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Santo Domingo

$200+ Cheap flights from Cali (CLO) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — SDQ
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Cali to Santo Domingo

Cheapest flights from Cali to Santo Domingo
Explore the most affordable flight options available from Cali to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:03 am
CLO
-
SDQ
1 stop4h 47m
Copa Airlines
Tue 2/176:00 am
SDQ
-
CLO
1 stop12h 50m
Copa Airlines
Deal found 2/2$342
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2410:06 pm
CLO
-
SDQ
1 stop14h 46m
Multiple Airlines
Sat 8/12:42 pm
SDQ
-
CLO
1 stop17h 08m
Multiple Airlines
Deal found 2/3$346
This Copa Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2812:02 pm
CLO
-
SDQ
1 stop13h 16m
Copa Airlines
Fri 4/1012:38 pm
SDQ
-
CLO
1 stop5h 58m
Copa Airlines
Deal found 2/1$347
This Mytrip deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 am
CLO
-
SDQ
1 stop7h 49m
Multiple Airlines
Wed 6/36:50 pm
SDQ
-
CLO
1 stop12h 35m
Multiple Airlines
Deal found 2/1$349
This Copa Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/13:10 pm
CLO
-
SDQ
1 stop10h 10m
Copa Airlines
Tue 4/76:02 am
SDQ
-
CLO
1 stop9h 08m
Copa Airlines
Deal found 2/4$353
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:10 pm
CLO
-
SDQ
1 stop10h 15m
Copa Airlines
Mon 5/1112:10 pm
SDQ
-
CLO
1 stop6h 26m
Copa Airlines
Deal found 2/3$355
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:03 pm
CLO
-
SDQ
2 stops24h 52m
Multiple Airlines
Tue 3/171:58 pm
SDQ
-
CLO
2 stops17h 25m
Multiple Airlines
Deal found 2/3$357
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:45 am
CLO
-
SDQ
1 stop7h 04m
Multiple Airlines
Tue 3/101:58 pm
SDQ
-
CLO
2 stops17h 25m
Multiple Airlines
Deal found 2/3$360
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/129:22 pm
CLO
-
SDQ
1 stop15h 33m
Multiple Airlines
Sat 2/287:35 am
SDQ
-
CLO
2 stops24h 58m
Multiple Airlines
Deal found 2/3$363
This Copa Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:03 am
CLO
-
SDQ
1 stop7h 06m
Copa Airlines
Thu 11/56:00 am
SDQ
-
CLO
1 stop12h 37m
Copa Airlines
Deal found 2/2$377
This Copa Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2212:02 pm
CLO
-
SDQ
1 stop9h 38m
Copa Airlines
Fri 3/276:41 pm
SDQ
-
CLO
1 stop5h 53m
Copa Airlines
Deal found 2/3$383

Find flight deals from Cali to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$342
(Copa Airlines)

One-way from

$257
(Copa Airlines)

Popular in

December

Cheapest in

September

Average price

$348
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Santo Domingo Las Americas flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas
Search Deals
One-way flight from Cali Alfonso B. Aragon Intl to Santo Domingo Las Americas
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

Fly from

Cali

Fly to

Santo Domingo

Route

Depart

Return

Price

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Mon 3/16

12:02 pm-2:18 am

1 stop13h 16m

Santo Domingo Las Americas

Sat 3/21

8:48 am-5:49 pm

1 stop10h 01m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 2/19

8:48 am-6:05 pm

1 stop8h 17m

Santo Domingo Las Americas

Thu 2/26

7:05 pm-11:36 pm

1 stop5h 31m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sun 3/15

8:48 am-10:40 pm

1 stop12h 52m

Santo Domingo Las Americas

Mon 3/23

8:48 am-2:09 pm

1 stop6h 21m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Sun 3/1

5:03 am-10:48 am

1 stop4h 45m

Santo Domingo Las Americas

Fri 3/6

6:41 pm-11:34 pm

1 stop5h 53m

$342

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 3/5

5:45 am-6:42 pm

1 stop11h 57m

$200

CaliSanto Domingo

CLO - SDQ

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 7/16

5:00 am-4:15 pm

1 stop10h 15m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

  • Most accurate provider: When it comes to deals on Cali-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cali-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cali-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Santo Domingo. Price data was last updated on January 30, 2026.

The best time to book flights from Cali to Santo Domingo is 87 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cali to Santo Domingo?

Currently, June is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $144). Flying from Cali to Santo Domingo in April is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cali to Santo Domingo?

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated February 4, 2026.
Peruse reviews from past customers who have flown with Copa Airlines and Avianca from Cali to Santo Domingo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,556 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Boarding

7.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,556 reviews
Copa Airlines
7.5
Good
1,556 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Boarding

7.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Avianca
6.5
Okay
2,499 reviews
Copa Airlines
7.5
Good
1,556 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Boarding

7.8

Crew

8.1

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Cali to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Santo Domingo?

    There are many flights that can get you from Cali to Santo Domingo in 13h 16m. Fly via Copa Airlines to get the fastest option. The distance from Cali to Santo Domingo is about 1123 mi.

  • What are the cheapest airlines flying from Cali to Santo Domingo round-trip?

    Flying on Copa Airlines is currently your cheapest option to Santo Domingo, with prices starting at $310. Another option worth looking into is Avianca, starting at $350 round trip. Users have found that Copa Airlines is 15% cheaper than the other options available to this destination.

  • Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.

  • Can I find deals for business class flights from Cali to Santo Domingo?

    Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Santo Domingo?

    Currently, June is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of $144). Flying from Cali to Santo Domingo in April is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Cali to Santo Domingo

Discover the top 2 airlines that operate flights from Cali to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$310Average$375FlexibilityNo cancel feeOn-time70%
AviancaCheapest$350Average$390FlexibilityNo cancel feeOn-time71%

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