What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $426 on this airline. Additional options worth looking into are Copa Airlines and Delta, starting at $495 and $507 round-trip. Frontier is 30% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Denver to Santo Domingo one-way?

For one-way options, check prices for Frontier. According to our data, you can fly for as low as $207. Users have also found prices from $221 and $242 on JetBlue and Delta, respectively.

What is the cheapest day to fly from Denver to Santo Domingo?

Travelers seeking maximum savings on their Denver to Santo Domingo flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Denver to Santo Domingo?

Consider American Airlines, JetBlue or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Denver to Santo Domingo.

What is the cheapest day to fly round-trip from Denver to Santo Domingo?

Flights from Denver to Santo Domingo are found to be more expensive on Saturday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santo Domingo.

How far in advance should I book a flight from Denver to Santo Domingo?

Users have found that booking a flight from Denver to Santo Domingo at least 37 days early can save you up to 17% on average compared to booking a flight this week. If booking 37 days before your flight isn’t an option for you, users have found flights from Denver to Santo Domingo for as little as $496 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $575 for flights departing within the next 3 days.

What is the cheapest month to fly from Denver to Santo Domingo?

The best pricing can be found in the month of September. Prices to Santo Domingo from Denver average $609. You can even find prices in September for less than $609, as users have found deals to Santo Domingo from as low as $424. The month of December appears to be one of the more expensive times to travel to Santo Domingo from Denver. Flying in the targeted month can save you up to 33%.

Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.

Can I find deals for business class flights from Denver to Santo Domingo?

Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$174+ Flights from Denver to Santo Domingo

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in September or October, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Denver to Santo Domingo

Round-trip from	$391 (Kiwi.com)
One-way from	$174 (Trip.com)
Popular in	December
Cheapest in	September
Average price	$695

From Denver Intl to Santo Domingo Las Americas

Search Deals

One-way flight from Denver Intl to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($106 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Mon 8/1112:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Sat 8/233:35 pmSDQ - DEN

1 stop18h 46mMultiple Airlines

Deal found 6/12

$391

Mon 6/2312:59 amDEN - SDQ

1 stop21h 20mFrontier

Tue 7/11:49 amSDQ - DEN

1 stop9h 11mFrontier

Deal found 6/10

$426

Wed 11/268:19 pmDEN - SDQ

1 stop16h 56mCopa Airlines

Fri 12/58:51 amSDQ - DEN

1 stop11h 19mCopa Airlines

Deal found 6/10

$495

Tue 8/1212:11 pmDEN - SDQ

1 stop10h 41mDelta

Sat 8/233:03 pmSDQ - DEN

1 stop9h 52mDelta

Deal found 6/12

$507

Sat 8/95:00 amDEN - SDQ

2 stops13h 30mAmerican Airlines

Thu 8/1410:25 amSDQ - DEN

1 stop14h 34mAmerican Airlines

Deal found 6/11

$531

Fri 6/2011:54 pmDEN - SDQ

1 stop9h 45mJetBlue

Fri 7/181:05 pmSDQ - DEN

1 stop11h 54mJetBlue

Deal found 6/9

$615

Best flights from Denver to Santo Domingo
Discover carefully curated flight deals from Denver to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Mon 8/1112:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Sat 8/233:35 pmSDQ - DEN

1 stop18h 46mMultiple Airlines

Deal found 6/12

$391

Mon 6/2312:59 amDEN - SDQ

1 stop21h 20mFrontier

Tue 7/11:49 amSDQ - DEN

1 stop9h 11mFrontier

Deal found 6/10

$426

Wed 11/268:19 pmDEN - SDQ

1 stop16h 56mCopa Airlines

Fri 12/58:51 amSDQ - DEN

1 stop11h 19mCopa Airlines

Deal found 6/10

$495

Tue 8/1212:11 pmDEN - SDQ

1 stop10h 41mDelta

Sat 8/233:03 pmSDQ - DEN

1 stop9h 52mDelta

Deal found 6/12

$507

Sat 8/95:00 amDEN - SDQ

2 stops13h 30mAmerican Airlines

Thu 8/1410:25 amSDQ - DEN

1 stop14h 34mAmerican Airlines

Deal found 6/11

$531

Fri 7/1111:25 amDEN - SDQ

1 stop14h 24mJetBlue

Sun 7/272:05 amSDQ - DEN

1 stop10h 20mJetBlue

Deal found 6/11

$678

Last-minute flights from Denver to Santo Domingo
Discover last-minute flight deals from Denver to Santo Domingo. Data last updated June 12, 2025 and is based on user searches.

Wed 6/1811:59 pmDEN - SDQ

1 stop10h 29mDelta

Wed 7/166:00 amSDQ - DEN

2 stops16h 24mDelta

Deal found 6/9

$531

Thu 6/191:46 pmDEN - SDQ

1 stop8h 33mFrontier

Tue 7/151:48 amSDQ - DEN

1 stop9h 14mFrontier

Deal found 6/9

$435

Thu 6/1911:40 pmDEN - SDQ

1 stop7h 33mAmerican Airlines

Thu 7/1710:15 amSDQ - DEN

2 stops14h 46mAmerican Airlines

Deal found 6/9

$620

Fri 6/2011:54 pmDEN - SDQ

1 stop9h 45mJetBlue

Fri 7/181:05 pmSDQ - DEN

1 stop11h 54mJetBlue

Deal found 6/9

$615

Sun 6/2212:34 amDEN - SDQ

1 stop13h 55mMultiple Airlines

Wed 7/2310:55 amSDQ - DEN

2 stops23h 07mMultiple Airlines

Deal found 6/9

$597

Mon 6/2312:59 amDEN - SDQ

1 stop21h 20mFrontier

Tue 7/11:49 amSDQ - DEN

1 stop9h 11mFrontier

Deal found 6/10

$426

Wed 7/212:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Thu 7/177:00 pmSDQ - DEN

