$80+ Cheap flights from Fort Myers (RSW) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — CLT
Mar 22 — Mar 291
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Fort Myers to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Spartanburg are usually found in September or October, booked 27 days in advance, depart on a Wednesday or Friday and return on a Sunday
Cheap flight deals from Fort Myers to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Fort Myers to SpartanburgExplore the most affordable flight options available from Fort Myers to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.
Explore the most affordable flight options available from Fort Myers to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.
This Travelocity deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:40 am
RSW
- CLT
1 stop11h 12m
Frontier
Sun 4/1910:39 pm
CLT
- RSW
1 stop12h 06m
Frontier
Deal found 2/18![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 am
RSW
- CLT
1 stop11h 12m
Frontier
Sun 5/107:49 pm
CLT
- RSW
1 stop20h 40m
Frontier
Deal found 2/19![Frontier logo]()
$171
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:23 pm
RSW
- CLT
1 stop8h 08m
Frontier
Sun 5/1710:39 pm
CLT
- RSW
1 stop12h 06m
Frontier
Deal found 2/20![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:01 am
RSW
- CLT
1 stop22h 19m
Frontier
Mon 4/1310:28 pm
CLT
- RSW
1 stop10h 45m
Frontier
Deal found 2/18![Frontier logo]()
$191
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:02 am
RSW
- CLT
1 stop5h 57m
Frontier
Mon 3/23:03 pm
CLT
- RSW
1 stop5h 33m
Frontier
Deal found 2/19![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:10 pm
RSW
- CLT
2 stops12h 53m
Multiple Airlines
Sun 3/2210:42 pm
CLT
- RSW
1 stop24h 42m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:29 pm
RSW
- CLT
1 stop10h 42m
Multiple Airlines
Sun 3/810:46 pm
CLT
- RSW
1 stop12h 30m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:17 pm
RSW
- CLT
2 stops30h 57m
Multiple Airlines
Mon 4/2710:39 pm
CLT
- RSW
1 stop12h 06m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$222
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1311:47 am
RSW
- CLT
1 stop9h 00m
Frontier
Mon 3/1610:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/19![Frontier logo]()
$224
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:51 pm
RSW
- CLT
1 stop25h 55m
Frontier
Sun 4/2610:07 pm
CLT
- RSW
1 stop12h 38m
Frontier
Deal found 2/20![Frontier logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:10 pm
RSW
- CLT
2 stops25h 41m
Multiple Airlines
Mon 3/2310:58 pm
CLT
- RSW
1 stop11h 39m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$229
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:39 pm
RSW
- CLT
1 stop10h 32m
Frontier
Sat 3/2110:47 pm
CLT
- RSW
1 stop12h 05m
Frontier
Deal found 2/20![Frontier logo]()
$230
Best flights from Fort Myers to SpartanburgDiscover carefully curated flight deals from Fort Myers to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2026.
Discover carefully curated flight deals from Fort Myers to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2026.
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:23 pm
RSW
- CLT
1 stop8h 08m
Frontier
Mon 4/2710:39 pm
CLT
- RSW
1 stop12h 06m
Frontier
Deal found 2/18![Frontier logo]()
$181
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:10 pm
RSW
- CLT
3 stops28h 07m
Spirit Airlines
Wed 3/183:55 pm
CLT
- RSW
3 stops23h 10m
Spirit Airlines
Deal found 2/17![Spirit Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:00 am
RSW
- CLT
1 stop15h 57m
Multiple Airlines
Thu 3/129:17 pm
CLT
- RSW
2 stops21h 13m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/111:00 pm
RSW
- CLT
1 stop5h 14m
Delta
Tue 7/2110:07 am
CLT
- RSW
1 stop3h 48m
Delta
Deal found 2/17![Delta logo]()
$331
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:29 pm
RSW
- CLT
1 stop10h 42m
Frontier
Mon 3/2310:49 pm
CLT
- RSW
1 stop12h 03m
Frontier
Deal found 2/19![Frontier logo]()
$224
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:39 pm
RSW
- CLT
1 stop10h 32m
Frontier
Sun 3/2210:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/18![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:40 am
RSW
- CLT
1 stop11h 12m
Frontier
Sun 4/192:57 pm
CLT
- RSW
2 stops19h 48m
Frontier
Deal found 2/18![Frontier logo]()
$235
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:02 am
RSW
- CLT
1 stop5h 57m
Frontier
Sun 3/1510:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/19![Frontier logo]()
$240
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
RSW
- CLT
3 stops28h 17m
Spirit Airlines
Sun 3/159:17 pm
CLT
- RSW
2 stops17h 48m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/81:00 pm
RSW
- CLT
1 stop5h 14m
Delta
Wed 7/225:30 am
CLT
- RSW
1 stop6h 29m
Delta
Deal found 2/17![Delta logo]()
$331
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:50 am
RSW
- CLT
1 stop6h 39m
Delta
Tue 6/1610:07 am
CLT
- RSW
1 stop6h 28m
Delta
Deal found 2/19![Delta logo]()
$331
Last-minute flights from Fort Myers to SpartanburgDiscover last-minute flight deals from Fort Myers to Spartanburg. Data last updated February 20, 2026 and is based on user searches.
