Guayaquil

$197+ Cheap flights from South Carolina to Guayaquil (GYE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GYE
Jul 8 — Jul 151
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Guayaquil with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Guayaquil

Keep the following information in mind while searching for South Carolina to Guayaquil flight deals. Data was last updated July 3, 2025.

Round-trip from

$443
(Avianca Connect)

One-way from

$197
(Avianca Connect)
From South Carolina to Guayaquil Jose Joaquin de Olmedo
One-way flight from South Carolina to Guayaquil Jose Joaquin de Olmedo

Find flight deals from South Carolina to Guayaquil

Cheapest flights from South Carolina to Guayaquil
Explore the most affordable flight options available from South Carolina to Guayaquil. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Avianca Connect deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/66:00 amCLT - GYE
2 stops21h 05mMultiple Airlines
Wed 9/33:35 amGYE - CLT
2 stops16h 14mMultiple Airlines
Deal found 7/1$443
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2411:41 amCLT - GYE
2 stops27h 05mUnited Airlines
Tue 10/148:28 amGYE - CLT
2 stops35h 44mUnited Airlines
Deal found 7/3$517
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:19 amCLT - GYE
1 stop16h 41mAmerican Airlines
Mon 12/87:30 amGYE - CLT
1 stop13h 55mAmerican Airlines
Deal found 7/2$569
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:28 pmCHS - GYE
2 stops49h 20mAmerican Airlines
Tue 9/308:20 amGYE - CHS
2 stops24h 43mAmerican Airlines
Deal found 7/1$571
This LATAM Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:45 amCHS - GYE
2 stops15h 38mLATAM Airlines
Wed 10/153:20 pmGYE - CHS
2 stops16h 18mLATAM Airlines
Deal found 7/2$579
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:45 amCHS - GYE
2 stops20h 20mUnited Airlines
Fri 9/268:32 amGYE - CHS
2 stops30h 36mUnited Airlines
Deal found 7/3$595
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2312:50 pmCHS - GYE
2 stops50h 20mDelta
Tue 9/308:56 pmGYE - CHS
2 stops11h 20mDelta
Deal found 7/3$602
This United deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/116:30 amCHS - GYE
2 stops35h 26mMultiple Airlines
Sat 11/222:35 pmGYE - CHS
2 stops42h 21mMultiple Airlines
Deal found 7/3$647
This Mytrip deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/611:28 amMYR - GYE
3 stops27h 07mMultiple Airlines
Tue 7/86:30 pmGYE - MYR
2 stops25h 34mMultiple Airlines
Deal found 7/2$839
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/42:48 pmMYR - GYE
2 stops30h 00mAmerican Airlines
Wed 10/88:15 amGYE - MYR
2 stops25h 11mAmerican Airlines
Deal found 7/2$874
This JetBlue deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:10 pmCHS - GYE
1 stop10h 05mJetBlue
Sat 11/297:15 amGYE - CHS
1 stop10h 31mJetBlue
Deal found 7/3$925
This Copa Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1110:00 amCHS - GYE
2 stops13h 41mCopa Airlines
Fri 11/214:31 amGYE - CHS
2 stops14h 29mCopa Airlines
Deal found 7/3$1,607

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from South Carolina to Guayaquil that are best for you.

Fly from

South Carolina

Fly to

Guayaquil

Route

Depart

Return

Price

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 8/6

6:00 am-2:05 am

2 stops21h 05m

Guayaquil Jose Joaquin de Olmedo

Wed 9/3

3:35 am-8:49 pm

2 stops16h 14m

$443

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Wed 9/24

11:41 am-1:46 pm

2 stops27h 05m

Guayaquil Jose Joaquin de Olmedo

Tue 10/14

8:28 am-9:12 pm

2 stops35h 44m

$517

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 11/25

5:19 am-10:00 pm

1 stop16h 41m

Guayaquil Jose Joaquin de Olmedo

Mon 12/8

7:30 am-9:25 pm

1 stop13h 55m

$569

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/23

7:28 pm-7:48 pm

2 stops49h 20m

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

8:20 am-10:03 am

2 stops24h 43m

$571

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/16

6:45 am-2:05 am

2 stops20h 20m

Guayaquil Jose Joaquin de Olmedo

Fri 9/26

8:32 am-4:08 pm

2 stops30h 36m

$595

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Tue 9/23

12:50 pm-2:10 pm

2 stops50h 20m

Guayaquil Jose Joaquin de Olmedo

Tue 9/30

8:56 pm-9:16 am

2 stops11h 20m

$602

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Fri 8/15

9:40 pm-9:55 am

3 stops37h 15m

Guayaquil Jose Joaquin de Olmedo

Fri 8/22

4:15 am-7:12 pm

2 stops13h 57m

$667

Myrtle BeachGuayaquil

MYR - GYE

MYRGYE

Myrtle Beach Intl

Sat 10/4

2:48 pm-7:48 pm

2 stops30h 00m

Guayaquil Jose Joaquin de Olmedo

Wed 10/8

8:15 am-10:26 am

2 stops25h 11m

$874

CharlotteGuayaquil

CLT - GYE

CLTGYE

Charlotte Douglas

Tue 8/19

11:00 am-2:05 am

2 stops16h 05m

$197

CharlestonGuayaquil

CHS - GYE

CHSGYE

Charleston

Mon 7/14

9:38 am-11:17 am

2 stops26h 39m

$227

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Showing 1-10 of 14 results
1
2

Best time to book a flight from South Carolina to Guayaquil

Have a flexible travel schedule? Discover the best time to fly to Guayaquil from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Guayaquil

What is the cheapest time of day to fly from SC to GYE?

Find hourly flight availability from South Carolina to Guayaquil. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

When flying from South Carolina to Guayaquil, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from South Carolina to Guayaquil?

Reviews of airlines servicing Guayaquil

Get insights into the airlines that provide service to Guayaquil. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Guayaquil. Reviews last updated July 3, 2025.
Get a feel of what it's like to fly with United Airlines, American Airlines, and Avianca from South Carolina to Guayaquil by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.1

Food

6.6

Entertainment

7.0

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Crew

8.1

Food

6.6

Entertainment

7.0

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Crew

8.1

Food

6.6

Entertainment

7.0

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Crew

8.1

Food

6.6

Entertainment

7.0

Comfort

7.3

Boarding

7.7

Overall

7.4

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Guayaquil. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Guayaquil from South Carolina?

    Guayaquil Jose Joaquin de Olmedo (GYE), located 2.5 mi from the city center, is the airport you fly into when you book flights from South Carolina to Guayaquil.

  • What are the most popular routes from South Carolina to Guayaquil?

  • Can I find deals for flights from South Carolina to Guayaquil that include hotel bookings?

    Yes. In addition to deals on South Carolina to Guayaquil flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Guayaquil?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Guayaquil.

  • Can I find deals for business class flights from South Carolina to Guayaquil?

    Yes. Cheapflights offers flight deals from South Carolina to Guayaquil by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Guayaquil?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Guayaquil (average of $440). Flying from South Carolina to Guayaquil in December is currently the most expensive (average of $722). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Guayaquil

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from South Carolina to Guayaquil

Discover the top airline that operate flights from South Carolina to Guayaquil. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$451Average$775FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.