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South Carolina

$155+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
feb. 20 — feb. 271
vie. 2/20
vie. 2/27
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This Trip.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/51:26 am
GYE
-
CLT
1 stop19h 32m
Multiple Airlines
dom. 2/158:46 am
CLT
-
GYE
1 stop15h 18m
Multiple Airlines
Deal found 1/20$260
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/1311:59 pm
GYE
-
MYR
1 stop16h 40m
Spirit Airlines
jue. 4/237:51 pm
MYR
-
GYE
1 stop28h 10m
Spirit Airlines
Deal found 1/21$277
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/911:59 pm
GYE
-
MYR
1 stop31h 14m
Spirit Airlines
jue. 3/196:37 pm
MYR
-
GYE
1 stop29h 27m
Spirit Airlines
Deal found 1/21$281
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/2411:59 pm
GYE
-
MYR
1 stop16h 40m
Spirit Airlines
mar. 3/316:37 pm
MYR
-
GYE
1 stop29h 27m
Spirit Airlines
Deal found 1/20$288
This Orbitz deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/51:26 am
GYE
-
CLT
2 stops15h 28m
Spirit Airlines
dom. 2/155:55 am
CLT
-
GYE
1 stop18h 09m
Spirit Airlines
Deal found 1/20$293
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/2612:59 am
GYE
-
CLT
1 stop17h 19m
Spirit Airlines
mar. 3/101:24 pm
CLT
-
GYE
1 stop10h 40m
Spirit Airlines
Deal found 1/21$294
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/2211:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
sáb. 5/96:00 am
CLT
-
GYE
1 stop18h 01m
Spirit Airlines
Deal found 1/21$296
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 2/2812:59 am
GYE
-
CHS
1 stop16h 41m
Spirit Airlines
vie. 3/138:07 am
CHS
-
GYE
1 stop15h 57m
Spirit Airlines
Deal found 1/20$302
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/111:59 pm
GYE
-
CLT
1 stop19h 24m
Spirit Airlines
dom. 4/129:22 pm
CLT
-
GYE
1 stop26h 42m
Spirit Airlines
Deal found 1/21$304
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/304:00 pm
GYE
-
CHS
1 stop18h 00m
Delta
mar. 11/32:30 pm
CHS
-
GYE
1 stop17h 25m
Delta
Deal found 1/20$306
This Priceline deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/2411:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
sáb. 8/298:59 am
CLT
-
GYE
1 stop15h 02m
Spirit Airlines
Deal found 1/21$318
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 2/106:55 pm
GYE
-
CLT
2 stops41h 11m
Multiple Airlines
sáb. 2/281:24 pm
CLT
-
GYE
1 stop10h 40m
Multiple Airlines
Deal found 1/20$324

Find flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated enero 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$260
(Trip.com)

One-way from

$155
(Cheapflightsfares)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

jue. 2/5

1:26 am-8:58 pm

1 stop19h 32m

Charlotte Douglas

dom. 2/15

8:46 am-12:04 am

1 stop15h 18m

$260

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

lun. 3/9

11:59 pm-8:13 am

1 stop31h 14m

Myrtle Beach Intl

jue. 3/19

6:37 pm-11:04 pm

1 stop29h 27m

$281

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

mar. 3/24

11:59 pm-5:39 pm

1 stop16h 40m

Myrtle Beach Intl

mar. 3/31

6:37 pm-11:04 pm

1 stop29h 27m

$288

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

jue. 2/26

12:59 am-6:18 pm

1 stop17h 19m

Charlotte Douglas

mar. 3/10

1:24 pm-11:04 pm

1 stop10h 40m

$294

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

lun. 4/13

11:59 pm-5:39 pm

1 stop16h 40m

Myrtle Beach Intl

jue. 4/23

7:51 pm-11:01 pm

1 stop28h 10m

$296

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

vie. 5/1

11:59 pm-2:13 pm

1 stop13h 14m

Charlotte Douglas

mar. 5/26

6:00 am-11:01 pm

1 stop18h 01m

$296

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

mié. 4/1

11:59 pm-8:23 pm

1 stop19h 24m

Charlotte Douglas

dom. 4/12

9:22 pm-11:04 pm

1 stop26h 42m

$304

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

jue. 2/26

6:55 pm-8:26 am

2 stops37h 31m

Charlotte Douglas

lun. 3/2

6:47 pm-12:04 am

1 stop29h 17m

$309

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

jue. 2/5

1:26 am-6:48 pm

1 stop17h 22m

Charlotte Douglas

dom. 2/15

11:12 am-12:04 am

2 stops12h 52m

$317

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

mar. 2/10

6:55 pm-12:06 pm

2 stops41h 11m

Charlotte Douglas

sáb. 2/28

1:24 pm-12:04 am

1 stop10h 40m

$324

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 46 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 21h 44m. Fly via Spirit Airlines or JetBlue to get the fastest option. The distance between Guayaquil and South Carolina is about 2420 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo - Charleston.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

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