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Spartanburg

$133+ Cheap flights from Fort Myers (RSW) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/17. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — CLT
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Spartanburg are usually found in September or October, booked 60 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Fort Myers to Spartanburg

Cheapest flights from Fort Myers to Spartanburg
Explore the most affordable flight options available from Fort Myers to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
RSW
-
CLT
1 stop5h 35m
Southwest
Sat 5/303:50 pm
CLT
-
RSW
1 stop4h 15m
Southwest
Deal found 5/21$319
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:50 am
RSW
-
CLT
1 stop6h 30m
Southwest
Sat 5/307:05 am
CLT
-
RSW
1 stop5h 00m
Southwest
Deal found 5/20$345
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:35 am
RSW
-
CLT
1 stop7h 00m
Southwest
Wed 6/2410:40 am
CLT
-
RSW
1 stop7h 35m
Southwest
Deal found 5/20$349
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/299:00 am
RSW
-
CLT
1 stop9h 20m
Southwest
Sat 5/3010:55 am
CLT
-
RSW
2 stops8h 30m
Southwest
Deal found 5/20$356
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:50 pm
RSW
-
CLT
1 stop4h 50m
Southwest
Tue 6/26:40 am
CLT
-
RSW
1 stop7h 25m
Southwest
Deal found 5/20$359
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:05 am
RSW
-
CLT
2 stops12h 40m
Southwest
Sat 6/2011:35 am
CLT
-
RSW
1 stop7h 35m
Southwest
Deal found 5/21$370
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/279:59 am
RSW
-
CLT
Nonstop2h 03m
American Airlines
Sat 7/47:11 am
CLT
-
RSW
Nonstop1h 58m
American Airlines
Deal found 5/20$371

Find flight deals from Fort Myers to Spartanburg

Keep the following information in mind while searching for Fort Myers to Spartanburg flight deals. Data was last updated May 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$319
(Southwest)

One-way from

$133
(Kiwi.com)

Popular in

August

Cheapest in

September

Average price

$457
Provider with most accurate pricing for Fort Myers SW Florida Intl-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Charlotte Douglas flights.
Search Deals
From Fort Myers SW Florida Intl to Spartanburg
Search Deals
One-way flight from Fort Myers SW Florida Intl to Spartanburg
Search Deals
High demand for flights, 3% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Fort Myers to Spartanburg that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 5/29

12:55 pm-10:40 pm

1 stop9h 45m

Charlotte Douglas

Sat 5/30

8:10 am-3:45 pm

1 stop7h 35m

$350

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 7/9

2:05 pm-9:40 pm

1 stop7h 35m

Charlotte Douglas

Mon 7/13

4:40 pm-11:25 pm

1 stop6h 45m

$399

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 8/20

6:50 am-4:25 pm

2 stops9h 35m

Charlotte Douglas

Tue 8/25

11:10 am-10:10 pm

2 stops11h 00m

$403

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 6/5

5:10 am-4:00 pm

1 stop10h 50m

Charlotte Douglas

Fri 6/12

4:40 pm-11:25 pm

1 stop6h 45m

$404

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 7/3

2:05 pm-9:40 pm

1 stop7h 35m

Charlotte Douglas

Sun 7/5

6:30 am-6:25 pm

2 stops11h 55m

$409

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Sat 6/6

8:05 am-8:45 pm

2 stops12h 40m

Charlotte Douglas

Wed 6/10

11:50 am-10:00 pm

2 stops10h 10m

$415

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Thu 6/25

6:15 am-4:00 pm

2 stops9h 45m

Charlotte Douglas

Sat 6/27

1:00 pm-10:55 pm

2 stops9h 55m

$428

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Tue 5/26

7:20 am-5:45 pm

2 stops10h 25m

Charlotte Douglas

Tue 6/2

6:40 am-3:40 pm

2 stops9h 00m

$437
Quickest round-trip

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Fri 6/19

1:19 pm-8:20 pm

1 stop7h 01m

Charlotte Douglas

Tue 6/23

6:59 am-12:14 pm

1 stop5h 15m

$439

Fort MyersCharlotte

RSW - CLT

RSWCLT

Fort Myers SW Florida Intl

Wed 6/10

6:10 am-3:40 pm

2 stops9h 30m

Charlotte Douglas

Sun 6/14

10:50 am-10:00 pm

2 stops11h 10m

$447

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/22

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Best time to book a flight from Fort Myers to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Spartanburg

What is the cheapest time of day to fly from RSW to SB1?

Find hourly flight availability from Fort Myers to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 22, 2026.

A simple way to save on the total cost of your ticket is to fly from Fort Myers to Spartanburg in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight at noon.

Weekly flight availability from Fort Myers to Spartanburg

Explore weekly flight availability from Fort Myers to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 22, 2026.

The most flights from RSW to SB1 are scheduled on a Monday (6 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Fort Myers to Spartanburg?

What is the cheapest day to fly from Fort Myers to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Spartanburg. Price data was last updated on May 16, 2026.

Travelers seeking maximum savings on their Fort Myers to Spartanburg flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated May 22, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Fort Myers to Spartanburg to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,277 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

7.9

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,277 reviews
Southwest
7.9
Good
4,277 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

7.9

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,644 reviews
Southwest
7.9
Good
4,277 reviews

Crew

8.6

Food

7.0

Comfort

8.0

Overall

7.9

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Fort Myers to Spartanburg?

    Fort Myers SW Florida Intl (RSW), located 10.0 mi from the city center, is the airport you fly out of when you book flights from Fort Myers to Spartanburg. 4 airlines have flights from SW Florida Intl to Spartanburg on a regular basis. Booking flights from Fort Myers SW Florida Intl to Spartanburg should not be difficult; the airport handles an average of 5 outbound flights to Spartanburg per day.

  • How popular is this Fort Myers to Spartanburg flight route?

    This flight path from Fort Myers SW Florida Intl to Spartanburg was viewed by 41 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Fort Myers to Spartanburg?

    Departing from Fort Myers to Spartanburg will take you 9h 45m. The distance from Fort Myers to Spartanburg is about 601 mi.

  • What are the cheapest airlines to fly from Fort Myers to Spartanburg one-way?

    One-way options have recently been found by users for as low as $60 on Frontier. Other airlines that offer cheap prices include Delta from $89 and Southwest from $89 one-way.

  • What are the cheapest flights from Fort Myers to Spartanburg?

    The cheapest flight price from Fort Myers to Spartanburg is $118. On average you can expect to pay $1,055. The most popular route, (Fort Myers SW Florida Intl - Charlotte Douglas), can usually be booked for $319.

  • Can I find deals for flights from Fort Myers to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Spartanburg.

  • Can I find deals for business class flights from Fort Myers to Spartanburg?

    Yes. Cheapflights offers flight deals from Fort Myers to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 4 airlines flying from Fort Myers to Spartanburg

Discover the top 4 airlines that operate flights from Fort Myers to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$128Average$198FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$155Average$337FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$159Average$381FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$167Average$430FlexibilityNo cancel feeOn-time63%

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