$109+ Cheap flights from Minneapolis (MSP) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Minneapolis to South CarolinaExplore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:55 am -
1 stop5h 00m
Sat 11/143:55 pm -
1 stop5h 20m
Deal found 9/13![Southwest logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:00 am -
1 stop7h 56m
Fri 11/134:47 pm -
1 stop8h 17m
Deal found 9/11![Frontier logo]()
$241
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:35 am -
1 stop4h 45m
Wed 10/286:40 am -
1 stop4h 40m
Deal found 9/14![Southwest logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:19 am -
1 stop24h 41m
Tue 11/1012:05 pm -
1 stop21h 00m
Deal found 9/9![Frontier logo]()
$242
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
1 stop8h 02m
Wed 10/288:00 am -
Nonstop2h 45m
Deal found 9/10![Multiple Airlines logo]()
$243
This Super.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:10 am -
Nonstop2h 44m
Sun 11/2211:55 am -
Nonstop2h 49m
Deal found 9/13![Sun Country Air logo]()
$246
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:15 am -
Nonstop2h 39m
Sun 11/811:55 am -
Nonstop2h 49m
Deal found 9/10![Sun Country Air logo]()
$247
This FlightHub deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:40 am -
Nonstop2h 33m
Thu 10/812:18 pm -
Nonstop2h 45m
Deal found 9/11![Sun Country Air logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:00 am -
1 stop7h 56m
Sun 11/154:51 pm -
1 stop8h 13m
Deal found 9/12![Frontier logo]()
$250
This Priceline deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:05 pm -
Nonstop2h 33m
Wed 10/214:47 pm -
1 stop8h 19m
Deal found 9/12![Multiple Airlines logo]()
$253
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:55 pm -
1 stop5h 00m
Thu 10/297:35 pm -
1 stop5h 40m
Deal found 9/14![Southwest logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:56 pm -
1 stop15h 20m
Sat 10/1712:05 pm -
1 stop20h 54m
Deal found 9/13![Frontier logo]()
$255
Best flights from Minneapolis to South CarolinaDiscover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Minneapolis to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:50 pm -
Nonstop2h 44m
Wed 11/1111:47 am -
1 stop6h 31m
Deal found 9/13![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop6h 24m
Tue 11/179:07 am -
1 stop6h 20m
Deal found 9/13![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:55 pm -
1 stop5h 40m
Mon 11/28:50 pm -
1 stop4h 50m
Deal found 9/9![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 am -
1 stop7h 06m
Thu 10/2911:36 am -
1 stop6h 43m
Deal found 9/12![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/612:25 pm -
2 stops8h 15m
Mon 11/98:50 pm -
1 stop4h 50m
Deal found 9/9![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:28 pm -
1 stop5h 13m
Wed 11/185:52 pm -
Nonstop3h 04m
Deal found 9/13![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:23 pm -
1 stop4h 39m
Wed 11/1812:21 pm -
2 stops8h 24m
Deal found 9/10![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:16 am -
1 stop7h 28m
Mon 11/235:47 pm -
1 stop6h 04m
Deal found 9/14![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:50 pm -
2 stops8h 05m
Wed 11/117:10 pm -
1 stop4h 50m
Deal found 9/12![Southwest logo]()
$329
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops10h 08m
Tue 11/1710:37 am -
1 stop4h 50m
Deal found 9/10![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:22 am -
Nonstop2h 55m
Sun 12/65:10 am -
1 stop5h 09m
Deal found 9/10![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:45 am -
1 stop6h 12m
Wed 10/1410:23 am -
2 stops8h 36m
Deal found 9/9![United Airlines logo]()
$332
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:15 pm -
1 stop4h 30m
Thu 10/2910:25 am -
2 stops8h 55m
Deal found 9/9![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:01 am -
1 stop7h 17m
Wed 11/2511:06 am -
1 stop6h 17m
Deal found 9/11![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:05 am -
Nonstop2h 35m
Tue 11/107:17 pm -
Nonstop2h 55m
Deal found 9/9![Delta logo]()
$365
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:22 am -
1 stop4h 35m
Tue 10/610:23 am -
2 stops10h 39m
