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$64+ Cheap flights from Buffalo (BUF) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CLT
Dec 16 — Dec 231
Tue 12/16
Tue 12/23
1 adult, Economy
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Cheapflights Tip: The best prices from Buffalo to Spartanburg are usually found in January or April, booked 90 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Buffalo to Spartanburg

Keep the following information in mind while searching for Buffalo to Spartanburg flight deals. Data was last updated November 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$180
(Frontier)

One-way from

$64
(Trip.com)

Popular in

October

Cheapest in

January

Average price

$296
Provider with most accurate pricing for Buffalo-Charlotte Douglas flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Charlotte Douglas flights.
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From Buffalo to Spartanburg
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One-way flight from Buffalo to Spartanburg
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Highest demand for flights based on searches. 8% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Buffalo to Spartanburg

Cheapest flights from Buffalo to Spartanburg
Explore the most affordable flight options available from Buffalo to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:37 pmBUF - CLT
1 stop7h 23mMultiple Airlines
Wed 1/79:34 pmCLT - BUF
1 stop10h 39mMultiple Airlines
Deal found 11/16$195
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:18 pmBUF - CLT
1 stop18h 19mFrontier
Sun 12/219:33 pmCLT - BUF
1 stop23h 35mFrontier
Deal found 11/16$200
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:05 pmBUF - CLT
2 stops21h 34mMultiple Airlines
Sun 12/219:33 pmCLT - BUF
1 stop23h 35mMultiple Airlines
Deal found 11/16$232
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amBUF - CLT
Nonstop2h 09mAmerican Airlines
Sat 12/2710:35 pmCLT - BUF
Nonstop1h 37mAmerican Airlines
Deal found 11/15$253
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/209:28 amBUF - CLT
1 stop10h 41mMultiple Airlines
Tue 12/239:34 pmCLT - BUF
1 stop23h 06mMultiple Airlines
Deal found 11/15$255
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:05 amBUF - CLT
Nonstop2h 03mAmerican Airlines
Tue 12/29:41 pmCLT - BUF
Nonstop1h 45mAmerican Airlines
Deal found 11/16$261
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:35 pmBUF - CLT
Nonstop2h 05mAmerican Airlines
Wed 1/75:30 pmCLT - BUF
1 stop5h 10mAmerican Airlines
Deal found 11/16$263
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:00 amBUF - CLT
1 stop5h 32mAmerican Airlines
Sat 11/2910:30 pmCLT - BUF
Nonstop1h 49mAmerican Airlines
Deal found 11/15$271
This American Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:15 pmBUF - CLT
Nonstop2h 09mAmerican Airlines
Wed 12/314:48 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Deal found 11/16$273
This American Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:57 pmBUF - CLT
Nonstop1h 58mAmerican Airlines
Mon 12/154:07 pmCLT - BUF
Nonstop1h 43mAmerican Airlines
Deal found 11/15$277
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:05 pmBUF - CLT
2 stops16h 45mFrontier
Fri 12/510:33 pmCLT - BUF
1 stop15h 42mFrontier
Deal found 11/16$280

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
Use the filters below to find and compare flights from Buffalo to Spartanburg that are best for you.

