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Santa Cruz de la Sierra

$271+ Cheap flights from Indiana to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
IND — VVI
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Indiana to Santa Cruz de la Sierra

Keep the following information in mind while searching for Indiana to Santa Cruz de la Sierra flight deals. Data was last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$590
(Copa Airlines)

One-way from

$271
(Copa Airlines)
Provider with most accurate pricing for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flights.
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From Indiana to Santa Cruz de la Sierra Viru Viru Intl
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One-way flight from Indiana to Santa Cruz de la Sierra Viru Viru Intl
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Find flight deals from Indiana to Santa Cruz de la Sierra

Cheapest flights from Indiana to Santa Cruz de la Sierra
Explore the most affordable flight options available from Indiana to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Copa Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:01 am
ORD
-
VVI
1 stop13h 43m
Copa Airlines
Sat 10/101:12 am
VVI
-
ORD
1 stop13h 47m
Copa Airlines
Deal found 1/12$590
This KAYAK deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:40 am
ORD
-
VVI
2 stops16h 10m
Copa Airlines
Tue 3/1711:42 am
VVI
-
ORD
2 stops22h 40m
Copa Airlines
Deal found 1/14$614
This Copa Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:06 am
ORD
-
VVI
1 stop18h 34m
Copa Airlines
Fri 4/171:15 am
VVI
-
ORD
1 stop13h 43m
Copa Airlines
Deal found 1/13$615
This KAYAK deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/243:40 pm
ORD
-
VVI
2 stops18h 35m
Multiple Airlines
Tue 4/1411:48 am
VVI
-
ORD
2 stops22h 25m
Multiple Airlines
Deal found 1/12$619
This KAYAK deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:15 pm
ORD
-
VVI
2 stops29h 23m
Copa Airlines
Sat 3/2111:42 am
VVI
-
ORD
2 stops20h 46m
Copa Airlines
Deal found 1/14$623
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/142:00 pm
ORD
-
VVI
2 stops30h 50m
United Airlines
Thu 2/1911:44 am
VVI
-
ORD
2 stops22h 02m
United Airlines
Deal found 1/12$625
This KAYAK deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:40 am
ORD
-
VVI
2 stops16h 10m
Copa Airlines
Tue 3/2411:42 am
VVI
-
ORD
2 stops23h 07m
Copa Airlines
Deal found 1/14$628
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:15 am
ORD
-
VVI
2 stops38h 35m
United Airlines
Tue 3/2411:42 am
VVI
-
ORD
2 stops37h 02m
United Airlines
Deal found 1/14$632
This KAYAK deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:15 pm
ORD
-
VVI
2 stops29h 23m
Copa Airlines
Tue 3/2411:42 am
VVI
-
ORD
2 stops23h 07m
Copa Airlines
Deal found 1/14$637
This KAYAK deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/293:21 pm
ORD
-
VVI
1 stop11h 10m
Copa Airlines
Sat 6/611:47 am
VVI
-
ORD
1 stop14h 28m
Copa Airlines
Deal found 1/14$665
This Avianca deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:15 am
ORD
-
VVI
2 stops17h 35m
Avianca
Mon 9/142:55 am
VVI
-
ORD
1 stop11h 20m
Avianca
Deal found 1/13$672
This Ovago deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/169:35 pm
ORD
-
VVI
2 stops24h 05m
Copa Airlines
Tue 9/1511:47 am
VVI
-
ORD
2 stops20h 36m
Copa Airlines
Deal found 1/13$675

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Indiana to Santa Cruz de la Sierra that are best for you.

Fly from

Indiana

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 3/11

3:22 pm-3:38 am

1 stop11h 16m

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/16

1:14 am-1:31 pm

1 stop13h 17m

$590

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 4/5

8:06 am-3:40 am

1 stop18h 34m

Santa Cruz de la Sierra Viru Viru Intl

Fri 4/17

1:15 am-1:58 pm

1 stop13h 43m

$615

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 3/12

9:15 pm-3:38 am

2 stops29h 23m

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/17

11:42 am-9:22 am

2 stops22h 40m

$623

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Thu 3/12

9:15 pm-3:38 am

2 stops29h 23m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/21

11:42 am-7:28 am

2 stops20h 46m

$623

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Mon 5/4

7:23 am-3:31 am

2 stops19h 08m

Santa Cruz de la Sierra Viru Viru Intl

Sat 5/9

11:47 am-7:23 am

2 stops20h 36m

$625

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Tue 4/21

7:41 pm-10:42 pm

2 stops26h 01m

Santa Cruz de la Sierra Viru Viru Intl

Sat 4/25

11:48 am-9:13 am

2 stops22h 25m

$625

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Wed 2/18

2:30 pm-10:50 pm

2 stops30h 20m

Santa Cruz de la Sierra Viru Viru Intl

Mon 2/23

11:44 am-9:18 am

2 stops23h 34m

$625

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sun 4/12

5:49 am-10:42 pm

2 stops15h 53m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

11:48 am-11:16 am

2 stops24h 28m

$625

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 4/11

5:49 am-10:42 pm

2 stops15h 53m

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/21

11:48 am-11:27 am

2 stops24h 39m

$625

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

Sat 2/28

6:20 pm-10:50 pm

2 stops26h 30m

Santa Cruz de la Sierra Viru Viru Intl

Sat 3/7

11:42 am-6:28 am

2 stops20h 46m

$625

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 33 results
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Best time to book a flight from Indiana to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Indiana?

    For a flight from Indiana to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • How long is the flight from Indiana to Santa Cruz de la Sierra?

    There are many flights that can get you from Indiana to Santa Cruz de la Sierra in 11h 16m. Fly via Copa Airlines or United Airlines to get the fastest option. The distance from Indiana to Santa Cruz de la Sierra is about 4410 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Indiana to Santa Cruz de la Sierra?

    Most travelers choose Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl, Cincinnati Cinci./N. Kentucky - Santa Cruz de la Sierra Viru Viru Intl or South Bend/Michiana - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for flights from Indiana to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Indiana to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Indiana to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Indiana to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Indiana to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
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