HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$309+ Cheap flights from Gainesville to St. Louis (GNV - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$358
(Delta)

One-way from

$309
(Delta)

Popular in

October

Cheapest in

August

Average price

$763
Provider with most accurate pricing for Gainesville Regional-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Lambert-St Louis flights.
Search Deals
From Gainesville Regional to Lambert-St Louis
Search Deals
One-way flight from Gainesville Regional to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 25% potential increase in price ($152 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:04 pmGNV - STL
1 stop3h 54mDelta
Tue 12/27:05 amSTL - GNV
1 stop4h 53mDelta
Deal found 10/30$358
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:00 amGNV - STL
1 stop5h 37mAmerican Airlines
Tue 12/22:11 pmSTL - GNV
2 stops8h 48mAmerican Airlines
Deal found 10/30$372
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amGNV - STL
1 stop5h 43mDelta
Sat 11/156:00 amSTL - GNV
1 stop5h 52mDelta
Deal found 10/29$435
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:02 pmGNV - STL
2 stops8h 58mAmerican Airlines
Sat 11/157:00 amSTL - GNV
1 stop5h 23mAmerican Airlines
Deal found 10/29$440
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/71:32 pmGNV - STL
1 stop3h 38mDelta
Sun 11/96:00 amSTL - GNV
1 stop5h 52mDelta
Deal found 10/30$545
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amGNV - STL
2 stops8h 40mAmerican Airlines
Sun 11/97:00 amSTL - GNV
1 stop5h 23mAmerican Airlines
Deal found 10/30$550
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/258:00 pmGNV - STL
1 stop5h 05mAmerican Airlines
Sun 11/305:00 amSTL - GNV
1 stop4h 50mAmerican Airlines
Deal found 10/30$717
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/26:35 pmGNV - STL
1 stop4h 03mDelta
Tue 11/47:05 amSTL - GNV
1 stop4h 42mDelta
Deal found 10/29$792
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:36 amGNV - STL
2 stops8h 04mAmerican Airlines
Tue 11/49:36 amSTL - GNV
1 stop5h 08mAmerican Airlines
Deal found 10/29$797

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Fly from

Gainesville

Fly to

St. Louis

Route

Depart

Return

Price

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Tue 11/25

7:04 pm-9:58 pm

1 stop3h 54m

Lambert-St Louis

Tue 12/2

7:05 am-12:58 pm

1 stop4h 53m

$358

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Tue 11/25

6:00 am-10:37 am

1 stop5h 37m

Lambert-St Louis

Tue 12/2

2:11 pm-11:59 pm

2 stops8h 48m

$372

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 3/27

7:05 pm-11:40 pm

1 stop5h 35m

Lambert-St Louis

Tue 3/31

10:00 am-4:06 pm

1 stop5h 06m

$372

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 11/12

6:00 am-10:43 am

1 stop5h 43m

Lambert-St Louis

Sat 11/15

6:00 am-12:52 pm

1 stop5h 52m

$435

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 11/12

1:02 pm-9:00 pm

2 stops8h 58m

Lambert-St Louis

Sat 11/15

7:00 am-1:23 pm

1 stop5h 23m

$440

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 3/27

6:27 am-2:48 pm

2 stops9h 21m

Lambert-St Louis

Tue 3/31

12:58 pm-12:10 am

2 stops10h 12m

$521

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Tue 11/25

8:00 pm-12:05 am

1 stop5h 05m

Lambert-St Louis

Sun 11/30

5:00 am-10:50 am

1 stop4h 50m

$717

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 12/10

10:10 am-12:57 pm

1 stop3h 47m

$309

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 12/26

6:30 am-1:14 pm

1 stop7h 44m

$309

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Wed 12/10

6:30 am-1:41 pm

2 stops8h 11m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 14 results
1
2

Compare providers for flights from Gainesville to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to St. Louis in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-St. Louis flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Gainesville-St. Louis flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Gainesville-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-St. Louis flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $60). Flying from Gainesville to St. Louis in June is currently the most expensive (average of $143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to STL?

Find hourly flight availability from Gainesville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 21% on flights from Gainesville to St. Louis by exploring options for tickets in the morning.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 30, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Boarding

8.2

Crew

8.5

Overall

7.9

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to St. Louis?

    For as low as $358, Delta can have you in St. Louis from Gainesville in 3h 54m. The distance from Gainesville to St. Louis is about 777 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to St. Louis round-trip?

    Currently priced at $208, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $298. Delta is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.

  • Can I find deals for business class flights from Gainesville to St. Louis?

    Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $60). Flying from Gainesville to St. Louis in June is currently the most expensive (average of $143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to St. Louis flights
Orlando to Kansas City flights
Tampa to Kansas City flights
Fort Lauderdale to St. Louis flights
Miami to Kansas City flights
Fort Lauderdale to Kansas City flights
Tampa to St. Louis flights
Miami to St. Louis flights
Jacksonville to St. Louis flights
Jacksonville to Kansas City flights
West Palm Beach to Kansas City flights
Pensacola to Kansas City flights
Pensacola to Springfield flights
Fort Myers to Kansas City flights
Miami to Springfield flights
Jacksonville to Springfield flights
Fort Myers to St. Louis flights
Sarasota to St. Louis flights
Sarasota to Kansas City flights
Sarasota to Springfield flights
Pensacola to St. Louis flights
West Palm Beach to St. Louis flights
Orlando to Springfield flights
Fort Myers to Springfield flights
Fort Lauderdale to Springfield flights
West Palm Beach to Springfield flights
Tampa to Springfield flights
Fort Lauderdale to Columbia flights
Panama City to St. Louis flights
Orlando to Joplin flights
Pensacola to Columbia flights
West Palm Beach to Columbia flights
Orlando to Columbia flights
Tallahassee to St. Louis flights
Gainesville to Kansas City flights
Daytona Beach to St. Louis flights
Melbourne to Kansas City flights
Tallahassee to Kansas City flights
Sarasota to Joplin flights
Panama City to Springfield flights
Tallahassee to Springfield flights
Panama City to Kansas City flights
Melbourne to St. Louis flights
Daytona Beach to Kansas City flights
Tampa to Columbia flights
Fort Myers to Joplin flights
Valdosta to Kansas City flights
Valparaiso to Kansas City flights
Melbourne to Springfield flights

Top 2 airlines flying from Gainesville to St. Louis

Discover the top 2 airlines that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$386FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$298Average$455FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.