$170+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Sep 20 — Sep 271
Round-trip
1 adult, Economy
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Find cheap flights from Manchester to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Manchester to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Manchester to St. LouisExplore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:15 pm -
1 stop4h 30m
Tue 9/221:40 pm -
1 stop7h 15m
Deal found 8/16![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:46 pm -
2 stops9h 52m
Tue 9/228:00 am -
2 stops10h 00m
Deal found 8/16![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:02 pm -
1 stop5h 25m
Fri 9/255:45 pm -
1 stop4h 46m
Deal found 8/16![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:35 am -
2 stops7h 35m
Sat 9/265:45 am -
1 stop4h 30m
Deal found 8/20![Southwest logo]()
$363
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:45 am -
2 stops8h 15m
Tue 10/278:30 am -
2 stops5h 45m
Deal found 8/20![Southwest logo]()
$368
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:06 am -
1 stop6h 49m
Mon 9/76:00 am -
1 stop4h 42m
Deal found 8/17![American Airlines logo]()
$392
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:46 pm -
1 stop5h 25m
Sat 9/58:00 am -
2 stops10h 00m
Deal found 8/17![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop5h 52m
Sun 9/135:45 pm -
1 stop4h 46m
Deal found 8/17![American Airlines logo]()
$398
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
2 stops10h 30m
Fri 9/252:25 pm -
1 stop6h 30m
Deal found 8/16![Southwest logo]()
$409
Best flights from Manchester to St. LouisDiscover carefully curated flight deals from Manchester to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
Discover carefully curated flight deals from Manchester to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:35 am -
2 stops7h 35m
Sat 9/265:45 am -
1 stop4h 30m
Deal found 8/20![Southwest logo]()
$363
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:25 am -
2 stops8h 41m
Sat 9/58:30 am -
2 stops9h 30m
Deal found 8/17![United Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:33 am -
1 stop7h 32m
Sun 9/205:45 pm -
1 stop4h 46m
Deal found 8/20![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:05 am -
2 stops10h 50m
Sun 9/67:35 am -
2 stops8h 15m
Deal found 8/18![Southwest logo]()
$447
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:25 am -
2 stops10h 51m
Mon 10/51:29 pm -
2 stops9h 27m
Deal found 8/19![United Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/102:38 pm -
2 stops8h 46m
Wed 11/111:00 pm -
1 stop9h 59m
Deal found 8/19![United Airlines logo]()
$503
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/268:45 am -
1 stop8h 05m
Mon 1/410:15 am -
1 stop6h 40m
Deal found 8/16![Southwest logo]()
$532
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/91:30 pm -
2 stops26h 00m
Sat 12/127:33 am -
2 stops10h 26m
Deal found 8/17![United Airlines logo]()
$508
Last-minute flights from Manchester to St. LouisDiscover last-minute flight deals from Manchester to St. Louis. Data last updated August 21, 2026 and is based on user searches.
Discover last-minute flight deals from Manchester to St. Louis. Data last updated August 21, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:46 pm -
1 stop5h 25m
Sat 9/58:00 am -
2 stops10h 00m
Deal found 8/17![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop5h 52m
Sun 9/135:45 pm -
1 stop4h 46m
Deal found 8/17![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:06 am -
1 stop6h 49m
Mon 9/76:00 am -
1 stop4h 42m
Deal found 8/17![American Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:15 pm -
1 stop4h 30m
Tue 9/221:40 pm -
1 stop7h 15m
Deal found 8/16![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:46 pm -
2 stops9h 52m
Tue 9/228:00 am -
2 stops10h 00m
Deal found 8/16![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1810:33 am -
1 stop7h 32m
Sun 9/205:45 pm -
1 stop4h 46m
Deal found 8/20![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:35 am -
2 stops7h 35m
Sat 9/265:45 am -
1 stop4h 30m
Deal found 8/20![Southwest logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:02 pm -
1 stop5h 25m
Fri 9/255:45 pm -
1 stop4h 46m
Deal found 8/16![American Airlines logo]()
$362
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
2 stops10h 30m
Fri 9/252:25 pm -
1 stop6h 30m
Deal found 8/16![Southwest logo]()
$409
One-way flights from Manchester to St. LouisSearch for one-way flight options from Manchester to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
Search for one-way flight options from Manchester to St. Louis. Find affordable one-way fares based on user searches. Data last updated August 21, 2026.
