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$160+ Cheap flights from Guayaquil (GYE) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/19. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — CHS
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Guayaquil to South Carolina

Cheapest flights from Guayaquil to South Carolina
Explore the most affordable flight options available from Guayaquil to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This OneTravel deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:49 amGYE - CLT
1 stop19h 44mSpirit Airlines
Wed 1/79:38 pmCLT - GYE
1 stop26h 43mSpirit Airlines
Deal found 12/28$637
This Kiwi.com deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:50 pmGYE - CLT
1 stop25h 19mMultiple Airlines
Fri 3/69:37 pmCLT - GYE
2 stops11h 38mMultiple Airlines
Deal found 12/29$673
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 pmGYE - CLT
1 stop25h 04mMultiple Airlines
Wed 1/79:38 pmCLT - GYE
1 stop26h 43mMultiple Airlines
Deal found 12/28$675
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2812:49 amGYE - CLT
1 stop19h 44mMultiple Airlines
Mon 1/52:57 pmCLT - GYE
2 stops29h 23mMultiple Airlines
Deal found 12/28$682
This OneTravel deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2912:49 amGYE - CLT
2 stops31h 11mSpirit Airlines
Wed 1/79:34 pmCLT - GYE
2 stops26h 47mSpirit Airlines
Deal found 12/28$855
This Mytrip deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:40 pmGYE - CLT
2 stops24h 16mMultiple Airlines
Wed 1/75:14 pmCLT - GYE
3 stops31h 07mMultiple Airlines
Deal found 12/28$879

Find flight deals from Guayaquil to South Carolina

Keep the following information in mind while searching for Guayaquil to South Carolina flight deals. Data was last updated December 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$268
(Cheapflightsfares)

One-way from

$160
(Cheapflightsfares)
Provider with most accurate pricing for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flight deals.
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Provider most trusted by Cheapflights users for Guayaquil Jose Joaquin de Olmedo-Myrtle Beach Intl flights.
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From Guayaquil Jose Joaquin de Olmedo to South Carolina
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One-way flight from Guayaquil Jose Joaquin de Olmedo to South Carolina
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Guayaquil to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Guayaquil to South Carolina that are best for you.

Fly from

Guayaquil

Fly to

South Carolina

Route

Depart

Return

Price

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Sun 3/1

12:59 am-5:40 pm

1 stop16h 41m

Charleston

Tue 5/12

7:00 am-11:01 pm

1 stop17h 01m

$268

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

1:26 am-10:55 am

1 stop9h 29m

Charlotte Douglas

Wed 1/28

6:00 am-12:21 am

1 stop18h 21m

$281

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Tue 3/3

3:30 pm-12:21 pm

2 stops20h 51m

Charleston

Tue 5/12

7:39 pm-1:31 pm

2 stops18h 52m

$324

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Thu 2/26

12:59 am-4:54 pm

2 stops15h 55m

Charlotte Douglas

Tue 3/10

5:55 am-11:04 pm

1 stop18h 09m

$332

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Fri 1/16

1:26 am-5:36 pm

1 stop16h 10m

Charleston

Sat 1/31

6:35 pm-12:21 am

1 stop29h 46m

$338

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Sat 1/17

4:30 pm-11:48 am

2 stops19h 18m

Charleston

Sat 1/31

5:18 pm-7:20 am

2 stops14h 02m

$340

GuayaquilCharleston

GYE - CHS

GYECHS

Guayaquil Jose Joaquin de Olmedo

Thu 2/19

12:59 am-5:40 pm

1 stop16h 41m

Charleston

Wed 2/25

5:00 pm-12:04 am

2 stops31h 04m

$354

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Sun 1/25

1:26 am-6:48 pm

1 stop17h 22m

Charlotte Douglas

Mon 2/9

11:12 am-12:21 am

2 stops13h 09m

$356

GuayaquilCharlotte

GYE - CLT

GYECLT

Guayaquil Jose Joaquin de Olmedo

Tue 1/13

1:26 am-4:54 pm

2 stops15h 28m

Charlotte Douglas

Thu 1/22

11:12 am-12:21 am

2 stops13h 09m

$376

GuayaquilMyrtle Beach

GYE - MYR

GYEMYR

Guayaquil Jose Joaquin de Olmedo

Sun 2/8

1:26 am-7:20 pm

1 stop17h 54m

Myrtle Beach Intl

Mon 5/4

7:51 pm-11:01 pm

1 stop28h 10m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 34 results
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Best time to book a flight from Guayaquil to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Guayaquil with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Guayaquil to South Carolina
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Guayaquil to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Guayaquil to South Carolina?

    Located just 2.5 mi from the city center, Guayaquil Jose Joaquin de Olmedo (GYE) is the airport most travelers will use when flying to South Carolina from Guayaquil.

  • How long is the flight from Guayaquil to South Carolina?

    There are many flights that can get you from Guayaquil to South Carolina in 16h 41m. Fly via Spirit Airlines, American Airlines, or Delta to get the fastest option. The distance between Guayaquil and South Carolina is about 2420 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Guayaquil to South Carolina?

    The most popular flight routes from Guayaquil to South Carolina are Guayaquil Jose Joaquin de Olmedo - Charlotte Douglas, Guayaquil Jose Joaquin de Olmedo - Myrtle Beach Intl and Guayaquil Jose Joaquin de Olmedo - Charleston.

  • Can I find deals for flights from Guayaquil to South Carolina that include hotel bookings?

    Yes. In addition to deals on Guayaquil to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Guayaquil to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Guayaquil to South Carolina.

  • Can I find deals for business class flights from Guayaquil to South Carolina?

    Yes. Cheapflights offers flight deals from Guayaquil to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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