$126+ Cheap flights from South Carolina to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
Aug 5 — Aug 121
1 adult, Economy
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Find cheap flights from South Carolina to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Santo Domingo
Keep the following information in mind while searching for South Carolina to Santo Domingo flight deals. Data was last updated July 31, 2025.
Round-trip from | $290 (Booking.com) |
|---|---|
One-way from | $126 (Booking.com) |
Popular in | December |
Cheapest in | February |
Find flight deals from South Carolina to Santo Domingo
Cheapest flights from South Carolina to Santo DomingoExplore the most affordable flight options available from South Carolina to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.
Explore the most affordable flight options available from South Carolina to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.
This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/309:10 amCLT - SDQ
1 stop6h 50mSpirit Airlines
Wed 9/35:05 pmSDQ - CLT
1 stop16h 17mSpirit Airlines
Deal found 7/29![Spirit Airlines logo]()
$275
This CheapOair deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/79:09 pmCLT - SDQ
1 stop12h 00mMultiple Airlines
Thu 8/145:05 pmSDQ - CLT
1 stop6h 50mMultiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$315
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/318:19 pmCLT - SDQ
1 stop15h 58mFrontier
Tue 8/121:05 pmSDQ - CLT
1 stop20h 05mFrontier
Deal found 7/29![Frontier logo]()
$333
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:31 pmMYR - SDQ
2 stops21h 29mSpirit Airlines
Tue 8/195:05 pmSDQ - MYR
2 stops26h 40mSpirit Airlines
Deal found 7/30![Spirit Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/313:05 pmSAV - SDQ
1 stop25h 25mMultiple Airlines
Fri 9/55:05 pmSDQ - SAV
2 stops21h 10mMultiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$423
This Expedia deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/129:40 amCHS - SDQ
1 stop27h 44mJetBlue
Sat 10/258:10 amSDQ - CHS
1 stop9h 55mJetBlue
Deal found 7/31![JetBlue logo]()
$428
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/37:00 amCHS - SDQ
1 stop11h 00mDelta
Fri 9/52:47 pmSDQ - CHS
1 stop6h 37mDelta
Deal found 7/31![Delta logo]()
$441
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:36 pmCHS - SDQ
2 stops14h 49mAmerican Airlines
Sat 10/257:00 amSDQ - CHS
2 stops17h 05mAmerican Airlines
Deal found 7/31![American Airlines logo]()
$455
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/277:10 amSAV - SDQ
1 stop10h 50mDelta
Thu 9/112:50 pmSDQ - SAV
1 stop9h 05mDelta
Deal found 7/30![Delta logo]()
$465
This Expedia deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/279:56 amSAV - SDQ
1 stop10h 08mJetBlue
Tue 9/92:34 pmSDQ - SAV
2 stops25h 16mJetBlue
Deal found 7/31![JetBlue logo]()
$472
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/146:08 amGSP - SDQ
1 stop8h 02mUnited Airlines
Sun 9/211:10 pmSDQ - GSP
1 stop9h 50mUnited Airlines
Deal found 7/31![United Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/147:35 amGSP - SDQ
1 stop5h 49mDelta
Sun 9/216:03 amSDQ - GSP
2 stops15h 31mDelta
Deal found 7/31![Delta logo]()
$479
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from South Carolina to Santo Domingo that are best for you.
Fly from
South Carolina
Fly to
Santo Domingo
Route
Depart
Return
Price
CharlotteSanto Domingo
CLT - SDQ
CLTSDQ
Charlotte Douglas
Sat 8/30
9:10 am-4:00 pm
1 stop6h 50m
Santo Domingo Las Americas
Wed 9/3
5:05 pm-9:22 am
1 stop16h 17m
$275
CharlotteSanto Domingo
CLT - SDQ
CLTSDQ
Charlotte Douglas
Sun 8/10
8:19 pm-8:45 pm
1 stop24h 26m
Santo Domingo Las Americas
Sun 8/17
11:50 am-10:41 am
1 stop22h 51m
$333
CharlotteSanto Domingo
CLT - SDQ
CLTSDQ
Charlotte Douglas
Mon 8/18
10:56 pm-4:00 pm
2 stops17h 04m
Santo Domingo Las Americas
Wed 8/27
5:05 pm-9:16 am
1 stop16h 11m
$344
Myrtle BeachSanto Domingo
MYR - SDQ
MYRSDQ
Myrtle Beach Intl
Fri 8/15
6:31 pm-4:00 pm
2 stops21h 29m
Santo Domingo Las Americas
Tue 8/19
5:05 pm-7:45 pm
2 stops26h 40m
$357
SavannahSanto Domingo
SAV - SDQ
SAVSDQ
Savannah/Hilton Head
Sun 8/31
3:05 pm-4:30 pm
1 stop25h 25m
Santo Domingo Las Americas
Fri 9/5
5:05 pm-2:15 pm
2 stops21h 10m
$423
CharlestonSanto Domingo
CHS - SDQ
CHSSDQ
Charleston
Sun 10/12
9:40 am-1:24 pm
1 stop27h 44m
Santo Domingo Las Americas
Sat 10/25
8:10 am-6:05 pm
1 stop9h 55m
$428
CharlestonSanto Domingo
CHS - SDQ
CHSSDQ
Charleston
Wed 9/3
7:00 am-6:00 pm
1 stop11h 00m
Santo Domingo Las Americas
Fri 9/5
2:47 pm-9:24 pm
1 stop6h 37m
$441
CharlestonSanto Domingo
CHS - SDQ
CHSSDQ
Charleston
Sun 10/12
6:36 pm-9:25 am
2 stops14h 49m
Santo Domingo Las Americas
Sat 10/25
7:00 am-12:05 am
2 stops17h 05m
$455
SavannahSanto Domingo
SAV - SDQ
SAVSDQ
Savannah/Hilton Head
Wed 8/27
7:10 am-6:00 pm
1 stop10h 50m
Santo Domingo Las Americas
Thu 9/11
2:50 pm-11:55 pm
1 stop9h 05m
$465
SavannahSanto Domingo
SAV - SDQ
SAVSDQ
Savannah/Hilton Head
Wed 8/27
9:56 am-8:04 pm
1 stop10h 08m
Santo Domingo Las Americas
Tue 9/9
2:34 pm-3:50 pm
2 stops25h 16m
$472
Showing 1-10 of 34 results
Best time to book a flight from South Carolina to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Santo Domingo
What is the cheapest month to book a flight from South Carolina to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $362). Flying from South Carolina to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SDQ?
Find hourly flight availability from South Carolina to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.
When flying from South Carolina to Santo Domingo, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from South Carolina to Santo Domingo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Overall
8.0
Crew
8.5
Boarding
8.2
Entertainment
7.9
Comfort
7.9
Food
7.3
Reviews
1 / 20
10.0
ExcellentKim,May 2025
PIH - SLC
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Alternative routes for South Carolina to Santo Domingo
See prices for flight routes from nearby airports that may be better suited for you.
Top 3 airlines flying from South Carolina to Santo Domingo
Discover the top 3 airlines that operate flights from South Carolina to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$320 | Average$629 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$327 | Average$453 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$410 | Average$633 | FlexibilityNo cancel fee | On-time71% |