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$200+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$324
(Delta)

One-way from

$200
(Avianca Connect)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to South Carolina
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One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
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Find flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Priceline deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2512:49 amGYE - MYR
1 stop17h 19mSpirit Airlines
Mon 1/2611:46 amMYR - GYE
1 stop11h 59mSpirit Airlines
Deal found 10/28$364
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 pmGYE - CLT
1 stop25h 04mMultiple Airlines
Mon 1/1210:11 pmCLT - GYE
2 stops25h 34mMultiple Airlines
Deal found 10/27$389
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:49 amGYE - CLT
1 stop13h 14mSpirit Airlines
Thu 1/225:45 amCLT - GYE
3 stops18h 00mSpirit Airlines
Deal found 10/28$390
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:49 amGYE - CLT
2 stops19h 11mSpirit Airlines
Sun 12/78:55 pmCLT - GYE
2 stops26h 48mSpirit Airlines
Deal found 10/28$393
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:50 pmGYE - CLT
1 stop24h 20mMultiple Airlines
Wed 12/312:51 pmCLT - GYE
2 stops33h 02mMultiple Airlines
Deal found 10/27$398
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:05 pmGYE - CLT
1 stop17h 55mMultiple Airlines
Tue 11/2510:13 amCLT - GYE
2 stops25h 05mMultiple Airlines
Deal found 10/28$400
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/36:55 pmGYE - CLT
2 stops38h 07mMultiple Airlines
Mon 11/1010:42 pmCLT - GYE
1 stop30h 53mMultiple Airlines
Deal found 10/29$402
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:50 pmGYE - CLT
1 stop18h 10mMultiple Airlines
Tue 11/2510:13 amCLT - GYE
2 stops25h 05mMultiple Airlines
Deal found 10/28$404
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:49 amGYE - CLT
2 stops19h 50mSpirit Airlines
Tue 1/69:00 amCLT - GYE
1 stop14h 53mSpirit Airlines
Deal found 10/28$414
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:50 pmGYE - CLT
1 stop13h 59mMultiple Airlines
Mon 12/15:59 pmCLT - GYE
2 stops50h 26mMultiple Airlines
Deal found 10/29$418
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:50 pmGYE - CLT
2 stops24h 54mMultiple Airlines
Sat 12/62:57 pmCLT - GYE
1 stop8h 46mMultiple Airlines
Deal found 10/28$419
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:50 pmGYE - MYR
2 stops53h 09mMultiple Airlines
Mon 1/2611:46 amMYR - GYE
1 stop11h 59mMultiple Airlines
Deal found 10/28$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Fri 4/24

4:00 pm-11:46 am

1 stop18h 46m

Charleston

Tue 4/28

5:25 pm-7:20 am

1 stop14h 55m

$324

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Thu 12/25

12:49 am-6:08 pm

1 stop17h 19m

Myrtle Beach Intl

Mon 1/26

11:46 am-11:45 pm

1 stop11h 59m

$364

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

12:59 am-10:41 am

1 stop9h 42m

Myrtle Beach Intl

Tue 2/10

11:46 am-11:45 pm

1 stop11h 59m

$401

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Mon 11/17

6:50 pm-1:00 pm

1 stop18h 10m

Charlotte Douglas

Tue 11/25

3:01 pm-5:35 am

1 stop14h 34m

$456

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Fri 12/26

12:49 am-9:39 am

1 stop8h 50m

Charlotte Douglas

Tue 2/17

10:11 pm-11:45 pm

2 stops25h 34m

$457

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Fri 4/24

2:33 pm-10:17 am

1 stop18h 44m

Charleston

Tue 4/28

6:40 pm-1:33 pm

2 stops19h 53m

$460

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Mon 11/24

6:00 am-8:49 am

2 stops26h 49m

Charlotte Douglas

Mon 12/1

3:01 pm-9:18 am

2 stops18h 17m

$460

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sun 12/21

12:49 am-8:39 pm

2 stops19h 50m

Charlotte Douglas

Tue 1/6

9:34 pm-11:53 pm

2 stops26h 19m

$472

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 11/18

7:05 pm-1:00 pm

1 stop17h 55m

Charlotte Douglas

Tue 11/25

3:01 pm-5:35 am

1 stop14h 34m

$485

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Mon 11/17

6:50 pm-1:00 pm

1 stop18h 10m

Charlotte Douglas

Fri 11/21

3:01 pm-5:20 am

1 stop14h 19m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 24 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina

What is the cheapest month to book a flight from Guayaquil to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SC?

Find hourly flight availability from Guayaquil to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 64% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Spirit Airlines from Guayaquil to South Carolina to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Spirit Airlines
6.3
Okay
8,116 reviews

Overall

6.3

Boarding

6.6

Comfort

5.9

Crew

7.0

Food

5.1

Entertainment

5.0

Reviews

1 / 20
6.0
Good

Anonymous,Oct 2025

MCO - PIT

Did not get anything for free no snacks or drinks
Spirit Airlines
6.3
Okay
8,116 reviews
Spirit Airlines
6.3
Okay
8,116 reviews

Overall

6.3

Boarding

6.6

Comfort

5.9

Crew

7.0

Food

5.1

Entertainment

5.0

Reviews

1 / 20
6.0
Good

Anonymous,Oct 2025

MCO - PIT

Did not get anything for free no snacks or drinks

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 17h 19m. Fly via Delta, Spirit Airlines, or American Airlines to get the fastest option. The distance between Guayaquil and South Carolina is about 2475 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Charleston and Guayaquil Jose Joaquin de Olmedo - Florence.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Guayaquil to South Carolina

Discover the top airline that operate flights from Guayaquil to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$320Average$444FlexibilityNo cancel feeOn-time65%

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