$173+ Cheap flights from Jacksonville (JAX) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — BOG
Aug 16 — Aug 231
Round-trip
1 adult, Economy
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Find cheap flights from Jacksonville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Jacksonville to South AmericaExplore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
Explore the most affordable flight options available from Jacksonville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
1 stop9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 7/13![American Airlines logo]()
$321
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:18 am
JAX
- CTG
1 stop6h 15m
American Airlines
Wed 11/184:15 pm
CTG
- JAX
1 stop7h 44m
American Airlines
Deal found 7/14![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:05 pm
JAX
- CTG
2 stops21h 10m
American Airlines
Thu 8/271:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 7/13![American Airlines logo]()
$334
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/12![JetBlue logo]()
$357
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/13![JetBlue logo]()
$377
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:36 pm
JAX
- CTG
1 stop17h 59m
American Airlines
Sat 10/171:35 pm
CTG
- JAX
2 stops18h 33m
American Airlines
Deal found 7/13![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:45 am
JAX
- CTG
1 stop5h 50m
American Airlines
Thu 9/241:35 pm
CTG
- JAX
1 stop9h 24m
American Airlines
Deal found 7/13![American Airlines logo]()
$394
This Cheapflightsfares deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Thu 9/1712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/13![JetBlue logo]()
$398
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
JAX
- CTG
2 stops9h 15m
American Airlines
Tue 8/183:15 pm
CTG
- JAX
1 stop7h 19m
American Airlines
Deal found 7/14![American Airlines logo]()
$399
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Sun 9/2712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/12![JetBlue logo]()
$401
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Thu 11/1910:40 am
MDE
- JAX
1 stop12h 33m
United Airlines
Deal found 7/15![United Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Wed 11/1810:40 am
MDE
- JAX
2 stops24h 31m
United Airlines
Deal found 7/15![United Airlines logo]()
$422
Best flights from Jacksonville to South AmericaDiscover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
Discover carefully curated flight deals from Jacksonville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
1 stop9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 7/14![American Airlines logo]()
$321
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/12![JetBlue logo]()
$357
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Thu 11/1910:40 am
MDE
- JAX
1 stop12h 33m
United Airlines
Deal found 7/15![United Airlines logo]()
$417
This Avianca deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:36 pm
JAX
- GYE
1 stop18h 04m
Multiple Airlines
Thu 9/38:00 pm
GYE
- JAX
1 stop19h 34m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:15 am
JAX
- MDE
2 stops14h 50m
Delta
Tue 11/105:05 am
MDE
- JAX
2 stops15h 34m
Delta
Deal found 7/13![Delta logo]()
$493
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:05 pm
JAX
- CTG
2 stops21h 10m
American Airlines
Thu 8/271:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 7/13![American Airlines logo]()
$334
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/13![JetBlue logo]()
$377
This Avianca deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:25 pm
JAX
- GYE
1 stop20h 15m
Multiple Airlines
Thu 9/174:05 pm
GYE
- JAX
1 stop21h 21m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$431
This Cheapflightsfares deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Thu 9/1712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/12![JetBlue logo]()
$398
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Wed 11/410:40 am
MDE
- JAX
1 stop12h 33m
United Airlines
Deal found 7/11![United Airlines logo]()
$462
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:19 am
JAX
- GYE
1 stop8h 55m
JetBlue
Sun 9/2712:30 pm
GYE
- JAX
1 stop8h 59m
JetBlue
Deal found 7/12![JetBlue logo]()
$401
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:05 am
JAX
- CTG
2 stops16h 55m
United Airlines
Mon 8/319:45 am
CTG
- JAX
2 stops36h 55m
United Airlines
Deal found 7/13![United Airlines logo]()
$464
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:30 am
JAX
- BOG
2 stops12h 40m
Delta
Thu 12/1010:45 am
BOG
- JAX
2 stops13h 17m
Delta
Deal found 7/12![Delta logo]()
$565
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:25 am
JAX
- MDE
2 stops12h 45m
United Airlines
Wed 11/1810:40 am
MDE
- JAX
2 stops24h 31m
United Airlines
Deal found 7/15![United Airlines logo]()
$487
This Expedia deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:46 pm
JAX
- GRU
2 stops34h 49m
LATAM Airlines
Wed 1/611:55 pm
GRU
- JAX
2 stops26h 07m
LATAM Airlines
Deal found 7/12![LATAM Airlines logo]()
$1,194
This oojo deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:55 pm
JAX
- AEP
2 stops22h 05m
GOL
Sat 10/173:40 am
AEP
- JAX
2 stops17h 31m
GOL
Deal found 7/16![GOL logo]()
$1,286
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:15 am
JAX
- BOG
2 stops11h 35m
Delta
Mon 10/128:40 am
BOG
- JAX
2 stops14h 16m
Delta
Deal found 7/12![Delta logo]()
$589
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:25 am
JAX
- MDE
2 stops36h 45m
United Airlines
Wed 11/1810:40 am
MDE
- JAX
2 stops27h 25m
United Airlines
Deal found 7/15![United Airlines logo]()
$504
This JetBlue deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 8/1912:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/14![JetBlue logo]()
$532
This Delta deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am
JAX
- BOG
1 stop8h 40m
Delta
Wed 9/302:55 pm
BOG
- JAX
1 stop18h 14m
Delta
Deal found 7/16![Delta logo]()
$596
