$150+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
May 3 — May 101
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to South America
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2026.
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 am
JAX
- CTG
1 stop9h 10m
Delta
Tue 5/122:13 pm
CTG
- JAX
1 stop7h 13m
Delta
Deal found 3/31![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:00 am
JAX
- CTG
1 stop9h 04m
American Airlines
Tue 5/121:25 pm
CTG
- JAX
2 stops22h 14m
American Airlines
Deal found 3/31![American Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:39 pm
JAX
- CTG
1 stop20h 41m
Delta
Sat 5/22:35 pm
CTG
- JAX
1 stop7h 15m
Delta
Deal found 4/2![Delta logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:00 am
JAX
- CTG
1 stop28h 04m
American Airlines
Mon 5/111:25 pm
CTG
- JAX
1 stop9h 34m
American Airlines
Deal found 3/29![American Airlines logo]()
$360
This BusinessClass deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:30 am
JAX
- CTG
2 stops17h 05m
LATAM Airlines
Sat 5/25:30 am
CTG
- JAX
2 stops11h 23m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:19 pm
JAX
- CTG
2 stops18h 45m
American Airlines
Sun 5/103:10 pm
CTG
- JAX
1 stop18h 00m
American Airlines
Deal found 4/2![American Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:00 am
JAX
- CTG
1 stop26h 09m
American Airlines
Fri 5/223:15 pm
CTG
- JAX
1 stop18h 53m
American Airlines
Deal found 3/31![American Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:50 am
JAX
- MDE
1 stop10h 15m
United Airlines
Wed 11/410:45 am
MDE
- JAX
1 stop12h 20m
United Airlines
Deal found 3/30![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:57 pm
JAX
- CTG
2 stops19h 16m
American Airlines
Wed 5/271:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 3/29![American Airlines logo]()
$368
This BusinessClass deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:30 am
JAX
- CTG
2 stops16h 00m
LATAM Airlines
Wed 7/155:30 am
CTG
- JAX
2 stops26h 07m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:25 pm
JAX
- MDE
1 stop28h 45m
United Airlines
Fri 5/89:45 am
MDE
- JAX
1 stop9h 17m
United Airlines
Deal found 4/1![United Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:06 am
JAX
- MDE
2 stops14h 09m
American Airlines
Wed 5/66:00 am
MDE
- JAX
1 stop16h 59m
American Airlines
Deal found 3/30![American Airlines logo]()
$377
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 3, 2026.
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:05 am
JAX
- CTG
1 stop7h 10m
Delta
Tue 5/122:13 pm
CTG
- JAX
1 stop9h 09m
Delta
Deal found 3/29![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:19 pm
JAX
- CTG
2 stops18h 45m
American Airlines
Sun 5/103:10 pm
CTG
- JAX
2 stops20h 29m
American Airlines
Deal found 3/29![American Airlines logo]()
$358
This BusinessClass deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:59 pm
JAX
- CTG
1 stop18h 21m
LATAM Airlines
Sat 5/24:25 am
CTG
- JAX
2 stops12h 28m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:35 am
JAX
- MDE
1 stop15h 35m
United Airlines
Wed 5/69:45 am
MDE
- JAX
1 stop9h 17m
United Airlines
Deal found 4/2![United Airlines logo]()
$367
This Orbitz deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:17 pm
JAX
- BAQ
2 stops27h 48m
Multiple Airlines
Mon 4/1310:10 pm
BAQ
- JAX
2 stops35h 34m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$702
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:12 pm
JAX
- CTG
2 stops18h 57m
American Airlines
Mon 5/111:25 pm
CTG
- JAX
2 stops20h 06m
American Airlines
Deal found 3/29![American Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:39 pm
JAX
- CTG
1 stop20h 41m
Delta
Sat 5/22:35 pm
CTG
- JAX
1 stop7h 15m
Delta
Deal found 4/2![Delta logo]()
$359
This BusinessClass deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:05 am
JAX
- CTG
2 stops14h 30m
LATAM Airlines
Sun 5/319:25 am
CTG
- JAX
2 stops31h 34m
LATAM Airlines
Deal found 3/29![LATAM Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:25 am
JAX
- MDE
2 stops12h 45m
United Airlines
Wed 9/309:45 am
MDE
- JAX
1 stop12h 20m
United Airlines
Deal found 4/2![United Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:12 pm
JAX
- CTG
2 stops18h 57m
American Airlines
Fri 5/13:10 pm
CTG
- JAX
2 stops20h 29m
American Airlines
Deal found 4/1![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:25 am
JAX
- MDE
2 stops12h 45m
United Airlines
Wed 10/79:45 am
MDE
- JAX
1 stop12h 20m
United Airlines
Deal found 3/31![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:20 am
JAX
- MDE
2 stops38h 50m
United Airlines
Tue 6/309:45 am
MDE
- JAX
2 stops23h 34m
United Airlines
Deal found 3/29![United Airlines logo]()
$386
This United Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:03 pm
JAX
- MDE
2 stops27h 07m
United Airlines
Tue 5/59:45 am
MDE
- JAX
2 stops28h 40m
United Airlines
Deal found 3/29![United Airlines logo]()
$386
This BusinessClass deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:10 pm
