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$229+ Cheap flights from Hyannis (HYA) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
HYA — CHS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Hyannis to South Carolina

Keep the following information in mind while searching for Hyannis to South Carolina flight deals. Data was last updated September 11, 2025.

Round-trip from

$534
(Kiwi.com)

One-way from

$229
(JetBlue)

Popular in

April

Cheapest in

February

Average price

$197
From Hyannis Barnstable to South Carolina
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One-way flight from Hyannis Barnstable to South Carolina
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Highest demand for flights based on searches. 13% potential increase in price ($28 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Hyannis to South Carolina

Cheapest flights from Hyannis to South Carolina
Explore the most affordable flight options available from Hyannis to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2510:29 amHYA - CLT
1 stop11h 08mMultiple Airlines
Mon 9/295:36 pmCLT - HYA
2 stops21h 34mMultiple Airlines
Deal found 9/10$534
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:48 amHYA - CHS
1 stop5h 49mJetBlue
Tue 9/238:00 amCHS - HYA
1 stop9h 38mJetBlue
Deal found 9/10$540
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/263:50 pmHYA - CLT
1 stop25h 04mMultiple Airlines
Sun 11/210:19 amCLT - HYA
2 stops9h 33mMultiple Airlines
Deal found 9/11$681
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2210:29 amHYA - CLT
1 stop11h 08mMultiple Airlines
Tue 9/2310:46 amCLT - HYA
2 stops25h 20mMultiple Airlines
Deal found 9/11$690

Cheapflights Fare Finder

 
Customize your flight search to find flights from Hyannis to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Hyannis to South Carolina that are best for you.

Fly from

Hyannis

Fly to

South Carolina

Route

Depart

Return

Price

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Thu 9/25

10:29 am-9:37 pm

1 stop11h 08m

Charlotte Douglas

Mon 9/29

5:36 pm-3:10 pm

2 stops21h 34m

$534

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Sun 10/26

3:50 pm-4:54 pm

1 stop25h 04m

Charlotte Douglas

Sun 11/2

10:19 am-7:52 pm

2 stops9h 33m

$681

HyannisCharlotte

HYA - CLT

HYACLT

Hyannis Barnstable

Mon 9/22

10:29 am-9:37 pm

1 stop11h 08m

Charlotte Douglas

Tue 9/23

10:46 am-12:06 pm

2 stops25h 20m

$690

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Sat 2/28

2:03 pm-8:44 pm

1 stop6h 41m

Charleston

Tue 3/3

9:30 am-2:40 pm

1 stop5h 10m

$755

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Mon 9/22

10:16 am-5:45 pm

1 stop7h 29m

$229

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Thu 10/23

11:25 am-4:14 pm

1 stop4h 49m

$368

HyannisCharleston

HYA - CHS

HYACHS

Hyannis Barnstable

Fri 11/7

11:00 am-6:40 pm

1 stop7h 40m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Hyannis to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Hyannis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Hyannis to South Carolina

What is the cheapest month to book a flight from Hyannis to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $217). Flying from Hyannis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Hyannis to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Hyannis to South Carolina?

    Located just 1.0 mi from the city center, Hyannis Barnstable (HYA) is the airport most travelers will use when flying to South Carolina from Hyannis.

  • How long is the flight from Hyannis to South Carolina?

    JetBlue can get you from Hyannis to South Carolina in just under 6h 41m. Your travel time can differ by up to . The distance from Hyannis to South Carolina is about 808 mi.

  • Can I find deals for flights from Hyannis to South Carolina that include hotel bookings?

    Yes. In addition to deals on Hyannis to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Hyannis to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Hyannis to South Carolina.

  • Can I find deals for business class flights from Hyannis to South Carolina?

    Yes. Cheapflights offers flight deals from Hyannis to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Hyannis to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Hyannis to South Carolina (average of $217). Flying from Hyannis to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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