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South Carolina

$129+ Cheap flights from Moline (MLI) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — CHS
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Moline to South Carolina

Keep the following information in mind while searching for Moline to South Carolina flight deals. Data was last updated September 17, 2025.

Round-trip from

$249
(Delta)

One-way from

$129
(Delta)

Popular in

June

Cheapest in

February

Average price

$388
From Moline Quad-City to South Carolina
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One-way flight from Moline Quad-City to South Carolina
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Highest demand for flights based on searches. 2% potential increase in price ($9 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Moline to South Carolina

Cheapest flights from Moline to South Carolina
Explore the most affordable flight options available from Moline to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:00 amMLI - CHS
1 stop6h 25mDelta
Tue 10/214:14 pmCHS - MLI
1 stop7h 06mDelta
Deal found 9/17$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:17 amMLI - MYR
1 stop4h 18mAmerican Airlines
Mon 11/245:41 pmMYR - MLI
1 stop6h 33mAmerican Airlines
Deal found 9/15$249
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/215:00 pmMLI - SAV
1 stop5h 58mDelta
Sat 10/255:37 pmSAV - MLI
1 stop5h 43mDelta
Deal found 9/15$249
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:55 amMLI - HHH
1 stop5h 52mAmerican Airlines
Wed 12/177:08 pmHHH - MLI
1 stop4h 39mAmerican Airlines
Deal found 9/16$249
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:22 amMLI - GSP
1 stop4h 11mAmerican Airlines
Tue 11/46:12 amGSP - MLI
1 stop4h 08mAmerican Airlines
Deal found 9/15$249
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/186:30 amMLI - CHS
1 stop6h 37mUnited Airlines
Tue 10/2111:06 amCHS - MLI
2 stops10h 59mUnited Airlines
Deal found 9/17$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/175:00 pmMLI - SAV
1 stop4h 32mDelta
Thu 10/236:59 pmSAV - MLI
1 stop4h 21mDelta
Deal found 9/15$254
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:00 amMLI - CLT
1 stop6h 27mDelta
Sat 10/1811:41 amCLT - MLI
1 stop5h 39mDelta
Deal found 9/15$257
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/304:59 pmMLI - SAV
1 stop5h 56mDelta
Sat 10/411:40 amSAV - MLI
1 stop5h 39mDelta
Deal found 9/15$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amMLI - GSP
1 stop4h 16mUnited Airlines
Sat 10/45:34 pmGSP - MLI
1 stop6h 09mUnited Airlines
Deal found 9/15$259
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:30 amMLI - CHS
2 stops9h 10mUnited Airlines
Sat 10/44:15 pmCHS - MLI
1 stop5h 50mUnited Airlines
Deal found 9/15$264
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/304:59 pmMLI - MYR
1 stop5h 50mDelta
Sat 10/411:32 amMYR - MLI
2 stops12h 10mDelta
Deal found 9/14$264

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Moline to South Carolina that are best for you.

Fly from

Moline

Fly to

South Carolina

Route

Depart

Return

Price

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Sat 10/18

6:00 am-1:25 pm

1 stop6h 25m

Charleston

Tue 10/21

4:14 pm-10:20 pm

1 stop7h 06m

$249

MolineMyrtle Beach

MLI - MYR

MLIMYR

Moline Quad-City

Wed 11/19

5:22 pm-10:36 pm

1 stop4h 14m

Myrtle Beach Intl

Mon 11/24

5:41 pm-11:14 pm

1 stop6h 33m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Mon 10/20

6:30 am-12:09 pm

1 stop4h 39m

Savannah/Hilton Head

Sat 10/25

1:15 pm-4:54 pm

1 stop4h 39m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Tue 10/21

5:00 pm-11:58 pm

1 stop5h 58m

Savannah/Hilton Head

Sat 10/25

5:37 pm-10:20 pm

1 stop5h 43m

$249

MolineHilton Head Island

MLI - HHH

MLIHHH

Moline Quad-City

Sat 12/13

6:55 am-1:47 pm

1 stop5h 52m

Hilton Head Island

Wed 12/17

7:08 pm-10:47 pm

1 stop4h 39m

$249

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Fri 10/17

5:00 pm-11:58 pm

1 stop5h 58m

Savannah/Hilton Head

Thu 10/23

5:37 pm-10:20 pm

1 stop5h 43m

$249

MolineGreenville

MLI - GSP

MLIGSP

Moline Quad-City

Sat 11/1

11:22 am-4:33 pm

1 stop4h 11m

Greenville

Tue 11/4

6:12 am-9:20 am

1 stop4h 08m

$249

MolineColumbia

MLI - CAE

MLICAE

Moline Quad-City

Sat 2/21

5:00 pm-11:54 pm

1 stop5h 54m

Columbia Metropolitan

Tue 2/24

5:10 pm-10:34 pm

1 stop6h 24m

$249

MolineCharleston

MLI - CHS

MLICHS

Moline Quad-City

Sat 10/18

6:30 am-2:07 pm

1 stop6h 37m

Charleston

Tue 10/21

11:06 am-9:05 pm

2 stops10h 59m

$254

MolineSavannah

MLI - SAV

MLISAV

Moline Quad-City

Tue 10/21

6:00 am-11:29 am

1 stop4h 29m

Savannah/Hilton Head

Sat 10/25

8:59 am-6:02 pm

2 stops10h 03m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 58 results
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Best time to book a flight from Moline to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South Carolina

What is the cheapest month to book a flight from Moline to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 17, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Moline to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Moline to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South Carolina?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to South Carolina. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • How long is the flight from Moline to South Carolina?

    There are many flights that can get you from Moline to South Carolina in 4h 14m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. Airlines will cover a distance of 829 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Moline to South Carolina one-way?

    One-way options have recently been found by users for as low as $129 on Delta. Other airlines that offer cheap prices include Allegiant Air from $215 and United Airlines from $244 one-way.

  • What are the most popular routes from Moline to South Carolina?

    Most travelers choose Moline Quad-City - Charlotte Douglas, Moline Quad-City - Myrtle Beach Intl or Moline Quad-City - Charleston when deciding on the best route from Moline to South Carolina.

  • Can I find deals for flights from Moline to South Carolina that include hotel bookings?

    Yes. In addition to deals on Moline to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South Carolina.

  • Can I find deals for business class flights from Moline to South Carolina?

    Yes. Cheapflights offers flight deals from Moline to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Moline to South Carolina (average of $217). Flying from Moline to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Moline to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Moline to South Carolina

Discover the top 3 airlines that operate flights from Moline to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$352FlexibilityNo cancel feeOn-time71%
DeltaCheapest$208Average$338FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$221Average$362FlexibilityNo cancel feeOn-time69%

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