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$59+ Cheap flights from Minneapolis (MSP) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — CHS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Minneapolis to South Carolina

Keep the following information in mind while searching for Minneapolis to South Carolina flight deals. Data was last updated October 29, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$214
(Kiwi.com)

One-way from

$59
(Sun Country Air)

Popular in

March

Cheapest in

September

Average price

$378

Good round-trip deal

$299 or less

Good one-way deal

$358 or less
Provider with most accurate pricing for Minneapolis St Paul-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Minneapolis St Paul-Myrtle Beach Intl flights.
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From Minneapolis St Paul to South Carolina
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One-way flight from Minneapolis St Paul to South Carolina
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Highest demand for flights based on searches. 3% potential increase in price ($12 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Minneapolis St Paul to South Carolina.
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Price to beat on a one-way flight from Minneapolis St Paul to South Carolina.
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Find flight deals from Minneapolis to South Carolina

Cheapest flights from Minneapolis to South Carolina
Explore the most affordable flight options available from Minneapolis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:00 amMSP - CHS
2 stops34h 06mMultiple Airlines
Thu 11/208:31 amCHS - MSP
1 stop6h 23mMultiple Airlines
Deal found 10/27$214
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:41 amMSP - CLT
2 stops28h 48mMultiple Airlines
Wed 11/266:02 pmCLT - MSP
Nonstop2h 49mMultiple Airlines
Deal found 10/27$216
This Booking.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:12 amMSP - CLT
Nonstop2h 35mMultiple Airlines
Mon 11/36:21 pmCLT - MSP
1 stop29h 26mMultiple Airlines
Deal found 10/27$221
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:23 amMSP - CLT
2 stops21h 53mFrontier
Thu 12/45:49 pmCLT - MSP
1 stop25h 23mFrontier
Deal found 10/28$222
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:18 amMSP - CLT
1 stop23h 14mMultiple Airlines
Tue 12/3010:52 amCLT - MSP
1 stop10h 31mMultiple Airlines
Deal found 10/27$223
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/287:42 amMSP - CLT
1 stop9h 49mMultiple Airlines
Fri 12/55:44 pmCLT - MSP
1 stop30h 30mMultiple Airlines
Deal found 10/28$225
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/107:12 amMSP - CLT
3 stops34h 42mMultiple Airlines
Thu 11/136:38 pmCLT - MSP
Nonstop2h 49mMultiple Airlines
Deal found 10/27$226
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:41 amMSP - CLT
2 stops28h 48mMultiple Airlines
Mon 11/246:56 pmCLT - MSP
Nonstop2h 49mMultiple Airlines
Deal found 10/27$227
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMSP - CLT
1 stop10h 17mFrontier
Mon 11/106:07 pmCLT - MSP
1 stop7h 07mFrontier
Deal found 10/28$228
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:12 amMSP - CLT
Nonstop2h 44mMultiple Airlines
Thu 11/139:34 amCLT - MSP
3 stops27h 26mMultiple Airlines
Deal found 10/27$233
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:12 amMSP - CLT
Nonstop2h 35mMultiple Airlines
Wed 11/58:05 pmCLT - MSP
2 stops16h 26mMultiple Airlines
Deal found 10/27$234
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amMSP - CLT
1 stop27h 37mFrontier
Mon 1/512:17 pmCLT - MSP
1 stop9h 34mFrontier
Deal found 10/28$236

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Minneapolis to South Carolina that are best for you.

