$398+ Cheap flights from Iowa to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SDQ
Nov 28 — Dec 51
1 adult, Economy
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Cheapest flights from Iowa to Santo DomingoExplore the most affordable flight options available from Iowa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.
Explore the most affordable flight options available from Iowa to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:56 pmDSM - SDQ
1 stop22h 27mMultiple Airlines
Thu 12/184:21 pmSDQ - DSM
1 stop8h 15mMultiple Airlines
Deal found 10/28![Multiple Airlines logo]()
$462
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:10 pmOMA - SDQ
2 stops16h 18mAmerican Airlines
Tue 12/91:28 pmSDQ - OMA
2 stops11h 02mAmerican Airlines
Deal found 10/28![American Airlines logo]()
$522
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:07 pmDSM - SDQ
2 stops18h 21mAmerican Airlines
Thu 12/1811:07 amSDQ - DSM
2 stops15h 30mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$531
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:00 amDSM - SDQ
1 stop15h 45mAmerican Airlines
Mon 11/244:45 pmSDQ - DSM
1 stop8h 53mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$553
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/106:19 amOMA - SDQ
2 stops17h 17mDelta
Fri 11/146:45 amSDQ - OMA
2 stops12h 27mDelta
Deal found 10/27![Delta logo]()
$572
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:00 amOMA - SDQ
2 stops15h 50mAmerican Airlines
Sat 12/134:58 pmSDQ - OMA
2 stops17h 39mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$577
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/128:00 amDSM - SDQ
3 stops29h 23mMultiple Airlines
Thu 12/183:59 amSDQ - DSM
2 stops13h 04mMultiple Airlines
Deal found 10/29![Multiple Airlines logo]()
$588
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:07 amOMA - SDQ
1 stop7h 35mDelta
Tue 12/93:57 pmSDQ - OMA
1 stop10h 19mDelta
Deal found 10/29![Delta logo]()
$588
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amOMA - SDQ
2 stops15h 45mAmerican Airlines
Sat 12/61:28 pmSDQ - OMA
2 stops11h 58mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$602
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:00 amOMA - SDQ
2 stops15h 45mAmerican Airlines
Sun 12/76:23 pmSDQ - OMA
2 stops18h 49mAmerican Airlines
Deal found 10/27![American Airlines logo]()
$607
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:42 pmOMA - SDQ
2 stops31h 17mMultiple Airlines
Tue 12/3012:35 pmSDQ - OMA
1 stop30h 07mMultiple Airlines
Deal found 10/27![Multiple Airlines logo]()
$643
Cheap flight deals from Iowa to Santo Domingo
Keep the following information in mind while searching for Iowa to Santo Domingo flight deals. Data was last updated October 29, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $462 (Kiwi.com) |
One-way from | $398 (American Airlines) |
Popular in | December |
Cheapest in | August |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Iowa to Santo Domingo that are best for you.
Fly from
Iowa
Fly to
Santo Domingo
Route
Depart
Return
Price
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Thu 12/11
2:56 pm-3:23 pm
1 stop22h 27m
Santo Domingo Las Americas
Thu 12/18
4:21 pm-10:36 pm
1 stop8h 15m
$462
OmahaSanto Domingo
OMA - SDQ
OMASDQ
Omaha Eppley Airfield
Sat 12/6
6:02 pm-12:28 pm
2 stops16h 26m
Santo Domingo Las Americas
Tue 12/9
1:28 pm-11:56 pm
1 stop12h 28m
$522
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Thu 12/11
4:07 pm-12:28 pm
2 stops18h 21m
Santo Domingo Las Americas
Thu 12/18
11:07 am-12:37 am
2 stops15h 30m
$531
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Mon 11/17
6:00 am-11:45 pm
1 stop15h 45m
Santo Domingo Las Americas
Mon 11/24
4:45 pm-11:38 pm
1 stop8h 53m
$553
OmahaSanto Domingo
OMA - SDQ
OMASDQ
Omaha Eppley Airfield
Mon 11/10
5:55 pm-1:23 pm
2 stops17h 28m
Santo Domingo Las Americas
Fri 11/14
3:57 pm-12:14 am
1 stop10h 17m
$572
OmahaSanto Domingo
OMA - SDQ
OMASDQ
Omaha Eppley Airfield
Mon 3/2
8:00 am-11:46 pm
2 stops13h 46m
Santo Domingo Las Americas
Fri 3/6
6:00 am-5:28 pm
2 stops13h 28m
$572
OmahaSanto Domingo
OMA - SDQ
OMASDQ
Omaha Eppley Airfield
Mon 3/2
7:00 am-11:59 pm
2 stops14h 59m
Santo Domingo Las Americas
Fri 3/6
11:02 am-10:52 pm
1 stop13h 50m
$572
OmahaSanto Domingo
OMA - SDQ
OMASDQ
Omaha Eppley Airfield
Sun 12/7
6:00 am-11:50 pm
2 stops15h 50m
Santo Domingo Las Americas
Sat 12/13
4:58 pm-8:37 am
2 stops17h 39m
$577
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Sat 11/29
5:26 pm-2:04 pm
2 stops18h 38m
Santo Domingo Las Americas
Sun 12/7
6:23 pm-10:28 am
2 stops18h 05m
$597
Des MoinesSanto Domingo
DSM - SDQ
DSMSDQ
Des Moines
Fri 12/12
7:28 pm-3:23 pm
2 stops17h 55m
Santo Domingo Las Americas
Fri 12/19
6:30 am-3:03 pm
1 stop10h 33m
$602
Showing 1-10 of 12 results
Best time to book a flight from Iowa to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Santo Domingo
What is the cheapest time of day to fly from IA to SDQ?
Find hourly flight availability from Iowa to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.
A simple way to save on the total cost of your ticket is to fly from Iowa to Santo Domingo in the evening. If you’re flexible enough to do this you can expect to save up to 52% on your trip compared to booking a flight at noon.
Related info for your journey
Find useful and relevant information for your journey from Iowa to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Alternative routes for Iowa to Santo Domingo
See prices for flight routes from nearby airports that may be better suited for you.
Top 2 airlines flying from Iowa to Santo Domingo
Discover the top 2 airlines that operate flights from Iowa to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$524 | Average$574 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$529 | Average$708 | FlexibilityNo cancel fee | On-time71% |