HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Spain

$199+ Cheap flights from Key Largo, FL to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — MAD
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Key Largo to Spain with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Key Largo to Spain

Keep the following information in mind while searching for Key Largo to Spain flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$402
(TAP AIR PORTUGAL)

One-way from

$199
(SmartFares)

Popular in

June

Cheapest in

February

Average price

$677
From Key Largo to Spain
Search Deals
One-way flight from Key Largo to Spain
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($230 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Key Largo to Spain

Cheapest flights from Key Largo to Spain
Explore the most affordable flight options available from Key Largo to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This TAP AIR PORTUGAL deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TAP AIR PORTUGAL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3112:35 amMIA - MAD
1 stop14h 45mTAP AIR PORTUGAL
mié. 11/122:55 pmMAD - MIA
1 stop12h 55mTAP AIR PORTUGAL
Deal found 9/13$402
This eDestinos deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/89:45 pmMIA - MAD
1 stop12h 30mIberia
mar. 11/410:00 amMAD - MIA
Nonstop9h 55mIberia
Deal found 9/12$403
This lol.travel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/1712:25 amMIA - BIO
1 stop11h 10mTAP AIR PORTUGAL
lun. 11/37:20 pmBIO - MIA
1 stop25h 30mTAP AIR PORTUGAL
Deal found 9/14$404
This lol.travel deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/204:35 pmMIA - TFS
1 stop14h 40mTAP AIR PORTUGAL
lun. 11/32:25 pmTFS - MIA
1 stop29h 25mTAP AIR PORTUGAL
Deal found 9/14$404
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/275:35 pmMIA - MAD
1 stop18h 35mTAP AIR PORTUGAL
mar. 11/116:00 pmMAD - MIA
1 stop26h 50mTAP AIR PORTUGAL
Deal found 9/13$404
This Booking.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/2710:45 pmMIA - MAD
Nonstop8h 20mAir Europa
mar. 11/113:25 pmMAD - MIA
Nonstop10h 05mAir Europa
Deal found 9/13$405
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1211:35 pmMIA - MAD
1 stop17h 55mTAP AIR PORTUGAL
sáb. 11/229:10 pmMAD - MIA
1 stop23h 40mTAP AIR PORTUGAL
Deal found 9/14$407
This eDestinos deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/239:55 pmMIA - MAD
Nonstop8h 50mIberia
sáb. 11/811:30 amMAD - MIA
Nonstop10h 15mIberia
Deal found 9/14$408
This oojo deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/1611:50 pmMIA - BIO
1 stop12h 45mTAP AIR PORTUGAL
dom. 11/236:40 pmBIO - MIA
1 stop26h 10mTAP AIR PORTUGAL
Deal found 9/13$409
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/44:35 pmMIA - MAD
1 stop10h 55mTAP AIR PORTUGAL
mié. 11/1210:20 amMAD - MIA
1 stop17h 30mTAP AIR PORTUGAL
Deal found 9/12$409
This oojo deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/174:35 pmMIA - LPA
1 stop15h 45mTAP AIR PORTUGAL
mar. 11/252:15 pmLPA - MIA
1 stop29h 35mTAP AIR PORTUGAL
Deal found 9/13$409
This lol.travel deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/254:30 pmMIA - SVQ
1 stop17h 50mTAP AIR PORTUGAL
vie. 11/76:30 amSVQ - MIA
1 stop20h 50mTAP AIR PORTUGAL
Deal found 9/13$410

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Key Largo to Spain that are best for you.

Fly from

Key Largo

Fly to

Spain

Route

Depart

Return

Price

MiamiBilbao

MIA - BIO

MIABIO

Miami

vie. 10/17

12:25 am-5:35 pm

1 stop11h 10m

Bilbao

lun. 11/3

7:20 pm-2:50 pm

1 stop25h 30m

$404

MiamiGranadilla

MIA - TFS

MIATFS

Miami

lun. 10/20

4:35 pm-12:15 pm

1 stop14h 40m

Granadilla Tenerife-Sur

lun. 11/3

2:25 pm-2:50 pm

1 stop29h 25m

$404

MiamiBilbao

MIA - BIO

MIABIO

Miami

dom. 11/30

11:50 pm-6:35 pm

1 stop12h 45m

Bilbao

mié. 12/10

12:10 pm-9:50 pm

1 stop15h 40m

$409

MiamiSeville

MIA - SVQ

MIASVQ

Miami

sáb. 10/25

4:30 pm-4:20 pm

1 stop17h 50m

Sevilla

vie. 11/7

6:30 am-9:20 pm

1 stop20h 50m

$410

MiamiAlicante

MIA - ALC

MIAALC

Miami

lun. 11/3

7:55 pm-5:45 pm

1 stop15h 50m

Alicante

dom. 11/16

6:25 pm-6:05 pm

1 stop29h 40m

$418

MiamiMadrid

MIA - MAD

MIAMAD

Miami

dom. 11/23

7:00 am-4:10 pm

2 stops27h 10m

Madrid Barajas

mié. 12/3

5:00 pm-6:05 pm

2 stops31h 05m

$421

MiamiMadrid

MIA - MAD

MIAMAD

Miami

lun. 11/17

7:00 am-4:10 pm

2 stops27h 10m

Madrid Barajas

sáb. 11/22

6:35 pm-6:05 pm

1 stop29h 30m

$424

MiamiMadrid

MIA - MAD

MIAMAD

Miami

lun. 10/27

4:30 pm-5:50 am

Nonstop8h 20m

Madrid Barajas

mar. 11/11

4:25 pm-8:45 pm

Nonstop10h 20m

$425

MiamiValencia

MIA - VLC

MIAVLC

Miami

lun. 10/27

6:10 pm-4:10 pm

1 stop17h 00m

Valencia

mié. 11/12

7:30 am-3:00 pm

1 stop13h 30m

$429

MiamiAlicante

MIA - ALC

MIAALC

Miami

mié. 11/5

9:45 pm-5:45 pm

1 stop14h 00m

Alicante

mié. 11/19

10:40 am-8:00 pm

1 stop15h 20m

$434

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Key Largo to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to Spain

What is the cheapest month to book a flight from Key Largo to Spain?

