HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$296+ Cheap flights from Indiana to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
IND — VVI
Jan 2 — Jan 91
Fri 1/2
Fri 1/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indiana to Santa Cruz de la Sierra

Cheapest flights from Indiana to Santa Cruz de la Sierra
Explore the most affordable flight options available from Indiana to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 3, 2025.

This Avianca deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:50 amORD - VVI
2 stops15h 45mMultiple Airlines
Thu 1/153:40 amVVI - ORD
1 stop18h 40mMultiple Airlines
Deal found 12/2$973
This Justfly.com deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:20 pmORD - VVI
1 stop26h 15mAvianca
Thu 1/153:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 12/2$1,199
This Faresmojo deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:35 pmORD - VVI
2 stops34h 00mAvianca
Thu 1/13:40 amVVI - ORD
1 stop18h 40mAvianca
Deal found 12/2$1,234
This United Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:20 amIND - VVI
2 stops36h 26mUnited Airlines
Sat 12/2011:40 amVVI - IND
2 stops34h 16mUnited Airlines
Deal found 12/1$1,533
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:34 pmIND - VVI
2 stops34h 01mLATAM Airlines
Sat 12/2011:15 amVVI - IND
2 stops23h 33mLATAM Airlines
Deal found 12/2$1,680
This Justfly.com deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1910:20 pmORD - VVI
1 stop26h 15mAvianca
Wed 12/313:40 amVVI - ORD
2 stops17h 12mAvianca
Deal found 11/30$1,872
This Avianca deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:00 amORD - VVI
2 stops15h 35mMultiple Airlines
Wed 12/313:40 amVVI - ORD
1 stop18h 40mMultiple Airlines
Deal found 12/2$2,033

Find flight deals from Indiana to Santa Cruz de la Sierra

Keep the following information in mind while searching for Indiana to Santa Cruz de la Sierra flight deals. Data was last updated December 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$604
(United Airlines)

One-way from

$296
(Kiwi.com)
Provider with most accurate pricing for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Indiana to Santa Cruz de la Sierra that are best for you.

Fly from

Indiana

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 2/10

1:00 pm-10:50 pm

3 stops31h 50m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/5

11:42 am-2:33 pm

2 stops28h 51m

$604

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 1/29

1:00 pm-10:50 pm

2 stops31h 50m

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/5

11:44 am-12:28 am

2 stops14h 44m

$604

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 4/5

3:21 pm-3:40 am

1 stop11h 19m

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/17

1:15 am-1:58 pm

1 stop13h 43m

$607

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 3/18

8:55 am-3:38 am

2 stops17h 43m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/26

11:42 am-9:34 pm

2 stops34h 52m

$618

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 1/27

5:40 am-10:50 pm

2 stops15h 10m

Santa Cruz de la Sierra Viru Viru Intl

Thu 1/29

11:44 am-9:43 am

2 stops23h 59m

$663

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 2/10

7:34 am-10:50 pm

1 stop13h 16m

Santa Cruz de la Sierra Viru Viru Intl

Thu 3/5

11:42 am-12:04 am

1 stop14h 22m

$676

IndianapolisSanta Cruz de la Sierra

IND - VVI

INDVVI

Indianapolis

Mon 3/16

6:00 am-10:50 pm

2 stops16h 50m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/31

11:47 am-11:56 pm

2 stops36h 09m

$736

LouisvilleSanta Cruz de la Sierra

SDF - VVI

SDFVVI

Louisville Intl

Wed 2/11

9:15 am-10:50 pm

2 stops36h 35m

Santa Cruz de la Sierra Viru Viru Intl

Tue 2/17

11:44 am-2:47 pm

2 stops28h 03m

$742

South BendSanta Cruz de la Sierra

SBN - VVI

SBNVVI

South Bend/Michiana

Tue 2/24

9:45 am-10:50 pm

2 stops36h 05m

Santa Cruz de la Sierra Viru Viru Intl

Sat 2/28

11:44 am-9:39 pm

2 stops34h 55m

$856

DaytonSanta Cruz de la Sierra

DAY - VVI

DAYVVI

Dayton

Tue 4/28

10:20 am-10:42 pm

2 stops36h 22m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/2

11:47 am-9:47 am

2 stops22h 00m

$856

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 23 results
1
2
3

Best time to book a flight from Indiana to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Indiana?

    For a flight from Indiana to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • How long is the flight from Indiana to Santa Cruz de la Sierra?

    There are many flights that can get you from Indiana to Santa Cruz de la Sierra in 11h 19m. Fly via United Airlines, Copa Airlines, or LATAM Airlines to get the fastest option. The distance from Indiana to Santa Cruz de la Sierra is about 4410 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Indiana to Santa Cruz de la Sierra?

    Most travelers choose Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl, Dayton - Santa Cruz de la Sierra Viru Viru Intl or Indianapolis - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for flights from Indiana to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Indiana to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Indiana to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Indiana to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Santa Cruz de la Sierra flights
Dulles Intl to Santa Cruz de la Sierra flights
Reagan-National to Santa Cruz de la Sierra flights
John F Kennedy Intl to La Paz flights
Dulles Intl to La Paz flights
John F Kennedy Intl to Santa Cruz de la Sierra flights
Baltimore to Santa Cruz de la Sierra flights
Los Angeles to Santa Cruz de la Sierra flights
Miami to La Paz flights
Miami to Cochabamba flights
Newark to La Paz flights
Newark to Santa Cruz de la Sierra flights
LaGuardia to La Paz flights
LaGuardia to Santa Cruz de la Sierra flights
Reagan-National to La Paz flights
Hobby to Santa Cruz de la Sierra flights
George Bush Intcntl to Santa Cruz de la Sierra flights
Los Angeles to La Paz flights
Dulles Intl to Cochabamba flights
Orlando to Santa Cruz de la Sierra flights
Baltimore to La Paz flights
San Francisco to Santa Cruz de la Sierra flights
Dallas/Fort Worth to Santa Cruz de la Sierra flights
Fort Lauderdale to La Paz flights
Boston to La Paz flights
Hobby to La Paz flights
Boston to Santa Cruz de la Sierra flights
Las Vegas to Santa Cruz de la Sierra flights
O'Hare Intl to Santa Cruz de la Sierra flights
George Bush Intcntl to La Paz flights
O'Hare Intl to La Paz flights
Seattle to Santa Cruz de la Sierra flights
San Francisco to La Paz flights
Tampa to Santa Cruz de la Sierra flights
Charlotte to Santa Cruz de la Sierra flights
Salt Lake City to Santa Cruz de la Sierra flights
Dallas/Fort Worth to La Paz flights
Reagan-National to Cochabamba flights
Denver to Santa Cruz de la Sierra flights
Atlanta to La Paz flights
Austin to La Paz flights
Nashville to Santa Cruz de la Sierra flights
Love Field to Santa Cruz de la Sierra flights
Raleigh to Santa Cruz de la Sierra flights
Seattle to La Paz flights
Atlanta to Santa Cruz de la Sierra flights
Newark to Cochabamba flights
Fort Lauderdale to Santa Cruz de la Sierra flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.