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Santo Domingo

$175+ Cheap flights from Denver (DEN) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SDQ
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in October or July, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Denver to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 16, 2025.

Round-trip from

$381
(Kiwi.com)

One-way from

$175
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$585
From Denver Intl to Santo Domingo Las Americas
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One-way flight from Denver Intl to Santo Domingo Las Americas
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Highest demand for flights based on searches. 13% potential increase in price ($95 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:21 pmDEN - SDQ
2 stops23h 24mMultiple Airlines
Wed 10/2210:19 amSDQ - DEN
1 stop24h 14mMultiple Airlines
Deal found 9/15$381
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/912:38 pmDEN - SDQ
2 stops25h 51mMultiple Airlines
Thu 10/163:35 pmSDQ - DEN
1 stop18h 58mMultiple Airlines
Deal found 9/15$398
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/298:13 pmDEN - SDQ
2 stops16h 35mMultiple Airlines
Sat 11/13:35 pmSDQ - DEN
1 stop19h 58mMultiple Airlines
Deal found 9/15$405
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/37:00 amDEN - SDQ
2 stops31h 50mMultiple Airlines
Mon 12/88:01 amSDQ - DEN
1 stop18h 03mMultiple Airlines
Deal found 9/15$407
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:16 amDEN - SDQ
2 stops36h 32mMultiple Airlines
Wed 11/510:19 amSDQ - DEN
1 stop25h 14mMultiple Airlines
Deal found 9/13$415
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/21:12 pmDEN - SDQ
2 stops24h 48mMultiple Airlines
Sun 10/53:35 pmSDQ - DEN
1 stop18h 55mMultiple Airlines
Deal found 9/14$416
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:08 pmDEN - SDQ
2 stops15h 46mMultiple Airlines
Fri 10/1710:19 amSDQ - DEN
1 stop24h 14mMultiple Airlines
Deal found 9/15$425
This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:46 amDEN - SDQ
1 stop15h 06mJetBlue
Thu 12/42:06 pmSDQ - DEN
1 stop11h 01mJetBlue
Deal found 9/16$427
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:34 amDEN - SDQ
1 stop12h 55mMultiple Airlines
Mon 11/106:55 pmSDQ - DEN
2 stops26h 21mMultiple Airlines
Deal found 9/15$428
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/109:05 pmDEN - SDQ
2 stops25h 34mMultiple Airlines
Mon 12/158:01 amSDQ - DEN
1 stop18h 03mMultiple Airlines
Deal found 9/15$435

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Fly from

Denver

Fly to

Santo Domingo

Route

Depart

Return

Price

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 12/3

7:00 am-5:50 pm

2 stops31h 50m

Santo Domingo Las Americas

Mon 12/8

8:01 am-11:04 pm

1 stop18h 03m

$407

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Tue 10/28

12:16 am-2:48 pm

2 stops36h 32m

Santo Domingo Las Americas

Wed 11/5

10:19 am-8:33 am

1 stop25h 14m

$415

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sat 10/11

8:22 pm-2:48 pm

2 stops16h 26m

Santo Domingo Las Americas

Thu 10/16

3:35 pm-8:33 am

1 stop18h 58m

$416

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 10/2

1:12 pm-4:00 pm

2 stops24h 48m

Santo Domingo Las Americas

Sun 10/5

3:35 pm-8:30 am

1 stop18h 55m

$416

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 11/27

10:46 am-4:52 am

1 stop15h 06m

Santo Domingo Las Americas

Thu 12/4

11:12 am-10:07 pm

1 stop13h 55m

$427

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Sun 11/2

12:34 am-4:29 pm

1 stop12h 55m

Santo Domingo Las Americas

Mon 11/10

6:55 pm-6:16 pm

2 stops26h 21m

$428

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 12/10

9:05 pm-1:39 am

2 stops25h 34m

Santo Domingo Las Americas

Mon 12/15

8:01 am-11:04 pm

1 stop18h 03m

$435

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 9/22

6:10 am-9:45 pm

2 stops37h 35m

Santo Domingo Las Americas

Sun 10/5

3:35 pm-8:30 am

1 stop18h 55m

$446

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 10/22

12:34 am-9:45 pm

1 stop19h 11m

$175

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Fri 11/14

11:51 am-2:09 am

1 stop11h 18m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 14 results
1
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Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santo Domingo. Price data was last updated on September 12, 2025.

The price you pay for your flight from Denver to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SDQ?

Find hourly flight availability from Denver to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

It’s optimal to fly from Denver to Santo Domingo in the afternoon. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Denver to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated September 16, 2025.
See what other customers who have flown with Delta, Copa Airlines, and American Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
JetBlue
7.2
Good
2,914 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.8
Fair
3,174 reviews
Delta
8.0
Very good
7,957 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

    Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $256 on this airline. Additional options worth looking into are JetBlue and Copa Airlines, starting at $420 and $489 round-trip. Frontier is 57% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.

  • Can I find deals for business class flights from Denver to Santo Domingo?

    Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santo Domingo?

    Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top 5 airlines flying from Denver to Santo Domingo

Discover the top 5 airlines that operate flights from Denver to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$256Average$512FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$420Average$600FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$489Average$795FlexibilityNo cancel feeOn-time70%
DeltaCheapest$490Average$575FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$496Average$620FlexibilityNo cancel feeOn-time71%

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