What is the cheapest day to fly from San Francisco to Santiago de los Caballeros?

Travelers seeking maximum savings on their San Francisco to Santiago de los Caballeros flight should consider departing on Monday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the most popular airlines that fly from San Francisco to Santiago de los Caballeros?

When booking a flight from San Francisco to Santiago de los Caballeros, you may want to consider flying on American Airlines, JetBlue or Delta as they are the most popular for this route.

What is the cheapest day to fly round-trip from San Francisco to Santiago de los Caballeros?

Leaving on a Sunday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 77% on the overall cost on flights from San Francisco to Santiago de los Caballeros.

What is the cheapest month to fly from San Francisco to Santiago de los Caballeros?

July can be a great time to fly to Santiago de los Caballeros from San Francisco with a flight ticket averaging about $786. Cheapflights users have found deals in the month of July for as cheap as $289. The most expensive prices can be found in the month of February.

How can I find direct flights from San Francisco to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$217+ Flights from San Francisco to Santiago de los Caballeros

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Cheap flight deals from San Francisco to Santiago de los Caballeros

Round-trip from	$495 (Expedia)
One-way from	$217 (Kiwi.com)
Popular in	February
Cheapest in	July

From San Francisco to Santiago de los Caballeros

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One-way flight from San Francisco to Santiago de los Caballeros

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Highest demand for flights based on searches. 1% potential increase in price ($12 potential increase over avg. RT price).

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Cheapest flight prices on average. 5% potential price decrease ($43 potential savings vs. average RT price).

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Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Tue 9/1611:29 pmSFO - STI

1 stop15h 26mJetBlue

Fri 9/269:55 amSTI - SFO

1 stop16h 47mJetBlue

Deal found 8/14

$495

Thu 11/1310:35 amSFO - STI

1 stop12h 23mJetBlue

Sun 11/164:41 amSTI - SFO

1 stop12h 27mJetBlue

Deal found 8/12

$497

Fri 10/32:05 pmSFO - STI

1 stop17h 49mJetBlue

Fri 10/1012:48 pmSTI - SFO

1 stop15h 11mJetBlue

Deal found 8/13

$504

Fri 10/178:40 pmSFO - STI

1 stop14h 33mJetBlue

Mon 10/273:43 amSTI - SFO

1 stop12h 25mJetBlue

Deal found 8/13

$530

Wed 11/1211:30 amSFO - STI

1 stop11h 28mJetBlue

Sun 11/166:00 amSTI - SFO

1 stop21h 54mJetBlue

Deal found 8/14

$550

Wed 9/1010:35 amSFO - STI

2 stops21h 19mJetBlue

Sat 9/2010:54 amSTI - SFO

1 stop17h 05mJetBlue

Deal found 8/14

$551

Fri 9/51:45 pmSFO - STI

1 stop19h 02mJetBlue

Thu 9/253:30 pmSTI - SFO

1 stop12h 29mJetBlue

Deal found 8/13

$564

Best flights from San Francisco to Santiago de los Caballeros
Discover carefully curated flight deals from San Francisco to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2025.

Tue 9/169:00 pmSFO - STI

1 stop11h 47mJetBlue

Fri 9/269:55 amSTI - SFO

1 stop16h 47mJetBlue

Deal found 8/14

$495

Thu 11/1311:30 amSFO - STI

1 stop11h 28mJetBlue

Sat 11/154:41 amSTI - SFO

1 stop12h 26mJetBlue

Deal found 8/14

$497

Thu 12/117:05 amSFO - STI

1 stop15h 23mJetBlue

Tue 12/1610:46 amSTI - SFO

1 stop17h 28mJetBlue

Deal found 8/14

$497

Thu 11/1310:35 amSFO - STI

1 stop12h 23mJetBlue

Sun 11/164:41 amSTI - SFO

1 stop12h 27mJetBlue

Deal found 8/12

$497

Wed 11/1210:35 amSFO - STI

1 stop12h 23mJetBlue

Sat 11/154:41 amSTI - SFO

1 stop12h 26mJetBlue

Deal found 8/14

$497

Wed 10/226:00 amSFO - STI

1 stop17h 16mJetBlue

Thu 10/309:49 amSTI - SFO

1 stop17h 10mJetBlue

Deal found 8/13

$504

Fri 10/32:05 pmSFO - STI

1 stop17h 49mJetBlue

Fri 10/1012:48 pmSTI - SFO

1 stop15h 11mJetBlue

Deal found 8/13

$504

Fri 10/178:40 pmSFO - STI

1 stop11h 53mJetBlue

Tue 10/289:49 amSTI - SFO

1 stop17h 10mJetBlue

Deal found 8/13

$530

Last-minute flights from San Francisco to Santiago de los Caballeros
Discover last-minute flight deals from San Francisco to Santiago de los Caballeros. Data last updated August 14, 2025 and is based on user searches.