Discover last-minute flight deals from Fort Myers to Spartanburg. Data last updated February 20, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:02 am
RSW
- CLT
1 stop5h 57m
Frontier
Mon 3/23:03 pm
CLT
- RSW
1 stop5h 33m
Frontier
Deal found 2/16![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/38:09 pm
RSW
- CLT
2 stops41h 45m
Frontier
Mon 3/910:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/18![Frontier logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:29 pm
RSW
- CLT
1 stop10h 42m
Multiple Airlines
Sun 3/810:46 pm
CLT
- RSW
1 stop12h 30m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:29 pm
RSW
- CLT
1 stop10h 42m
Frontier
Tue 3/107:48 pm
CLT
- RSW
2 stops22h 27m
Frontier
Deal found 2/17![Frontier logo]()
$236
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:02 am
RSW
- CLT
1 stop5h 57m
Frontier
Sun 3/1510:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/19![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 am
RSW
- CLT
1 stop16h 13m
Multiple Airlines
Sun 3/158:56 am
CLT
- RSW
2 stops33h 34m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$241
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/1311:47 am
RSW
- CLT
1 stop9h 00m
Frontier
Mon 3/1610:39 pm
CLT
- RSW
1 stop12h 13m
Frontier
Deal found 2/19![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:10 pm
RSW
- CLT
2 stops12h 53m
Multiple Airlines
Sun 3/2210:42 pm
CLT
- RSW
1 stop24h 42m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:10 pm
RSW
- CLT
2 stops25h 41m
Multiple Airlines
Mon 3/2310:58 pm
CLT
- RSW
1 stop11h 39m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$229
This Expedia deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:39 pm
RSW
- CLT
1 stop10h 32m
Frontier
Sat 3/2110:47 pm
CLT
- RSW
1 stop12h 05m
Frontier
Deal found 2/20![Frontier logo]()
$230
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/219:29 pm
RSW
- CLT
1 stop10h 42m
Frontier
Thu 3/267:43 pm
CLT
- RSW
1 stop20h 48m
Frontier
Deal found 2/19![Frontier logo]()
$235
One-way flights from Fort Myers to SpartanburgSearch for one-way flight options from Fort Myers to Spartanburg. Find affordable one-way fares based on user searches. Data last updated February 20, 2026.
Search for one-way flight options from Fort Myers to Spartanburg. Find affordable one-way fares based on user searches. Data last updated February 20, 2026.
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:23 pm
RSW
- CLT
1 stop8h 08m
Frontier
Deal found 2/18![Frontier logo]()
$80
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:40 am
RSW
- CLT
1 stop11h 12m
Frontier
Deal found 2/20![Frontier logo]()
$86
This Trip.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:28 pm
RSW
- CLT
1 stop23h 24m
Frontier
Deal found 2/18![Frontier logo]()
$89
This Frontier deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:02 am
RSW
- CLT
1 stop5h 57m
Frontier
Deal found 2/18![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:31 pm
RSW
- CLT
1 stop19h 28m
Frontier
Deal found 2/17![Frontier logo]()
$103
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:40 am
RSW
- CLT
1 stop11h 12m
Frontier
Deal found 2/20![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/258:09 pm
RSW
- CLT
1 stop14h 06m
Frontier
Deal found 2/17![Frontier logo]()
$108
This Frontier deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:47 am
RSW
- CLT
1 stop9h 05m
Frontier
Deal found 2/16![Frontier logo]()
$109
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:35 am
RSW
- CLT
2 stops16h 18m
Spirit Airlines
Deal found 2/17![Spirit Airlines logo]()
$113
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:25 am
RSW
- CLT
1 stop12h 20m
Southwest
Deal found 2/18![Southwest logo]()
$114
Find flight deals from Fort Myers to Spartanburg
Keep the following information in mind while searching for Fort Myers to Spartanburg flight deals. Data was last updated February 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $160 (Travelocity) |
One-way from | $80 (Frontier) |
Popular in | August |
Cheapest in | September |
Average price | $415 |
Cheapflights Fare Finder
Customize your flight search to find flights from Fort Myers to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Fort Myers to Spartanburg that are best for you.
