$84+ Cheap flights from Buffalo (BUF) to Spartanburg, SC
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CLT
Mar 23 — Mar 301
1 adult, Economy
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Find cheap flights from Buffalo to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Buffalo to Spartanburg are usually found in August or May, booked 69 days in advance, depart on a Wednesday or Tuesday and return on a Saturday
Cheap flight deals from Buffalo to Spartanburg
Cheapest
Best
Last-minute
One-way
Cheapest flights from Buffalo to SpartanburgExplore the most affordable flight options available from Buffalo to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
Explore the most affordable flight options available from Buffalo to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2026.
This Frontier deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:52 am
BUF
- CLT
1 stop5h 38m
Frontier
Sun 4/1910:07 am
CLT
- BUF
1 stop9h 06m
Frontier
Deal found 2/21![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:25 pm
BUF
- CLT
1 stop10h 38m
Frontier
Thu 3/128:56 am
CLT
- BUF
2 stops27h 09m
Frontier
Deal found 2/20![Frontier logo]()
$185
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:25 am
BUF
- CLT
1 stop23h 05m
Frontier
Thu 5/145:41 pm
CLT
- BUF
1 stop15h 06m
Frontier
Deal found 2/18![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:25 pm
BUF
- CLT
1 stop10h 33m
Frontier
Sat 3/148:56 am
CLT
- BUF
2 stops26h 54m
Frontier
Deal found 2/19![Frontier logo]()
$195
This Frontier deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2411:02 am
BUF
- CLT
1 stop5h 28m
Frontier
Mon 4/2710:22 am
CLT
- BUF
1 stop9h 04m
Frontier
Deal found 2/19![Frontier logo]()
$202
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
BUF
- CLT
1 stop9h 10m
Southwest
Tue 3/108:10 am
CLT
- BUF
1 stop3h 30m
Southwest
Deal found 2/17![Southwest logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:08 pm
BUF
- CLT
2 stops30h 02m
Multiple Airlines
Thu 5/146:30 am
CLT
- BUF
1 stop12h 43m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$210
This CheapOair deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:37 pm
BUF
- CLT
1 stop16h 06m
Frontier
Mon 3/29:46 am
CLT
- BUF
1 stop6h 04m
Frontier
Deal found 2/21![Frontier logo]()
$213
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:50 pm
BUF
- CLT
1 stop4h 15m
Southwest
Mon 3/238:00 pm
CLT
- BUF
1 stop4h 10m
Southwest
Deal found 2/18![Southwest logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2212:45 pm
BUF
- CLT
2 stops43h 18m
Frontier
Sun 3/298:13 pm
CLT
- BUF
1 stop14h 36m
Frontier
Deal found 2/20![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:25 pm
BUF
- CLT
1 stop10h 38m
Frontier
Wed 3/181:59 pm
CLT
- BUF
2 stops22h 06m
Frontier
Deal found 2/18![Frontier logo]()
$222
Best flights from Buffalo to SpartanburgDiscover carefully curated flight deals from Buffalo to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
Discover carefully curated flight deals from Buffalo to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 21, 2026.
