$131+ Cheap flights from Sioux Falls (FSD) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/31. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — CLT
Aug 3 — Aug 101
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Sioux Falls to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sioux Falls to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Sioux Falls to SpartanburgExplore the most affordable flight options available from Sioux Falls to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
Explore the most affordable flight options available from Sioux Falls to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:40 am
FSD
- CLT
1 stop4h 33m
Delta
Sun 9/136:20 am
CLT
- FSD
1 stop6h 59m
Delta
Deal found 7/3![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:47 am
FSD
- CLT
1 stop5h 18m
United Airlines
Sat 9/123:00 pm
CLT
- FSD
2 stops9h 12m
United Airlines
Deal found 6/30![United Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:56 am
FSD
- CLT
1 stop6h 06m
Delta
Thu 8/67:18 pm
CLT
- FSD
1 stop4h 33m
Delta
Deal found 6/30![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:01 pm
FSD
- CLT
1 stop5h 58m
American Airlines
Wed 7/226:26 pm
CLT
- FSD
1 stop6h 52m
American Airlines
Deal found 6/30![American Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
FSD
- CLT
1 stop8h 16m
United Airlines
Tue 8/2510:25 am
CLT
- FSD
2 stops8h 33m
United Airlines
Deal found 7/1![United Airlines logo]()
$361
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:23 am
FSD
- CLT
1 stop4h 34m
Delta
Sat 7/185:18 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/29![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Mon 8/243:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 6/29![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/78:22 am
FSD
- CLT
1 stop4h 35m
Delta
Sat 9/1211:31 am
CLT
- FSD
1 stop5h 15m
Delta
Deal found 7/2![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
FSD
- CLT
1 stop4h 59m
Delta
Sat 7/255:18 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/29![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:35 am
FSD
- CLT
2 stops10h 27m
United Airlines
Sat 8/86:40 pm
CLT
- FSD
1 stop5h 51m
United Airlines
Deal found 7/1![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Mon 8/313:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 6/30![United Airlines logo]()
$398
Best flights from Sioux Falls to SpartanburgDiscover carefully curated flight deals from Sioux Falls to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
Discover carefully curated flight deals from Sioux Falls to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:30 am
FSD
- CLT
1 stop7h 00m
Delta
Mon 9/287:16 pm
CLT
- FSD
1 stop4h 35m
Delta
Deal found 7/1![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Mon 8/243:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 6/29![United Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/64:28 pm
FSD
- CLT
1 stop6h 09m
Delta
Tue 9/152:25 pm
CLT
- FSD
1 stop6h 24m
Delta
Deal found 7/2![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:40 am
FSD
- CLT
1 stop4h 33m
Delta
Sun 9/136:20 am
CLT
- FSD
1 stop6h 59m
Delta
Deal found 7/3![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:33 pm
FSD
- CLT
1 stop8h 53m
United Airlines
Sat 9/58:05 am
CLT
- FSD
1 stop7h 26m
United Airlines
Deal found 6/29![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:33 pm
FSD
- CLT
1 stop6h 43m
United Airlines
Sat 8/223:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 7/1![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:58 am
FSD
- CLT
1 stop7h 01m
Delta
Mon 11/166:50 pm
CLT
- FSD
1 stop5h 01m
Delta
Deal found 7/4![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:47 am
FSD
- CLT
2 stops10h 09m
United Airlines
Sun 9/68:48 am
CLT
- FSD
1 stop8h 35m
United Airlines
Deal found 7/2![United Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:00 am
FSD
- CLT
1 stop4h 24m
Delta
Sat 7/252:22 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 7/3![Delta logo]()
$399
Last-minute flights from Sioux Falls to SpartanburgDiscover last-minute flight deals from Sioux Falls to Spartanburg. Data last updated July 4, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Spartanburg. Data last updated July 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:23 am
FSD
- CLT
1 stop4h 34m
Delta
Sat 7/185:18 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/29![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:01 pm
FSD
- CLT
1 stop5h 58m
American Airlines
Wed 7/226:26 pm
CLT
- FSD
1 stop6h 52m
American Airlines
Deal found 6/30![American Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:45 pm
FSD
- CLT
1 stop4h 59m
Delta
Sat 7/255:18 pm
CLT
- FSD
1 stop6h 34m
Delta
Deal found 6/29![Delta logo]()
$389
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2810:56 am
FSD
- CLT
1 stop6h 06m
Delta
Wed 8/56:24 am
CLT
- FSD
1 stop4h 56m
Delta
Deal found 7/2![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:56 am
FSD
- CLT
1 stop6h 06m
Delta
Thu 8/67:18 pm
CLT
- FSD
1 stop4h 33m
Delta
Deal found 6/30![Delta logo]()
$339
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/315:34 pm
FSD
- CLT
1 stop6h 25m
American Airlines
Sat 8/157:42 am
CLT
- FSD
1 stop4h 54m
American Airlines
Deal found 6/30![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:35 am
FSD
- CLT
2 stops10h 27m
United Airlines
Sat 8/86:40 pm
CLT
- FSD
1 stop5h 51m
United Airlines
Deal found 7/1![United Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Sat 8/224:23 pm