Fri 9/51:45 pmSFO - STI

1 stop19h 02mJetBlue

Thu 9/253:30 pmSTI - SFO

1 stop12h 29mJetBlue

Deal found 8/13

$564

Fri 9/512:15 pmSFO - STI

2 stops21h 12mAmerican Airlines

Thu 9/251:29 pmSTI - SFO

2 stops22h 06mAmerican Airlines

Deal found 8/14

$684

Wed 9/1010:35 amSFO - STI

2 stops21h 19mJetBlue

Sat 9/2010:54 amSTI - SFO

1 stop17h 05mJetBlue

Deal found 8/14

$551

Tue 9/1611:29 pmSFO - STI

1 stop15h 26mJetBlue

Fri 9/269:55 amSTI - SFO

1 stop16h 47mJetBlue

Deal found 8/14

$495

Tue 9/164:37 pmSFO - STI

2 stops16h 50mAmerican Airlines

Fri 9/261:29 pmSTI - SFO

2 stops25h 01mAmerican Airlines

Deal found 8/14

$619

Fri 9/1911:29 pmSFO - STI

1 stop15h 35mJetBlue

Mon 9/292:00 pmSTI - SFO

2 stops36h 42mJetBlue

Deal found 8/14

$641

One-way flights from San Francisco to Santiago de los Caballeros
Search for one-way flight options from San Francisco to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated August 14, 2025.

Sun 10/55:37 pmSFO - STI

3 stops38h 31mMultiple Airlines

Deal found 8/14

$217

Thu 10/25:45 amSFO - STI

3 stops50h 18mMultiple Airlines

Deal found 8/14

$223

Thu 10/211:29 pmSFO - STI

1 stop11h 51mJetBlue

Deal found 8/14

$271

Sun 8/2410:29 pmSFO - STI

3 stops34h 47mMultiple Airlines

Deal found 8/13

$317

Sun 10/56:00 amSFO - STI

1 stop17h 16mJetBlue

Deal found 8/14

$321

Sun 8/244:30 pmSFO - STI

1 stop13h 13mJetBlue

Deal found 8/13

$381

Sat 8/2312:45 amSFO - STI

2 stops17h 03mAmerican Airlines

Deal found 8/13

$522

Sun 10/56:51 pmSFO - STI

2 stops14h 22mAmerican Airlines

Deal found 8/14

$902

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 9/16

9:00 pm-11:47 am

1 stop11h 47m

Santiago de los Caballeros

Fri 9/26

9:55 am-11:42 pm

1 stop16h 47m

$495

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 11/13

11:30 am-2:58 am

1 stop11h 28m

Santiago de los Caballeros

Sat 11/15

4:41 am-1:07 pm

1 stop12h 26m

$497

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 12/11

7:05 am-2:28 am

1 stop15h 23m

Santiago de los Caballeros

Tue 12/16

10:46 am-12:14 am

1 stop17h 28m

$497

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 11/13

10:35 am-2:58 am

1 stop12h 23m

Santiago de los Caballeros

Sun 11/16

4:41 am-1:08 pm

1 stop12h 27m

$497

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Wed 11/12

10:35 am-2:58 am

1 stop12h 23m

Santiago de los Caballeros

Sat 11/15

4:41 am-1:07 pm

1 stop12h 26m

$497

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Wed 10/22

6:00 am-2:16 am

1 stop17h 16m

Santiago de los Caballeros

Thu 10/30

9:49 am-11:59 pm

1 stop17h 10m

$504

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 10/3

2:05 pm-10:54 am

1 stop17h 49m

Santiago de los Caballeros

Fri 10/10

12:48 pm-12:59 am

1 stop15h 11m

$504

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 10/17

8:40 pm-11:33 am

1 stop11h 53m

Santiago de los Caballeros

Tue 10/28

9:49 am-11:59 pm

1 stop17h 10m

$530

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sun 10/5

5:37 pm-11:08 am

3 stops38h 31m

$217

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 10/2

5:45 am-11:03 am

3 stops50h 18m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 16 results

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to STI?

It’s typically best to fly out from San Francisco to Santiago de los Caballeros in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with Delta, American Airlines, and JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,980 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.2

Good

2,913 reviews

Delta

8.0

Very good

7,980 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?
JetBlue, at $463, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros.Alternate airlines to your destination round-trip include Delta and American Airlines. These flights start at 41% lower than the current average price 3 months from now.
Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.
Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$463	Average$604	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$543	Average$634	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$614	Average$838	FlexibilityNo cancel fee	On-time71%

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$217+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Santiago de los Caballeros with Cheapflights

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Cheap flight deals from San Francisco to Santiago de los Caballeros

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Popular in

Cheapest in

Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los CaballerosExplore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

What is the cheapest time of day to fly from SFO to STI?

Find hourly flight availability from San Francisco to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with Delta, American Airlines, and JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?

Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from San Francisco to Santiago de los Caballeros?

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

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Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.