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St. Louis

$309+ Cheap flights from Gainesville to St. Louis (GNV - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Gainesville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$357
(Delta)

One-way from

$309
(Delta)

Popular in

October

Cheapest in

August

Average price

$661
From Gainesville Regional to Lambert-St Louis
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One-way flight from Gainesville Regional to Lambert-St Louis
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Highest demand for flights based on searches. 29% potential increase in price ($188 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:44 pmGNV - STL
1 stop5h 14mAmerican Airlines
Mon 10/207:23 amSTL - GNV
1 stop4h 53mAmerican Airlines
Deal found 9/15$377
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2010:10 amGNV - STL
1 stop5h 38mDelta
Tue 9/236:01 amSTL - GNV
1 stop5h 30mDelta
Deal found 9/14$395
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/107:07 pmGNV - STL
1 stop5h 34mDelta
Mon 10/136:00 amSTL - GNV
1 stop5h 47mDelta
Deal found 9/15$397
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:10 amGNV - STL
1 stop6h 55mDelta
Sun 10/57:10 amSTL - GNV
1 stop4h 21mDelta
Deal found 9/15$416
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:00 amGNV - STL
2 stops10h 37mAmerican Airlines
Sun 10/55:27 amSTL - GNV
1 stop7h 08mAmerican Airlines
Deal found 9/15$421
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:13 amGNV - STL
2 stops7h 38mAmerican Airlines
Tue 10/78:42 amSTL - GNV
2 stops8h 47mAmerican Airlines
Deal found 9/17$426
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/29:15 amGNV - STL
1 stop7h 31mAmerican Airlines
Sun 10/57:22 amSTL - GNV
1 stop5h 13mAmerican Airlines
Deal found 9/15$437
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amGNV - STL
1 stop3h 44mDelta
Mon 9/2211:04 amSTL - GNV
1 stop6h 17mDelta
Deal found 9/15$450
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amGNV - STL
1 stop4h 16mAmerican Airlines
Mon 9/291:03 pmSTL - GNV
2 stops9h 10mAmerican Airlines
Deal found 9/17$455

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Fly from

Gainesville

Fly to

St. Louis

Route

Depart

Return

Price

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Thu 10/16

7:44 pm-11:58 pm

1 stop5h 14m

Lambert-St Louis

Mon 10/20

7:23 am-1:16 pm

1 stop4h 53m

$377

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Sat 9/20

10:10 am-2:48 pm

1 stop5h 38m

Lambert-St Louis

Tue 9/23

6:01 am-12:31 pm

1 stop5h 30m

$395

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 10/10

7:07 pm-11:41 pm

1 stop5h 34m

Lambert-St Louis

Mon 10/13

6:00 am-12:47 pm

1 stop5h 47m

$397

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 10/1

10:10 am-4:05 pm

1 stop6h 55m

Lambert-St Louis

Sun 10/5

7:10 am-12:31 pm

1 stop4h 21m

$416

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 10/1

6:00 am-3:37 pm

2 stops10h 37m

Lambert-St Louis

Sun 10/5

5:27 am-1:35 pm

1 stop7h 08m

$421

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Thu 10/2

6:13 am-12:51 pm

2 stops7h 38m

Lambert-St Louis

Tue 10/7

8:42 am-6:29 pm

2 stops8h 47m

$426

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Thu 10/2

9:15 am-3:46 pm

1 stop7h 31m

Lambert-St Louis

Sun 10/5

7:22 am-1:35 pm

1 stop5h 13m

$437

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Sat 9/20

6:00 am-8:44 am

1 stop3h 44m

Lambert-St Louis

Mon 9/22

11:04 am-6:21 pm

1 stop6h 17m

$450

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Tue 9/23

10:10 am-2:35 pm

1 stop5h 25m

$309

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Mon 9/22

7:06 pm-11:24 pm

1 stop5h 18m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 12 results
1
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Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to STL?

Find hourly flight availability from Gainesville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from Gainesville to St. Louis by exploring options for tickets in the morning.

How much does it cost to fly round-trip from Gainesville to St. Louis?

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to St. Louis?

    For as low as $377, American Airlines can have you in St. Louis from Gainesville in 5h 14m. The distance from Gainesville to St. Louis is about 777 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to St. Louis round-trip?

    Currently priced at $208, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $298. Delta is 53% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.

  • Can I find deals for business class flights from Gainesville to St. Louis?

    Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

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Top 2 airlines flying from Gainesville to St. Louis

Discover the top 2 airlines that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$386FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$298Average$475FlexibilityNo cancel feeOn-time71%

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