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Sao Paulo

$771+ Cheap flights from Knoxville (TYS) to Sao Paulo, Brazil (SAO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAO
Jun 7 — Jun 141
Sun 6/7
Sun 6/14
1 adult, Economy
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Cheap flight deals from Knoxville to Sao Paulo

Cheapest flights from Knoxville to Sao Paulo
Explore the most affordable flight options available from Knoxville to Sao Paulo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:03 pm
TYS
-
GRU
2 stops27h 47m
Multiple Airlines
Mon 6/2911:40 am
GRU
-
TYS
1 stop12h 54m
Multiple Airlines
Deal found 5/8$771
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:00 am
TYS
-
GRU
2 stops39h 10m
Multiple Airlines
Thu 6/1111:40 am
GRU
-
TYS
1 stop34h 33m
Multiple Airlines
Deal found 5/6$809
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/47:15 am
TYS
-
GRU
2 stops36h 35m
Multiple Airlines
Thu 6/1111:40 am
GRU
-
TYS
1 stop34h 33m
Multiple Airlines
Deal found 5/6$901
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 pm
TYS
-
GRU
2 stops30h 30m
Multiple Airlines
Wed 6/1011:40 am
GRU
-
TYS
1 stop28h 12m
Multiple Airlines
Deal found 5/6$927
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:15 am
TYS
-
GRU
1 stop22h 15m
United Airlines
Tue 9/2210:20 pm
GRU
-
TYS
1 stop23h 28m
United Airlines
Deal found 5/4$1,003
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:45 am
TYS
-
GRU
2 stops24h 25m
United Airlines
Mon 9/2810:20 pm
GRU
-
TYS
1 stop15h 58m
United Airlines
Deal found 5/5$1,008
This BusinessClass deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 am
TYS
-
GRU
2 stops15h 45m
GOL
Tue 7/288:55 am
GRU
-
TYS
2 stops16h 04m
GOL
Deal found 5/8$1,031
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:35 pm
TYS
-
GRU
1 stop18h 55m
United Airlines
Sun 6/79:50 pm
GRU
-
TYS
1 stop21h 17m
United Airlines
Deal found 5/3$1,033
This KAYAK deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:56 am
TYS
-
GRU
2 stops16h 34m
LATAM Airlines
Thu 6/117:30 am
GRU
-
TYS
2 stops17h 27m
LATAM Airlines
Deal found 5/6$1,045
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:22 pm
TYS
-
GRU
2 stops32h 03m
Multiple Airlines
Sun 5/318:50 am
GRU
-
TYS
1 stop15h 16m
Multiple Airlines
Deal found 5/6$1,047
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:20 pm
TYS
-
GRU
2 stops31h 30m
Multiple Airlines
Mon 5/2511:40 am
GRU
-
TYS
1 stop26h 52m
Multiple Airlines
Deal found 5/4$1,049

Find flight deals from Knoxville to Sao Paulo

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Sao Paulo (SAO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$809
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Sao Paulo (SAO) flights.
Search Deals
From Knoxville McGhee Tyson to Sao Paulo (SAO)
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 6/4

7:15 am-8:50 pm

2 stops36h 35m

Sao Paulo Guarulhos Intl

Thu 6/11

11:40 am-9:13 pm

1 stop34h 33m

$906

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 9/17

7:15 am-6:30 am

1 stop22h 15m

Sao Paulo Guarulhos Intl

Tue 9/22

10:20 pm-8:48 pm

1 stop23h 28m

$1,003
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 9/23

4:00 pm-5:40 am

1 stop12h 40m

Sao Paulo Guarulhos Intl

Mon 9/28

2:55 pm-9:11 am

2 stops19h 16m

$1,003

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 9/23

10:00 am-9:30 am

1 stop22h 30m

Sao Paulo Guarulhos Intl

Mon 9/28

10:20 pm-1:18 pm

1 stop15h 58m

$1,003

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 9/17

5:30 am-8:00 pm

2 stops13h 30m

Sao Paulo Guarulhos Intl

Tue 9/22

8:30 pm-5:27 pm

2 stops21h 57m

$1,008

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 6/3

1:35 pm-9:30 am

1 stop18h 55m

Sao Paulo Guarulhos Intl

Sun 6/7

9:50 pm-6:07 pm

1 stop21h 17m

$1,033

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 6/4

1:59 pm-8:40 am

2 stops17h 41m

Sao Paulo Guarulhos Intl

Wed 6/10

3:45 am-11:57 pm

2 stops21h 12m

$1,045

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 6/4

10:25 am-5:40 am

1 stop18h 15m

Sao Paulo Guarulhos Intl

Thu 6/11

10:50 pm-2:49 pm

1 stop16h 59m

$1,053

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 6/22

7:19 pm-6:30 am

2 stops34h 11m

Sao Paulo Guarulhos Intl

Mon 6/29

9:50 pm-9:43 am

2 stops36h 53m

$1,058

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/7

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Knoxville-Sao Paulo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Sao Paulo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Sao Paulo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Sao Paulo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Sao Paulo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Sao Paulo

Have a flexible travel schedule? Discover the best time to fly to Sao Paulo from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Sao Paulo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Sao Paulo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Sao Paulo?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Sao Paulo. You should not have trouble finding flights to Sao Paulo from McGhee Tyson; the airport handles an average of 0 outbound flights to Sao Paulo per day. You should also have plenty of airline options to choose from since 0 airlines have flights from the Knoxville airport to Sao Paulo. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • How long is the flight from Knoxville to Sao Paulo?

    For as low as $1,003, United Airlines can have you in Sao Paulo from Knoxville in 12h 40m. There are 4768 mi between Knoxville and Sao Paulo. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Knoxville to Sao Paulo that include hotel bookings?

    Yes. In addition to deals on Knoxville to Sao Paulo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Sao Paulo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Sao Paulo.

  • Can I find deals for business class flights from Knoxville to Sao Paulo?

    Yes. Cheapflights offers flight deals from Knoxville to Sao Paulo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos

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