What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $256 on this airline. Additional options worth looking into are JetBlue and Copa Airlines, starting at $421 and $462 round-trip. Frontier is 57% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Denver to Santo Domingo?

Travelers seeking maximum savings on their Denver to Santo Domingo flight should consider departing on Monday afternoons when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santo Domingo ranges from 1.6 - 6.7 inches per month. May is typically the wettest month, when rainfall can reach 6.7 in. February is typically the driest time to visit Santo Domingo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 75.2 F).

What are the most popular airlines that fly from Denver to Santo Domingo?

Consider American Airlines, JetBlue or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Denver to Santo Domingo.

What is the cheapest day to fly round-trip from Denver to Santo Domingo?

Flights from Denver to Santo Domingo are found to be more expensive on Saturday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Santo Domingo.

How far in advance should I book a flight from Denver to Santo Domingo?

Users have found that booking a flight from Denver to Santo Domingo at least 37 days early can save you up to 17% on average compared to booking a flight this week. If booking 37 days before your flight isn’t an option for you, users have found flights from Denver to Santo Domingo for as little as $496 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $575 for flights departing within the next 3 days.

What is the cheapest month to fly from Denver to Santo Domingo?

The best pricing can be found in the month of September. Prices to Santo Domingo from Denver average $605. You can even find prices in September for less than $605, as users have found deals to Santo Domingo from as low as $441. The month of December appears to be one of the more expensive times to travel to Santo Domingo from Denver. Flying in the targeted month can save you up to 29%.

Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Denver to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.

Can I find deals for business class flights from Denver to Santo Domingo?

Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$174+ Flights from Denver to Santo Domingo

Q: How much does it cost to fly round-trip from Denver to Santo Domingo?

Airfare is below average for this route at the moment. Denver to Santo Domingo flights typically cost between $531 and $673 in September. The cheapest round-trip price found within the last 3 days was $381 on Multiple Airlines (Sep 17-Sep 23).

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Find cheap flights from Denver to Santo Domingo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in September or October, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Denver to Santo Domingo

Round-trip from	$381 (Kiwi.com)
One-way from	$174 (Trip.com)
Popular in	December
Cheapest in	September
Average price	$632

From Denver Intl to Santo Domingo Las Americas

Search Deals

One-way flight from Denver Intl to Santo Domingo Las Americas

Search Deals

Highest demand for flights based on searches. 14% potential increase in price ($101 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Wed 9/176:55 pmDEN - SDQ

1 stop24h 50mMultiple Airlines

Tue 9/235:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/17

$381

Mon 9/812:04 amDEN - SDQ

1 stop10h 11mMultiple Airlines

Tue 9/165:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/16

$423

Tue 10/79:19 pmDEN - SDQ

2 stops15h 29mMultiple Airlines

Thu 10/163:35 pmSDQ - DEN

1 stop18h 58mMultiple Airlines

Deal found 8/16

$424

Thu 10/96:15 amDEN - SDQ

2 stops13h 30mMultiple Airlines

Wed 10/2210:19 amSDQ - DEN

1 stop24h 14mMultiple Airlines

Deal found 8/18

$452

Mon 9/2211:59 pmDEN - SDQ

2 stops11h 26mJetBlue

Mon 10/612:47 pmSDQ - DEN

1 stop12h 17mJetBlue

Deal found 8/16

$457

Fri 10/3112:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Sat 11/86:55 pmSDQ - DEN

2 stops17h 08mMultiple Airlines

Deal found 8/18

$460

Best flights from Denver to Santo Domingo
Discover carefully curated flight deals from Denver to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 18, 2025.

Wed 9/176:55 pmDEN - SDQ

1 stop24h 50mMultiple Airlines

Tue 9/235:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/17

$381

Mon 9/2211:59 pmDEN - SDQ

2 stops11h 26mJetBlue

Mon 10/612:47 pmSDQ - DEN

1 stop12h 17mJetBlue

Deal found 8/16

$457

Mon 9/812:04 amDEN - SDQ

1 stop10h 11mMultiple Airlines

Tue 9/165:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/18

$415

Tue 10/79:19 pmDEN - SDQ

2 stops15h 29mMultiple Airlines

Thu 10/163:35 pmSDQ - DEN

1 stop18h 58mMultiple Airlines

Deal found 8/16

$424

Thu 10/96:15 amDEN - SDQ

2 stops13h 30mMultiple Airlines

Wed 10/2210:19 amSDQ - DEN

1 stop24h 14mMultiple Airlines

Deal found 8/18

$452

Fri 10/3112:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Sat 11/86:55 pmSDQ - DEN

2 stops17h 08mMultiple Airlines

Deal found 8/18

$460

Last-minute flights from Denver to Santo Domingo
Discover last-minute flight deals from Denver to Santo Domingo. Data last updated August 18, 2025 and is based on user searches.

