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South Carolina

$54+ Cheap flights from Syracuse (SYR) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
SYR — CHS
Apr 15 — Apr 221
Wed 4/15
Wed 4/22
1 adult, Economy
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Cheap flight deals from Syracuse to South Carolina

Cheapest flights from Syracuse to South Carolina
Explore the most affordable flight options available from Syracuse to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 16, 2026.

This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:02 pm
SYR
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 6/86:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/16$116
This Gotogate deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:02 pm
SYR
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 6/226:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/16$118
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:02 pm
SYR
-
CHS
Nonstop2h 12m
Breeze Airways
Fri 9/116:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/13$127
This Booking.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:55 pm
SYR
-
CHS
Nonstop2h 19m
Breeze Airways
Fri 4/176:05 am
CHS
-
SYR
Nonstop2h 08m
Breeze Airways
Deal found 3/14$129
This Booking.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:02 pm
SYR
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 5/116:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/16$146
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:02 pm
SYR
-
CHS
Nonstop2h 12m
Breeze Airways
Mon 6/156:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/16$147
This Mytrip deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:57 am
SYR
-
CHS
1 stop9h 32m
Breeze Airways
Fri 5/226:30 am
CHS
-
SYR
Nonstop2h 07m
Breeze Airways
Deal found 3/14$160
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:55 pm
SYR
-
CHS
Nonstop2h 19m
Breeze Airways
Mon 4/206:05 am
CHS
-
SYR
Nonstop2h 08m
Breeze Airways
Deal found 3/13$162
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:36 pm
SYR
-
MYR
Nonstop1h 59m
Allegiant Air
Sun 8/25:25 pm
MYR
-
SYR
Nonstop1h 54m
Allegiant Air
Deal found 3/13$182
This Cheapflightsfares deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/223:43 pm
SYR
-
MYR
Nonstop2h 10m
Allegiant Air
Sun 3/296:58 pm
MYR
-
SYR
Nonstop1h 59m
Allegiant Air
Deal found 3/15$186
This Cheapflightsfares deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/174:15 pm
SYR
-
MYR
Nonstop1h 55m
Allegiant Air
Sun 5/245:32 pm
MYR
-
SYR
Nonstop1h 50m
Allegiant Air
Deal found 3/13$188
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:15 pm
SYR
-
MYR
Nonstop1h 55m
Multiple Airlines
Thu 4/3011:52 am
MYR
-
SYR
1 stop22h 49m
Multiple Airlines
Deal found 3/15$190

Find flight deals from Syracuse to South Carolina

Keep the following information in mind while searching for Syracuse to South Carolina flight deals. Data was last updated March 16, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$116
(Booking.com)

One-way from

$54
(Super.com)

Popular in

February

Cheapest in

September

Average price

$262

Good round-trip deal

$158 or less

Good one-way deal

$104 or less
Provider with most accurate pricing for Syracuse Hancock Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Syracuse Hancock Intl-Myrtle Beach Intl flights.
Search Deals
From Syracuse Hancock Intl to South Carolina
Search Deals
One-way flight from Syracuse Hancock Intl to South Carolina
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($47 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Syracuse Hancock Intl to South Carolina.
Search Deals
Price to beat on a one-way flight from Syracuse Hancock Intl to South Carolina.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Syracuse to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
Use the filters below to find and compare flights from Syracuse to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Wed 5/27

