$108+ Cheap flights from Minneapolis (MSP) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Aug 26 — Sep 21
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minneapolis to South Carolina
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Cheapest flights from Minneapolis to South CarolinaExplore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.
This Sun Country Air deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:50 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Thu 8/208:30 am
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$218
This Super.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:25 am
MSP
- CLT
Nonstop2h 33m
Sun Country Air
Sun 10/188:30 am
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 7/26![Sun Country Air logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:00 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Sun 10/44:16 pm
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 7/26![Sun Country Air logo]()
$227
This Sun Country Air deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/112:20 pm
MSP
- CLT
Nonstop2h 33m
Sun Country Air
Sun 10/188:30 am
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 7/24![Sun Country Air logo]()
$228
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:13 pm
MSP
- CLT
1 stop7h 06m
Multiple Airlines
Thu 8/208:30 am
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$234
This Expedia deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:35 am
MSP
- CLT
Nonstop2h 33m
Multiple Airlines
Tue 9/2212:05 pm
CLT
- MSP
1 stop6h 56m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$236
This Cheapflightsfares deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Mon 8/105:35 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$237
This Priceline deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:58 am
MSP
- CLT
1 stop6h 48m
Multiple Airlines
Sun 9/138:30 am
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$239
This Frontier deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:53 am
MSP
- CLT
1 stop7h 58m
Frontier
Wed 10/2111:44 am
CLT
- MSP
1 stop6h 18m
Frontier
Deal found 7/22![Frontier logo]()
$240
This Orbitz deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:58 am
MSP
- CLT
1 stop6h 48m
Multiple Airlines
Thu 10/812:18 pm
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$241
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:13 pm
MSP
- CLT
1 stop7h 06m
Multiple Airlines
Mon 8/176:25 pm
CLT
- MSP
Nonstop2h 43m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$242
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:45 pm
MSP
- SAV
Nonstop2h 44m
Delta
Tue 11/175:11 pm
SAV
- MSP
Nonstop3h 04m
Delta
Deal found 7/22![Delta logo]()
$249
Best flights from Minneapolis to South CarolinaDiscover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
Discover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 27, 2026.
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:45 am
MSP
- GSP
2 stops5h 45m
Southwest
Wed 9/165:30 pm
GSP
- MSP
1 stop6h 20m
Southwest
Deal found 7/22![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:21 pm
MSP
- GSP
1 stop4h 46m
United Airlines
Sun 9/67:00 am
GSP
- MSP
2 stops8h 19m
United Airlines
Deal found 7/22![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:45 pm
MSP
- CHS
Nonstop2h 49m
Delta
Wed 9/307:10 am
CHS
- MSP
1 stop7h 19m
Delta
Deal found 7/26![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:25 am
MSP
- HHH
1 stop5h 25m
American Airlines
Wed 9/162:15 pm
HHH
- MSP
1 stop7h 48m
American Airlines
Deal found 7/22![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:25 pm
MSP
- GSP
2 stops7h 35m
Southwest
Mon 9/284:40 pm
GSP
- MSP
1 stop6h 30m
Southwest
Deal found 7/25![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
MSP
- GSP
2 stops8h 45m
Southwest
Tue 9/18:15 am
GSP
- MSP
1 stop6h 20m
Southwest
Deal found 7/26![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
MSP
- CAE
1 stop6h 40m
United Airlines
Sat 9/122:15 pm
CAE
- MSP
1 stop6h 50m
United Airlines
