$78+ Cheap flights from Minneapolis (MSP) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/25. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Cheapest flights from Minneapolis to South CarolinaExplore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:55 pm
MSP
- MYR
1 stop4h 25m
Southwest
Wed 8/196:30 pm
MYR
- MSP
1 stop5h 20m
Southwest
Deal found 6/8![Southwest logo]()
$212
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:15 am
MSP
- SAV
1 stop4h 15m
Southwest
Tue 9/226:35 pm
SAV
- MSP
1 stop5h 15m
Southwest
Deal found 6/8![Southwest logo]()
$212
This Super.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:40 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Wed 7/158:15 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/9![Sun Country Air logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:40 am
MSP
- CLT
Nonstop2h 33m
Sun Country Air
Sun 10/116:53 pm
CLT
- MSP
Nonstop2h 45m
Sun Country Air
Deal found 6/9![Sun Country Air logo]()
$227
This Sun Country Air deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:20 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Mon 8/36:25 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$228
This Orbitz deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:58 am
MSP
- CLT
1 stop6h 48m
Multiple Airlines
Sun 9/138:30 am
CLT
- MSP
Nonstop2h 45m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$229
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am
MSP
- CHS
1 stop4h 45m
Southwest
Tue 12/87:55 am
CHS
- MSP
1 stop4h 50m
Southwest
Deal found 6/8![Southwest logo]()
$230
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:55 pm
MSP
- CHS
1 stop4h 50m
Southwest
Mon 8/176:30 pm
CHS
- MSP
1 stop4h 40m
Southwest
Deal found 6/8![Southwest logo]()
$232
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/191:55 pm
MSP
- MYR
1 stop4h 25m
Southwest
Sat 8/224:20 pm
MYR
- MSP
1 stop4h 45m
Southwest
Deal found 6/8![Southwest logo]()
$232
This Super.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Fri 7/246:33 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/7![Sun Country Air logo]()
$236
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:40 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Mon 7/136:25 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$237
This Sun Country Air deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Fri 7/101:15 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$238
Best flights from Minneapolis to South CarolinaDiscover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:40 am
MSP
- CHS
2 stops8h 45m
Southwest
Sat 10/316:40 am
CHS
- MSP
2 stops8h 35m
Southwest
Deal found 6/8![Southwest logo]()
$265
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:32 am
MSP
- CHS
Nonstop2h 45m
Delta
Tue 9/83:10 pm
CHS
- MSP
Nonstop3h 05m
Delta
Deal found 6/9![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
MSP
- HHH
1 stop7h 21m
United Airlines
Wed 8/122:48 pm
HHH
- MSP
1 stop8h 04m
United Airlines
Deal found 6/5![United Airlines logo]()
$301
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:10 am
MSP
- CAE
1 stop7h 17m
American Airlines
Mon 9/76:15 am
CAE
- MSP
1 stop5h 07m
American Airlines
Deal found 6/9![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:32 am
MSP
- CHS
Nonstop2h 45m
Delta
Sun 9/63:14 pm
CHS
- MSP
Nonstop3h 00m
Delta
Deal found 6/7![Delta logo]()
$284
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:55 am
MSP
- MYR
2 stops8h 40m
Southwest
Thu 8/273:20 pm
MYR
- MSP
2 stops7h 00m
Southwest
Deal found 6/8![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:00 am
MSP
- HHH
1 stop5h 03m
United Airlines
Mon 8/242:48 pm
HHH
- MSP
1 stop8h 04m
United Airlines
Deal found 6/7![United Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:04 am
MSP
- CHS
1 stop5h 13m
Delta
Sun 8/233:14 pm
CHS
- MSP
Nonstop3h 00m
Delta
Deal found 6/6![Delta logo]()
$294
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:10 am
