$205+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Jacksonville to South America
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:00 am -
1 stop15h 10m
Wed 11/1110:40 am -
1 stop12h 35m
Deal found 9/9![United Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:44 am -
2 stops13h 50m
Tue 11/107:30 am -
2 stops11h 14m
Deal found 9/8![American Airlines logo]()
$401
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:29 pm -
1 stop28h 41m
Tue 11/1010:40 am -
1 stop12h 35m
Deal found 9/8![United Airlines logo]()
$405
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:05 am -
1 stop5h 39m
Fri 11/61:49 pm -
1 stop6h 08m
Deal found 9/8![JetBlue logo]()
$411
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:45 am -
1 stop5h 50m
Wed 10/281:35 pm -
1 stop20h 17m
Deal found 9/9![American Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:17 pm -
2 stops17h 18m
Fri 11/62:35 pm -
1 stop7h 55m
Deal found 9/11![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:17 pm -
2 stops17h 18m
Mon 11/24:37 pm -
2 stops17h 29m
Deal found 9/12![American Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/204:45 pm -
2 stops29h 25m
Wed 11/410:40 am -
1 stop12h 35m
Deal found 9/13![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:15 pm -
2 stops17h 20m
Sun 11/12:35 pm -
1 stop9h 47m
Deal found 9/10![American Airlines logo]()
$468
This Orbitz deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:19 am -
1 stop6h 33m
Sat 10/1012:37 pm -
1 stop6h 17m
Deal found 9/8![JetBlue logo]()
$469
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:05 am -
1 stop5h 39m
Sun 11/11:49 pm -
1 stop6h 08m
Deal found 9/10![JetBlue logo]()
$484
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:15 pm -
2 stops17h 20m
Sat 10/101:35 pm -
2 stops18h 33m
Deal found 9/8![American Airlines logo]()
$487
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:29 pm -
1 stop28h 41m
Tue 11/1010:40 am -
1 stop12h 35m
Deal found 9/8![United Airlines logo]()
$405
This JetBlue deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:05 am -
1 stop5h 39m
Fri 11/61:49 pm -
1 stop6h 08m
Deal found 9/11![JetBlue logo]()
$411
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/96:00 am -
2 stops15h 26m
Thu 2/117:00 am -
1 stop15h 30m
Deal found 9/10![American Airlines logo]()
$424
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2010:00 am -
1 stop20h 35m
Tue 1/263:30 am -
2 stops14h 45m
Deal found 9/10![Multiple Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/239:57 am -
2 stops10h 13m
Sat 1/308:35 am -
2 stops12h 04m
Deal found 9/10![Delta logo]()
$695
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:11 am -
2 stops38h 59m
Wed 11/1110:40 am -
2 stops23h 51m
Deal found 9/9![United Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/165:16 pm -
2 stops20h 19m
Wed 3/313:15 pm -
1 stop7h 44m
Deal found 9/11![American Airlines logo]()
$458
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:17 pm -
2 stops17h 18m
Mon 11/24:37 pm -
2 stops17h 29m
Deal found 9/12![American Airlines logo]()
$464
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:58 pm -
2 stops17h 32m
Sun 11/112:48 am -
2 stops17h 55m
Deal found 9/9![LATAM Airlines logo]()
$1,035
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:29 pm -
1 stop28h 41m
Sun 11/1510:40 am -
1 stop29h 43m
Deal found 9/9![United Airlines logo]()
$505
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/237:10 pm -
1 stop10h 55m
Sat 1/307:00 am -
1 stop11h 15m
Deal found 9/11![Multiple Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:12 pm -
2 stops19h 23m
Sat 10/101:35 pm -
1 stop9h 24m
Deal found 9/8![American Airlines logo]()
$468
This GOL deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure GOL is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:00 am -
2 stops14h 20m
Sat 1/26:00 pm -
2 stops19h 20m
Deal found 9/13![GOL logo]()
$1,226
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:15 pm -
1 stop11h 20m
Sat 11/145:20 pm -
1 stop16h 09m
Deal found 9/13![Multiple Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/56:28 pm -
2 stops19h 07m
Sun 2/142:30 pm -
2 stops22h 23m
Deal found 9/10![American Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:58 pm -
2 stops29h 12m
Fri 10/239:45 am -
1 stop12h 35m
Deal found 9/10![United Airlines logo]()
$559
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:09 pm -
