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$136+ Cheap flights from Greenville to St. Louis (GSP - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Greenville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$223
(Southwest)

One-way from

$136
(American Airlines)

Popular in

May

Cheapest in

October

Average price

$319
From Greenville to Lambert-St Louis
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One-way flight from Greenville to Lambert-St Louis
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Highest demand for flights based on searches. 6% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Greenville to St. Louis

Cheapest flights from Greenville to St. Louis
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:45 amGSP - STL
1 stop4h 05mSouthwest
Wed 9/101:35 pmSTL - GSP
1 stop3h 30mSouthwest
Deal found 8/14$223
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:04 amGSP - STL
1 stop5h 39mDelta
Mon 10/136:52 pmSTL - GSP
1 stop4h 02mDelta
Deal found 8/14$237
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/181:50 pmGSP - STL
1 stop6h 45mSouthwest
Sun 9/215:35 amSTL - GSP
1 stop7h 00mSouthwest
Deal found 8/13$254
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:30 amGSP - STL
1 stop7h 15mSouthwest
Fri 9/269:40 amSTL - GSP
2 stops7h 25mSouthwest
Deal found 8/13$259
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:30 pmGSP - STL
1 stop5h 52mAmerican Airlines
Sun 9/76:05 amSTL - GSP
1 stop3h 51mAmerican Airlines
Deal found 8/14$271
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:38 pmGSP - STL
1 stop4h 29mAmerican Airlines
Thu 9/186:00 amSTL - GSP
1 stop5h 28mAmerican Airlines
Deal found 8/13$273
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:04 pmGSP - STL
1 stop4h 50mAmerican Airlines
Sun 10/195:11 amSTL - GSP
1 stop7h 10mAmerican Airlines
Deal found 8/14$274
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/156:13 pmGSP - STL
1 stop6h 11mDelta
Thu 9/187:10 amSTL - GSP
1 stop5h 18mDelta
Deal found 8/14$288
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/910:25 amGSP - STL
1 stop3h 45mSouthwest
Thu 9/119:05 amSTL - GSP
2 stops8h 00mSouthwest
Deal found 8/13$293

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Greenville

Fly to

St. Louis

Route

Depart

Return

Price

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 9/9

6:33 pm-10:50 pm

1 stop5h 17m

Lambert-St Louis

Thu 9/11

5:18 am-11:57 am

1 stop5h 39m

$223

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 9/4

10:45 am-1:50 pm

1 stop4h 05m

Lambert-St Louis

Wed 9/10

1:35 pm-6:05 pm

1 stop3h 30m

$223

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 10/9

10:04 am-2:43 pm

1 stop5h 39m

Lambert-St Louis

Mon 10/13

6:52 pm-11:54 pm

1 stop4h 02m

$237

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 9/18

1:50 pm-7:35 pm

1 stop6h 45m

Lambert-St Louis

Sun 9/21

5:35 am-1:35 pm

1 stop7h 00m

$254

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 10/12

5:30 am-8:05 am

1 stop3h 35m

Lambert-St Louis

Mon 10/13

6:52 pm-11:54 pm

1 stop4h 02m

$254

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 9/24

9:30 am-3:45 pm

1 stop7h 15m

Lambert-St Louis

Fri 9/26

1:50 pm-6:05 pm

1 stop3h 15m

$254

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Wed 9/24

5:30 pm-10:22 pm

1 stop5h 52m

Lambert-St Louis

Sun 9/28

5:27 am-10:33 am

1 stop4h 06m

$259

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Fri 9/5

5:30 pm-10:22 pm

1 stop5h 52m

Lambert-St Louis

Sun 9/7

6:05 am-10:56 am

1 stop3h 51m

$271

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Mon 9/15

7:38 pm-11:07 pm

1 stop4h 29m

Lambert-St Louis

Thu 9/18

6:00 am-12:28 pm

1 stop5h 28m

$273

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 10/5

5:06 am-8:05 am

1 stop3h 59m

$136

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 11 results
1
2

Best time to book a flight from Greenville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to St. Louis

What is the cheapest month to book a flight from Greenville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $311). Flying from Greenville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to STL?

Find hourly flight availability from Greenville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Greenville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the evening.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 14, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Greenville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Crew

8.6

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Greenville to St. Louis round-trip?

    According to our current data, Delta ($251), American Airlines ($281), and Southwest ($286) offers the cheapest pricing from Greenville to St. Louis. Delta is priced at 33% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Greenville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Greenville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to St. Louis.

  • Can I find deals for business class flights from Greenville to St. Louis?

    Yes. Cheapflights offers flight deals from Greenville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $311). Flying from Greenville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Farmington
Festus

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Top 3 airlines flying from Greenville to St. Louis

Discover the top 3 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$251Average$366FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$281Average$409FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$346FlexibilityNo cancel feeOn-time63%

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