MSP
- GSP
1 stop4h 20m
Southwest
Thu 8/204:40 pm
GSP
- MSP
1 stop6h 25m
Southwest
Deal found 6/9![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:25 pm
MSP
- SAV
1 stop5h 07m
Delta
Sat 10/315:11 pm
SAV
- MSP
Nonstop3h 04m
Delta
Deal found 6/8![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:25 am
MSP
- AGS
1 stop4h 56m
American Airlines
Sat 10/33:59 pm
AGS
- MSP
1 stop7h 54m
American Airlines
Deal found 6/5![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:05 am
MSP
- MYR
2 stops9h 55m
Southwest
Sat 8/2211:55 am
MYR
- MSP
1 stop5h 15m
Southwest
Deal found 6/9![Southwest logo]()
$321
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
MSP
- CAE
2 stops7h 21m
United Airlines
Sat 9/192:15 pm
CAE
- MSP
1 stop6h 50m
United Airlines
Deal found 6/9![United Airlines logo]()
$364
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:00 am
MSP
- SAV
1 stop7h 30m
Delta
Sun 8/235:35 am
SAV
- MSP
1 stop4h 25m
Delta
Deal found 6/5![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:40 am
MSP
- SAV
2 stops8h 15m
Southwest
Mon 9/144:10 pm
SAV
- MSP
2 stops7h 00m
Southwest
Deal found 6/9![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:00 am
MSP
- CAE
2 stops7h 21m
United Airlines
Sun 8/306:25 am
CAE
- MSP
1 stop6h 40m
United Airlines
Deal found 6/9![United Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:00 am
MSP
- HHH
1 stop7h 19m
Delta
Sat 10/244:00 pm
HHH
- MSP
1 stop6h 15m
Delta
Deal found 6/9![Delta logo]()
$310
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:17 am
MSP
- HHH
1 stop6h 15m
American Airlines
Thu 10/2211:16 am
HHH
- MSP
1 stop7h 07m
American Airlines
Deal found 6/5![American Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:55 am
MSP
- GSP
2 stops8h 45m
Southwest
Fri 11/68:50 pm
GSP
- MSP
1 stop4h 50m
Southwest
Deal found 6/8![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
MSP
- CAE
2 stops7h 21m
United Airlines
Mon 9/76:25 am
CAE
- MSP
1 stop6h 40m
United Airlines
Deal found 6/5![United Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:32 am
MSP
- CHS
Nonstop2h 45m
Delta
Sun 8/235:10 am
CHS
- MSP
1 stop4h 50m
Delta
Deal found 6/5![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/217:55 am
MSP
- MYR
1 stop4h 15m
Southwest
Tue 8/256:30 pm
MYR
- MSP
1 stop5h 20m
Southwest
Deal found 6/6![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:10 am
MSP
- AGS
2 stops10h 56m
American Airlines
Fri 7/104:00 pm
AGS
- MSP
1 stop8h 57m
American Airlines
Deal found 6/6![American Airlines logo]()
$460
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/253:56 pm
MSP
- CHS
1 stop5h 17m
Delta
Mon 9/285:25 am
CHS
- MSP
1 stop4h 39m
Delta
Deal found 6/9![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
MSP
- HHH
1 stop7h 03m
United Airlines
Wed 9/22:48 pm
HHH
- MSP
1 stop6h 15m
United Airlines
Deal found 6/9![United Airlines logo]()
$395
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:45 am
MSP
- MYR
2 stops6h 25m
Southwest
Mon 9/141:55 pm
MYR
- MSP
2 stops9h 15m
Southwest
Deal found 6/9![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:09 pm
MSP
- CAE
1 stop6h 37m
Delta
Sun 7/55:35 am
CAE
- MSP
1 stop4h 25m
Delta
Deal found 6/8![Delta logo]()
$322
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/69:59 am
MSP
- FLO
1 stop7h 08m
American Airlines
Tue 11/1011:11 am
FLO
- MSP
2 stops12h 51m
American Airlines
Deal found 6/5![American Airlines logo]()
$475
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
MSP
- GSP
1 stop6h 32m
United Airlines
Mon 8/244:33 pm
GSP
- MSP
1 stop8h 25m
United Airlines
Deal found 6/9![United Airlines logo]()
$397
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:15 pm
MSP
- MYR
1 stop6h 25m
Southwest
Wed 8/122:25 pm
MYR
- MSP
2 stops9h 25m
Southwest
Deal found 6/5![Southwest logo]()
$334
