How long is the flight from Myrtle Beach to Santo Domingo?

A quick flight from Myrtle Beach to Santo Domingo can take about 18h 20m. Spirit Airlines provides one of the quickest options available for as low as $364. The distance between Myrtle Beach and Santo Domingo is about 1198 mi.

What is the cheapest airline to fly from Myrtle Beach to Santo Domingo round-trip?

Spirit Airlines, at $327, was found to be the cheapest airline from Myrtle Beach to Santo Domingo..

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What is the cheapest time of day to fly from MYR to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Myrtle Beach to Santo Domingo as you normally would.

Most accurate provider : When it comes to deals on Myrtle Beach-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santo Domingo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Myrtle Beach-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Myrtle Beach to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Myrtle Beach to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Myrtle Beach to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santo Domingo.

Can I find deals for business class flights from Myrtle Beach to Santo Domingo?

Yes. Cheapflights offers flight deals from Myrtle Beach to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$143+ Flights from Myrtle Beach to Santo Domingo

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Cheap flight deals from Myrtle Beach to Santo Domingo

Cheapest flights from Myrtle Beach to Santo Domingo
Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Mon 12/86:00 amMYR - SDQ

1 stop7h 42mDelta

Fri 12/123:57 pmSDQ - MYR

1 stop8h 46mDelta

Deal found 12/1

$518

Fri 12/269:54 amMYR - SDQ

1 stop16h 00mSpirit Airlines

Fri 1/23:59 amSDQ - MYR

1 stop15h 09mSpirit Airlines

Deal found 12/4

$801

Fri 12/192:14 pmMYR - SDQ

2 stops35h 40mMultiple Airlines

Mon 1/54:21 pmSDQ - MYR

1 stop26h 47mMultiple Airlines

Deal found 12/1

$803

Fri 12/199:54 amMYR - SDQ

1 stop16h 00mSpirit Airlines

Sun 1/43:59 amSDQ - MYR

1 stop15h 09mSpirit Airlines

Deal found 12/1

$804

Best flights from Myrtle Beach to Santo Domingo
Discover carefully curated flight deals from Myrtle Beach to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Mon 1/268:15 pmMYR - SDQ

1 stop18h 20mSpirit Airlines

Wed 2/44:40 pmSDQ - MYR

1 stop27h 40mSpirit Airlines

Deal found 12/3

$364

Mon 1/268:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$372

Mon 1/268:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Mon 2/29:34 pmSDQ - MYR

2 stops18h 08mMultiple Airlines

Deal found 12/3

$382

Thu 1/158:15 pmMYR - SDQ

1 stop18h 20mSpirit Airlines

Mon 1/194:40 pmSDQ - MYR

2 stops23h 02mSpirit Airlines

Deal found 12/3

$406

Tue 1/279:59 pmMYR - SDQ

1 stop17h 27mMultiple Airlines

Mon 2/29:34 pmSDQ - MYR

2 stops18h 08mMultiple Airlines

Deal found 12/3

$386

Sat 1/248:15 pmMYR - SDQ

2 stops12h 44mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$387

Thu 1/223:39 pmMYR - SDQ

1 stop8h 06mMultiple Airlines

Thu 1/294:40 pmSDQ - MYR

1 stop22h 33mMultiple Airlines

Deal found 12/3

$390

Sat 1/248:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Mon 2/26:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$392

Sun 2/18:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Tue 2/103:35 pmSDQ - MYR

2 stops24h 07mMultiple Airlines

Deal found 12/3

$395

Sun 1/258:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Sat 1/316:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$412

Fri 1/238:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Sat 1/316:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$412

Wed 1/2810:00 amMYR - SDQ

1 stop18h 25mMultiple Airlines

Mon 2/26:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$413

Last-minute flights from Myrtle Beach to Santo Domingo
Discover last-minute flight deals from Myrtle Beach to Santo Domingo. Data last updated December 4, 2025 and is based on user searches.

Thu 1/228:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$375

Fri 1/238:15 pmMYR - SDQ

1 stop18h 20mSpirit Airlines

Sun 2/14:40 pmSDQ - MYR

1 stop27h 40mSpirit Airlines

Deal found 12/3

$363

Fri 1/238:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Mon 2/29:34 pmSDQ - MYR

2 stops18h 08mMultiple Airlines

Deal found 12/3

$382

Sat 1/248:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$374

Sat 1/248:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Mon 2/29:34 pmSDQ - MYR

2 stops18h 08mMultiple Airlines

Deal found 12/3

$384

Sun 1/258:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Wed 1/286:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$373

Sun 1/258:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Mon 2/29:34 pmSDQ - MYR

2 stops18h 08mMultiple Airlines

Deal found 12/3

$383

Mon 1/268:15 pmMYR - SDQ

1 stop18h 20mSpirit Airlines

Wed 2/44:40 pmSDQ - MYR

1 stop27h 40mSpirit Airlines

Deal found 12/3

$364

Mon 1/268:15 pmMYR - SDQ

1 stop18h 20mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$372

Tue 1/2710:00 amMYR - SDQ

1 stop29h 26mMultiple Airlines

Sun 2/14:40 pmSDQ - MYR

1 stop27h 40mMultiple Airlines

Deal found 12/3

$350

Tue 1/2710:00 amMYR - SDQ

1 stop29h 26mMultiple Airlines

Wed 2/44:40 pmSDQ - MYR

1 stop27h 40mMultiple Airlines

Deal found 12/3

$351

Wed 1/2810:00 amMYR - SDQ

1 stop18h 25mMultiple Airlines

Wed 2/46:10 amSDQ - MYR

1 stop9h 32mMultiple Airlines

Deal found 12/3

$378

One-way flights from Myrtle Beach to Santo Domingo
Search for one-way flight options from Myrtle Beach to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Wed 12/249:54 amMYR - SDQ

1 stop16h 00mSpirit Airlines

Deal found 12/3

$143

Wed 12/245:11 amMYR - SDQ

3 stops9h 38mAmerican Airlines

Deal found 12/3

$1,239

Find flight deals from Myrtle Beach to Santo Domingo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$350 (Kiwi.com)
One-way from	$143 (FlightHub)

Provider with most accurate pricing for Myrtle Beach Intl-Santo Domingo Las Americas flight deals.

