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Sioux Falls

$249+ Cheap flights from Mississippi to Sioux Falls (FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/28. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Mississippi to Sioux Falls

Cheapest flights from Mississippi to Sioux Falls
Explore the most affordable flight options available from Mississippi to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:15 amMEM - FSD
1 stop7h 25mAmerican Airlines
Wed 12/3110:41 amFSD - MEM
1 stop6h 17mAmerican Airlines
Deal found 12/12$386
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:32 amBTR - FSD
1 stop6h 56mAmerican Airlines
Tue 12/305:16 pmFSD - BTR
1 stop5h 21mAmerican Airlines
Deal found 12/13$540
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:15 pmGPT - FSD
2 stops17h 37mUnited Airlines
Sat 1/177:30 amFSD - GPT
2 stops12h 18mUnited Airlines
Deal found 12/12$542
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:15 pmGPT - FSD
2 stops28h 41mUnited Airlines
Sat 1/177:30 amFSD - GPT
2 stops12h 18mUnited Airlines
Deal found 12/12$552
This American Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:13 amMOB - FSD
1 stop7h 15mAmerican Airlines
Fri 1/27:29 pmFSD - MOB
2 stops14h 56mAmerican Airlines
Deal found 12/12$607
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:45 pmMOB - FSD
2 stops15h 31mAmerican Airlines
Wed 12/3110:41 amFSD - MOB
2 stops23h 44mAmerican Airlines
Deal found 12/13$618
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:55 pmMOB - FSD
1 stop6h 11mAmerican Airlines
Sun 1/41:16 pmFSD - MOB
1 stop5h 41mAmerican Airlines
Deal found 12/13$619
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:30 amMOB - FSD
2 stops10h 21mUnited Airlines
Sun 1/48:50 amFSD - MOB
2 stops27h 34mUnited Airlines
Deal found 12/13$623
This United Airlines deal was found by Cheapflights users on 12/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:35 amBTR - FSD
2 stops10h 25mUnited Airlines
Tue 12/307:30 amFSD - BTR
2 stops11h 53mUnited Airlines
Deal found 12/12$631
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:57 amMOB - FSD
2 stops13h 02mAmerican Airlines
Sun 12/287:29 pmFSD - MOB
2 stops14h 56mAmerican Airlines
Deal found 12/13$694
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:02 pmMOB - FSD
1 stop5h 38mDelta
Sun 1/45:16 amFSD - MOB
1 stop8h 04mDelta
Deal found 12/13$719
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:19 amGPT - FSD
1 stop7h 09mAmerican Airlines
Fri 1/21:24 pmFSD - GPT
1 stop5h 32mAmerican Airlines
Deal found 12/13$719

Find flight deals from Mississippi to Sioux Falls

Keep the following information in mind while searching for Mississippi to Sioux Falls flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
Search Deals
From Mississippi to Sioux Falls Joe Foss Field
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Mississippi to Sioux Falls that are best for you.

Fly from

Mississippi

Fly to

Sioux Falls

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 3/5

6:00 am-12:15 pm

1 stop6h 15m

Sioux Falls Joe Foss Field

Thu 3/12

1:34 pm-8:43 pm

1 stop7h 09m

$269

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Fri 1/9

6:32 am-5:45 pm

2 stops11h 13m

Sioux Falls Joe Foss Field

Sun 1/11

5:35 pm-11:33 pm

1 stop5h 58m

$284

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Fri 1/9

10:44 am-8:24 pm

2 stops9h 40m

Sioux Falls Joe Foss Field

Mon 1/12

1:40 pm-9:59 pm

2 stops8h 19m

$289

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Fri 1/9

1:57 pm-11:44 pm

2 stops9h 47m

Sioux Falls Joe Foss Field

Sun 1/11

7:30 am-3:58 pm

2 stops8h 28m

$289

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Fri 1/9

3:20 pm-10:04 pm

1 stop6h 44m

Sioux Falls Joe Foss Field

Mon 1/12

5:35 pm-10:59 pm

1 stop5h 24m

$314

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 1/8

4:15 pm-11:44 pm

1 stop7h 29m

Sioux Falls Joe Foss Field

Sun 1/11

9:00 am-2:20 pm

1 stop5h 20m

$339

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Wed 1/14

7:00 am-8:24 pm

2 stops13h 24m

Sioux Falls Joe Foss Field

Sat 1/17

7:30 am-6:24 pm

2 stops10h 54m

$348

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Wed 12/24

9:15 am-4:40 pm

1 stop7h 25m

Sioux Falls Joe Foss Field

Wed 12/31

10:41 am-4:58 pm

1 stop6h 17m

$386

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 3/5

8:56 am-7:06 pm

2 stops10h 10m

Sioux Falls Joe Foss Field

Thu 3/12

7:41 pm-11:59 pm

1 stop4h 18m

$412

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Sat 1/10

5:13 pm-10:47 am

2 stops17h 34m

Sioux Falls Joe Foss Field

Sat 1/17

7:30 am-7:48 pm

2 stops12h 18m

$492

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 25 results
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Best time to book a flight from Mississippi to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Sioux Falls
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Sioux Falls from Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Sioux Falls from Mississippi.

  • How long is the flight from Mississippi to Sioux Falls?

    There are many flights that can get you from Mississippi to Sioux Falls in 6h 15m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Mississippi and Sioux Falls is about 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Mississippi to Sioux Falls?

    When deciding which route to take from Mississippi to Sioux Falls consider Memphis - Sioux Falls Joe Foss Field, Mobile - Sioux Falls Joe Foss Field or Baton Rouge Ryan - Sioux Falls Joe Foss Field as they are the most popular.

  • Can I find deals for flights from Mississippi to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Mississippi to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Sioux Falls.

  • Can I find deals for business class flights from Mississippi to Sioux Falls?

    Yes. Cheapflights offers flight deals from Mississippi to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Alternative routes for Mississippi to Sioux Falls

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Top airline flying from Mississippi to Sioux Falls

Discover the top airline that operate flights from Mississippi to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$451FlexibilityNo cancel feeOn-time71%

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