$64+ Cheap flights from Minneapolis (MSP) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/8. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Jan 11 — Jan 181
1 adult, Economy
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Cheapest flights from Minneapolis to South CarolinaExplore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.
This Expedia deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:09 pmMSP - CLT
1 stop10h 48mFrontier
Wed 12/245:14 pmCLT - MSP
1 stop7h 48mFrontier
Deal found 12/11![Frontier logo]()
$264
This Southwest deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:30 amMSP - CLT
1 stop4h 50mSouthwest
Thu 1/16:20 pmCLT - MSP
1 stop4h 55mSouthwest
Deal found 12/9![Southwest logo]()
$275
This Super.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:34 pmMSP - CLT
1 stop19h 45mFrontier
Fri 12/269:47 amCLT - MSP
1 stop5h 15mFrontier
Deal found 12/9![Frontier logo]()
$292
This Frontier deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:42 pmMSP - CLT
1 stop13h 40mFrontier
Fri 12/269:47 amCLT - MSP
1 stop5h 15mFrontier
Deal found 12/11![Frontier logo]()
$293
This Frontier deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:00 amMSP - CLT
1 stop8h 49mFrontier
Wed 12/245:14 pmCLT - MSP
1 stop7h 48mFrontier
Deal found 12/9![Frontier logo]()
$298
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:00 pmMSP - CLT
Nonstop2h 37mDelta
Tue 12/306:20 amCLT - MSP
Nonstop2h 55mDelta
Deal found 12/10![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:00 pmMSP - CLT
Nonstop2h 37mDelta
Wed 1/75:00 pmCLT - MSP
1 stop4h 58mDelta
Deal found 12/9![Delta logo]()
$309
This Mytrip deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:45 amMSP - CLT
1 stop27h 37mFrontier
Wed 12/315:14 pmCLT - MSP
1 stop7h 48mFrontier
Deal found 12/9![Frontier logo]()
$317
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amMSP - CLT
1 stop5h 25mDelta
Wed 1/76:00 amCLT - MSP
1 stop5h 25mDelta
Deal found 12/9![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:45 amMSP - CLT
1 stop27h 37mFrontier
Sun 1/49:24 amCLT - MSP
2 stops39h 38mFrontier
Deal found 12/11![Frontier logo]()
$330
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:00 pmMSP - CLT
Nonstop2h 37mDelta
Thu 1/16:20 amCLT - MSP
Nonstop2h 55mDelta
Deal found 12/10![Delta logo]()
$331
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:00 amMSP - CLT
1 stop8h 49mFrontier
Sun 12/145:44 pmCLT - MSP
1 stop7h 18mFrontier
Deal found 12/9![Frontier logo]()
$332
Find flight deals from Minneapolis to South Carolina
Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated December 12, 2025.
Most accurate provider | Mytrip 3 stars |
|---|---|
Most trusted provider | Mytrip 3 stars |
Round-trip from | $138 (Mytrip) |
One-way from | $64 (Frontier) |
Popular in | March |
Cheapest in | September |
Average price | $368 |
Good round-trip deal | $259 or less |
Good one-way deal | $308 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.
Fly from
Minneapolis
Fly to
South Carolina
Route
Depart
Return
Price
MinneapolisSavannah
MSP - SAV
MSPSAV
Minneapolis St Paul
Mon 1/26
10:20 am-2:07 pm
Nonstop2h 47m
Savannah/Hilton Head
Sat 1/31
3:05 pm-5:15 pm
Nonstop3h 10m
$245
MinneapolisMyrtle Beach
MSP - MYR
MSPMYR
Minneapolis St Paul
Sat 1/24
4:47 pm-11:38 pm
1 stop5h 51m
Myrtle Beach Intl
Sat 1/31
1:53 pm-9:47 pm
2 stops8h 54m
$256
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Fri 2/6
11:20 am-8:02 pm
1 stop7h 42m
Charleston
Sun 2/8
6:00 am-12:19 pm
1 stop7h 19m
$265
MinneapolisCharlotte
MSP - CLT
MSPCLT
Minneapolis St Paul
Sun 1/11
6:45 am-3:00 pm
2 stops31h 15m
Charlotte Douglas
Fri 1/16
8:48 am-8:39 pm
1 stop12h 51m
$265
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Sat 1/10
6:10 pm-11:55 pm
1 stop4h 45m
Charleston
Tue 1/13
11:28 am-5:33 pm
1 stop7h 05m
$265
MinneapolisCharlotte
MSP - CLT
MSPCLT
Minneapolis St Paul
Tue 2/3
1:00 pm-4:28 pm
Nonstop2h 28m
Charlotte Douglas
Tue 2/10
6:00 am-10:25 am
1 stop5h 25m
$265
MinneapolisSavannah
MSP - SAV
MSPSAV
Minneapolis St Paul
Wed 1/14
6:55 am-4:46 pm
1 stop8h 51m
Savannah/Hilton Head
Wed 1/21
11:46 am-5:33 pm
1 stop6h 47m
$265
MinneapolisSavannah
MSP - SAV
MSPSAV
Minneapolis St Paul
Tue 2/17
10:20 am-2:07 pm
Nonstop2h 47m
Savannah/Hilton Head
Thu 2/26
5:30 am-9:16 am
1 stop4h 46m
$269
MinneapolisCharleston
MSP - CHS
MSPCHS
Minneapolis St Paul
Thu 2/5
6:00 am-2:48 pm
2 stops7h 48m
Charleston
Sun 2/8
6:00 am-12:19 pm
1 stop7h 19m
$270
MinneapolisMyrtle Beach
MSP - MYR
MSPMYR
Minneapolis St Paul
Thu 1/22
4:00 pm-11:15 pm
1 stop6h 15m
Myrtle Beach Intl
Sat 1/31
10:18 am-5:09 pm
2 stops7h 51m
$270
Showing 1-10 of 60 results
Best time to book a flight from Minneapolis to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South Carolina
What is the cheapest month to book a flight from Minneapolis to South Carolina?
Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $69). Flying from Minneapolis to South Carolina in July is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MSP to SC?
Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.
One of the essential ways to save on airfare from Minneapolis to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 55% on airfare.
What is the cheapest day to fly from Minneapolis to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Minneapolis to South Carolina. Price data was last updated on December 16, 2024.
Travelers seeking maximum savings on their Minneapolis to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 12, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from Minneapolis to South Carolina
Discover the top 6 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$69 | Average$224 | FlexibilityNo cancel fee | On-time83% | |
| Cheapest$145 | Average$253 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$208 | Average$386 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$420 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$382 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$242 | Average$403 | FlexibilityNo cancel fee | On-time63% |