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South Carolina

$76+ Cheap flights from St. Louis (STL) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from St. Louis to South Carolina

Keep the following information in mind while searching for St. Louis to South Carolina flight deals. Data was last updated junio 12, 2025.

Round-trip from

$157
(American Airlines)

One-way from

$76
(FlightHub)

Popular in

December

Cheapest in

July

Average price

$392

Good round-trip deal

$425 or less
From Lambert-St Louis to South Carolina
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One-way flight from Lambert-St Louis to South Carolina
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Highest demand for flights based on searches. 8% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from Lambert-St Louis to South Carolina.
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Find flight deals from St. Louis to South Carolina

Cheapest flights from St. Louis to South Carolina
Explore the most affordable flight options available from St. Louis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/104:28 pmSTL - MYR
1 stop6h 34mAmerican Airlines
mar. 7/157:50 pmMYR - STL
1 stop5h 09mAmerican Airlines
Deal found 6/10$157
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/271:40 pmSTL - MYR
Nonstop1h 55mSouthwest
jue. 7/317:55 pmMYR - STL
1 stop4h 25mSouthwest
Deal found 6/10$167
This FlightHub deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/48:44 amSTL - MYR
1 stop7h 15mSpirit Airlines
jue. 9/1112:18 pmMYR - STL
1 stop20h 31mSpirit Airlines
Deal found 6/12$174
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 7/1010:47 amSTL - CLT
1 stop5h 37mSpirit Airlines
dom. 7/136:29 pmCLT - STL
1 stop16h 23mSpirit Airlines
Deal found 6/10$183
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 7/277:11 pmSTL - MYR
1 stop3h 48mDelta
jue. 7/316:00 amMYR - STL
1 stop4h 41mDelta
Deal found 6/10$197
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:26 amSTL - CLT
Nonstop1h 58mAmerican Airlines
jue. 8/1410:55 pmCLT - STL
Nonstop2h 00mAmerican Airlines
Deal found 6/11$197
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/188:44 amSTL - CHS
1 stop23h 49mSpirit Airlines
dom. 9/2110:28 amCHS - STL
1 stop22h 21mSpirit Airlines
Deal found 6/11$202
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/44:40 pmSTL - CLT
1 stop5h 20mSouthwest
jue. 8/77:50 pmCLT - STL
Nonstop2h 00mSouthwest
Deal found 6/10$207
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/76:00 amSTL - SAV
1 stop4h 37mAmerican Airlines
lun. 8/117:37 amSAV - STL
1 stop5h 58mAmerican Airlines
Deal found 6/10$217
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:00 amSTL - CLT
1 stop4h 01mDelta
jue. 8/149:53 amCLT - STL
1 stop5h 44mDelta
Deal found 6/10$217
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/79:50 amSTL - SAV
2 stops7h 35mSouthwest
lun. 8/115:30 pmSAV - STL
1 stop6h 05mSouthwest
Deal found 6/10$222
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/96:15 amSTL - CAE
1 stop8h 17mAmerican Airlines
mié. 7/165:15 amCAE - STL
1 stop4h 04mAmerican Airlines
Deal found 6/11$230

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from St. Louis to South Carolina that are best for you.

Fly from

St. Louis

Fly to

South Carolina

Route

Depart

Return

Price

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 7/10

4:28 pm-12:02 am

1 stop6h 34m

Myrtle Beach Intl

mar. 7/15

7:50 pm-11:59 pm

1 stop5h 09m

$157

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

dom. 7/27

1:40 pm-4:35 pm

Nonstop1h 55m

Myrtle Beach Intl

jue. 7/31

7:55 pm-11:20 pm

1 stop4h 25m

$167

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

jue. 9/4

8:44 am-4:59 pm

1 stop7h 15m

Myrtle Beach Intl

jue. 9/11

12:18 pm-7:49 am

1 stop20h 31m

$174

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

jue. 7/10

10:47 am-5:24 pm

1 stop5h 37m

Charlotte Douglas

dom. 7/13

6:29 pm-9:52 am

1 stop16h 23m

$183

St. LouisMyrtle Beach

STL - MYR

STLMYR

Lambert-St Louis

dom. 7/27

7:11 pm-11:59 pm

1 stop3h 48m

Myrtle Beach Intl

jue. 7/31

6:00 am-9:41 am

1 stop4h 41m

$197

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

mar. 8/12

6:26 am-9:24 am

Nonstop1h 58m

Charlotte Douglas

jue. 8/14

10:55 pm-11:55 pm

Nonstop2h 00m

$197

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

lun. 8/4

4:40 pm-11:00 pm

1 stop5h 20m

Charlotte Douglas

jue. 8/7

7:50 pm-8:50 pm

Nonstop2h 00m

$207

St. LouisCharlotte

STL - CLT

STLCLT

Lambert-St Louis

mar. 8/12

6:00 am-11:01 am

1 stop4h 01m

Charlotte Douglas

jue. 8/14

9:53 am-2:37 pm

1 stop5h 44m

$217

St. LouisSavannah

STL - SAV

STLSAV

Lambert-St Louis

jue. 8/7

6:00 am-11:37 am

1 stop4h 37m

Savannah/Hilton Head

lun. 8/11

7:37 am-12:35 pm

1 stop5h 58m

$217

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

jue. 7/17

10:47 am-9:53 am

1 stop22h 06m

Charleston

dom. 7/20

10:53 am-9:52 am

1 stop23h 59m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 60 results
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Best time to book a flight from St. Louis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to South Carolina

What is the cheapest month to book a flight from St. Louis to South Carolina?

Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SC?

Find hourly flight availability from St. Louis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

When flying from St. Louis to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated junio 12, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from St. Louis to South Carolina. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Spirit Airlines
6.3
Okay
8,052 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from St. Louis to South Carolina?

    For a flight from St. Louis to South Carolina, you will be flying from Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How popular is this St. Louis to South Carolina flight route?

    Within the past month, 6 users have taken a look at flights from Lambert-St Louis to South Carolina.

  • What are the cheapest airlines to fly from St. Louis to South Carolina one-way?

    The cheapest airlines for a one-way flight from St. Louis to South Carolina are Spirit Airlines ($76), Southwest ($79), and American Airlines ($84).

  • What are the most popular routes from St. Louis to South Carolina?

    While some choose either Lambert-St Louis - Charleston or Lambert-St Louis - Savannah/Hilton Head, Lambert-St Louis - Charlotte Douglas is the most popular route from St. Louis to South Carolina.

  • What are the cheapest flights from St. Louis to South Carolina?

    Looking for the cheapest flight from St. Louis to South Carolina? While on average our users pay $447, our data indicates the cheapest price to be $346. The most popular route (Lambert-St Louis - Charlotte Douglas), is priced around $183.

  • Can I find deals for flights from St. Louis to South Carolina that include hotel bookings?

    Yes. In addition to deals on St. Louis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to South Carolina.

  • Can I find deals for business class flights from St. Louis to South Carolina?

    Yes. Cheapflights offers flight deals from St. Louis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from St. Louis to South Carolina (average of $217). Flying from St. Louis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for St. Louis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from St. Louis to South Carolina

Discover the top 5 airlines that operate flights from St. Louis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$112Average$198FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$188Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$196Average$376FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$270Average$640FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$305Average$402FlexibilityNo cancel feeOn-time63%

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