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$144+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$287
(Southwest)

One-way from

$144
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$338
From Manchester to Lambert-St Louis
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One-way flight from Manchester to Lambert-St Louis
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Highest demand for flights based on searches. 8% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1312:40 pmMHT - STL
1 stop7h 50mSouthwest
Wed 12/176:05 amSTL - MHT
1 stop5h 15mSouthwest
Deal found 9/16$287
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:43 amMHT - STL
1 stop8h 34mAmerican Airlines
Sat 11/88:43 amSTL - MHT
1 stop7h 06mAmerican Airlines
Deal found 9/15$307
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:00 amMHT - STL
1 stop6h 25mSouthwest
Sat 11/812:20 pmSTL - MHT
2 stops8h 30mSouthwest
Deal found 9/15$312
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:00 amMHT - STL
1 stop5h 10mSouthwest
Fri 10/244:55 pmSTL - MHT
1 stop6h 25mSouthwest
Deal found 9/17$317
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/147:34 pmMHT - STL
1 stop5h 20mAmerican Airlines
Tue 10/214:45 pmSTL - MHT
1 stop5h 12mAmerican Airlines
Deal found 9/15$318
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/253:05 pmMHT - STL
1 stop6h 25mSouthwest
Tue 10/2812:00 pmSTL - MHT
2 stops9h 55mSouthwest
Deal found 9/16$322
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:00 amMHT - STL
1 stop4h 56mAmerican Airlines
Wed 10/295:53 pmSTL - MHT
1 stop4h 58mAmerican Airlines
Deal found 9/15$347
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:30 pmMHT - STL
2 stops8h 05mSouthwest
Wed 12/1712:45 pmSTL - MHT
2 stops8h 25mSouthwest
Deal found 9/16$357
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/265:05 amMHT - STL
1 stop7h 55mSouthwest
Wed 10/2912:00 pmSTL - MHT
2 stops9h 55mSouthwest
Deal found 9/15$358

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Manchester

Fly to

St. Louis

Route

Depart

Return

Price

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 12/13

12:40 pm-7:30 pm

1 stop7h 50m

Lambert-St Louis

Wed 12/17

6:05 am-12:20 pm

1 stop5h 15m

$287

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 10/21

5:00 am-9:10 am

1 stop5h 10m

Lambert-St Louis

Fri 10/24

4:55 pm-12:20 am

1 stop6h 25m

$317

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Sat 10/25

3:05 pm-8:30 pm

1 stop6h 25m

Lambert-St Louis

Tue 10/28

1:15 pm-9:20 pm

1 stop7h 05m

$317

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Fri 12/12

5:20 pm-11:15 pm

1 stop6h 55m

Lambert-St Louis

Wed 12/17

12:45 pm-10:10 pm

2 stops8h 25m

$322

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 11/24

5:20 pm-11:15 pm

1 stop6h 55m

Lambert-St Louis

Mon 12/1

9:45 pm-8:10 am

2 stops9h 25m

$352

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 2/24

5:10 pm-10:44 pm

1 stop6h 34m

Lambert-St Louis

Wed 2/25

6:40 am-2:59 pm

1 stop7h 19m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 10/23

5:25 am-11:30 am

1 stop7h 05m

Lambert-St Louis

Sun 10/26

6:10 am-12:10 pm

1 stop5h 00m

$367

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 10/2

7:03 am-1:23 pm

1 stop7h 20m

$195

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 11/4

2:27 pm-10:45 pm

2 stops9h 18m

$234

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 9/23

7:19 am-1:09 pm

1 stop6h 50m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 13 results
1
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Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $311). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to STL?

Find hourly flight availability from Manchester to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

A simple way to save on the total cost of your ticket is to fly from Manchester, New Hampshire to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Manchester, New Hampshire to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to St. Louis?

    Southwest can get you from Manchester, New Hampshire to St. Louis in just under 7h 50m. Your travel time can differ by up to . The distance between Manchester, New Hampshire and St. Louis is about 1028 mi.

  • What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

    Currently priced at $264, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $278. Southwest is currently priced 37% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $311). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Manchester to St. Louis

Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$264Average$433FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$278Average$408FlexibilityNo cancel feeOn-time71%

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