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Santa Cruz de la Sierra

$270+ Cheap flights from Indiana to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — VVI
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheap flight deals from Indiana to Santa Cruz de la Sierra

Keep the following information in mind while searching for Indiana to Santa Cruz de la Sierra flight deals. Data was last updated June 30, 2025.

Round-trip from

$587
(Copa Airlines)

One-way from

$270
(Copa Airlines)
From Indiana to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Indiana to Santa Cruz de la Sierra Viru Viru Intl
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Find flight deals from Indiana to Santa Cruz de la Sierra

Cheapest flights from Indiana to Santa Cruz de la Sierra
Explore the most affordable flight options available from Indiana to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/77:55 amORD - VVI
1 stop13h 24mCopa Airlines
Tue 8/191:09 amVVI - ORD
1 stop13h 32mCopa Airlines
Deal found 6/28$587
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/79:07 pmORD - VVI
2 stops48h 12mUnited Airlines
Tue 8/191:09 amVVI - ORD
2 stops31h 44mUnited Airlines
Deal found 6/28$594
This United deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:00 amORD - VVI
2 stops38h 19mMultiple Airlines
Sat 8/302:55 amVVI - ORD
2 stops20h 46mMultiple Airlines
Deal found 6/29$668
This Avianca deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1610:54 amORD - VVI
2 stops13h 56mAvianca
Fri 9/262:55 amVVI - ORD
1 stop11h 20mAvianca
Deal found 6/29$703
This Trip.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/275:25 pmCVG - VVI
2 stops56h 25mMultiple Airlines
Wed 7/302:55 amVVI - CVG
2 stops20h 59mMultiple Airlines
Deal found 6/30$750
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/259:40 amSDF - VVI
2 stops36h 04mUnited Airlines
Mon 10/2712:55 amVVI - SDF
2 stops18h 40mUnited Airlines
Deal found 6/29$761
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amIND - VVI
2 stops15h 44mUnited Airlines
Sat 11/812:55 amVVI - IND
2 stops20h 01mUnited Airlines
Deal found 6/30$799
This lastminute.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/276:00 amCVG - VVI
2 stops40h 19mCopa Airlines
Thu 7/3112:15 pmVVI - CVG
2 stops30h 47mCopa Airlines
Deal found 6/30$1,135
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/237:30 amSBN - VVI
2 stops38h 49mUnited Airlines
Wed 8/201:09 amVVI - SBN
2 stops20h 31mUnited Airlines
Deal found 6/28$1,321
This Avianca deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/310:25 amDAY - VVI
2 stops15h 25mAvianca
Mon 10/62:55 amVVI - DAY
2 stops16h 04mAvianca
Deal found 6/27$1,529
This Justfly.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:48 pmIND - VVI
2 stops37h 47mLATAM Airlines
Sat 12/2011:15 amVVI - IND
2 stops31h 02mLATAM Airlines
Deal found 6/29$1,530
This LATAM Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:00 amSDF - VVI
2 stops21h 35mLATAM Airlines
Tue 10/285:25 amVVI - SDF
2 stops18h 31mLATAM Airlines
Deal found 6/27$2,421

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Indiana to Santa Cruz de la Sierra that are best for you.

Fly from

Indiana

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 8/7

7:55 am-10:19 pm

1 stop13h 24m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/19

1:09 am-1:41 pm

1 stop13h 32m

$587

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 8/7

9:07 pm-10:19 pm

2 stops48h 12m

Santa Cruz de la Sierra Viru Viru Intl

Tue 8/19

1:09 am-7:53 am

2 stops31h 44m

$594

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Fri 8/22

7:00 am-10:19 pm

2 stops38h 19m

Santa Cruz de la Sierra Viru Viru Intl

Sat 8/30

2:55 am-10:41 pm

2 stops20h 46m

$668

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 9/16

10:54 am-1:50 am

2 stops13h 56m

Santa Cruz de la Sierra Viru Viru Intl

Fri 9/26

2:55 am-1:15 pm

1 stop11h 20m

$703

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Sun 7/27

5:25 pm-1:50 am

2 stops56h 25m

Santa Cruz de la Sierra Viru Viru Intl

Wed 7/30

2:55 am-11:54 pm

2 stops20h 59m

$750

LouisvilleSanta Cruz de la Sierra

SDF - VVI

SDFVVI

Louisville Intl

Sat 10/25

9:40 am-9:44 pm

2 stops36h 04m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/27

12:55 am-7:35 pm

2 stops18h 40m

$761

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Sat 11/1

6:00 am-9:44 pm

2 stops15h 44m

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/8

12:55 am-7:56 pm

2 stops20h 01m

$799

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

Sun 7/27

6:00 am-10:19 pm

2 stops40h 19m

Santa Cruz de la Sierra Viru Viru Intl

Thu 7/31

12:15 pm-7:02 pm

2 stops30h 47m

$1,135

South BendSanta Cruz de la Sierra

SBN - VVI

SBNVVI

South Bend/Michiana

Wed 7/23

7:30 am-10:19 pm

2 stops38h 49m

Santa Cruz de la Sierra Viru Viru Intl

Wed 8/20

1:09 am-9:40 pm

2 stops20h 31m

$1,321

DaytonSanta Cruz de la Sierra

DAY - VVI

DAYVVI

Dayton

Fri 10/3

10:25 am-1:50 am

2 stops15h 25m

Santa Cruz de la Sierra Viru Viru Intl

Mon 10/6

2:55 am-6:59 pm

2 stops16h 04m

$1,529

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 18 results
1
2

Best time to book a flight from Indiana to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Santa Cruz de la Sierra

Get insights into the airlines that provide service to Santa Cruz de la Sierra. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santa Cruz de la Sierra. Reviews last updated June 30, 2025.
Read through reviews of airlines operating flights from Indiana to Santa Cruz de la Sierra, such as LATAM Airlines, Copa Airlines, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,801 reviews

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Crew

8.1

Overall

7.5

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,801 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Crew

8.1

Overall

7.5

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Copa Airlines
7.5
Good
1,464 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Crew

8.1

Overall

7.5

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,852 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Crew

8.1

Overall

7.5

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Avianca
6.7
Okay
2,359 reviews
LATAM Airlines
7.5
Good
1,801 reviews

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Crew

8.1

Overall

7.5

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Indiana?

    For a flight from Indiana to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • What are the cheapest airlines to fly from Indiana to Santa Cruz de la Sierra one-way?

    $270 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on United Airlines and Avianca, with prices starting from $288 and $444, respectively.

  • What are the most popular routes from Indiana to Santa Cruz de la Sierra?

    Most travelers choose South Bend/Michiana - Santa Cruz de la Sierra Viru Viru Intl, Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl or Indianapolis - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for flights from Indiana to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Indiana to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Indiana to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Indiana to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Santa Cruz de la Sierra?

    Currently, October is the cheapest month in which you can book a flight from Indiana to Santa Cruz de la Sierra (average of $597). Flying from Indiana to Santa Cruz de la Sierra in December is currently the most expensive (average of $822). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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O'Hare Intl to Santa Cruz de la Sierra flights
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Reagan-National to Cochabamba flights
John F Kennedy Intl to Trinidad flights

Top airline flying from Indiana to Santa Cruz de la Sierra

Discover the top airline that operate flights from Indiana to Santa Cruz de la Sierra. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$434Average$964FlexibilityNo cancel feeOn-time69%

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