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South Carolina

$226+ Cheap flights from Moline (MLI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — CHS
Aug 27 — Sep 31
Thu 8/27
Thu 9/3
1 adult, Economy
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Cheap flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina
Explore the most affordable flight options available from Moline to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.

This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:16 pm
MLI
-
CHS
1 stop5h 43m
Delta
Sun 9/137:05 am
CHS
-
MLI
1 stop4h 08m
Delta
Deal found 7/26$295
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:00 am
MLI
-
SAV
1 stop5h 19m
Delta
Tue 11/2412:45 pm
SAV
-
MLI
1 stop4h 37m
Delta
Deal found 7/26$301
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:09 pm
MLI
-
CHS
1 stop5h 50m
Delta
Tue 9/86:05 am
CHS
-
MLI
1 stop5h 08m
Delta
Deal found 7/24$305
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:04 pm
MLI
-
SAV
1 stop5h 53m
Delta
Tue 10/275:30 am
SAV
-
MLI
1 stop5h 52m
Delta
Deal found 7/26$310
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:00 am
MLI
-
SAV
1 stop7h 00m
Delta
Tue 9/156:45 am
SAV
-
MLI
1 stop4h 28m
Delta
Deal found 7/25$311
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:00 am
MLI
-
SAV
1 stop6h 16m
American Airlines
Tue 10/273:28 pm
SAV
-
MLI
2 stops9h 43m
American Airlines
Deal found 7/25$315
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:05 pm
MLI
-
CHS
1 stop5h 55m
American Airlines
Mon 8/317:00 am
CHS
-
MLI
1 stop5h 13m
American Airlines
Deal found 7/26$319
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:21 pm
MLI
-
MYR
1 stop4h 05m
American Airlines
Fri 9/115:45 pm
MYR
-
MLI
1 stop4h 24m
American Airlines
Deal found 7/24$319
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:13 pm
MLI
-
SAV
1 stop5h 45m
Delta
Thu 11/266:00 am
SAV
-
MLI
1 stop5h 20m
Delta
Deal found 7/26$319
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:16 pm
MLI
-
CAE
1 stop5h 33m
Delta
Sun 9/275:40 am
CAE
-
MLI
1 stop5h 33m
Delta
Deal found 7/26$319
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:20 pm
MLI
-
GSP
1 stop4h 07m
American Airlines
Wed 12/212:45 pm
GSP
-
MLI
1 stop5h 16m
American Airlines
Deal found 7/26$319
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:16 pm
MLI
-
SAV
1 stop5h 39m
Delta
Thu 9/175:30 am
SAV
-
MLI
1 stop5h 43m
Delta
Deal found 7/25$320

Find flight deals from Moline to South Carolina

Keep the following information in mind while searching for Moline to South Carolina flight deals. Data was last updated July 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$295
(Delta)

One-way from

$226
(Kiwi.com)

Popular in

August

Cheapest in

November

Average price

$450
Provider with most accurate pricing for Moline Quad-City-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Moline Quad-City-Myrtle Beach Intl flights.
Search Deals
From Moline Quad-City to South Carolina
Search Deals
One-way flight from Moline Quad-City to South Carolina
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 9/9

5:16 pm-11:59 pm

1 stop5h 43m

Charleston

Sun 9/13

7:05 am-10:13 am

1 stop4h 08m

$295

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 11/11

6:00 am-11:47 am

1 stop4h 47m

Charleston

Mon 11/16

7:10 pm-10:58 pm

1 stop4h 48m

$295

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Sat 11/21

5:13 pm-11:58 pm

1 stop5h 45m

Savannah/Hilton Head

Tue 11/24

12:45 pm-4:22 pm

1 stop4h 37m

$301

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Thu 9/3

5:09 pm-11:59 pm

1 stop5h 50m

Charleston

Tue 9/8

6:05 am-10:13 am

1 stop5h 08m

$305

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 10/23

5:04 pm-11:57 pm

1 stop5h 53m

Savannah/Hilton Head

Tue 10/27

6:31 pm-10:30 pm

1 stop4h 59m

$310

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Thu 11/19

5:13 pm-11:58 pm

1 stop5h 45m

Savannah/Hilton Head

Tue 11/24

12:45 pm-4:22 pm

1 stop4h 37m

$310

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 10/23

6:00 am-1:16 pm

1 stop6h 16m

Savannah/Hilton Head

Tue 10/27

3:28 pm-12:11 am

2 stops9h 43m

$315
Quickest round-trip

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Wed 8/26

8:14 am-1:32 pm

1 stop4h 18m

Greenville

Wed 9/2

6:30 am-9:54 am

1 stop4h 24m

$319

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Thu 11/26

4:20 pm-9:27 pm

1 stop4h 07m

Greenville

Wed 12/2

12:45 pm-5:01 pm

1 stop5h 16m

$319

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 8/28

11:08 am-5:38 pm

1 stop5h 30m

Charleston

Mon 8/31

1:01 pm-4:25 pm

1 stop4h 24m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 45 resultsSorted by cheapest first
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5

Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Moline to South Carolina (average of $309). Flying from Moline to South Carolina in April is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Moline to South Carolina?

Airfare is typical for this route at the moment.
Moline to South Carolina flights typically cost between $284 and $448 in September.
The cheapest round-trip price found within the last 5 days was $295 on Delta (Sep 9-Sep 13).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 28, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Moline to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,490 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
Delta
7.8
Good
8,490 reviews
Delta
7.8
Good
8,490 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
United Airlines
7.4
Good
10,049 reviews
Delta
7.8
Good
8,490 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional
American Airlines
7.1
Good
11,845 reviews
Delta
7.8
Good
8,490 reviews

Comfort

7.8

Overall

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
10.0
Excellent

Anonymous,May 2026

SEA - KOA

The snacks were not very good, not everyone was very friendly and professional

Related info for your journey

Find useful and relevant information for your journey from Moline to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • How long is the flight from Moline to South Carolina?

    There are many flights that can get you from Moline to South Carolina in 4h 15m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. Airlines will cover a distance of 728 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Moline to South Carolina?

    Most travelers choose Moline Quad-City - Charlotte Douglas, Moline Quad-City - Myrtle Beach Intl or Moline Quad-City - Savannah/Hilton Head when deciding on the best route from Moline to South Carolina.

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, September is the cheapest month in which you can book a flight from Moline to South Carolina (average of $309). Flying from Moline to South Carolina in April is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Moline to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Moline to South Carolina

Discover the top 3 airlines that operate flights from Moline to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$168Average$363FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$430FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$260Average$430FlexibilityNo cancel feeOn-time71%

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