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South America

$151+ Cheap flights from Jacksonville (JAX) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
dic. 5 — dic. 121
vie. 12/5
vie. 12/12
1 adult, Economy
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Cheap flight deals from Jacksonville to South America

Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated noviembre 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$456
(American Airlines)

One-way from

$151
(Kiwi.com)
Provider with most accurate pricing for Jacksonville-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Jacksonville-Sao Paulo (SAO) flights.
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From Jacksonville to South America
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One-way flight from Jacksonville to South America
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Find flight deals from Jacksonville to South America

Cheapest flights from Jacksonville to South America
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 5, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/25:05 amJAX - CTG
1 stop9h 12mDelta
vie. 12/125:05 amCTG - JAX
2 stops17h 59mDelta
Deal found 11/5$497
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/46:00 amJAX - CTG
1 stop15h 30mAmerican Airlines
lun. 12/88:00 amCTG - JAX
1 stop15h 59mAmerican Airlines
Deal found 11/4$508
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/26:00 amJAX - CTG
1 stop9h 30mAmerican Airlines
vie. 12/122:30 pmCTG - JAX
1 stop7h 55mAmerican Airlines
Deal found 11/5$523
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/37:00 amJAX - MDE
1 stop15h 05mUnited Airlines
dom. 12/71:15 amMDE - JAX
2 stops20h 17mUnited Airlines
Deal found 11/5$537
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/310:01 amJAX - MDE
1 stop13h 38mAmerican Airlines
dom. 12/71:30 amMDE - JAX
1 stop7h 58mAmerican Airlines
Deal found 11/5$549
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:00 amJAX - MDE
1 stop15h 10mAmerican Airlines
vie. 12/121:30 amMDE - JAX
1 stop7h 58mAmerican Airlines
Deal found 11/4$552
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:00 amJAX - BOG
1 stop6h 40mAmerican Airlines
vie. 12/128:00 amBOG - JAX
1 stop9h 12mAmerican Airlines
Deal found 11/5$554
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:59 pmJAX - MDE
2 stops27h 06mUnited Airlines
vie. 12/121:15 amMDE - JAX
1 stop9h 19mUnited Airlines
Deal found 11/4$557
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/43:40 pmJAX - CTG
2 stops31h 20mUnited Airlines
lun. 12/86:25 amCTG - JAX
2 stops15h 23mUnited Airlines
Deal found 11/4$559
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:05 amJAX - BOG
2 stops14h 15mDelta
vie. 12/129:00 amBOG - JAX
1 stop13h 04mDelta
Deal found 11/5$571
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/25:05 amJAX - LIM
2 stops15h 10mDelta
jue. 12/1111:40 pmLIM - JAX
1 stop15h 23mDelta
Deal found 11/4$595
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/264:57 pmJAX - MDE
1 stop29h 08mUnited Airlines
mar. 12/210:45 amMDE - JAX
2 stops34h 47mUnited Airlines
Deal found 11/4$599

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 5, 2025.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.

Fly from

Jacksonville

Fly to

South America

Route

Depart

Return

Price

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mié. 1/21

6:00 am-1:30 pm

1 stop7h 30m

Cartagena Rafael Nunez

mié. 1/28

2:30 pm-11:59 pm

1 stop9h 29m

$456

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

jue. 1/22

7:30 am-2:17 pm

1 stop6h 47m

Cartagena Rafael Nunez

jue. 1/29

3:32 pm-11:59 pm

1 stop8h 27m

$456

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

jue. 1/22

6:00 am-3:30 pm

2 stops9h 30m

Cartagena Rafael Nunez

jue. 1/29

4:30 pm-11:03 am

2 stops18h 33m

$461

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mar. 12/2

5:05 am-2:17 pm

1 stop9h 12m

Cartagena Rafael Nunez

vie. 12/12

5:05 am-11:04 pm

2 stops17h 59m

$497

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

sáb. 1/31

8:10 pm-2:45 pm

2 stops18h 35m

Medellín Jose Maria Cordova Intl

sáb. 2/7

2:25 pm-9:08 am

2 stops18h 43m

$510

JacksonvilleMedellín

JAX - MDE

JAXMDE

Jacksonville

sáb. 1/31

11:40 am-10:05 pm

1 stop10h 25m

Medellín Jose Maria Cordova Intl

sáb. 2/7

10:45 am-9:47 pm

1 stop11h 02m

$518

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

jue. 4/30

7:00 am-7:20 pm

1 stop13h 20m

Bogotá El Dorado

dom. 5/3

12:14 am-3:42 pm

1 stop14h 28m

$522

JacksonvilleBogotá

JAX - BOG

JAXBOG

Jacksonville

jue. 4/30

6:30 am-1:50 pm

1 stop8h 20m

Bogotá El Dorado

lun. 5/4

2:55 pm-12:02 am

1 stop8h 07m

$522

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mar. 12/2

6:00 am-3:30 pm

1 stop9h 30m

Cartagena Rafael Nunez

vie. 12/12

2:30 pm-10:25 pm

1 stop7h 55m

$523

JacksonvilleCartagena

JAX - CTG

JAXCTG

Jacksonville

mié. 1/21

5:30 am-2:17 pm

1 stop8h 47m

Cartagena Rafael Nunez

mar. 1/27

4:35 am-8:54 pm

2 stops16h 19m

$531

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
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Best time to book a flight from Jacksonville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to South America

What is the cheapest month to book a flight from Jacksonville to South America?

Currently, January is the cheapest month in which you can book a flight from Jacksonville to South America (average of $236). Flying from Jacksonville to South America in July is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from JAX to SA?

Find hourly flight availability from Jacksonville to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 5, 2025.

One of the essential ways to save on airfare from Jacksonville to South America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 11% on airfare.

What is the cheapest day to fly from Jacksonville to South America?

Use this chart to determine the cheapest time to fly round-trip from Jacksonville to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Jacksonville to South America flight should consider departing on Saturday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated noviembre 5, 2025.
Get a feel of what it's like to fly with Delta, LATAM Airlines, and American Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
LATAM Airlines
7.5
Good
1,874 reviews
Delta
7.9
Good
8,004 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,039 reviews
Delta
7.9
Good
8,004 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Jacksonville to South America?

    If you book a flight to South America from Jacksonville, you will be flying from Jacksonville, which is the city’s only airport. Jacksonville (JAX) is located 11.2 mi from the center of Jacksonville.

  • How long is the flight from Jacksonville to South America?

    Departing from Jacksonville to South America will take you 6h 47m. Jacksonville and South America are separated by a distance of 1440 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Jacksonville to South America?

    Most travelers choose Jacksonville - Buenos Aires Ministro Pistarini, Jacksonville - Quito Mariscal Sucr or Jacksonville - Lima J Chavez Intl when deciding on the best route from Jacksonville to South America.

  • Can I find deals for flights from Jacksonville to South America that include hotel bookings?

    Yes. In addition to deals on Jacksonville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to South America.

  • Can I find deals for business class flights from Jacksonville to South America?

    Yes. Cheapflights offers flight deals from Jacksonville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Jacksonville to South America?

    Currently, January is the cheapest month in which you can book a flight from Jacksonville to South America (average of $236). Flying from Jacksonville to South America in July is currently the most expensive (average of $602). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Jacksonville to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Jacksonville to South America

Discover the top 3 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$478Average$927FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$514Average$785FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$588Average$782FlexibilityNo cancel feeOn-time81%

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