Fly from

Minneapolis

Fly to

South Carolina

Route

Depart

Return

Price

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

Tue 12/23

4:49 pm-12:26 am

1 stop6h 37m

Columbia Metropolitan

Tue 1/6

2:49 pm-11:41 pm

2 stops9h 52m

$264

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Wed 12/10

7:05 am-10:53 am

Nonstop2h 48m

Charlotte Douglas

Wed 12/17

8:19 am-12:15 pm

1 stop4h 56m

$265

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Thu 11/27

7:25 am-5:00 pm

1 stop8h 35m

Myrtle Beach Intl

Tue 12/2

7:30 am-11:31 am

1 stop5h 01m

$265

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Fri 12/12

1:40 pm-7:40 pm

1 stop5h 00m

Myrtle Beach Intl

Wed 12/17

2:55 pm-7:05 pm

1 stop5h 10m

$265

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Fri 1/9

7:00 am-3:13 pm

1 stop7h 13m

Myrtle Beach Intl

Tue 1/13

10:33 am-3:26 pm

1 stop5h 53m

$265

MinneapolisMyrtle Beach

MSP - MYR

MSPMYR

Minneapolis St Paul

Fri 1/9

7:00 am-2:55 pm

1 stop6h 55m

Myrtle Beach Intl

Tue 1/13

10:18 am-5:00 pm

2 stops7h 42m

$270

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

Sun 11/16

6:00 am-1:47 pm

1 stop6h 47m

Columbia Metropolitan

Sat 11/22

5:24 pm-9:35 pm

1 stop5h 11m

$274

MinneapolisColumbia

MSP - CAE

MSPCAE

Minneapolis St Paul

Mon 11/17

12:51 pm-6:34 pm

1 stop4h 43m

Columbia Metropolitan

Fri 11/28

5:06 am-9:19 am

1 stop5h 13m

$274

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Thu 12/18

6:30 am-12:25 pm

1 stop4h 55m

Charlotte Douglas

Mon 1/5

5:50 am-9:25 am

1 stop4h 35m

$275

MinneapolisCharlotte

MSP - CLT

MSPCLT

Minneapolis St Paul

Wed 12/10

6:30 am-12:20 pm

1 stop4h 50m

Charlotte Douglas

Wed 12/10

6:20 pm-10:15 pm

1 stop4h 55m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 60 results
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Best time to book a flight from Minneapolis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South Carolina

What is the cheapest month to book a flight from Minneapolis to South Carolina?

Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $81). Flying from Minneapolis to South Carolina in July is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SC?

Find hourly flight availability from Minneapolis to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

One of the essential ways to save on airfare from Minneapolis to South Carolina is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 53% on airfare.

What is the cheapest day to fly from Minneapolis to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Minneapolis to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Minneapolis to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Minneapolis to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,001 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Sun Country Air
6.9
Okay
335 reviews
Southwest
8.0
Very good
4,240 reviews

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to South Carolina?

    Located just 7.3 mi from the city center, Minneapolis St Paul (MSP) is the airport most travelers will use when flying to South Carolina from Minneapolis.

  • How popular is this Minneapolis to South Carolina flight route?

    This flight path from Minneapolis St Paul to South Carolina was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Minneapolis to South Carolina?

    A quick flight from Minneapolis to South Carolina can take about 2h 48m. United Airlines provides one of the quickest options available for as low as $265. There are 928 mi between Minneapolis and South Carolina. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Minneapolis to South Carolina one-way?

    For one-way options, check prices for Sun Country Air. According to our data, you can fly for as low as $59. Users have also found prices from $85 and $118 on Frontier and Spirit Airlines, respectively.

  • What are the most popular routes from Minneapolis to South Carolina?

    While some choose either Minneapolis St Paul - Charleston or Minneapolis St Paul - Savannah/Hilton Head, Minneapolis St Paul - Charlotte Douglas is the most popular route from Minneapolis to South Carolina.

  • What are the cheapest flights from Minneapolis to South Carolina?

    On average you can expect to pay $418 for a flight from Minneapolis to South Carolina. The cheapest flight overall is $188 while the most popular route, (Minneapolis St Paul - Charlotte Douglas) is currently priced at $128.

  • Can I find deals for flights from Minneapolis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Minneapolis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South Carolina.

  • Can I find deals for business class flights from Minneapolis to South Carolina?

    Yes. Cheapflights offers flight deals from Minneapolis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to South Carolina?

    Currently, May is the cheapest month in which you can book a flight from Minneapolis to South Carolina (average of $81). Flying from Minneapolis to South Carolina in July is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Minneapolis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Minneapolis to South Carolina

Discover the top 6 airlines that operate flights from Minneapolis to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Sun Country AirCheapest$69Average$220FlexibilityNo cancel feeOn-time83%
Spirit AirlinesCheapest$145Average$258FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$206Average$371FlexibilityNo cancel feeOn-time71%
DeltaCheapest$209Average$386FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$218Average$382FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$242Average$399FlexibilityNo cancel feeOn-time63%

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