HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santa Cruz de la Sierra

$226+ Cheap flights from Indiana to Santa Cruz de la Sierra (VVI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
IND — VVI
nov. 7 — nov. 141
vie. 11/7
vie. 11/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Indiana to Santa Cruz de la Sierra with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Indiana to Santa Cruz de la Sierra

Cheapest flights from Indiana to Santa Cruz de la Sierra
Explore the most affordable flight options available from Indiana to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 8, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/203:07 pmORD - VVI
1 stop11h 29mCopa Airlines
jue. 10/231:09 amVVI - ORD
1 stop13h 32mCopa Airlines
Deal found 10/8$417
This Booking.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/183:07 pmORD - VVI
1 stop30h 33mCopa Airlines
lun. 11/31:09 amVVI - ORD
1 stop13h 37mCopa Airlines
Deal found 10/6$445
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:56 amORD - VVI
1 stop13h 50mCopa Airlines
lun. 11/1711:40 amVVI - ORD
1 stop14h 25mCopa Airlines
Deal found 10/7$502
This Copa Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/106:56 amORD - VVI
1 stop13h 50mCopa Airlines
sáb. 11/151:09 amVVI - ORD
1 stop13h 37mCopa Airlines
Deal found 10/6$528
This Copa Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/177:59 amORD - VVI
1 stop13h 41mCopa Airlines
vie. 10/241:09 amVVI - ORD
1 stop13h 32mCopa Airlines
Deal found 10/7$571
This Mytrip deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/35:10 amORD - VVI
2 stops19h 25mMultiple Airlines
mar. 11/113:40 amVVI - ORD
1 stop18h 40mMultiple Airlines
Deal found 10/7$591
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/179:20 pmORD - VVI
2 stops24h 20mUnited Airlines
mar. 11/41:09 amVVI - ORD
2 stops32h 32mUnited Airlines
Deal found 10/7$593
This Trip.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/177:59 amORD - VVI
1 stop13h 41mCopa Airlines
mar. 11/411:40 amVVI - ORD
1 stop27h 06mCopa Airlines
Deal found 10/6$599
This United deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/69:08 pmORD - VVI
2 stops23h 38mMultiple Airlines
mié. 11/123:40 amVVI - ORD
2 stops21h 30mMultiple Airlines
Deal found 10/7$602
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/209:20 pmORD - VVI
2 stops24h 20mUnited Airlines
jue. 10/231:09 amVVI - ORD
2 stops31h 32mUnited Airlines
Deal found 10/8$604
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:15 pmORD - VVI
2 stops51h 25mUnited Airlines
vie. 10/241:09 amVVI - ORD
2 stops31h 33mUnited Airlines
Deal found 10/5$611
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/172:10 pmORD - VVI
2 stops55h 30mUnited Airlines
vie. 10/241:09 amVVI - ORD
2 stops23h 06mUnited Airlines
Deal found 10/5$613

Cheap flight deals from Indiana to Santa Cruz de la Sierra

Keep the following information in mind while searching for Indiana to Santa Cruz de la Sierra flight deals. Data was last updated octubre 8, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$417
(Copa Airlines)

One-way from

$226
(Kiwi.com)
Provider with most accurate pricing for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-Santa Cruz de la Sierra Viru Viru Intl flights.
Search Deals
From Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals
One-way flight from Indiana to Santa Cruz de la Sierra Viru Viru Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 8, 2025.
Use the filters below to find and compare flights from Indiana to Santa Cruz de la Sierra that are best for you.

