HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$129+ Cheap flights from Lexington (LEX) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — CHS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Lexington to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Lexington to South Carolina

Cheapest flights from Lexington to South Carolina
Explore the most affordable flight options available from Lexington to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:11 pmLEX - SAV
1 stop8h 19mAmerican Airlines
Wed 12/247:00 amSAV - LEX
1 stop6h 23mAmerican Airlines
Deal found 12/16$309
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amLEX - SAV
1 stop7h 49mAmerican Airlines
Mon 1/58:15 pmSAV - LEX
1 stop3h 41mAmerican Airlines
Deal found 12/16$321
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:03 pmLEX - SAV
1 stop6h 10mAmerican Airlines
Sun 12/285:05 amSAV - LEX
1 stop5h 25mAmerican Airlines
Deal found 12/15$341
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:03 pmLEX - SAV
1 stop6h 10mAmerican Airlines
Sat 12/276:13 pmSAV - LEX
1 stop5h 30mAmerican Airlines
Deal found 12/16$367
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:08 amLEX - GSP
1 stop6h 06mAmerican Airlines
Fri 1/212:44 pmGSP - LEX
1 stop4h 49mAmerican Airlines
Deal found 12/15$392
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:05 amLEX - AGS
1 stop6h 45mAmerican Airlines
Sat 1/38:32 pmAGS - LEX
1 stop3h 24mAmerican Airlines
Deal found 12/15$407
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:16 pmLEX - MYR
1 stop4h 58mDelta
Sat 12/276:00 amMYR - LEX
1 stop3h 57mDelta
Deal found 12/17$433
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:05 amLEX - CAE
1 stop4h 07mDelta
Sat 1/36:00 amCAE - LEX
1 stop3h 57mDelta
Deal found 12/16$445
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:04 amLEX - SAV
2 stops7h 58mAmerican Airlines
Sat 12/273:30 pmSAV - LEX
1 stop6h 31mAmerican Airlines
Deal found 12/16$452
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:05 amLEX - GSP
1 stop4h 14mAmerican Airlines
Sat 1/36:20 pmGSP - LEX
1 stop3h 41mAmerican Airlines
Deal found 12/15$465
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:09 amLEX - AGS
1 stop4h 40mAmerican Airlines
Thu 12/251:06 pmAGS - LEX
1 stop4h 27mAmerican Airlines
Deal found 12/17$472
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:04 amLEX - CLT
1 stop11h 06mAmerican Airlines
Wed 12/318:15 amCLT - LEX
1 stop38h 57mAmerican Airlines
Deal found 12/17$480

Find flight deals from Lexington to South Carolina

Keep the following information in mind while searching for Lexington to South Carolina flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$221
(American Airlines)

One-way from

$129
(Kiwi.com)

Popular in

March

Cheapest in

July

Average price

$413
Provider with most accurate pricing for Lexington Blue Grass-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Myrtle Beach Intl flights.
Search Deals
From Lexington Blue Grass to South Carolina
Search Deals
One-way flight from Lexington Blue Grass to South Carolina
Search Deals
Highest demand for flights based on searches. 31% potential increase in price ($148 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Lexington to South Carolina that are best for you.

