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$136+ Cheap flights from Santo Domingo (SDQ) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/24. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — CLO
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheapflights Tip: The best prices from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl are usually found in September or August, booked 51 days in advance, depart on a Tuesday or Wednesday and return on a Friday

Cheap flight deals from Santo Domingo to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$291
(Kiwi.com)

One-way from

$136
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$350
From Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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One-way flight from Santo Domingo Las Americas to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Cali

Cheapest flights from Santo Domingo to Cali
Explore the most affordable flight options available from Santo Domingo to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/222:10 amSDQ - CLO
1 stop5h 58mMultiple Airlines
Wed 8/274:31 pmCLO - SDQ
1 stop7h 49mMultiple Airlines
Deal found 7/2$291
This Copa Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/208:57 amSDQ - CLO
1 stop6h 24mCopa Airlines
Sun 8/314:42 amCLO - SDQ
1 stop7h 27mCopa Airlines
Deal found 7/3$374
This Avianca deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:15 pmSDQ - CLO
1 stop6h 29mAvianca
Sun 11/99:10 amCLO - SDQ
1 stop7h 10mAvianca
Deal found 7/3$377
This OneTravel deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure OneTravel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/232:53 amSDQ - CLO
1 stop11h 27mSpirit Airlines
Fri 9/262:17 pmCLO - SDQ
1 stop10h 38mSpirit Airlines
Deal found 7/2$466
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/157:00 amSDQ - CLO
1 stop14h 45mAmerican Airlines
Mon 7/2112:30 amCLO - SDQ
1 stop16h 50mAmerican Airlines
Deal found 7/1$1,339

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Santo Domingo to Cali that are best for you.

Fly from

Santo Domingo

Fly to

Cali

Route

Depart

Return

Price

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 8/22

2:10 am-7:08 am

1 stop5h 58m

Cali Alfonso B. Aragon Intl

Wed 8/27

4:31 pm-1:20 am

1 stop7h 49m

$291

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 8/20

8:57 am-2:21 pm

1 stop6h 24m

Cali Alfonso B. Aragon Intl

Sun 8/31

4:42 am-1:09 pm

1 stop7h 27m

$374

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Fri 11/7

6:15 pm-11:44 pm

1 stop6h 29m

Cali Alfonso B. Aragon Intl

Sun 11/9

9:10 am-5:20 pm

1 stop7h 10m

$377

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Tue 9/23

2:53 am-1:20 pm

1 stop11h 27m

Cali Alfonso B. Aragon Intl

Fri 9/26

2:17 pm-1:55 am

1 stop10h 38m

$466

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Tue 7/15

7:00 am-8:45 pm

1 stop14h 45m

Cali Alfonso B. Aragon Intl

Mon 7/21

12:30 am-6:20 pm

1 stop16h 50m

$1,339

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Wed 9/24

2:10 am-6:38 am

1 stop5h 28m

$136

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Tue 7/8

8:55 am-2:22 pm

1 stop6h 27m

$177

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Mon 11/10

11:50 am-11:04 pm

2 stops12h 14m

$227

Santo DomingoCali

SDQ - CLO

SDQCLO

Santo Domingo Las Americas

Sun 11/9

3:45 am-2:25 pm

1 stop11h 40m

$709

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Santo Domingo to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Cali

How far ahead should I book a flight from Santo Domingo to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Cali. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from Santo Domingo to Cali, you should look to book at least 51 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santo Domingo to Cali?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with Copa Airlines, American Airlines, and Avianca from Santo Domingo to Cali to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,467 reviews

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,467 reviews
Copa Airlines
7.5
Good
1,467 reviews

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.5
Good
1,467 reviews

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,363 reviews
Copa Airlines
7.5
Good
1,467 reviews

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Spirit Airlines
6.3
Okay
8,086 reviews
Copa Airlines
7.5
Good
1,467 reviews

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santo Domingo to Cali round-trip?

    Flying on Copa Airlines is currently your cheapest option to Cali, with prices starting at $374. Additional round-trip tickets that might be worth considering are offered by Avianca and Spirit Airlines, with the lowest prices starting at $413 and $466, respectively.

  • Can I find deals for flights from Santo Domingo to Cali that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Cali.

  • Can I find deals for business class flights from Santo Domingo to Cali?

    Yes. Cheapflights offers flight deals from Santo Domingo to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Cali?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Cali (average of $351). Flying from Santo Domingo to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santo Domingo to Cali

Discover the top 2 airlines that operate flights from Santo Domingo to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$323Average$350FlexibilityNo cancel feeOn-time70%
AviancaCheapest$325Average$362FlexibilityNo cancel feeOn-time71%

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