Fly from
Fort Myers
Fly to
Spartanburg
Route
Depart
Return
Price
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Thu 4/23
12:23 pm-8:31 pm
1 stop8h 08m
Charlotte Douglas
Mon 4/27
10:39 pm-10:45 am
1 stop12h 06m
$181
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Sat 3/21
9:29 pm-8:11 am
1 stop10h 42m
Charlotte Douglas
Mon 3/23
10:49 pm-10:52 am
1 stop12h 03m
$224
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Fri 3/20
9:39 pm-8:11 am
1 stop10h 32m
Charlotte Douglas
Sun 3/22
10:39 pm-10:52 am
1 stop12h 13m
$230
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Thu 4/16
11:40 am-10:52 pm
1 stop11h 12m
Charlotte Douglas
Sun 4/19
2:57 pm-10:45 am
2 stops19h 48m
$235
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Thu 3/5
11:02 am-4:59 pm
1 stop5h 57m
Charlotte Douglas
Sun 3/15
10:39 pm-10:52 am
1 stop12h 13m
$240
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Mon 3/16
4:10 pm-8:17 pm
3 stops28h 07m
Charlotte Douglas
Wed 3/18
3:55 pm-3:05 pm
3 stops23h 10m
$292
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Sun 3/8
6:00 am-9:57 pm
1 stop15h 57m
Charlotte Douglas
Thu 3/12
9:17 pm-6:30 pm
2 stops21h 13m
$311
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Thu 3/5
6:00 am-10:17 am
3 stops28h 17m
Charlotte Douglas
Sun 3/15
9:17 pm-3:05 pm
2 stops17h 48m
$322
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Sat 7/11
1:00 pm-6:14 pm
1 stop5h 14m
Charlotte Douglas
Tue 7/21
10:07 am-1:55 pm
1 stop3h 48m
$331
Fort MyersCharlotte
RSW - CLT
RSWCLT
Fort Myers SW Florida Intl
Wed 7/8
1:00 pm-6:14 pm
1 stop5h 14m
Charlotte Douglas
Wed 7/22
5:30 am-11:59 am
1 stop6h 29m
$331
Showing 1-10 of 23 results
Best time to book a flight from Fort Myers to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Fort Myers with our price prediction graph.
RSW-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Fort Myers to Spartanburg
RSW-SB1
RSW-CLT
How far ahead should I book a flight from Fort Myers to Spartanburg?
Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to Spartanburg. Price data was last updated on February 20, 2026.
The best time to book flights from Fort Myers to Spartanburg is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Fort Myers to Spartanburg?
Currently, May is the cheapest month in which you can book a flight from Fort Myers to Spartanburg (average of $39). Flying from Fort Myers to Spartanburg in February is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from RSW to SB1?
Find hourly flight availability from Fort Myers to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2026.
A simple way to save on the total cost of your ticket is to fly from Fort Myers to Spartanburg in the evening. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the afternoon.
What is the cheapest day to fly from Fort Myers to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Spartanburg. Price data was last updated on February 17, 2026.
Travelers seeking maximum savings on their Fort Myers to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Fort Myers to Spartanburg
Explore weekly flight availability from Fort Myers to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2026.
The most flights from RSW to SB1 are scheduled on a Monday (11 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (8 on average).
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated February 20, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Boarding
8.1
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Fort Myers to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Fort Myers to Spartanburg
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Fort Myers to Spartanburg by cabin class
Find flights from Fort Myers to Spartanburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Fort Myers and Spartanburg flights
Browse other Fort Myers and Spartanburg flight options. Last updated on February 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fort Myers to Spartanburg flights
Consider these flights traveling from Fort Myers to Spartanburg.
Top 5 airlines flying from Fort Myers to Spartanburg
Discover the top 5 airlines that operate flights from Fort Myers to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$62 | Average$162 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$81 | Average$188 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$155 | Average$331 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$159 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$167 | Average$373 | FlexibilityNo cancel fee | On-time63% |