$133+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
juin 18 — juin 251
Round-trip
1 adult, Economy
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mai 19, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mai 19, 2026.
This KAYAK deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/227:00 am
JAX
- MDE
1 stop15h 10m
Azul
lun. 10/269:45 am
MDE
- JAX
1 stop12h 20m
Azul
Deal found 5/17![Azul logo]()
$316
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/247:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
jeu. 8/279:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/16![United Airlines logo]()
$317
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 8/236:12 am
JAX
- MDE
2 stops39h 58m
United Airlines
jeu. 8/279:45 am
MDE
- JAX
2 stops24h 00m
United Airlines
Deal found 5/17![United Airlines logo]()
$335
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/227:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
lun. 10/269:45 am
MDE
- JAX
3 stops33h 01m
United Airlines
Deal found 5/17![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/87:18 am
JAX
- CTG
1 stop7h 56m
American Airlines
lun. 11/164:15 pm
CTG
- JAX
2 stops19h 27m
American Airlines
Deal found 5/17![American Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/111:50 am
JAX
- MDE
1 stop10h 15m
United Airlines
dim. 12/131:15 am
MDE
- JAX
1 stop16h 22m
United Airlines
Deal found 5/17![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/16:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
jeu. 6/49:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/18![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/226:05 pm
JAX
- CTG
2 stops19h 30m
American Airlines
jeu. 6/253:13 pm
CTG
- JAX
1 stop7h 46m
American Airlines
Deal found 5/18![American Airlines logo]()
$394
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/216:28 pm
JAX
- CTG
1 stop19h 07m
American Airlines
sam. 7/41:35 pm
CTG
- JAX
1 stop9h 40m
American Airlines
Deal found 5/19![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/74:35 pm
JAX
- CTG
2 stops21h 00m
American Airlines
sam. 8/151:35 pm
CTG
- JAX
1 stop9h 34m
American Airlines
Deal found 5/18![American Airlines logo]()
$460
This Justfly.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/73:18 pm
JAX
- CTG
1 stop21h 17m
JetBlue
sam. 8/1512:35 pm
CTG
- JAX
1 stop6h 20m
JetBlue
Deal found 5/18![JetBlue logo]()
$461
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 6/266:28 pm
JAX
- CTG
1 stop19h 07m
American Airlines
jeu. 7/21:35 pm
CTG
- JAX
1 stop18h 52m
American Airlines
Deal found 5/16![American Airlines logo]()
$465
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mai 19, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mai 19, 2026.
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/247:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
jeu. 8/279:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/16![United Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/226:05 pm
JAX
- CTG
2 stops19h 30m
American Airlines
jeu. 6/253:13 pm
CTG
- JAX
1 stop7h 46m
American Airlines
Deal found 5/18![American Airlines logo]()
$394
This Justfly.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/227:12 am
JAX
- CTG
1 stop5h 23m
JetBlue
mer. 7/2912:35 pm
CTG
- JAX
1 stop6h 20m
JetBlue
Deal found 5/15![JetBlue logo]()
$475
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 7/45:30 am
JAX
- CTG
1 stop8h 45m
Delta
jeu. 7/92:30 pm
CTG
- JAX
1 stop7h 32m
Delta
Deal found 5/18![Delta logo]()
$485
This Avianca deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/15:35 pm
JAX
- BOG
1 stop13h 40m
Multiple Airlines
lun. 9/79:05 am
BOG
- JAX
1 stop9h 50m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$559