Currently, November is the cheapest month in which you can book a flight from Key Largo to Spain (average of $543). Flying from Key Largo to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to ES?

Find hourly flight availability from Key Largo to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Key Largo to Spain, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Key Largo to Spain

Explore weekly flight availability from Key Largo to Spain. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 15, 2025.

The most flights from KE9 to ES0 are scheduled on a Tuesday (23 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (22 on average).

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated septiembre 15, 2025.
Peruse reviews from past customers who have flown with American Airlines, TAP AIR PORTUGAL, and Air Europa from Key Largo to Spain to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
TAP AIR PORTUGAL
7.1
Good
1,975 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Air Europa
7.0
Good
556 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Iberia
7.0
Good
2,924 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
British Airways
6.7
Okay
7,361 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to Spain flight route?

    Flights from Key Largo to Spain have been viewed 282 times in the past calendar month.

  • How long is the flight from Key Largo to Spain?

    There are many flights that can get you from Key Largo to Spain in 8h 20m. Fly via TAP AIR PORTUGAL, Scandinavian Airlines, or British Airways to get the fastest option. The distance from Key Largo to Spain is about 4412 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to Spain one-way?

    $217 is the cheapest one-way deal found within the past few days, from TAP AIR PORTUGAL. You may also be able to find cheap deals on Scandinavian Airlines and Iberia, with prices starting from $229 and $285, respectively.

  • What are the most popular routes from Key Largo to Spain?

    When deciding which route to take from Key Largo to Spain consider Miami - Madrid Barajas, Miami - Barcelona-El Prat or Miami - Las Palmas de Gran Canaria as they are the most popular.

  • What are the most reliable airlines from Key Largo to Spain?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Key Largo to Spain on time: Air Europa (92%), SAUDIA (92%), Kenya Airways (92%).

  • What are the cheapest flights from Key Largo to Spain?

    On average you can expect to pay $1,318 for a flight from Key Largo to Spain. The cheapest flight overall is $279 while the most popular route, (Miami - Madrid Barajas) is currently priced at $361.

  • Can I find deals for flights from Key Largo to Spain that include hotel bookings?

    Yes. In addition to deals on Key Largo to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to Spain.

  • Can I find deals for business class flights from Key Largo to Spain?

    Yes. Cheapflights offers flight deals from Key Largo to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to Spain?

    Currently, November is the cheapest month in which you can book a flight from Key Largo to Spain (average of $543). Flying from Key Largo to Spain in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Key Largo to Spain

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Madrid flights
Miami to Heathrow flights
Miami to Charles de Gaulle flights
Miami to Leonardo da Vinci/Fiumicino flights
Orlando to Heathrow flights
Miami to Barcelona-El Prat flights
Miami to Istanbul flights
Miami to Lisbon flights
Tampa to Heathrow flights
Orlando to Charles de Gaulle flights
Miami to Zurich flights
Miami to Gatwick flights
Miami to Frankfurt flights
Orlando to Gatwick flights
Fort Lauderdale to Madrid flights
Miami to Orly flights
Miami to London City flights
Orlando to Frankfurt flights
Orlando to Madrid flights
Orlando to Leonardo da Vinci/Fiumicino flights
Fort Lauderdale to Charles de Gaulle flights
Orlando to Orly flights
Miami to Stansted flights
Fort Lauderdale to Leonardo da Vinci/Fiumicino flights
Tampa to Frankfurt flights
Orlando to Dublin flights
Miami to Malpensa flights
Orlando to London City flights
Miami to Munich flights
Miami to Linate flights
Miami to Amsterdam flights
Fort Lauderdale to Heathrow flights
Miami to Sabiha Gokcen flights
Miami to Luton flights
Tampa to Gatwick flights
Miami to Athens flights
Orlando to Barcelona-El Prat flights
Orlando to Zurich flights
Miami to Beauvais-Tille flights
Fort Lauderdale to Barcelona-El Prat flights
Tampa to Leonardo da Vinci/Fiumicino flights
Orlando to Istanbul flights
Fort Lauderdale to Frankfurt flights
Orlando to Keflavik Intl flights
Tampa to London City flights
Tampa to Madrid flights
Orlando to Amsterdam flights
Tampa to Athens flights
Orlando to Munich flights
Miami to Basel flights

Top 10 airlines flying from Key Largo to Spain

Discover the top 10 airlines that operate flights from Key Largo to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$111Average$288FlexibilityNo cancel feeOn-time62%
SWISSCheapest$137Average$702FlexibilityNo cancel feeOn-time79%
Royal Air MarocCheapest$291Average$602FlexibilityNo cancel feeOn-time75%
AviancaCheapest$310Average$1,274FlexibilityNo cancel feeOn-time71%
ITA AirwaysCheapest$310Average$660FlexibilityNo cancel feeOn-time81%
LEVELCheapest$342Average$623FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$351Average$698FlexibilityNo cancel feeOn-time69%
KLMCheapest$364Average$639FlexibilityNo cancel feeOn-time75%
DeltaCheapest$367Average$708FlexibilityNo cancel feeOn-timeN/A
Air CanadaCheapest$378Average$654FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.