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$278+ Cheap flights from Des Moines (DSM) to Spain

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAD
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Des Moines to Spain

Keep the following information in mind while searching for Des Moines to Spain flight deals. Data was last updated November 20, 2025.

Round-trip from

$460
(Booking.com)

One-way from

$332
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$631
From Des Moines to Spain
Search Deals
One-way flight from Des Moines to Spain
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Highest demand for flights based on searches. 25% potential increase in price ($332 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($50 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Spain

Cheapest flights from Des Moines to Spain
Explore the most affordable flight options available from Des Moines to Spain. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This KLM deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:32 pmDSM - BCN
1 stop31h 08mMultiple Airlines
Wed 12/106:00 amBCN - DSM
2 stops17h 16mMultiple Airlines
Deal found 11/17$466
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/11:53 pmDSM - BCN
2 stops16h 47mAmerican Airlines
Wed 12/1012:30 pmBCN - DSM
2 stops18h 05mAmerican Airlines
Deal found 11/17$485
This Gurufare deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:50 pmDSM - BCN
2 stops15h 55mLufthansa
Wed 12/109:10 amBCN - DSM
2 stops19h 27mLufthansa
Deal found 11/18$521
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/12:17 pmDSM - BCN
1 stop11h 23mDelta
Wed 12/106:00 amBCN - DSM
2 stops18h 03mDelta
Deal found 11/18$586
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/249:01 amDSM - MAD
2 stops17h 14mUnited Airlines
Wed 12/35:55 amMAD - DSM
2 stops18h 29mUnited Airlines
Deal found 11/20$642
This KLM deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:35 amDSM - MAD
1 stop20h 40mKLM
Wed 12/36:00 amMAD - DSM
2 stops18h 47mKLM
Deal found 11/20$646
This Finnair deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:00 amDSM - MAD
1 stop20h 00mMultiple Airlines
Wed 12/31:00 pmMAD - DSM
1 stop17h 35mMultiple Airlines
Deal found 11/20$694
This KLM deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:59 pmDSM - SVQ
2 stops44h 16mKLM
Sun 12/79:05 pmSVQ - DSM
2 stops32h 29mKLM
Deal found 11/18$832
This Ovago deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:51 amDSM - BCN
2 stops18h 59mAer Lingus
Wed 12/1011:30 amBCN - DSM
2 stops17h 59mAer Lingus
Deal found 11/19$836
This Finnair deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1412:15 pmDSM - MAD
1 stop13h 35mMultiple Airlines
Sun 12/2112:00 pmMAD - DSM
1 stop13h 05mMultiple Airlines
Deal found 11/20$931
This Virgin Atlantic deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2311:28 amDSM - MAD
1 stop14h 47mVirgin Atlantic
Tue 11/2511:15 amMAD - DSM
1 stop18h 18mVirgin Atlantic
Deal found 11/19$995
This KLM deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:35 amDSM - MAD
1 stop20h 40mKLM
Tue 11/256:00 amMAD - DSM
2 stops17h 19mKLM
Deal found 11/19$998

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Spain that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Des Moines to Spain that are best for you.

Fly from

Des Moines

Fly to

Spain

Route

Depart

Return

Price

Des MoinesBarcelona

DSM - BCN

DSMBCN

Des Moines

Sat 1/10

6:48 pm-9:35 am

2 stops31h 47m

Barcelona-El Prat

Thu 1/22

1:35 pm-9:50 pm

2 stops39h 15m

$461

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 2/4

5:35 am-9:15 am

1 stop20h 40m

Madrid Barajas

Sun 2/8

6:00 am-9:24 pm

2 stops22h 24m

$466

Des MoinesBarcelona

DSM - BCN

DSMBCN

Des Moines

Sun 1/18

11:35 am-8:50 am

1 stop14h 15m

Barcelona-El Prat

Thu 1/29

10:40 am-11:23 pm

1 stop19h 43m

$474

Des MoinesBarcelona

DSM - BCN

DSMBCN

Des Moines

Thu 1/8

5:21 am-7:05 am

2 stops18h 44m

Barcelona-El Prat

Fri 1/16

11:00 am-11:23 pm

2 stops19h 23m

$475

Des MoinesBarcelona

DSM - BCN

DSMBCN

Des Moines

Thu 1/8

11:35 am-8:50 am

1 stop14h 15m

Barcelona-El Prat

Fri 1/23

3:05 pm-10:50 am

2 stops26h 45m

$476

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 1/14

5:21 am-9:25 am

1 stop21h 04m

Madrid Barajas

Wed 1/21

10:00 am-11:29 pm

1 stop20h 29m

$478

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 2/4

8:00 am-8:00 am

2 stops17h 00m

Madrid Barajas

Sun 2/8

5:55 am-9:50 pm

2 stops22h 55m

$487

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sat 1/24

5:21 am-9:25 am

1 stop21h 04m

Madrid Barajas

Fri 1/30

12:55 am-5:06 pm

1 stop23h 11m

$488

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 1/1

6:41 am-5:45 am

1 stop16h 04m

Madrid Barajas

Fri 1/30

12:55 am-3:15 pm

1 stop21h 20m

$488

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 2/12

6:00 am-7:55 am

1 stop18h 55m

Madrid Barajas

Mon 2/16

11:30 am-11:59 pm

1 stop19h 29m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 39 results
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Best time to book a flight from Des Moines to Spain

Have a flexible travel schedule? Discover the best time to fly to Spain from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Spain

What is the cheapest month to book a flight from Des Moines to Spain?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Spain (average of $485). Flying from Des Moines to Spain in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to ES?

Find hourly flight availability from Des Moines to Spain. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

When flying from Des Moines to Spain, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 11% versus a flight at noon.

Reviews of airlines servicing Spain

Get insights into the airlines that provide service to Spain. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spain. Reviews last updated November 20, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Des Moines to Spain to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,029 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Iberia
7.0
Good
3,027 reviews
Delta
7.9
Good
8,002 reviews

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Spain. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Spain?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Spain. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Spain?

    A quick flight from Des Moines to Spain can take about 18h 34m. United Airlines provides one of the quickest options available for as low as $626. The distance from Des Moines to Spain is about 4473 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Des Moines to Spain one-way?

    To fly one-way, consider booking your trip with Lufthansa, which is currently one of the cheapest options available, starting at $375. United Airlines flights start at $418 while deals on British Airways start at $538 one-way.

  • What are the most popular routes from Des Moines to Spain?

    The most popular route from Des Moines to Spain is Des Moines - Barcelona-El Prat. You may also consider Des Moines - Madrid Barajas or Des Moines - Sevilla.

  • Can I find deals for flights from Des Moines to Spain that include hotel bookings?

    Yes. In addition to deals on Des Moines to Spain flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Spain?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Spain.

  • Can I find deals for business class flights from Des Moines to Spain?

    Yes. Cheapflights offers flight deals from Des Moines to Spain by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Spain?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Spain (average of $485). Flying from Des Moines to Spain in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Spain

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Spain

Discover the top 4 airlines that operate flights from Des Moines to Spain. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$582Average$831FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$586Average$1,037FlexibilityNo cancel feeOn-time71%
DeltaCheapest$644Average$735FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$686Average$1,340FlexibilityNo cancel feeOn-time77%

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