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Spartanburg

$80+ Cheap flights from Fort Myers (RSW) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — CLT
Mar 25 — Apr 11
Wed 3/25
Wed 4/1
1 adult, Economy
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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Spartanburg are usually found in September or October, booked 27 days in advance, depart on a Wednesday or Friday and return on a Sunday

Cheap flight deals from Fort Myers to Spartanburg

Cheapest flights from Fort Myers to Spartanburg
Explore the most affordable flight options available from Fort Myers to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.

This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:40 am
RSW
-
CLT
1 stop11h 12m
Frontier
Sun 5/107:49 pm
CLT
-
RSW
1 stop20h 40m
Frontier
Deal found 2/19$160
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:23 pm
RSW
-
CLT
1 stop8h 08m
Frontier
Sun 5/1710:39 pm
CLT
-
RSW
1 stop12h 06m
Frontier
Deal found 2/20$181
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:39 pm
RSW
-
CLT
1 stop10h 32m
Multiple Airlines
Mon 3/2310:58 pm
CLT
-
RSW
1 stop11h 39m
Multiple Airlines
Deal found 2/20$201
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:31 pm
RSW
-
CLT
1 stop10h 30m
Frontier
Mon 3/23:03 pm
CLT
-
RSW
1 stop5h 33m
Frontier
Deal found 2/19$202
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/59:29 pm
RSW
-
CLT
1 stop10h 42m
Frontier
Mon 3/910:39 pm
CLT
-
RSW
1 stop12h 13m
Frontier
Deal found 2/22$213
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:10 pm
RSW
-
CLT
2 stops12h 53m
Multiple Airlines
Sun 3/2210:42 pm
CLT
-
RSW
1 stop24h 42m
Multiple Airlines
Deal found 2/19$214
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:39 pm
RSW
-
CLT
1 stop10h 32m
Multiple Airlines
Sun 3/2210:42 pm
CLT
-
RSW
1 stop24h 42m
Multiple Airlines
Deal found 2/20$221
This Expedia deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:39 pm
RSW
-
CLT
1 stop10h 32m
Frontier
Fri 3/2010:39 pm
CLT
-
RSW
1 stop12h 13m
Frontier
Deal found 2/22$224
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:39 pm
RSW
-
CLT
1 stop10h 32m
Frontier
Tue 3/107:48 pm
CLT
-
RSW
2 stops22h 27m
Frontier
Deal found 2/21$226
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:41 pm
RSW
-
CLT
1 stop24h 11m
Multiple Airlines
Mon 3/3010:52 pm
CLT
-
RSW
1 stop11h 45m
Multiple Airlines
Deal found 2/23$227

Find flight deals from Fort Myers to Spartanburg

Keep the following information in mind while searching for Fort Myers to Spartanburg flight deals. Data was last updated February 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(Expedia)

One-way from

$80
(Frontier)

Popular in

August

Cheapest in

September

Average price

$415
Provider with most accurate pricing for Fort Myers SW Florida Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Charlotte Douglas flights.
Search Deals
From Fort Myers SW Florida Intl to Spartanburg
Search Deals
One-way flight from Fort Myers SW Florida Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Fort Myers to Spartanburg that are best for you.

