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$185+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Jan 4 — Jan 111
Sun 1/4
Sun 1/11
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2812:49 amGYE - CLT
2 stops19h 50mSpirit Airlines
Tue 1/136:00 amCLT - GYE
1 stop18h 21mSpirit Airlines
Deal found 12/2$278
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:49 amGYE - CLT
2 stops19h 11mSpirit Airlines
Sat 1/106:00 amCLT - GYE
1 stop18h 21mSpirit Airlines
Deal found 12/2$348
This CheapOair deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2712:49 amGYE - CLT
2 stops19h 50mSpirit Airlines
Mon 1/1211:12 amCLT - GYE
2 stops13h 09mSpirit Airlines
Deal found 12/5$365
This KAYAK deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:49 amGYE - CLT
1 stop8h 50mSpirit Airlines
Wed 1/146:00 amCLT - GYE
1 stop18h 21mSpirit Airlines
Deal found 12/5$370
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2112:49 amGYE - CLT
1 stop13h 23mMultiple Airlines
Sun 1/183:00 pmCLT - GYE
1 stop14h 20mMultiple Airlines
Deal found 12/2$385
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:49 amGYE - MYR
1 stop16h 59mMultiple Airlines
Mon 12/2210:40 amMYR - GYE
2 stops37h 13mMultiple Airlines
Deal found 12/2$511
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:49 amGYE - MYR
1 stop16h 59mSpirit Airlines
Sun 12/219:54 amMYR - GYE
1 stop13h 59mSpirit Airlines
Deal found 12/2$584
This Cheapflightsfares deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:49 amGYE - MYR
1 stop16h 59mSpirit Airlines
Mon 12/229:54 amMYR - GYE
1 stop13h 59mSpirit Airlines
Deal found 12/3$598
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:49 amGYE - MYR
2 stops18h 43mSpirit Airlines
Tue 12/99:54 amMYR - GYE
1 stop13h 49mSpirit Airlines
Deal found 12/3$614
This Kiwi.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:49 amGYE - MYR
1 stop16h 59mMultiple Airlines
Mon 12/2210:40 amMYR - GYE
2 stops37h 13mMultiple Airlines
Deal found 12/2$629
This Mytrip deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:49 amGYE - MYR
1 stop16h 59mSpirit Airlines
Mon 12/229:54 amMYR - GYE
1 stop13h 59mSpirit Airlines
Deal found 12/2$641

Find flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated December 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$278
(Mytrip)

One-way from

$185
(CheapOair)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 5, 2025.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Wed 1/28

9:07 pm-12:21 am

3 stops27h 14m

$304

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sun 1/25

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Mon 2/9

6:00 am-12:21 am

1 stop18h 21m

$311

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

6:50 pm-8:18 am

1 stop13h 28m

Charlotte Douglas

Sat 1/31

6:00 am-12:21 am

1 stop18h 21m

$317

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 2/10

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Thu 2/19

11:12 am-12:01 am

2 stops12h 49m

$318

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 2/26

12:59 am-6:02 pm

1 stop17h 03m

Charlotte Douglas

Tue 3/10

1:24 pm-11:01 pm

1 stop10h 37m

$319

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 2/3

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Sun 2/15

7:00 am-12:01 am

1 stop17h 01m

$339

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sun 12/28

12:49 am-9:39 am

1 stop8h 50m

Charlotte Douglas

Tue 1/13

9:07 pm-12:21 am

3 stops27h 14m

$344

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Sun 1/18

1:26 am-5:36 pm

1 stop16h 10m

Charleston

Fri 1/30

6:35 pm-12:21 am

1 stop29h 46m

$344

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 1/13

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Thu 1/22

11:12 am-12:21 am

2 stops13h 09m

$363

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sat 12/27

12:49 am-8:39 pm

2 stops19h 50m

Charlotte Douglas

Mon 1/12

11:12 am-12:21 am

2 stops13h 09m

$365

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 32 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina

What is the cheapest month to book a flight from Guayaquil to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GYE to SC?

Find hourly flight availability from Guayaquil to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 5, 2025.

A simple way to save on the total cost of your ticket is to fly from Guayaquil to South Carolina in the evening. If you’re flexible enough to do this you can expect to save up to 64% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 15h 28m. Fly via Spirit Airlines or American Airlines to get the fastest option. The distance between Guayaquil and South Carolina is about 2582 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo - Charleston.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Guayaquil to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Guayaquil to South Carolina (average of $178). Flying from Guayaquil to South Carolina in June is currently the most expensive (average of $899). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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