Deal found 7/24![United Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:50 pm
MSP
- CHS
Nonstop2h 49m
Delta
Tue 9/295:25 am
CHS
- MSP
1 stop4h 39m
Delta
Deal found 7/26![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:25 pm
MSP
- GSP
2 stops7h 35m
Southwest
Tue 9/291:20 pm
GSP
- MSP
1 stop5h 50m
Southwest
Deal found 7/26![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/243:15 pm
MSP
- CHS
1 stop5h 31m
Delta
Fri 1/16:55 pm
CHS
- MSP
Nonstop3h 15m
Delta
Deal found 7/22![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:10 am
MSP
- HHH
1 stop7h 47m
American Airlines
Fri 8/285:16 pm
HHH
- MSP
1 stop4h 50m
American Airlines
Deal found 7/25![American Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:19 am
MSP
- CAE
1 stop4h 37m
United Airlines
Tue 10/1310:23 am
CAE
- MSP
2 stops10h 39m
United Airlines
Deal found 7/25![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:28 am
MSP
- CHS
Nonstop2h 48m
Delta
Wed 10/216:30 am
CHS
- MSP
1 stop4h 49m
Delta
Deal found 7/26![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:46 pm
MSP
- HHH
2 stops15h 29m
American Airlines
Mon 9/145:15 pm
HHH
- MSP
1 stop4h 48m
American Airlines
Deal found 7/22![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:21 pm
MSP
- CAE
1 stop5h 07m
United Airlines
Mon 8/3110:22 am
CAE
- MSP
2 stops11h 11m
United Airlines
Deal found 7/26![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:25 am
MSP
- SAV
1 stop7h 08m
Delta
Tue 10/135:24 pm
SAV
- MSP
Nonstop3h 07m
Delta
Deal found 7/23![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:15 pm
MSP
- GSP
1 stop5h 30m
Southwest
Wed 10/211:25 pm
GSP
- MSP
2 stops9h 40m
Southwest
Deal found 7/25![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:32 am
MSP
- CAE
2 stops7h 35m
United Airlines
Sun 8/306:25 am
CAE
- MSP
1 stop5h 00m
United Airlines
Deal found 7/22![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:30 pm
MSP
- SAV
1 stop4h 51m
Delta
Fri 8/285:18 pm
SAV
- MSP
Nonstop2h 57m
Delta
Deal found 7/22![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2611:08 am
MSP
- AGS
1 stop6h 35m
American Airlines
Sat 10/37:45 am
AGS
- MSP
1 stop7h 29m
American Airlines
Deal found 7/25![American Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:15 pm
MSP
- SAV
1 stop7h 35m
Southwest
Mon 9/215:35 pm
SAV
- MSP
1 stop5h 35m
Southwest
Deal found 7/23![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:12 pm
MSP
- CHS
1 stop7h 29m
United Airlines
Mon 11/235:00 pm
CHS
- MSP
1 stop6h 04m
United Airlines
Deal found 7/26![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 pm
MSP
- SAV
1 stop4h 51m
Delta
Fri 9/45:18 pm
SAV
- MSP
Nonstop2h 57m
Delta
Deal found 7/26![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:25 pm
MSP
- CHS
1 stop4h 50m
Southwest
Mon 12/146:35 am
CHS
- MSP
1 stop4h 45m
Southwest
Deal found 7/24![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:19 am
MSP
- HHH
1 stop6h 57m
American Airlines
Wed 8/1211:40 am
HHH
- MSP
2 stops13h 44m
American Airlines
Deal found 7/22![American Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:00 am
MSP
- CAE
2 stops10h 07m
United Airlines
Mon 9/76:25 am
CAE
- MSP
1 stop5h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:55 pm
MSP
- CLT
Nonstop2h 32m
Delta
Tue 9/85:13 pm
CLT
- MSP
Nonstop2h 45m
Delta
Deal found 7/25![Delta logo]()
$325
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1912:25 pm
MSP
- MYR
2 stops5h 55m
Southwest
Wed 8/262:25 pm
MYR
- MSP
2 stops9h 25m
Southwest
Deal found 7/22![Southwest logo]()
$329
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:20 pm
MSP
- CHS
1 stop4h 39m
Delta
Thu 11/266:00 am
CHS
- MSP
1 stop5h 26m
Delta
Deal found 7/25![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
MSP
- MYR
2 stops8h 40m
Southwest
Sat 10/31:10 pm
MYR
- MSP
1 stop10h 00m
Southwest
Deal found 7/23![Southwest logo]()
$330
Last-minute flights from Minneapolis to South CarolinaDiscover last-minute flight deals from Minneapolis to South Carolina. Data last updated July 27, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to South Carolina. Data last updated July 27, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Mon 8/105:35 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$237
