HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$135+ Cheap flights from Moline (MLI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — CHS
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Moline to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Moline to South Carolina

Keep the following information in mind while searching for Moline to South Carolina flight deals. Data was last updated August 20, 2025.

Round-trip from

$249
(American Airlines)

One-way from

$135
(United Airlines)

Popular in

June

Cheapest in

February

Average price

$265
From Moline Quad-City to South Carolina
Search Deals
One-way flight from Moline Quad-City to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina
Explore the most affordable flight options available from Moline to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/156:32 pmMLI - CHS
1 stop4h 43mAmerican Airlines
Sat 10/187:45 pmCHS - MLI
1 stop4h 54mAmerican Airlines
Deal found 8/19$249
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:58 pmMLI - MYR
1 stop4h 11mAmerican Airlines
Tue 9/165:36 pmMYR - MLI
1 stop5h 49mAmerican Airlines
Deal found 8/18$249
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:04 pmMLI - SAV
1 stop5h 54mDelta
Tue 10/146:59 pmSAV - MLI
1 stop4h 21mDelta
Deal found 8/19$249
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/138:19 amMLI - GSP
1 stop4h 28mAmerican Airlines
Tue 9/167:36 amGSP - MLI
1 stop4h 14mAmerican Airlines
Deal found 8/19$249
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/54:59 pmMLI - CHS
1 stop5h 52mDelta
Tue 9/95:35 pmCHS - MLI
1 stop6h 13mDelta
Deal found 8/18$254
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:12 amMLI - MYR
1 stop4h 23mAmerican Airlines
Mon 11/246:05 amMYR - MLI
2 stops5h 48mAmerican Airlines
Deal found 8/18$254
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:00 amMLI - SAV
1 stop4h 29mAmerican Airlines
Sat 10/2511:02 amSAV - MLI
2 stops10h 33mAmerican Airlines
Deal found 8/18$254
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/258:10 pmMLI - CLT
1 stop19h 20mMultiple Airlines
Tue 11/410:19 amCLT - MLI
2 stops22h 40mMultiple Airlines
Deal found 8/19$257
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:59 pmMLI - CHS
1 stop5h 52mDelta
Sat 9/65:37 pmCHS - MLI
1 stop6h 11mDelta
Deal found 8/18$259
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:30 amMLI - SAV
1 stop7h 14mUnited Airlines
Mon 9/81:15 pmSAV - MLI
1 stop7h 12mUnited Airlines
Deal found 8/20$259
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/34:59 pmMLI - MYR
1 stop5h 50mDelta
Sat 9/612:49 pmMYR - MLI
2 stops10h 59mDelta
Deal found 8/17$264
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/316:04 amMLI - CHS
1 stop6h 13mAmerican Airlines
Sat 9/64:16 pmCHS - MLI
1 stop5h 09mAmerican Airlines
Deal found 8/20$265

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Moline

Fly to

South Carolina

Route

Depart

Return

Price

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 10/15

6:32 pm-12:15 am

1 stop4h 43m

Charleston

Sat 10/18

7:45 pm-11:39 pm

1 stop4h 54m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Wed 11/19

5:55 am-1:28 pm

1 stop6h 33m

Myrtle Beach Intl

Mon 11/24

6:45 pm-10:30 pm

1 stop4h 45m

$249

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Wed 9/17

3:26 pm-9:05 pm

1 stop4h 39m

Charleston

Wed 9/24

5:37 pm-10:25 pm

1 stop5h 48m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Sat 10/11

5:04 pm-11:58 pm

1 stop5h 54m

Savannah/Hilton Head

Wed 10/15

6:55 pm-10:20 pm

1 stop4h 25m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Sat 9/13

3:26 pm-11:08 pm

1 stop6h 42m

Myrtle Beach Intl

Thu 9/18

6:05 pm-10:11 pm

1 stop5h 06m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Tue 10/21

5:04 pm-11:58 pm

1 stop5h 54m

Savannah/Hilton Head

Sat 10/25

10:23 am-4:24 pm

1 stop7h 01m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Fri 9/12

3:58 pm-9:09 pm

1 stop4h 11m

Myrtle Beach Intl

Tue 9/16

5:36 pm-10:25 pm

1 stop5h 49m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Sat 10/11

5:04 pm-11:58 pm

1 stop5h 54m

Savannah/Hilton Head

Tue 10/14

6:59 pm-10:20 pm

1 stop4h 21m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Sat 9/27

3:26 pm-9:17 pm

1 stop4h 51m

Myrtle Beach Intl

Fri 10/3

12:12 pm-3:28 pm

1 stop4h 16m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Sat 9/13

3:26 pm-8:33 pm

1 stop4h 07m

Savannah/Hilton Head

Tue 9/16

7:03 pm-10:25 pm

1 stop4h 22m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 46 results
1
2
3
...
5

Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated August 20, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Moline to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,928 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Overall

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Moline to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • How long is the flight from Moline to South Carolina?

    There are many flights that can get you from Moline to South Carolina in 4h 43m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. Airlines will cover a distance of 824 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Moline to South Carolina one-way?

    One-way options have recently been found by users for as low as $135 on United Airlines. Other airlines that offer cheap prices include Delta from $239 and American Airlines from $244 one-way.

  • What are the most popular routes from Moline to South Carolina?

    Most travelers choose Moline Quad-City - Charlotte Douglas, Moline Quad-City - Charleston or Moline Quad-City - Myrtle Beach Intl when deciding on the best route from Moline to South Carolina.

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Moline to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to LaGuardia flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Las Vegas flights
O'Hare Intl to Newark flights
O'Hare Intl to Seattle flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Orlando flights
O'Hare Intl to Denver flights
O'Hare Intl to San Francisco flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Boston flights
O'Hare Intl to Miami flights
Midway to Las Vegas flights
O'Hare Intl to Dulles Intl flights
O'Hare Intl to Reagan-National flights
O'Hare Intl to Atlanta flights
O'Hare Intl to San Diego flights
O'Hare Intl to Baltimore flights
O'Hare Intl to Tampa flights
St. Louis to Las Vegas flights
Midway to Newark flights
O'Hare Intl to Honolulu flights
Midway to LaGuardia flights
O'Hare Intl to Ontario flights
O'Hare Intl to Nashville flights
O'Hare Intl to Santa Ana flights
Midway to John F Kennedy Intl flights
O'Hare Intl to Austin flights
O'Hare Intl to Portland flights
O'Hare Intl to Philadelphia flights
Midway to Atlanta flights
St. Louis to Seattle flights
Midway to Denver flights
O'Hare Intl to Fort Myers flights
O'Hare Intl to Hobby flights
O'Hare Intl to Salt Lake City flights
Midway to Orlando flights
Midway to Sky Harbor Intl flights
Midway to Miami flights
Midway to Hobby flights
St. Louis to LaGuardia flights
O'Hare Intl to Cleveland flights
Midway to Tampa flights
O'Hare Intl to Charleston flights
O'Hare Intl to George Bush Intcntl flights
O'Hare Intl to New Orleans flights
O'Hare Intl to Charlotte flights

Top 3 airlines flying from Moline to South Carolina

Discover the top 3 airlines that operate flights from Moline to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$349FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$221Average$433FlexibilityNo cancel feeOn-time69%
DeltaCheapest$236Average$342FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.