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$306+ Cheap flights from Jacksonville (JAX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — SCL
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
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Cheap flight deals from Jacksonville to Santiago

Cheapest flights from Jacksonville to Santiago
Explore the most affordable flight options available from Jacksonville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This Ovago deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/87:30 am
JAX
-
SCL
1 stop23h 45m
LATAM Airlines
Wed 7/158:40 pm
SCL
-
JAX
1 stop13h 41m
LATAM Airlines
Deal found 2/5$692
This KAYAK deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:29 am
JAX
-
SCL
1 stop19h 46m
LATAM Airlines
Wed 7/1511:05 pm
SCL
-
JAX
2 stops24h 57m
LATAM Airlines
Deal found 2/6$725
This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:33 pm
JAX
-
SCL
1 stop13h 07m
Delta
Tue 3/2410:40 pm
SCL
-
JAX
1 stop16h 05m
Delta
Deal found 2/7$783
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:24 am
JAX
-
SCL
2 stops19h 26m
United Airlines
Mon 3/169:45 pm
SCL
-
JAX
2 stops24h 47m
United Airlines
Deal found 2/7$788
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:04 pm
JAX
-
SCL
1 stop33h 51m
Delta
Wed 3/2510:25 pm
SCL
-
JAX
1 stop20h 08m
Delta
Deal found 2/5$792
This Ovago deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/71:20 pm
JAX
-
SCL
1 stop17h 55m
LATAM Airlines
Fri 8/148:40 pm
SCL
-
JAX
1 stop22h 18m
LATAM Airlines
Deal found 2/4$796
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/185:22 pm
JAX
-
SCL
1 stop13h 28m
United Airlines
Tue 3/249:45 pm
SCL
-
JAX
1 stop19h 31m
United Airlines
Deal found 2/6$797
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
JAX
-
SCL
2 stops48h 50m
United Airlines
Mon 3/239:45 pm
SCL
-
JAX
3 stops23h 19m
United Airlines
Deal found 2/5$805

Find flight deals from Jacksonville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$692
(Ovago)

One-way from

$306
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$973
Provider with most accurate pricing for Jacksonville-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Jacksonville-Santiago Arturo Merino Benitez flights.
Search Deals
From Jacksonville to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Jacksonville to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($124 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from Jacksonville to Santiago that are best for you.

Fly from

Jacksonville

Fly to

Santiago

Route

Depart

Return

Price

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 3/16

3:59 pm-7:40 am

1 stop14h 41m

Santiago Arturo Merino Benitez

Wed 3/25

10:40 pm-3:05 pm

1 stop17h 25m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 3/16

5:22 pm-7:50 am

1 stop13h 28m

Santiago Arturo Merino Benitez

Tue 3/24

9:45 pm-10:31 am

1 stop13h 46m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 3/16

5:22 pm-7:50 am

1 stop13h 28m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-4:16 pm

1 stop19h 31m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 3/12

11:58 am-5:55 am

1 stop16h 57m

Santiago Arturo Merino Benitez

Tue 3/24

10:40 pm-1:45 pm

1 stop16h 05m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Mon 3/16

5:22 pm-7:50 am

1 stop13h 28m

Santiago Arturo Merino Benitez

Thu 3/26

9:45 pm-4:16 pm

1 stop19h 31m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 3/12

2:25 pm-5:55 am

1 stop14h 30m

Santiago Arturo Merino Benitez

Thu 3/26

6:30 pm-10:18 am

2 stops16h 48m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 3/17

3:59 pm-7:40 am

1 stop14h 41m

Santiago Arturo Merino Benitez

Thu 3/26

10:30 pm-1:45 pm

1 stop16h 15m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 3/12

2:25 pm-5:55 am

1 stop14h 30m

Santiago Arturo Merino Benitez

Wed 3/25

10:25 pm-2:52 pm

1 stop17h 27m

$783

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sun 4/26

6:08 pm-9:05 pm

3 stops26h 57m

$306

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sun 4/26

7:59 pm-6:00 am

2 stops34h 01m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/7

Showing 1-10 of 12 results
1
2

Compare providers for flights from Jacksonville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Santiago in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Jacksonville-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Jacksonville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated February 9, 2026.
Get a feel of what it's like to fly with American Airlines from Jacksonville to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,254 reviews

Comfort

7.2

Food

6.4

Entertainment

6.9

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
American Airlines
7.2
Good
11,254 reviews
American Airlines
7.2
Good
11,254 reviews

Comfort

7.2

Food

6.4

Entertainment

6.9

Boarding

7.5

Crew

8.0

Overall

7.2

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santiago?

    There are many flights that can get you from Jacksonville to Santiago in 13h 28m. Fly via Delta or United Airlines to get the fastest option. Jacksonville and Santiago are separated by a distance of 4468 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Jacksonville to Santiago round-trip?

    Our cheapest airline available from Jacksonville to Santiago is American Airlines. Our recent data shows that you can find tickets from as low as $703 on this airline. American Airlines is priced at 26% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Jacksonville to Santiago that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago.

  • Can I find deals for business class flights from Jacksonville to Santiago?

    Yes. Cheapflights offers flight deals from Jacksonville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Jacksonville to Santiago

Discover the top airline that operate flights from Jacksonville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$703Average$840FlexibilityNo cancel feeOn-time71%

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