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Santiago de los Caballeros

$302+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — STI
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This JetBlue deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:30 pm
SFO
-
STI
1 stop12h 15m
JetBlue
Thu 5/141:57 pm
STI
-
SFO
1 stop13h 57m
JetBlue
Deal found 1/22$421
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:45 pm
SFO
-
STI
1 stop10h 59m
JetBlue
Mon 3/99:22 am
STI
-
SFO
1 stop27h 07m
JetBlue
Deal found 1/21$430
This JetBlue deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:25 am
SFO
-
STI
1 stop14h 22m
JetBlue
Tue 3/318:30 am
STI
-
SFO
1 stop17h 12m
JetBlue
Deal found 1/21$455
This JetBlue deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:55 am
SFO
-
STI
1 stop10h 52m
JetBlue
Mon 3/239:13 am
STI
-
SFO
1 stop17h 13m
JetBlue
Deal found 1/21$483
This JetBlue deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/23:05 pm
SFO
-
STI
1 stop14h 34m
JetBlue
Fri 2/612:12 pm
STI
-
SFO
1 stop15h 17m
JetBlue
Deal found 1/19$492
This JetBlue deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1911:55 am
SFO
-
STI
1 stop10h 52m
JetBlue
Tue 3/249:13 am
STI
-
SFO
1 stop17h 03m
JetBlue
Deal found 1/22$550
This Expedia deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2912:20 pm
SFO
-
STI
1 stop12h 12m
JetBlue
Sat 2/712:12 pm
STI
-
SFO
1 stop15h 17m
JetBlue
Deal found 1/22$565
This Expedia deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/210:50 am
SFO
-
STI
1 stop12h 30m
JetBlue
Tue 2/312:12 pm
STI
-
SFO
1 stop26h 18m
JetBlue
Deal found 1/22$600
This Expedia deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/272:10 pm
SFO
-
STI
1 stop16h 18m
JetBlue
Mon 8/39:00 am
STI
-
SFO
1 stop28h 24m
JetBlue
Deal found 1/20$605
This JetBlue deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:55 am
SFO
-
STI
1 stop17h 15m
JetBlue
Fri 7/318:45 pm
STI
-
SFO
1 stop15h 09m
JetBlue
Deal found 1/20$627
This JetBlue deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:30 pm
SFO
-
STI
1 stop16h 26m
JetBlue
Thu 8/204:15 am
STI
-
SFO
1 stop16h 29m
JetBlue
Deal found 1/22$634

Find flight deals from San Francisco to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$421
(JetBlue)

One-way from

$302
(Expedia)

Popular in

December

Cheapest in

July

Average price

$509
Provider with most accurate pricing for San Francisco-Santiago de los Caballeros flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Santiago de los Caballeros flights.
Search Deals
From San Francisco to Santiago de los Caballeros
Search Deals
One-way flight from San Francisco to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($175 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($61 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

San Francisco

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 4/30

9:30 pm-12:45 pm

1 stop12h 15m

Santiago de los Caballeros

Thu 5/14

1:57 pm-12:54 am

1 stop13h 57m

$421

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 3/5

12:45 pm-3:44 am

1 stop10h 59m

Santiago de los Caballeros

Mon 3/9

9:22 am-9:29 am

1 stop27h 07m

$430

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 3/17

8:25 am-1:47 am

1 stop14h 22m

Santiago de los Caballeros

Tue 3/31

8:30 am-10:42 pm

1 stop17h 12m

$455

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 3/19

11:55 am-1:47 am

1 stop10h 52m

Santiago de los Caballeros

Mon 3/23

9:13 am-11:26 pm

1 stop17h 13m

$483

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Mon 2/2

3:05 pm-9:39 am

1 stop14h 34m

Santiago de los Caballeros

Fri 2/6

12:12 pm-11:29 pm

1 stop15h 17m

$492

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 3/19

11:55 am-1:47 am

1 stop10h 52m

Santiago de los Caballeros

Tue 3/24

9:13 am-11:16 pm

1 stop17h 03m

$550

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Mon 6/8

8:30 pm-3:56 pm

1 stop16h 26m

Santiago de los Caballeros

Thu 8/20

4:15 am-7:34 pm

1 stop18h 19m

$634

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 3/17

11:35 pm-8:29 pm

2 stops17h 54m

Santiago de los Caballeros

Tue 3/31

1:30 pm-11:59 pm

1 stop13h 29m

$643

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Wed 3/18

12:25 am-8:29 pm

2 stops17h 04m

Santiago de los Caballeros

Tue 3/24

7:00 am-8:14 pm

2 stops16h 14m

$643

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 7/21

10:05 am-1:58 am

1 stop12h 53m

$302

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 14 results
1
2

Compare providers for flights from San Francisco to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago de los Caballeros in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago de los Caballeros flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, July is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $281). Flying from San Francisco to Santiago de los Caballeros in May is currently the most expensive (average of $482). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated January 22, 2026.
Get a feel of what it's like to fly with American Airlines and JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,173 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,173 reviews
American Airlines
7.2
Good
11,173 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
JetBlue
7.2
Good
2,890 reviews
American Airlines
7.2
Good
11,173 reviews

Overall

7.2

Boarding

7.5

Food

6.4

Comfort

7.2

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santiago de los Caballeros?

    Airlines like JetBlue fly from San Francisco to Santiago de los Caballeros in about 12h 15m. The time it takes to get you to your destination can typically vary by up to . San Francisco and Santiago de los Caballeros are separated by a distance of 3336 mi.

  • What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?

    JetBlue, at $484, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros. An alternate airline flying to your destination would be American Airlines. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

  • Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

    Currently, July is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $281). Flying from San Francisco to Santiago de los Caballeros in May is currently the most expensive (average of $482). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from San Francisco to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from San Francisco to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$484Average$634FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$614Average$739FlexibilityNo cancel feeOn-time71%

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