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
BUF
- CLT
1 stop9h 10m
Southwest
Tue 3/108:10 am
CLT
- BUF
1 stop3h 30m
Southwest
Deal found 2/17![Southwest logo]()
$206
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/241:32 pm
BUF
- CLT
Nonstop2h 02m
American Airlines
Sat 3/285:23 pm
CLT
- BUF
Nonstop1h 48m
American Airlines
Deal found 2/17![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 pm
BUF
- CLT
1 stop4h 15m
Southwest
Mon 4/277:20 pm
CLT
- BUF
1 stop4h 00m
Southwest
Deal found 2/18![Southwest logo]()
$274
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:55 am
BUF
- CLT
Nonstop2h 06m
American Airlines
Tue 3/244:04 pm
CLT
- BUF
Nonstop1h 50m
American Airlines
Deal found 2/17![American Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/174:15 pm
BUF
- CLT
1 stop5h 50m
Southwest
Tue 3/2410:55 am
CLT
- BUF
1 stop7h 25m
Southwest
Deal found 2/17![Southwest logo]()
$291
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:30 am
BUF
- CLT
1 stop5h 04m
American Airlines
Mon 3/2310:06 pm
CLT
- BUF
Nonstop1h 44m
American Airlines
Deal found 2/17![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:25 am
BUF
- CLT
1 stop10h 25m
Southwest
Sun 4/197:00 am
CLT
- BUF
1 stop8h 25m
Southwest
Deal found 2/17![Southwest logo]()
$294
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/263:55 pm
BUF
- CLT
1 stop6h 00m
Southwest
Fri 4/38:00 pm
CLT
- BUF
1 stop4h 10m
Southwest
Deal found 2/17![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:25 pm
BUF
- CLT
1 stop6h 45m
Southwest
Sat 3/1412:55 pm
CLT
- BUF
1 stop4h 20m
Southwest
Deal found 2/19![Southwest logo]()
$300
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2112:25 pm
BUF
- CLT
2 stops10h 25m
Southwest
Mon 3/238:00 pm
CLT
- BUF
1 stop4h 10m
Southwest
Deal found 2/18![Southwest logo]()
$302
Last-minute flights from Buffalo to SpartanburgDiscover last-minute flight deals from Buffalo to Spartanburg. Data last updated February 21, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Spartanburg. Data last updated February 21, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/284:37 pm
BUF
- CLT
1 stop16h 06m
Frontier
Mon 3/210:42 pm
CLT
- BUF
1 stop19h 39m
Frontier
Deal found 2/19![Frontier logo]()
$213
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:00 am
BUF
- CLT
1 stop9h 10m
Southwest
Tue 3/108:10 am
CLT
- BUF
1 stop3h 30m
Southwest
Deal found 2/17![Southwest logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:25 pm
BUF
- CLT
1 stop10h 33m
Frontier
Sat 3/148:56 am
CLT
- BUF
2 stops26h 54m
Frontier
Deal found 2/19![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:25 pm
BUF
- CLT
1 stop10h 38m
Frontier
Thu 3/128:56 am
CLT
- BUF
2 stops27h 09m
Frontier
Deal found 2/20![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:25 pm
BUF
- CLT
1 stop10h 38m
Frontier
Wed 3/181:59 pm
CLT
- BUF
2 stops22h 06m
Frontier
Deal found 2/18![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:50 pm
BUF
- CLT
2 stops35h 03m
Multiple Airlines
Fri 3/2711:12 am
CLT
- BUF
1 stop9h 18m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$230
This Orbitz deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/209:25 pm
BUF
- CLT
1 stop16h 25m
Frontier
Fri 3/279:28 pm
CLT
- BUF
1 stop23h 02m
Frontier
Deal found 2/18![Frontier logo]()
$234
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:50 pm
BUF
- CLT
1 stop4h 15m
Southwest
Mon 3/238:00 pm
CLT
- BUF
1 stop4h 10m
Southwest
Deal found 2/18![Southwest logo]()
$217
This Southwest deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:50 pm
BUF
- CLT
1 stop4h 15m
Southwest
Fri 3/278:00 pm
CLT
- BUF
1 stop4h 10m
Southwest
Deal found 2/17![Southwest logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2212:45 pm
BUF
- CLT
2 stops43h 18m
Frontier
Sun 3/298:13 pm
CLT
- BUF
1 stop14h 36m
Frontier
Deal found 2/20![Frontier logo]()
$221
One-way flights from Buffalo to SpartanburgSearch for one-way flight options from Buffalo to Spartanburg. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
Search for one-way flight options from Buffalo to Spartanburg. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:25 am
BUF
- CLT
1 stop10h 25m
Southwest
Deal found 2/18![Southwest logo]()
$84
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:59 pm
BUF
- CLT
1 stop27h 37m
Frontier
Deal found 2/20![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:56 pm
BUF
- CLT
2 stops29h 18m
Frontier
Deal found 2/18![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:19 am
BUF
- CLT
1 stop29h 16m
Frontier
Deal found 2/20![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:52 am
BUF
- CLT
1 stop5h 38m
Frontier
Deal found 2/20![Frontier logo]()
$101
This Super.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/112:04 pm
BUF
- CLT
1 stop20h 47m
Frontier
Deal found 2/19![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1912:07 pm
BUF
- CLT
2 stops22h 10m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2012:50 pm
BUF
- CLT
2 stops35h 03m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:59 am
BUF
- CLT
2 stops20h 04m
Frontier
Deal found 2/20![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1912:50 pm
BUF
- CLT
2 stops20h 26m
Frontier
Deal found 2/17![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/51:39 pm
BUF
- CLT
2 stops27h 26m
Frontier
Deal found 2/18![Frontier logo]()
$113
Find flight deals from Buffalo to Spartanburg
Keep the following information in mind while searching for Buffalo to Spartanburg flight deals. Data was last updated February 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Frontier) |
One-way from | $84 (Southwest) |
Popular in | December |
Cheapest in | August |
Average price | $315 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Buffalo to Spartanburg that are best for you.