2 stops22h 46m
Sun 11/13:55 pm -
1 stop8h 01m
Deal found 9/9![Delta logo]()
$699
This Aviatur deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aviatur is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:06 pm -
1 stop17h 19m
Sun 12/1311:05 pm -
1 stop11h 32m
Deal found 9/9![Multiple Airlines logo]()
$585
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:25 pm -
2 stops18h 10m
Sun 10/251:35 pm -
1 stop20h 17m
Deal found 9/12![American Airlines logo]()
$497
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:58 pm -
2 stops29h 12m
Sun 10/259:45 am -
2 stops23h 46m
Deal found 9/9![United Airlines logo]()
$559
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/97:10 pm -
1 stop11h 25m
Sat 1/165:20 pm -
1 stop15h 50m
Deal found 9/9![Multiple Airlines logo]()
$592
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:00 am -
1 stop15h 10m
Thu 11/2610:40 am -
1 stop29h 43m
Deal found 9/10![United Airlines logo]()
$571
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/115:30 am -
2 stops16h 20m
Tue 2/1612:10 pm -
1 stop11h 52m
Deal found 9/10![Delta logo]()
$775
This Orbitz deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:30 pm -
2 stops19h 40m
Fri 11/276:55 pm -
2 stops15h 14m
Deal found 9/11![Multiple Airlines logo]()
$627
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:25 am -
2 stops17h 35m
Wed 11/1112:15 am -
2 stops13h 07m
Deal found 9/8![Delta logo]()
$780
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:46 pm -
2 stops18h 14m
Tue 1/197:05 pm -
2 stops17h 16m
Deal found 9/10![LATAM Airlines logo]()
$1,035
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:24 pm -
2 stops18h 11m
Sat 11/286:00 am -
1 stop16h 47m
Deal found 9/9![American Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:53 pm -
2 stops13h 07m
Wed 11/118:20 am -
2 stops13h 34m
Deal found 9/12![Delta logo]()
$800
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:30 am -
2 stops16h 05m
Sun 11/88:15 am -
2 stops27h 13m
Deal found 9/9![United Airlines logo]()
$665
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/119:45 am -
1 stop10h 25m
Mon 1/257:00 am -
1 stop11h 15m
Deal found 9/9![Multiple Airlines logo]()
$665
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated September 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/204:45 pm -
2 stops29h 25m
Wed 11/410:40 am -
1 stop12h 35m
Deal found 9/13![United Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:45 am -
1 stop5h 50m
Wed 10/281:35 pm -
1 stop20h 17m
Deal found 9/9![American Airlines logo]()
$440
This Faresmojo deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:19 am -
1 stop8h 00m
Mon 10/51:30 pm -
1 stop7h 59m
Deal found 9/8![JetBlue logo]()
$495
This Orbitz deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:19 am -
1 stop6h 33m
Sat 10/1012:37 pm -
1 stop6h 17m
Deal found 9/8![JetBlue logo]()
$469
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:15 pm -
2 stops17h 20m
Sat 10/101:35 pm -
2 stops18h 33m
Deal found 9/8![American Airlines logo]()
$487
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:00 pm -
1 stop12h 35m
Sat 10/175:25 pm -
1 stop15h 05m
Deal found 9/12![Multiple Airlines logo]()
$516
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:15 pm -
2 stops17h 20m
Sun 11/12:35 pm -
1 stop9h 47m
Deal found 9/10![American Airlines logo]()
$468
This Expedia deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:05 am -
1 stop5h 39m
Sun 11/11:49 pm -
1 stop6h 08m
Deal found 9/10![JetBlue logo]()
$484
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 pm -
1 stop12h 20m
Tue 11/35:20 pm -
1 stop21h 18m
Deal found 9/12![Multiple Airlines logo]()
$524
This JetBlue deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:05 am -
1 stop5h 39m
Fri 11/61:49 pm -
1 stop6h 08m
Deal found 9/8![JetBlue logo]()
$411
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:17 pm -
2 stops17h 18m
Fri 11/62:35 pm -
1 stop7h 55m
Deal found 9/11![American Airlines logo]()
$454
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:17 pm -
2 stops17h 18m
Mon 11/24:37 pm -
2 stops17h 29m
Deal found 9/12![American Airlines logo]()
$464
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:46 pm -
3 stops37h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$205
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:00 am -
