HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$228+ Cheap flights from Hyannis (HYA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
HYA — CHS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Hyannis to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Hyannis to South Carolina

Cheapest flights from Hyannis to South Carolina
Explore the most affordable flight options available from Hyannis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This JetBlue deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:05 amHYA - CHS
1 stop4h 31mJetBlue
Tue 12/3012:21 pmCHS - HYA
1 stop4h 59mJetBlue
Deal found 12/16$765
This JetBlue deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:05 amHYA - CHS
1 stop4h 31mJetBlue
Mon 12/2912:21 pmCHS - HYA
1 stop4h 59mJetBlue
Deal found 12/16$843
This JetBlue deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:05 amHYA - CHS
1 stop4h 31mJetBlue
Sat 1/312:42 pmCHS - HYA
1 stop4h 38mJetBlue
Deal found 12/16$919
This JetBlue deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:05 amHYA - CHS
1 stop4h 31mJetBlue
Mon 12/2912:21 pmCHS - HYA
1 stop4h 59mJetBlue
Deal found 12/16$1,033
This JetBlue deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:05 amHYA - CHS
1 stop4h 52mJetBlue
Sun 12/2812:21 pmCHS - HYA
1 stop4h 59mJetBlue
Deal found 12/17$1,260

Find flight deals from Hyannis to South Carolina

Keep the following information in mind while searching for Hyannis to South Carolina flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$919
(JetBlue)

One-way from

$228
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$179
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
Search Deals
From Hyannis Barnstable to South Carolina
Search Deals
One-way flight from Hyannis Barnstable to South Carolina
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Hyannis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Hyannis to South Carolina that are best for you.

Fly from

Hyannis

Fly to

South Carolina

Route

Depart

Return

Price

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Wed 12/31

7:05 am-11:36 am

1 stop4h 31m

Charleston

Sat 1/3

12:42 pm-5:20 pm

1 stop4h 38m

$919

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Mon 1/5

12:07 pm-1:10 pm

3 stops49h 03m

$228

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sun 1/4

12:07 pm-9:23 pm

2 stops33h 16m

$237

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Thu 1/1

7:05 am-11:36 am

1 stop4h 31m

$238

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 1/3

7:05 am-11:57 am

1 stop4h 52m

$243

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sun 1/4

7:05 am-12:23 pm

1 stop5h 18m

$278

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Mon 1/5

7:05 am-11:36 am

1 stop4h 31m

$278

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Thu 1/1

7:05 am-10:59 pm

3 stops15h 54m

$283

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 1/2

7:05 am-9:23 pm

2 stops14h 18m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Best time to book a flight from Hyannis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Hyannis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Hyannis to South Carolina

What is the cheapest month to book a flight from Hyannis to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Hyannis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Hyannis to South Carolina?

    Located just 1.0 mi from the city center, Hyannis Barnstable (HYA) is the airport most travelers will use when flying to South Carolina from Hyannis.

  • How long is the flight from Hyannis to South Carolina?

    JetBlue can get you from Hyannis to South Carolina in just under 4h 31m. Your travel time can differ by up to . The distance from Hyannis to South Carolina is about 808 mi.

  • Can I find deals for flights from Hyannis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Hyannis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Hyannis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Hyannis to South Carolina.

  • Can I find deals for business class flights from Hyannis to South Carolina?

    Yes. Cheapflights offers flight deals from Hyannis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Hyannis to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Hyannis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Miami flights
Boston to Fort Lauderdale flights
Boston to Orlando flights
Boston to Tampa flights
Boston to Los Angeles flights
Boston to Las Vegas flights
Boston to Dallas/Fort Worth flights
Boston to Denver flights
Boston to Fort Myers flights
Boston to San Francisco flights
Hartford to Orlando flights
Boston to West Palm Beach flights
Boston to O'Hare Intl flights
Boston to Atlanta flights
Boston to New Orleans flights
Boston to Seattle flights
Boston to Sky Harbor Intl flights
Boston to Hobby flights
Boston to Baltimore flights
Boston to Sarasota flights
Boston to Nashville flights
Hartford to Tampa flights
Hartford to Fort Lauderdale flights
Boston to Salt Lake City flights
Boston to George Bush Intcntl flights
Boston to Newark flights
Boston to Austin flights
Boston to Reagan-National flights
Boston to Charlotte flights
Boston to San Diego flights
Albany to Orlando flights
Boston to John F Kennedy Intl flights
Boston to LaGuardia flights
Hartford to West Palm Beach flights
Boston to Charleston flights
Boston to Jacksonville flights
Boston to Dulles Intl flights
Boston to Philadelphia flights
Boston to Key West flights
Boston to Raleigh flights
Boston to Honolulu flights
Hartford to Fort Myers flights
Boston to Ontario flights
Hartford to Miami flights
Boston to Savannah flights
Boston to Detroit flights
Boston to Love Field flights
Hartford to Denver flights
Boston to Minneapolis flights
Hartford to Dallas/Fort Worth flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.