$113+ Cheap flights from Greenville to St. Louis (GSP - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — STL
Mar 15 — Mar 221
1 adult, Economy
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Find cheap flights from Greenville to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to St. Louis
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Best
Last-minute
One-way
Cheapest flights from Greenville to St. LouisExplore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from Greenville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:46 pm
GSP
- STL
2 stops16h 48m
Multiple Airlines
Wed 3/254:51 pm
STL
- GSP
1 stop20h 16m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$282
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:28 am
GSP
- STL
1 stop13h 16m
American Airlines
Wed 4/812:25 pm
STL
- GSP
1 stop9h 38m
American Airlines
Deal found 2/11![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:40 am
GSP
- STL
1 stop4h 25m
Delta
Wed 3/256:59 pm
STL
- GSP
1 stop3h 55m
Delta
Deal found 2/11![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:35 pm
GSP
- STL
2 stops8h 25m
Southwest
Wed 3/186:00 pm
STL
- GSP
1 stop3h 40m
Southwest
Deal found 2/11![Southwest logo]()
$302
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:50 pm
GSP
- STL
2 stops7h 10m
Southwest
Wed 4/812:40 pm
STL
- GSP
2 stops8h 00m
Southwest
Deal found 2/10![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:01 am
GSP
- STL
1 stop6h 00m
American Airlines
Tue 3/108:00 am
STL
- GSP
1 stop10h 46m
American Airlines
Deal found 2/10![American Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:59 pm
GSP
- STL
1 stop4h 59m
Delta
Tue 4/76:00 am
STL
- GSP
1 stop4h 05m
Delta
Deal found 2/11![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:35 pm
GSP
- STL
2 stops9h 10m
Southwest
Tue 3/1012:20 pm
STL
- GSP
1 stop7h 10m
Southwest
Deal found 2/10![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:55 pm
GSP
- STL
1 stop8h 21m
American Airlines
Mon 3/166:33 pm
STL
- GSP
1 stop4h 09m
American Airlines
Deal found 2/9![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:30 am
GSP
- STL
1 stop10h 11m
American Airlines
Fri 4/243:42 pm
STL
- GSP
1 stop5h 37m
American Airlines
Deal found 2/10![American Airlines logo]()
$331
Best flights from Greenville to St. LouisDiscover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from Greenville to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:28 am
GSP
- STL
1 stop13h 16m
American Airlines
Wed 4/812:25 pm
STL
- GSP
1 stop9h 38m
American Airlines
Deal found 2/11![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:40 am
GSP
- STL
1 stop4h 25m
Delta
Wed 3/256:59 pm
STL
- GSP
1 stop3h 55m
Delta
Deal found 2/11![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:35 pm
GSP
- STL
2 stops8h 25m
Southwest
Wed 3/186:00 pm
STL
- GSP
1 stop3h 40m
Southwest
Deal found 2/11![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:32 pm
GSP
- STL
1 stop4h 35m
United Airlines
Wed 3/117:40 am
STL
- GSP
2 stops10h 48m
United Airlines
Deal found 2/10![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:50 pm
GSP
- STL
2 stops7h 10m
Southwest
Wed 4/811:35 am
STL
- GSP
1 stop3h 45m
Southwest
Deal found 2/10![Southwest logo]()
$302
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:22 am
GSP
- STL
1 stop8h 34m
American Airlines
Wed 3/112:29 pm
STL
- GSP
1 stop8h 13m
American Airlines
Deal found 2/10![American Airlines logo]()
$308
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:59 pm
GSP
- STL
1 stop4h 59m
Delta
Tue 4/76:00 am
STL
- GSP
1 stop4h 05m
Delta
Deal found 2/11![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:20 am
GSP
- STL
2 stops9h 10m
Southwest
Wed 3/256:00 pm
STL
- GSP
1 stop3h 40m
Southwest
Deal found 2/11![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:35 pm
GSP
- STL
2 stops9h 10m
Southwest
Tue 3/1012:20 pm
STL
- GSP
1 stop7h 10m
Southwest
Deal found 2/10![Southwest logo]()
$314
Last-minute flights from Greenville to St. LouisDiscover last-minute flight deals from Greenville to St. Louis. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to St. Louis. Data last updated February 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/212:55 pm
GSP
- STL
1 stop8h 21m
American Airlines
Mon 3/166:33 pm
STL
- GSP
1 stop4h 09m
American Airlines
Deal found 2/9![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:01 am
GSP
- STL
1 stop6h 00m
American Airlines
Tue 3/108:00 am
STL
- GSP
1 stop10h 46m
American Airlines
Deal found 2/10![American Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/712:35 pm
GSP
- STL
2 stops9h 10m
Southwest
Tue 3/1012:20 pm
STL
- GSP
1 stop7h 10m
Southwest
Deal found 2/10![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:35 pm
GSP
- STL
2 stops8h 25m
Southwest
Wed 3/186:00 pm
STL
- GSP
1 stop3h 40m
Southwest
Deal found 2/11![Southwest logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:46 pm
