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$145+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/8. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:26 am
GYE
-
CLT
1 stop19h 32m
Multiple Airlines
Sun 2/158:46 am
CLT
-
GYE
1 stop15h 18m
Multiple Airlines
Deal found 1/28$234
This Mytrip deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Thu 4/308:55 am
CLT
-
GYE
1 stop15h 06m
Spirit Airlines
Deal found 1/26$271
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:26 am
GYE
-
CHS
1 stop16h 13m
Spirit Airlines
Thu 2/196:35 pm
CHS
-
GYE
1 stop29h 29m
Spirit Airlines
Deal found 1/28$273
This Priceline deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1311:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Wed 5/208:55 am
CLT
-
GYE
1 stop15h 06m
Spirit Airlines
Deal found 1/27$280
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:26 am
GYE
-
CLT
1 stop23h 14m
Spirit Airlines
Sun 2/1511:12 am
CLT
-
GYE
2 stops12h 52m
Spirit Airlines
Deal found 1/28$282
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1011:59 pm
GYE
-
CLT
1 stop22h 57m
Spirit Airlines
Fri 3/201:24 pm
CLT
-
GYE
1 stop10h 40m
Spirit Airlines
Deal found 1/27$283
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Sat 4/258:55 am
CLT
-
GYE
1 stop15h 06m
Spirit Airlines
Deal found 1/27$292
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/41:26 am
GYE
-
CHS
1 stop16h 13m
Multiple Airlines
Wed 2/1812:03 pm
CHS
-
GYE
1 stop19h 52m
Multiple Airlines
Deal found 1/28$304
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1511:59 pm
GYE
-
MYR
1 stop16h 40m
Spirit Airlines
Sun 3/226:37 pm
MYR
-
GYE
1 stop29h 27m
Spirit Airlines
Deal found 1/28$307
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:05 pm
GYE
-
CLT
1 stop20h 25m
Multiple Airlines
Sat 2/287:13 pm
CLT
-
GYE
1 stop28h 51m
Multiple Airlines
Deal found 1/27$307
This Mytrip deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/41:26 am
GYE
-
CHS
1 stop16h 13m
Spirit Airlines
Wed 2/185:00 pm
CHS
-
GYE
2 stops31h 04m
Spirit Airlines
Deal found 1/28$315
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:00 pm
GYE
-
CHS
2 stops18h 26m
Delta
Tue 11/310:30 am
CHS
-
GYE
2 stops21h 25m
Delta
Deal found 1/27$318

Find flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$271
(Mytrip)

One-way from

$145
(Cheapflightsfares)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 5/20

11:59 pm-2:13 pm

1 stop13h 14m

Charlotte Douglas

Sun 5/31

8:55 am-11:01 pm

1 stop15h 06m

$292

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 3/10

11:59 pm-11:56 pm

1 stop22h 57m

Charlotte Douglas

Fri 3/20

1:24 pm-11:04 pm

1 stop10h 40m

$302

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 3/3

12:59 am-4:54 pm

2 stops15h 55m

Charlotte Douglas

Wed 3/11

11:12 am-11:04 pm

2 stops12h 52m

$309

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sat 2/28

6:55 pm-8:26 am

2 stops37h 31m

Charlotte Douglas

Tue 3/24

8:56 am-11:04 pm

1 stop15h 08m

$312

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Tue 3/3

4:30 pm-11:18 am

1 stop18h 48m

Charleston

Tue 5/12

5:25 pm-6:55 am

1 stop14h 30m

$318

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sat 4/25

11:59 pm-8:26 am

1 stop31h 27m

Charlotte Douglas

Sat 5/9

3:08 pm-5:20 pm

2 stops27h 12m

$326

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Fri 3/20

11:59 pm-8:23 pm

1 stop19h 24m

Charlotte Douglas

Fri 4/3

9:22 pm-11:04 pm

1 stop26h 42m

$334

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 2/26

8:34 am-11:56 pm

2 stops15h 22m

Charlotte Douglas

Sat 2/28

7:13 pm-12:04 am

1 stop28h 51m

$339

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Sun 3/15

11:59 pm-5:39 pm

1 stop16h 40m

Myrtle Beach Intl

Sun 3/22

12:05 pm-11:04 pm

2 stops35h 59m

$342

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

11:59 pm-9:42 am

1 stop8h 43m

Myrtle Beach Intl

Mon 5/25

7:51 pm-11:01 pm

1 stop28h 10m

$348

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 44 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 13h 14m. Fly via Spirit Airlines, Delta, or LATAM Airlines to get the fastest option. The distance between Guayaquil and South Carolina is about 2582 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo - Charleston.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

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