Santa Cruz de la Sierra

$409+ Cheap flights from Missouri to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — VVI
dic. 4 — dic. 111
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Cheap flight deals from Missouri to Santa Cruz de la Sierra

Keep the following information in mind while searching for Missouri to Santa Cruz de la Sierra flight deals. Data was last updated noviembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$765
(United Airlines)

One-way from

$409
(United Airlines)
Provider with most accurate pricing for Lambert-St Louis-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Provider most trusted by Cheapflights users for Lambert-St Louis-Santa Cruz de la Sierra Viru Viru Intl flights.
From Missouri to Santa Cruz de la Sierra Viru Viru Intl
One-way flight from Missouri to Santa Cruz de la Sierra Viru Viru Intl

Find flight deals from Missouri to Santa Cruz de la Sierra

Best flights from Missouri to Santa Cruz de la Sierra
Discover carefully curated flight deals from Missouri to Santa Cruz de la Sierra that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated noviembre 4, 2025.

This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/56:15 amSTL - VVI
2 stops20h 29mUnited Airlines
mar. 4/711:44 amVVI - STL
2 stops33h 37mUnited Airlines
Deal found 11/2$765
This Copa Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/1411:40 amMCI - VVI
2 stops39h 04mCopa Airlines
vie. 4/171:15 amVVI - MCI
2 stops19h 16mCopa Airlines
Deal found 11/2$1,586
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/146:10 amMCI - VVI
2 stops15h 40mUnited Airlines
sáb. 4/1811:44 amVVI - MCI
2 stops34h 51mUnited Airlines
Deal found 11/2$855

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
Use the filters below to find and compare flights from Missouri to Santa Cruz de la Sierra that are best for you.

Fly from

Missouri

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

St. LouisSanta Cruz de la Sierra

STL - VVI

STLVVI

Lambert-St Louis

dom. 4/5

6:15 am-3:44 am

2 stops20h 29m

Santa Cruz de la Sierra Viru Viru Intl

mar. 4/7

11:44 am-8:21 pm

2 stops33h 37m

$765

Kansas CitySanta Cruz de la Sierra

MCI - VVI

MCIVVI

Kansas City

mar. 4/14

6:10 am-10:50 pm

2 stops15h 40m

Santa Cruz de la Sierra Viru Viru Intl

sáb. 4/18

11:44 am-9:35 pm

2 stops34h 51m

$855

Kansas CitySanta Cruz de la Sierra

MCI - VVI

MCIVVI

Kansas City

mar. 4/14

11:40 am-3:44 am

2 stops39h 04m

Santa Cruz de la Sierra Viru Viru Intl

vie. 4/17

1:15 am-7:31 pm

2 stops19h 16m

$1,586

St. LouisSanta Cruz de la Sierra

STL - VVI

STLVVI

Lambert-St Louis

vie. 4/3

6:15 am-3:44 am

2 stops20h 29m

$409

St. LouisSanta Cruz de la Sierra

STL - VVI

STLVVI

Lambert-St Louis

vie. 4/3

4:00 pm-10:29 am

3 stops41h 29m

$1,215

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Missouri to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santa Cruz de la Sierra from Missouri?

    Most people fly into Santa Cruz de la Sierra Viru Viru Intl (VVI) if they book a flight to Santa Cruz de la Sierra from Missouri. Viru Viru Intl is conveniently located just 11.5 mi from Santa Cruz de la Sierra’s city center.

  • How long is the flight from Missouri to Santa Cruz de la Sierra?

    Departing from Missouri to Santa Cruz de la Sierra will take you 20h 29m. Missouri and Santa Cruz de la Sierra are separated by a distance of 4274 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Missouri to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Missouri to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Missouri to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Missouri to Santa Cruz de la Sierra

Discover the top airline that operate flights from Missouri to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$653Average$909FlexibilityNo cancel feeOn-time69%

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