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South Carolina

$209+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated October 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$333
(American Airlines)

One-way from

$209
(Avianca Connect)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to South Carolina
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One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
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Find flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:05 pmGYE - CLT
1 stop12h 42mMultiple Airlines
Tue 11/117:59 pmCLT - GYE
2 stops13h 16mMultiple Airlines
Deal found 10/13$379
This SmartFares deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:31 pmGYE - CHS
1 stop16h 06mJetBlue
Wed 1/1411:35 amCHS - GYE
1 stop27h 45mJetBlue
Deal found 10/13$422
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:05 pmGYE - CLT
1 stop26h 52mMultiple Airlines
Mon 11/1710:07 amCLT - GYE
2 stops13h 34mMultiple Airlines
Deal found 10/13$426
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:05 pmGYE - CLT
1 stop12h 42mMultiple Airlines
Sat 11/156:44 pmCLT - GYE
2 stops28h 57mMultiple Airlines
Deal found 10/12$455
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:05 pmGYE - CLT
1 stop13h 44mMultiple Airlines
Sun 11/237:30 amCLT - GYE
2 stops27h 48mMultiple Airlines
Deal found 10/12$477
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:40 amGYE - CLT
2 stops11h 15mMultiple Airlines
Sun 11/1610:42 pmCLT - GYE
1 stop30h 38mMultiple Airlines
Deal found 10/12$484
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:50 pmGYE - CLT
1 stop12h 57mMultiple Airlines
Sun 12/141:57 pmCLT - GYE
2 stops19h 18mMultiple Airlines
Deal found 10/13$537
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:30 pmGYE - CLT
1 stop18h 19mDelta
Wed 1/1411:45 amCLT - GYE
2 stops19h 35mDelta
Deal found 10/12$543
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:55 pmGYE - CLT
2 stops37h 10mMultiple Airlines
Sun 11/910:42 pmCLT - GYE
1 stop30h 38mMultiple Airlines
Deal found 10/12$555
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:15 amGYE - CHS
2 stops11h 28mAmerican Airlines
Wed 11/59:22 amCHS - GYE
1 stop13h 44mAmerican Airlines
Deal found 10/14$663
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amGYE - CHS
1 stop26h 42mAmerican Airlines
Sat 11/157:00 amCHS - GYE
2 stops16h 06mAmerican Airlines
Deal found 10/13$685
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:30 amGYE - CHS
2 stops37h 29mUnited Airlines
Sat 11/155:05 pmCHS - GYE
2 stops30h 36mUnited Airlines
Deal found 10/14$698

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Tue 3/3

2:33 pm-10:05 am

2 stops19h 32m

Charleston

Tue 5/12

8:08 pm-1:33 pm

1 stop18h 25m

$333

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 11/6

7:05 pm-7:47 am

1 stop12h 42m

Charlotte Douglas

Tue 11/11

7:59 pm-9:15 am

2 stops13h 16m

$379

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Tue 12/16

4:31 pm-8:37 am

1 stop16h 06m

Charleston

Wed 1/14

11:35 am-3:20 pm

1 stop27h 45m

$422

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

12:59 am-10:41 am

1 stop9h 42m

Myrtle Beach Intl

Tue 2/10

11:46 am-11:45 pm

1 stop11h 59m

$435

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

12:59 am-8:37 am

2 stops31h 38m

Charlotte Douglas

Wed 1/28

5:45 am-11:45 pm

1 stop18h 00m

$442

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 2/10

12:59 am-9:06 pm

2 stops20h 07m

Charlotte Douglas

Fri 2/20

10:11 pm-11:45 pm

2 stops25h 34m

$488

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 2/11

6:50 pm-4:01 pm

1 stop21h 11m

Charlotte Douglas

Fri 2/20

10:32 am-5:20 am

1 stop18h 48m

$515

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Mon 3/2

2:33 pm-11:29 pm

1 stop8h 56m

Charleston

Tue 5/12

8:08 pm-1:33 pm

1 stop18h 25m

$523

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Mon 3/2

2:33 pm-10:05 am

2 stops19h 32m

Charleston

Sun 3/15

8:44 pm-1:33 pm

2 stops17h 49m

$528

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Sat 2/28

2:33 pm-10:17 am

1 stop19h 44m

Charleston

Fri 5/15

8:44 pm-1:33 pm

2 stops17h 49m

$536

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 34 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina

What is the cheapest month to book a flight from Guayaquil to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SC?

Find hourly flight availability from Guayaquil to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 64% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 14, 2025.
Peruse reviews from past customers who have flown with Spirit Airlines from Guayaquil to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Spirit Airlines
6.3
Okay
8,096 reviews

Entertainment

5.0

Overall

6.3

Crew

7.0

Food

5.1

Boarding

6.6

Comfort

5.9

Reviews

1 / 20
6.0
Good

Anonymous,Oct 2025

MCO - PIT

Did not get anything for free no snacks or drinks
Spirit Airlines
6.3
Okay
8,096 reviews
Spirit Airlines
6.3
Okay
8,096 reviews

Entertainment

5.0

Overall

6.3

Crew

7.0

Food

5.1

Boarding

6.6

Comfort

5.9

Reviews

1 / 20
6.0
Good

Anonymous,Oct 2025

MCO - PIT

Did not get anything for free no snacks or drinks

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 9h 42m. Fly via American Airlines, JetBlue, or Spirit Airlines to get the fastest option. The distance between Guayaquil and South Carolina is about 2475 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Charleston and Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Guayaquil to South Carolina

Discover the top airline that operate flights from Guayaquil to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$320Average$444FlexibilityNo cancel feeOn-time65%

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