11:57 am-9:29 pm

1 stop9h 32m

Charleston

Fri 6/5

6:30 am-8:37 am

Nonstop2h 07m

$208

SyracuseCharlotte

SYR - CLT

SYRCLT

Syracuse Hancock Intl

Thu 4/23

5:31 am-10:14 am

1 stop4h 43m

Charlotte Douglas

Sun 4/26

6:00 am-11:11 am

1 stop5h 11m

$227

SyracuseCharlotte

SYR - CLT

SYRCLT

Syracuse Hancock Intl

Fri 4/24

6:30 am-1:23 pm

1 stop6h 53m

Charlotte Douglas

Sun 4/26

6:00 am-11:11 am

1 stop5h 11m

$227

SyracuseCharlotte

SYR - CLT

SYRCLT

Syracuse Hancock Intl

Thu 4/30

6:30 am-1:23 pm

1 stop6h 53m

Charlotte Douglas

Sun 5/3

6:00 am-11:11 am

1 stop5h 11m

$227

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Sat 4/25

6:15 am-11:03 am

1 stop4h 48m

Myrtle Beach Intl

Sat 5/2

6:11 pm-12:03 am

1 stop5h 52m

$251

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Mon 5/11

10:00 am-7:13 pm

1 stop9h 13m

Charleston

Fri 5/15

5:59 pm-11:59 pm

1 stop6h 00m

$269

SyracuseGreenville

SYR - GSP

SYRGSP

Syracuse Hancock Intl

Tue 4/28

6:25 pm-11:56 pm

1 stop5h 31m

Greenville

Sat 5/2

5:50 pm-12:03 am

1 stop6h 13m

$271

SyracuseMyrtle Beach

SYR - MYR

SYRMYR

Syracuse Hancock Intl

Wed 4/15

6:30 am-11:03 am

1 stop4h 33m

Myrtle Beach Intl

Tue 4/21

3:49 pm-12:43 am

2 stops8h 54m

$276

SyracuseCharleston

SYR - CHS

SYRCHS

Syracuse Hancock Intl

Sun 4/26

6:30 am-12:25 pm

1 stop5h 55m

Charleston

Sat 5/2

6:00 am-2:16 pm

2 stops8h 16m

$288

SyracuseSavannah

SYR - SAV

SYRSAV

Syracuse Hancock Intl

Thu 7/9

5:00 pm-10:31 pm

1 stop5h 31m

Savannah/Hilton Head

Mon 7/13

6:50 pm-11:59 pm

1 stop5h 09m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Syracuse to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Syracuse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Syracuse to South Carolina

What is the cheapest month to book a flight from Syracuse to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Syracuse to South Carolina (average of $48). Flying from Syracuse to South Carolina in August is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SYR to SC?

Find hourly flight availability from Syracuse to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 16, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 39% on flights from Syracuse to South Carolina by exploring options for tickets at noon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 16, 2026.
Get a feel of what it's like to fly with Breeze Airways,Delta, andUnited Airlines from Syracuse to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Breeze Airways
8.1
Very good
271 reviews
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Delta
7.9
Good
8,288 reviews
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
United Airlines
7.4
Good
9,431 reviews
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
Allegiant Air
7.3
Good
712 reviews
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.
American Airlines
7.1
Good
11,468 reviews
Breeze Airways
8.1
Very good
271 reviews

Crew

8.7

Boarding

8.3

Comfort

8.2

Food

6.6

Overall

8.1

Entertainment

6.6

Reviews

1 / 17
2.0
Mediocre

Justine,Jan 2026

RDU - MCO

1/10, I have never experienced the amount of delays, my flight was supposed to board at 8:34pm, we didn’t board until 3:35am from RDU. The staff got rude and very disrespectful when you asked what was going on it was like we didn’t board until something wrong or were pestering them for answers. I was 1 question 1 time, they were not communicating with us at all. So when our plane was now 6+ hrs delayed and nothing was being said to us .. yeah I think we have a right to ask a question. Everything took so long and was such a process; I have never experienced this before and I’m a frequent flyer, breeze makes spirit airlines look like a 100/10 airline.

Related info for your journey

Find useful and relevant information for your journey from Syracuse to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Syracuse to South Carolina?

    Most people fly from Syracuse Hancock Intl (SYR) if they book a flight from Syracuse to South Carolina. Syracuse Hancock Intl is conveniently located just 4.8 mi from Syracuse’s city center.

  • How popular is this Syracuse to South Carolina flight route?

    Within the past month, 1 users have taken a look at flights from Syracuse Hancock Intl to South Carolina.

  • How long is the flight from Syracuse to South Carolina?

    Departing from Syracuse to South Carolina will take you 4h 43m. There are 603 mi between Syracuse and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Syracuse to South Carolina one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $53. However, be on the lookout for offers from Breeze Airways and American Airlines, as they are both options that can get you from Syracuse to South Carolina for a low price.

  • What are the most popular routes from Syracuse to South Carolina?

    The most popular route from Syracuse to South Carolina is Syracuse Hancock Intl - Charlotte Douglas. You may also consider Syracuse Hancock Intl - Myrtle Beach Intl or Syracuse Hancock Intl - Savannah/Hilton Head.

  • What are the cheapest flights from Syracuse to South Carolina?

    On average you can expect to pay $143 for a flight from Syracuse to South Carolina. The cheapest flight overall is $59 while the most popular route, (Syracuse Hancock Intl - Charlotte Douglas) is currently priced at $262.

  • Can I find deals for flights from Syracuse to South Carolina that include hotel bookings?

    Yes. In addition to deals on Syracuse to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Syracuse to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Syracuse to South Carolina.

  • Can I find deals for business class flights from Syracuse to South Carolina?

    Yes. Cheapflights offers flight deals from Syracuse to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Syracuse to South Carolina?

    Currently, April is the cheapest month in which you can book a flight from Syracuse to South Carolina (average of $48). Flying from Syracuse to South Carolina in August is currently the most expensive (average of $115). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Syracuse to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Syracuse to South Carolina

Discover the top 6 airlines that operate flights from Syracuse to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$95Average$180FlexibilityNo cancel feeOn-time88%
Breeze AirwaysCheapest$98Average$163FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$116Average$301FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$131Average$239FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$134Average$367FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$371FlexibilityNo cancel feeOn-time71%

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