Fly from

Fort Myers

Fly to

Spartanburg

Route

Depart

Return

Price

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 3/18

7:10 pm-8:03 am

2 stops12h 53m

Charlotte Douglas

Sun 3/22

10:42 pm-11:24 pm

1 stop24h 42m

$214

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 5/7

11:40 am-8:05 am

1 stop20h 25m

Charlotte Douglas

Sun 5/10

10:31 pm-11:08 pm

2 stops24h 37m

$248

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 3/19

11:47 am-12:38 am

2 stops12h 51m

Charlotte Douglas

Sun 3/22

10:42 pm-11:24 pm

1 stop24h 42m

$259

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 3/18

7:10 pm-8:51 pm

2 stops25h 41m

Charlotte Douglas

Tue 3/24

10:39 pm-10:52 am

1 stop12h 13m

$263

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Tue 3/24

7:35 am-11:53 pm

2 stops16h 18m

Charlotte Douglas

Wed 3/25

7:00 am-6:19 pm

2 stops11h 19m

$267

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 3/18

9:54 pm-9:57 pm

1 stop24h 03m

Charlotte Douglas

Mon 3/23

10:58 pm-10:37 am

1 stop11h 39m

$298

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 3/19

10:43 am-8:11 am

1 stop21h 28m

Charlotte Douglas

Mon 3/23

10:58 pm-10:37 am

1 stop11h 39m

$298

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 3/20

9:39 pm-8:11 am

1 stop10h 32m

Charlotte Douglas

Sun 3/22

7:00 am-12:43 am

2 stops17h 43m

$317

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 5/6

3:00 pm-8:44 pm

1 stop5h 44m

Charlotte Douglas

Tue 5/12

5:35 am-9:47 am

1 stop4h 12m

$331

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Sun 3/1

6:00 am-2:54 pm

1 stop8h 54m

Charlotte Douglas

Tue 3/3

5:54 pm-12:01 pm

2 stops18h 07m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Showing 1-10 of 22 results
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Best time to book a flight from Fort Myers to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Spartanburg

How far ahead should I book a flight from Fort Myers to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to Spartanburg. Price data was last updated on February 20, 2026.

The best time to book flights from Fort Myers to Spartanburg is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to Spartanburg?

Currently, May is the cheapest month in which you can book a flight from Fort Myers to Spartanburg (average of $39). Flying from Fort Myers to Spartanburg in February is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to SB1?

Find hourly flight availability from Fort Myers to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2026.

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Spartanburg in the evening. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Fort Myers to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Spartanburg. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Fort Myers to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated February 23, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,300 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,300 reviews
Southwest
8.0
Very good
4,300 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,236 reviews
Southwest
8.0
Very good
4,300 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,339 reviews
Southwest
8.0
Very good
4,300 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,489 reviews
Southwest
8.0
Very good
4,300 reviews

Crew

8.6

Entertainment

7.5

Boarding

8.1

Overall

8.0

Comfort

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Spartanburg?

    Fort Myers SW Florida Intl (RSW), located 10.0 mi from the city center, is the airport you fly out of when you book flights from Fort Myers to Spartanburg. 5 airlines have flights from SW Florida Intl to Spartanburg on a regular basis. Booking flights from Fort Myers SW Florida Intl to Spartanburg should not be difficult; the airport handles an average of 7 outbound flights to Spartanburg per day.

  • How popular is this Fort Myers to Spartanburg flight route?

    This flight path from Fort Myers SW Florida Intl to Spartanburg was viewed by 18 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Fort Myers to Spartanburg?

    Departing from Fort Myers to Spartanburg will take you 16h 18m. The distance from Fort Myers to Spartanburg is about 601 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Fort Myers to Spartanburg one-way?

    One-way options have recently been found by users for as low as $48 on Spirit Airlines. Other airlines that offer cheap prices include Frontier from $60 and Delta from $89 one-way.

  • What are the cheapest flights from Fort Myers to Spartanburg?

    The cheapest flight price from Fort Myers to Spartanburg is $104. On average you can expect to pay $1,303. The most popular route, (Fort Myers SW Florida Intl - Charlotte Douglas), can usually be booked for $233.

  • Can I find deals for flights from Fort Myers to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Spartanburg.

  • Can I find deals for business class flights from Fort Myers to Spartanburg?

    Yes. Cheapflights offers flight deals from Fort Myers to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Spartanburg?

    Currently, May is the cheapest month in which you can book a flight from Fort Myers to Spartanburg (average of $39). Flying from Fort Myers to Spartanburg in February is currently the most expensive (average of $86). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Fort Myers to Spartanburg

Discover the top 5 airlines that operate flights from Fort Myers to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$62Average$162FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$81Average$190FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$155Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$159Average$384FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$167Average$373FlexibilityNo cancel feeOn-time63%

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