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South America

$188+ Cheap flights from Jacksonville (JAX) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheap flight deals from Jacksonville to South America

Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated agosto 14, 2025.

Round-trip from

$456
(American Airlines)

One-way from

$188
(Kiwi.com)
From Jacksonville to South America
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One-way flight from Jacksonville to South America
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Find flight deals from Jacksonville to South America

Cheapest flights from Jacksonville to South America
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/289:50 amJAX - MDE
2 stops28h 24mMultiple Airlines
sáb. 10/41:24 amMDE - JAX
3 stops32h 06mMultiple Airlines
Deal found 8/14$474
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/26:20 amJAX - BOG
1 stop13h 55mDelta
jue. 10/99:00 amBOG - JAX
1 stop13h 59mDelta
Deal found 8/14$498
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/156:00 amJAX - MDE
1 stop15h 15mAmerican Airlines
vie. 10/246:00 amMDE - JAX
1 stop16h 59mAmerican Airlines
Deal found 8/12$508
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/216:34 pmJAX - CTG
2 stops18h 51mAmerican Airlines
mié. 9/241:25 pmCTG - JAX
2 stops19h 56mAmerican Airlines
Deal found 8/13$512
This United deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/237:00 amJAX - CLO
2 stops11h 29mMultiple Airlines
dom. 10/269:00 pmCLO - JAX
2 stops17h 34mMultiple Airlines
Deal found 8/13$519
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/210:02 amJAX - BOG
2 stops12h 15mAmerican Airlines
jue. 10/96:30 amBOG - JAX
2 stops12h 06mAmerican Airlines
Deal found 8/14$520
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/2012:50 pmJAX - MDE
2 stops26h 15mJetBlue
sáb. 9/271:30 pmMDE - JAX
2 stops20h 10mJetBlue
Deal found 8/14$520
This Mytrip deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/189:50 amJAX - MDE
2 stops28h 24mMultiple Airlines
sáb. 9/201:24 amMDE - JAX
2 stops14h 13mMultiple Airlines
Deal found 8/12$524
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/211:55 amJAX - BOG
1 stop8h 25mUnited Airlines
mié. 10/812:14 amBOG - JAX
1 stop22h 01mUnited Airlines
Deal found 8/14$525
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/106:00 amJAX - BOG
1 stop8h 05mAmerican Airlines
lun. 10/136:30 amBOG - JAX
1 stop14h 14mAmerican Airlines
Deal found 8/13$532
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/256:00 amJAX - BOG
1 stop16h 17mAmerican Airlines
mar. 9/306:30 amBOG - JAX
1 stop15h 44mAmerican Airlines
Deal found 8/12$534
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/2611:54 amJAX - MDE
1 stop10h 16mUnited Airlines
vie. 10/39:45 amMDE - JAX
1 stop12h 31mUnited Airlines
Deal found 8/12$535

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.

Fly from

Jacksonville

Fly to

South America

Route

Depart

Return

Price

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mar. 1/20

1:23 pm-8:20 pm

1 stop6h 57m

Cartagena Rafael Nunez

mar. 1/27

9:06 am-12:14 am

1 stop15h 08m

$456

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

dom. 9/28

9:50 am-1:14 pm

2 stops28h 24m

Medellín Jose Maria Cordova Intl

sáb. 10/4

1:24 am-10:30 am

3 stops32h 06m

$474

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

jue. 10/2

6:20 am-7:15 pm

1 stop13h 55m

Bogotá El Dorado

jue. 10/9

9:00 am-11:59 pm

1 stop13h 59m

$498

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

dom. 9/21

6:34 pm-12:25 pm

2 stops18h 51m

Cartagena Rafael Nunez

mié. 9/24

1:25 pm-10:21 am

2 stops19h 56m

$512

JacksonvilleCali

JAX - CLO

JAXCLO

Jacksonville

jue. 10/23

7:00 am-5:29 pm

2 stops11h 29m

Cali Alfonso B. Aragon Intl

dom. 10/26

9:00 pm-3:34 pm

2 stops17h 34m

$519

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

sáb. 9/20

12:50 pm-2:05 pm

2 stops26h 15m

Medellín Jose Maria Cordova Intl

sáb. 9/27

1:30 pm-10:40 am

2 stops20h 10m

$520

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

jue. 10/2

10:02 am-9:17 pm

2 stops12h 15m

Bogotá El Dorado

jue. 10/9

6:30 am-7:36 pm

2 stops12h 06m

$520

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

jue. 10/2

11:55 am-7:20 pm

1 stop8h 25m

Bogotá El Dorado

mié. 10/8

12:14 am-11:15 pm

1 stop22h 01m

$525

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mar. 1/20

7:30 am-2:15 pm

1 stop6h 45m

Cartagena Rafael Nunez

lun. 1/26

4:35 am-6:54 pm

2 stops14h 19m

$531

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

vie. 10/10

6:00 am-1:05 pm

1 stop8h 05m

Bogotá El Dorado

lun. 10/13

6:30 am-9:44 pm

1 stop14h 14m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 60 results
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Best time to book a flight from Jacksonville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to South America

What is the cheapest month to book a flight from Jacksonville to South America?

Currently, May is the cheapest month in which you can book a flight from Jacksonville to South America (average of $359). Flying from Jacksonville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to SA?

Find hourly flight availability from Jacksonville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Jacksonville to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated agosto 14, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
LATAM Airlines
7.5
Good
1,840 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to South America?

    If you book a flight to South America from Jacksonville, you will be flying from Jacksonville, which is the city’s only airport. Jacksonville (JAX) is located 11.2 mi from the center of Jacksonville.

  • What are the cheapest airlines to fly from Jacksonville to South America one-way?

    The cheapest airlines for a one-way flight from Jacksonville to South America are JetBlue ($221), American Airlines ($314), and Delta ($320).

  • What are the most popular routes from Jacksonville to South America?

    Most travelers choose Jacksonville - Medellín Jose Maria Cordova Intl, Jacksonville - Buenos Aires Ministro Pistarini or Jacksonville - Lima J Chavez Intl when deciding on the best route from Jacksonville to South America.

  • Can I find deals for flights from Jacksonville to South America that include hotel bookings?

    Yes. In addition to deals on Jacksonville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to South America.

  • Can I find deals for business class flights from Jacksonville to South America?

    Yes. Cheapflights offers flight deals from Jacksonville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to South America?

    Currently, May is the cheapest month in which you can book a flight from Jacksonville to South America (average of $359). Flying from Jacksonville to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Jacksonville to South America

Discover the top 3 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$382Average$852FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$413Average$831FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$415Average$807FlexibilityNo cancel feeOn-time81%

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