$117+ Cheap flights from Minneapolis (MSP) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Minneapolis to South CarolinaExplore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:23 am -
1 stop4h 43m
Mon 12/76:47 pm -
1 stop6h 39m
Deal found 10/28![American Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:50 am -
2 stops9h 20m
Sat 12/127:05 am -
1 stop4h 25m
Deal found 10/29![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:28 pm -
1 stop4h 25m
Tue 11/245:40 am -
1 stop4h 23m
Deal found 10/28![Delta logo]()
$253
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:55 am -
2 stops8h 55m
Wed 12/96:45 pm -
1 stop5h 15m
Deal found 10/29![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:22 am -
Nonstop2h 55m
Wed 12/163:14 pm -
Nonstop3h 11m
Deal found 10/26![Delta logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:31 pm -
2 stops16h 07m
Tue 12/153:00 pm -
1 stop24h 06m
Deal found 10/25![Multiple Airlines logo]()
$266
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:24 am -
1 stop5h 26m
Tue 12/83:14 pm -
Nonstop3h 11m
Deal found 10/29![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:12 pm -
1 stop7h 09m
Sat 12/126:00 am -
1 stop5h 44m
Deal found 10/26![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:24 am -
1 stop4h 49m
Sun 12/65:40 am -
1 stop5h 37m
Deal found 10/28![Delta logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:42 pm -
2 stops21h 23m
Tue 12/153:00 pm -
1 stop24h 06m
Deal found 10/25![Multiple Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:40 pm -
1 stop4h 45m
Tue 12/296:35 am -
1 stop4h 30m
Deal found 10/27![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:22 am -
Nonstop2h 55m
Sun 12/65:10 am -
1 stop6h 07m
Deal found 10/26![Delta logo]()
$289
Best flights from Minneapolis to South CarolinaDiscover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/71:18 pm -
Nonstop2h 47m
Tue 1/129:47 am -
1 stop6h 38m
Deal found 10/29![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:12 pm -
1 stop7h 09m
Wed 12/166:00 am -
1 stop5h 27m
Deal found 10/26![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2111:10 am -
2 stops7h 25m
Sat 1/237:00 am -
2 stops6h 10m
Deal found 10/29![Southwest logo]()
$289
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:23 am -
1 stop4h 43m
Sun 12/67:05 am -
1 stop7h 42m
Deal found 10/25![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:12 pm -
1 stop7h 09m
Sat 12/126:00 am -
1 stop5h 44m
Deal found 10/26![United Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2512:45 pm -
1 stop4h 11m
Fri 1/17:21 am -
1 stop7h 11m
Deal found 10/28![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
2 stops7h 22m
Sat 1/235:29 pm -
1 stop4h 59m
Deal found 10/29![United Airlines logo]()
$284
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/92:13 pm -
Nonstop2h 52m
Tue 1/129:47 am -
1 stop6h 38m
Deal found 10/29![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/510:35 am -
2 stops8h 55m
Mon 2/89:10 pm -
1 stop4h 35m
Deal found 10/27![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/211:15 pm -
Nonstop2h 47m
Sun 1/245:57 pm -
Nonstop3h 13m
Deal found 10/25![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:28 pm -
1 stop4h 54m
Sun 12/65:40 am -
1 stop5h 37m
Deal found 10/28![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:50 am -
2 stops8h 35m
Sun 12/66:35 am -
2 stops8h 35m
Deal found 10/28![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:45 am -
2 stops8h 39m
Sat 1/2310:05 am -
1 stop5h 28m
Deal found 10/29![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/161:17 pm -
2 stops21h 43m
Tue 1/194:25 pm -
2 stops17h 08m
Deal found 10/27![American Airlines logo]()
$455
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:50 am -
2 stops9h 20m
Mon 12/72:50 pm -
2 stops9h 10m
Deal found 10/28![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:22 am -
Nonstop2h 55m
Sun 12/207:05 pm -
Nonstop3h 10m
Deal found 10/25![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1511:32 am -
2 stops11h 10m
Sat 4/175:25 pm -
1 stop4h 51m
Deal found 10/27![United Airlines logo]()
$354
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/249:45 am -
2 stops8h 39m
Sun 1/316:15 am -
1 stop5h 03m
Deal found 10/26![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:00 am -
2 stops8h 10m
Sun 12/66:40 am -
2 stops8h 30m
Deal found 10/25![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:05 am -
1 stop7h 05m
Sun 12/205:09 am -
1 stop5h 04m
Deal found 10/30![American Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:24 am -
1 stop4h 49m
Sun 12/65:40 am -
1 stop5h 37m
Deal found 10/26![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:15 am -
1 stop5h 45m
Fri 12/48:10 am -
1 stop7h 40m
Deal found 10/28![Southwest logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:10 am -
1 stop7h 11m
Tue 11/174:17 pm -
1 stop6h 27m
Deal found 10/29![American Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:25 am -
1 stop6h 24m
Mon 1/112:34 pm -
1 stop5h 39m
Deal found 10/28![Delta logo]()
$349
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:43 am -
1 stop6h 17m
Mon 11/165:37 pm -
1 stop6h 22m
Deal found 10/29![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
2 stops6h 15m
Thu 12/31:30 pm -
2 stops9h 25m
Deal found 10/29![Southwest logo]()
$415
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/136:18 am -
1 stop7h 10m
Thu 3/187:10 pm -
1 stop5h 20m
Deal found 10/25![American Airlines logo]()
$543
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:24 am -
1 stop4h 44m
Thu 11/195:35 am -
1 stop7h 10m
Deal found 10/26![Delta logo]()
$374
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/266:45 pm -
1 stop3h 55m
Wed 12/306:45 am -
1 stop4h 20m
Deal found 10/28![Southwest logo]()
$423
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/211:11 pm -
2 stops9h 48m
Sun 1/246:00 am -
2 stops9h 19m
Deal found 10/25![United Airlines logo]()
$439
Last-minute flights from Minneapolis to South CarolinaDiscover last-minute flight deals from Minneapolis to South Carolina. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to South Carolina. Data last updated October 30, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:28 pm -
1 stop4h 25m
Tue 11/245:40 am -
1 stop4h 23m
Deal found 10/28![Delta logo]()
$253
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:45 pm -
1 stop6h 16m
Wed 11/252:00 pm -
1 stop6h 15m
Deal found 10/28![Delta logo]()
$276
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:35 pm -
1 stop5h 19m
Wed 11/256:27 pm -
1 stop6h 38m
