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Sioux Falls

$237+ Cheap flights from Mississippi to Sioux Falls (FSD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Sep 8 — Sep 151
Mon 9/8
Mon 9/15
1 adult, Economy
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Cheap flight deals from Mississippi to Sioux Falls

Keep the following information in mind while searching for Mississippi to Sioux Falls flight deals. Data was last updated September 3, 2025.

Round-trip from

$259
(American Airlines)

One-way from

$237
(Delta)
From Mississippi to Sioux Falls Joe Foss Field
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One-way flight from Mississippi to Sioux Falls Joe Foss Field
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Find flight deals from Mississippi to Sioux Falls

Cheapest flights from Mississippi to Sioux Falls
Explore the most affordable flight options available from Mississippi to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2025.

This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/192:15 pmBTR - FSD
1 stop6h 55mAmerican Airlines
Sun 11/231:16 pmFSD - BTR
1 stop6h 10mAmerican Airlines
Deal found 9/3$259
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:25 pmMEM - FSD
1 stop4h 56mUnited Airlines
Mon 9/293:12 pmFSD - MEM
1 stop6h 36mUnited Airlines
Deal found 9/2$274
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:52 pmMEM - FSD
1 stop5h 10mDelta
Sun 9/215:30 amFSD - MEM
1 stop4h 48mDelta
Deal found 9/2$279
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/175:30 amBTR - FSD
1 stop7h 08mAmerican Airlines
Sat 9/205:33 pmFSD - BTR
1 stop5h 38mAmerican Airlines
Deal found 9/3$289
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:52 pmMEM - FSD
1 stop5h 10mDelta
Sun 9/215:30 amFSD - MEM
1 stop7h 44mDelta
Deal found 9/1$304
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:15 pmBTR - FSD
1 stop6h 55mAmerican Airlines
Wed 11/195:30 amFSD - BTR
2 stops8h 20mAmerican Airlines
Deal found 9/3$309
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/59:37 amMEM - FSD
1 stop7h 26mAmerican Airlines
Mon 9/85:19 pmFSD - MEM
1 stop5h 38mAmerican Airlines
Deal found 9/1$333
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/512:20 pmMEM - FSD
1 stop5h 04mDelta
Mon 9/812:56 pmFSD - MEM
2 stops10h 08mDelta
Deal found 9/1$338
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1712:05 pmBTR - FSD
2 stops10h 07mUnited Airlines
Sat 9/203:12 pmFSD - BTR
2 stops8h 12mUnited Airlines
Deal found 9/3$359
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:25 amMEM - FSD
1 stop7h 13mAmerican Airlines
Mon 9/2912:18 pmFSD - MEM
2 stops10h 41mAmerican Airlines
Deal found 9/2$382
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/285:25 amMEM - FSD
1 stop7h 14mAmerican Airlines
Sat 10/41:19 pmFSD - MEM
1 stop4h 47mAmerican Airlines
Deal found 9/1$397
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/184:32 pmBTR - FSD
1 stop4h 47mAmerican Airlines
Mon 9/221:19 pmFSD - BTR
1 stop4h 44mAmerican Airlines
Deal found 9/3$416

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 3, 2025.
Use the filters below to find and compare flights from Mississippi to Sioux Falls that are best for you.

Fly from

Mississippi

Fly to

Sioux Falls

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sat 2/21

6:00 am-12:35 pm

1 stop6h 35m

Sioux Falls Joe Foss Field

Tue 2/24

5:15 am-11:23 am

1 stop6h 08m

$249

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Wed 11/19

2:15 pm-9:10 pm

1 stop6h 55m

Sioux Falls Joe Foss Field

Sun 11/23

1:16 pm-7:26 pm

1 stop6h 10m

$259

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Fri 9/26

3:25 pm-8:21 pm

1 stop4h 56m

Sioux Falls Joe Foss Field

Mon 9/29

3:12 pm-9:48 pm

1 stop6h 36m

$274

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Wed 9/17

5:52 pm-11:02 pm

1 stop5h 10m

Sioux Falls Joe Foss Field

Sun 9/21

5:30 am-10:18 am

1 stop4h 48m

$279

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Wed 9/17

5:30 am-12:38 pm

1 stop7h 08m

Sioux Falls Joe Foss Field

Sat 9/20

5:33 pm-11:11 pm

1 stop5h 38m

$289

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 9/18

5:52 pm-11:02 pm

1 stop5h 10m

Sioux Falls Joe Foss Field

Sun 9/21

5:30 am-1:14 pm

1 stop7h 44m

$304

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Fri 11/14

2:15 pm-9:10 pm

1 stop6h 55m

Sioux Falls Joe Foss Field

Wed 11/19

10:59 am-8:50 pm

2 stops9h 51m

$309

Baton RougeSioux Falls

BTR - FSD

BTRFSD

Baton Rouge Ryan

Wed 9/17

12:05 pm-10:12 pm

2 stops10h 07m

Sioux Falls Joe Foss Field

Sat 9/20

3:12 pm-11:24 pm

2 stops8h 12m

$359

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Sat 2/21

2:15 pm-10:58 pm

2 stops8h 43m

Sioux Falls Joe Foss Field

Tue 2/24

1:20 pm-10:09 pm

2 stops8h 49m

$369

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Sat 2/21

5:55 am-3:33 pm

2 stops9h 38m

Sioux Falls Joe Foss Field

Tue 2/24

1:20 pm-10:59 pm

2 stops9h 39m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/3

Showing 1-10 of 18 results
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Best time to book a flight from Mississippi to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Sioux Falls
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Sioux Falls from Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Sioux Falls from Mississippi.

  • How long is the flight from Mississippi to Sioux Falls?

    There are many flights that can get you from Mississippi to Sioux Falls in 4h 56m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Mississippi and Sioux Falls is about 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Mississippi to Sioux Falls?

    When deciding which route to take from Mississippi to Sioux Falls consider Memphis - Sioux Falls Joe Foss Field, Mobile - Sioux Falls Joe Foss Field or Baton Rouge Ryan - Sioux Falls Joe Foss Field as they are the most popular.

  • Can I find deals for flights from Mississippi to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Mississippi to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Sioux Falls.

  • Can I find deals for business class flights from Mississippi to Sioux Falls?

    Yes. Cheapflights offers flight deals from Mississippi to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Sioux Falls?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Sioux Falls (average of $334). Flying from Mississippi to Sioux Falls in December is currently the most expensive (average of $446). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Mississippi to Sioux Falls

Discover the top airline that operate flights from Mississippi to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$288Average$582FlexibilityNo cancel feeOn-time71%

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