What is the cheapest day to fly from San Francisco to Santiago de los Caballeros?

Travelers seeking maximum savings on their San Francisco to Santiago de los Caballeros flight should consider departing on Monday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from San Francisco to Santiago de los Caballeros?

When booking a flight from San Francisco to Santiago de los Caballeros, you may want to consider flying on American Airlines, JetBlue or Delta as they are the most popular for this route.

What is the cheapest day to fly round-trip from San Francisco to Santiago de los Caballeros?

Leaving on a Sunday is a viable option for saving on travel. Heavily demanded days of the week can typically drive up the prices you see. Booking your travel for a less competitive day can save up to 77% on the overall cost on flights from San Francisco to Santiago de los Caballeros.

What is the cheapest month to fly from San Francisco to Santiago de los Caballeros?

January can be a great time to fly to Santiago de los Caballeros from San Francisco with a flight ticket averaging about $811. Cheapflights users have found deals in the month of January for as cheap as $480. The most expensive prices can be found in the month of February.

How can I find direct flights from San Francisco to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$495+ Flights from San Francisco to Santiago de los Caballeros

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Cheap flight deals from San Francisco to Santiago de los Caballeros

Round-trip from	$495 (JetBlue)
Popular in	February
Cheapest in	January
Average price	$838

From San Francisco to Santiago de los Caballeros

Search Deals

High demand for flights, 1% potential price rise

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Cheapest flight prices on average. 4% potential price decrease ($37 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in June 2025

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Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Thu 11/66:00 amSFO - STI

1 stop10h 14mJetBlue

Mon 11/172:10 pmSTI - SFO

1 stop14h 24mJetBlue

Deal found 6/12

$495

Tue 9/1610:45 pmSFO - STI

1 stop10h 43mDelta

Fri 9/266:20 amSTI - SFO

1 stop15h 34mDelta

Deal found 6/10

$615

Tue 9/1612:15 pmSFO - STI

2 stops21h 12mAmerican Airlines

Fri 9/261:29 pmSTI - SFO

1 stop12h 22mAmerican Airlines

Deal found 6/11

$619

Tue 9/162:05 pmSFO - STI

3 stops42h 19mMultiple Airlines

Fri 9/2612:19 pmSTI - SFO

3 stops26h 02mMultiple Airlines

Deal found 6/10

$648

Best flights from San Francisco to Santiago de los Caballeros
Discover carefully curated flight deals from San Francisco to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 12, 2025.

Thu 11/66:00 amSFO - STI

1 stop10h 14mJetBlue

Mon 11/172:10 pmSTI - SFO

1 stop14h 24mJetBlue

Deal found 6/12

$495

Tue 9/1610:45 pmSFO - STI

1 stop10h 43mDelta

Fri 9/266:20 amSTI - SFO

1 stop15h 34mDelta

Deal found 6/10

$615

Tue 9/162:17 pmSFO - STI

2 stops19h 10mAmerican Airlines

Fri 9/261:29 pmSTI - SFO

2 stops12h 46mAmerican Airlines

Deal found 6/11

$619

Tue 9/162:05 pmSFO - STI

3 stops42h 19mMultiple Airlines

Fri 9/2612:19 pmSTI - SFO

3 stops26h 02mMultiple Airlines

Deal found 6/10

$648

Last-minute flights from San Francisco to Santiago de los Caballeros
Discover last-minute flight deals from San Francisco to Santiago de los Caballeros. Data last updated June 12, 2025 and is based on user searches.

Thu 6/1211:59 pmSFO - STI

3 stops31h 30mMultiple Airlines

Tue 6/2411:29 amSTI - SFO

2 stops27h 10mMultiple Airlines

Deal found 6/10

$1,406

Sat 7/126:00 amSFO - STI

1 stop15h 52mJetBlue

Mon 7/2110:38 pmSTI - SFO

1 stop14h 07mJetBlue

Deal found 6/11

$792

Sat 7/126:45 pmSFO - STI

2 stops14h 44mAmerican Airlines

Mon 7/217:04 amSTI - SFO

1 stop14h 43mAmerican Airlines

Deal found 6/10

$884

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Thu 11/6

9:35 pm-12:07 pm

1 stop10h 32m

Santiago de los Caballeros

Sun 11/16

2:15 am-11:09 am

1 stop12h 54m

$495

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 9/16

10:45 pm-12:28 pm

1 stop10h 43m

Santiago de los Caballeros

Fri 9/26

6:20 am-6:54 pm

1 stop15h 34m

$615

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 9/16

12:15 pm-12:27 pm

2 stops21h 12m

Santiago de los Caballeros

Fri 9/26

1:29 pm-10:51 pm

1 stop12h 22m

$619

San FranciscoSantiago de los Caballeros

SFO - STI

SFOSTI

San Francisco

Tue 9/16

2:05 pm-11:24 am

3 stops42h 19m

Santiago de los Caballeros

Fri 9/26

12:19 pm-11:21 am

3 stops26h 02m

$648

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to STI?

It’s typically best to fly out from San Francisco to Santiago de los Caballeros in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying in the evening, which is usually more expensive.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,946 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,925 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,946 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?
JetBlue, at $495, was found to be the cheapest airline from San Francisco to Santiago de los Caballeros.Alternate airlines to your destination round-trip include Delta and American Airlines. These flights start at 38% lower than the current average price 3 months from now.
Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on San Francisco to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Francisco to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Santiago de los Caballeros.
Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from San Francisco to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from San Francisco to Santiago de los Caballeros (average of $347). Flying from San Francisco to Santiago de los Caballeros in July is currently the most expensive (average of $630). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$463	Average$634	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$543	Average$643	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$624	Average$838	FlexibilityNo cancel fee	On-time71%

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$495+ Cheap flights from San Francisco (SFO) to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Francisco to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from San Francisco to Santiago de los Caballeros

Round-trip from

Popular in

Cheapest in

Average price

Find flight deals from San Francisco to Santiago de los Caballeros

Cheapest flights from San Francisco to Santiago de los CaballerosExplore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Francisco to Santiago de los Caballeros that are best for you.

Best time to book a flight from San Francisco to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from San Francisco with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Santiago de los Caballeros

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

What is the cheapest time of day to fly from SFO to STI?

Find hourly flight availability from San Francisco to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from San Francisco to Santiago de los Caballeros round-trip?

Can I find deals for flights from San Francisco to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from San Francisco to Santiago de los Caballeros?

Can I find deals for business class flights from San Francisco to Santiago de los Caballeros?

What is the cheapest month to book a flight from San Francisco to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from San Francisco to Santiago de los Caballeros

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Travel Smart

Cheapest flights from San Francisco to Santiago de los Caballeros
Explore the most affordable flight options available from San Francisco to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.