$674+ Cheap flights from Myrtle Beach (MYR) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SDQ
Nov 30 — Dec 71
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Santo Domingo
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Best
Last-minute
Cheapest flights from Myrtle Beach to Santo DomingoExplore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:10 am -
2 stops12h 09m
Sun 11/224:59 pm -
2 stops18h 23m
Deal found 10/28![American Airlines logo]()
$795
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 am -
2 stops10h 20m
Tue 11/107:00 am -
2 stops14h 57m
Deal found 10/27![American Airlines logo]()
$868
Best flights from Myrtle Beach to Santo DomingoDiscover carefully curated flight deals from Myrtle Beach to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
Discover carefully curated flight deals from Myrtle Beach to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 31, 2026.
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/206:12 am -
2 stops11h 12m
Sun 1/242:41 pm -
1 stop21h 04m
Deal found 10/30![American Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1811:27 am -
1 stop11h 19m
Mon 1/256:00 am -
1 stop12h 48m
Deal found 10/30![United Airlines logo]()
$887
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:10 am -
2 stops12h 09m
Sun 11/224:59 pm -
2 stops18h 23m
Deal found 10/26![American Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1611:27 am -
1 stop11h 19m
Fri 11/206:00 am -
1 stop29h 21m
Deal found 10/29![United Airlines logo]()
$953
Last-minute flights from Myrtle Beach to Santo DomingoDiscover last-minute flight deals from Myrtle Beach to Santo Domingo. Data last updated October 31, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Santo Domingo. Data last updated October 31, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 am -
2 stops10h 20m
Tue 11/107:00 am -
2 stops14h 57m
Deal found 10/27![American Airlines logo]()
$868
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:10 am -
2 stops12h 09m
Sun 11/224:59 pm -
2 stops18h 23m
Deal found 10/28![American Airlines logo]()
$795
Find flight deals from Myrtle Beach to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $630 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 31, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSanto Domingo
MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas
MYRSDQ
Myrtle Beach Intl
Wed 1/20
6:12 am-6:24 pm
2 stops11h 12m
Santo Domingo Las Americas
Sun 1/24
2:41 pm-10:45 am
1 stop21h 04m
$674
Myrtle BeachSanto Domingo
MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas
MYRSDQ
Myrtle Beach Intl
Fri 11/13
5:10 am-6:19 pm
2 stops12h 09m
Santo Domingo Las Americas
Sun 11/22
4:59 pm-10:22 am
2 stops18h 23m
$795
Quickest round-trip
Myrtle BeachSanto Domingo
MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas
MYRSDQ
Myrtle Beach Intl
Mon 1/18
11:27 am-11:46 pm
1 stop11h 19m
Santo Domingo Las Americas
Mon 1/25
6:00 am-5:48 pm
1 stop12h 48m
$887
Myrtle BeachSanto Domingo
MYR Myrtle Beach Intl - SDQ Santo Domingo Las Americas
MYRSDQ
Myrtle Beach Intl
Mon 11/16
11:27 am-11:46 pm
1 stop11h 19m
Santo Domingo Las Americas
Fri 11/20
6:00 am-10:21 am
1 stop29h 21m
$953
Sorted by cheapest first
Compare providers for flights from Myrtle Beach to Santo Domingo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santo Domingo in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Myrtle Beach with our price prediction graph.
MYR-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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