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$184+ Cheap flights from Greenville to St. Louis (GSP - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Dec 16 — Dec 231
Tue 12/16
Tue 12/23
1 adult, Economy
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Find flight deals from Greenville to St. Louis

Cheapest flights from Greenville to St. Louis
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 16, 2025.

This Southwest deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:05 pmGSP - STL
1 stop6h 55mSouthwest
Tue 12/95:45 amSTL - GSP
1 stop7h 45mSouthwest
Deal found 11/16$342
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:05 amGSP - STL
1 stop7h 35mUnited Airlines
Tue 12/912:55 pmSTL - GSP
2 stops10h 04mUnited Airlines
Deal found 11/16$347
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/77:25 amGSP - STL
1 stop7h 28mDelta
Thu 12/117:02 pmSTL - GSP
1 stop3h 38mDelta
Deal found 11/13$354
This Southwest deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:00 amGSP - STL
2 stops9h 40mSouthwest
Thu 12/115:45 amSTL - GSP
1 stop7h 45mSouthwest
Deal found 11/13$359
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:59 pmGSP - STL
1 stop4h 43mDelta
Fri 1/27:02 pmSTL - GSP
1 stop3h 30mDelta
Deal found 11/14$367
This Delta deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:45 amGSP - STL
1 stop5h 00mDelta
Sun 12/149:30 amSTL - GSP
1 stop4h 08mDelta
Deal found 11/15$387
This American Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:12 amGSP - STL
1 stop7h 12mAmerican Airlines
Fri 1/25:00 amSTL - GSP
1 stop6h 19mAmerican Airlines
Deal found 11/14$423
This Southwest deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:40 amGSP - STL
1 stop9h 25mSouthwest
Fri 1/23:05 pmSTL - GSP
2 stops5h 50mSouthwest
Deal found 11/14$468
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:05 amGSP - STL
1 stop6h 18mUnited Airlines
Sun 12/146:30 amSTL - GSP
2 stops6h 47mUnited Airlines
Deal found 11/15$517

Cheap flight deals from Greenville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$331
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$406
Provider with most accurate pricing for Greenville-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Lambert-St Louis flights.
Search Deals
From Greenville to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.

Fly from

Greenville

Fly to

St. Louis

Route

Depart

Return

Price

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 1/15

6:00 am-11:41 am

1 stop6h 41m

Lambert-St Louis

Sun 1/18

1:35 pm-11:59 pm

1 stop9h 24m

$331

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Mon 12/8

3:23 pm-5:56 pm

1 stop3h 33m

Lambert-St Louis

Tue 12/9

7:05 am-2:38 pm

1 stop6h 33m

$342

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Mon 12/8

3:05 pm-9:00 pm

1 stop6h 55m

Lambert-St Louis

Tue 12/9

5:45 am-2:30 pm

1 stop7h 45m

$342

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Mon 12/8

9:05 am-3:40 pm

1 stop7h 35m

Lambert-St Louis

Tue 12/9

12:55 pm-11:59 pm

2 stops10h 04m

$347

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 12/7

7:25 am-1:53 pm

1 stop7h 28m

Lambert-St Louis

Thu 12/11

7:02 pm-11:40 pm

1 stop3h 38m

$354

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Sun 12/7

8:00 am-4:40 pm

2 stops9h 40m

Lambert-St Louis

Thu 12/11

5:45 am-2:30 pm

1 stop7h 45m

$359

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Fri 12/12

6:45 am-10:45 am

1 stop5h 00m

Lambert-St Louis

Sun 12/14

9:30 am-2:38 pm

1 stop4h 08m

$387

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Thu 1/15

10:00 am-5:43 pm

2 stops8h 43m

Lambert-St Louis

Sun 1/18

9:57 am-4:52 pm

1 stop5h 55m

$407

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Fri 12/26

11:12 am-5:24 pm

1 stop7h 12m

Lambert-St Louis

Fri 1/2

5:00 am-12:19 pm

1 stop6h 19m

$423

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Fri 12/26

7:40 am-4:05 pm

1 stop9h 25m

Lambert-St Louis

Fri 1/2

3:05 pm-9:55 pm

2 stops5h 50m

$468

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 13 results
1
2

Compare providers for flights from Greenville to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Greenville-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Greenville-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to St. Louis

What is the cheapest month to book a flight from Greenville to St. Louis?

Currently, June is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $108). Flying from Greenville to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to STL?

Find hourly flight availability from Greenville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 16, 2025.

When flying from Greenville to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 16% versus a flight in the evening.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated November 16, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Greenville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,244 reviews

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to St. Louis?

    There are many flights that can get you from Greenville to St. Louis in 3h 33m. Fly via American Airlines, Delta, or Southwest to get the fastest option. Airlines will cover a distance of 523 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Greenville to St. Louis round-trip?

    According to our current data, Delta ($236), American Airlines ($286), and Southwest ($288) offers the cheapest pricing from Greenville to St. Louis. Delta is priced at 38% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Greenville to St. Louis one-way?

    $184 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Southwest and United Airlines, with prices starting from $241 and $772, respectively.

  • Can I find deals for flights from Greenville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Greenville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to St. Louis.

  • Can I find deals for business class flights from Greenville to St. Louis?

    Yes. Cheapflights offers flight deals from Greenville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to St. Louis?

    Currently, June is the cheapest month in which you can book a flight from Greenville to St. Louis (average of $108). Flying from Greenville to St. Louis in March is currently the most expensive (average of $224). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Greenville to St. Louis

Discover the top 3 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$369FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$286Average$406FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$288Average$466FlexibilityNo cancel feeOn-time63%

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