HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spartanburg

$77+ Cheap flights from Fort Myers (RSW) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — CLT
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Fort Myers to Spartanburg with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Spartanburg are usually found in September or October, booked 26 days in advance, depart on a Wednesday or Friday and return on a Sunday

Cheap flight deals from Fort Myers to Spartanburg

Cheapest flights from Fort Myers to Spartanburg
Explore the most affordable flight options available from Fort Myers to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

This Expedia deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:55 amRSW - CLT
1 stop7h 13mFrontier
Fri 1/211:38 amCLT - RSW
1 stop11h 41mFrontier
Deal found 12/24$357
This Southwest deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:10 pmRSW - CLT
1 stop6h 50mSouthwest
Thu 1/18:30 amCLT - RSW
1 stop6h 30mSouthwest
Deal found 12/26$488
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:30 amRSW - CLT
1 stop12h 03mMultiple Airlines
Wed 12/315:14 pmCLT - RSW
1 stop17h 04mMultiple Airlines
Deal found 12/25$493
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/281:13 pmRSW - CLT
1 stop28h 20mMultiple Airlines
Sun 1/49:07 amCLT - RSW
1 stop11h 53mMultiple Airlines
Deal found 12/26$514
This Delta deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amRSW - CLT
1 stop5h 46mDelta
Tue 12/306:00 amCLT - RSW
1 stop3h 46mDelta
Deal found 12/24$527
This Southwest deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:05 pmRSW - CLT
2 stops9h 55mSouthwest
Fri 1/21:20 pmCLT - RSW
2 stops9h 30mSouthwest
Deal found 12/24$534
This Southwest deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:05 amRSW - CLT
2 stops9h 55mSouthwest
Wed 12/3112:55 pmCLT - RSW
1 stop8h 50mSouthwest
Deal found 12/25$535
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amRSW - CLT
Nonstop2h 02mAmerican Airlines
Thu 1/14:48 pmCLT - RSW
Nonstop1h 59mAmerican Airlines
Deal found 12/26$542
This Southwest deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:05 pmRSW - CLT
1 stop7h 45mSouthwest
Mon 12/295:45 amCLT - RSW
1 stop10h 00mSouthwest
Deal found 12/24$554
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amRSW - CLT
Nonstop2h 02mAmerican Airlines
Sun 1/411:00 amCLT - RSW
Nonstop2h 00mAmerican Airlines
Deal found 12/26$557

Find flight deals from Fort Myers to Spartanburg

Keep the following information in mind while searching for Fort Myers to Spartanburg flight deals. Data was last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$151
(Kiwi.com)

One-way from

$77
(Kiwi.com)

Popular in

August

Cheapest in

September

Average price

$349
Provider with most accurate pricing for Fort Myers SW Florida Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Charlotte Douglas flights.
Search Deals
From Fort Myers SW Florida Intl to Spartanburg
Search Deals
One-way flight from Fort Myers SW Florida Intl to Spartanburg
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Fort Myers to Spartanburg that are best for you.

Fly from

Fort Myers

Fly to

Spartanburg

Route

Depart

Return

Price

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 1/16

10:02 am-11:28 am

1 stop25h 26m

Charlotte Douglas

Sun 1/18

2:05 pm-11:24 pm

1 stop9h 19m

$166

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 1/23

9:11 pm-10:00 am

1 stop12h 49m

Charlotte Douglas

Fri 1/30

9:59 pm-11:07 am

2 stops37h 08m

$191

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 1/16

10:02 am-11:28 am

1 stop25h 26m

Charlotte Douglas

Mon 1/19

12:30 pm-11:01 am

1 stop22h 31m

$195

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 1/14

7:45 pm-10:31 am

1 stop14h 46m

Charlotte Douglas

Sat 1/17

3:15 pm-1:39 pm

2 stops22h 24m

$226

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 1/8

1:00 pm-8:34 pm

1 stop7h 34m

Charlotte Douglas

Thu 1/8

9:34 pm-11:33 pm

Nonstop1h 59m

$288

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Sat 1/10

7:31 am-11:59 pm

2 stops16h 28m

Charlotte Douglas

Wed 1/14

7:43 pm-6:40 pm

2 stops22h 57m

$333

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 2/11

1:05 pm-7:55 pm

1 stop6h 50m

Charlotte Douglas

Sat 2/14

3:20 pm-9:35 pm

1 stop6h 15m

$355

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 1/14

8:15 am-12:40 pm

1 stop4h 25m

Charlotte Douglas

Sat 1/17

1:05 pm-6:40 pm

1 stop5h 35m

$355

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Sat 5/23

8:10 am-1:06 pm

1 stop4h 56m

Charlotte Douglas

Sat 5/30

4:30 pm-9:17 pm

1 stop4h 47m

$369

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 3/18

9:13 am-8:21 am

2 stops23h 08m

Charlotte Douglas

Fri 3/20

10:39 pm-10:52 am

1 stop12h 13m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 22 results
1
2
3

Best time to book a flight from Fort Myers to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Spartanburg

How far ahead should I book a flight from Fort Myers to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to Spartanburg. Price data was last updated on December 19, 2025.