Fly from

Buffalo

Fly to

Spartanburg

Route

Depart

Return

Price

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 12/12

12:37 pm-3:27 pm

2 stops26h 50m

Charlotte Douglas

Wed 1/7

9:34 pm-8:13 am

1 stop10h 39m

$235

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 12/20

7:15 pm-9:24 pm

Nonstop2h 09m

Charlotte Douglas

Sat 12/27

10:35 pm-12:12 am

Nonstop1h 37m

$253

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 1/6

11:50 am-6:49 pm

1 stop6h 59m

Charlotte Douglas

Tue 3/3

4:05 pm-5:53 pm

Nonstop1h 48m

$263

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 1/7

6:00 am-12:23 pm

1 stop6h 23m

Charlotte Douglas

Tue 3/3

6:53 pm-12:16 am

1 stop5h 23m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Wed 12/17

3:40 pm-7:55 pm

1 stop4h 15m

Charlotte Douglas

Wed 1/7

11:05 am-3:10 pm

1 stop4h 05m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 1/6

12:07 pm-4:07 pm

1 stop4h 00m

Charlotte Douglas

Sat 2/28

2:00 pm-8:21 pm

1 stop6h 21m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Sat 2/28

7:00 am-1:30 pm

1 stop6h 30m

Charlotte Douglas

Tue 3/3

7:00 am-2:10 pm

1 stop7h 10m

$273

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Tue 1/6

5:50 am-10:20 am

1 stop4h 30m

Charlotte Douglas

Tue 3/3

7:45 am-4:15 pm

2 stops8h 30m

$278

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 12/12

6:35 pm-8:40 pm

Nonstop2h 05m

Charlotte Douglas

Wed 1/7

9:55 pm-11:41 pm

Nonstop1h 46m

$280

BuffaloCharlotte

BUF - CLT

BUFCLT

Buffalo

Fri 1/9

5:44 pm-9:34 pm

1 stop3h 50m

Charlotte Douglas

Wed 3/4

10:31 am-2:58 pm

1 stop4h 27m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 22 results
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Best time to book a flight from Buffalo to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Spartanburg

How far ahead should I book a flight from Buffalo to Spartanburg?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to Spartanburg. Price data was last updated on November 14, 2025.

The best time to book flights from Buffalo to Spartanburg is 90 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to Spartanburg?

Currently, July is the cheapest month in which you can book a flight from Buffalo to Spartanburg (average of $53). Flying from Buffalo to Spartanburg in February is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SB1?

Find hourly flight availability from Buffalo to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 16, 2025.

A simple way to save on the total cost of your ticket is to fly from Buffalo to Spartanburg in the afternoon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Buffalo to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Buffalo to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Buffalo to Spartanburg flight should consider departing on Sunday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Buffalo to Spartanburg

Explore weekly flight availability from Buffalo to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 16, 2025.

The most flights from BUF to SB1 are scheduled on a Friday (3 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated November 16, 2025.
Read through reviews of airlines operating flights from Buffalo to Spartanburg, such as Southwest, Delta, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
8,007 reviews
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,013 reviews
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,050 reviews
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,106 reviews
Southwest
8.0
Very good
4,244 reviews

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Spartanburg?

    Buffalo (BUF) is the airport you will fly out of if you book a flight from Buffalo to Spartanburg. You should not have trouble finding flights to Spartanburg from Buffalo; the airport handles an average of 2 outbound flights to Spartanburg per day. You should also have plenty of airline options to choose from since 5 airlines have flights from the Buffalo airport to Spartanburg. It is only a 8.3 mi journey to Buffalo (BUF) from Buffalo’s city center.

  • How popular is this Buffalo to Spartanburg flight route?

    This flight path from Buffalo to Spartanburg was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Buffalo to Spartanburg?

    Departing from Buffalo to Spartanburg will take you 2h 09m. The distance between Buffalo and Spartanburg is about 546 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Buffalo to Spartanburg?

    The cheapest flight price from Buffalo to Spartanburg is $96. On average you can expect to pay $662. The most popular route, (Buffalo - Charlotte Douglas), can usually be booked for $245.

  • Can I find deals for flights from Buffalo to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Buffalo to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Spartanburg.

  • Can I find deals for business class flights from Buffalo to Spartanburg?

    Yes. Cheapflights offers flight deals from Buffalo to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Spartanburg?

    Currently, July is the cheapest month in which you can book a flight from Buffalo to Spartanburg (average of $53). Flying from Buffalo to Spartanburg in February is currently the most expensive (average of $123). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Buffalo to Spartanburg

Discover the top 5 airlines that operate flights from Buffalo to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$63Average$190FlexibilityNo cancel feeOn-time62%
DeltaCheapest$131Average$303FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$177Average$324FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$189Average$386FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$252Average$410FlexibilityNo cancel feeOn-time69%

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