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:50 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Mon 8/176:25 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 7/23![Sun Country Air logo]()
$238
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:13 pm
MSP
- CLT
1 stop7h 06m
Multiple Airlines
Thu 8/208:30 am
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$234
This Travelocity deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:13 pm
MSP
- CLT
1 stop7h 06m
Frontier
Thu 8/202:45 pm
CLT
- MSP
1 stop28h 47m
Frontier
Deal found 7/22![Frontier logo]()
$240
This CheapOair deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:13 pm
MSP
- CLT
1 stop7h 06m
Multiple Airlines
Mon 8/176:25 pm
CLT
- MSP
Nonstop2h 43m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
MSP
- GSP
1 stop5h 15m
Southwest
Sat 8/2212:55 pm
GSP
- MSP
1 stop6h 50m
Southwest
Deal found 7/24![Southwest logo]()
$259
This Sun Country Air deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:50 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Thu 8/208:30 am
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$218
This Trip.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:17 pm
MSP
- CLT
1 stop11h 44m
Multiple Airlines
Mon 11/236:56 pm
CLT
- MSP
Nonstop2h 49m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
MSP
- GSP
2 stops8h 45m
Southwest
Tue 9/18:15 am
GSP
- MSP
1 stop6h 20m
Southwest
Deal found 7/26![Southwest logo]()
$264
This Expedia deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:17 pm
MSP
- CLT
1 stop11h 44m
Multiple Airlines
Sun 8/308:00 am
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 7/22![Multiple Airlines logo]()
$245
This Frontier deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:17 pm
MSP
- CLT
1 stop11h 44m
Frontier
Sun 8/309:06 pm
CLT
- MSP
1 stop12h 57m
Frontier
Deal found 7/22![Frontier logo]()
$248
This CheapOair deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:17 pm
MSP
- CLT
1 stop17h 33m
Frontier
Mon 8/315:21 pm
CLT
- MSP
1 stop20h 45m
Frontier
Deal found 7/23![Frontier logo]()
$251
One-way flights from Minneapolis to South CarolinaSearch for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
Search for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 27, 2026.
This Super.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Deal found 7/23![Sun Country Air logo]()
$108
This Sun Country Air deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:30 am
MSP
- CLT
Nonstop2h 33m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$109
This Super.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:30 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Deal found 7/22![Sun Country Air logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:17 pm
MSP
- CHS
1 stop12h 21m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$120
This Frontier deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:58 am
MSP
- CLT
1 stop6h 48m
Frontier
Deal found 7/22![Frontier logo]()
$120
This Super.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:17 pm
MSP
- CLT
1 stop20h 41m
Frontier
Deal found 7/23![Frontier logo]()
$125
This Frontier deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:17 pm
MSP
- CLT
1 stop11h 44m
Frontier
Deal found 7/23![Frontier logo]()
$126
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:17 pm
MSP
- GSP
1 stop7h 08m
American Airlines
Deal found 7/24![American Airlines logo]()
$130
This CheapOair deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:30 pm
MSP
- CLT
1 stop19h 16m
Frontier
Deal found 7/23![Frontier logo]()
$131
This Trip.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/252:01 pm
MSP
- CLT
1 stop25h 25m
Frontier
Deal found 7/26![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:17 pm
MSP
- CHS
1 stop12h 31m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$133
