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St. Louis

$328+ Cheap flights from Gainesville to St. Louis (GNV - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
may. 2 — may. 91
sáb. 5/2
sáb. 5/9
1 adult, Economy
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Cheap flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 2, 2026.

This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/77:05 pm
GNV
-
STL
1 stop5h 54m
Delta
dom. 5/107:15 am
STL
-
GNV
1 stop4h 07m
Delta
Deal found 3/31$437
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/76:00 am
GNV
-
STL
1 stop5h 16m
American Airlines
dom. 5/108:54 am
STL
-
GNV
2 stops9h 39m
American Airlines
Deal found 3/31$442
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/16:24 am
GNV
-
STL
1 stop7h 19m
American Airlines
sáb. 4/44:13 pm
STL
-
GNV
1 stop5h 47m
American Airlines
Deal found 3/31$443
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/221:49 pm
GNV
-
STL
1 stop6h 11m
American Airlines
lun. 5/256:12 pm
STL
-
GNV
1 stop5h 21m
American Airlines
Deal found 3/30$459
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/25:18 pm
GNV
-
STL
1 stop7h 23m
American Airlines
lun. 10/53:03 pm
STL
-
GNV
2 stops8h 13m
American Airlines
Deal found 3/30$469
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/162:02 pm
GNV
-
STL
1 stop4h 42m
Delta
lun. 4/201:02 pm
STL
-
GNV
1 stop4h 15m
Delta
Deal found 4/1$477
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/166:30 am
GNV
-
STL
2 stops8h 33m
American Airlines
lun. 4/209:10 am
STL
-
GNV
1 stop7h 07m
American Airlines
Deal found 4/1$482
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/211:49 pm
GNV
-
STL
2 stops7h 41m
American Airlines
lun. 5/256:12 pm
STL
-
GNV
1 stop5h 21m
American Airlines
Deal found 4/1$486

Find flight deals from Gainesville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated abril 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$437
(Delta)

One-way from

$328
(Delta)

Popular in

March

Cheapest in

April

Average price

$139
Provider with most accurate pricing for Gainesville Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Lambert-St Louis flights.
Search Deals
From Gainesville Regional to Lambert-St Louis
Search Deals
One-way flight from Gainesville Regional to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 20% potential increase in price ($121 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2026.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

jue. 5/7

7:05 pm-11:59 pm

1 stop5h 54m

Lambert-St Louis

dom. 5/10

6:00 am-12:22 pm

1 stop5h 22m

$437

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

jue. 5/7

5:14 pm-10:59 pm

1 stop6h 45m

Lambert-St Louis

dom. 5/10

7:05 am-5:17 pm

2 stops9h 12m

$442
Quickest round-trip

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

jue. 5/21

7:32 pm-11:44 pm

1 stop5h 12m

Lambert-St Louis

lun. 5/25

6:12 pm-12:33 am

1 stop5h 21m

$459

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

vie. 5/22

1:49 pm-8:30 pm

2 stops7h 41m

Lambert-St Louis

lun. 5/25

5:18 pm-11:46 pm

1 stop5h 28m

$583
Cheapest one-way

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

vie. 9/18

10:20 am-3:57 pm

1 stop6h 37m

$328
Quickest one-way

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

vie. 9/18

5:54 pm-11:20 pm

2 stops6h 26m

$333

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

jue. 4/30

5:14 pm-10:59 pm

1 stop6h 45m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Gainesville-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $40). Flying from Gainesville to St. Louis in June is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Gainesville to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated abril 2, 2026.
See what other customers who have flown with Delta from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,370 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,370 reviews
Delta
7.9
Good
8,370 reviews

Overall

7.9

Entertainment

7.8

Comfort

7.9

Crew

8.5

Food

7.2

Boarding

8.1

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to St. Louis?

    For as low as $437, Delta can have you in St. Louis from Gainesville in 5h 54m. The distance from Gainesville to St. Louis is about 777 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Gainesville to St. Louis round-trip?

    Currently priced at $208, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Delta is 57% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.

  • Can I find deals for business class flights from Gainesville to St. Louis?

    Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $40). Flying from Gainesville to St. Louis in June is currently the most expensive (average of $145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Gainesville to St. Louis

Discover the top airline that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$376FlexibilityNo cancel feeOn-timeN/A

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