South Carolina

$180+ Cheap flights from Moline (MLI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — CHS
Jun 17 — Jun 241
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Moline to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Moline to South Carolina

Keep the following information in mind while searching for Moline to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$219
(American Airlines)

One-way from

$180
(Mytrip)

Popular in

June

Cheapest in

February

Average price

$550
From Moline Quad-City to South Carolina
One-way flight from Moline Quad-City to South Carolina
Highest demand for flights based on searches. 6% potential increase in price ($24 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
Average for round-trip flights in June 2025

Find flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina
Explore the most affordable flight options available from Moline to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/214:31 pmMLI - SAV
1 stop6h 02mAmerican Airlines
Sat 10/253:59 pmSAV - MLI
1 stop6h 49mAmerican Airlines
Deal found 6/11$219
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:27 pmMLI - CHS
1 stop5h 32mDelta
Fri 7/116:23 pmCHS - MLI
1 stop4h 56mDelta
Deal found 6/11$249
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/165:26 pmMLI - MYR
1 stop5h 33mDelta
Tue 7/223:59 pmMYR - MLI
1 stop7h 20mDelta
Deal found 6/9$249
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:58 pmMLI - GSP
1 stop6h 00mAmerican Airlines
Mon 9/298:25 pmGSP - MLI
1 stop4h 02mAmerican Airlines
Deal found 6/10$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:15 amMLI - CHS
2 stops7h 34mAmerican Airlines
Fri 7/116:02 pmCHS - MLI
1 stop5h 06mAmerican Airlines
Deal found 6/11$254
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/56:00 amMLI - MYR
2 stops9h 48mAmerican Airlines
Sun 9/74:20 pmMYR - MLI
1 stop6h 49mAmerican Airlines
Deal found 6/12$254
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/275:27 pmMLI - CAE
1 stop5h 29mDelta
Fri 7/43:00 pmCAE - MLI
1 stop6h 23mDelta
Deal found 6/11$254
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:00 pmMLI - SAV
1 stop5h 59mDelta
Thu 10/236:30 pmSAV - MLI
1 stop5h 00mDelta
Deal found 6/9$274
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/284:20 pmMLI - CAE
1 stop6h 35mAmerican Airlines
Sat 7/54:12 pmCAE - MLI
1 stop7h 09mAmerican Airlines
Deal found 6/11$279
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/156:30 amMLI - CHS
2 stops6h 55mUnited Airlines
Mon 7/2111:25 amCHS - MLI
1 stop6h 18mUnited Airlines
Deal found 6/11$294
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:00 pmMLI - CLT
1 stop5h 54mDelta
Sat 11/111:00 amCLT - MLI
1 stop6h 22mDelta
Deal found 6/11$294
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:16 amMLI - CLT
Nonstop2h 09mAmerican Airlines
Sat 11/12:35 pmCLT - MLI
Nonstop2h 20mAmerican Airlines
Deal found 6/11$301

Cheapflights Fare Finder

Customize your flight search to find flights from Moline to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Moline

Fly to

South Carolina

Route

Depart

Return

Price

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Tue 10/21

4:31 pm-11:33 pm

1 stop6h 02m

Savannah/Hilton Head

Sat 10/25

3:59 pm-9:48 pm

1 stop6h 49m

$219

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 7/4

5:27 pm-11:59 pm

1 stop5h 32m

Charleston

Fri 7/11

6:23 pm-10:19 pm

1 stop4h 56m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Wed 7/16

5:26 pm-11:59 pm

1 stop5h 33m

Myrtle Beach Intl

Tue 7/22

3:59 pm-10:19 pm

1 stop7h 20m

$249

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Fri 9/26

3:58 pm-10:58 pm

1 stop6h 00m

Greenville

Mon 9/29

8:25 pm-11:27 pm

1 stop4h 02m

$249

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Fri 7/4

6:15 am-2:49 pm

2 stops7h 34m

Charleston

Fri 7/11

6:02 pm-10:08 pm

1 stop5h 06m

$254

MolineColumbia

MLI - CAE

MLICAE

Moline Quad-City

Fri 6/27

5:27 pm-11:56 pm

1 stop5h 29m

Columbia Metropolitan

Fri 7/4

3:00 pm-8:23 pm

1 stop6h 23m

$254

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Fri 9/5

6:00 am-4:48 pm

2 stops9h 48m

Myrtle Beach Intl

Sun 9/7

4:20 pm-10:09 pm

1 stop6h 49m

$254

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 10/17

5:00 pm-11:59 pm

1 stop5h 59m

Savannah/Hilton Head

Thu 10/23

6:30 pm-10:30 pm

1 stop5h 00m

$274

MolineColumbia

MLI - CAE

MLICAE

Moline Quad-City

Sat 6/28

4:20 pm-11:55 pm

1 stop6h 35m

Columbia Metropolitan

Sat 7/5

4:12 pm-10:21 pm

1 stop7h 09m

$279

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Tue 7/15

6:30 am-2:25 pm

2 stops6h 55m

Charleston

Mon 7/21

11:25 am-4:43 pm

1 stop6h 18m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 41 results
1
2
3
...
5

Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Moline to South Carolina, such as Delta, United Airlines and Allegiant Air. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Moline to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • What are the cheapest airlines to fly from Moline to South Carolina one-way?

    One-way options have recently been found by users for as low as $180 on American Airlines. Other airlines that offer cheap prices include Delta from $210 and United Airlines from $246 one-way.

  • What are the most popular routes from Moline to South Carolina?

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Moline to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Moline to South Carolina

Discover the top 3 airlines that operate flights from Moline to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$367FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$221Average$393FlexibilityNo cancel feeOn-time69%
DeltaCheapest$242Average$346FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.