This Expedia deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:05 am
JAX
- CLO
2 stops28h 20m
Multiple Airlines
Tue 8/119:35 pm
CLO
- JAX
1 stop17h 59m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$660
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Wed 9/169:45 am
MDE
- JAX
2 stops36h 35m
United Airlines
Deal found 7/15![United Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:01 am
JAX
- GYE
2 stops16h 38m
American Airlines
Wed 8/126:00 am
GYE
- JAX
2 stops15h 58m
American Airlines
Deal found 7/13![American Airlines logo]()
$675
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:05 am
JAX
- BOG
2 stops13h 45m
Delta
Mon 10/198:40 am
BOG
- JAX
2 stops22h 57m
Delta
Deal found 7/12![Delta logo]()
$599
This Avianca deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:35 pm
JAX
- CLO
1 stop9h 10m
Multiple Airlines
Tue 8/186:15 am
CLO
- JAX
2 stops12h 42m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:25 am
JAX
- BOG
2 stops10h 25m
Delta
Sun 9/132:55 pm
BOG
- JAX
1 stop16h 42m
Delta
Deal found 7/14![Delta logo]()
$605
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Wed 9/99:45 am
MDE
- JAX
3 stops34h 09m
United Airlines
Deal found 7/13![United Airlines logo]()
$553
This Avianca deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:35 pm
JAX
- CLO
1 stop9h 10m
Multiple Airlines
Mon 8/176:15 am
CLO
- JAX
2 stops12h 42m
Multiple Airlines
Deal found 7/16![Multiple Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:30 am
JAX
- MDE
2 stops14h 40m
United Airlines
Mon 9/219:45 am
MDE
- JAX
3 stops34h 09m
United Airlines
Deal found 7/13![United Airlines logo]()
$553
This Avianca deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:35 pm
JAX
- CLO
1 stop9h 10m
Multiple Airlines
Tue 8/115:55 am
CLO
- JAX
2 stops13h 02m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$703
Last-minute flights from Jacksonville to South AmericaDiscover last-minute flight deals from Jacksonville to South America. Data last updated July 17, 2026 and is based on user searches.
Discover last-minute flight deals from Jacksonville to South America. Data last updated July 17, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 8/2012:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/14![JetBlue logo]()
$459
This Justfly.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Wed 8/1212:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/14![JetBlue logo]()
$455
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
JAX
- CTG
2 stops9h 15m
American Airlines
Tue 8/183:15 pm
CTG
- JAX
1 stop7h 19m
American Airlines
Deal found 7/14![American Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
JAX
- CTG
1 stop8h 15m
Delta
Tue 8/182:30 pm
CTG
- JAX
1 stop8h 25m
Delta
Deal found 7/14![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:05 pm
JAX
- CTG
2 stops21h 10m
American Airlines
Thu 8/271:35 pm
CTG
- JAX
2 stops18h 29m
American Airlines
Deal found 7/13![American Airlines logo]()
$334
This Justfly.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Sat 8/2912:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/14![JetBlue logo]()
$419
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/274:45 pm
JAX
- MDE
2 stops29h 25m
United Airlines
Tue 9/89:45 am
MDE
- JAX
2 stops27h 20m
United Airlines
Deal found 7/13![United Airlines logo]()
$417
This Avianca deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:36 pm
JAX
- GYE
1 stop18h 04m
Multiple Airlines
Thu 9/38:00 pm
GYE
- JAX
1 stop19h 34m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
JAX
- CTG
1 stop9h 15m
American Airlines
Wed 9/21:35 pm
CTG
- JAX
1 stop9h 59m
American Airlines
Deal found 7/13![American Airlines logo]()
$321
This JetBlue deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/12![JetBlue logo]()
$357
This JetBlue deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:10 am
JAX
- CTG
1 stop5h 25m
JetBlue
Thu 9/312:35 pm
CTG
- JAX
1 stop6h 22m
JetBlue
Deal found 7/13![JetBlue logo]()
$377
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:00 am
JAX
- CTG
1 stop5h 35m
American Airlines
Thu 9/33:15 pm
CTG
- JAX
2 stops19h 41m
American Airlines
Deal found 7/15![American Airlines logo]()
$423
One-way flights from Jacksonville to South AmericaSearch for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
Search for one-way flight options from Jacksonville to South America. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/17:00 am
JAX
- MDE
1 stop15h 10m
United Airlines
Deal found 7/13![United Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:49 am
JAX
- MDE
2 stops22h 26m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:14 am
JAX
- BOG
1 stop10h 11m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/712:48 pm
JAX
- MDE
2 stops20h 27m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:48 pm
JAX
- BOG
2 stops29h 19m
Multiple Airlines
Deal found 7/14![Multiple Airlines logo]()
$192
This Avianca deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:35 pm
JAX
- GYE
1 stop15h 10m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:58 pm
JAX
- MDE
1 stop5h 41m
American Airlines
Deal found 7/16![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:05 pm
JAX
- BOG
2 stops26h 05m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:29 pm
JAX
- MDE
2 stops38h 46m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$213
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:05 am
JAX
- MDE
1 stop15h 05m
United Airlines
Deal found 7/13![United Airlines logo]()
$214
This KAYAK deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:05 am
JAX
- CLO
1 stop6h 45m
JetBlue
Deal found 7/13![JetBlue logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 pm
JAX
- BOG
2 stops26h 05m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$222
Find flight deals from Jacksonville to South America
Keep the following information in mind while searching for Jacksonville to South America flight deals. Data was last updated July 17, 2026.
