$304+ Cheap flights from Sioux Falls (FSD) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CLT
Jul 25 — Aug 11
Round-trip
1 adult, Economy
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Last-minute
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Cheapest flights from Sioux Falls to SpartanburgExplore the most affordable flight options available from Sioux Falls to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
Explore the most affordable flight options available from Sioux Falls to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:34 pm
FSD
- CLT
1 stop6h 25m
American Airlines
Sat 7/254:52 pm
CLT
- FSD
1 stop6h 06m
American Airlines
Deal found 6/20![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:23 am
FSD
- CLT
1 stop4h 34m
Delta
Wed 7/296:58 pm
CLT
- FSD
1 stop5h 08m
Delta
Deal found 6/24![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:00 pm
FSD
- CLT
1 stop6h 59m
American Airlines
Sun 7/129:42 am
CLT
- FSD
1 stop7h 32m
American Airlines
Deal found 6/25![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:00 am
FSD
- CLT
1 stop4h 24m
Delta
Sat 7/252:22 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/22![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:50 am
FSD
- CLT
1 stop5h 30m
United Airlines
Sun 10/46:45 am
CLT
- FSD
1 stop4h 44m
United Airlines
Deal found 6/24![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:24 am
FSD
- CLT
1 stop5h 08m
Delta
Wed 7/296:20 am
CLT
- FSD
1 stop7h 29m
Delta
Deal found 6/24![Delta logo]()
$399
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:20 am
FSD
- CLT
1 stop5h 01m
Delta
Sun 7/126:20 am
CLT
- FSD
1 stop4h 55m
Delta
Deal found 6/21![Delta logo]()
$404
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:47 am
FSD
- CLT
1 stop5h 09m
United Airlines
Tue 9/112:50 pm
CLT
- FSD
1 stop6h 08m
United Airlines
Deal found 6/24![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:57 pm
FSD
- CLT
1 stop8h 33m
American Airlines
Mon 9/78:31 pm
CLT
- FSD
1 stop4h 59m
American Airlines
Deal found 6/23![American Airlines logo]()
$439
Best flights from Sioux Falls to SpartanburgDiscover carefully curated flight deals from Sioux Falls to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
Discover carefully curated flight deals from Sioux Falls to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am
FSD
- CLT
1 stop7h 00m
Delta
Mon 9/287:16 pm
CLT
- FSD
1 stop4h 35m
Delta
Deal found 6/21![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:47 am
FSD
- CLT
1 stop5h 09m
United Airlines
Tue 9/112:50 pm
CLT
- FSD
1 stop6h 08m
United Airlines
Deal found 6/24![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:05 am
FSD
- CLT
1 stop6h 16m
Delta
Mon 9/77:18 pm
CLT
- FSD
1 stop4h 33m
Delta
Deal found 6/23![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:20 am
FSD
- CLT
1 stop7h 11m
Delta
Sun 8/166:24 am
CLT
- FSD
1 stop7h 14m
Delta
Deal found 6/20![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:00 am
FSD
- CLT
1 stop4h 24m
Delta
Sat 7/252:22 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/22![Delta logo]()
$379
Last-minute flights from Sioux Falls to SpartanburgDiscover last-minute flight deals from Sioux Falls to Spartanburg. Data last updated June 25, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Spartanburg. Data last updated June 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/234:40 pm
FSD
- CLT
1 stop6h 18m
American Airlines
Sun 6/288:10 pm
CLT
- FSD
1 stop5h 10m
American Airlines
Deal found 6/22![American Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/257:40 am
FSD
- CLT
2 stops10h 22m
United Airlines
Sat 6/276:40 pm
CLT
- FSD
1 stop5h 51m
United Airlines
Deal found 6/22![United Airlines logo]()
$512
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:35 pm
FSD
- CLT
1 stop6h 18m
American Airlines
Sun 6/288:10 pm
CLT
- FSD
1 stop5h 10m
American Airlines
Deal found 6/24![American Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:24 am
FSD
- CLT
1 stop5h 08m
Delta
Wed 7/296:20 am
CLT
- FSD
1 stop7h 29m
Delta
Deal found 6/24![Delta logo]()
$399
This CheapOair deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:14 pm
FSD
- CLT
1 stop24h 11m
Frontier
Sun 6/287:14 pm
CLT
- FSD
1 stop25h 05m
