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$343+ Cheap flights from Hyannis (HYA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
HYA — CHS
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
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Cheap flight deals from Hyannis to South Carolina

Keep the following information in mind while searching for Hyannis to South Carolina flight deals. Data was last updated November 18, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$550
(JetBlue)

One-way from

$343
(JetBlue)

Popular in

April

Cheapest in

February

Average price

$251
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
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From Hyannis Barnstable to South Carolina
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One-way flight from Hyannis Barnstable to South Carolina
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Highest demand for flights based on searches. 9% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Hyannis to South Carolina

Cheapest flights from Hyannis to South Carolina
Explore the most affordable flight options available from Hyannis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This JetBlue deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:58 amHYA - CHS
1 stop4h 54mJetBlue
Fri 11/2810:58 amCHS - HYA
1 stop7h 41mJetBlue
Deal found 11/18$630

Cheapflights Fare Finder

 
Customize your flight search to find flights from Hyannis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Hyannis to South Carolina that are best for you.

Fly from

Hyannis

Fly to

South Carolina

Route

Depart

Return

Price

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 3/27

12:07 pm-6:43 pm

1 stop6h 36m

Charleston

Sun 3/29

10:32 am-5:20 pm

1 stop6h 48m

$550

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 3/13

12:07 pm-6:43 pm

1 stop6h 36m

Charleston

Mon 3/16

10:32 am-5:20 pm

1 stop6h 48m

$615

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Mon 11/24

2:30 pm-7:55 pm

1 stop5h 25m

$343

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sun 11/23

7:58 am-12:52 pm

1 stop4h 54m

$343

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sun 11/30

12:07 pm-8:04 pm

1 stop7h 57m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Best time to book a flight from Hyannis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Hyannis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Hyannis to South Carolina

What is the cheapest month to book a flight from Hyannis to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Hyannis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Hyannis to South Carolina?

    Located just 1.0 mi from the city center, Hyannis Barnstable (HYA) is the airport most travelers will use when flying to South Carolina from Hyannis.

  • How long is the flight from Hyannis to South Carolina?

    JetBlue can get you from Hyannis to South Carolina in just under 6h 36m. Your travel time can differ by up to . The distance from Hyannis to South Carolina is about 808 mi.

  • Can I find deals for flights from Hyannis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Hyannis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Hyannis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Hyannis to South Carolina.

  • Can I find deals for business class flights from Hyannis to South Carolina?

    Yes. Cheapflights offers flight deals from Hyannis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Hyannis to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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