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$181+ Cheap flights from Harlingen, TX (HRL) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
HRL — CHS
Nov 21 — Nov 281
Fri 11/21
Fri 11/28
1 adult, Economy
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Cheap flight deals from Harlingen to South Carolina

Keep the following information in mind while searching for Harlingen to South Carolina flight deals. Data was last updated October 22, 2025.

Round-trip from

$291
(American Airlines)

One-way from

$181
(American Airlines)
From Harlingen Valley Intl to South Carolina
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One-way flight from Harlingen Valley Intl to South Carolina
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Find flight deals from Harlingen to South Carolina

Cheapest flights from Harlingen to South Carolina
Explore the most affordable flight options available from Harlingen to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 22, 2025.

This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:30 amHRL - SAV
1 stop6h 45mSouthwest
Mon 1/510:55 amSAV - HRL
2 stops9h 30mSouthwest
Deal found 10/20$375
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:08 pmHRL - GSP
1 stop7h 16mAmerican Airlines
Wed 12/36:00 amGSP - HRL
1 stop6h 40mAmerican Airlines
Deal found 10/20$418
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:08 pmHRL - GSP
1 stop6h 47mAmerican Airlines
Wed 12/36:00 amGSP - HRL
1 stop6h 40mAmerican Airlines
Deal found 10/20$444
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/254:08 pmHRL - GSP
1 stop6h 47mAmerican Airlines
Wed 12/36:00 amGSP - HRL
1 stop6h 40mAmerican Airlines
Deal found 10/20$468
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:48 pmHRL - SAV
1 stop6h 20mAmerican Airlines
Mon 1/57:00 amSAV - HRL
1 stop8h 18mAmerican Airlines
Deal found 10/20$479
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/213:40 pmHRL - SAV
2 stops6h 40mSouthwest
Mon 12/293:25 pmSAV - HRL
2 stops9h 30mSouthwest
Deal found 10/21$488
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:08 pmHRL - GSP
1 stop7h 16mAmerican Airlines
Tue 12/24:48 pmGSP - HRL
1 stop7h 22mAmerican Airlines
Deal found 10/20$499
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/203:39 pmHRL - GSP
2 stops16h 23mDelta
Wed 12/35:17 pmGSP - HRL
2 stops22h 29mDelta
Deal found 10/20$503
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/237:00 amHRL - GSP
1 stop7h 39mUnited Airlines
Wed 12/310:00 amGSP - HRL
2 stops10h 49mUnited Airlines
Deal found 10/20$504
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/204:08 pmHRL - GSP
1 stop6h 47mAmerican Airlines
Tue 12/24:48 pmGSP - HRL
1 stop7h 22mAmerican Airlines
Deal found 10/20$525
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/214:08 pmHRL - GSP
1 stop6h 47mAmerican Airlines
Wed 12/36:00 amGSP - HRL
1 stop6h 40mAmerican Airlines
Deal found 10/20$538
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:11 pmHRL - SAV
1 stop21h 36mAmerican Airlines
Mon 12/297:00 amSAV - HRL
1 stop13h 16mAmerican Airlines
Deal found 10/21$539

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harlingen to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 22, 2025.
Use the filters below to find and compare flights from Harlingen to South Carolina that are best for you.

Fly from

Harlingen

Fly to

South Carolina

Route

Depart

Return

Price

HarlingenGreenville

HRL - GSP

HRLGSP

Harlingen Valley Intl

Tue 3/3

10:05 am-5:33 pm

1 stop6h 28m

Greenville

Wed 3/4

7:53 pm-12:01 am

1 stop5h 08m

$291

HarlingenGreenville

HRL - GSP

HRLGSP

Harlingen Valley Intl

Tue 3/3

9:20 am-11:59 pm

2 stops13h 39m

Greenville

Wed 3/4

6:50 am-11:24 am

1 stop5h 34m

$296

HarlingenSavannah

HRL - SAV

HRLSAV

Harlingen Valley Intl

Tue 2/24

12:10 pm-6:06 pm

1 stop4h 56m

Savannah/Hilton Head

Sat 2/28

3:28 pm-9:59 pm

1 stop7h 31m

$346

HarlingenSavannah

HRL - SAV

HRLSAV

Harlingen Valley Intl

Wed 12/31

10:30 am-6:15 pm

1 stop6h 45m

Savannah/Hilton Head

Mon 1/5

10:55 am-7:25 pm

2 stops9h 30m

$375

HarlingenSavannah

HRL - SAV

HRLSAV

Harlingen Valley Intl

Tue 2/24

5:50 am-5:16 pm

2 stops10h 26m

Savannah/Hilton Head

Sat 2/28

12:38 pm-12:01 am

2 stops12h 23m

$399

HarlingenGreenville

HRL - GSP

HRLGSP

Harlingen Valley Intl

Mon 11/24

4:08 pm-12:24 am

1 stop7h 16m

Greenville

Wed 12/3

6:00 am-11:40 am

1 stop6h 40m

$418

HarlingenGreenville

HRL - GSP

HRLGSP

Harlingen Valley Intl

Thu 11/20

4:08 pm-11:55 pm

1 stop6h 47m

Greenville

Wed 12/3

6:00 am-11:40 am

1 stop6h 40m

$444

HarlingenGreenville

HRL - GSP

HRLGSP

Harlingen Valley Intl

Tue 11/25

4:08 pm-11:55 pm

1 stop6h 47m

Greenville

Wed 12/3

6:00 am-11:40 am

1 stop6h 40m

$468

HarlingenSavannah

HRL - SAV

HRLSAV

Harlingen Valley Intl

Wed 12/31

2:48 pm-10:08 pm

1 stop6h 20m

Savannah/Hilton Head

Mon 1/5

7:00 am-2:18 pm

1 stop8h 18m

$479

HarlingenSavannah

HRL - SAV

HRLSAV

Harlingen Valley Intl

Mon 11/24

12:11 pm-11:59 pm

2 stops10h 48m

$181

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/19

Showing 1-10 of 11 results
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Best time to book a flight from Harlingen to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Harlingen with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harlingen to South Carolina

What is the cheapest time of day to fly from HRL to SC?

Find hourly flight availability from Harlingen to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 22, 2025.

When flying from Harlingen, Texas to South Carolina, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 57% versus a flight in the evening.

Related info for your journey

Find useful and relevant information for your journey from Harlingen to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harlingen to South Carolina?

    Harlingen Valley Intl (HRL) is the airport you will fly out of if you book a flight from Harlingen to South Carolina. It is only a 3.7 mi journey to Valley Intl (HRL) from Harlingen’s city center.

  • How long is the flight from Harlingen, Texas to South Carolina?

    There are many flights that can get you from Harlingen, Texas to South Carolina in 6h 28m. Fly via American Airlines or United Airlines to get the fastest option. The distance between Harlingen, Texas and South Carolina is about 1093 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Harlingen to South Carolina that include hotel bookings?

    Yes. In addition to deals on Harlingen to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harlingen to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harlingen to South Carolina.

  • Can I find deals for business class flights from Harlingen to South Carolina?

    Yes. Cheapflights offers flight deals from Harlingen to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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