South Carolina

$59+ Cheap flights from Minneapolis (MSP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
feb. 26 — mar. 51
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Cheap flight deals from Minneapolis to South Carolina

Cheapest flights from Minneapolis to South Carolina
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 27, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/207:48 am
MSP
-
MYR
Nonstop2h 39m
Sun Country Air
vie. 4/2412:04 pm
MYR
-
MSP
Nonstop3h 02m
Sun Country Air
Deal found 1/25$188
This Cheapflightsfares deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/18:05 am
MSP
-
MYR
Nonstop2h 33m
Sun Country Air
vie. 5/81:20 pm
MYR
-
MSP
Nonstop2h 58m
Sun Country Air
Deal found 1/24$197
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/18:05 am
MSP
-
MYR
Nonstop2h 33m
Sun Country Air
lun. 5/41:15 pm
MYR
-
MSP
Nonstop2h 58m
Sun Country Air
Deal found 1/27$217
This Sun Country Air deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/138:24 am
MSP
-
MYR
Nonstop2h 39m
Sun Country Air
vie. 4/1712:34 pm
MYR
-
MSP
Nonstop3h 02m
Sun Country Air
Deal found 1/24$238
This Sun Country Air deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/207:48 am
MSP
-
MYR
Nonstop2h 39m
Sun Country Air
lun. 4/2712:28 pm
MYR
-
MSP
Nonstop3h 02m
Sun Country Air
Deal found 1/24$248
This Sun Country Air deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/237:48 am
MSP
-
SAV
Nonstop2h 45m
Sun Country Air
jue. 4/3012:00 pm
SAV
-
MSP
Nonstop3h 01m
Sun Country Air
Deal found 1/24$248
This Cheapflightsfares deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/77:20 am
MSP
-
SAV
Nonstop2h 41m
Sun Country Air
dom. 5/1012:00 pm
SAV
-
MSP
Nonstop3h 01m
Sun Country Air
Deal found 1/25$257
This Sun Country Air deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/178:00 am
MSP
-
MYR
Nonstop2h 39m
Sun Country Air
vie. 4/2412:04 pm
MYR
-
MSP
Nonstop3h 02m
Sun Country Air
Deal found 1/24$258
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/2410:00 am
MSP
-
MYR
Nonstop2h 39m
Delta
jue. 7/302:40 pm
MYR
-
MSP
Nonstop3h 01m
Delta
Deal found 1/25$259
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/217:15 am
MSP
-
CLT
2 stops23h 43m
Frontier
mié. 2/252:46 pm
CLT
-
MSP
1 stop29h 46m
Frontier
Deal found 1/26$262
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/217:15 am
MSP
-
CLT
2 stops23h 43m
Multiple Airlines
mié. 2/255:49 pm
CLT
-
MSP
1 stop26h 43m
Multiple Airlines
Deal found 1/25$263
This Priceline deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/126:45 am
MSP
-
CLT
1 stop8h 33m
Multiple Airlines
dom. 2/1511:45 am
CLT
-
MSP
Nonstop2h 46m
Multiple Airlines
Deal found 1/24$264

Find flight deals from Minneapolis to South Carolina

Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated enero 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$188
(Cheapflightsfares)

One-way from

$59
(Sun Country Air)

Popular in

March

Cheapest in

September

Average price

$334

Good round-trip deal

$213 or less

Good one-way deal

$168 or less
Provider with most accurate pricing for Minneapolis St Paul-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Minneapolis St Paul-Myrtle Beach Intl flights.
From Minneapolis St Paul to South Carolina
One-way flight from Minneapolis St Paul to South Carolina
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Average for round-trip flights in January 2026
Price to beat on a round-trip flight from Minneapolis St Paul to South Carolina.
Price to beat on a one-way flight from Minneapolis St Paul to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.