Fly from
Buffalo
Fly to
Spartanburg
Route
Depart
Return
Price
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Sat 3/7
6:00 am-3:10 pm
1 stop9h 10m
Charlotte Douglas
Tue 3/10
8:10 am-11:40 am
1 stop3h 30m
$206
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Tue 3/24
1:32 pm-3:34 pm
Nonstop2h 02m
Charlotte Douglas
Sat 3/28
5:23 pm-7:11 pm
Nonstop1h 48m
$261
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Fri 4/24
5:20 pm-9:35 pm
1 stop4h 15m
Charlotte Douglas
Mon 4/27
7:20 pm-11:20 pm
1 stop4h 00m
$274
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Tue 3/17
4:15 pm-10:05 pm
1 stop5h 50m
Charlotte Douglas
Tue 3/24
10:55 am-6:20 pm
1 stop7h 25m
$291
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Tue 3/17
8:55 am-11:01 am
Nonstop2h 06m
Charlotte Douglas
Tue 3/24
4:04 pm-5:54 pm
Nonstop1h 50m
$293
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Fri 4/17
11:25 am-9:50 pm
1 stop10h 25m
Charlotte Douglas
Sun 4/19
7:00 am-3:25 pm
1 stop8h 25m
$294
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Thu 3/26
3:55 pm-9:55 pm
1 stop6h 00m
Charlotte Douglas
Fri 4/3
8:00 pm-12:10 am
1 stop4h 10m
$297
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Sat 3/21
5:30 am-10:34 am
1 stop5h 04m
Charlotte Douglas
Mon 3/23
10:06 pm-11:50 pm
Nonstop1h 44m
$299
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Sun 3/8
12:25 pm-7:10 pm
1 stop6h 45m
Charlotte Douglas
Sat 3/14
12:55 pm-5:15 pm
1 stop4h 20m
$300
BuffaloCharlotte
BUF - CLT
BUFCLT
Buffalo
Sat 3/21
12:25 pm-10:50 pm
2 stops10h 25m
Charlotte Douglas
Mon 3/23
8:00 pm-12:10 am
1 stop4h 10m
$302
Showing 1-10 of 21 results
Best time to book a flight from Buffalo to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Buffalo with our price prediction graph.
BUF-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Spartanburg
BUF-SB1
BUF-CLT
How far ahead should I book a flight from Buffalo to Spartanburg?
Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Spartanburg. Price data was last updated on February 20, 2026.
The best time to book flights from Buffalo to Spartanburg is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Buffalo to Spartanburg?
Currently, July is the cheapest month in which you can book a flight from Buffalo to Spartanburg (average of $53). Flying from Buffalo to Spartanburg in June is currently the most expensive (average of $118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from BUF to SB1?
Find hourly flight availability from Buffalo to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2026.
A simple way to save on the total cost of your ticket is to fly from Buffalo to Spartanburg in the evening. If you’re flexible enough to do this you can expect to save up to 30% on your trip compared to booking a flight in the morning.
What is the cheapest day to fly from Buffalo to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from Buffalo to Spartanburg. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Buffalo to Spartanburg flight should consider departing on Sunday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Buffalo to Spartanburg
Explore weekly flight availability from Buffalo to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 21, 2026.
The most flights from BUF to SB1 are scheduled on a Saturday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated February 21, 2026.
Read through reviews of airlines operating flights from Buffalo to Spartanburg, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Entertainment
7.5
Crew
8.6
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Buffalo and Spartanburg flights
Browse other Buffalo and Spartanburg flight options. Last updated on February 21, 2026.
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Top 5 airlines flying from Buffalo to Spartanburg
Discover the top 5 airlines that operate flights from Buffalo to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$131 | Average$310 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$159 | Average$228 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$174 | Average$382 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$189 | Average$354 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$207 | Average$323 | FlexibilityNo cancel fee | On-time71% |