How long is the flight from San Francisco to Santiago de los Caballeros?

Airlines like JetBlue fly from San Francisco to Santiago de los Caballeros in about 12h 05m. The time it takes to get you to your destination can typically vary by up to . San Francisco and Santiago de los Caballeros are separated by a distance of 3336 mi.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Most accurate provider : When it comes to deals on San Francisco-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Francisco-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from San Francisco to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$232+ Flights from San Francisco to Santiago de los Caballeros

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1. Tell us where you want to go

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Cheap flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Wed 12/1011:28 amSFO - STI

1 stop10h 45mJetBlue

Sun 12/1411:15 amSTI - SFO

1 stop16h 44mJetBlue

Deal found 12/6

$783

Best flights from San Francisco to Santiago de los Caballeros
Discover carefully curated flight deals from San Francisco to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 8, 2025.

Thu 1/2910:50 amSFO - STI

1 stop12h 05mJetBlue

Tue 2/105:10 amSTI - SFO

1 stop18h 05mJetBlue

Deal found 12/7

$420

Thu 1/295:05 pmSFO - STI

2 stops18h 27mAmerican Airlines

Tue 2/106:00 amSTI - SFO

2 stops14h 01mAmerican Airlines

Deal found 12/7

$622

Sun 5/38:30 pmSFO - STI

1 stop13h 52mJetBlue

Wed 5/69:00 amSTI - SFO

1 stop12h 51mJetBlue

Deal found 12/5

$420

Tue 3/312:55 pmSFO - STI

1 stop10h 49mJetBlue

Thu 3/127:05 amSTI - SFO

1 stop15h 24mJetBlue

Deal found 12/6

$434

Tue 1/2011:59 pmSFO - STI

1 stop30h 38mJetBlue

Sun 2/16:01 amSTI - SFO

1 stop12h 11mJetBlue

Deal found 12/8

$437

Thu 6/41:30 pmSFO - STI

1 stop17h 30mJetBlue

Sun 6/711:10 amSTI - SFO

1 stop13h 31mJetBlue

Deal found 12/6

$496

Wed 3/48:00 amSFO - STI

1 stop14h 44mJetBlue

Sun 3/157:05 amSTI - SFO

1 stop15h 24mJetBlue

Deal found 12/6

$523

Last-minute flights from San Francisco to Santiago de los Caballeros
Discover last-minute flight deals from San Francisco to Santiago de los Caballeros. Data last updated December 8, 2025 and is based on user searches.

Wed 12/1011:28 amSFO - STI

1 stop10h 45mJetBlue

Sun 12/1411:15 amSTI - SFO

1 stop16h 44mJetBlue

Deal found 12/6

$783

Thu 1/155:05 pmSFO - STI

2 stops18h 27mAmerican Airlines

Mon 1/266:00 amSTI - SFO

2 stops14h 01mAmerican Airlines

Deal found 12/7

$642

Tue 1/2011:59 pmSFO - STI

1 stop30h 38mJetBlue

Sun 2/16:01 amSTI - SFO

1 stop12h 11mJetBlue

Deal found 12/8

$437

Tue 1/2010:59 pmSFO - STI

1 stop12h 33mAmerican Airlines

Sun 2/16:00 amSTI - SFO

2 stops17h 12mAmerican Airlines

Deal found 12/8

$647

Thu 1/2910:50 amSFO - STI

1 stop12h 05mJetBlue

Tue 2/105:10 amSTI - SFO

1 stop18h 05mJetBlue

Deal found 12/7

$420

Thu 1/295:05 pmSFO - STI

2 stops18h 27mAmerican Airlines

Tue 2/106:00 amSTI - SFO

2 stops14h 01mAmerican Airlines

Deal found 12/7

$622

One-way flights from San Francisco to Santiago de los Caballeros
Search for one-way flight options from San Francisco to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated December 8, 2025.