Last-minute flights from Minneapolis to South CarolinaDiscover last-minute flight deals from Minneapolis to South Carolina. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to South Carolina. Data last updated June 10, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:45 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Fri 6/198:43 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/5![Sun Country Air logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/288:20 am
MSP
- CHS
Nonstop2h 41m
Multiple Airlines
Sat 7/46:00 am
CHS
- MSP
1 stop9h 15m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$255
This Priceline deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:18 am
MSP
- CLT
1 stop7h 01m
Frontier
Sat 7/46:00 am
CLT
- MSP
1 stop11h 04m
Frontier
Deal found 6/9![Frontier logo]()
$244
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:15 pm
MSP
- CLT
1 stop22h 10m
Frontier
Fri 7/310:14 pm
CLT
- MSP
1 stop24h 16m
Frontier
Deal found 6/9![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:15 pm
MSP
- CLT
1 stop19h 04m
Frontier
Sat 7/46:00 am
CLT
- MSP
1 stop11h 04m
Frontier
Deal found 6/8![Frontier logo]()
$254
This Cheapflightsfares deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:50 am
MSP
- CLT
Nonstop2h 39m
Sun Country Air
Mon 7/66:45 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/9![Sun Country Air logo]()
$247
This Super.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Fri 7/246:33 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/7![Sun Country Air logo]()
$236
This Sun Country Air deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:10 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Fri 7/101:15 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$238
This Super.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:40 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Wed 7/158:15 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/9![Sun Country Air logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:40 am
MSP
- CLT
Nonstop2h 36m
Sun Country Air
Mon 7/136:25 pm
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$237
This Sun Country Air deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:20 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Sun 8/27:30 am
CLT
- MSP
Nonstop2h 43m
Sun Country Air
Deal found 6/10![Sun Country Air logo]()
$228
This Expedia deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:15 pm
MSP
- CLT
1 stop22h 04m
Multiple Airlines
Mon 7/205:50 pm
CLT
- MSP
Nonstop2h 43m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$255
One-way flights from Minneapolis to South CarolinaSearch for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:20 am
MSP
- CHS
Nonstop2h 41m
Sun Country Air
Deal found 6/7![Sun Country Air logo]()
$78
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:15 am
MSP
- CHS
1 stop4h 35m
Southwest
Deal found 6/7![Southwest logo]()
$106
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am
MSP
- MYR
1 stop6h 50m
Southwest
Deal found 6/7![Southwest logo]()
$106
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:15 am
MSP
- SAV
1 stop4h 15m
Southwest
Deal found 6/8![Southwest logo]()
$106
This Super.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:30 pm
MSP
- CLT
Nonstop2h 38m
Sun Country Air
Deal found 6/8![Sun Country Air logo]()
$108
This Sun Country Air deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/311:05 pm
MSP
- CLT
Nonstop2h 33m
Sun Country Air
Deal found 6/7![Sun Country Air logo]()
$109
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:15 am
MSP
- CLT
1 stop4h 30m
Southwest
Deal found 6/8![Southwest logo]()
$111
This Super.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:18 am
MSP
- CLT
1 stop7h 01m
Frontier
Deal found 6/9![Frontier logo]()
$114
This Super.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:50 am
MSP
- CLT
Nonstop2h 39m
Sun Country Air
Deal found 6/6![Sun Country Air logo]()
$118
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:18 am
MSP
- CLT
1 stop10h 07m
Frontier
Deal found 6/6![Frontier logo]()
