HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South Carolina

$530+ Cheap flights from Hyannis (HYA) to South Carolina

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
HYA — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Hyannis to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Hyannis to South Carolina

Cheapest flights from Hyannis to South Carolina
Explore the most affordable flight options available from Hyannis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This JetBlue deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/217:05 am
HYA
-
CHS
1 stop5h 13m
JetBlue
Wed 2/2510:20 am
CHS
-
HYA
1 stop7h 00m
JetBlue
Deal found 1/27$530

Find flight deals from Hyannis to South Carolina

Keep the following information in mind while searching for Hyannis to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$530
(JetBlue)

Popular in

December

Cheapest in

February

Average price

$167
Provider with most accurate pricing for Boston Logan Intl-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Myrtle Beach Intl flights.
Search Deals
From Hyannis Barnstable to South Carolina
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Hyannis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Hyannis to South Carolina that are best for you.

Fly from

Hyannis

Fly to

South Carolina

Route

Depart

Return

Price

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 2/21

7:05 am-12:18 pm

1 stop5h 13m

Charleston

Wed 2/25

10:20 am-5:20 pm

1 stop7h 00m

$530

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Wed 4/15

12:07 pm-8:34 pm

1 stop8h 27m

$538

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Wed 4/15

12:41 pm-8:34 pm

2 stops7h 53m

$578

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 4/10

12:07 pm-6:16 pm

1 stop6h 09m

$588

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 7/3

1:20 pm-8:20 pm

1 stop7h 00m

$641

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Hyannis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Hyannis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Hyannis to South Carolina

What is the cheapest month to book a flight from Hyannis to South Carolina?

Currently, March is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Hyannis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Hyannis to South Carolina?

    Located just 1.0 mi from the city center, Hyannis Barnstable (HYA) is the airport most travelers will use when flying to South Carolina from Hyannis.

  • How long is the flight from Hyannis to South Carolina?

    JetBlue can get you from Hyannis to South Carolina in just under 5h 13m. Your travel time can differ by up to . The distance from Hyannis to South Carolina is about 808 mi.

  • Can I find deals for flights from Hyannis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Hyannis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Hyannis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Hyannis to South Carolina.

  • Can I find deals for business class flights from Hyannis to South Carolina?

    Yes. Cheapflights offers flight deals from Hyannis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Hyannis to South Carolina?

    Currently, March is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $63). Flying from Hyannis to South Carolina in October is currently the most expensive (average of $108). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Hyannis to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Fort Lauderdale flights
Boston to Tampa flights
Boston to Miami flights
Boston to Orlando flights
Boston to San Francisco flights
Boston to West Palm Beach flights
Boston to Los Angeles flights
Boston to Las Vegas flights
Boston to Dallas/Fort Worth flights
Boston to Fort Myers flights
Boston to Sky Harbor Intl flights
Boston to Sarasota flights
Boston to Atlanta flights
Boston to Denver flights
Hartford to Orlando flights
Boston to Seattle flights
Boston to Nashville flights
Boston to Baltimore flights
Boston to New Orleans flights
Boston to Salt Lake City flights
Boston to Hobby flights
Boston to Charleston flights
Hartford to Tampa flights
Boston to O'Hare Intl flights
Boston to Austin flights
Boston to Reagan-National flights
Boston to Dulles Intl flights
Albany to Orlando flights
Boston to San Jose flights
Hartford to Fort Lauderdale flights
Boston to San Diego flights
Boston to George Bush Intcntl flights
Boston to Jacksonville flights
Boston to Savannah flights
Hartford to Fort Myers flights
Boston to Raleigh flights
Boston to John F Kennedy Intl flights
Hartford to Miami flights
Hartford to West Palm Beach flights
Boston to Charlotte flights
Boston to Key West flights
Boston to Philadelphia flights
Boston to Newark flights
Hartford to O'Hare Intl flights
Boston to Ontario flights
Boston to LaGuardia flights
Boston to Oakland flights
Boston to Pittsburgh flights
Boston to Myrtle Beach flights
Boston to Minneapolis flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.