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Sioux Falls

$175+ Cheap flights from Mississippi to Sioux Falls (FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Mississippi to Sioux Falls

Cheapest flights from Mississippi to Sioux Falls
Explore the most affordable flight options available from Mississippi to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:40 pmMEM - FSD
1 stop4h 20mDelta
Mon 11/174:19 pmFSD - MEM
1 stop6h 14mDelta
Deal found 10/29$279
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:16 amMEM - FSD
1 stop6h 57mAmerican Airlines
Tue 11/257:16 pmFSD - MEM
1 stop4h 43mAmerican Airlines
Deal found 10/29$294
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:25 pmBTR - FSD
1 stop4h 45mAmerican Airlines
Sun 11/231:16 pmFSD - BTR
1 stop6h 10mAmerican Airlines
Deal found 10/30$344
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:10 pmMEM - FSD
2 stops8h 59mDelta
Tue 11/1810:58 amFSD - MEM
2 stops12h 06mDelta
Deal found 10/30$349
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:32 pmGPT - FSD
1 stop6h 45mAmerican Airlines
Sun 12/211:16 pmFSD - GPT
1 stop5h 40mAmerican Airlines
Deal found 10/30$379
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:16 amMEM - FSD
1 stop6h 57mAmerican Airlines
Wed 11/267:16 pmFSD - MEM
1 stop4h 43mAmerican Airlines
Deal found 10/29$387
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1310:35 amMOB - FSD
1 stop6h 06mAmerican Airlines
Sun 11/165:11 pmFSD - MOB
1 stop5h 39mAmerican Airlines
Deal found 10/29$419
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/229:16 pmMEM - FSD
1 stop13h 40mMultiple Airlines
Wed 11/2610:05 amFSD - MEM
2 stops24h 25mMultiple Airlines
Deal found 10/29$445
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:51 pmGPT - FSD
1 stop14h 36mMultiple Airlines
Mon 12/2210:02 amFSD - GPT
2 stops23h 23mMultiple Airlines
Deal found 10/30$455
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:55 pmMOB - FSD
1 stop6h 11mAmerican Airlines
Sun 12/285:16 pmFSD - MOB
1 stop5h 28mAmerican Airlines
Deal found 10/30$479
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:32 pmGPT - FSD
1 stop6h 45mAmerican Airlines
Mon 12/221:16 pmFSD - GPT
1 stop5h 40mAmerican Airlines
Deal found 10/30$499
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:02 amGPT - FSD
1 stop7h 26mAmerican Airlines
Mon 12/2210:46 amFSD - GPT
2 stops13h 26mAmerican Airlines
Deal found 10/30$513

Cheap flight deals from Mississippi to Sioux Falls

Keep the following information in mind while searching for Mississippi to Sioux Falls flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$279
(Delta)

One-way from

$175
(Trip.com)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
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From Mississippi to Sioux Falls Joe Foss Field
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One-way flight from Mississippi to Sioux Falls Joe Foss Field
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mississippi to Sioux Falls that are best for you.

Fly from

Mississippi

Fly to

Sioux Falls

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Wed 11/12

6:40 pm-11:00 pm

1 stop4h 20m

Sioux Falls Joe Foss Field

Mon 11/17

4:19 pm-10:33 pm

1 stop6h 14m

$279

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 11/14

4:33 pm-11:09 pm

1 stop6h 36m

Sioux Falls Joe Foss Field

Tue 11/18

1:30 pm-6:00 pm

1 stop4h 30m

$279

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 11/20

6:16 am-1:13 pm

1 stop6h 57m

Sioux Falls Joe Foss Field

Tue 11/25

7:16 pm-11:59 pm

1 stop4h 43m

$294

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sat 2/21

6:00 am-12:35 pm

1 stop6h 35m

Sioux Falls Joe Foss Field

Tue 2/24

5:15 am-11:23 am

1 stop6h 08m

$304

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Mon 11/17

4:25 pm-9:10 pm

1 stop4h 45m

Sioux Falls Joe Foss Field

Sun 11/23

1:16 pm-7:26 pm

1 stop6h 10m

$344

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Sat 2/21

5:00 am-12:37 pm

1 stop7h 37m

Sioux Falls Joe Foss Field

Tue 2/24

12:19 pm-11:49 pm

2 stops11h 30m

$366

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Thu 12/18

2:32 pm-9:17 pm

1 stop6h 45m

Sioux Falls Joe Foss Field

Sun 12/21

1:16 pm-6:56 pm

1 stop5h 40m

$379

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Sat 2/21

5:55 am-3:33 pm

2 stops9h 38m

Sioux Falls Joe Foss Field

Tue 2/24

1:20 pm-10:59 pm

2 stops9h 39m

$393

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Thu 11/13

10:35 am-4:41 pm

1 stop6h 06m

Sioux Falls Joe Foss Field

Sun 11/16

5:11 pm-10:50 pm

1 stop5h 39m

$419

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Sat 2/21

5:22 am-12:37 pm

1 stop7h 15m

Sioux Falls Joe Foss Field

Tue 2/24

5:31 pm-11:05 pm

1 stop5h 34m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 36 results
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Best time to book a flight from Mississippi to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Sioux Falls
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Sioux Falls from Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Sioux Falls from Mississippi.

  • How long is the flight from Mississippi to Sioux Falls?

    There are many flights that can get you from Mississippi to Sioux Falls in 4h 20m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Mississippi and Sioux Falls is about 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Mississippi to Sioux Falls one-way?

    $175 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $190 and $219, respectively.

  • What are the most popular routes from Mississippi to Sioux Falls?

    When deciding which route to take from Mississippi to Sioux Falls consider Mobile - Sioux Falls Joe Foss Field, Memphis - Sioux Falls Joe Foss Field or Gulfport Biloxi Regional - Sioux Falls Joe Foss Field as they are the most popular.

  • Can I find deals for flights from Mississippi to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Mississippi to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Sioux Falls.

  • Can I find deals for business class flights from Mississippi to Sioux Falls?

    Yes. Cheapflights offers flight deals from Mississippi to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Top airline flying from Mississippi to Sioux Falls

Discover the top airline that operate flights from Mississippi to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$451FlexibilityNo cancel feeOn-time71%

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