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Santo Domingo

$113+ Cheap flights from South Carolina to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDQ
dic. 3 — dic. 101
mié. 12/3
mié. 12/10
1 adult, Economy
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Find flight deals from South Carolina to Santo Domingo

Cheapest flights from South Carolina to Santo Domingo
Explore the most affordable flight options available from South Carolina to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 3, 2025.

This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/176:00 amCHS - SDQ
1 stop8h 06mUnited Airlines
jue. 11/204:18 pmSDQ - CHS
1 stop8h 24mUnited Airlines
Deal found 11/3$318
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/1712:51 pmCHS - SDQ
2 stops11h 45mDelta
jue. 11/206:45 amSDQ - CHS
2 stops11h 38mDelta
Deal found 11/3$322
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/23:42 pmCLT - SDQ
1 stop23h 47mMultiple Airlines
mar. 12/94:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$330
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/17:30 amCLT - SDQ
1 stop7h 00mSpirit Airlines
lun. 12/84:21 pmSDQ - CLT
1 stop8h 38mSpirit Airlines
Deal found 11/1$331
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/15:59 pmCLT - SDQ
1 stop20h 31mMultiple Airlines
lun. 12/810:19 amSDQ - CLT
1 stop27h 22mMultiple Airlines
Deal found 11/1$341
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/111:57 pmCLT - SDQ
1 stop6h 48mMultiple Airlines
lun. 12/154:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$343
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/128:54 amCLT - SDQ
1 stop25h 57mMultiple Airlines
mar. 12/164:21 pmSDQ - CLT
1 stop8h 38mMultiple Airlines
Deal found 11/2$345
This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/128:55 pmCLT - SDQ
2 stops13h 56mSpirit Airlines
mar. 12/164:21 pmSDQ - CLT
1 stop8h 38mSpirit Airlines
Deal found 11/2$357
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/127:59 pmCLT - SDQ
1 stop24h 46mMultiple Airlines
lun. 11/1710:19 amSDQ - CLT
1 stop12h 38mMultiple Airlines
Deal found 11/1$361
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/710:42 pmCLT - SDQ
1 stop22h 03mMultiple Airlines
vie. 11/1410:19 amSDQ - CLT
1 stop12h 38mMultiple Airlines
Deal found 11/2$365
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/27:30 amCLT - SDQ
1 stop7h 00mSpirit Airlines
mar. 12/94:21 pmSDQ - CLT
2 stops22h 41mSpirit Airlines
Deal found 11/2$368
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/111:57 pmCLT - SDQ
1 stop6h 48mMultiple Airlines
vie. 1/98:01 amSDQ - CLT
1 stop7h 47mMultiple Airlines
Deal found 11/1$370

Cheap flight deals from South Carolina to Santo Domingo

Keep the following information in mind while searching for South Carolina to Santo Domingo flight deals. Data was last updated noviembre 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(Cheapflightsfares)

One-way from

$113
(Cheapflightsfares)
Provider with most accurate pricing for Myrtle Beach Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santo Domingo Las Americas flights.
Search Deals
From South Carolina to Santo Domingo Las Americas
Search Deals
One-way flight from South Carolina to Santo Domingo Las Americas
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
Use the filters below to find and compare flights from South Carolina to Santo Domingo that are best for you.

Fly from

South Carolina

Fly to

Santo Domingo

Route

Depart

Return

Price

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

lun. 12/1

7:56 pm-12:15 pm

1 stop15h 19m

Santo Domingo Las Americas

vie. 12/12

4:58 pm-12:46 am

1 stop8h 48m

$318

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

lun. 11/17

6:00 am-3:06 pm

1 stop8h 06m

Santo Domingo Las Americas

jue. 11/20

4:18 pm-11:42 pm

1 stop8h 24m

$318

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

lun. 11/17

12:51 pm-1:36 am

2 stops11h 45m

Santo Domingo Las Americas

jue. 11/20

6:45 am-5:23 pm

2 stops11h 38m

$322

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

lun. 12/1

5:59 pm-3:30 pm

1 stop20h 31m

Santo Domingo Las Americas

lun. 12/8

10:19 am-12:41 pm

1 stop27h 22m

$341

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

mar. 1/6

9:38 pm-3:23 pm

1 stop16h 45m

Santo Domingo Las Americas

mié. 1/21

6:55 pm-12:59 am

1 stop7h 04m

$345

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

mié. 11/12

7:59 pm-9:45 pm

1 stop24h 46m

Santo Domingo Las Americas

lun. 11/17

4:25 pm-7:58 pm

2 stops28h 33m

$369

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

sáb. 1/24

5:45 am-1:39 am

2 stops18h 54m

Santo Domingo Las Americas

sáb. 1/31

6:55 pm-12:59 am

1 stop7h 04m

$376

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

dom. 12/28

9:34 pm-11:20 am

1 stop12h 46m

Santo Domingo Las Americas

mié. 12/31

3:59 am-9:39 am

1 stop6h 40m

$390

CharlotteSanto Domingo

CLT - SDQ

CLTSDQ

Charlotte Douglas

lun. 12/29

9:34 pm-11:20 am

1 stop12h 46m

Santo Domingo Las Americas

mié. 12/31

3:59 am-9:39 am

1 stop6h 40m

$401

CharlestonSanto Domingo

CHS - SDQ

CHSSDQ

Charleston

vie. 4/17

8:08 pm-10:50 am

1 stop14h 42m

Santo Domingo Las Americas

mié. 4/22

5:55 am-2:03 pm

2 stops8h 08m

$405

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santo Domingo

What is the cheapest month to book a flight from South Carolina to Santo Domingo?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $345). Flying from South Carolina to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDQ?

Find hourly flight availability from South Carolina to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 3, 2025.

When flying from South Carolina to Santo Domingo, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 59% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santo Domingo from South Carolina?

    If you book a flight to Santo Domingo from South Carolina, you will be flying to Las Americas, which is the city’s only airport. Santo Domingo Las Americas (SDQ) is located 17.5 mi from the center of Santo Domingo.

  • How long is the flight from South Carolina to Santo Domingo?

    For as low as $318, American Airlines can have you in Santo Domingo from South Carolina in 8h 06m. There are 1187 mi between South Carolina and Santo Domingo. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Santo Domingo one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $120. Users have also found prices from $147 and $147 on American Airlines and Delta, respectively.

  • What are the most popular routes from South Carolina to Santo Domingo?

    The most popular route from South Carolina to Santo Domingo is Charlotte Douglas - Santo Domingo Las Americas. You may also consider Charleston - Santo Domingo Las Americas or Greenville - Santo Domingo Las Americas.

  • Can I find deals for flights from South Carolina to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santo Domingo.

  • Can I find deals for business class flights from South Carolina to Santo Domingo?

    Yes. Cheapflights offers flight deals from South Carolina to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santo Domingo?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Santo Domingo (average of $345). Flying from South Carolina to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Alternative routes for South Carolina to Santo Domingo

See prices for flight routes from nearby airports that may be better suited for you.
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Orlando to Santiago de los Caballeros flights
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Dulles Intl to Santo Domingo flights
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George Bush Intcntl to Punta Cana flights
LaGuardia to Puerto Plata flights
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Miami to Santiago de los Caballeros flights
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Top 3 airlines flying from South Carolina to Santo Domingo

Discover the top 3 airlines that operate flights from South Carolina to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$327Average$453FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$338Average$542FlexibilityNo cancel feeOn-time71%
DeltaCheapest$420Average$641FlexibilityNo cancel feeOn-timeN/A

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