$111+ Cheap flights from Oregon to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — CHS
Jun 3 — Jun 101
Round-trip
1 adult, Economy
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Find cheap flights from Oregon to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Oregon to South Carolina
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Cheapest flights from Oregon to South CarolinaExplore the most affordable flight options available from Oregon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
Explore the most affordable flight options available from Oregon to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Thu 5/286:18 pm
MYR
- PDX
2 stops49h 28m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Thu 5/286:18 pm
MYR
- PDX
2 stops49h 28m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
Sat 5/3010:03 am
MYR
- PDX
1 stop30h 51m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$318
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:40 pm
PDX
- CAE
1 stop10h 22m
American Airlines
Tue 6/96:03 pm
CAE
- PDX
1 stop8h 56m
American Airlines
Deal found 5/3![American Airlines logo]()
$351
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Sat 5/303:17 pm
MYR
- PDX
2 stops25h 37m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 pm
PDX
- CAE
1 stop7h 26m
United Airlines
Tue 6/910:31 am
CAE
- PDX
2 stops11h 16m
United Airlines
Deal found 5/3![United Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:39 pm
PDX
- CAE
1 stop8h 36m
Delta
Sun 5/315:40 am
CAE
- PDX
1 stop7h 26m
Delta
Deal found 4/30![Delta logo]()
$360
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:12 pm
PDX
- CAE
2 stops11h 02m
Delta
Tue 6/95:35 am
CAE
- PDX
2 stops14h 07m
Delta
Deal found 5/3![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
PDX
- CAE
2 stops13h 47m
Delta
Sun 5/315:40 am
CAE
- PDX
1 stop7h 26m
Delta
Deal found 4/30![Delta logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:44 pm
PDX
- SAV
1 stop29h 54m
Allegiant Air
Sun 6/77:30 am
SAV
- PDX
1 stop9h 18m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Wed 5/273:17 pm
MYR
- PDX
2 stops25h 37m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2510:40 pm
PDX
- CAE
1 stop10h 22m
American Airlines
Mon 6/17:21 pm
CAE
- PDX
1 stop8h 29m
American Airlines
Deal found 5/4![American Airlines logo]()
$369
Best flights from Oregon to South CarolinaDiscover carefully curated flight deals from Oregon to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
Discover carefully curated flight deals from Oregon to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 4, 2026.
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 pm
PDX
- CAE
1 stop7h 26m
United Airlines
Tue 6/910:31 am
CAE
- PDX
2 stops11h 16m
United Airlines
Deal found 5/3![United Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:06 pm
PDX
- CAE
1 stop6h 41m
Delta
Sun 5/313:53 pm
CAE
- PDX
1 stop8h 53m
Delta
Deal found 5/1![Delta logo]()
$360
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:49 am
PDX
- CAE
1 stop6h 55m
American Airlines
Mon 6/17:21 pm
CAE
- PDX
1 stop8h 29m
American Airlines
Deal found 5/1![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:20 pm
PDX
- CHS
1 stop9h 50m
Southwest
Tue 7/74:50 pm
CHS
- PDX
1 stop8h 45m
Southwest
Deal found 5/1![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:12 pm
PDX
- CAE
2 stops11h 02m
Delta
Tue 6/95:35 am
CAE
- PDX
2 stops14h 07m
Delta
Deal found 5/3![Delta logo]()
$361
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:07 am
PDX
- CHS
1 stop6h 57m
United Airlines
Sat 10/247:00 am
CHS
- PDX
1 stop8h 00m
United Airlines
Deal found 5/1![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:40 am
BOI
- SAV
2 stops10h 00m
Southwest
Tue 6/231:25 pm
SAV
- BOI
2 stops11h 30m
Southwest
Deal found 5/4![Southwest logo]()
$393
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:59 pm
PDX
- CAE
2 stops10h 21m
American Airlines
Mon 6/86:03 pm
CAE
- PDX
1 stop8h 56m
American Airlines
Deal found 5/4![American Airlines logo]()
$394
