louis in April is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to STL?

A simple way to save on the total cost of your ticket is to fly from Manchester, New Hampshire to St. Louis in the evening. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Manchester, New Hampshire to St. Louis?
American Airlines and Southwest can get you from Manchester, New Hampshire to St. Louis in just under 6h 15m. Your travel time can differ by up to 3h. The distance between Manchester, New Hampshire and St. Louis is about 1028 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?
Currently priced at $264, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $274. Southwest is currently priced 36% below the average price you’ll pay for this route.
Can I find deals for flights from Manchester to St. Louis that include hotel bookings?
Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Manchester to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.
Can I find deals for business class flights from Manchester to St. Louis?
Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $107). Flying from Manchester, New Hampshire to St. Louis in April is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Edwardsville

O'Fallon

Fairview Heights

Maryland Heights

Collinsville

Swansea

Eureka

Glencoe

St. Peters

Chesterfield

Alton

Farmington

Festus

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Manchester to St. Louis

Boston to Kansas City flights

Boston to St. Louis flights

Boston to Springfield flights

Manchester to Kansas City flights

Portland to Kansas City flights

Portland to Springfield flights

Manchester to Springfield flights

Portland to St. Louis flights

Boston to Columbia flights

Boston to Joplin flights

Manchester to Joplin flights

Worcester to Springfield flights

Complete your trip

St. Louis car rentals

Lambert-St Louis Airport car rentals

Springfield Capital Airport car rentals

Belleville Airport car rentals

Marion Williamson County Airport car rentals

Kansas City car rentals

Springfield car rentals

Joplin car rentals

Columbia car rentals

Fort Leonard Wood car rentals

Downtown car rentals

The Hill car rentals

Other flights to St. Louis

Top 2 airlines flying from Manchester to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Southwest	Cheapest$264	Average$444	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$274	Average$393	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$287+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Manchester to St. Louis with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. LouisExplore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Manchester to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Compare providers for flights from Manchester to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in December.

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

What is the cheapest time of day to fly from MHT to STL?

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Manchester, New Hampshire to St. Louis?

What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

How can I find direct flights from Manchester to St. Louis?

Can I find deals for business class flights from Manchester to St. Louis?

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Traveling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Manchester to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Manchester to St. Louis

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.