Sat 5/236:55 amSFO - STI

1 stop17h 15mJetBlue

Deal found 12/6

$232

Fri 12/2611:20 pmSFO - STI

3 stops23h 22mMultiple Airlines

Deal found 12/7

$293

Thu 12/2511:20 pmSFO - STI

3 stops47h 22mMultiple Airlines

Deal found 12/7

$410

Wed 12/244:06 pmSFO - STI

2 stops30h 36mMultiple Airlines

Deal found 12/7

$493

Wed 12/241:15 pmSFO - STI

1 stop11h 35mJetBlue

Deal found 12/7

$522

Sat 5/231:25 pmSFO - STI

3 stops44h 36mMultiple Airlines

Deal found 12/6

$813

Find flight deals from San Francisco to Santiago de los Caballeros

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$420 (Expedia)
One-way from	$232 (Priceline)
Popular in	December
Cheapest in	July
Average price	$1,287

Provider with most accurate pricing for San Francisco-Santiago de los Caballeros flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Francisco-Santiago de los Caballeros flights.

Search Deals

From San Francisco to Santiago de los Caballeros

Search Deals

One-way flight from San Francisco to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 13% potential increase in price ($125 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($50 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 1/29

10:50 am-2:55 am

1 stop12h 05m

Santiago de los Caballeros

Tue 2/10

5:10 am-7:15 pm

1 stop18h 05m

$420

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sun 5/3

8:30 pm-1:22 pm

1 stop13h 52m

Santiago de los Caballeros

Wed 5/6

9:00 am-6:51 pm

1 stop12h 51m

$420

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 3/3

12:55 pm-3:44 am

1 stop10h 49m

Santiago de los Caballeros

Thu 3/12

7:05 am-7:29 pm

1 stop15h 24m

$434

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 1/20

11:59 pm-10:37 am

1 stop30h 38m

Santiago de los Caballeros

Sun 2/1

6:01 am-2:12 pm

1 stop12h 11m

$437

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 6/4

1:30 pm-10:00 am

1 stop17h 30m

Santiago de los Caballeros

Sun 6/7

11:10 am-9:41 pm

1 stop13h 31m

$496

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Wed 3/4

8:00 am-2:44 am

1 stop14h 44m

Santiago de los Caballeros

Sun 3/15

7:05 am-7:29 pm

1 stop15h 24m

$523

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 1/29

5:05 pm-3:32 pm

2 stops18h 27m

Santiago de los Caballeros

Tue 2/10

6:00 am-4:01 pm

2 stops14h 01m

$622

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Fri 12/26

11:20 pm-2:42 am

3 stops23h 22m

$293

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Sat 5/23

6:00 am-11:59 pm

2 stops14h 59m

$339

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 12/25

11:20 pm-2:42 am

3 stops47h 22m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Showing 1-10 of 15 results

Compare providers for flights from San Francisco to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago de los Caballeros in December.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Francisco-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Francisco-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Francisco-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, July is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $281). Flying from San Francisco to Santiago de los Caballeros in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to STI?

It’s typically best to fly out from San Francisco to Santiago de los Caballeros in the afternoon. Doing so could potentially save you 32% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with American Airlines and JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.2

Good

11,044 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

American Airlines

7.2

Good

11,044 reviews

American Airlines

7.2

Good

11,044 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

JetBlue

7.2

Good

2,896 reviews

American Airlines

7.2

Good

11,044 reviews

Reviews

1 / 20

10.0

Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

How long is the flight from San Francisco to Santiago de los Caballeros?
Airlines like JetBlue fly from San Francisco to Santiago de los Caballeros in about 12h 05m. The time it takes to get you to your destination can typically vary by up to . San Francisco and Santiago de los Caballeros are separated by a distance of 3336 mi.
What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?
JetBlue, at $473, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros. An alternate airline flying to your destination would be American Airlines. These flights start at 39% lower than the current average price 3 months from now.
Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.
Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?
Currently, July is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $281). Flying from San Francisco to Santiago de los Caballeros in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from San Francisco to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$473	Average$634	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$614	Average$1,287	FlexibilityNo cancel fee	On-time71%

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$232+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los CaballerosExplore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

Find flight deals from San Francisco to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Compare providers for flights from San Francisco to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Santiago de los Caballeros in December.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

What is the cheapest time of day to fly from SFO to STI?

Reviews of airlines servicing Santiago de los Caballeros

Get a feel of what it's like to fly with American Airlines and JetBlue from San Francisco to Santiago de los Caballeros by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from San Francisco to Santiago de los Caballeros?

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?

Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from San Francisco to Santiago de los Caballeros?

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from San Francisco to Santiago de los Caballeros

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Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.