This KAYAK deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 9/138:10 pm
JAX
- BOG
2 stops25h 00m
LATAM Airlines
dim. 9/208:40 am
BOG
- JAX
2 stops24h 41m
LATAM Airlines
Deal found 5/16![LATAM Airlines logo]()
$565
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 8/236:12 am
JAX
- MDE
2 stops39h 58m
United Airlines
jeu. 8/279:45 am
MDE
- JAX
2 stops24h 00m
United Airlines
Deal found 5/18![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/16:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
jeu. 6/49:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/18![United Airlines logo]()
$387
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/216:05 pm
JAX
- CTG
2 stops19h 30m
American Airlines
sam. 7/41:35 pm
CTG
- JAX
2 stops20h 17m
American Airlines
Deal found 5/17![American Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 10/224:58 pm
JAX
- MDE
2 stops29h 12m
United Airlines
lun. 10/269:45 am
MDE
- JAX
3 stops33h 01m
United Airlines
Deal found 5/17![United Airlines logo]()
$389
This JetBlue deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/227:12 am
JAX
- CTG
1 stop5h 23m
JetBlue
jeu. 7/2312:35 pm
CTG
- JAX
1 stop6h 20m
JetBlue
Deal found 5/17![JetBlue logo]()
$485
This BusinessClass deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 10/187:19 pm
JAX
- SDU
2 stops14h 31m
GOL
dim. 10/256:00 am
SDU
- JAX
2 stops16h 00m
GOL
Deal found 5/19![GOL logo]()
$1,034
This American Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/87:18 am
JAX
- CTG
1 stop6h 15m
American Airlines
lun. 11/162:34 pm
CTG
- JAX
1 stop9h 25m
American Airlines
Deal found 5/17![American Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 9/138:10 pm
JAX
- BOG
1 stop18h 30m
Delta
dim. 9/202:55 pm
BOG
- JAX
1 stop8h 09m
Delta
Deal found 5/16![Delta logo]()
$566
This Justfly.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/227:12 am
JAX
- CTG
1 stop5h 23m
JetBlue
mar. 7/2812:35 pm
CTG
- JAX
1 stop24h 43m
JetBlue
Deal found 5/15![JetBlue logo]()
$563
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 6/67:57 pm
JAX
- CTG
2 stops19h 16m
American Airlines
mar. 6/93:13 pm
CTG
- JAX
2 stops20h 40m
American Airlines
Deal found 5/19![American Airlines logo]()
$519
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 7/168:18 pm
JAX
- BOG
2 stops22h 32m
Delta
sam. 8/89:00 am
BOG
- JAX
1 stop7h 45m
Delta
Deal found 5/17![Delta logo]()
$575
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
dim. 6/219:45 am
MDE
- JAX
2 stops35h 14m
United Airlines
Deal found 5/17![United Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/16:30 am
JAX
- BOG
2 stops12h 20m
Delta
lun. 9/711:00 am
BOG
- JAX
2 stops22h 21m
Delta
Deal found 5/14![Delta logo]()
$579
This Mytrip deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/1410:20 am
JAX
- SDU
2 stops29h 25m
Air Canada
lun. 6/221:50 pm
SDU
- JAX
3 stops32h 41m
Air Canada
Deal found 5/19![Air Canada logo]()
$1,447
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 6/116:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
mar. 6/169:45 am
MDE
- JAX
2 stops24h 05m
United Airlines
Deal found 5/19![United Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 7/178:18 pm
JAX
- BOG
2 stops22h 32m
Delta
lun. 7/2011:00 am
BOG
- JAX
2 stops12h 10m
Delta
Deal found 5/17![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 6/109:20 am
JAX
- MDE
2 stops36h 50m
United Airlines
dim. 6/149:45 am
MDE
- JAX
2 stops23h 55m
United Airlines
Deal found 5/15![United Airlines logo]()
$510
This LATAM Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/227:30 am
JAX
- SCL
2 stops21h 05m
LATAM Airlines
mer. 9/3011:00 pm
SCL
- JAX
2 stops20h 58m
LATAM Airlines