The best time to book flights from Fort Myers to Spartanburg is 26 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Fort Myers to Spartanburg?

Currently, May is the cheapest month in which you can book a flight from Fort Myers to Spartanburg (average of $39). Flying from Fort Myers to Spartanburg in November is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to SB1?

Find hourly flight availability from Fort Myers to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Spartanburg in the evening. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Fort Myers to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Fort Myers to Spartanburg flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Fort Myers to Spartanburg

Explore weekly flight availability from Fort Myers to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 26, 2025.

The most flights from RSW to SB1 are scheduled on a Monday (9 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (7 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated December 26, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Fort Myers to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,013 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,064 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,206 reviews
Southwest
8.0
Very good
4,258 reviews

Boarding

8.1

Entertainment

7.5

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Spartanburg?

    Fort Myers SW Florida Intl (RSW), located 10.0 mi from the city center, is the airport you fly out of when you book flights from Fort Myers to Spartanburg. 5 airlines have flights from SW Florida Intl to Spartanburg on a regular basis. Booking flights from Fort Myers SW Florida Intl to Spartanburg should not be difficult; the airport handles an average of 8 outbound flights to Spartanburg per day.

  • How popular is this Fort Myers to Spartanburg flight route?

    This flight path from Fort Myers SW Florida Intl to Spartanburg was viewed by 15 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Fort Myers to Spartanburg?

    Departing from Fort Myers to Spartanburg will take you 12h 49m. The distance from Fort Myers to Spartanburg is about 601 mi.

  • What are the cheapest airlines to fly from Fort Myers to Spartanburg one-way?

    One-way options have recently been found by users for as low as $48 on Spirit Airlines. Other airlines that offer cheap prices include Southwest from $89 and Delta from $92 one-way.

  • What are the cheapest flights from Fort Myers to Spartanburg?

    The cheapest flight price from Fort Myers to Spartanburg is $108. On average you can expect to pay $829. The most popular route, (Fort Myers SW Florida Intl - Charlotte Douglas), can usually be booked for $168.

  • Can I find deals for flights from Fort Myers to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Spartanburg.

  • Can I find deals for business class flights from Fort Myers to Spartanburg?

    Yes. Cheapflights offers flight deals from Fort Myers to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Spartanburg?

    Currently, May is the cheapest month in which you can book a flight from Fort Myers to Spartanburg (average of $39). Flying from Fort Myers to Spartanburg in November is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
Fort Lauderdale to Charlotte flights
Miami to Charlotte flights
Orlando to Charlotte flights
Tampa to Charlotte flights
West Palm Beach to Charlotte flights
Tampa to Charleston flights
Fort Lauderdale to Charleston flights
Jacksonville to Charlotte flights
Pensacola to Charlotte flights
Miami to Savannah flights
Fort Myers to Charlotte flights
Miami to Charleston flights
Orlando to Charleston flights
Fort Lauderdale to Savannah flights
Fort Myers to Charleston flights
Sarasota to Charlotte flights
Orlando to Savannah flights
Tampa to Greenville flights
Orlando to Columbia flights
West Palm Beach to Savannah flights
Tallahassee to Columbia flights
Tampa to Savannah flights
Miami to Greenville flights
Tampa to Columbia flights
Tampa to Myrtle Beach flights
Orlando to Myrtle Beach flights
Fort Myers to Greenville flights
Fort Lauderdale to Myrtle Beach flights
Fort Lauderdale to Columbia flights
Sarasota to Savannah flights
Orlando to Greenville flights
Gainesville to Charlotte flights
Sarasota to Myrtle Beach flights
Key West to Charlotte flights
Fort Myers to Myrtle Beach flights
Pensacola to Charleston flights
Tallahassee to Charlotte flights
Fort Myers to Savannah flights
Pensacola to Greenville flights
Sarasota to Greenville flights
Jacksonville to Myrtle Beach flights
West Palm Beach to Greenville flights
West Palm Beach to Charleston flights
Miami to Columbia flights
West Palm Beach to Myrtle Beach flights
Sarasota to Charleston flights
Melbourne to Charlotte flights
West Palm Beach to Columbia flights
Pensacola to Savannah flights
Pensacola to Columbia flights

Top 5 airlines flying from Fort Myers to Spartanburg

Discover the top 5 airlines that operate flights from Fort Myers to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$62Average$197FlexibilityNo cancel feeOn-time65%
Breeze AirwaysCheapest$91Average$188FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$155Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$159Average$363FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$167Average$373FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.