Fly from

Minneapolis

Fly to

South Carolina

Route

Depart

Return

Price

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

dom. 4/19

10:00 am-6:06 pm

1 stop7h 06m

Myrtle Beach Intl

jue. 4/30

3:57 pm-5:56 pm

Nonstop2h 59m

$269

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

mar. 4/21

11:26 am-3:06 pm

Nonstop2h 40m

Myrtle Beach Intl

sáb. 4/25

12:00 pm-6:52 pm

1 stop7h 52m

$269

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

mar. 4/21

11:26 am-3:06 pm

Nonstop2h 40m

Myrtle Beach Intl

mar. 4/28

12:00 pm-7:05 pm

1 stop8h 05m

$269

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

dom. 4/19

11:26 am-3:06 pm

Nonstop2h 40m

Myrtle Beach Intl

sáb. 4/25

12:00 pm-6:52 pm

1 stop7h 52m

$269

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

sáb. 4/18

4:32 pm-12:14 am

1 stop6h 42m

Myrtle Beach Intl

mié. 4/29

3:57 pm-5:56 pm

Nonstop2h 59m

$269

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

sáb. 3/28

7:49 pm-11:19 pm

Nonstop2h 30m

Charlotte Douglas

mié. 4/1

6:18 am-8:10 am

Nonstop2h 52m

$275

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

dom. 4/5

8:13 am-2:17 pm

1 stop5h 04m

Myrtle Beach Intl

vie. 4/10

3:15 pm-7:23 pm

1 stop5h 08m

$279

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

lun. 3/2

7:00 am-4:49 pm

1 stop8h 49m

Myrtle Beach Intl

jue. 3/5

6:05 pm-11:59 pm

1 stop6h 54m

$279

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

jue. 2/26

7:00 am-2:21 pm

1 stop6h 21m

Columbia Metropolitan

mar. 3/3

5:35 am-9:16 am

1 stop4h 41m

$279

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

mar. 3/10

1:55 pm-9:24 pm

1 stop6h 29m

Columbia Metropolitan

mar. 3/17

5:34 am-9:12 am

1 stop4h 38m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 60 results
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Best time to book a flight from Minneapolis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South Carolina

What is the cheapest month to book a flight from Minneapolis to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $69). Flying from Minneapolis to South Carolina in July is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SC?

Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 27, 2026.

One of the essential ways to save on airfare from Minneapolis to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 48% on airfare.

What is the cheapest day to fly from Minneapolis to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Minneapolis to South Carolina. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Minneapolis to South Carolina flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated enero 27, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Minneapolis to South Carolina?

    Located just 7.3 mi from the city center, Minneapolis St Paul (MSP) is the airport most travelers will use when flying to South Carolina from Minneapolis.

  • How popular is this Minneapolis to South Carolina flight route?

  • How long is the flight from Minneapolis to South Carolina?

    A quick flight from Minneapolis to South Carolina can take about 5h 55m. Delta provides one of the quickest options available for as low as $293. There are 1091 mi between Minneapolis and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Minneapolis to South Carolina one-way?

    For one-way options, check prices for Sun Country Air. According to our data, you can fly for as low as $60. Users have also found prices from $99 and $128 on American Airlines and Southwest, respectively.

  • What are the most popular routes from Minneapolis to South Carolina?

  • What are the most reliable airlines from Minneapolis to South Carolina?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Minneapolis to South Carolina on time: Delta (53%), KLM (50%), Endeavor Airlines (48%).

  • What are the cheapest flights from Minneapolis to South Carolina?

    On average you can expect to pay $398 for a flight from Minneapolis to South Carolina. The cheapest flight overall is $60 while the most popular route, (Minneapolis St Paul - Charleston) is currently priced at $148.

  • Can I find deals for flights from Minneapolis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Minneapolis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South Carolina.

  • Can I find deals for business class flights from Minneapolis to South Carolina?

    Yes. Cheapflights offers flight deals from Minneapolis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $69). Flying from Minneapolis to South Carolina in July is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Minneapolis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Minneapolis to South Carolina

Discover the top 6 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Sun Country AirCheapest$68Average$211FlexibilityNo cancel feeOn-time83%
Spirit AirlinesCheapest$145Average$238FlexibilityNo cancel feeOn-time65%
DeltaCheapest$148Average$374FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$218Average$406FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$232Average$384FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$238Average$399FlexibilityNo cancel feeOn-time63%

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