Deal found 5/14![LATAM Airlines logo]()
$871
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/23:45 pm
JAX
- UIO
2 stops13h 13m
Delta
ven. 11/137:00 pm
UIO
- JAX
2 stops19h 47m
Delta
Deal found 5/18![Delta logo]()
$619
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 9/137:17 pm
JAX
- LIM
1 stop20h 28m
American Airlines
lun. 9/2811:45 pm
LIM
- JAX
1 stop18h 06m
American Airlines
Deal found 5/19![American Airlines logo]()
$695
This United Airlines deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 7/207:09 pm
JAX
- BOG
1 stop10h 16m
United Airlines
mar. 7/287:20 am
BOG
- JAX
2 stops26h 30m
United Airlines
Deal found 5/14![United Airlines logo]()
$555
This Delta deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 11/55:30 am
JAX
- LIM
2 stops16h 05m
Delta
lun. 11/912:00 pm
LIM
- JAX
1 stop12h 02m
Delta
Deal found 5/16![Delta logo]()
$687
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 9/136:30 am
JAX
- BOG
2 stops23h 24m
United Airlines
dim. 9/208:30 am
BOG
- JAX
3 stops35h 24m
United Airlines
Deal found 5/16![United Airlines logo]()
$575
This BusinessClass deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/16:43 pm
JAX
- SDU
2 stops23h 57m
GOL
mer. 7/86:05 am
SDU
- JAX
2 stops19h 10m
GOL
Deal found 5/18![GOL logo]()
$1,150
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated mai 19, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated mai 19, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/1911:32 am
JAX
- UIO
2 stops31h 33m
Multiple Airlines
jeu. 5/215:25 pm
UIO
- JAX
1 stop28h 55m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/16:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
jeu. 6/49:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/18![United Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 6/311:28 am
JAX
- MDE
2 stops21h 47m
Multiple Airlines
mar. 6/911:30 am
MDE
- JAX
1 stop21h 55m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 6/67:57 pm
JAX
- CTG
2 stops19h 16m
American Airlines
mar. 6/93:13 pm
CTG
- JAX
2 stops20h 40m
American Airlines
Deal found 5/19![American Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 6/109:20 am
JAX
- MDE
2 stops36h 50m
United Airlines
dim. 6/149:45 am
MDE
- JAX
1 stop12h 35m
United Airlines
Deal found 5/15![United Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 6/116:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
mar. 6/169:45 am
MDE
- JAX
2 stops24h 05m
United Airlines
Deal found 5/19![United Airlines logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 6/116:28 pm
JAX
- MDE
2 stops38h 47m
Multiple Airlines
mar. 6/1611:30 am
MDE
- JAX
1 stop21h 55m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
dim. 6/219:45 am
MDE
- JAX
2 stops35h 14m
United Airlines
Deal found 5/17![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/216:28 pm
JAX
- CTG
1 stop19h 07m
American Airlines
sam. 7/41:35 pm
CTG
- JAX
1 stop9h 40m
American Airlines
Deal found 5/19![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/226:05 pm
JAX
- CTG
2 stops19h 30m
American Airlines
jeu. 6/253:13 pm
CTG
- JAX
1 stop7h 46m
American Airlines
Deal found 5/18![American Airlines logo]()
$394
This Delta deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 6/255:30 am
JAX
- BOG
2 stops13h 20m
Delta
lun. 6/2911:00 am
BOG
- JAX
2 stops11h 59m
Delta
Deal found 5/17![Delta logo]()
$591
This American Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 6/266:28 pm
JAX
- CTG
1 stop19h 07m
American Airlines
jeu. 7/21:35 pm
CTG
- JAX
1 stop18h 52m
American Airlines
Deal found 5/16![American Airlines logo]()
$465
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated mai 19, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated mai 19, 2026.