Fly from

Lexington

Fly to

South Carolina

Route

Depart

Return

Price

LexingtonMyrtle Beach

LEX - MYR

LEXMYR

Lexington Blue Grass

Fri 1/16

7:17 pm-11:15 pm

1 stop3h 58m

Myrtle Beach Intl

Tue 1/20

5:29 pm-11:15 pm

1 stop5h 46m

$221

LexingtonMyrtle Beach

LEX - MYR

LEXMYR

Lexington Blue Grass

Wed 5/27

10:57 am-5:16 pm

1 stop6h 19m

Myrtle Beach Intl

Sat 5/30

6:43 pm-9:43 pm

1 stop3h 00m

$249

LexingtonMyrtle Beach

LEX - MYR

LEXMYR

Lexington Blue Grass

Sat 1/24

7:23 pm-11:38 pm

1 stop4h 15m

Myrtle Beach Intl

Wed 2/18

10:20 am-2:39 pm

1 stop4h 19m

$249

LexingtonMyrtle Beach

LEX - MYR

LEXMYR

Lexington Blue Grass

Thu 1/29

7:17 pm-11:15 pm

1 stop3h 58m

Myrtle Beach Intl

Sun 2/8

10:48 am-5:53 pm

1 stop7h 05m

$249

LexingtonSavannah

LEX - SAV

LEXSAV

Lexington Blue Grass

Sat 4/18

8:20 pm-11:45 pm

1 stop3h 25m

Savannah/Hilton Head

Sat 4/25

7:22 am-1:19 pm

1 stop5h 57m

$249

LexingtonSavannah

LEX - SAV

LEXSAV

Lexington Blue Grass

Fri 1/9

6:00 am-9:55 am

1 stop3h 55m

Savannah/Hilton Head

Mon 1/12

7:00 am-10:56 am

1 stop3h 56m

$249

LexingtonCharleston

LEX - CHS

LEXCHS

Lexington Blue Grass

Tue 1/13

10:30 am-7:04 pm

2 stops8h 34m

Charleston

Tue 1/20

4:41 pm-10:40 pm

1 stop5h 59m

$254

LexingtonSavannah

LEX - SAV

LEXSAV

Lexington Blue Grass

Tue 2/17

3:10 pm-6:45 pm

1 stop3h 35m

Savannah/Hilton Head

Sat 2/21

4:12 pm-11:33 pm

2 stops7h 21m

$254

LexingtonCharlotte

LEX - CLT

LEXCLT

Lexington Blue Grass

Thu 1/8

11:51 am-2:20 pm

2 stops26h 29m

Charlotte Douglas

Mon 1/12

11:12 am-8:40 pm

1 stop9h 28m

$256

LexingtonMyrtle Beach

LEX - MYR

LEXMYR

Lexington Blue Grass

Thu 1/1

6:20 am-10:42 am

1 stop4h 22m

Myrtle Beach Intl

Mon 1/5

4:00 pm-8:01 pm

1 stop4h 01m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 56 results
1
2
3
...
6

Best time to book a flight from Lexington to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to South Carolina

What is the cheapest month to book a flight from Lexington to South Carolina?

Currently, October is the cheapest month in which you can book a flight from Lexington to South Carolina (average of $41). Flying from Lexington to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to SC?

Find hourly flight availability from Lexington to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Lexington to South Carolina in the afternoon. Doing so could potentially save you 25% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Lexington to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Lexington to South Carolina. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Lexington to South Carolina flight should consider departing on Sunday mornings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated December 18, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Lexington to South Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Allegiant Air
7.2
Good
700 reviews
Delta
7.9
Good
8,005 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lexington to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lexington to South Carolina?

    Most people fly from Lexington Blue Grass (LEX) if they book a flight from Lexington to South Carolina. Lexington Blue Grass is conveniently located just 5.6 mi from Lexington’s city center.

  • How long is the flight from Lexington to South Carolina?

    There are many flights that can get you from Lexington to South Carolina in 3h 58m. Fly via American Airlines, United Airlines, or Delta to get the fastest option. The distance between Lexington and South Carolina is about 437 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Lexington to South Carolina?

    Most travelers choose Lexington Blue Grass - Charlotte Douglas, Lexington Blue Grass - Savannah/Hilton Head or Lexington Blue Grass - Myrtle Beach Intl when deciding on the best route from Lexington to South Carolina.

  • Can I find deals for flights from Lexington to South Carolina that include hotel bookings?

    Yes. In addition to deals on Lexington to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to South Carolina.

  • Can I find deals for business class flights from Lexington to South Carolina?

    Yes. Cheapflights offers flight deals from Lexington to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Lexington to South Carolina (average of $41). Flying from Lexington to South Carolina in November is currently the most expensive (average of $82). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Lexington to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Orlando flights
Cincinnati to Fort Lauderdale flights
Cincinnati to John F Kennedy Intl flights
Cincinnati to Las Vegas flights
Nashville to John F Kennedy Intl flights
Cincinnati to LaGuardia flights
Cincinnati to Los Angeles flights
Cincinnati to Newark flights
Cincinnati to Fort Myers flights
Nashville to LaGuardia flights
Cincinnati to Tampa flights
Nashville to Newark flights
Cincinnati to Sky Harbor Intl flights
Cincinnati to Hobby flights
Cincinnati to Denver flights
Cincinnati to Miami flights
Nashville to Dallas/Fort Worth flights
Nashville to Miami flights
Nashville to Los Angeles flights
Cincinnati to Dallas/Fort Worth flights
Nashville to Fort Lauderdale flights
Nashville to Orlando flights
Nashville to Las Vegas flights
Nashville to Denver flights
Cincinnati to George Bush Intcntl flights
Louisville to Las Vegas flights
Nashville to Seattle flights
Louisville to Miami flights
Nashville to O'Hare Intl flights
Cincinnati to Boston flights
Nashville to Sky Harbor Intl flights
Cincinnati to Seattle flights
Nashville to Dulles Intl flights
Louisville to LaGuardia flights
Louisville to Fort Lauderdale flights
Cincinnati to Atlanta flights
Nashville to Hobby flights
Nashville to Reagan-National flights
Nashville to Tampa flights
Nashville to Boston flights
Cincinnati to Ontario flights
Cincinnati to Orlando Sanford Intl flights
Louisville to Orlando flights
Cincinnati to O'Hare Intl flights
Cincinnati to Salt Lake City flights
Nashville to Sarasota flights
Nashville to Baltimore flights
Nashville to Salt Lake City flights
Knoxville to Denver flights
Louisville to Newark flights

Top 4 airlines flying from Lexington to South Carolina

Discover the top 4 airlines that operate flights from Lexington to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$84Average$99FlexibilityNo cancel feeOn-time88%
DeltaCheapest$198Average$371FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$431FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$308FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.