South Carolina

$58+ Cheap flights from O'Hare Intl (ORD) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
avr. 9 — avr. 161
We work with more than 300 partners to bring you better travel deals

Find cheap flights from O'Hare Intl to South Carolina with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from O'Hare Intl to South Carolina

Cheapest flights from O'Hare Intl to South Carolina
Explore the most affordable flight options available from O'Hare Intl to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mars 10, 2026.

This Expedia deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/76:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
lun. 4/139:40 pm
CLT
-
ORD
Nonstop2h 27m
Multiple Airlines
Deal found 3/7$104
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 5/75:16 pm
ORD
-
CLT
Nonstop2h 15m
Frontier
lun. 5/189:26 pm
CLT
-
ORD
Nonstop2h 27m
Frontier
Deal found 3/7$105
This Priceline deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/36:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
ven. 4/1010:43 pm
CLT
-
ORD
Nonstop2h 21m
Multiple Airlines
Deal found 3/5$106
This Super.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 4/51:02 pm
ORD
-
CLT
Nonstop2h 10m
Frontier
ven. 4/1010:43 pm
CLT
-
ORD
Nonstop2h 21m
Frontier
Deal found 3/8$107
This Frontier deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/36:31 pm
ORD
-
CLT
Nonstop2h 17m
Frontier
ven. 4/1010:43 pm
CLT
-
ORD
Nonstop2h 21m
Frontier
Deal found 3/10$108
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 5/912:53 pm
ORD
-
CLT
1 stop9h 51m
Multiple Airlines
ven. 5/159:26 pm
CLT
-
ORD
Nonstop2h 27m
Multiple Airlines
Deal found 3/9$110
This Mytrip deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 4/46:01 pm
ORD
-
CLT
1 stop4h 52m
Multiple Airlines
sam. 4/117:09 pm
CLT
-
ORD
Nonstop2h 30m
Multiple Airlines
Deal found 3/7$111
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 4/166:22 pm
ORD
-
CLT
Nonstop2h 17m
Frontier
lun. 4/205:17 pm
CLT
-
ORD
Nonstop2h 33m
Frontier
Deal found 3/9$112
This Frontier deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 4/21:02 pm
ORD
-
CLT
Nonstop2h 10m
Frontier
ven. 4/1010:43 pm
CLT
-
ORD
Nonstop2h 21m
Frontier
Deal found 3/10$113
This Super.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 4/3012:16 pm
ORD
-
CLT
Nonstop2h 08m
Frontier
lun. 5/44:40 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
Deal found 3/6$114
This Super.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 4/175:16 pm
ORD
-
CLT
Nonstop2h 15m
Frontier
lun. 4/205:17 pm
CLT
-
ORD
Nonstop2h 33m
Frontier
Deal found 3/9$115
This Frontier deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/112:37 pm
ORD
-
CLT
Nonstop2h 08m
Frontier
lun. 5/44:40 pm
CLT
-
ORD
Nonstop2h 34m
Frontier
Deal found 3/5$116

Find flight deals from O'Hare Intl to South Carolina

Keep the following information in mind while searching for O'Hare Intl to South Carolina flight deals. Data was last updated mars 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$104
(Expedia)

One-way from

$58
(Super.com)

Popular in

December

Cheapest in

August

Average price

$434

Good round-trip deal

$271 or less

Good one-way deal

$128 or less
Provider with most accurate pricing for Chicago (CHI)-Myrtle Beach Intl flight deals.
Provider most trusted by Cheapflights users for Chicago (CHI)-Myrtle Beach Intl flights.
From Chicago O'Hare Intl to South Carolina
One-way flight from Chicago O'Hare Intl to South Carolina
Highest demand for flights based on searches. 13% potential increase in price ($51 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in March 2026
Price to beat on a round-trip flight from Chicago O'Hare Intl to South Carolina.
Price to beat on a one-way flight from Chicago O'Hare Intl to South Carolina.

