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$205+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Mar 17 — Mar 241
Tue 3/17
Tue 3/24
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 15, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Sat 5/98:55 am
CLT
-
GYE
1 stop15h 06m
Spirit Airlines
Deal found 2/11$297
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:00 pm
GYE
-
CHS
1 stop18h 00m
Delta
Tue 11/34:30 pm
CHS
-
GYE
2 stops15h 25m
Delta
Deal found 2/13$307
This Cheapflightsfares deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2611:59 pm
GYE
-
CLT
1 stop13h 14m
Spirit Airlines
Wed 6/106:00 am
CLT
-
GYE
1 stop18h 01m
Spirit Airlines
Deal found 2/13$309
This Cheapflightsfares deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:59 pm
GYE
-
CLT
1 stop19h 18m
Spirit Airlines
Tue 3/241:20 pm
CLT
-
GYE
1 stop10h 44m
Spirit Airlines
Deal found 2/11$336
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:59 pm
GYE
-
CLT
1 stop13h 18m
Multiple Airlines
Tue 3/319:00 pm
CLT
-
GYE
1 stop27h 04m
Multiple Airlines
Deal found 2/11$337
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:50 pm
GYE
-
CLT
1 stop16h 17m
Multiple Airlines
Tue 3/247:00 am
CLT
-
GYE
2 stops27h 15m
Multiple Airlines
Deal found 2/11$338
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:50 pm
GYE
-
CLT
1 stop16h 17m
Multiple Airlines
Mon 3/309:47 pm
CLT
-
GYE
2 stops12h 08m
Multiple Airlines
Deal found 2/11$340
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:40 am
GYE
-
MYR
2 stops26h 33m
Multiple Airlines
Tue 3/176:28 pm
MYR
-
GYE
1 stop29h 36m
Multiple Airlines
Deal found 2/11$344
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:05 am
GYE
-
CLT
2 stops15h 12m
Multiple Airlines
Mon 4/137:00 am
CLT
-
GYE
1 stop23h 20m
Multiple Airlines
Deal found 2/14$345
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:59 pm
GYE
-
MYR
1 stop8h 42m
Spirit Airlines
Tue 5/197:51 pm
MYR
-
GYE
1 stop28h 13m
Spirit Airlines
Deal found 2/11$347
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:50 pm
GYE
-
CLT
1 stop16h 17m
Multiple Airlines
Tue 3/318:56 am
CLT
-
GYE
2 stops16h 49m
Multiple Airlines
Deal found 2/11$347
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:59 pm
GYE
-
MYR
1 stop8h 42m
Multiple Airlines
Tue 5/197:51 pm
MYR
-
GYE
2 stops28h 39m
Multiple Airlines
Deal found 2/11$352

Find flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated February 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Cheapflightsfares)

One-way from

$205
(Trip.com)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
Search Deals
From Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals
One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 15, 2026.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 4/22

11:59 pm-2:13 pm

1 stop13h 14m

Charlotte Douglas

Sat 5/9

6:00 am-11:01 pm

1 stop18h 01m

$297

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 3/24

11:59 pm-2:17 pm

1 stop13h 18m

Charlotte Douglas

Tue 3/31

9:00 pm-11:04 pm

1 stop27h 04m

$337

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Mon 3/16

6:50 pm-12:07 pm

1 stop16h 17m

Charlotte Douglas

Mon 3/30

9:47 pm-8:55 am

2 stops12h 08m

$340

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Tue 3/10

4:40 am-8:13 am

2 stops26h 33m

Myrtle Beach Intl

Tue 3/17

6:28 pm-11:04 pm

1 stop29h 36m

$344

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 4/8

4:05 am-8:17 pm

2 stops15h 12m

Charlotte Douglas

Mon 4/13

7:00 am-5:20 am

1 stop23h 20m

$345

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 4/15

11:59 pm-10:17 am

1 stop9h 18m

Charlotte Douglas

Wed 5/27

8:55 am-11:04 pm

1 stop15h 09m

$363

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 4/14

11:59 pm-2:13 pm

1 stop13h 14m

Charlotte Douglas

Sat 4/25

6:00 am-11:04 pm

1 stop18h 04m

$365

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Wed 3/11

6:55 pm-12:07 pm

2 stops16h 12m

Charlotte Douglas

Fri 3/20

9:00 pm-11:04 pm

1 stop27h 04m

$368

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 3/12

7:05 pm-10:12 am

1 stop14h 07m

Charlotte Douglas

Fri 3/20

8:56 am-11:04 pm

1 stop15h 08m

$368

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Fri 4/24

11:59 pm-9:41 am

1 stop8h 42m

Myrtle Beach Intl

Tue 5/26

7:51 pm-11:04 pm

1 stop28h 13m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 39 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 13h 14m. Fly via Spirit Airlines to get the fastest option. The distance between Guayaquil and South Carolina is about 2582 mi.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo - Charleston.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Guayaquil to South Carolina

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