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:25 pm -
1 stop4h 45m
Deal found 8/18![Southwest logo]()
$170
This Southwest deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:35 am -
2 stops6h 45m
Deal found 8/17![Southwest logo]()
$175
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:46 pm -
2 stops9h 52m
Deal found 8/18![United Airlines logo]()
$187
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:40 am -
1 stop6h 55m
Deal found 8/20![Southwest logo]()
$193
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:25 am -
2 stops13h 11m
Deal found 8/20![United Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:29 pm -
3 stops29h 53m
Deal found 8/16![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:18 pm -
2 stops30h 36m
Deal found 8/20![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:24 pm -
3 stops25h 46m
Deal found 8/18![Multiple Airlines logo]()
$218
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:25 am -
1 stop6h 05m
Deal found 8/18![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:18 pm -
3 stops49h 52m
Deal found 8/19![Multiple Airlines logo]()
$222
This Southwest deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:35 pm -
1 stop5h 00m
Deal found 8/16![Southwest logo]()
$223
Find flight deals from Manchester to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (Southwest) |
One-way from | $170 (Southwest) |
Popular in | March |
Cheapest in | November |
Average price | $470 |
Cheapflights Fare Finder
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Tue 9/22
5:35 am-12:10 pm
2 stops7h 35m
Lambert-St Louis
Sat 9/26
5:45 am-11:15 am
1 stop4h 30m
$363
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Tue 9/1
9:25 am-5:06 pm
2 stops8h 41m
Lambert-St Louis
Sat 9/5
8:30 am-7:00 pm
2 stops9h 30m
$402
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Fri 9/18
10:33 am-5:05 pm
1 stop7h 32m
Lambert-St Louis
Sun 9/20
5:45 pm-11:31 pm
1 stop4h 46m
$411
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Wed 9/2
10:05 am-7:55 pm
2 stops10h 50m
Lambert-St Louis
Sun 9/6
7:35 am-4:50 pm
2 stops8h 15m
$447
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Tue 9/1
9:25 am-7:16 pm
2 stops10h 51m
Lambert-St Louis
Mon 10/5
1:29 pm-11:56 pm
2 stops9h 27m
$496
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Tue 11/10
2:38 pm-10:24 pm
2 stops8h 46m
Lambert-St Louis
Wed 11/11
1:00 pm-11:59 pm
1 stop9h 59m
$503
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Wed 12/9
1:30 pm-2:30 pm
2 stops26h 00m
Lambert-St Louis
Sat 12/12
7:33 am-6:59 pm
2 stops10h 26m
$508
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Sat 12/26
8:45 am-3:50 pm
1 stop8h 05m
Lambert-St Louis
Mon 1/4
10:15 am-5:55 pm
1 stop6h 40m
$532
Cheapest one-way
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Thu 9/17
6:25 pm-10:10 pm
1 stop4h 45m
$170
ManchesterSt. Louis
MHT Manchester - STL Lambert-St Louis
MHTSTL
Manchester
Mon 9/14
6:25 pm-10:10 pm
1 stop4h 45m
$170
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Manchester to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Manchester to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
MHT-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Manchester to St. Louis
What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?
Currently, November is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $356). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $802). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Manchester, New Hampshire to St. Louis?
Airfare is below average for this route at the moment.
Manchester, New Hampshire to St. Louis flights typically cost between $374 and $524 in September.The cheapest round-trip price found within the last 5 days was $339 on Southwest (Sep 15-Sep 22).
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 21, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Overall
8.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
Fairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Glencoe
Chesterfield
Farmington
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Manchester and St. Louis flights
Browse other Manchester and St. Louis flight options. Last updated on August 21, 2026.
Other flights from Manchester
Browse through other flights departing from Manchester. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 21, 2026.
Top 2 airlines flying from Manchester to St. Louis
Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$274 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$436 | FlexibilityNo cancel fee | On-time63% |