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Santo Domingo

$178+ Cheap flights from St. Louis (STL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDQ
Apr 11 — Apr 181
Sat 4/11
Sat 4/18
1 adult, Economy
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Cheap flight deals from St. Louis to Santo Domingo

Cheapest flights from St. Louis to Santo Domingo
Explore the most affordable flight options available from St. Louis to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/274:51 pm
STL
-
SDQ
1 stop15h 50m
Frontier
Mon 4/63:01 pm
SDQ
-
STL
2 stops20h 29m
Frontier
Deal found 3/10$439
This Priceline deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/84:51 pm
STL
-
SDQ
1 stop15h 50m
Frontier
Sat 3/1410:56 am
SDQ
-
STL
1 stop21h 06m
Frontier
Deal found 3/7$489
This Priceline deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/314:44 pm
STL
-
SDQ
1 stop17h 13m
Frontier
Sat 6/610:15 am
SDQ
-
STL
1 stop14h 42m
Frontier
Deal found 3/9$495
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/308:12 pm
STL
-
SDQ
2 stops42h 16m
Frontier
Mon 4/133:01 pm
SDQ
-
STL
2 stops40h 49m
Frontier
Deal found 3/7$498
This CheapOair deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/64:59 pm
STL
-
SDQ
2 stops44h 54m
Frontier
Mon 4/133:01 pm
SDQ
-
STL
2 stops40h 49m
Frontier
Deal found 3/9$499
This CheapOair deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:12 pm
STL
-
SDQ
2 stops36h 34m
Frontier
Fri 4/1011:12 am
SDQ
-
STL
1 stop13h 46m
Frontier
Deal found 3/7$513
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:59 pm
STL
-
SDQ
1 stop20h 31m
Multiple Airlines
Fri 4/172:35 pm
SDQ
-
STL
2 stops17h 15m
Multiple Airlines
Deal found 3/11$546
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:24 am
STL
-
SDQ
1 stop8h 35m
American Airlines
Tue 4/286:00 am
SDQ
-
STL
2 stops11h 41m
American Airlines
Deal found 3/7$560
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:24 am
STL
-
SDQ
1 stop8h 35m
American Airlines
Thu 4/304:00 pm
SDQ
-
STL
1 stop7h 24m
American Airlines
Deal found 3/8$561
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:24 am
STL
-
SDQ
1 stop6h 54m
American Airlines
Fri 5/14:00 pm
SDQ
-
STL
1 stop7h 24m
American Airlines
Deal found 3/10$578

Find flight deals from St. Louis to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$439
(Kiwi.com)

One-way from

$178
(Trip.com)

Popular in

November

Cheapest in

September

Average price

$618
Provider with most accurate pricing for Lambert-St Louis-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Santo Domingo Las Americas flights.
Search Deals
From Lambert-St Louis to Santo Domingo Las Americas
Search Deals
One-way flight from Lambert-St Louis to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($64 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 3/30

8:12 pm-3:28 pm

2 stops42h 16m

Santo Domingo Las Americas

Mon 4/13

3:01 pm-6:50 am

2 stops40h 49m

$498

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 4/21

5:24 am-4:55 pm

1 stop10h 31m

Santo Domingo Las Americas

Tue 4/28

2:25 pm-10:24 pm

1 stop8h 59m

$560
Quickest round-trip

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Thu 4/23

5:24 am-2:59 pm

1 stop8h 35m

Santo Domingo Las Americas

Thu 4/30

4:00 pm-10:24 pm

1 stop7h 24m

$561

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 4/24

5:24 am-2:59 pm

1 stop8h 35m

Santo Domingo Las Americas

Fri 5/1

2:25 pm-11:46 pm

2 stops10h 21m

$578

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Thu 4/23

6:00 am-1:12 pm

1 stop6h 12m

Santo Domingo Las Americas

Thu 4/30

7:59 pm-10:34 am

2 stops15h 35m

$583

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Fri 4/10

6:00 am-1:12 pm

1 stop6h 12m

Santo Domingo Las Americas

Fri 4/17

2:37 pm-11:36 pm

1 stop9h 59m

$609

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sun 3/29

5:15 am-3:03 pm

1 stop8h 48m

Santo Domingo Las Americas

Sun 4/5

6:00 am-11:58 pm

1 stop18h 58m

$622

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 5/18

7:00 am-10:52 pm

2 stops14h 52m

Santo Domingo Las Americas

Mon 5/25

7:00 am-10:58 pm

1 stop16h 58m

$633

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sun 7/12

6:00 am-6:44 pm

2 stops11h 44m

Santo Domingo Las Americas

Fri 7/17

4:24 pm-10:53 pm

1 stop7h 29m

$643

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Thu 5/28

4:19 pm-10:57 am

1 stop17h 38m

Santo Domingo Las Americas

Fri 5/29

2:35 pm-12:21 am

2 stops10h 46m

$680

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from St. Louis to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santo Domingo in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santo Domingo

What is the cheapest month to book a flight from St. Louis to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $320). Flying from St. Louis to Santo Domingo in July is currently the most expensive (average of $675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated March 12, 2026.
Read through reviews of airlines operating flights from St. Louis to Santo Domingo, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,286 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,435 reviews
Delta
7.9
Good
8,286 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Santo Domingo?

    There are many flights that can get you from St. Louis to Santo Domingo in 6h 12m. Fly via Frontier, American Airlines, or Delta to get the fastest option. There are 1873 mi between St. Louis and Santo Domingo. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from St. Louis to Santo Domingo round-trip?

    Flying on Delta is currently your cheapest option to Santo Domingo, with prices starting at $524. Another option worth looking into is American Airlines, starting at $538 round trip. Delta is currently priced 19% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on St. Louis to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santo Domingo.

  • Can I find deals for business class flights from St. Louis to Santo Domingo?

    Yes. Cheapflights offers flight deals from St. Louis to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $320). Flying from St. Louis to Santo Domingo in July is currently the most expensive (average of $675). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 2 airlines flying from St. Louis to Santo Domingo

Discover the top 2 airlines that operate flights from St. Louis to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$524Average$594FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$538Average$654FlexibilityNo cancel feeOn-time71%

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