HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santo Domingo

$154+ Cheap flights from Denver (DEN) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SDQ
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in July or October, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:59 amDEN - SDQ
1 stop11h 15mMultiple Airlines
Sat 12/1312:49 pmSDQ - DEN
2 stops37h 10mMultiple Airlines
Deal found 11/16$358
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:15 pmDEN - SDQ
2 stops34h 10mMultiple Airlines
Wed 12/1010:19 amSDQ - DEN
1 stop25h 24mMultiple Airlines
Deal found 11/15$363
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:45 pmDEN - SDQ
2 stops39h 45mMultiple Airlines
Wed 12/1010:19 amSDQ - DEN
1 stop25h 24mMultiple Airlines
Deal found 11/15$387
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/234:49 pmDEN - SDQ
2 stops43h 41mMultiple Airlines
Wed 12/1010:19 amSDQ - DEN
1 stop25h 24mMultiple Airlines
Deal found 11/15$395
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:59 amDEN - SDQ
1 stop11h 20mFrontier
Tue 12/234:34 pmSDQ - DEN
2 stops43h 22mFrontier
Deal found 11/16$401
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3112:14 amDEN - SDQ
2 stops23h 40mMultiple Airlines
Sat 1/104:43 pmSDQ - DEN
1 stop22h 38mMultiple Airlines
Deal found 11/15$412
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1011:25 pmDEN - SDQ
1 stop19h 20mMultiple Airlines
Mon 12/154:21 pmSDQ - DEN
2 stops23h 11mMultiple Airlines
Deal found 11/17$416
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:14 pmDEN - SDQ
1 stop14h 15mMultiple Airlines
Thu 12/118:30 pmSDQ - DEN
2 stops29h 29mMultiple Airlines
Deal found 11/15$420
This Kiwi.com deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:14 pmDEN - SDQ
1 stop14h 15mMultiple Airlines
Sat 12/64:21 pmSDQ - DEN
2 stops19h 35mMultiple Airlines
Deal found 11/15$421

Cheap flight deals from Denver to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$322
(Kiwi.com)

One-way from

$154
(Trip.com)

Popular in

December

Cheapest in

July

Average price

$628
Provider with most accurate pricing for Denver Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Santo Domingo Las Americas flights.
Search Deals
From Denver Intl to Santo Domingo Las Americas
Search Deals
One-way flight from Denver Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Fly from

Denver

Fly to

Santo Domingo

Route

Depart

Return

Price

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 1/29

1:40 pm-4:34 am

1 stop11h 54m

Santo Domingo Las Americas

Fri 2/6

8:45 pm-10:45 am

1 stop17h 00m

$463

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 11/27

11:14 pm-4:29 pm

1 stop14h 15m

Santo Domingo Las Americas

Sat 12/6

3:35 pm-8:43 am

1 stop20h 08m

$488

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Tue 1/13

12:05 am-4:29 pm

2 stops13h 24m

Santo Domingo Las Americas

Wed 2/11

10:19 am-9:08 am

1 stop25h 49m

$504

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sun 11/23

8:00 pm-4:29 pm

2 stops17h 29m

Santo Domingo Las Americas

Tue 12/9

3:35 pm-8:43 am

1 stop20h 08m

$505

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 11/24

11:14 pm-9:45 pm

1 stop19h 31m

Santo Domingo Las Americas

Thu 12/11

10:26 am-11:04 pm

2 stops15h 38m

$524

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 12/25

11:59 pm-11:20 am

1 stop8h 21m

Santo Domingo Las Americas

Wed 12/31

8:20 am-8:55 am

2 stops27h 35m

$529

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 11/27

8:05 am-1:36 am

1 stop14h 31m

Santo Domingo Las Americas

Thu 12/4

3:57 pm-10:53 pm

1 stop9h 56m

$530

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sun 11/23

11:59 pm-1:23 pm

1 stop10h 24m

Santo Domingo Las Americas

Wed 12/10

8:43 pm-10:53 am

1 stop17h 10m

$530

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 11/26

12:20 pm-1:36 am

1 stop10h 16m

Santo Domingo Las Americas

Sun 12/7

3:57 pm-12:07 am

1 stop11h 10m

$530

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 11/26

7:10 am-1:36 am

1 stop15h 26m

Santo Domingo Las Americas

Tue 12/9

2:54 pm-11:45 pm

1 stop11h 51m

$530

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 17 results
1
2

Compare providers for flights from Denver to Santo Domingo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santo Domingo in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santo Domingo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Santo Domingo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santo Domingo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santo Domingo. Price data was last updated on November 14, 2025.

The price you pay for your flight from Denver to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santo Domingo?

Currently, October is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $253). Flying from Denver to Santo Domingo in August is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SDQ?

Find hourly flight availability from Denver to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

It’s optimal to fly from Denver to Santo Domingo in the afternoon. By choosing this option you can save up to 32% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated November 17, 2025.
See what other customers who have flown with Delta, Copa Airlines, and American Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,566 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,048 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,905 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Frontier
5.8
Fair
3,103 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Food

7.3

Boarding

8.1

Comfort

7.9

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Denver to Santo Domingo?

    For as low as $463, JetBlue can have you in Santo Domingo from Denver in 11h 54m. The distance from Denver to Santo Domingo is about 2551 mi.

  • What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

    Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $256 on this airline. Additional options worth looking into are JetBlue and Copa Airlines, starting at $433 and $489 round-trip. Frontier is 57% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.

  • Can I find deals for business class flights from Denver to Santo Domingo?

    Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santo Domingo?

    Currently, October is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $253). Flying from Denver to Santo Domingo in August is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 5 airlines flying from Denver to Santo Domingo

Discover the top 5 airlines that operate flights from Denver to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$256Average$491FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$433Average$664FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$489Average$866FlexibilityNo cancel feeOn-time70%
DeltaCheapest$496Average$575FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$496Average$617FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.