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$543+ Cheap flights from Jacksonville (JAX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
JAX — SCL
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Jacksonville to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Jacksonville (JAX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$664
(LATAM Airlines)

One-way from

$543
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$843
Provider with most accurate pricing for Jacksonville-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Jacksonville-Santiago Arturo Merino Benitez flights.
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From Jacksonville to Santiago Arturo Merino Benitez
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One-way flight from Jacksonville to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($91 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Jacksonville to Santiago

Cheapest flights from Jacksonville to Santiago
Explore the most affordable flight options available from Jacksonville to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This LATAM Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:12 amJAX - SCL
1 stop22h 28mLATAM Airlines
Wed 12/1011:10 pmSCL - JAX
1 stop27h 01mLATAM Airlines
Deal found 11/20$663
This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:55 amJAX - SCL
2 stops17h 05mDelta
Wed 12/1011:25 pmSCL - JAX
2 stops17h 38mDelta
Deal found 11/20$669
This KAYAK deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/84:08 pmJAX - SCL
1 stop13h 32mLATAM Airlines
Sat 12/1310:25 pmSCL - JAX
2 stops26h 39mLATAM Airlines
Deal found 11/19$704
This KAYAK deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/811:47 amJAX - SCL
2 stops15h 48mLATAM Airlines
Sun 12/148:50 amSCL - JAX
2 stops17h 21mLATAM Airlines
Deal found 11/18$709
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/95:35 pmJAX - SCL
1 stop12h 05mDelta
Mon 12/299:30 pmSCL - JAX
1 stop13h 16mDelta
Deal found 11/18$716
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:05 amJAX - SCL
2 stops21h 55mDelta
Mon 12/299:30 pmSCL - JAX
1 stop13h 16mDelta
Deal found 11/18$721
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:40 pmJAX - SCL
1 stop15h 10mUnited Airlines
Sun 12/1410:45 pmSCL - JAX
1 stop18h 51mUnited Airlines
Deal found 11/18$744
This KAYAK deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:08 pmJAX - SCL
3 stops27h 27mLATAM Airlines
Sun 12/2811:10 pmSCL - JAX
1 stop13h 33mLATAM Airlines
Deal found 11/18$749
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:29 pmJAX - SCL
1 stop35h 26mDelta
Sun 12/2811:10 pmSCL - JAX
1 stop21h 44mDelta
Deal found 11/18$753
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:45 amJAX - SCL
2 stops18h 50mDelta
Sun 12/2811:10 pmSCL - JAX
1 stop21h 44mDelta
Deal found 11/18$756
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:45 amJAX - SCL
2 stops19h 10mDelta
Mon 12/299:30 pmSCL - JAX
1 stop13h 16mDelta
Deal found 11/18$761
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:15 pmJAX - SCL
1 stop36h 40mDelta
Mon 12/299:30 pmSCL - JAX
1 stop13h 16mDelta
Deal found 11/18$765

Cheapflights Fare Finder

 
Customize your flight search to find flights from Jacksonville to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Jacksonville to Santiago that are best for you.

Fly from

Jacksonville

Fly to

Santiago

Route

Depart

Return

Price

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 12/10

11:10 am-6:55 am

1 stop17h 45m

Santiago Arturo Merino Benitez

Mon 12/29

9:30 pm-8:46 am

1 stop13h 16m

$716

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sun 1/11

5:39 pm-9:35 pm

3 stops25h 56m

Santiago Arturo Merino Benitez

Sat 1/17

10:15 pm-11:58 pm

2 stops27h 43m

$739

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sun 12/7

3:40 pm-8:50 am

1 stop15h 10m

Santiago Arturo Merino Benitez

Sun 12/14

10:45 pm-3:36 pm

1 stop18h 51m

$744

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Thu 12/11

4:08 pm-6:10 am

1 stop12h 02m

Santiago Arturo Merino Benitez

Mon 12/29

9:30 pm-8:46 am

1 stop13h 16m

$768

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Tue 12/23

7:59 pm-7:40 am

1 stop33h 41m

Santiago Arturo Merino Benitez

Mon 12/29

9:30 pm-8:46 am

1 stop13h 16m

$829

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Fri 12/12

9:45 am-6:35 am

2 stops18h 50m

Santiago Arturo Merino Benitez

Mon 12/29

9:30 pm-8:46 am

1 stop13h 16m

$836

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 12/24

4:55 pm-8:50 am

1 stop13h 55m

Santiago Arturo Merino Benitez

Mon 12/29

10:45 pm-11:30 pm

1 stop26h 45m

$864

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Fri 12/26

7:59 pm-6:10 am

1 stop32h 11m

Santiago Arturo Merino Benitez

Mon 12/29

9:30 pm-8:46 am

1 stop13h 16m

$869

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Wed 12/10

3:40 pm-8:50 am

1 stop15h 10m

Santiago Arturo Merino Benitez

Tue 12/30

10:45 pm-11:30 pm

1 stop26h 45m

$886

JacksonvilleSantiago

JAX - SCL

JAXSCL

Jacksonville

Sat 12/20

8:55 am-3:20 pm

3 stops52h 25m

$543

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 11 results
1
2

Compare providers for flights from Jacksonville to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Jacksonville to Santiago in November.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Jacksonville-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Jacksonville-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Jacksonville-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Jacksonville-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Jacksonville-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Jacksonville to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Jacksonville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Jacksonville to Santiago

What is the cheapest time of day to fly from JAX to SCL?

Find hourly flight availability from Jacksonville to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 24% on flights from Jacksonville to Santiago by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Jacksonville to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Jacksonville to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,047 reviews
Delta
7.9
Good
8,002 reviews

Boarding

8.1

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Jacksonville to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Jacksonville to Santiago?

    There are many flights that can get you from Jacksonville to Santiago in 15h 10m. Fly via Delta, LATAM Airlines, or United Airlines to get the fastest option. Jacksonville and Santiago are separated by a distance of 4468 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Jacksonville to Santiago round-trip?

    Our cheapest airline available from Jacksonville to Santiago is Delta. Our recent data shows that you can find tickets from as low as $683 on this airline. An additional option worth looking into is American Airlines, starting at $703. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Jacksonville to Santiago that include hotel bookings?

    Yes. In addition to deals on Jacksonville to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Jacksonville to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Jacksonville to Santiago.

  • Can I find deals for business class flights from Jacksonville to Santiago?

    Yes. Cheapflights offers flight deals from Jacksonville to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Jacksonville to Santiago

Discover the top 2 airlines that operate flights from Jacksonville to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$683Average$942FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$703Average$863FlexibilityNo cancel feeOn-time71%

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