JAX
- CTG
2 stops24h 25m
LATAM Airlines
Sun 8/165:30 am
CTG
- JAX
2 stops14h 14m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$494
This KAYAK deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:35 am
JAX
- GRU
2 stops16h 55m
Copa Airlines
Sat 5/911:10 am
GRU
- JAX
2 stops24h 16m
Copa Airlines
Deal found 4/2![Copa Airlines logo]()
$1,098
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:35 am
JAX
- MDE
1 stop15h 35m
United Airlines
Wed 5/69:45 am
MDE
- JAX
1 stop9h 17m
United Airlines
Deal found 3/30![United Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:05 am
JAX
- BOG
2 stops12h 45m
Delta
Mon 6/811:00 am
BOG
- JAX
2 stops22h 45m
Delta
Deal found 4/1![Delta logo]()
$535
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
JAX
- BAQ
1 stop9h 38m
American Airlines
Sun 5/313:38 pm
BAQ
- JAX
2 stops20h 16m
American Airlines
Deal found 3/31![American Airlines logo]()
$534
This BusinessClass deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:05 am
JAX
- BAQ
2 stops19h 10m
LATAM Airlines
Mon 5/184:35 am
BAQ
- JAX
2 stops18h 48m
LATAM Airlines
Deal found 3/30![LATAM Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:05 am
JAX
- BOG
2 stops13h 45m
Delta
Fri 7/32:55 pm
BOG
- JAX
1 stop8h 04m
Delta
Deal found 3/29![Delta logo]()
$555
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:55 am
JAX
- BOG
1 stop14h 22m
American Airlines
Tue 5/196:30 am
BOG
- JAX
1 stop13h 45m
American Airlines
Deal found 3/30![American Airlines logo]()
$548
This LATAM Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
JAX
- BOG
2 stops11h 45m
LATAM Airlines
Tue 5/198:40 am
BOG
- JAX
2 stops12h 46m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$571
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2410:47 am
JAX
- BOG
1 stop9h 28m
Delta
Fri 5/2911:00 am
BOG
- JAX
2 stops12h 23m
Delta
Deal found 3/30![Delta logo]()
$579
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:19 pm
JAX
- BAQ
2 stops19h 06m
American Airlines
Mon 5/111:40 pm
BAQ
- JAX
1 stop9h 19m
American Airlines
Deal found 3/29![American Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:20 am
JAX
- BOG
2 stops13h 40m
United Airlines
Mon 6/88:30 am
BOG
- JAX
1 stop13h 50m
United Airlines
Deal found 3/31![United Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2811:46 am
JAX
- BOG
2 stops10h 31m
American Airlines
Tue 5/52:10 pm
BOG
- JAX
1 stop8h 49m
American Airlines
Deal found 3/29![American Airlines logo]()
$571
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:30 am
JAX
- LIM
2 stops16h 05m
Delta
Wed 9/912:05 am
LIM
- JAX
1 stop13h 45m
Delta
Deal found 3/30![Delta logo]()
$637
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:25 pm
JAX
- BOG
1 stop12h 29m
United Airlines
Sun 5/248:30 am
BOG
- JAX
1 stop10h 36m
United Airlines
Deal found 4/2![United Airlines logo]()
$568
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:12 pm
JAX
- BAQ
2 stops19h 18m
American Airlines
Mon 7/63:38 pm
BAQ
- JAX
2 stops20h 13m
American Airlines
Deal found 3/30![American Airlines logo]()
$588
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2110:44 am
JAX
- BAQ
2 stops15h 01m
Delta
Thu 7/94:35 am
BAQ
- JAX
2 stops18h 35m
Delta
Deal found 4/1![Delta logo]()
$660
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated April 3, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated April 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
JAX
- MDE
1 stop15h 15m
American Airlines
Wed 5/66:00 am
MDE
- JAX
2 stops17h 21m
American Airlines
Deal found 4/2![American Airlines logo]()
$382
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:39 pm
JAX
- CTG
1 stop20h 41m
Delta
Sat 5/22:35 pm
CTG
- JAX
1 stop7h 15m
Delta
Deal found 4/2![Delta logo]()
$359
This BusinessClass deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:30 am
JAX
- CTG
2 stops17h 05m
LATAM Airlines
Sat 5/25:30 am
CTG
- JAX
2 stops11h 23m
LATAM Airlines
Deal found 4/2![LATAM Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:06 am
JAX
- MDE
2 stops14h 09m
American Airlines
Wed 5/66:00 am
MDE
- JAX
1 stop16h 59m
American Airlines
Deal found 3/30![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:03 pm
JAX
- MDE
2 stops27h 07m
United Airlines
Fri 5/89:45 am
MDE
- JAX
2 stops23h 41m
United Airlines
Deal found 4/1![United Airlines logo]()
$372
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:35 am
JAX
- MDE
1 stop15h 35m
United Airlines
Wed 5/69:45 am
MDE
- JAX
1 stop9h 17m
United Airlines
Deal found 4/2![United Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:19 pm
JAX
- CTG
2 stops18h 45m
American Airlines
Sun 5/103:10 pm
CTG
- JAX
1 stop18h 00m
American Airlines
Deal found 4/2![American Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/811:00 am
JAX
- CTG
1 stop28h 04m
American Airlines
Mon 5/111:25 pm
CTG
- JAX
1 stop9h 34m
American Airlines
Deal found 3/29![American Airlines logo]()
$360
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 am
JAX
- CTG
1 stop9h 10m