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:40 pm
PDX
- CHS
1 stop7h 43m
United Airlines
Tue 7/710:00 am
CHS
- PDX
2 stops11h 47m
United Airlines
Deal found 5/1![United Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:12 pm
PDX
- GSP
1 stop8h 43m
Delta
Wed 6/33:00 pm
GSP
- PDX
2 stops11h 01m
Delta
Deal found 5/2![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:45 am
PDX
- CHS
2 stops8h 35m
Southwest
Thu 10/221:15 pm
CHS
- PDX
2 stops8h 45m
Southwest
Deal found 5/3![Southwest logo]()
$396
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:05 am
PDX
- AGS
1 stop7h 25m
American Airlines
Wed 6/36:27 pm
AGS
- PDX
1 stop8h 32m
American Airlines
Deal found 5/3![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:51 am
PDX
- CHS
1 stop8h 00m
United Airlines
Wed 6/311:31 am
CHS
- PDX
1 stop10h 16m
United Airlines
Deal found 4/30![United Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
PDX
- GSP
1 stop8h 53m
Delta
Wed 6/33:00 pm
GSP
- PDX
2 stops11h 01m
Delta
Deal found 4/29![Delta logo]()
$388
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:55 pm
PDX
- SAV
2 stops10h 45m
Southwest
Tue 6/97:50 am
SAV
- PDX
1 stop10h 35m
Southwest
Deal found 5/1![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:30 pm
PDX
- CHS
1 stop7h 46m
United Airlines
Mon 6/86:30 pm
CHS
- PDX
1 stop8h 23m
United Airlines
Deal found 4/30![United Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:20 am
PDX
- GSP
2 stops9h 23m
Delta
Sat 5/3011:45 am
GSP
- PDX
2 stops11h 51m
Delta
Deal found 5/4![Delta logo]()
$401
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:00 am
PDX
- GSP
2 stops9h 40m
Southwest
Sat 6/61:55 pm
GSP
- PDX
1 stop8h 45m
Southwest
Deal found 5/2![Southwest logo]()
$404
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:49 am
PDX
- MYR
1 stop6h 43m
American Airlines
Thu 7/24:16 pm
MYR
- PDX
2 stops10h 48m
American Airlines
Deal found 5/2![American Airlines logo]()
$460
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:40 pm
PDX
- SAV
1 stop7h 43m
United Airlines
Tue 6/911:30 am
SAV
- PDX
1 stop10h 17m
United Airlines
Deal found 5/1![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:10 am
EUG
- CLT
1 stop8h 42m
Delta
Thu 6/46:02 pm
CLT
- EUG
1 stop8h 41m
Delta
Deal found 5/4![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1310:40 pm
PDX
- MYR
1 stop9h 15m
American Airlines
Sat 6/206:12 pm
MYR
- PDX
1 stop8h 47m
American Airlines
Deal found 5/2![American Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:10 am
PDX
- SAV
2 stops10h 10m
Southwest
Tue 6/25:00 pm
SAV
- PDX
1 stop9h 10m
Southwest
Deal found 5/2![Southwest logo]()
$427
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/118:25 am
BOI
- CLT
1 stop6h 31m
Delta
Tue 6/166:09 pm
CLT
- BOI
1 stop8h 00m
Delta
Deal found 5/1![Delta logo]()
$416
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:00 am
PDX
- MYR
2 stops11h 45m
Southwest
Tue 6/167:00 am
MYR
- PDX
2 stops11h 05m
Southwest
Deal found 5/3![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/1510:40 pm
PDX
- CHS
1 stop8h 28m
United Airlines
Mon 6/226:00 am
CHS
- PDX
1 stop8h 38m
United Airlines
Deal found 4/30![United Airlines logo]()
$439
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:59 am
PDX
- AGS
1 stop8h 31m
American Airlines
Thu 7/234:00 pm
AGS
- PDX
1 stop9h 51m
American Airlines
Deal found 5/3![American Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:41 pm
EUG
- CLT
2 stops16h 14m
Delta
Sat 5/3011:00 am
CLT
- EUG
2 stops14h 31m
Delta
Deal found 5/2![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
BOI
- SAV
2 stops11h 20m
Southwest
Tue 6/304:50 pm
SAV
- BOI
2 stops9h 35m
Southwest
Deal found 5/3![Southwest logo]()
$435
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:48 pm
PDX
- SAV
1 stop7h 35m
United Airlines
Mon 6/83:40 pm
SAV
- PDX
1 stop10h 08m
United Airlines
Deal found 4/30![United Airlines logo]()
$454
Last-minute flights from Oregon to South CarolinaDiscover last-minute flight deals from Oregon to South Carolina. Data last updated May 4, 2026 and is based on user searches.