Deal found 10/26![American Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:30 pm -
1 stop7h 06m
Tue 12/11:21 pm -
2 stops26h 24m
Deal found 10/27![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/222:30 pm -
1 stop7h 06m
Wed 12/26:40 am -
2 stops33h 05m
Deal found 10/27![Multiple Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:05 am -
1 stop5h 10m
Tue 11/245:40 am -
1 stop4h 23m
Deal found 10/28![Delta logo]()
$233
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop7h 58m
Fri 11/277:01 am -
1 stop5h 35m
Deal found 10/28![American Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop15h 31m
Thu 11/2611:36 am -
1 stop24h 15m
Deal found 10/27![American Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:42 pm -
1 stop19h 01m
Tue 12/11:21 pm -
2 stops26h 24m
Deal found 10/27![Multiple Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:42 pm -
1 stop19h 01m
Wed 12/26:40 am -
2 stops33h 05m
Deal found 10/27![Multiple Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:27 pm -
1 stop5h 33m
Wed 12/26:47 pm -
1 stop5h 48m
Deal found 10/29![American Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop11h 45m
Thu 12/36:25 pm -
1 stop5h 35m
Deal found 10/27![Southwest logo]()
$326
One-way flights from Minneapolis to South CarolinaSearch for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop5h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/73:31 pm -
2 stops22h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$137
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:15 am -
1 stop4h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Delta logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:31 pm -
2 stops15h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:11 am -
3 stops49h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:42 pm -
2 stops19h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/25![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:42 pm -
3 stops39h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$147
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:45 am -
1 stop7h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Southwest logo]()
$160
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:15 pm -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Southwest logo]()
$160
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:18 am -
1 stop5h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![American Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/310:15 am -
2 stops26h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![Multiple Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:05 am -
1 stop5h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/28![American Airlines logo]()
$175
Find flight deals from Minneapolis to South Carolina
Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated October 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $198 (Booking.com) |
One-way from | $117 (Delta) |
Popular in | October |
Cheapest in | May |
Average price | $469 |
Good round-trip deal | $349 or less |
Good one-way deal | $223 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Mon 12/7
5:24 am-11:13 am
1 stop4h 49m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Mon 12/7
3:31 pm-3:29 pm
2 stops22h 58m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$137
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Mon 1/4
5:15 am-11:06 am
1 stop4h 51m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$140
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Sun 12/6
3:31 pm-8:13 am
2 stops15h 42m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$143
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Sat 12/5
3:42 pm-12:14 pm
2 stops19h 32m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$145
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Sat 12/5
3:42 pm-8:13 am
3 stops39h 31m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$147
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Sun 12/6
5:15 pm-11:00 pm
1 stop4h 45m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$160
Quickest round-trip
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Sun 12/6
6:28 pm-11:47 pm
1 stop4h 19m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$160
MinneapolisCharleston
MSP Minneapolis St Paul - CHS Charleston
MSPCHS
Minneapolis St Paul
Fri 1/15
10:35 am-6:20 pm
2 stops6h 45m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Sat 12/5
11:03 am-4:38 pm
1 stop4h 35m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$175
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
MSP-GSP
MSP-MYR
MSP-CHS
MSP-HHH
MSP-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South Carolina
MSP-USSC
MSP-GSP
MSP-MYR
MSP-CHS
MSP-HHH
What is the cheapest month to book a flight from Minneapolis to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $326). Flying from Minneapolis to South Carolina in October is currently the most expensive (average of $442). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to SC?
Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to South Carolina as you normally would.
How much does it cost to fly round-trip from Minneapolis to South Carolina?
Airfare is below average for this route at the moment.
Minneapolis to South Carolina flights typically cost between $339 and $517 in April.The cheapest round-trip price found within the last 5 days was $198 on Sun Country Air (Apr 10-Apr 12).
How far ahead should I book a flight from Minneapolis to South Carolina?
The price you pay for your flight from Minneapolis to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 74 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Overall
7.9
Comfort
8.0
Boarding
8.1
Entertainment
7.4
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Minneapolis to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and South Carolina flights
Browse other Minneapolis and South Carolina flight options. Last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Minneapolis to South Carolina flights
Consider these flights traveling from Minneapolis to South Carolina.
Top 5 airlines flying from Minneapolis to South Carolina
Discover the top 5 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$259 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$205 | Average$414 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$237 | Average$407 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$264 | Average$434 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$264 | Average$478 | FlexibilityNo cancel fee | On-time69% |