Thu 8/282:09 pmDEN - SDQ

1 stop17h 16mAmerican Airlines

Tue 9/97:00 amSDQ - DEN

1 stop18h 01mAmerican Airlines

Deal found 8/17

$527

Mon 9/812:04 amDEN - SDQ

1 stop10h 11mMultiple Airlines

Tue 9/165:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/16

$423

Tue 9/911:59 pmDEN - SDQ

1 stop16h 01mDelta

Tue 9/161:45 pmSDQ - DEN

1 stop10h 50mDelta

Deal found 8/18

$487

Wed 9/1011:40 amDEN - SDQ

2 stops16h 19mMultiple Airlines

Thu 9/113:35 pmSDQ - DEN

1 stop18h 55mMultiple Airlines

Deal found 8/17

$520

Wed 9/176:55 pmDEN - SDQ

1 stop24h 50mMultiple Airlines

Tue 9/235:05 pmSDQ - DEN

2 stops18h 28mMultiple Airlines

Deal found 8/17

$381

Sun 9/2112:59 amDEN - SDQ

1 stop10h 25mDelta

Mon 10/62:56 pmSDQ - DEN

1 stop8h 45mDelta

Deal found 8/18

$477

Mon 9/2211:59 pmDEN - SDQ

2 stops11h 26mJetBlue

Mon 10/612:47 pmSDQ - DEN

1 stop12h 17mJetBlue

Deal found 8/16

$457

One-way flights from Denver to Santo Domingo
Search for one-way flight options from Denver to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated August 18, 2025.

Wed 9/106:55 pmDEN - SDQ

1 stop24h 50mMultiple Airlines

Deal found 8/17

$174

Wed 10/2912:34 amDEN - SDQ

1 stop19h 11mMultiple Airlines

Deal found 8/18

$176

Fri 10/36:55 pmDEN - SDQ

1 stop24h 50mMultiple Airlines

Deal found 8/17

$180

Thu 10/3011:51 amDEN - SDQ

1 stop9h 58mJetBlue

Deal found 8/18

$221

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 9/17

6:55 pm-9:45 pm

1 stop24h 50m

Santo Domingo Las Americas

Tue 9/23

5:05 pm-9:33 am

2 stops18h 28m

$381

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 9/8

12:04 am-12:15 pm

1 stop10h 11m

Santo Domingo Las Americas

Tue 9/16

5:05 pm-9:33 am

2 stops18h 28m

$415

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Tue 10/7

9:19 pm-2:48 pm

2 stops15h 29m

Santo Domingo Las Americas

Thu 10/16

3:35 pm-8:33 am

1 stop18h 58m

$424

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 10/9

6:15 am-9:45 pm

2 stops13h 30m

Santo Domingo Las Americas

Wed 10/22

10:19 am-8:33 am

1 stop24h 14m

$452

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Mon 9/22

11:59 pm-1:25 pm

2 stops11h 26m

Santo Domingo Las Americas

Mon 10/6

12:47 pm-11:04 pm

1 stop12h 17m

$457

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Fri 10/31

12:34 am-9:45 pm

1 stop19h 11m

Santo Domingo Las Americas

Sat 11/8

6:55 pm-9:03 am

2 stops17h 08m

$460

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 9/10

6:55 pm-9:45 pm

1 stop24h 50m

$174

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Wed 10/29

12:34 am-9:45 pm

1 stop19h 11m

$176

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Fri 10/3

6:55 pm-9:45 pm

1 stop24h 50m

$180

DenverSanto Domingo

DEN - SDQ

DENSDQ

Denver Intl

Thu 10/30

11:51 am-11:49 pm

1 stop9h 58m

$221

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

The price you pay for your flight from Denver to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SDQ?

It’s optimal to fly from Denver to Santo Domingo in the afternoon. By choosing this option you can save up to 33% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Denver to Santo Domingo?

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines, and American Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,510 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

JetBlue

7.2

Good

2,915 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Frontier

5.8

Fair

3,212 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Denver to Santo Domingo round-trip?
Our cheapest airline available from Denver to Santo Domingo is Frontier. Our recent data shows that you can find tickets from as low as $256 on this airline. Additional options worth looking into are JetBlue and Copa Airlines, starting at $421 and $462 round-trip. Frontier is 57% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Denver to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Denver to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santo Domingo.
Can I find deals for business class flights from Denver to Santo Domingo?
Yes. Cheapflights offers flight deals from Denver to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Denver to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Denver to Santo Domingo (average of $362). Flying from Denver to Santo Domingo in December is currently the most expensive (average of $583). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Denver to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$256	Average$512	FlexibilityNo cancel fee	On-time62%
JetBlue	Cheapest$421	Average$625	FlexibilityNo cancel fee	On-time62%
Copa Airlines	Cheapest$462	Average$726	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$490	Average$565	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$496	Average$628	FlexibilityNo cancel fee	On-time71%

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$174+ Cheap flights from Denver (DEN) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Denver to Santo Domingo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Denver Intl to Santo Domingo Las Americas are usually found in September or October, booked 90 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Denver to Santo Domingo

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Denver to Santo Domingo

Cheapest flights from Denver to Santo DomingoExplore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Denver to Santo Domingo that are best for you.

Best time to book a flight from Denver to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Denver with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santo Domingo

How far ahead should I book a flight from Denver to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santo Domingo. Price data was last updated on August 8, 2025.

What is the cheapest month to book a flight from Denver to Santo Domingo?

What is the cheapest time of day to fly from DEN to SDQ?

Find hourly flight availability from Denver to Santo Domingo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

How much does it cost to fly round-trip from Denver to Santo Domingo?

Reviews of airlines servicing Santo Domingo

See what other customers who have flown with Delta, Copa Airlines, and American Airlines from Denver to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Denver to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Denver to Santo Domingo round-trip?

Can I find deals for flights from Denver to Santo Domingo that include hotel bookings?

How can I find direct flights from Denver to Santo Domingo?

Can I find deals for business class flights from Denver to Santo Domingo?

What is the cheapest month to book a flight from Denver to Santo Domingo?

Traveling to a place near Santo Domingo?

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Alternative routes for Denver to Santo Domingo

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Top 5 airlines flying from Denver to Santo Domingo

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Cheapest flights from Denver to Santo Domingo
Explore the most affordable flight options available from Denver to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.