HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
St. Louis

$337+ Cheap flights from Gainesville to St. Louis (GNV - STL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — STL
Aug 22 — Aug 291
Fri 8/22
Fri 8/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to St. Louis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 17, 2025.

Round-trip from

$337
(Delta)

Popular in

October

Cheapest in

August

Average price

$278
From Gainesville Regional to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($87 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Gainesville to St. Louis

Cheapest flights from Gainesville to St. Louis
Explore the most affordable flight options available from Gainesville to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This Delta deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/202:10 pmGNV - STL
1 stop5h 55mDelta
Tue 9/239:19 amSTL - GNV
1 stop4h 57mDelta
Deal found 8/16$337
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:13 amGNV - STL
2 stops10h 57mAmerican Airlines
Tue 9/239:57 amSTL - GNV
1 stop5h 11mAmerican Airlines
Deal found 8/16$412
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/224:20 pmGNV - STL
1 stop7h 54mAmerican Airlines
Sat 8/235:22 amSTL - GNV
1 stop7h 07mAmerican Airlines
Deal found 8/16$450
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/254:20 pmGNV - STL
1 stop7h 54mAmerican Airlines
Mon 9/17:32 amSTL - GNV
1 stop4h 55mAmerican Airlines
Deal found 8/15$461
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/187:01 pmGNV - STL
1 stop5h 13mDelta
Wed 8/206:00 amSTL - GNV
1 stop5h 26mDelta
Deal found 8/15$485
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:00 amGNV - STL
1 stop4h 15mDelta
Fri 9/55:11 pmSTL - GNV
1 stop4h 35mDelta
Deal found 8/17$509
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2910:17 amGNV - STL
1 stop6h 49mDelta
Mon 9/110:20 amSTL - GNV
1 stop6h 30mDelta
Deal found 8/15$523

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Gainesville to St. Louis that are best for you.

Fly from

Gainesville

Fly to

St. Louis

Route

Depart

Return

Price

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Sat 9/20

2:10 pm-7:05 pm

1 stop5h 55m

Lambert-St Louis

Tue 9/23

9:19 am-3:16 pm

1 stop4h 57m

$337

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Sat 9/20

4:43 pm-11:07 pm

1 stop7h 24m

Lambert-St Louis

Tue 9/23

7:16 am-4:08 pm

2 stops7h 52m

$412

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Mon 9/1

6:00 am-9:15 am

1 stop4h 15m

Lambert-St Louis

Fri 9/5

5:11 pm-10:46 pm

1 stop4h 35m

$509

GainesvilleSt. Louis

GNV - STL

GNVSTL

Gainesville Regional

Fri 8/29

10:17 am-4:06 pm

1 stop6h 49m

Lambert-St Louis

Mon 9/1

10:20 am-5:50 pm

1 stop6h 30m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Gainesville to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to St. Louis

What is the cheapest month to book a flight from Gainesville to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to STL?

Find hourly flight availability from Gainesville to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from Gainesville to St. Louis by exploring options for tickets in the morning.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated August 17, 2025.
See what other customers who have flown with Delta and American Airlines from Gainesville to St. Louis have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,986 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,986 reviews
Delta
8.0
Very good
7,986 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,986 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Gainesville to St. Louis round-trip?

    Currently priced at $208, Delta will fly you from Gainesville to St. Louis and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $318. Delta is 49% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Gainesville to St. Louis that include hotel bookings?

    Yes. In addition to deals on Gainesville to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to St. Louis.

  • Can I find deals for business class flights from Gainesville to St. Louis?

    Yes. Cheapflights offers flight deals from Gainesville to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Gainesville to St. Louis (average of $311). Flying from Gainesville to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Tampa to Kansas City flights
Orlando to St. Louis flights
Orlando to Kansas City flights
Jacksonville to St. Louis flights
Miami to St. Louis flights
Fort Myers to St. Louis flights
Miami to Kansas City flights
Tampa to St. Louis flights
Fort Myers to Kansas City flights
Fort Lauderdale to St. Louis flights
Fort Lauderdale to Kansas City flights
West Palm Beach to Springfield flights
Sarasota to Kansas City flights
Pensacola to St. Louis flights
Panama City to Kansas City flights
Orlando to Springfield flights
Sarasota to St. Louis flights
West Palm Beach to St. Louis flights
Jacksonville to Springfield flights
Pensacola to Kansas City flights
Valparaiso to Kansas City flights
Jacksonville to Kansas City flights
Tampa to Springfield flights
West Palm Beach to Kansas City flights
Valparaiso to St. Louis flights
Fort Myers to Springfield flights
Panama City to St. Louis flights
Sarasota to Springfield flights
Pensacola to Springfield flights
Daytona Beach to Kansas City flights
Orlando to Joplin flights
Fort Myers to Joplin flights
Miami to Springfield flights
Panama City to Springfield flights
Fort Lauderdale to Springfield flights
Orlando to Columbia flights
Melbourne to Springfield flights
Sarasota to Joplin flights
Fort Lauderdale to Columbia flights
Daytona Beach to St. Louis flights
Daytona Beach to Springfield flights
Jacksonville to Joplin flights
Melbourne to St. Louis flights
Valdosta to Kansas City flights
Gainesville to Springfield flights
Tampa to Columbia flights
Tallahassee to St. Louis flights
Melbourne to Kansas City flights
Tallahassee to Springfield flights

Top 2 airlines flying from Gainesville to St. Louis

Discover the top 2 airlines that operate flights from Gainesville to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$388FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$318Average$455FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.