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 10, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

ven. 5/1

7:22 am-10:45 am

Nonstop2h 23m

Charlotte Douglas

sam. 5/2

5:28 pm-6:53 pm

Nonstop2h 25m

$180

ChicagoHilton Head Island

ORD - HHH

ORDHHH

Chicago O'Hare Intl

lun. 4/27

7:10 am-3:20 pm

1 stop7h 10m

Hilton Head Island

mer. 5/6

4:00 pm-10:15 pm

1 stop7h 15m

$197

ChicagoHilton Head Island

ORD - HHH

ORDHHH

Chicago O'Hare Intl

mar. 4/28

7:10 am-3:20 pm

1 stop7h 10m

Hilton Head Island

mer. 5/6

4:00 pm-10:15 pm

1 stop7h 15m

$197

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

jeu. 6/4

6:00 am-12:05 pm

1 stop5h 05m

Greenville

sam. 6/6

7:20 am-12:56 pm

1 stop6h 36m

$213

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

sam. 4/18

5:59 pm-11:56 pm

1 stop4h 57m

Greenville

lun. 4/20

7:59 pm-11:59 pm

1 stop5h 00m

$213

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

mer. 5/13

7:00 am-12:14 pm

1 stop4h 14m

Charlotte Douglas

mer. 5/20

6:05 am-10:27 am

1 stop5h 22m

$217

ChicagoCharlotte

ORD - CLT

ORDCLT

Chicago O'Hare Intl

jeu. 4/9

11:20 am-5:00 pm

1 stop4h 40m

Charlotte Douglas

lun. 4/13

6:05 pm-4:15 pm

1 stop23h 10m

$225

ChicagoGreenville

ORD - GSP

ORDGSP

Chicago O'Hare Intl

mer. 5/27

1:18 pm-7:04 pm

1 stop4h 46m

Greenville

dim. 5/31

6:00 am-7:20 am

Nonstop2h 20m

$239

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

jeu. 4/16

8:15 am-1:14 pm

1 stop3h 59m

Columbia Metropolitan

sam. 4/18

4:01 pm-8:16 pm

1 stop5h 15m

$249

ChicagoColumbia

ORD - CAE

ORDCAE

Chicago O'Hare Intl

dim. 5/10

7:07 am-3:07 pm

1 stop7h 00m

Columbia Metropolitan

lun. 5/18

3:54 pm-8:26 pm

1 stop5h 32m

$249

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/8

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from O'Hare Intl to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to South Carolina

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

Currently, July is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $60). Flying from Chicago O'Hare Intl Airport to South Carolina in February is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to SC?

Find hourly flight availability from O'Hare Intl to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mars 10, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 25% on flights from Chicago O'Hare Intl Airport to South Carolina by exploring options for tickets in the evening.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to South Carolina. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago O'Hare Intl Airport to South Carolina

Explore weekly flight availability from O'Hare Intl to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated mars 10, 2026.

The most flights from ORD to USSC are scheduled on a Monday (22 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated mars 10, 2026.
Get a feel of what it's like to fly with Delta,United Airlines, andAmerican Airlines from Chicago O'Hare Intl Airport to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Food

7.2

Crew

8.5

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Chicago O'Hare Intl Airport to South Carolina?

    There are many flights that can get you from Chicago O'Hare Intl Airport to South Carolina in 2h 23m. Fly via United Airlines, Delta, or Contour to get the fastest option. Chicago O'Hare Intl Airport and South Carolina are separated by a distance of 599 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Chicago O'Hare Intl Airport to South Carolina one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $33. Users have also found prices from $99 and $108 on American Airlines and Southwest, respectively.

  • What are the most popular routes from Chicago O'Hare Intl Airport to South Carolina?

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to South Carolina?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to South Carolina are SkyWest Airlines (100%), PSA Airlines (100%) and Republic Airways (84%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to South Carolina?

    Looking at all options, your cheapest flight can be booked for $142. While the most popular route (Chicago O'Hare Intl - Savannah/Hilton Head) can be booked for $208 on average, our data indicates $313 when flying from Chicago O'Hare Intl Airport to South Carolina.

  • Can I find deals for flights from O'Hare Intl to South Carolina that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to South Carolina.

  • Can I find deals for business class flights from O'Hare Intl to South Carolina?

    Yes. Cheapflights offers flight deals from O'Hare Intl to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to South Carolina?

    Currently, July is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to South Carolina (average of $60). Flying from Chicago O'Hare Intl Airport to South Carolina in February is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for O'Hare Intl to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from O'Hare Intl to South Carolina

Discover the top 4 airlines that operate flights from O'Hare Intl to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mars 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$51Average$166FlexibilityNo cancel feeOn-time65%
DeltaCheapest$146Average$258FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$153Average$374FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$202Average$361FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.