Delta
Tue 5/122:13 pm
CTG
- JAX
1 stop7h 13m
Delta
Deal found 3/31![Delta logo]()
$353
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
- CTG
2 stops18h 45m
American Airlines
Tue 5/121:25 pm
CTG
- JAX
2 stops22h 14m
American Airlines
Deal found 3/31![American Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:00 am
JAX
- CTG
1 stop26h 09m
American Airlines
Fri 5/223:15 pm
CTG
- JAX
1 stop18h 53m
American Airlines
Deal found 3/31![American Airlines logo]()
$367
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:57 pm
JAX
- CTG
2 stops19h 16m
American Airlines
Wed 5/271:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 3/29![American Airlines logo]()
$368
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated April 3, 2026.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:00 am
JAX
- CTG
1 stop9h 04m
American Airlines
Deal found 4/1![American Airlines logo]()
$150
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:12 pm
JAX
- CTG
2 stops18h 57m
American Airlines
Deal found 3/31![American Airlines logo]()
$156
This KAYAK deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:30 am
JAX
- CTG
1 stop7h 45m
LATAM Airlines
Deal found 4/1![LATAM Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:39 pm
JAX
- BOG
3 stops45h 16m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:49 pm
JAX
- CTG
3 stops39h 37m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:39 pm
JAX
- BOG
2 stops46h 32m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:51 pm
JAX
- BOG
1 stop23h 24m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$226
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:33 pm
JAX
- MDE
1 stop23h 52m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:14 pm
JAX
- MDE
1 stop24h 11m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$239
This KAYAK deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/219:26 am
JAX
- MDE
2 stops35h 49m
GOL
Deal found 4/2![GOL logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 pm
JAX
- MDE
2 stops19h 13m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:37 am
JAX
- BOG
3 stops49h 18m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$249
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated April 3, 2026.
Round-trip from | $353 (Delta) |
|---|---|
One-way from | $150 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $771 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 5/9
7:05 am-1:15 pm
1 stop7h 10m
Cartagena Rafael Nunez
Tue 5/12
2:13 pm-12:22 am
1 stop9h 09m
$353
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Thu 5/7
8:19 pm-2:04 pm
2 stops18h 45m
Cartagena Rafael Nunez
Sun 5/10
3:10 pm-12:39 pm
2 stops20h 29m
$358
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Fri 5/8
6:12 pm-12:09 pm
2 stops18h 57m
Cartagena Rafael Nunez
Mon 5/11
1:25 pm-10:31 am
2 stops20h 06m
$358
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Thu 4/23
6:12 pm-12:09 pm
2 stops18h 57m
Cartagena Rafael Nunez
Fri 5/1
3:10 pm-12:39 pm
2 stops20h 29m
$358
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Fri 4/24
5:39 pm-1:20 pm
1 stop20h 41m
Cartagena Rafael Nunez
Sat 5/2
2:35 pm-10:50 pm
1 stop7h 15m
$359
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Fri 4/24
7:59 pm-1:20 pm
1 stop18h 21m
Cartagena Rafael Nunez
Sat 5/2
4:25 am-5:53 pm
2 stops12h 28m
$364
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Wed 5/27
7:05 am-8:35 pm
2 stops14h 30m
Cartagena Rafael Nunez
Sun 5/31
9:25 am-5:59 pm
2 stops31h 34m
$364
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Sun 5/3
6:35 am-9:10 pm
1 stop15h 35m
Medellín Jose Maria Cordova Intl
Wed 5/6
9:45 am-8:02 pm
1 stop9h 17m
$367
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Wed 9/23
9:25 am-9:10 pm
2 stops12h 45m
Medellín Jose Maria Cordova Intl
Wed 9/30
9:45 am-11:05 pm
1 stop12h 20m
$372
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Wed 8/26
9:25 am-9:10 pm
2 stops12h 45m
Medellín Jose Maria Cordova Intl
Wed 10/7
9:45 am-11:05 pm
1 stop12h 20m
$372
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-CTG
JAX-BOG
JAX-MDE
JAX-BAQ
JAX-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-CTG
JAX-BOG
JAX-MDE
JAX-BAQ
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $306). Flying from Jacksonville to South America in July is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 3, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andAmerican Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Crew
8.5
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Overall
7.9
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on April 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 3 airlines flying from Jacksonville to South America
Discover the top 3 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$407 | Average$820 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$425 | Average$849 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$716 | FlexibilityNo cancel fee | On-time81% |