Search Deals

Provider most trusted by Cheapflights users for Myrtle Beach Intl-Santo Domingo Las Americas flights.

Search Deals

From Myrtle Beach Intl to Santo Domingo Las Americas

Search Deals

One-way flight from Myrtle Beach Intl to Santo Domingo Las Americas

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Mon 1/26

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Wed 2/4

4:40 pm-7:20 pm

1 stop27h 40m

$364

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Mon 1/26

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Wed 2/4

6:10 am-2:42 pm

1 stop9h 32m

$372

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Mon 1/26

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Mon 2/2

9:34 pm-2:42 pm

2 stops18h 08m

$382

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Tue 1/27

9:59 pm-4:26 pm

1 stop17h 27m

Santo Domingo Las Americas

Mon 2/2

9:34 pm-2:42 pm

2 stops18h 08m

$386

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 1/24

8:15 pm-9:59 am

2 stops12h 44m

Santo Domingo Las Americas

Wed 2/4

6:10 am-2:42 pm

1 stop9h 32m

$387

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Thu 1/22

3:39 pm-12:45 am

1 stop8h 06m

Santo Domingo Las Americas

Thu 1/29

4:40 pm-2:13 pm

1 stop22h 33m

$390

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sat 1/24

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Mon 2/2

6:10 am-2:42 pm

1 stop9h 32m

$392

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 2/1

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Tue 2/10

3:35 pm-2:42 pm

2 stops24h 07m

$395

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Thu 1/15

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Mon 1/19

4:40 pm-2:42 pm

2 stops23h 02m

$406

Myrtle BeachSanto Domingo

MYR - SDQ

MYRSDQ

Myrtle Beach Intl

Sun 1/25

8:15 pm-3:35 pm

1 stop18h 20m

Santo Domingo Las Americas

Sat 1/31

6:10 am-2:42 pm

1 stop9h 32m

$412

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 14 results

Compare providers for flights from Myrtle Beach to Santo Domingo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santo Domingo in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Santo Domingo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Myrtle Beach-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Myrtle Beach with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santo Domingo

What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Santo Domingo (average of $344). Flying from Myrtle Beach to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Spirit Airlines from Myrtle Beach to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Spirit Airlines

6.3

Okay

8,157 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Nov 2025

MCO - BWI

Sitting in exit seats without an upgrade should be allowed if nobody sitting in them what’s the big deal?

Spirit Airlines

6.3

Okay

8,157 reviews

Spirit Airlines

6.3

Okay

8,157 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Nov 2025

MCO - BWI

Sitting in exit seats without an upgrade should be allowed if nobody sitting in them what’s the big deal?

Related info for your journey

How long is the flight from Myrtle Beach to Santo Domingo?
A quick flight from Myrtle Beach to Santo Domingo can take about 18h 20m. Spirit Airlines provides one of the quickest options available for as low as $364. The distance between Myrtle Beach and Santo Domingo is about 1198 mi.
What is the cheapest airline to fly from Myrtle Beach to Santo Domingo round-trip?
Spirit Airlines, at $327, was found to be the cheapest airline from Myrtle Beach to Santo Domingo..
Can I find deals for flights from Myrtle Beach to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Myrtle Beach to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Myrtle Beach to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Santo Domingo.
Can I find deals for business class flights from Myrtle Beach to Santo Domingo?
Yes. Cheapflights offers flight deals from Myrtle Beach to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Santo Domingo (average of $344). Flying from Myrtle Beach to Santo Domingo in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top airline flying from Myrtle Beach to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$327	Average$453	FlexibilityNo cancel fee	On-time65%

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$143+ Cheap flights from Myrtle Beach (MYR) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/24. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Myrtle Beach to Santo Domingo with Cheapflights

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Cheap flight deals from Myrtle Beach to Santo Domingo

Cheapest flights from Myrtle Beach to Santo DomingoExplore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from Myrtle Beach to Santo Domingo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Myrtle Beach to Santo Domingo that are best for you.

Compare providers for flights from Myrtle Beach to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Santo Domingo in December.

Best time to book a flight from Myrtle Beach to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Myrtle Beach with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Santo Domingo

What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Peruse reviews from past customers who have flown with Spirit Airlines from Myrtle Beach to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Myrtle Beach to Santo Domingo?

What is the cheapest airline to fly from Myrtle Beach to Santo Domingo round-trip?

Can I find deals for flights from Myrtle Beach to Santo Domingo that include hotel bookings?

How can I find direct flights from Myrtle Beach to Santo Domingo?

Can I find deals for business class flights from Myrtle Beach to Santo Domingo?

What is the cheapest month to book a flight from Myrtle Beach to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Myrtle Beach to Santo Domingo

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Top airline flying from Myrtle Beach to Santo Domingo

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Cheapest flights from Myrtle Beach to Santo Domingo
Explore the most affordable flight options available from Myrtle Beach to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.