1 stop15h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![United Airlines logo]()
$208
This LATAM Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:18 am -
2 stops22h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![LATAM Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:13 pm -
3 stops53h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$218
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:58 pm -
2 stops29h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$224
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:45 am -
1 stop13h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$228
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/710:00 am -
1 stop20h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:12 pm -
2 stops21h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$237
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:45 pm -
1 stop12h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$249
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 am -
2 stops39h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$251
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:00 am -
2 stops17h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:20 pm -
3 stops48h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$254
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated September 13, 2026.
Round-trip from | $398 (United Airlines) |
|---|---|
One-way from | $201 (Kiwi.com) |
Popular in | September |
Cheapest in | April |
Average price | $795 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Sat 10/3
7:46 pm-8:15 am
3 stops37h 29m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$205
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Sun 11/1
7:00 am-10:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Sat 10/3
4:58 pm-9:10 pm
2 stops29h 12m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Mon 9/21
7:45 am-8:15 pm
1 stop13h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$228
JacksonvilleQuito
JAX Jacksonville - UIO Quito Mariscal Sucr
JAXUIO
Jacksonville
Sun 2/7
10:00 am-6:35 am
1 stop20h 35m
Quito Mariscal Sucr
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$229
JacksonvilleBogotá
JAX Jacksonville - BOG Bogotá El Dorado
JAXBOG
Jacksonville
Tue 11/10
4:45 pm-5:30 am
1 stop12h 45m
Bogotá El Dorado
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Mon 9/21
6:40 am-9:10 pm
2 stops39h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$251
JacksonvilleCartagena
JAX Jacksonville - CTG Cartagena Rafael Nunez
JAXCTG
Jacksonville
Fri 10/2
7:00 am-11:00 pm
2 stops17h 00m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$252
JacksonvilleMedellín
JAX Jacksonville - MDE Medellín Jose Maria Cordova Intl
JAXMDE
Jacksonville
Tue 10/13
3:20 pm-2:45 pm
3 stops48h 25m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
JacksonvilleCartagena
JAX Jacksonville - CTG Cartagena Rafael Nunez
JAXCTG
Jacksonville
Fri 10/2
7:37 pm-12:35 pm
1 stop17h 58m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$260
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-CTG
JAX-MDE
JAX-UIO
JAX-BOG
JAX-GRU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-CTG
JAX-MDE
JAX-UIO
JAX-BOG
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, April is the cheapest month in which you can book a flight from Jacksonville to South America (average of $627). Flying from Jacksonville to South America in December is currently the most expensive (average of $871). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Jacksonville to South America?
To ensure you get the cheapest price possible for a flight from Jacksonville to South America, you should look to book at least 23 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 13, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Food
7.2
Crew
8.5
Boarding
8.1
Comfort
7.8
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on September 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 5 airlines flying from Jacksonville to South America
Discover the top 5 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$383 | Average$995 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$392 | Average$664 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$425 | Average$840 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$687 | FlexibilityNo cancel fee | On-time81% |