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Sao Paulo

$975+ Cheap flights from Knoxville (TYS) to Sao Paulo, Brazil (SAO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAO
Jul 14 — Jul 211
Tue 7/14
Tue 7/21
1 adult, Economy
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Cheap flight deals from Knoxville to Sao Paulo

Cheapest flights from Knoxville to Sao Paulo
Explore the most affordable flight options available from Knoxville to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:29 am
TYS
-
GRU
2 stops25h 46m
Multiple Airlines
Sun 9/278:30 am
GRU
-
TYS
1 stop33h 13m
Multiple Airlines
Deal found 6/11$975
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:11 pm
TYS
-
GRU
2 stops21h 04m
LATAM Airlines
Sun 9/277:15 pm
GRU
-
TYS
2 stops16h 50m
LATAM Airlines
Deal found 6/11$1,063
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:40 am
TYS
-
GRU
1 stop23h 00m
Delta
Mon 8/38:30 pm
GRU
-
TYS
2 stops20h 00m
Delta
Deal found 6/11$1,073
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:00 am
TYS
-
GRU
1 stop22h 15m
United Airlines
Sun 12/69:30 pm
GRU
-
TYS
1 stop14h 29m
United Airlines
Deal found 6/9$1,083
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:55 pm
TYS
-
GRU
1 stop11h 45m
LATAM Airlines
Sun 12/611:45 pm
GRU
-
TYS
1 stop19h 33m
LATAM Airlines
Deal found 6/11$1,093
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:30 am
TYS
-
GRU
1 stop34h 10m
Multiple Airlines
Sat 10/105:15 pm
GRU
-
TYS
2 stops28h 34m
Multiple Airlines
Deal found 6/9$1,106
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:45 am
TYS
-
GRU
1 stop26h 45m
United Airlines
Tue 7/289:50 pm
GRU
-
TYS
2 stops23h 54m
United Airlines
Deal found 6/13$1,126
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:34 pm
TYS
-
GRU
1 stop15h 56m
United Airlines
Sun 9/279:50 pm
GRU
-
TYS
1 stop21h 15m
United Airlines
Deal found 6/12$1,133
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:26 am
TYS
-
GRU
2 stops18h 04m
LATAM Airlines
Fri 7/1711:45 pm
GRU
-
TYS
2 stops34h 51m
LATAM Airlines
Deal found 6/11$1,154
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:45 pm
TYS
-
GRU
2 stops38h 45m
United Airlines
Mon 8/310:20 pm
GRU
-
TYS
2 stops26h 34m
United Airlines
Deal found 6/11$1,155

Find flight deals from Knoxville to Sao Paulo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$975
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo (SAO) flights.
Search Deals
From Knoxville McGhee Tyson to Sao Paulo (SAO)
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 9/22

10:29 am-1:15 pm

2 stops25h 46m

Sao Paulo Guarulhos Intl

Sun 9/27

8:30 am-4:43 pm

1 stop33h 13m

$975

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 9/22

6:11 pm-4:15 pm

2 stops21h 04m

Sao Paulo Guarulhos Intl

Sun 9/27

7:15 pm-11:05 am

2 stops16h 50m

$1,063

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 7/27

5:40 am-5:40 am

1 stop23h 00m

Sao Paulo Guarulhos Intl

Mon 8/3

8:30 pm-3:30 pm

2 stops20h 00m

$1,073

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 12/2

7:00 am-7:15 am

1 stop22h 15m

Sao Paulo Guarulhos Intl

Sun 12/6

9:30 pm-9:59 am

1 stop14h 29m

$1,083

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 9/22

1:34 pm-6:30 am

1 stop15h 56m

Sao Paulo Guarulhos Intl

Sun 9/27

9:50 pm-6:05 pm

1 stop21h 15m

$1,083
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 12/2

5:57 pm-9:35 am

1 stop13h 38m

Sao Paulo Guarulhos Intl

Sun 12/6

9:30 pm-11:06 am

1 stop15h 36m

$1,083

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Tue 9/22

2:00 pm-7:15 am

2 stops16h 15m

Sao Paulo Guarulhos Intl

Sun 9/27

11:15 pm-3:35 pm

2 stops17h 20m

$1,087

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sat 10/3

9:30 am-8:40 pm

1 stop34h 10m

Sao Paulo Guarulhos Intl

Sat 10/10

5:15 pm-8:49 pm

2 stops28h 34m

$1,106

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Knoxville-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sao Paulo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sao Paulo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Sao Paulo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Sao Paulo. You should not have trouble finding flights to Sao Paulo from McGhee Tyson; the airport handles an average of 0 outbound flights to Sao Paulo per day. You should also have plenty of airline options to choose from since 0 airlines have flights from the Knoxville airport to Sao Paulo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Sao Paulo?

    For as low as $1,063, LATAM Airlines can have you in Sao Paulo from Knoxville in 21h 04m. There are 4768 mi between Knoxville and Sao Paulo. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sao Paulo.

  • Can I find deals for business class flights from Knoxville to Sao Paulo?

    Yes. Cheapflights offers flight deals from Knoxville to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos

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