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Santo Domingo

$163+ Cheap flights from St. Louis (STL) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SDQ
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from St. Louis to Santo Domingo

Cheapest flights from St. Louis to Santo Domingo
Explore the most affordable flight options available from St. Louis to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:42 amSTL - SDQ
2 stops33h 03mMultiple Airlines
Fri 12/1912:35 pmSDQ - STL
1 stop7h 38mMultiple Airlines
Deal found 10/28$391
This Gotogate deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:42 amSTL - SDQ
2 stops21h 00mFrontier
Fri 12/198:42 pmSDQ - STL
2 stops27h 51mFrontier
Deal found 10/28$566
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:00 amSTL - SDQ
1 stop6h 42mDelta
Fri 11/143:57 pmSDQ - STL
1 stop9h 47mDelta
Deal found 10/27$568
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:15 amSTL - SDQ
1 stop9h 53mAmerican Airlines
Sat 12/64:58 pmSDQ - STL
1 stop9h 01mAmerican Airlines
Deal found 10/27$573
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amSTL - SDQ
1 stop6h 41mDelta
Fri 11/77:05 amSDQ - STL
1 stop11h 38mDelta
Deal found 10/26$576
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 pmSTL - SDQ
1 stop14h 07mAmerican Airlines
Mon 1/126:00 amSDQ - STL
1 stop13h 22mAmerican Airlines
Deal found 10/28$588
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:41 pmSTL - SDQ
1 stop22h 27mAmerican Airlines
Tue 11/251:25 pmSDQ - STL
1 stop11h 09mAmerican Airlines
Deal found 10/28$603

Cheap flight deals from St. Louis to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$391
(Kiwi.com)

One-way from

$163
(Kiwi.com)

Popular in

October

Cheapest in

February

Average price

$814
Provider with most accurate pricing for Lambert-St Louis-Santo Domingo Las Americas flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Santo Domingo Las Americas flights.
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From Lambert-St Louis to Santo Domingo Las Americas
Search Deals
One-way flight from Lambert-St Louis to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($17 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from St. Louis to Santo Domingo that are best for you.

Fly from

St. Louis

Fly to

Santo Domingo

Route

Depart

Return

Price

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 1/12

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Wed 1/21

3:46 pm-11:39 pm

1 stop9h 53m

$518

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 1/13

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Wed 1/21

3:46 pm-11:39 pm

1 stop9h 53m

$518

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 1/14

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Wed 1/21

3:46 pm-11:39 pm

1 stop9h 53m

$518

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 1/12

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Fri 1/23

8:45 pm-11:56 am

2 stops17h 11m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 1/14

12:00 pm-12:32 am

2 stops10h 32m

Santo Domingo Las Americas

Fri 1/23

7:31 am-8:45 pm

2 stops15h 14m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Sun 1/11

6:55 pm-1:08 pm

2 stops16h 13m

Santo Domingo Las Americas

Fri 1/23

7:31 am-8:45 pm

2 stops15h 14m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 1/13

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Thu 1/22

7:31 am-5:50 pm

2 stops12h 19m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Tue 1/13

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Fri 1/23

8:45 pm-4:39 pm

2 stops21h 54m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Wed 1/14

6:00 am-2:21 pm

1 stop6h 21m

Santo Domingo Las Americas

Thu 1/22

7:31 am-5:50 pm

2 stops12h 19m

$522

St. LouisSanto Domingo

STL - SDQ

STLSDQ

Lambert-St Louis

Mon 1/5

4:27 pm-3:32 am

1 stop9h 05m

$163

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 17 results
1
2

Compare providers for flights from St. Louis to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Santo Domingo in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Santo Domingo

What is the cheapest month to book a flight from St. Louis to Santo Domingo?

Currently, April is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $374). Flying from St. Louis to Santo Domingo in June is currently the most expensive (average of $610). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to SDQ?

Find hourly flight availability from St. Louis to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

It’s typically best to fly out from St. Louis to Santo Domingo at noon. Doing so could potentially save you 59% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 28, 2025.
Read through reviews of airlines operating flights from St. Louis to Santo Domingo, such as Delta, American Airlines, and Frontier. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,995 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Frontier
5.8
Fair
3,122 reviews
Delta
7.9
Good
7,995 reviews

Overall

7.9

Food

7.3

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Santo Domingo?

    There are many flights that can get you from St. Louis to Santo Domingo in 6h 21m. Fly via Delta to get the fastest option. There are 1873 mi between St. Louis and Santo Domingo.

  • What are the cheapest airlines flying from St. Louis to Santo Domingo round-trip?

    Flying on Frontier is currently your cheapest option to Santo Domingo, with prices starting at $371. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $514 and $529, respectively. Frontier is currently priced 43% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on St. Louis to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Santo Domingo.

  • Can I find deals for business class flights from St. Louis to Santo Domingo?

    Yes. Cheapflights offers flight deals from St. Louis to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Santo Domingo?

    Currently, April is the cheapest month in which you can book a flight from St. Louis to Santo Domingo (average of $374). Flying from St. Louis to Santo Domingo in June is currently the most expensive (average of $610). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 3 airlines flying from St. Louis to Santo Domingo

Discover the top 3 airlines that operate flights from St. Louis to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$371Average$384FlexibilityNo cancel feeOn-time62%
DeltaCheapest$514Average$596FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$529Average$644FlexibilityNo cancel feeOn-time71%

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