This Frontier deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:53 am
MSP
- CLT
1 stop7h 58m
Frontier
Deal found 7/26![Frontier logo]()
$133
Find flight deals from Minneapolis to South Carolina
Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated July 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $218 (Sun Country Air) |
One-way from | $108 (Super.com) |
Popular in | March |
Cheapest in | February |
Average price | $374 |
Good round-trip deal | $167 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisGreenville
MSP - GSP
MSPGSP
Minneapolis St Paul
Thu 9/10
5:45 am-12:30 pm
2 stops5h 45m
Greenville
Wed 9/16
5:30 pm-10:50 pm
1 stop6h 20m
$264
MinneapolisGreenville
MSP - GSP
MSPGSP
Minneapolis St Paul
Wed 9/23
12:25 pm-9:00 pm
2 stops7h 35m
Greenville
Mon 9/28
4:40 pm-10:10 pm
1 stop6h 30m
$264
MinneapolisGreenville
MSP - GSP
MSPGSP
Minneapolis St Paul
Tue 8/25
7:00 am-4:45 pm
2 stops8h 45m
Greenville
Tue 9/1
8:15 am-1:35 pm
1 stop6h 20m
$264
MinneapolisGreenville
MSP - GSP
MSPGSP
Minneapolis St Paul
Wed 9/23
12:25 pm-9:00 pm
2 stops7h 35m
Greenville
Tue 9/29
1:20 pm-6:10 pm
1 stop5h 50m
$264
MinneapolisGreenville
MSP - GSP
MSPGSP
Minneapolis St Paul
Sat 9/5
3:21 pm-9:07 pm
1 stop4h 46m
Greenville
Sun 9/6
7:00 am-2:19 pm
2 stops8h 19m
$269
MinneapolisColumbia
MSP - CAE
MSPCAE
Minneapolis St Paul
Wed 9/9
6:00 am-1:40 pm
1 stop6h 40m
Columbia Metropolitan
Sat 9/12
2:15 pm-8:05 pm
1 stop6h 50m
$315
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Tue 9/22
12:45 pm-4:34 pm
Nonstop2h 49m
Charleston
Wed 9/30
7:10 am-1:29 pm
1 stop7h 19m
$319
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Sat 9/26
12:50 pm-4:39 pm
Nonstop2h 49m
Charleston
Tue 9/29
5:25 am-9:04 am
1 stop4h 39m
$319
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Thu 12/24
3:15 pm-9:46 pm
1 stop5h 31m
Charleston
Fri 1/1
6:55 pm-9:10 pm
Nonstop3h 15m
$319
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Fri 10/16
10:28 am-2:16 pm
Nonstop2h 48m
Charleston
Wed 10/21
6:30 am-10:19 am
1 stop4h 49m
$319
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
MSP-CLT
MSP-GSP
MSP-HHH
MSP-CHS
MSP-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South Carolina
MSP-USSC
MSP-CLT
MSP-GSP
MSP-HHH
MSP-CHS
What is the cheapest month to book a flight from Minneapolis to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $325). Flying from Minneapolis to South Carolina in March is currently the most expensive (average of $430). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to SC?
Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 27, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to South Carolina as you normally would.
How much does it cost to fly round-trip from Minneapolis to South Carolina?
Airfare is below average for this route at the moment.
Minneapolis to South Carolina flights typically cost between $319 and $528 in November.The cheapest round-trip price found within the last 5 days was $259 on Delta (Nov 14-Nov 18).
How far ahead should I book a flight from Minneapolis to South Carolina?
The price you pay for your flight from Minneapolis to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 27, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Boarding
8.1
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Minneapolis to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and South Carolina flights
Browse other Minneapolis and South Carolina flight options. Last updated on July 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Minneapolis to South Carolina flights
Consider these flights traveling from Minneapolis to South Carolina.
Top 5 airlines flying from Minneapolis to South Carolina
Discover the top 5 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$261 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$198 | Average$399 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$469 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$237 | Average$394 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$250 | Average$416 | FlexibilityNo cancel fee | On-time71% |