Discover last-minute flight deals from Oregon to South Carolina. Data last updated May 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Thu 5/286:18 pm
MYR
- PDX
2 stops49h 28m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Thu 5/286:18 pm
MYR
- PDX
2 stops49h 28m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Allegiant Air
Sat 5/3010:03 am
MYR
- PDX
1 stop30h 51m
Allegiant Air
Deal found 5/1![Allegiant Air logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Sat 5/303:17 pm
MYR
- PDX
2 stops25h 37m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- MYR
1 stop21h 34m
Multiple Airlines
Wed 5/273:17 pm
MYR
- PDX
2 stops25h 37m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$366
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2510:40 pm
PDX
- CAE
1 stop10h 22m
American Airlines
Mon 6/17:21 pm
CAE
- PDX
1 stop8h 29m
American Airlines
Deal found 5/4![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:39 pm
PDX
- CAE
1 stop8h 36m
Delta
Sun 5/315:40 am
CAE
- PDX
1 stop7h 26m
Delta
Deal found 4/30![Delta logo]()
$360
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
PDX
- CAE
2 stops13h 47m
Delta
Sun 5/315:40 am
CAE
- PDX
1 stop7h 26m
Delta
Deal found 4/30![Delta logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:44 pm
PDX
- SAV
1 stop29h 54m
Allegiant Air
Sun 6/77:30 am
SAV
- PDX
1 stop9h 18m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:40 pm
PDX
- CAE
1 stop10h 22m
American Airlines
Tue 6/96:03 pm
CAE
- PDX
1 stop8h 56m
American Airlines
Deal found 5/3![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:30 pm
PDX
- CAE
1 stop7h 26m
United Airlines
Tue 6/910:31 am
CAE
- PDX
2 stops11h 16m
United Airlines
Deal found 5/3![United Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/211:12 pm
PDX
- CAE
2 stops11h 02m
Delta
Tue 6/95:35 am
CAE
- PDX
2 stops14h 07m
Delta
Deal found 5/3![Delta logo]()
$361
One-way flights from Oregon to South CarolinaSearch for one-way flight options from Oregon to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
Search for one-way flight options from Oregon to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 4, 2026.