$121
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:05 pm
MSP
- CHS
1 stop5h 05m
Southwest
Deal found 6/7![Southwest logo]()
$124
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:45 am
MSP
- CHS
1 stop4h 40m
Southwest
Deal found 6/9![Southwest logo]()
$126
Find flight deals from Minneapolis to South Carolina
Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $212 (Southwest) |
One-way from | $78 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $368 |
Good round-trip deal | $258 or less |
Good one-way deal | $198 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Wed 10/28
7:40 am-5:25 pm
2 stops8h 45m
Charleston
Sat 10/31
6:40 am-2:15 pm
2 stops8h 35m
$265
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Thu 8/27
10:32 am-2:17 pm
Nonstop2h 45m
Charleston
Tue 9/8
3:10 pm-5:15 pm
Nonstop3h 05m
$279
Quickest round-trip
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Wed 9/2
10:32 am-2:17 pm
Nonstop2h 45m
Charleston
Sun 9/6
3:14 pm-5:14 pm
Nonstop3h 00m
$284
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Tue 8/18
6:04 am-12:17 pm
1 stop5h 13m
Charleston
Sun 8/23
3:14 pm-5:14 pm
Nonstop3h 00m
$294
MinneapolisHilton Head Island
MSP - HHH
MSPHHH
Minneapolis St Paul
Wed 8/5
6:00 am-2:21 pm
1 stop7h 21m
Hilton Head Island
Wed 8/12
2:48 pm-9:52 pm
1 stop8h 04m
$301
MinneapolisMyrtle Beach
MSP - MYR
MSPMYR
Minneapolis St Paul
Mon 8/24
7:55 am-5:35 pm
2 stops8h 40m
Myrtle Beach Intl
Thu 8/27
3:20 pm-9:20 pm
2 stops7h 00m
$307
MinneapolisSavannah
MSP - SAV
MSPSAV
Minneapolis St Paul
Fri 10/23
4:25 pm-10:32 pm
1 stop5h 07m
Savannah/Hilton Head
Sat 10/31
5:11 pm-7:15 pm
Nonstop3h 04m
$309
MinneapolisSavannah
MSP - SAV
MSPSAV
Minneapolis St Paul
Tue 8/18
9:00 am-5:30 pm
1 stop7h 30m
Savannah/Hilton Head
Sun 8/23
5:35 am-9:00 am
1 stop4h 25m
$309
MinneapolisHilton Head Island
MSP - HHH
MSPHHH
Minneapolis St Paul
Wed 8/19
8:00 am-2:03 pm
1 stop5h 03m
Hilton Head Island
Mon 8/24
2:48 pm-9:52 pm
1 stop8h 04m
$310
MinneapolisHilton Head Island
MSP - HHH
MSPHHH
Minneapolis St Paul
Sun 10/18
7:00 am-3:19 pm
1 stop7h 19m
Hilton Head Island
Sat 10/24
4:00 pm-9:15 pm
1 stop6h 15m
$310
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
MSP-CLT
MSP-CHS
MSP-MYR
MSP-SAV
MSP-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South Carolina
MSP-USSC
MSP-CLT
MSP-CHS
MSP-MYR
MSP-SAV
What is the cheapest month to book a flight from Minneapolis to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $59). Flying from Minneapolis to South Carolina in January is currently the most expensive (average of $199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to SC?
Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 10, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to South Carolina as you normally would.
How much does it cost to fly round-trip from Minneapolis to South Carolina?
How far ahead should I book a flight from Minneapolis to South Carolina?
The price you pay for your flight from Minneapolis to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 73 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to South Carolina by cabin class
Find flights from Minneapolis to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and South Carolina flights
Browse other Minneapolis and South Carolina flight options. Last updated on June 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Minneapolis to South Carolina flights
Consider these flights traveling from Minneapolis to South Carolina.
Top 5 airlines flying from Minneapolis to South Carolina
Discover the top 5 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$267 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$169 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$195 | Average$392 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$442 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$228 | Average$394 | FlexibilityNo cancel fee | On-time71% |