Frontier
Deal found 6/24![Frontier logo]()
$457
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/61:18 pm
FSD
- CLT
1 stop8h 50m
United Airlines
Fri 7/176:40 pm
CLT
- FSD
1 stop5h 51m
United Airlines
Deal found 6/25![United Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:00 pm
FSD
- CLT
1 stop6h 59m
American Airlines
Sun 7/129:42 am
CLT
- FSD
1 stop7h 32m
American Airlines
Deal found 6/25![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:20 am
FSD
- CLT
1 stop5h 01m
Delta
Sun 7/126:20 am
CLT
- FSD
1 stop4h 55m
Delta
Deal found 6/21![Delta logo]()
$404
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:00 am
FSD
- CLT
1 stop4h 24m
Delta
Sat 7/252:22 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/22![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:34 pm
FSD
- CLT
1 stop6h 25m
American Airlines
Sat 7/256:26 pm
CLT
- FSD
1 stop6h 52m
American Airlines
Deal found 6/25![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:34 pm
FSD
- CLT
1 stop6h 25m
American Airlines
Sat 7/254:52 pm
CLT
- FSD
1 stop6h 06m
American Airlines
Deal found 6/20![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:23 am
FSD
- CLT
1 stop4h 34m
Delta
Wed 7/296:58 pm
CLT
- FSD
1 stop5h 08m
Delta
Deal found 6/24![Delta logo]()
$339
One-way flights from Sioux Falls to SpartanburgSearch for one-way flight options from Sioux Falls to Spartanburg. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
Search for one-way flight options from Sioux Falls to Spartanburg. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
FSD
- CLT
1 stop6h 40m
Delta
Deal found 6/25![Delta logo]()
$304
Find flight deals from Sioux Falls to Spartanburg
Keep the following information in mind while searching for Sioux Falls to Spartanburg flight deals. Data was last updated June 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (American Airlines) |
One-way from | $304 (Delta) |
Popular in | December |
Cheapest in | November |
Average price | $368 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Sioux Falls to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 9/26
5:30 am-1:30 pm
1 stop7h 00m
Charlotte Douglas
Mon 9/28
7:16 pm-10:51 pm
1 stop4h 35m
$319
Quickest round-trip
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Thu 9/3
11:05 am-6:21 pm
1 stop6h 16m
Charlotte Douglas
Mon 9/7
7:18 pm-10:51 pm
1 stop4h 33m
$339
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 8/1
5:20 am-1:31 pm
1 stop7h 11m
Charlotte Douglas
Sun 8/16
6:24 am-12:38 pm
1 stop7h 14m
$339
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sun 7/19
5:00 am-10:24 am
1 stop4h 24m
Charlotte Douglas
Sat 7/25
2:22 pm-7:56 pm
1 stop6h 34m
$379
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 8/29
7:47 am-1:56 pm
1 stop5h 09m
Charlotte Douglas
Tue 9/1
12:50 pm-5:58 pm
1 stop6h 08m
$409
Cheapest one-way
Quickest one-way
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 8/22
5:30 am-1:10 pm
1 stop6h 40m
$304
Sorted by cheapest first
Best time to book a flight from Sioux Falls to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Sioux Falls with our price prediction graph.
FSD-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Spartanburg
FSD-SB1
FSD-CLT
How much does it cost to fly round-trip from Sioux Falls to Spartanburg?
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated June 25, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Overall
7.8
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
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Sioux Falls and Spartanburg flights
Browse other Sioux Falls and Spartanburg flight options. Last updated on June 25, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on June 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Spartanburg flights
Consider these flights traveling from Sioux Falls to Spartanburg.
Top 3 airlines flying from Sioux Falls to Spartanburg
Discover the top 3 airlines that operate flights from Sioux Falls to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$160 | Average$452 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$250 | Average$419 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$250 | Average$319 | FlexibilityNo cancel fee | On-timeN/A |