Deal found 9/10![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:35 am -
2 stops7h 50m
Wed 10/75:00 pm -
1 stop6h 50m
Deal found 9/9![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:00 am -
1 stop6h 18m
Wed 12/236:00 am -
1 stop5h 13m
Deal found 9/10![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:00 am -
1 stop6h 10m
Tue 11/1012:25 pm -
2 stops12h 34m
Deal found 9/9![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:03 pm -
2 stops10h 10m
Mon 10/54:25 pm -
1 stop8h 34m
Deal found 9/10![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:50 pm -
1 stop6h 15m
Thu 11/128:20 am -
2 stops9h 20m
Deal found 9/12![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:48 am -
1 stop5h 01m
Sat 11/146:49 am -
1 stop7h 57m
Deal found 9/14![American Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:10 am -
1 stop6h 54m
Wed 12/1611:26 am -
2 stops8h 54m
Deal found 9/12![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:22 am -
1 stop4h 35m
Tue 10/2712:21 pm -
2 stops11h 38m
Deal found 9/12![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:00 am -
2 stops7h 25m
Fri 12/114:00 pm -
2 stops8h 35m
Deal found 9/10![Southwest logo]()
$359
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:15 am -
1 stop4h 57m
Sun 10/115:40 am -
1 stop4h 27m
Deal found 9/12![Delta logo]()
$374
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
2 stops10h 23m
Sun 12/66:15 am -
1 stop5h 12m
Deal found 9/14![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:00 am -
2 stops8h 05m
Sat 12/129:45 am -
2 stops7h 45m
Deal found 9/9![Southwest logo]()
$359
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:59 pm -
1 stop5h 00m
Wed 10/145:00 am -
1 stop5h 13m
Deal found 9/9![American Airlines logo]()
$437
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:25 am -
1 stop7h 24m
Thu 11/55:29 pm -
Nonstop3h 07m
Deal found 9/12![Delta logo]()
$384
Last-minute flights from Minneapolis to South CarolinaDiscover last-minute flight deals from Minneapolis to South Carolina. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to South Carolina. Data last updated September 14, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2512:43 pm -
1 stop6h 27m
Tue 9/2912:05 pm -
1 stop6h 56m
Deal found 9/9![Frontier logo]()
$260
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:15 pm -
1 stop4h 22m
Tue 10/65:40 am -
1 stop4h 25m
Deal found 9/10![Delta logo]()
$259
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:40 am -
Nonstop2h 33m
Thu 10/812:18 pm -
Nonstop2h 45m
Deal found 9/10![Sun Country Air logo]()
$247
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:40 am -
Nonstop2h 33m
Thu 10/159:32 am -
1 stop25h 24m
Deal found 9/9![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:56 pm -
1 stop15h 20m
Sat 10/1712:05 pm -
1 stop20h 54m
Deal found 9/13![Frontier logo]()
$255
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:51 am -
1 stop20h 46m
Thu 10/1511:36 am -
Nonstop2h 45m
Deal found 9/9![Multiple Airlines logo]()
$262
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
1 stop8h 02m
Sat 10/244:47 pm -
1 stop8h 19m
Deal found 9/9![Frontier logo]()
$258
This Priceline deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:05 pm -
Nonstop2h 33m
Wed 10/214:47 pm -
1 stop8h 19m
Deal found 9/12![Multiple Airlines logo]()
$253
This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:00 am -
1 stop8h 02m
Wed 10/288:00 am -
Nonstop2h 45m
Deal found 9/10![Multiple Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:35 am -
1 stop4h 45m
Wed 10/286:40 am -
1 stop4h 40m
Deal found 9/14![Southwest logo]()
$242
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2412:25 pm -
1 stop4h 50m
Thu 10/298:55 pm -
1 stop4h 45m
Deal found 9/13![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:55 pm -
1 stop5h 00m
Thu 10/297:35 pm -
1 stop5h 40m
Deal found 9/14![Southwest logo]()
$253
One-way flights from Minneapolis to South CarolinaSearch for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
Search for one-way flight options from Minneapolis to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 14, 2026.