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:20 pm
PDX
- CLT
1 stop25h 05m
Frontier
Deal found 4/30![Frontier logo]()
$111
This Booking.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:15 am
PDX
- CLT
1 stop16h 44m
Frontier
Deal found 5/3![Frontier logo]()
$116
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:16 pm
PDX
- CLT
1 stop22h 02m
Frontier
Deal found 4/29![Frontier logo]()
$117
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:35 pm
PDX
- CLT
1 stop26h 44m
Frontier
Deal found 4/30![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2312:35 pm
PDX
- CLT
2 stops24h 25m
Frontier
Deal found 4/29![Frontier logo]()
$136
This CheapOair deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:26 pm
PDX
- CLT
1 stop29h 57m
Frontier
Deal found 4/30![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- SAV
1 stop29h 53m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/212:44 pm
PDX
- SAV
1 stop29h 09m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:44 pm
PDX
- CLT
3 stops44h 27m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:44 pm
PDX
- SAV
1 stop29h 54m
Allegiant Air
Deal found 5/3![Allegiant Air logo]()
$151
This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:15 am
PDX
- CLT
1 stop16h 44m
Frontier
Deal found 4/30![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2512:35 pm
PDX
- CLT
2 stops39h 24m
Frontier
Deal found 4/29![Frontier logo]()
$153
Find flight deals from Oregon to South Carolina
Keep the following information in mind while searching for Oregon to South Carolina flight deals. Data was last updated May 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (Kiwi.com) |
One-way from | $111 (Booking.com) |
Popular in | April |
Cheapest in | January |
Average price | $511 |
Cheapflights Fare Finder
Customize your flight search to find flights from Oregon to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
Use the filters below to find and compare flights from Oregon to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Tue 6/2
11:30 pm-9:56 am
1 stop7h 26m
Columbia Metropolitan
Tue 6/9
10:31 am-6:47 pm
2 stops11h 16m
$356
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Thu 5/28
2:06 pm-11:47 pm
1 stop6h 41m
Columbia Metropolitan
Sun 5/31
3:53 pm-9:46 pm
1 stop8h 53m
$360
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Tue 6/2
11:12 pm-1:14 pm
2 stops11h 02m
Columbia Metropolitan
Tue 6/9
5:35 am-4:42 pm
2 stops14h 07m
$361
PortlandColumbia
PDX - CAE
PDXCAE
Portland
Mon 5/25
5:49 am-3:44 pm
1 stop6h 55m
Columbia Metropolitan
Mon 6/1
7:21 pm-12:50 am
1 stop8h 29m
$369
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Tue 6/30
9:20 pm-10:10 am
1 stop9h 50m
Charleston
Tue 7/7
4:50 pm-10:35 pm
1 stop8h 45m
$377
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Sat 10/17
11:07 am-9:04 pm
1 stop6h 57m
Charleston
Sat 10/24
7:00 am-12:00 pm
1 stop8h 00m
$377
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Tue 6/30
11:40 pm-10:23 am
1 stop7h 43m
Charleston
Tue 7/7
10:00 am-6:47 pm
2 stops11h 47m
$382
PortlandCharleston
PDX - CHS
PDXCHS
Portland
Mon 6/1
10:51 am-9:51 pm
1 stop8h 00m
Charleston
Wed 6/3
11:31 am-6:47 pm
1 stop10h 16m
$386
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Tue 6/2
11:12 pm-10:55 am
1 stop8h 43m
Greenville
Wed 6/3
3:00 pm-11:01 pm
2 stops11h 01m
$388
PortlandGreenville
PDX - GSP
PDXGSP
Portland
Wed 5/27
7:00 am-6:53 pm
1 stop8h 53m
Greenville
Wed 6/3
3:00 pm-11:01 pm
2 stops11h 01m
$388
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Oregon to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Oregon with our price prediction graph.
PDX-MYR
PDX-CAE
PDX-SAV
PDX-CLT
BOI-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Oregon to South Carolina
USOR-USSC
PDX-MYR
PDX-CAE
PDX-SAV
PDX-CLT
How far ahead should I book a flight from Oregon to South Carolina?
To ensure you get the cheapest price possible for a flight from Oregon to South Carolina, you should look to book at least 45 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Oregon to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Oregon to South Carolina (average of $129). Flying from Oregon to South Carolina in December is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Oregon to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 4, 2026.
Read through reviews of airlines operating flights from Oregon to South Carolina, such as Alaska Airlines,Southwest, andDelta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Entertainment
7.0
Overall
7.9
Boarding
8.1
Comfort
7.8
Food
7.1
Crew
8.5
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Related info for your journey
Find useful and relevant information for your journey from Oregon to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Oregon to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Oregon to South Carolina by cabin class
Find flights from Oregon to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Oregon and South Carolina flights
Browse other Oregon and South Carolina flight options. Last updated on May 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Oregon after your stay in South Carolina
Oregon to South Carolina flights
Consider these flights traveling from Oregon to South Carolina.
Top 5 airlines flying from Oregon to South Carolina
Discover the top 5 airlines that operate flights from Oregon to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$476 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$513 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$294 | Average$562 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$543 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$329 | Average$540 | FlexibilityNo cancel fee | On-time63% |