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$44+ Cheap flights from O'Hare Intl (ORD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/31. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from O'Hare Intl to South Carolina

Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated July 29, 2025.

Round-trip from

$113
(Cheapflightsfares)

One-way from

$44
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$252

Good round-trip deal

$170 or less

Good one-way deal

$93 or less
From Chicago O'Hare Intl to South Carolina
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One-way flight from Chicago O'Hare Intl to South Carolina
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Highest demand for flights based on searches. 12% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to South Carolina.
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Price to beat on a one-way flight from Chicago O'Hare Intl to South Carolina.
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Find flight deals from O'Hare Intl to South Carolina

Cheapest flights from O'Hare Intl to South Carolina
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:12 amORD - MYR
Nonstop2h 01mSpirit Airlines
Sun 8/242:18 pmMYR - ORD
Nonstop2h 25mSpirit Airlines
Deal found 7/27$113
This Cheapflightsfares deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/242:00 pmORD - CLT
Nonstop2h 27mFrontier
Sun 8/319:04 pmCLT - ORD
Nonstop2h 31mFrontier
Deal found 7/27$133
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/68:37 amORD - CLT
Nonstop2h 05mAmerican Airlines
Sat 9/61:36 pmCLT - ORD
Nonstop2h 11mAmerican Airlines
Deal found 7/27$134
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:40 amORD - CLT
Nonstop2h 20mMultiple Airlines
Tue 9/95:45 amCLT - ORD
1 stop12h 06mMultiple Airlines
Deal found 7/27$137
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:10 amORD - CLT
Nonstop2h 16mUnited Airlines
Mon 9/16:40 amCLT - ORD
Nonstop2h 20mUnited Airlines
Deal found 7/28$143
This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1011:13 amORD - CLT
1 stop11h 23mSpirit Airlines
Wed 9/175:45 amCLT - ORD
1 stop12h 06mSpirit Airlines
Deal found 7/27$160
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/168:10 amORD - CAE
1 stop4h 14mAmerican Airlines
Tue 9/231:54 pmCAE - ORD
1 stop4h 29mAmerican Airlines
Deal found 7/27$179
This Booking.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1112:05 pmORD - CAE
1 stop5h 16mSpirit Airlines
Sat 9/2011:48 amCAE - ORD
1 stop6h 51mSpirit Airlines
Deal found 7/27$192
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/158:26 amORD - SAV
Nonstop2h 11mAmerican Airlines
Mon 8/1812:29 pmSAV - ORD
Nonstop2h 31mAmerican Airlines
Deal found 7/28$198
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:10 amORD - CHS
Nonstop2h 25mUnited Airlines
Fri 10/245:50 pmCHS - ORD
1 stop6h 40mUnited Airlines
Deal found 7/29$199
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:15 amORD - CHS
1 stop6h 42mDelta
Tue 9/304:44 pmCHS - ORD
1 stop6h 30mDelta
Deal found 7/29$201
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/148:46 pmORD - CHS
Nonstop2h 29mAmerican Airlines
Sat 10/186:00 amCHS - ORD
1 stop4h 29mAmerican Airlines
Deal found 7/27$203

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

O'Hare Intl

Fly to

South Carolina

Route

Depart

Return

Price

ChicagoMyrtle Beach

ORD - MYR

ORDMYR

Chicago O'Hare Intl

Thu 8/21

10:12 am-1:13 pm

Nonstop2h 01m

Myrtle Beach Intl

Sun 8/24

2:18 pm-3:43 pm

Nonstop2h 25m

$113

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sun 8/24

2:00 pm-5:27 pm

Nonstop2h 27m

Charlotte Douglas

Sun 8/31

9:04 pm-10:35 pm

Nonstop2h 31m

$133

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Sat 9/6

8:37 am-11:42 am

Nonstop2h 05m

Charlotte Douglas

Sat 9/6

1:36 pm-2:47 pm

Nonstop2h 11m

$134

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 9/25

7:40 am-11:00 am

Nonstop2h 20m

Charlotte Douglas

Tue 9/30

5:45 am-4:51 pm

1 stop12h 06m

$136

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Thu 8/28

7:10 am-10:26 am

Nonstop2h 16m

Charlotte Douglas

Mon 9/1

6:40 am-8:00 am

Nonstop2h 20m

$143

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

Wed 9/10

11:13 am-11:36 pm

1 stop11h 23m

Charlotte Douglas

Wed 9/17

5:45 am-4:51 pm

1 stop12h 06m

$160

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

Tue 9/16

8:10 am-1:24 pm

1 stop4h 14m

Columbia Metropolitan

Tue 9/23

1:54 pm-5:23 pm

1 stop4h 29m

$179

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

Thu 9/11

12:05 pm-6:21 pm

1 stop5h 16m

Columbia Metropolitan

Sat 9/20

11:48 am-5:39 pm

1 stop6h 51m

$192

ChicagoSavannah

ORD - SAV

ORDSAV

Chicago O'Hare Intl

Fri 8/15

8:26 am-11:37 am

Nonstop2h 11m

Savannah/Hilton Head

Mon 8/18

12:29 pm-2:00 pm

Nonstop2h 31m

$198

ChicagoCharleston

ORD - CHS

ORDCHS

Chicago O'Hare Intl

Mon 8/18

10:26 am-7:12 pm

1 stop7h 46m

Charleston

Fri 8/22

8:17 pm-10:31 am

1 stop15h 14m

$198

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Showing 1-10 of 60 results
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Best time to book a flight from O'Hare Intl to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $217). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SC?

Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Chicago O'Hare Intl Airport to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina

Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 29, 2025.

The most flights from ORD to USSC are scheduled on a Monday (17 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from Chicago O'Hare Intl Airport to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
JetBlue
7.3
Good
2,913 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $44. Users have also found prices from $72 and $78 on United Airlines and Frontier, respectively.

  • What are the most popular routes from Chicago O'Hare Intl Airport to South Carolina?

    The most popular route from Chicago O'Hare Intl Airport to South Carolina is Chicago O'Hare Intl - Charlotte Douglas. You may also consider Chicago O'Hare Intl - Charleston or Chicago O'Hare Intl - Savannah/Hilton Head.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to South Carolina?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to South Carolina are Republic Airways (98%), Alaska Airlines (90%) and American Airlines (87%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to South Carolina?

    Looking at all options, your cheapest flight can be booked for $90. While the most popular route (Chicago O'Hare Intl - Charlotte Douglas) can be booked for $137 on average our data indicates $268 when flying from Chicago O'Hare Intl Airport to South Carolina.

  • Can I find deals for flights from O'Hare Intl to South Carolina that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to South Carolina.

  • Can I find deals for business class flights from O'Hare Intl to South Carolina?

    Yes. Cheapflights offers flight deals from O'Hare Intl to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $217). Flying from Chicago O'Hare Intl Airport to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for O'Hare Intl to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from O'Hare Intl to South Carolina

Discover the top 5 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$57Average$180FlexibilityNo cancel feeOn-time65%
DeltaCheapest$149Average$339FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$166Average$410FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$188Average$362FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$216Average$381FlexibilityNo cancel feeOn-time63%

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