Round-trip from | $321 (American Airlines) |
|---|---|
One-way from | $173 (United Airlines) |
Popular in | March |
Cheapest in | April |
Average price | $686 |
Cheapflights Fare Finder
Customize your flight search to find flights from Jacksonville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
Use the filters below to find and compare flights from Jacksonville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 8/29
6:00 am-2:15 pm
1 stop9h 15m
Cartagena Rafael Nunez
Wed 9/2
1:35 pm-12:34 am
1 stop9h 59m
$321
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sat 8/22
6:05 pm-2:15 pm
2 stops21h 10m
Cartagena Rafael Nunez
Thu 8/27
1:35 pm-9:04 am
2 stops18h 29m
$334
Quickest round-trip
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Sun 8/30
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Thu 9/3
12:35 pm-7:57 pm
1 stop6h 22m
$357
JacksonvilleCartagena
JAX - CTG
JAXCTG
Jacksonville
Mon 8/31
7:10 am-11:35 am
1 stop5h 25m
Cartagena Rafael Nunez
Thu 9/3
12:35 pm-7:57 pm
1 stop6h 22m
$377
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 9/14
7:19 am-3:14 pm
1 stop8h 55m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
12:30 pm-10:29 pm
1 stop8h 59m
$398
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Wed 9/23
7:19 am-3:14 pm
1 stop8h 55m
Guayaquil Jose Joaquin de Olmedo
Sun 9/27
12:30 pm-10:29 pm
1 stop8h 59m
$401
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Tue 11/10
7:00 am-10:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Thu 11/19
10:40 am-11:13 pm
1 stop12h 33m
$417
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Thu 8/27
5:36 pm-10:40 am
1 stop18h 04m
Guayaquil Jose Joaquin de Olmedo
Thu 9/3
8:00 pm-4:34 pm
1 stop19h 34m
$423
JacksonvilleGuayaquil
JAX - GYE
JAXGYE
Jacksonville
Mon 9/14
3:25 pm-10:40 am
1 stop20h 15m
Guayaquil Jose Joaquin de Olmedo
Thu 9/17
4:05 pm-2:26 pm
1 stop21h 21m
$431
JacksonvilleMedellín
JAX - MDE
JAXMDE
Jacksonville
Mon 11/2
7:00 am-10:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Wed 11/4
10:40 am-11:13 pm
1 stop12h 33m
$462
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Jacksonville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Jacksonville with our price prediction graph.
JAX-MDE
JAX-BOG
JAX-CTG
JAX-GYE
JAX-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Jacksonville to South America
JAX-0SA
JAX-MDE
JAX-BOG
JAX-CTG
JAX-GYE
What is the cheapest month to book a flight from Jacksonville to South America?
Currently, February is the cheapest month in which you can book a flight from Jacksonville to South America (average of $154). Flying from Jacksonville to South America in January is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated July 17, 2026.
Get a feel of what it's like to fly with Delta,LATAM Airlines, andUnited Airlines from Jacksonville to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.8
Food
7.2
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Jacksonville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Jacksonville to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Jacksonville to South America by cabin class
Find flights from Jacksonville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Jacksonville and South America flights
Browse other Jacksonville and South America flight options. Last updated on July 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Jacksonville to South America flights
Consider these flights traveling from Jacksonville to South America.
Top 4 airlines flying from Jacksonville to South America
Discover the top 4 airlines that operate flights from Jacksonville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$154 | Average$367 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$407 | Average$964 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$425 | Average$832 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$590 | Average$714 | FlexibilityNo cancel fee | On-time81% |