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$78+ Cheap flights from Buffalo (BUF) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/25. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CLT
Oct 31 — Nov 71
Fri 10/31
Fri 11/7
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Spartanburg are usually found in January or November, booked 77 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Buffalo to Spartanburg

Keep the following information in mind while searching for Buffalo to Spartanburg flight deals. Data was last updated October 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$253
(Kiwi.com)

One-way from

$78
(Priceline)

Popular in

December

Cheapest in

January

Average price

$293
Provider with most accurate pricing for Buffalo-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Charlotte Douglas flights.
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From Buffalo to Spartanburg
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One-way flight from Buffalo to Spartanburg
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High demand for flights, 13% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Buffalo to Spartanburg

Cheapest flights from Buffalo to Spartanburg
Explore the most affordable flight options available from Buffalo to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:14 pmBUF - CLT
1 stop17h 06mMultiple Airlines
Fri 10/3112:18 pmCLT - BUF
1 stop21h 50mMultiple Airlines
Deal found 9/30$253
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:32 amBUF - CLT
Nonstop2h 03mAmerican Airlines
Sat 11/811:00 amCLT - BUF
1 stop12h 17mAmerican Airlines
Deal found 10/1$255
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:30 pmBUF - CLT
Nonstop2h 02mAmerican Airlines
Wed 11/56:03 pmCLT - BUF
1 stop4h 53mAmerican Airlines
Deal found 9/29$257
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/56:00 amBUF - CLT
1 stop6h 05mAmerican Airlines
Sat 11/810:25 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Deal found 10/1$260
This Frontier deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:24 pmBUF - CLT
2 stops20h 08mFrontier
Mon 11/39:57 amCLT - BUF
2 stops11h 11mFrontier
Deal found 9/29$261
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:30 amBUF - CLT
Nonstop1h 59mAmerican Airlines
Thu 10/3010:39 amCLT - BUF
Nonstop1h 45mAmerican Airlines
Deal found 9/30$266
This Delta deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:20 amBUF - CLT
1 stop5h 51mDelta
Wed 11/55:00 pmCLT - BUF
1 stop5h 57mDelta
Deal found 10/1$267
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:14 pmBUF - CLT
1 stop17h 06mMultiple Airlines
Thu 11/69:34 amCLT - BUF
2 stops10h 35mMultiple Airlines
Deal found 9/29$269
This Delta deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:05 pmBUF - CLT
1 stop5h 58mDelta
Wed 11/55:25 pmCLT - BUF
1 stop5h 27mDelta
Deal found 9/30$270
This Southwest deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:30 amBUF - CLT
1 stop4h 25mSouthwest
Wed 10/222:00 pmCLT - BUF
2 stops8h 15mSouthwest
Deal found 10/1$272
This Delta deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:21 amBUF - CLT
1 stop6h 43mDelta
Wed 12/176:00 amCLT - BUF
1 stop6h 34mDelta
Deal found 9/29$273
This Southwest deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amBUF - CLT
1 stop7h 25mSouthwest
Wed 11/56:10 amCLT - BUF
2 stops8h 10mSouthwest
Deal found 9/29$274

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 1, 2025.
Use the filters below to find and compare flights from Buffalo to Spartanburg that are best for you.

Fly from

Buffalo

Fly to

Spartanburg

Route

Depart

Return

Price

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 11/4

6:03 am-12:30 pm

1 stop6h 27m

Charlotte Douglas

Wed 11/5

9:15 am-1:47 pm

1 stop4h 32m

$267

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 11/4

6:03 am-11:10 am

1 stop5h 07m

Charlotte Douglas

Tue 11/4

5:25 pm-10:52 pm

1 stop5h 27m

$267

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 12/12

1:00 pm-3:03 pm

Nonstop2h 03m

Charlotte Douglas

Tue 12/16

9:41 pm-11:24 pm

Nonstop1h 43m

$270

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 11/1

5:05 pm-11:03 pm

1 stop5h 58m

Charlotte Douglas

Wed 11/5

5:25 pm-10:52 pm

1 stop5h 27m

$270

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 10/29

6:00 am-1:15 pm

1 stop7h 15m

Charlotte Douglas

Wed 11/5

6:40 am-2:20 pm

2 stops7h 40m

$272

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 2/28

4:00 pm-10:23 pm

1 stop6h 23m

Charlotte Douglas

Tue 3/3

6:59 pm-11:49 pm

1 stop4h 50m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 12/9

7:00 am-1:28 pm

1 stop6h 28m

Charlotte Douglas

Tue 12/16

6:44 pm-12:16 am

1 stop5h 32m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 12/20

5:52 pm-9:50 pm

1 stop3h 58m

Charlotte Douglas

Sat 12/27

5:05 pm-11:28 pm

1 stop6h 23m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 10/28

7:30 pm-11:58 pm

1 stop4h 28m

Charlotte Douglas

Tue 11/4

6:40 am-2:20 pm

2 stops7h 40m

$280

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 10/29

2:35 pm-6:51 pm

1 stop4h 16m

Charlotte Douglas

Thu 11/6

12:56 pm-6:50 pm

1 stop5h 54m

$286

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/29

Showing 1-10 of 20 results
1
2

Best time to book a flight from Buffalo to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Spartanburg

How far ahead should I book a flight from Buffalo to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Spartanburg. Price data was last updated on September 26, 2025.

The best time to book flights from Buffalo to Spartanburg is 77 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Spartanburg (average of $248). Flying from Buffalo to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SB1?

Find hourly flight availability from Buffalo to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 1, 2025.

When flying from Buffalo to Spartanburg, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Buffalo to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Buffalo to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Buffalo to Spartanburg flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated October 1, 2025.
Read through reviews of airlines operating flights from Buffalo to Spartanburg, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,961 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,030 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,154 reviews
Southwest
8.0
Very good
4,248 reviews

Boarding

8.1

Comfort

8.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Spartanburg?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to Spartanburg. You should not have trouble finding flights to Spartanburg from Buffalo; the airport handles an average of 1 outbound flight to Spartanburg per day. You should also have plenty of airline options to choose from since 5 airlines have flights from the Buffalo airport to Spartanburg. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How popular is this Buffalo to Spartanburg flight route?

    This flight path from Buffalo to Spartanburg was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Buffalo to Spartanburg?

    Departing from Buffalo to Spartanburg will take you 2h 03m. The distance between Buffalo and Spartanburg is about 546 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Buffalo to Spartanburg?

    The cheapest flight price from Buffalo to Spartanburg is $99. On average you can expect to pay $475. The most popular route, (Buffalo - Charlotte Douglas), can usually be booked for $210.

  • Can I find deals for flights from Buffalo to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Buffalo to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Spartanburg.

  • Can I find deals for business class flights from Buffalo to Spartanburg?

    Yes. Cheapflights offers flight deals from Buffalo to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Spartanburg (average of $248). Flying from Buffalo to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Spartanburg

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Buffalo to Spartanburg

Discover the top 5 airlines that operate flights from Buffalo to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$63Average$185FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$177Average$319FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$189Average$376FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$195Average$379FlexibilityNo cancel feeOn-time69%
DeltaCheapest$195Average$304FlexibilityNo cancel feeOn-timeN/A

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