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$141+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Feb 6 — Feb 131
Fri 2/6
Fri 2/13
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated January 7, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$283
(Kiwi.com)

One-way from

$141
(CheapOair)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to South Carolina
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One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
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Find flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 7, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/241:26 amGYE - CLT
1 stop30h 45mMultiple Airlines
Mon 2/25:24 pmCLT - GYE
1 stop30h 57mMultiple Airlines
Deal found 1/6$285
This Trip.com deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/281:26 amGYE - CLT
1 stop17h 22mSpirit Airlines
Tue 2/175:55 amCLT - GYE
1 stop18h 09mSpirit Airlines
Deal found 1/5$287
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/241:26 amGYE - CLT
1 stop30h 45mSpirit Airlines
Tue 2/36:00 amCLT - GYE
1 stop18h 21mSpirit Airlines
Deal found 1/6$288
This CheapOair deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:59 amGYE - CLT
2 stops15h 55mSpirit Airlines
Mon 3/25:55 amCLT - GYE
1 stop18h 09mSpirit Airlines
Deal found 1/5$296
This Mytrip deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:59 amGYE - CLT
1 stop17h 19mSpirit Airlines
Mon 3/166:00 amCLT - GYE
1 stop18h 18mSpirit Airlines
Deal found 1/7$301
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:50 pmGYE - CLT
1 stop22h 46mMultiple Airlines
Sun 2/228:46 amCLT - GYE
1 stop15h 18mMultiple Airlines
Deal found 1/7$302
This CheapOair deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/271:26 amGYE - CLT
2 stops15h 28mSpirit Airlines
Sun 2/86:00 amCLT - GYE
1 stop18h 21mSpirit Airlines
Deal found 1/6$311
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/241:26 amGYE - CLT
1 stop30h 45mMultiple Airlines
Tue 2/311:35 amCLT - GYE
2 stops12h 46mMultiple Airlines
Deal found 1/6$312
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:59 amGYE - MYR
1 stop14h 44mMultiple Airlines
Tue 5/127:51 pmMYR - GYE
1 stop28h 10mMultiple Airlines
Deal found 1/6$321
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1612:59 amGYE - MYR
1 stop31h 14mSpirit Airlines
Mon 5/117:51 pmMYR - GYE
1 stop28h 10mSpirit Airlines
Deal found 1/6$323
This Kiwi.com deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1412:59 amGYE - MYR
2 stops13h 56mSpirit Airlines
Sun 2/229:09 amMYR - GYE
1 stop14h 55mSpirit Airlines
Deal found 1/7$355
This oojo deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/81:26 amGYE - MYR
1 stop17h 54mSpirit Airlines
Mon 5/47:51 pmMYR - GYE
1 stop28h 10mSpirit Airlines
Deal found 1/6$370

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 7, 2026.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

12:59 am-3:43 pm

1 stop14h 44m

Myrtle Beach Intl

Tue 5/12

7:51 pm-11:01 pm

1 stop28h 10m

$321

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Mon 2/16

12:59 am-8:13 am

1 stop31h 14m

Myrtle Beach Intl

Mon 5/11

7:51 pm-11:01 pm

1 stop28h 10m

$323

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 2/19

12:59 am-6:18 pm

1 stop17h 19m

Charlotte Douglas

Fri 3/20

1:24 pm-11:18 pm

1 stop10h 54m

$323

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sat 1/31

1:26 am-9:47 pm

1 stop20h 21m

Charlotte Douglas

Sun 4/26

3:08 pm-1:40 pm

2 stops23h 32m

$332

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 2/26

12:59 am-6:18 pm

1 stop17h 19m

Charlotte Douglas

Tue 3/10

5:55 am-11:04 pm

1 stop18h 09m

$337

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 3/3

12:59 am-11:56 pm

1 stop22h 57m

Charlotte Douglas

Tue 3/17

7:00 am-9:15 am

2 stops27h 15m

$338

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Fri 2/27

12:59 am-11:59 pm

3 stops23h 00m

Charlotte Douglas

Mon 3/16

6:00 am-11:18 pm

1 stop18h 18m

$351

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Fri 2/20

8:34 am-11:56 pm

2 stops15h 22m

Charlotte Douglas

Fri 2/27

1:24 pm-12:04 am

1 stop10h 40m

$351

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Sun 2/8

1:26 am-7:20 pm

1 stop17h 54m

Myrtle Beach Intl

Mon 5/4

7:51 pm-11:01 pm

1 stop28h 10m

$370

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Thu 2/12

12:59 am-5:40 pm

1 stop16h 41m

Charleston

Sat 5/16

8:00 pm-10:58 am

1 stop15h 58m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Showing 1-10 of 47 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 21h 12m. Fly via Spirit Airlines or GOL to get the fastest option. The distance between Guayaquil and South Carolina is about 2420 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Charleston and Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

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