Fly from

Indiana

Fly to

Santa Cruz de la Sierra

Route

Depart

Return

Price

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 11/10

6:56 am-10:46 pm

1 stop13h 50m

Santa Cruz de la Sierra Viru Viru Intl

dom. 11/16

1:09 am-12:46 pm

1 stop13h 37m

$417

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

dom. 10/19

7:59 am-10:40 pm

1 stop13h 41m

Santa Cruz de la Sierra Viru Viru Intl

mar. 11/4

11:40 am-12:05 am

1 stop14h 25m

$417

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 10/20

7:59 am-10:40 pm

1 stop13h 41m

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/23

1:09 am-1:41 pm

1 stop13h 32m

$417

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

sáb. 10/18

9:20 pm-10:40 pm

2 stops24h 20m

Santa Cruz de la Sierra Viru Viru Intl

mar. 10/21

1:09 am-12:14 am

2 stops24h 05m

$604

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

dom. 10/19

6:00 am-10:40 pm

2 stops15h 40m

Santa Cruz de la Sierra Viru Viru Intl

lun. 11/3

1:09 am-12:15 am

2 stops25h 06m

$604

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

dom. 10/19

6:00 am-10:40 pm

2 stops15h 40m

Santa Cruz de la Sierra Viru Viru Intl

jue. 10/23

1:09 am-9:36 am

2 stops33h 27m

$604

ChicagoSanta Cruz de la Sierra

ORD - VVI

ORDVVI

Chicago O'Hare Intl

lun. 11/10

9:10 pm-10:46 pm

2 stops23h 36m

Santa Cruz de la Sierra Viru Viru Intl

dom. 11/16

1:09 am-9:17 pm

2 stops22h 08m

$604

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

mar. 11/11

6:01 am-2:35 am

2 stops43h 34m

Santa Cruz de la Sierra Viru Viru Intl

lun. 11/24

3:40 am-10:54 am

2 stops32h 14m

$731

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

mié. 11/12

5:03 pm-2:35 am

2 stops32h 32m

Santa Cruz de la Sierra Viru Viru Intl

mar. 11/25

1:09 am-11:44 pm

2 stops23h 35m

$732

CincinnatiSanta Cruz de la Sierra

CVG - VVI

CVGVVI

Cincinnati Cinci./N. Kentucky

mié. 11/12

7:00 am-10:46 pm

2 stops14h 46m

Santa Cruz de la Sierra Viru Viru Intl

mar. 11/25

1:09 am-9:30 am

2 stops33h 21m

$734

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/6

Showing 1-10 of 40 results
1
2
3
4

Best time to book a flight from Indiana to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Santa Cruz de la Sierra
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Indiana to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santa Cruz de la Sierra from Indiana?

    For a flight from Indiana to Santa Cruz de la Sierra, you will be flying into Viru Viru Intl. Santa Cruz de la Sierra Viru Viru Intl (VVI) is just 11.5 mi from the center of the city.

  • How long is the flight from Indiana to Santa Cruz de la Sierra?

    There are many flights that can get you from Indiana to Santa Cruz de la Sierra in 13h 50m. Fly via Copa Airlines or United Airlines to get the fastest option. The distance from Indiana to Santa Cruz de la Sierra is about 4410 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Indiana to Santa Cruz de la Sierra?

    Most travelers choose Chicago O'Hare Intl - Santa Cruz de la Sierra Viru Viru Intl, Cincinnati Cinci./N. Kentucky - Santa Cruz de la Sierra Viru Viru Intl or Indianapolis - Santa Cruz de la Sierra Viru Viru Intl when deciding on the best route from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for flights from Indiana to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Indiana to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Indiana to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Indiana to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indiana to Santa Cruz de la Sierra

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Santa Cruz de la Sierra flights
Dulles Intl to Santa Cruz de la Sierra flights
Reagan-National to Santa Cruz de la Sierra flights
Miami to La Paz flights
Dulles Intl to La Paz flights
Baltimore to Santa Cruz de la Sierra flights
John F Kennedy Intl to La Paz flights
Los Angeles to Santa Cruz de la Sierra flights
John F Kennedy Intl to Santa Cruz de la Sierra flights
Reagan-National to La Paz flights
Newark to Santa Cruz de la Sierra flights
LaGuardia to Santa Cruz de la Sierra flights
O'Hare Intl to Santa Cruz de la Sierra flights
LaGuardia to La Paz flights
San Francisco to Santa Cruz de la Sierra flights
Baltimore to La Paz flights
Dallas/Fort Worth to Santa Cruz de la Sierra flights
Los Angeles to La Paz flights
Boston to Santa Cruz de la Sierra flights
Fort Lauderdale to La Paz flights
Atlanta to Santa Cruz de la Sierra flights
Miami to Cochabamba flights
Newark to La Paz flights
Hobby to Santa Cruz de la Sierra flights
George Bush Intcntl to Santa Cruz de la Sierra flights
Dulles Intl to Cochabamba flights
O'Hare Intl to La Paz flights
Salt Lake City to Santa Cruz de la Sierra flights
Sky Harbor Intl to Santa Cruz de la Sierra flights
Hobby to La Paz flights
Orlando to Santa Cruz de la Sierra flights
San Francisco to La Paz flights
Boston to La Paz flights
George Bush Intcntl to La Paz flights
Orlando to La Paz flights
Seattle to Santa Cruz de la Sierra flights
Atlanta to La Paz flights
Love Field to Santa Cruz de la Sierra flights
San Diego to Santa Cruz de la Sierra flights
Tampa to Santa Cruz de la Sierra flights
Reagan-National to Cochabamba flights
John F Kennedy Intl to Uyuni flights
Denver to Santa Cruz de la Sierra flights
Fort Lauderdale to Santa Cruz de la Sierra flights
Minneapolis to Santa Cruz de la Sierra flights
Austin to La Paz flights
Nashville to Santa Cruz de la Sierra flights
Baltimore to Cochabamba flights
Charlotte to Santa Cruz de la Sierra flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.