CLT
- FSD
1 stop8h 21m
United Airlines
Deal found 7/1![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
FSD
- CLT
1 stop8h 16m
United Airlines
Tue 8/2510:25 am
CLT
- FSD
2 stops8h 33m
United Airlines
Deal found 7/1![United Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Mon 8/243:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 6/29![United Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:06 pm
FSD
- CLT
1 stop5h 35m
United Airlines
Mon 8/313:00 pm
CLT
- FSD
2 stops9h 22m
United Airlines
Deal found 6/30![United Airlines logo]()
$398
One-way flights from Sioux Falls to SpartanburgSearch for one-way flight options from Sioux Falls to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
Search for one-way flight options from Sioux Falls to Spartanburg. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
This CheapOair deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:08 pm
FSD
- CLT
1 stop24h 11m
Frontier
Deal found 6/30![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:08 pm
FSD
- CLT
2 stops20h 04m
Frontier
Deal found 6/30![Frontier logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:40 pm
FSD
- CLT
2 stops23h 39m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/293:36 pm
FSD
- CLT
3 stops18h 53m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/291:18 pm
FSD
- CLT
1 stop8h 50m
United Airlines
Deal found 6/30![United Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:47 am
FSD
- CLT
2 stops10h 09m
United Airlines
Deal found 6/30![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:36 pm
FSD
- CLT
3 stops25h 31m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:26 pm
FSD
- CLT
1 stop6h 18m
Delta
Deal found 6/30![Delta logo]()
$479
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:35 am
FSD
- CLT
2 stops11h 47m
United Airlines
Deal found 6/30![United Airlines logo]()
$484
Find flight deals from Sioux Falls to Spartanburg
Keep the following information in mind while searching for Sioux Falls to Spartanburg flight deals. Data was last updated July 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Delta) |
One-way from | $131 (CheapOair) |
Popular in | December |
Cheapest in | November |
Average price | $318 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Sioux Falls to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 9/26
5:30 am-1:30 pm
1 stop7h 00m
Charlotte Douglas
Mon 9/28
7:16 pm-10:51 pm
1 stop4h 35m
$319
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sun 9/6
4:28 pm-11:37 pm
1 stop6h 09m
Charlotte Douglas
Tue 9/15
2:25 pm-7:49 pm
1 stop6h 24m
$319
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Wed 9/9
10:40 am-4:13 pm
1 stop4h 33m
Charlotte Douglas
Sun 9/13
6:20 am-12:19 pm
1 stop6h 59m
$319
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Fri 8/21
3:06 pm-9:41 pm
1 stop5h 35m
Charlotte Douglas
Mon 8/24
3:00 pm-11:22 pm
2 stops9h 22m
$370
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Tue 11/10
10:58 am-6:59 pm
1 stop7h 01m
Charlotte Douglas
Mon 11/16
6:50 pm-10:51 pm
1 stop5h 01m
$379
Quickest round-trip
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sun 7/19
5:00 am-10:24 am
1 stop4h 24m
Charlotte Douglas
Sat 7/25
2:22 pm-7:56 pm
1 stop6h 34m
$399
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Tue 9/1
1:33 pm-11:26 pm
1 stop8h 53m
Charlotte Douglas
Sat 9/5
8:05 am-2:31 pm
1 stop7h 26m
$409
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Sat 8/15
1:33 pm-9:16 pm
1 stop6h 43m
Charlotte Douglas
Sat 8/22
3:00 pm-11:22 pm
2 stops9h 22m
$414
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Wed 9/2
7:47 am-6:56 pm
2 stops10h 09m
Charlotte Douglas
Sun 9/6
8:48 am-4:23 pm
1 stop8h 35m
$414
Cheapest one-way
Quickest one-way
Sioux FallsCharlotte
FSD - CLT
FSDCLT
Sioux Falls Joe Foss Field
Tue 9/22
11:00 am-6:15 pm
1 stop6h 15m
$304
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Sioux Falls with our price prediction graph.
FSD-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Spartanburg
FSD-SB1
FSD-CLT
How much does it cost to fly round-trip from Sioux Falls to Spartanburg?
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated July 4, 2026.
Read reviews from past customers who have flown Delta,United Airlines, andAmerican Airlines from Sioux Falls to Spartanburg. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Sioux Falls
Popular flights
Top destinations
Alternative routes for Sioux Falls to Spartanburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Sioux Falls to Spartanburg by cabin class
Find flights from Sioux Falls to Spartanburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Sioux Falls and Spartanburg flights
Browse other Sioux Falls and Spartanburg flight options. Last updated on July 4, 2026.
Other flights from Sioux Falls
Browse through other flights departing from Sioux Falls. Flights are based on user searches made on Cheapflights and were last updated on July 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Sioux Falls to Spartanburg flights
Consider these flights traveling from Sioux Falls to Spartanburg.
Top 3 airlines flying from Sioux Falls to Spartanburg
Discover the top 3 airlines that operate flights from Sioux Falls to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$160 | Average$452 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$250 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$250 | Average$319 | FlexibilityNo cancel fee | On-timeN/A |