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Santiago de los Caballeros

$259+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — STI
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
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Cheap flight deals from San Francisco to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 16, 2025.

Round-trip from

$451
(JetBlue)

One-way from

$259
(Kiwi.com)

Popular in

February

Cheapest in

July

Average price

$634
From San Francisco to Santiago de los Caballeros
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One-way flight from San Francisco to Santiago de los Caballeros
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Highest demand for flights based on searches. 2% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3112:10 pmSFO - STI
1 stop11h 43mJetBlue
vie. 11/71:07 pmSTI - SFO
1 stop14h 52mJetBlue
Deal found 9/16$451
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/107:45 amSFO - STI
1 stop21h 12mJetBlue
mar. 12/1610:11 amSTI - SFO
1 stop27h 54mJetBlue
Deal found 9/15$468
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/86:00 amSFO - STI
1 stop17h 21mJetBlue
mar. 10/145:50 amSTI - SFO
1 stop30h 35mJetBlue
Deal found 9/14$560
This Expedia deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/86:00 amSFO - STI
1 stop17h 21mJetBlue
lun. 10/275:07 amSTI - SFO
2 stops21h 24mJetBlue
Deal found 9/16$581
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/3012:10 pmSFO - STI
1 stop11h 43mJetBlue
jue. 11/65:00 pmSTI - SFO
1 stop21h 20mJetBlue
Deal found 9/15$611
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/105:00 pmSFO - STI
2 stops18h 32mAmerican Airlines
mar. 12/164:32 pmSTI - SFO
1 stop10h 27mAmerican Airlines
Deal found 9/15$622
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/179:00 pmSFO - STI
1 stop18h 04mJetBlue
lun. 10/275:07 amSTI - SFO
1 stop32h 13mJetBlue
Deal found 9/14$637
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/308:00 amSFO - STI
1 stop25h 13mAmerican Airlines
jue. 11/64:35 pmSTI - SFO
2 stops21h 06mAmerican Airlines
Deal found 9/15$638
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/3111:59 pmSFO - STI
1 stop9h 14mAmerican Airlines
vie. 11/77:00 amSTI - SFO
2 stops12h 03mAmerican Airlines
Deal found 9/16$643
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/83:51 pmSFO - STI
2 stops17h 22mAmerican Airlines
mar. 10/141:14 pmSTI - SFO
1 stop12h 45mAmerican Airlines
Deal found 9/14$664

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

San Francisco

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

vie. 10/31

12:10 pm-2:53 am

1 stop11h 43m

Santiago de los Caballeros

vie. 11/7

1:07 pm-11:59 pm

1 stop14h 52m

$451

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

dom. 3/1

9:35 pm-12:07 pm

1 stop10h 32m

Santiago de los Caballeros

mié. 3/4

4:51 am-1:39 pm

1 stop12h 48m

$451

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

mié. 10/8

6:00 am-2:21 am

1 stop17h 21m

Santiago de los Caballeros

mar. 10/14

5:50 am-9:25 am

1 stop30h 35m

$560

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

mié. 10/8

6:00 am-2:21 am

1 stop17h 21m

Santiago de los Caballeros

lun. 10/27

5:07 am-10:20 am

1 stop32h 13m

$560

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

jue. 1/8

11:15 am-3:51 am

1 stop12h 36m

Santiago de los Caballeros

sáb. 1/17

8:20 am-12:34 am

2 stops20h 14m

$566

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

sáb. 12/6

11:17 pm-5:06 pm

2 stops37h 49m

$259

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

sáb. 12/6

7:45 am-8:57 am

1 stop21h 12m

$331

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

mié. 12/3

11:59 pm-8:33 pm

1 stop16h 34m

$357

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

vie. 10/17

11:25 pm-6:04 pm

1 stop15h 39m

$362

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

vie. 12/5

12:25 am-8:33 pm

2 stops16h 08m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
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Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to STI?

Find hourly flight availability from San Francisco to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 16, 2025.

It’s typically best to fly out from San Francisco to Santiago de los Caballeros in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated septiembre 16, 2025.
Get a feel of what it's like to fly with JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
JetBlue
7.2
Good
2,914 reviews

Entertainment

7.2

Overall

7.2

Food

6.7

Crew

8.0

Comfort

7.6

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.
JetBlue
7.2
Good
2,914 reviews
JetBlue
7.2
Good
2,914 reviews

Entertainment

7.2

Overall

7.2

Food

6.7

Crew

8.0

Comfort

7.6

Boarding

7.4

Reviews

1 / 20
10.0
Excellent

JACK,Sep 2025

JFK - MSY

I liked the professional services of the crew. Keep up the good work.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Francisco to Santiago de los Caballeros?

    Airlines like JetBlue fly from San Francisco to Santiago de los Caballeros in about 11h 43m. The time it takes to get you to your destination can typically vary by up to . San Francisco and Santiago de los Caballeros are separated by a distance of 3336 mi.

  • What is the cheapest airline to fly from San Francisco to Santiago de los Caballeros round-trip?

    JetBlue, at $463, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros.. This flight start at 40% lower than the current average price 3 months from now.

  • Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

  • Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from San Francisco to Santiago de los Caballeros

Discover the top airline that operate flights from San Francisco to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$463Average$604FlexibilityNo cancel feeOn-time62%

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