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Santo Domingo

$172+ Cheap flights from St. Louis (STL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDQ
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from St. Louis to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$472
(FlightHub)

One-way from

$172
(SmartFares)

Popular in

June

Cheapest in

September

Average price

$767
From Lambert-St Louis to Santo Domingo Las Americas
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One-way flight from Lambert-St Louis to Santo Domingo Las Americas
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Highest demand for flights based on searches. 11% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from St. Louis to Santo Domingo

Cheapest flights from St. Louis to Santo Domingo
Explore the most affordable flight options available from St. Louis to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:26 pmSTL - SDQ
1 stop15h 24mSpirit Airlines
Tue 8/510:55 amSDQ - STL
2 stops24h 34mSpirit Airlines
Deal found 6/11$472
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/263:34 pmSTL - SDQ
1 stop17h 16mMultiple Airlines
Sat 8/23:30 pmSDQ - STL
2 stops19h 22mMultiple Airlines
Deal found 6/11$482
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/296:00 amSTL - SDQ
2 stops13h 55mAmerican Airlines
Tue 8/57:00 amSDQ - STL
2 stops10h 47mAmerican Airlines
Deal found 6/11$519
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/262:36 pmSTL - SDQ
1 stop8h 43mFrontier
Sun 6/2911:49 amSDQ - STL
1 stop13h 04mFrontier
Deal found 6/11$555
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1710:48 amSTL - SDQ
2 stops12h 49mDelta
Fri 6/206:00 amSDQ - STL
2 stops13h 05mDelta
Deal found 6/11$679
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/285:30 pmSTL - SDQ
2 stops19h 40mUnited Airlines
Sat 7/53:20 pmSDQ - STL
2 stops32h 25mUnited Airlines
Deal found 6/10$772

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

St. Louis

Fly to

Santo Domingo

Route

Depart

Return

Price

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 7/29

5:26 pm-9:50 am

1 stop15h 24m

Santo Domingo Las Americas

Tue 8/5

10:55 am-10:29 am

2 stops24h 34m

$472

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sat 7/26

3:34 pm-9:50 am

1 stop17h 16m

Santo Domingo Las Americas

Sat 8/2

3:30 pm-9:52 am

2 stops19h 22m

$482

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 7/29

6:00 am-8:55 pm

2 stops13h 55m

Santo Domingo Las Americas

Tue 8/5

7:00 am-4:47 pm

2 stops10h 47m

$519

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Thu 6/26

2:36 pm-12:19 am

1 stop8h 43m

Santo Domingo Las Americas

Sun 6/29

11:49 am-11:53 pm

1 stop13h 04m

$555

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 6/17

10:48 am-12:37 am

2 stops12h 49m

Santo Domingo Las Americas

Fri 6/20

6:00 am-6:05 pm

2 stops13h 05m

$679

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sat 6/28

5:30 pm-2:10 pm

2 stops19h 40m

Santo Domingo Las Americas

Sat 7/5

3:20 pm-10:45 pm

2 stops32h 25m

$772

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sat 6/28

5:47 pm-10:44 am

1 stop15h 57m

$172

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 7/4

2:55 pm-2:39 pm

1 stop22h 44m

$180

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 7/4

6:36 pm-7:03 pm

3 stops23h 27m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from St. Louis to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santo Domingo

What is the cheapest month to book a flight from St. Louis to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $362). Flying from St. Louis to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SDQ?

Find hourly flight availability from St. Louis to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

It’s typically best to fly out from St. Louis to Santo Domingo at noon. Doing so could potentially save you 28% on the flight price compared to flying in the morning, which is usually more expensive.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated June 12, 2025.
To help decide which airline to fly from St. Louis to Santo Domingo, see what other customers have to say about Delta, United Airlines and American Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Spirit Airlines
6.3
Okay
8,052 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,295 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from St. Louis to Santo Domingo round-trip?

    Flying on Spirit Airlines is currently your cheapest option to Santo Domingo, with prices starting at $472. Additional round-trip tickets that might be worth considering are offered by American Airlines and Frontier, with the lowest prices starting at $519 and $555, respectively. Spirit Airlines is currently priced 23% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on St. Louis to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santo Domingo.

  • Can I find deals for business class flights from St. Louis to Santo Domingo?

    Yes. Cheapflights offers flight deals from St. Louis to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $362). Flying from St. Louis to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from St. Louis to Santo Domingo

Discover the top 3 airlines that operate flights from St. Louis to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$320Average$662FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$371Average$384FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$453Average$629FlexibilityNo cancel feeOn-time71%

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