GSP
- STL
2 stops16h 48m
Multiple Airlines
Wed 3/254:51 pm
STL
- GSP
1 stop20h 16m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$282
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:40 am
GSP
- STL
1 stop4h 25m
Delta
Wed 3/256:59 pm
STL
- GSP
1 stop3h 55m
Delta
Deal found 2/11![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:25 pm
GSP
- STL
1 stop6h 40m
Southwest
Sun 3/295:50 am
STL
- GSP
1 stop6h 25m
Southwest
Deal found 2/10![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/307:59 pm
GSP
- STL
1 stop4h 59m
Delta
Tue 4/75:21 pm
STL
- GSP
1 stop3h 31m
Delta
Deal found 2/12![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:28 am
GSP
- STL
1 stop13h 16m
American Airlines
Wed 4/812:25 pm
STL
- GSP
1 stop9h 38m
American Airlines
Deal found 2/11![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:50 pm
GSP
- STL
2 stops7h 10m
Southwest
Wed 4/812:40 pm
STL
- GSP
2 stops8h 00m
Southwest
Deal found 2/10![Southwest logo]()
$307
One-way flights from Greenville to St. LouisSearch for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from Greenville to St. Louis. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:49 pm
GSP
- STL
2 stops37h 02m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$113
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:30 am
GSP
- STL
1 stop6h 28m
Delta
Deal found 2/11![Delta logo]()
$149
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:35 pm
GSP
- STL
2 stops8h 25m
Southwest
Deal found 2/11![Southwest logo]()
$154
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:30 am
GSP
- STL
1 stop5h 06m
United Airlines
Deal found 2/11![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/224:25 pm
GSP
- STL
2 stops8h 30m
Southwest
Deal found 2/11![Southwest logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/112:34 pm
GSP
- STL
3 stops25h 37m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$822
Find flight deals from Greenville to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $282 (Kiwi.com) |
One-way from | $113 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Greenville to St. Louis that are best for you.
Fly from
Greenville
Fly to
St. Louis
Route
Depart
Return
Price
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Tue 3/31
11:28 am-11:44 pm
1 stop13h 16m
Lambert-St Louis
Wed 4/8
12:25 pm-11:03 pm
1 stop9h 38m
$295
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 3/25
5:40 am-9:05 am
1 stop4h 25m
Lambert-St Louis
Wed 3/25
6:59 pm-11:54 pm
1 stop3h 55m
$297
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 3/11
12:35 pm-8:00 pm
2 stops8h 25m
Lambert-St Louis
Wed 3/18
6:00 pm-10:40 pm
1 stop3h 40m
$302
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Tue 3/31
1:50 pm-8:00 pm
2 stops7h 10m
Lambert-St Louis
Wed 4/8
11:35 am-4:20 pm
1 stop3h 45m
$302
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 3/9
7:22 am-2:56 pm
1 stop8h 34m
Lambert-St Louis
Wed 3/11
2:29 pm-11:42 pm
1 stop8h 13m
$308
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Wed 3/25
6:20 am-2:30 pm
2 stops9h 10m
Lambert-St Louis
Wed 3/25
6:00 pm-10:40 pm
1 stop3h 40m
$308
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 3/30
7:59 pm-11:58 pm
1 stop4h 59m
Lambert-St Louis
Tue 4/7
6:00 am-11:05 am
1 stop4h 05m
$309
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 3/9
5:32 pm-9:07 pm
1 stop4h 35m
Lambert-St Louis
Wed 3/11
7:40 am-7:28 pm
2 stops10h 48m
$314
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Sat 3/7
12:35 pm-8:45 pm
2 stops9h 10m
Lambert-St Louis
Tue 3/10
12:20 pm-8:30 pm
1 stop7h 10m
$314
GreenvilleSt. Louis
GSP - STL
GSPSTL
Greenville
Mon 3/2
6:49 pm-6:51 am
2 stops37h 02m
$113
Showing 1-10 of 15 results
Compare providers for flights from Greenville to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to St. Louis in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Greenville with our price prediction graph.
GSP-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to St. Louis
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated February 13, 2026.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Greenville to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Greenville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus
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Greenville and St. Louis flights
Browse other Greenville and St. Louis flight options. Last updated on February 13, 2026.
Other flights from Greenville
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Other flights to St. Louis
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Top 3 airlines flying from Greenville to St. Louis
Discover the top 3 airlines that operate flights from Greenville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$384 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$416 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$426 | FlexibilityNo cancel fee | On-time63% |