$43+ Cheap flights from O'Hare Intl (ORD) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Feb 20 — Feb 271
1 adult, Economy
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Cheapest flights from O'Hare Intl to South CarolinaExplore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:31 pm
ORD
- CLT
Nonstop2h 17m
Frontier
Mon 4/69:40 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Deal found 1/20![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/2310:58 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/19![Frontier logo]()
$74
This Frontier deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/54:19 pm
ORD
- CLT
Nonstop2h 06m
Frontier
Sun 2/88:49 pm
CLT
- ORD
Nonstop2h 22m
Frontier
Deal found 1/19![Frontier logo]()
$77
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/1610:42 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/19![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/64:19 pm
ORD
- CLT
Nonstop2h 06m
Frontier
Mon 2/98:20 pm
CLT
- ORD
Nonstop2h 22m
Frontier
Deal found 1/20![Frontier logo]()
$81
This Frontier deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/64:19 pm
ORD
- CLT
Nonstop2h 06m
Frontier
Sun 2/88:49 pm
CLT
- ORD
Nonstop2h 22m
Frontier
Deal found 1/18![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:01 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Sun 3/810:46 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/20![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Sun 3/810:46 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/19![Frontier logo]()
$86
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:11 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Sun 3/1510:42 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/20![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/126:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/2310:58 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/19![Frontier logo]()
$89
This Super.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/2310:58 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 1/19![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/175:58 pm
ORD
- MYR
1 stop19h 57m
Spirit Airlines
Tue 2/2410:09 am
MYR
- ORD
1 stop24h 13m
Spirit Airlines
Deal found 1/20![Spirit Airlines logo]()
$161
Find flight deals from O'Hare Intl to South Carolina
Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated January 21, 2026.
Most accurate provider | Justfly.com 3 stars |
|---|---|
Most trusted provider | Justfly.com 3 stars |
Round-trip from | $65 (Kiwi.com) |
One-way from | $43 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $360 |
Good round-trip deal | $209 or less |
Good one-way deal | $178 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.
Fly from
O'Hare Intl
Fly to
South Carolina
Route
Depart
Return
Price
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 2/18
2:19 pm-5:24 pm
Nonstop2h 05m
Charlotte Douglas
Wed 2/25
6:00 am-7:26 am
Nonstop2h 26m
$139
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Fri 2/27
2:19 pm-5:24 pm
Nonstop2h 05m
Charlotte Douglas
Wed 3/4
6:00 am-7:26 am
Nonstop2h 26m
$158
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Thu 2/26
7:10 am-10:26 am
Nonstop2h 16m
Charlotte Douglas
Sun 3/1
6:15 am-7:41 am
Nonstop2h 26m
$177
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 2/17
2:19 pm-5:24 pm
Nonstop2h 05m
Charlotte Douglas
Thu 2/19
10:30 am-11:59 am
Nonstop2h 29m
$188
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 3/28
1:55 pm-4:51 pm
Nonstop1h 56m
Greenville
Tue 3/31
6:30 am-7:54 am
Nonstop2h 24m
$202
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 3/27
7:36 pm-10:28 pm
Nonstop1h 52m
Greenville
Mon 3/30
8:17 pm-9:36 pm
Nonstop2h 19m
$209
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 2/19
7:05 am-10:01 am
Nonstop1h 56m
Greenville
Thu 2/26
10:40 am-12:00 pm
Nonstop2h 20m
$209
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 7/2
1:59 pm-4:55 pm
Nonstop1h 56m
Greenville
Sun 7/5
6:46 am-7:48 am
Nonstop2h 02m
$209
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 3/7
1:55 pm-4:51 pm
Nonstop1h 56m
Greenville
Sat 3/14
5:32 pm-7:00 pm
Nonstop2h 28m
$209
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 5/6
8:55 pm-11:58 pm
Nonstop2h 03m
Greenville
Sat 5/9
8:19 pm-9:39 pm
Nonstop2h 20m
$212
Showing 1-10 of 60 results
Best time to book a flight from O'Hare Intl to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina
What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $60). Flying from Chicago O'Hare Intl Airport to South Carolina in December is currently the most expensive (average of $202). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from ORD to SC?
Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 27% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.
What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on January 17, 2026.
Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina
Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2026.
The most flights from ORD to USSC are scheduled on a Monday (17 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated January 21, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Overall
8.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for O'Hare Intl to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Top 5 airlines flying from O'Hare Intl to South Carolina
Discover the top 5 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$51 | Average$178 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$148 | Average$285 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$390 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$202 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$210 | Average$277 | FlexibilityNo cancel fee | On-time63% |