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$245+ Cheap flights from Key Largo, FL to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — MAD
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Key Largo to Spain

Cheapest flights from Key Largo to Spain
Explore the most affordable flight options available from Key Largo to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:15 pmMIA - MAD
1 stop18h 44mITA Airways
Thu 1/2911:40 amMAD - MIA
1 stop15h 15mITA Airways
Deal found 12/15$454
This Mytrip deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:15 pmMIA - MAD
1 stop18h 44mITA Airways
Wed 1/146:00 pmMAD - MIA
1 stop32h 55mITA Airways
Deal found 12/15$466
This eDestinos deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:30 pmMIA - MAD
Nonstop8h 35mIberia
Tue 1/274:25 pmMAD - MIA
Nonstop10h 20mIberia
Deal found 12/15$470
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:30 pmMIA - MAD
Nonstop8h 35mFinnair
Wed 1/2812:55 amMAD - MIA
1 stop25h 44mFinnair
Deal found 12/15$472
This British Airways deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:20 pmMIA - MAD
Nonstop8h 35mBritish Airways
Thu 1/2911:30 amMAD - MIA
Nonstop10h 15mBritish Airways
Deal found 12/13$474
This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:30 pmMIA - MAD
Nonstop8h 35mFinnair
Wed 1/147:05 amMAD - MIA
1 stop14h 20mFinnair
Deal found 12/15$477
This Finnair deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:06 pmMIA - MAD
1 stop11h 49mMultiple Airlines
Thu 1/2910:00 amMAD - MIA
Nonstop9h 55mMultiple Airlines
Deal found 12/14$478
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:15 amMIA - MAD
1 stop20h 00mUnited Airlines
Wed 12/1711:15 amMAD - MIA
1 stop14h 59mUnited Airlines
Deal found 12/13$480
This Cheapflightsfares deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:20 pmMIA - MAD
Nonstop8h 35mFinnair
Mon 1/129:35 pmMAD - MIA
1 stop23h 50mFinnair
Deal found 12/13$482
This oojo deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:15 pmMIA - MAD
1 stop18h 44mITA Airways
Wed 1/216:00 pmMAD - MIA
1 stop32h 55mITA Airways
Deal found 12/13$484
This KLM deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/264:50 pmMIA - MAD
1 stop14h 50mKLM
Tue 1/206:00 amMAD - MIA
1 stop14h 50mKLM
Deal found 12/14$487
This Finnair deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:30 pmMIA - VLC
1 stop19h 35mFinnair
Tue 2/37:30 amVLC - MIA
1 stop13h 55mFinnair
Deal found 12/13$488

Find flight deals from Key Largo to Spain

Keep the following information in mind while searching for Key Largo to Spain flight deals. Data was last updated December 15, 2025.

Round-trip from

$435
(Trip.com)

One-way from

$245
(Kiwi.com)

Popular in

June

Cheapest in

February

Average price

$811
From Key Largo to Spain
Search Deals
One-way flight from Key Largo to Spain
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($225 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Key Largo to Spain that are best for you.

