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South America

$141+ Cheap flights from Jacksonville (JAX) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Jacksonville to South America

Cheapest flights from Jacksonville to South America
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
JAX
-
CTG
1 stop7h 30m
American Airlines
Sat 2/284:30 pm
CTG
-
JAX
1 stop16h 33m
American Airlines
Deal found 1/31$283
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:19 pm
JAX
-
CTG
2 stops18h 45m
American Airlines
Tue 5/121:25 pm
CTG
-
JAX
2 stops18h 38m
American Airlines
Deal found 2/2$288
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:41 pm
JAX
-
CTG
1 stop19h 49m
American Airlines
Tue 12/158:00 am
CTG
-
JAX
1 stop15h 59m
American Airlines
Deal found 2/3$290
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:00 am
JAX
-
MDE
1 stop15h 15m
American Airlines
Thu 4/91:50 pm
MDE
-
JAX
1 stop9h 09m
American Airlines
Deal found 1/31$296
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/226:00 am
JAX
-
MDE
1 stop15h 10m
American Airlines
Wed 3/47:00 am
MDE
-
JAX
2 stops14h 59m
American Airlines
Deal found 1/31$301
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
JAX
-
MDE
1 stop15h 40m
United Airlines
Mon 3/210:45 am
MDE
-
JAX
1 stop10h 30m
United Airlines
Deal found 2/1$306
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
JAX
-
MDE
1 stop15h 40m
United Airlines
Tue 3/310:45 am
MDE
-
JAX
2 stops24h 04m
United Airlines
Deal found 2/2$311
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/75:47 pm
JAX
-
MDE
1 stop27h 18m
United Airlines
Tue 3/109:45 am
MDE
-
JAX
1 stop10h 29m
United Airlines
Deal found 1/31$313
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:31 pm
JAX
-
MDE
1 stop28h 34m
United Airlines
Fri 3/610:45 am
MDE
-
JAX
2 stops23h 43m
United Airlines
Deal found 2/1$318
This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:15 am
JAX
-
CTG
1 stop8h 03m
Delta
Tue 5/122:13 pm
CTG
-
JAX
1 stop6h 57m
Delta
Deal found 1/31$329
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:35 am
JAX
-
MDE
1 stop15h 35m
United Airlines
Tue 4/149:45 am
MDE
-
JAX
3 stops33h 17m
United Airlines
Deal found 2/1$330
This KAYAK deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:30 am
JAX
-
CTG
2 stops15h 46m
LATAM Airlines
Tue 12/155:05 am
CTG
-
JAX
2 stops12h 22m
LATAM Airlines
Deal found 2/2$338

Find flight deals from Jacksonville to South America

Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated February 3, 2026.

Round-trip from

$283
(American Airlines)

One-way from

$141
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$590
From Jacksonville to South America
Search Deals
One-way flight from Jacksonville to South America
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($144 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.

Fly from

Jacksonville

Fly to

South America

Route

Depart

Return

Price

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

Sun 2/22

6:00 am-1:30 pm

1 stop7h 30m

Cartagena Rafael Nunez

Sat 2/28

4:30 pm-9:03 am

1 stop16h 33m

$283

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

Sat 5/9

8:19 pm-2:04 pm

2 stops18h 45m

Cartagena Rafael Nunez

Tue 5/12

1:25 pm-11:59 pm

1 stop9h 34m

$288

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

Thu 3/5

8:07 pm-1:30 pm

2 stops17h 23m

Cartagena Rafael Nunez

Thu 3/12

3:15 pm-12:53 pm

2 stops20h 38m

$288

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Fri 4/17

11:00 am-8:15 pm

1 stop10h 15m

Medellín Jose Maria Cordova Intl

Tue 4/21

6:00 am-11:59 pm

1 stop16h 59m

$296

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Mon 2/23

6:25 am-10:05 pm

1 stop15h 40m

Medellín Jose Maria Cordova Intl

Mon 3/2

10:45 am-9:15 pm

1 stop10h 30m

$306

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Mon 2/23

6:25 am-10:05 pm

1 stop15h 40m

Medellín Jose Maria Cordova Intl

Tue 3/3

10:45 am-10:49 am

2 stops24h 04m

$311

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Sun 3/29

9:40 am-9:10 pm

1 stop12h 30m

Medellín Jose Maria Cordova Intl

Thu 4/9

9:45 am-10:36 am

2 stops23h 51m

$311

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Tue 3/31

6:35 am-9:10 pm

1 stop15h 35m

Medellín Jose Maria Cordova Intl

Thu 4/9

9:45 am-10:36 am

2 stops23h 51m

$311

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Sun 2/22

6:25 am-10:05 pm

1 stop15h 40m

Medellín Jose Maria Cordova Intl

Thu 2/26

10:45 am-10:37 am

2 stops23h 52m

$311

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

Fri 2/27

4:55 pm-10:05 pm

2 stops29h 10m

Medellín Jose Maria Cordova Intl

Fri 3/6

10:45 am-10:28 am

2 stops23h 43m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Showing 1-10 of 60 results
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Best time to book a flight from Jacksonville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to South America

What is the cheapest month to book a flight from Jacksonville to South America?

Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $306). Flying from Jacksonville to South America in July is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 3, 2026.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,138 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,138 reviews
Delta
7.9
Good
8,138 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
LATAM Airlines
7.5
Good
1,918 reviews
Delta
7.9
Good
8,138 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,218 reviews
Delta
7.9
Good
8,138 reviews

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to South America?

    If you book a flight to South America from Jacksonville, you will be flying from Jacksonville, which is the city’s only airport. Jacksonville (JAX) is located 11.2 mi from the center of Jacksonville.

  • How long is the flight from Jacksonville to South America?

    Departing from Jacksonville to South America will take you 7h 30m. Jacksonville and South America are separated by a distance of 1440 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Jacksonville to South America?

    Most travelers choose Jacksonville - Medellín Jose Maria Cordova Intl, Jacksonville - Cartagena Rafael Nunez or Jacksonville - Lima J Chavez Intl when deciding on the best route from Jacksonville to South America.

  • Can I find deals for flights from Jacksonville to South America that include hotel bookings?

    Yes. In addition to deals on Jacksonville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to South America.

  • Can I find deals for business class flights from Jacksonville to South America?

    Yes. Cheapflights offers flight deals from Jacksonville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to South America?

    Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $306). Flying from Jacksonville to South America in July is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Jacksonville to South America

Discover the top 3 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$426Average$805FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$488Average$845FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$590Average$740FlexibilityNo cancel feeOn-time81%

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