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St. Louis

$154+ Cheap flights from Manchester, NH to St. Louis (MHT - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — STL
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Manchester to St. Louis

Cheapest flights from Manchester to St. Louis
Explore the most affordable flight options available from Manchester to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:12 pm
MHT
-
STL
1 stop5h 29m
American Airlines
Tue 4/285:51 am
STL
-
MHT
1 stop4h 51m
American Airlines
Deal found 3/20$307
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
MHT
-
STL
1 stop5h 52m
United Airlines
Tue 4/217:45 am
STL
-
MHT
2 stops10h 11m
United Airlines
Deal found 3/18$312
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
MHT
-
STL
2 stops7h 43m
United Airlines
Tue 4/217:45 am
STL
-
MHT
2 stops10h 11m
United Airlines
Deal found 3/18$317
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:59 pm
MHT
-
STL
1 stop6h 55m
American Airlines
Wed 6/36:00 am
STL
-
MHT
1 stop4h 50m
American Airlines
Deal found 3/17$327
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:10 am
MHT
-
STL
1 stop7h 05m
Southwest
Wed 6/32:30 pm
STL
-
MHT
2 stops7h 00m
Southwest
Deal found 3/17$332
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:41 pm
MHT
-
STL
1 stop7h 05m
American Airlines
Wed 4/296:00 am
STL
-
MHT
1 stop4h 36m
American Airlines
Deal found 3/20$337
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
MHT
-
STL
1 stop5h 52m
United Airlines
Mon 4/209:10 am
STL
-
MHT
2 stops8h 46m
United Airlines
Deal found 3/18$342
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:30 pm
MHT
-
STL
2 stops7h 43m
United Airlines
Mon 4/207:45 am
STL
-
MHT
2 stops10h 11m
United Airlines
Deal found 3/18$347
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:46 am
MHT
-
STL
1 stop6h 01m
American Airlines
Sun 5/245:00 pm
STL
-
MHT
1 stop5h 46m
American Airlines
Deal found 3/20$367
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:30 pm
MHT
-
STL
1 stop5h 52m
United Airlines
Wed 4/229:10 am
STL
-
MHT
2 stops8h 46m
United Airlines
Deal found 3/18$370

Find flight deals from Manchester to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(American Airlines)

One-way from

$154
(United Airlines)

Popular in

March

Cheapest in

February

Average price

$502
Provider with most accurate pricing for Manchester-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Lambert-St Louis flights.
Search Deals
From Manchester to Lambert-St Louis
Search Deals
One-way flight from Manchester to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Manchester to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

9:10 am-3:15 pm

1 stop7h 05m

Lambert-St Louis

Wed 6/3

2:30 pm-10:30 pm

2 stops7h 00m

$332

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 4/15

2:30 pm-9:13 pm

2 stops7h 43m

Lambert-St Louis

Mon 4/20

7:45 am-6:56 pm

2 stops10h 11m

$347
Quickest round-trip

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 6/3

12:45 pm-8:00 pm

2 stops8h 15m

Lambert-St Louis

Sun 6/14

6:40 am-11:55 am

1 stop4h 15m

$382

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Thu 4/23

7:10 pm-10:45 pm

1 stop4h 35m

Lambert-St Louis

Sun 4/26

8:00 pm-8:30 am

1 stop11h 30m

$402

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 5/5

2:36 pm-11:57 pm

2 stops10h 21m

Lambert-St Louis

Wed 5/6

7:45 am-6:56 pm

2 stops10h 11m

$407

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Mon 4/20

4:40 pm-10:45 pm

2 stops7h 05m

Lambert-St Louis

Mon 4/27

7:45 pm-8:05 am

1 stop11h 20m

$458

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 4/15

2:30 pm-7:22 pm

1 stop5h 52m

Lambert-St Louis

Tue 4/28

7:45 am-6:56 pm

2 stops10h 11m

$468

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 3/31

2:30 pm-11:57 pm

2 stops10h 27m

Lambert-St Louis

Sat 4/4

7:45 am-6:56 pm

2 stops10h 11m

$517
Cheapest one-way
Quickest one-way

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Wed 4/22

3:45 pm-9:05 pm

1 stop6h 20m

$154

ManchesterSt. Louis

MHT - STL

MHTSTL

Manchester

Tue 6/2

2:37 pm-11:36 pm

2 stops9h 59m

$169

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Manchester to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to St. Louis in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to St. Louis

What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $179). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Manchester, New Hampshire to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated March 22, 2026.
Get a feel of what it's like to fly with Southwest and American Airlines from Manchester to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,488 reviews
Southwest
8.0
Very good
4,324 reviews

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Manchester to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to St. Louis?

    Southwest and United Airlines can get you from Manchester, New Hampshire to St. Louis in just under 7h 05m. Your travel time can differ by up to 38m. The distance between Manchester, New Hampshire and St. Louis is about 1028 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Manchester, New Hampshire to St. Louis round-trip?

    Currently priced at $200, Southwest will fly you from Manchester, New Hampshire to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $278. Southwest is currently priced 48% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to St. Louis that include hotel bookings?

    Yes. In addition to deals on Manchester to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to St. Louis.

  • Can I find deals for business class flights from Manchester to St. Louis?

    Yes. Cheapflights offers flight deals from Manchester to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to St. Louis (average of $179). Flying from Manchester, New Hampshire to St. Louis in March is currently the most expensive (average of $362). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Manchester to St. Louis

Discover the top 2 airlines that operate flights from Manchester to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$200Average$446FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$278Average$387FlexibilityNo cancel feeOn-time71%

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