Fly from

Key Largo

Fly to

Spain

Route

Depart

Return

Price

MiamiSeville

MIA - SVQ

MIASVQ

Miami

Fri 2/6

7:55 pm-5:25 pm

1 stop15h 30m

Sevilla

Sat 2/21

7:15 pm-6:35 pm

1 stop29h 20m

$456

MiamiPalma de Mallorca

MIA - PMI

MIAPMI

Miami

Fri 1/16

8:40 pm-11:10 am

1 stop32h 30m

Palma de Mallorca Son Sant Joan

Sun 2/1

12:00 pm-6:35 pm

1 stop36h 35m

$463

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Tue 3/3

8:45 am-8:00 am

2 stops17h 15m

Madrid Barajas

Mon 3/16

12:40 pm-1:15 pm

2 stops29h 35m

$472

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Tue 1/13

9:00 am-4:40 pm

2 stops25h 40m

Madrid Barajas

Tue 2/3

1:35 pm-10:20 pm

2 stops38h 45m

$478

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 1/12

1:45 pm-4:40 pm

2 stops20h 55m

Madrid Barajas

Mon 1/19

1:35 pm-10:20 pm

3 stops38h 45m

$478

MiamiMadrid

MIA - MAD

MIAMAD

Miami

Mon 1/12

7:40 am-9:10 am

2 stops19h 30m

Madrid Barajas

Wed 1/21

1:05 pm-2:50 pm

1 stop31h 45m

$485

MiamiIbiza

MIA - IBZ

MIAIBZ

Miami

Tue 1/27

3:35 pm-12:50 pm

1 stop15h 15m

Ibiza

Tue 2/3

11:05 am-8:45 pm

2 stops15h 40m

$486

MiamiPalma de Mallorca

MIA - PMI

MIAPMI

Miami

Wed 1/28

9:45 pm-6:25 pm

1 stop14h 40m

Palma de Mallorca Son Sant Joan

Wed 2/4

12:25 pm-7:30 pm

1 stop13h 05m

$486

MiamiIbiza

MIA - IBZ

MIAIBZ

Miami

Thu 1/22

10:30 pm-5:00 pm

1 stop12h 30m

Ibiza

Wed 2/4

9:40 pm-1:55 pm

1 stop22h 15m

$487

MiamiValencia

MIA - VLC

MIAVLC

Miami

Mon 1/19

9:05 pm-9:10 am

2 stops54h 05m

Valencia

Fri 1/23

12:45 pm-10:40 am

2 stops27h 55m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
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Best time to book a flight from Key Largo to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Spain

What is the cheapest month to book a flight from Key Largo to Spain?

Currently, October is the cheapest month in which you can book a flight from Key Largo to Spain (average of $111). Flying from Key Largo to Spain in June is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to ES?

Find hourly flight availability from Key Largo to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Key Largo to Spain, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 9% versus a flight in the afternoon.

What is the cheapest day to fly from Key Largo to Spain?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to Spain. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to Spain flight should consider departing on Monday mornings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to Spain

Explore weekly flight availability from Key Largo to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 15, 2025.

The most flights from KE9 to ES0 are scheduled on a Tuesday (24 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (15 on average).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated December 15, 2025.
Peruse reviews from past customers who have flown with American Airlines, TAP AIR PORTUGAL, and Air Europa from Key Largo to Spain to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,048 reviews
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
TAP AIR PORTUGAL
7.2
Good
2,089 reviews
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Air Europa
7.0
Good
571 reviews
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Iberia
7.0
Good
3,052 reviews
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
British Airways
6.7
Okay
7,579 reviews
American Airlines
7.2
Good
11,048 reviews

Crew

8.0

Overall

7.2

Comfort

7.2

Entertainment

6.9

Food

6.5

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to Spain flight route?

    Flights from Key Largo to Spain have been viewed 307 times in the past calendar month.

  • How long is the flight from Key Largo to Spain?

    There are many flights that can get you from Key Largo to Spain in 15h 30m. Fly via Scandinavian Airlines, United Airlines, or Delta to get the fastest option. The distance from Key Largo to Spain is about 4337 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to Spain one-way?

    $164 is the cheapest one-way deal found within the past few days, from TAP AIR PORTUGAL. You may also be able to find cheap deals on LEVEL and LEVEL, with prices starting from $202 and $204, respectively.

  • What are the most popular routes from Key Largo to Spain?

    When deciding which route to take from Key Largo to Spain consider Miami - Madrid Barajas, Miami - Barcelona-El Prat or Miami - Malaga as they are the most popular.

  • What are the most reliable airlines from Key Largo to Spain?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Spain on time: Kuwait Airways (100%), Royal Jordanian (93%), Finnair (87%).

  • What are the cheapest flights from Key Largo to Spain?

    On average you can expect to pay $1,633 for a flight from Key Largo to Spain. The cheapest flight overall is $339 while the most popular route, (Miami - Madrid Barajas) is currently priced at $380.

  • Can I find deals for flights from Key Largo to Spain that include hotel bookings?

    Yes. In addition to deals on Key Largo to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Spain.

  • Can I find deals for business class flights from Key Largo to Spain?

    Yes. Cheapflights offers flight deals from Key Largo to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Spain?

    Currently, October is the cheapest month in which you can book a flight from Key Largo to Spain (average of $111). Flying from Key Largo to Spain in June is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 10 airlines flying from Key Largo to Spain

Discover the top 10 airlines that operate flights from Key Largo to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$111Average$574FlexibilityNo cancel feeOn-time62%
SWISSCheapest$137Average$698FlexibilityNo cancel feeOn-time79%
ITA AirwaysCheapest$277Average$663FlexibilityNo cancel feeOn-time81%
LEVELCheapest$342Average$622FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$351Average$683FlexibilityNo cancel feeOn-time69%
DeltaCheapest$367Average$706FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$378Average$676FlexibilityNo cancel feeOn-time67%
KLMCheapest$383Average$619FlexibilityNo cancel feeOn-time75%
Scandinavian AirlinesCheapest$385Average$721FlexibilityNo cancel feeOn-time77%
VuelingCheapest$389Average$678FlexibilityNo cancel feeOn-time88%

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