This Super.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:00 am -
Nonstop2h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Sun Country Air logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:01 pm -
2 stops16h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:33 am -
2 stops22h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$118
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/411:40 am -
Nonstop2h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Sun Country Air logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:01 pm -
2 stops21h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/103:01 pm -
2 stops40h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:45 pm -
2 stops23h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$123
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:50 pm -
1 stop6h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/93:01 pm -
2 stops40h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:52 pm -
2 stops20h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/209:33 am -
2 stops33h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/129:55 am -
2 stops27h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$128
Find flight deals from Minneapolis to South Carolina
Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $218 (Southwest) |
One-way from | $109 (Super.com) |
Popular in | October |
Cheapest in | May |
Average price | $386 |
Good round-trip deal | $329 or less |
Good one-way deal | $368 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisCharlotte
MSP Minneapolis St Paul - CLT Charlotte Douglas
MSPCLT
Minneapolis St Paul
Fri 11/6
8:15 am-11:54 am
Nonstop2h 39m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Mon 11/9
2:50 pm-10:05 pm
1 stop6h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$123
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 10/20
9:33 am-7:44 pm
2 stops33h 11m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$127
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 11/3
3:01 pm-7:44 pm
2 stops27h 43m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$128
MinneapolisGreenville
MSP Minneapolis St Paul - GSP Greenville
MSPGSP
Minneapolis St Paul
Tue 10/6
5:25 am-1:00 pm
1 stop6h 35m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$130
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Fri 11/13
2:50 pm-10:05 pm
1 stop6h 15m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$137
Quickest round-trip
MinneapolisCharlotte
MSP Minneapolis St Paul - CLT Charlotte Douglas
MSPCLT
Minneapolis St Paul
Tue 10/13
8:25 am-11:58 am
Nonstop2h 33m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$149
MinneapolisSavannah
MSP Minneapolis St Paul - SAV Savannah/Hilton Head
MSPSAV
Minneapolis St Paul
Fri 11/13
5:15 pm-11:55 pm
1 stop5h 40m
Savannah/Hilton Head
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$153
MinneapolisCharlotte
MSP Minneapolis St Paul - CLT Charlotte Douglas
MSPCLT
Minneapolis St Paul
Sun 10/11
2:20 pm-5:53 pm
Nonstop2h 33m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$159
MinneapolisMyrtle Beach
MSP Minneapolis St Paul - MYR Myrtle Beach Intl
MSPMYR
Minneapolis St Paul
Sat 10/3
3:01 pm-9:08 pm
1 stop5h 07m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$165
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
MSP-MYR
MSP-CLT
MSP-CHS
MSP-SAV
MSP-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South Carolina
MSP-USSC
MSP-MYR
MSP-CLT
MSP-CHS
MSP-SAV
What is the cheapest month to book a flight from Minneapolis to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $324). Flying from Minneapolis to South Carolina in March is currently the most expensive (average of $433). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to SC?
Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Minneapolis to South Carolina as you normally would.
Weekly flight availability from Minneapolis to South Carolina
Explore weekly flight availability from Minneapolis to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 14, 2026.
The most flights from MSP to USSC are scheduled on a Monday (3 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Minneapolis to South Carolina?
Airfare is below average for this route at the moment.
Minneapolis to South Carolina flights typically cost between $319 and $498 in October.The cheapest round-trip price found within the last 5 days was $242 on Southwest (Oct 24-Oct 28).
How far ahead should I book a flight from Minneapolis to South Carolina?
The price you pay for your flight from Minneapolis to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 74 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 14, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
4.0
OkaySteven,Sep 2026
OGG - HNL
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Minneapolis to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and South Carolina flights
Browse other Minneapolis and South Carolina flight options. Last updated on September 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Minneapolis to South Carolina flights
Consider these flights traveling from Minneapolis to South Carolina.
Top 5 airlines flying from Minneapolis to South Carolina
Discover the top 5 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$68 | Average$260 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$206 | Average$412 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$478 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$237 | Average$399 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$261 | Average$431 | FlexibilityNo cancel fee | On-time71% |