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Sioux Falls

$269+ Cheap flights from Mississippi to Sioux Falls (FSD)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — FSD
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Mississippi to Sioux Falls

Cheapest flights from Mississippi to Sioux Falls
Explore the most affordable flight options available from Mississippi to Sioux Falls. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/196:00 am
MEM
-
FSD
1 stop4h 08m
Delta
Sun 2/224:19 pm
FSD
-
MEM
1 stop6h 05m
Delta
Deal found 1/27$269
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:25 am
GPT
-
FSD
1 stop5h 27m
American Airlines
Tue 7/76:27 am
FSD
-
GPT
1 stop7h 21m
American Airlines
Deal found 1/27$329
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:30 am
MEM
-
FSD
1 stop14h 27m
United Airlines
Mon 2/236:45 pm
FSD
-
MEM
1 stop27h 14m
United Airlines
Deal found 1/27$372
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/18:09 pm
MEM
-
FSD
1 stop17h 48m
Multiple Airlines
Sat 3/711:59 am
FSD
-
MEM
2 stops26h 43m
Multiple Airlines
Deal found 1/26$380
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MEM
-
FSD
1 stop4h 08m
Delta
Sun 3/11:00 pm
FSD
-
MEM
2 stops8h 27m
Delta
Deal found 1/26$399
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:12 am
MOB
-
FSD
1 stop5h 40m
American Airlines
Wed 7/225:34 pm
FSD
-
MOB
1 stop6h 18m
American Airlines
Deal found 1/27$403
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:01 am
MEM
-
FSD
1 stop4h 41m
American Airlines
Sat 3/75:19 pm
FSD
-
MEM
1 stop5h 44m
American Airlines
Deal found 1/28$410
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:08 am
MEM
-
FSD
1 stop6h 34m
American Airlines
Sun 3/12:08 pm
FSD
-
MEM
2 stops9h 43m
American Airlines
Deal found 1/27$412
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:06 pm
BTR
-
FSD
2 stops9h 41m
United Airlines
Sat 10/319:14 am
FSD
-
BTR
2 stops13h 32m
United Airlines
Deal found 1/27$432
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:53 am
MEM
-
FSD
2 stops10h 17m
American Airlines
Sun 2/222:08 pm
FSD
-
MEM
2 stops9h 43m
American Airlines
Deal found 1/27$435
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/277:00 am
MOB
-
FSD
2 stops10h 18m
United Airlines
Sat 1/316:00 am
FSD
-
MOB
2 stops10h 09m
United Airlines
Deal found 1/26$620
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:55 am
GPT
-
FSD
2 stops9h 52m
United Airlines
Sat 10/315:00 pm
FSD
-
GPT
2 stops21h 26m
United Airlines
Deal found 1/27$634

Find flight deals from Mississippi to Sioux Falls

Keep the following information in mind while searching for Mississippi to Sioux Falls flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)
Provider with most accurate pricing for Jackson-Evers Intl-Sioux Falls Joe Foss Field flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jackson-Evers Intl-Sioux Falls Joe Foss Field flights.
Search Deals
From Mississippi to Sioux Falls Joe Foss Field
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Sioux Falls that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Mississippi to Sioux Falls that are best for you.

Fly from

Mississippi

Fly to

Sioux Falls

Route

Depart

Return

Price

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/19

6:00 am-10:08 am

1 stop4h 08m

Sioux Falls Joe Foss Field

Sun 2/22

4:19 pm-10:24 pm

1 stop6h 05m

$269

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/26

7:01 am-11:42 am

1 stop4h 41m

Sioux Falls Joe Foss Field

Sun 3/1

2:08 pm-9:26 pm

1 stop7h 18m

$269

GulfportSioux Falls

GPT - FSD

GPTFSD

Gulfport Biloxi Regional

Tue 6/30

11:25 am-4:52 pm

1 stop5h 27m

Sioux Falls Joe Foss Field

Tue 7/7

6:27 am-1:48 pm

1 stop7h 21m

$329

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/19

7:30 am-9:57 pm

1 stop14h 27m

Sioux Falls Joe Foss Field

Mon 2/23

6:45 pm-9:59 pm

1 stop27h 14m

$372

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sun 3/1

8:09 pm-1:57 pm

1 stop17h 48m

Sioux Falls Joe Foss Field

Sat 3/7

11:59 am-2:42 pm

2 stops26h 43m

$394

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Thu 2/26

6:00 am-10:08 am

1 stop4h 08m

Sioux Falls Joe Foss Field

Sun 3/1

1:00 pm-9:27 pm

2 stops8h 27m

$399

MemphisSioux Falls

MEM - FSD

MEMFSD

Memphis

Sun 3/1

7:01 am-11:42 am

1 stop4h 41m

Sioux Falls Joe Foss Field

Sat 3/7

5:19 pm-11:03 pm

1 stop5h 44m

$410

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Thu 7/16

11:12 am-4:52 pm

1 stop5h 40m

Sioux Falls Joe Foss Field

Wed 7/22

6:27 am-9:34 pm

2 stops15h 07m

$610

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Thu 7/16

9:30 am-9:47 pm

2 stops36h 17m

Sioux Falls Joe Foss Field

Wed 7/22

6:20 pm-11:36 am

2 stops17h 16m

$732

MobileSioux Falls

MOB - FSD

MOBFSD

Mobile

Wed 5/13

5:22 am-1:01 pm

1 stop7h 39m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 15 results
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Best time to book a flight from Mississippi to Sioux Falls

Have a flexible travel schedule? Discover the best time to fly to Sioux Falls from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Sioux Falls
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Sioux Falls. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Sioux Falls from Mississippi?

    Located just 2.6 mi from the city center, Sioux Falls Joe Foss Field (FSD) is the airport most travelers will use when flying to Sioux Falls from Mississippi.

  • How long is the flight from Mississippi to Sioux Falls?

    There are many flights that can get you from Mississippi to Sioux Falls in 4h 08m. Fly via Delta, American Airlines, or United Airlines to get the fastest option. The distance between Mississippi and Sioux Falls is about 691 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Mississippi to Sioux Falls?

    When deciding which route to take from Mississippi to Sioux Falls consider Memphis - Sioux Falls Joe Foss Field, Mobile - Sioux Falls Joe Foss Field or Baton Rouge Ryan - Sioux Falls Joe Foss Field as they are the most popular.

  • Can I find deals for flights from Mississippi to Sioux Falls that include hotel bookings?

    Yes. In addition to deals on Mississippi to Sioux Falls flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Sioux Falls?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Sioux Falls.

  • Can I find deals for business class flights from Mississippi to Sioux Falls?

    Yes. Cheapflights offers flight deals from Mississippi to Sioux Falls by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sioux Falls?

Book flights to Sioux Falls if you plan to visit one of these locations
Marshall

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Alternative routes for Mississippi to Sioux Falls

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Mississippi to Sioux Falls

Discover the top airline that operate flights from Mississippi to Sioux Falls. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$451FlexibilityNo cancel feeOn-time71%

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