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$347+ Cheap flights from Jacksonville (JAX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — SCL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Jacksonville to Santiago

Cheapest flights from Jacksonville to Santiago
Explore the most affordable flight options available from Jacksonville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:42 amJAX - SCL
1 stop20h 43mAmerican Airlines
Thu 2/1211:15 pmSCL - JAX
1 stop18h 39mAmerican Airlines
Deal found 12/3$664
This LATAM Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:00 amJAX - SCL
2 stops22h 00mLATAM Airlines
Thu 2/1211:10 pmSCL - JAX
1 stop13h 11mLATAM Airlines
Deal found 12/3$669
This Orbitz deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:38 amJAX - SCL
2 stops39h 57mLATAM Airlines
Mon 2/236:30 pmSCL - JAX
2 stops17h 51mLATAM Airlines
Deal found 12/3$705
This Expedia deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:41 pmJAX - SCL
2 stops34h 19mLATAM Airlines
Fri 1/236:40 amSCL - JAX
2 stops19h 18mLATAM Airlines
Deal found 12/3$745
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:55 pmJAX - SCL
1 stop13h 55mUnited Airlines
Fri 1/2310:45 pmSCL - JAX
1 stop13h 57mUnited Airlines
Deal found 12/3$839
This American Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:33 pmJAX - SCL
1 stop10h 52mAmerican Airlines
Mon 2/2311:15 pmSCL - JAX
1 stop18h 39mAmerican Airlines
Deal found 12/3$884

Find flight deals from Jacksonville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$664
(American Airlines)

One-way from

$347
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$1,096
Provider with most accurate pricing for Jacksonville-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Jacksonville-Santiago Arturo Merino Benitez flights.
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From Jacksonville to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Jacksonville to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago that are best for you.

Fly from

Jacksonville

Fly to

Santiago

Route

Depart

Return

Price

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 12/24

10:42 am-9:25 am

1 stop20h 43m

Santiago Arturo Merino Benitez

Thu 2/12

11:15 pm-3:54 pm

1 stop18h 39m

$664

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 12/24

1:44 pm-2:30 pm

3 stops22h 46m

Santiago Arturo Merino Benitez

Thu 2/12

8:50 am-10:58 pm

2 stops16h 08m

$669

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 12/23

11:38 am-5:35 am

2 stops39h 57m

Santiago Arturo Merino Benitez

Mon 2/23

6:30 pm-10:21 am

2 stops17h 51m

$705

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 12/23

6:41 pm-7:00 am

2 stops34h 19m

Santiago Arturo Merino Benitez

Fri 1/23

6:40 am-11:58 pm

2 stops19h 18m

$745

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 12/23

4:55 pm-8:50 am

1 stop13h 55m

Santiago Arturo Merino Benitez

Fri 1/23

10:45 pm-10:42 am

1 stop13h 57m

$839

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 12/23

8:33 pm-9:25 am

1 stop10h 52m

Santiago Arturo Merino Benitez

Mon 2/23

11:15 pm-3:54 pm

1 stop18h 39m

$884

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 3/11

8:12 am-3:20 pm

3 stops30h 08m

$347

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 3/10

11:37 am-3:20 pm

3 stops50h 43m

$352

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sun 2/15

5:51 pm-10:15 pm

3 stops26h 24m

$386

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 3/12

4:45 pm-3:20 pm

3 stops45h 35m

$446

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 15 results
1
2

Compare providers for flights from Jacksonville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Jacksonville-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Jacksonville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago

What is the cheapest time of day to fly from JAX to SCL?

Find hourly flight availability from Jacksonville to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 24% on flights from Jacksonville to Santiago by exploring options for tickets in the afternoon.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 4, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Jacksonville to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,011 reviews

Comfort

7.9

Overall

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santiago?

    There are many flights that can get you from Jacksonville to Santiago in 20h 43m. Fly via American Airlines or LATAM Airlines to get the fastest option. Jacksonville and Santiago are separated by a distance of 4468 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Jacksonville to Santiago round-trip?

    Our cheapest airline available from Jacksonville to Santiago is Delta. Our recent data shows that you can find tickets from as low as $683 on this airline. An additional option worth looking into is American Airlines, starting at $703. Delta is priced at 28% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Jacksonville to Santiago that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago.

  • Can I find deals for business class flights from Jacksonville to Santiago?

    Yes. Cheapflights offers flight deals from Jacksonville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Jacksonville to Santiago

Discover the top 2 airlines that operate flights from Jacksonville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$683Average$1,028FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$703Average$863FlexibilityNo cancel feeOn-time71%

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