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/17:18 am
JAX
- MDE
1 stop16h 21m
American Airlines
Deal found 5/18![American Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/2611:28 am
JAX
- BOG
3 stops29h 32m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$192
This Avianca deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/12:17 pm
JAX
- UIO
1 stop17h 18m
Multiple Airlines
Deal found 5/17![Multiple Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 6/186:42 pm
JAX
- MDE
2 stops27h 28m
United Airlines
Deal found 5/19![United Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 11/17:49 am
JAX
- MDE
2 stops38h 16m
United Airlines
Deal found 5/18![United Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 7/186:28 pm
JAX
- BOG
3 stops57h 32m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/2711:28 am
JAX
- MDE
2 stops21h 47m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$208
This Avianca deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 5/305:34 pm
JAX
- UIO
1 stop14h 01m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$212
This KAYAK deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/276:00 am
JAX
- MDE
1 stop18h 50m
GOL
Deal found 5/14![GOL logo]()
$224
This FlightHub deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dim. 6/76:10 am
JAX
- UIO
1 stop25h 25m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$230
This Orbitz deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 5/295:34 pm
JAX
- UIO
2 stops44h 31m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$235
This Justfly.com deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 5/272:17 pm
JAX
- UIO
1 stop17h 18m
Multiple Airlines
Deal found 5/18![Multiple Airlines logo]()
$236
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated mai 19, 2026.
Round-trip from | $316 (KAYAK) |
|---|---|
One-way from | $133 (American Airlines) |
Popular in | July |
Cheapest in | April |
Average price | $600 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 19, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
lun. 8/24
7:05 am-9:10 pm
1 stop15h 05m
Medellín Jose Maria Cordova Intl
jeu. 8/27
9:45 am-11:20 pm
1 stop12h 35m
$317
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
dim. 8/23
6:12 am-9:10 pm
2 stops39h 58m
Medellín Jose Maria Cordova Intl
jeu. 8/27
9:45 am-10:45 am
2 stops24h 00m
$375
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
lun. 6/1
6:42 pm-9:10 pm
2 stops27h 28m
Medellín Jose Maria Cordova Intl
jeu. 6/4
9:45 am-11:20 pm
1 stop12h 35m
$387
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
jeu. 10/22
4:58 pm-9:10 pm
2 stops29h 12m
Medellín Jose Maria Cordova Intl
lun. 10/26
9:45 am-7:46 pm
3 stops33h 01m
$389
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
lun. 6/22
6:05 pm-12:35 pm
2 stops19h 30m
Cartagena Rafael Nunez
jeu. 6/25
3:13 pm-11:59 pm
1 stop7h 46m
$394
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
dim. 6/21
6:05 pm-12:35 pm
2 stops19h 30m
Cartagena Rafael Nunez
sam. 7/4
1:35 pm-10:52 am
2 stops20h 17m
$442
Quickest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
mer. 7/22
7:12 am-11:35 am
1 stop5h 23m
Cartagena Rafael Nunez
mer. 7/29
12:35 pm-7:55 pm
1 stop6h 20m
$475
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
dim. 6/14
7:05 am-9:10 pm
1 stop15h 05m
Medellín Jose Maria Cordova Intl
dim. 6/21
9:45 am-9:59 pm
2 stops35h 14m
$484
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
sam. 7/4
5:30 am-1:15 pm
1 stop8h 45m
Cartagena Rafael Nunez
jeu. 7/9
2:30 pm-11:02 pm
1 stop7h 32m
$485
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
mer. 7/22
7:12 am-11:35 am
1 stop5h 23m
Cartagena Rafael Nunez
jeu. 7/23
12:35 pm-7:55 pm
1 stop6h 20m
$485
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-MDE
JAX-CTG
JAX-UIO
JAX-BOG
JAX-SDU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-MDE
JAX-CTG
JAX-UIO
JAX-BOG
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $154). Flying from Jacksonville to South America in September is currently the most expensive (average of $507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Jacksonville to South America?
To ensure you get the cheapest price possible for a flight from Jacksonville to South America, you should look to book at least 71 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated mai 19, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Entertainment
7.8
Boarding
8.1
Comfort
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on mai 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 4 airlines flying from Jacksonville to South America
Discover the top 4 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mai 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$407 | Average$847 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$408 | Average$828 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$714 | FlexibilityNo cancel fee | On-time81% |