1 stop15h 21mMultiple Airlines

Deal found 6/11

$434

Wed 7/2311:55 pmDEN - SDQ

1 stop13h 25mAmerican Airlines

Tue 7/297:00 amSDQ - DEN

2 stops15h 05mAmerican Airlines

Deal found 6/11

$575

Thu 7/2410:42 pmDEN - SDQ

1 stop15h 35mCopa Airlines

Thu 8/215:23 amSDQ - DEN

1 stop14h 40mCopa Airlines

Deal found 6/10

$540

One-way flights from Denver to Santo Domingo
Search for one-way flight options from Denver to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated June 12, 2025.

Thu 9/1812:34 amDEN - SDQ

1 stop13h 55mMultiple Airlines

Deal found 6/11

$174

Mon 7/2812:59 amDEN - SDQ

1 stop21h 29mFrontier

Deal found 6/11

$207

Tue 8/1911:00 amDEN - SDQ

1 stop14h 03mJetBlue

Deal found 6/10

$221

Sun 8/312:59 amDEN - SDQ

1 stop10h 13mDelta

Deal found 6/12

$242

Mon 8/411:59 pmDEN - SDQ

2 stops16h 21mAmerican Airlines

Deal found 6/12

$257

Tue 8/199:40 amDEN - SDQ

3 stops14h 10mUnited Airlines

Deal found 6/10

$1,697

Fri 7/2512:49 pmDEN - SDQ

3 stops50h 11mCondor

Deal found 6/11

$1,905

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 8/11

12:34 am-9:45 pm

1 stop19h 11m

Santo Domingo Las Americas

Sat 8/23

3:35 pm-8:21 am

1 stop18h 46m

$391

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 6/23

12:59 am-12:19 am

1 stop21h 20m

Santo Domingo Las Americas

Tue 7/1

1:49 am-9:00 am

1 stop9h 11m

$426

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 11/26

8:19 pm-4:15 pm

1 stop16h 56m

Santo Domingo Las Americas

Fri 12/5

8:51 am-5:10 pm

1 stop11h 19m

$495

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Tue 8/12

12:11 pm-12:52 am

1 stop10h 41m

Santo Domingo Las Americas

Sat 8/23

3:03 pm-10:55 pm

1 stop9h 52m

$507

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sat 8/9

7:18 am-8:30 pm

2 stops11h 12m

Santo Domingo Las Americas

Thu 8/14

10:25 am-11:41 pm

2 stops15h 16m

$531

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Fri 7/11

11:25 am-3:49 am

1 stop14h 24m

Santo Domingo Las Americas

Sun 7/27

2:05 am-10:25 am

1 stop10h 20m

$678

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 9/18

12:34 am-4:29 pm

1 stop13h 55m

$174

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 7/28

12:59 am-12:28 am

1 stop21h 29m

$207

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Tue 8/19

11:00 am-3:03 am

1 stop14h 03m

$221

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sun 8/3

12:59 am-1:12 pm

1 stop10h 13m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 13 results

Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

The price you pay for your flight from Denver to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SDQ?

It’s optimal to fly from Denver to Santo Domingo in the afternoon. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.

Rainfall in Santo Domingo by month

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

Temperature in Santo Domingo by month

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines and United Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,950 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,451 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,790 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

JetBlue

7.3

Good

2,925 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,950 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Denver to Santo Domingo round-trip?
Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $426 on this airline. Additional options worth looking into are Copa Airlines and Delta, starting at $495 and $507 round-trip. Frontier is 30% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Denver to Santo Domingo one-way?
For one-way options, check prices for Frontier. According to our data, you can fly for as low as $207. Users have also found prices from $221 and $242 on JetBlue and Delta, respectively.
Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.
Can I find deals for business class flights from Denver to Santo Domingo?
Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Denver to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$256	Average$512	FlexibilityNo cancel fee	On-time62%
JetBlue	Cheapest$421	Average$643	FlexibilityNo cancel fee	On-time62%
Copa Airlines	Cheapest$462	Average$657	FlexibilityNo cancel fee	On-time70%
American Airlines	Cheapest$476	Average$633	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$490	Average$566	FlexibilityNo cancel fee	On-timeN/A

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$174+ Cheap flights from Denver (DEN) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in September or October, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Denver to Santo Domingo

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo DomingoExplore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santo Domingo. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from Denver to Santo Domingo?

What is the cheapest time of day to fly from DEN to SDQ?

Find hourly flight availability from Denver to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Rainfall in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average rainfall totals by month.

Temperature in Santo Domingo by month

Plan your trip to Santo Domingo by taking into account the average temperature totals by month.

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines and United Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

What are the cheapest airlines to fly from Denver to Santo Domingo one-way?

Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

How can I find direct flights from Denver to Santo Domingo?

Can I find deals for business class flights from Denver to Santo Domingo?

What is the cheapest month to book a flight from Denver to Santo Domingo?

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Top 5 airlines flying from Denver to Santo Domingo

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Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.